Aliases & Classifications for Oligospermia

About this section
Sources:
9Disease Ontology, 11DISEASES, 60UMLS, 43Novoseek, 22GTR, 33MeSH, 38NCIt, 27ICD9CM
See all sources

Oligospermia, Aliases & Descriptions:

Name: Oligospermia 9 11 60
 
Oligozoospermia 9 43 22


External Ids:

Disease Ontology9 DOID:14228
MeSH33 D009845
NCIt38 C34860
ICD9CM27 606.1

Summaries for Oligospermia

About this section


Wikipedia:63 Oligozoospermia, refers to semen with a low concentration of sperm and is a common finding in male... more...

MalaCards based summary: Oligospermia, also known as oligozoospermia, is related to y chromosome infertility and sertoli cell-only syndrome. An important gene associated with Oligospermia is AZF1 (azoospermia factor 1). The compounds dutasteride and finasteride have been mentioned in the context of this disorder. Affiliated tissues include testis and pituitary, and related mouse phenotypes are homeostasis/metabolism and endocrine/exocrine gland.

Related Diseases for Oligospermia

About this section

Diseases related to Oligospermia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1y chromosome infertility31.0DAZ1
2sertoli cell-only syndrome30.8DAZ1, DAZ2
3varicocele30.8AZF1, PRL
4cryptorchidism30.1AR, AZF1, DAZ1
5male infertility30.0AR, PRL, CFTR
6azoospermia29.8AZF1, DAZ2, DAZ4, DAZ1, CFTR, TSSK6
7gynecomastia29.7AR, SRD5A2, PRL
8hypogonadism29.4TF, GNRHR, PRL, AR
9infertility29.3AR, GSTT1, PRL, GNRHR, CFTR, AZF1
10smith-magenis syndrome10.3DAZ1, AZF1
11bronchiectasis oligospermia10.3
12cervicitis10.2
13penis agenesis10.2AR, SRD5A2
14alopecia, androgenetic, 110.2SRD5A2, AR
15androgen insensitivity10.2AR, SRD5A2
16pseudohermaphroditism10.1AR, SRD5A2
17bronchiectasis10.1
18impotence10.1
19psoriasis10.1
20blindness10.1
21nutritional deficiency disease10.1CFTR, TF
22hypospadias10.1AR, SRD5A2
23galactosemia10.1CHKB, TF
24neuromuscular disease10.1GNRHR, CHKB, AR
25precocious puberty10.0PRL, GNRHR
26hyperprolactinemia10.0
27cystic fibrosis10.0
28spermatogenic failure, y-linked, 210.0
29obesity10.0
30kallmann syndrome10.0
31spinocerebellar ataxia10.0
32testicular disease10.0
33ataxia10.0
34prostatic hypertrophy10.0AR, PRL
35schizophrenia10.0
36short stature, onychodysplasia, facial dysmorphism, and hypotrichosis10.0
37myotonic dystrophy 210.0
38williams-beuren syndrome10.0
39spermatogenic failure 710.0
40fanconi anemia, complementation group a10.0
41oculocerebrorenal syndrome10.0
42hyperglycemia10.0
43testicular cancer10.0
4448,xxxy syndrome10.0
4548,xxyy syndrome10.0
4649,xxxxy syndrome10.0
47deafness-infertility syndrome10.0
48hypereosinophilic syndrome10.0
49ring chromosome 1210.0
50testotoxicosis10.0

Graphical network of the top 20 diseases related to Oligospermia:



Diseases related to oligospermia

Symptoms for Oligospermia

About this section

Drugs & Therapeutics for Oligospermia

About this section

Drug clinical trials:

Search ClinicalTrials for Oligospermia

Search NIH Clinical Center for Oligospermia

Genetic Tests for Oligospermia

About this section

Genetic tests related to Oligospermia:

id Genetic test Affiliating Genes
1 Oligozoospermia22

Anatomical Context for Oligospermia

About this section

MalaCards organs/tissues related to Oligospermia:

31
Testis, Pituitary

Animal Models for Oligospermia or affiliated genes

About this section

MGI Mouse Phenotypes related to Oligospermia:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.8CFTR, GNRHR, CHKB, PRL, GSTT1, AR
2MP:00053797.5PYGO2, CFTR, GNRHR, PRL, SRD5A2, KLHL10
3MP:00053896.9AR, PYGO2, CFTR, GNRHR, TSSK6, PRL

Publications for Oligospermia

About this section

Articles related to Oligospermia:

(show top 50)    (show all 170)
idTitleAuthorsYear
1
Testis-specific Fank1 gene in knockdown mice produces oligospermia via apoptosis. (24369145)
2014
2
Association of polymorphisms in glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) with idiopathic azoospermia or oligospermia in Sichuan, China. (25532576)
2014
3
De novo 15.5-Mb Interstitial Deletion in 5p in a Male Ascertained by Oligospermia. (23885232)
2013
4
Semen cryopreservation for men banking for oligospermia, cancers, and other pathologies: prediction of post-thaw outcome using basal semen quality. (24034937)
2013
5
ICSI outcome of patients with severe oligospermia vs. non-obstructive azoospermia. (22905450)
2012
6
Effect of Curculigo orchioides on hyperglycemia-induced oligospermia and sexual dysfunction in male rats. (21918533)
2012
7
Re: Low-dose lisinopril in normotensive men with idiopathic oligospermia and infertility: a 5-year randomized, controlled, crossover pilot study. (23141270)
2012
8
Microsurgical varicocelectomy for infertile men with oligospermia: differential effect of bilateral and unilateral varicocele on pregnancy outcomes. (19338535)
2009
9
Mutation of KLHL-10 in idiopathic infertile males with azoospermia, oligospermia or asthenospermia]. (20218307)
2009
10
Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia. (17941933)
2008
11
Ring chromosome 12 and severe oligospermia: a case report. (17880954)
2008
12
Azoospermia after treatment with clomiphene citrate in patients with oligospermia. (18555230)
2008
13
May antioxidant therapy improve sperm parameters of men with persistent oligospermia after retrograde embolization for varicocele? (17982752)
2008
14
Development of l-CDB-4022 as a nonsteroidal male oral contraceptive: induction and recovery from severe oligospermia in the adult male cynomolgus monkey (Macaca fascicularis). (17218411)
2007
15
An infertile couple suffering from oligospermia by partial sperm maturation arrest: can phytoestrogens play a therapeutic role? A case report study. (16864151)
2006
16
Male infertility: Y-chromosome deletion and testicular aetiology in cases of azoo-/oligospermia. (16313071)
2005
17
Rapamycin-induced oligospermia. (14501876)
2003
18
Testicular fine needle aspiration cytology for the diagnosis of azoospermia and oligospermia. (10833990)
2000
19
Absence of microdeletions in the Y chromosome in patients with a history of cryptorchidism and azoospermia or oligospermia. (10202881)
1999
20
Biochemical parameters in evaluation of oligospermia. (8089906)
1994
21
Intrauterine insemination as a successful method in the treatment of infertility caused by oligospermia. (7985455)
1993
22
Serum levels of steroid hormones in men with varicocele and oligospermia as compared to normozoospermic men. (1305061)
1992
23
Episodic luteinizing hormone release in idiopathic oligospermia. (1981212)
1990
24
Immunological studies in patients with oligospermia. (2806606)
1989
25
Cluster of oligospermia among four men occupationally exposed to methylene chloride (MeCl) (2520532)
1989
26
Possibilities of association of azoospermia and oligospermia with some HLA system antigens. (3162459)
1988
27
Treatment of severe oligospermia with human chorionic gonadotropin/human menopausal gonadotropin: a placebo-controlled, double blind trial. (3119647)
1987
28
Demonstrated paternity in spite of severe idiopathic oligospermia. (3469106)
1987
29
Tamoxifen and oligospermia. (3938205)
1985
30
The limitations of in vitro fertilization from males with severe oligospermia and abnormal sperm morphology. (6336098)
1984
31
Differential effect of luteinizing hormone-releasing hormone infusion on testicular steroids in normal men and patients with idiopathic oligospermia. (6430726)
1984
32
Increased sperm count in 25 cases of idiopathic normogonadotropic oligospermia following treatment with tamoxifen. (6404663)
1983
33
Mechanism for delivery of sperm to fimbria in oligospermia. (7201413)
1982
34
The levels of the male serum and seminal fluid prolactin in oligospermia and azoospermia. (6114065)
1981
35
The occurrence of gynecomastia upon withdrawal of clomiphene citrate treatment for idiopathic oligospermia. (6773824)
1980
36
Improved semen quality in subfertile males with varicocele-associated oligospermia following treatment with clomiphene citrate. (7364070)
1980
37
Effect of synthetic LH-RH and hCG administration on plasma testosterone, androstenedione, and estradiol 17beta levels in normal men and in patients with idiopathic oligospermia. (37185)
1979
38
Oligospermia secondary to mA1llerian duct cyst. Simple surgical cure. (664145)
1978
39
Elevated urinary levels of 5-hydroxyindole acetic acid and its relationship among levels of plasma follicle stimulating hormone, testosterone and testicular pathology in patients with severe oligospermia and/or azoospermia. (916056)
1977
40
Search for transit difficulties in the epididymis for differential diagnosis of oligospermia]. (961325)
1976
41
Elevated urinary levels of 5-hydroxyindole acetic acid and its relationship among levels of plasma follicle stimulating hormone, testosterone and testicular pathology in patients with severe oligospermia and/or azoospermia. (1030546)
1976
42
The first pregnancies after treating of oligospermia by collected and stored human semen. (1143102)
1975
43
Estimation of number, mean size and size distribution of human spermatozoa in oligospermia using a Coulter counter. (4430992)
1974
44
Human menopausal gonadotropins in the treatment of patients with oligospermia. (4422230)
1974
45
Therapeutic effect of synthetic luteinizing hormone-releasing hormone (LH-RH) in male infertility due to idiopathic azoospermia and oligospermia. (4575636)
1973
46
Treatment of oligospermia with urinary human menopausal gonadotrophin: a preliminary report. (5921777)
1966
47
TREATMENT OF OLIGOSPERMIA WITH LARGE DOSES OF HUMAN CHORIONIC GONADOTROPIN. (14057786)
1963
48
Oligospermia and pregnancy; a study of 34 cases. (13152582)
1954
49
Influence of small doses of stilbestrol on oligospermia. (12991390)
1952
50
Influence of arginine on oligospermia. (20250427)
1947

Variations for Oligospermia

About this section

Expression for genes affiliated with Oligospermia

About this section
Search GEO for disease gene expression data for Oligospermia.

Pathways for genes affiliated with Oligospermia

About this section

Compounds for genes affiliated with Oligospermia

About this section

Compounds related to Oligospermia according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1dutasteride43 1211.2AR, SRD5A2
2finasteride43 59 24 1213.0AR, SRD5A2
3leuprolide acetate4310.0GNRHR, PRL
4buserelin43 28 1212.0GNRHR, PRL
5streptomycin49 43 1212.0TF, GSTT1
6nandrolone decanoate43 1210.9TF, AR
7silver nitrate439.9TF, CFTR
8rsai439.8GSTT1, SRD5A2
9leuprolide43 59 28 1212.8GNRHR, PRL, AR
10Hydrogen carbonate249.8CFTR, TF
11fe3+439.8TF, CHKB
12mgatp439.8CHKB, CFTR
13danazol43 24 1211.8AR, PRL, GNRHR
14gentamicin43 1210.7CFTR, TF
15triamcinolone acetonide43 2810.7CFTR, TF
16cyproteroneacetate439.7PRL, AR
17androstenedione43 2410.7PRL, SRD5A2, AR
18bicarbonate439.7TF, CFTR, CHKB
19polyethylene glycol439.6PRL, CHKB, TF
20citrate439.6TF, CFTR, CHKB
21adenine43 24 1211.6AR, SRD5A2, TF
22levonorgestrel43 59 28 1212.5PRL, AR
23vitamin d439.5CFTR, CHKB, SRD5A2, AR
24thyroxine43 2410.5TF, CHKB, PRL
25valine439.4CFTR, SRD5A2, GSTT1, AR
26doxorubicin43 49 1211.4CFTR, GNRHR, GSTT1, AR
27gnrh439.3AR, PRL, GNRHR, CFTR
28adenylate439.3CFTR, GNRHR, CHKB, AR
29n acetylcysteine439.3TF, CFTR, CHKB, AR
30levodopa43 1210.3AR, PRL, CHKB, TF
31cocaine43 1210.3AR, PRL, CHKB, TF
32paraffin439.2TF, CFTR, CHKB, AR
33pge2439.2AR, CHKB, CFTR, TF
34norepinephrine43 24 1211.2PRL, CHKB, CFTR, TF
35dihydrotestosterone43 28 24 1212.2GNRHR, CHKB, PRL, SRD5A2, AR
36progesterone43 28 59 24 1213.2GNRHR, PRL, SRD5A2, AR
37aspartate439.2TF, CFTR, CHKB, AR
38estradiol43 24 1211.2GNRHR, CHKB, PRL, SRD5A2, AR
39agar439.0AR, CHKB, TF
40glutamine439.0TF, CFTR, CHKB, SRD5A2, AR
41ascorbic acid43 2410.0TF, CFTR, CHKB, GSTT1, AR
42alanine439.0TF, CFTR, GNRHR, CHKB, SRD5A2
43tamoxifen43 49 28 1212.0TF, GNRHR, CHKB, PRL, AR
44glutamate438.9TF, CFTR, GNRHR, CHKB, AR
45dopamine43 28 24 1211.9PRL, CHKB, GNRHR, CFTR, TF
46epinephrine43 24 1210.9AR, PRL, CHKB, CFTR, TF
47steroid438.8GNRHR, CHKB, PRL, SRD5A2, GSTT1, AR
48arginine438.8GNRHR, CHKB, PRL, SRD5A2, GSTT1, AR
49estrogen437.9TF, CFTR, GNRHR, CHKB, PRL, SRD5A2
50testosterone43 59 24 1210.9AR, DAZ1, DAZ4, CFTR, GNRHR, CHKB

GO Terms for genes affiliated with Oligospermia

About this section

Biological processes related to Oligospermia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell differentiationGO:00301549.0SRD5A2, DAZ2, DAZ4, DAZ1
2multicellular organismal developmentGO:00072757.9TSSK6, GNRHR, DAZ2, DAZ4, DAZ1

Products for genes affiliated with Oligospermia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Oligospermia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet