OPCA
MCID: OLV001
MIFTS: 77

Olivopontocerebellar Atrophy (OPCA) malady

Neuronal diseases, Cardiovascular diseases, Nephrological diseases, Fetal diseases categories

Summaries for Olivopontocerebellar Atrophy

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21Genetics Home Reference, 42NIH Rare Diseases, 43NINDS, 63Wikipedia, 46OMIM, 19GeneReviews, 32MalaCards
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NIH Rare Diseases:42 Olivopontocerebellar atrophy is a progressive disease that causes areas deep in the brain, just above the spinal cord, to shrink. the main symptom is clumsiness (ataxia) that slowly gets worse. there may also be problems with balance, slurring of speech, and difficulty walking. olivopontocerebellar atrophy can be passed down through families (inherited form), or it may affect people without a known family history (sporadic form). symptoms tend to start at a younger age in people with the inherited form of the condition. there is no specific treatment or cure for this disease. therapy is aimed at treating symptoms and preventing complications. last updated: 2/9/2011

MalaCards: Olivopontocerebellar Atrophy, also known as spinocerebellar ataxia type 2, is related to spinocerebellar ataxia type 3 and multiple system atrophy, and has symptoms including hypoplastic left heart/ventricle, oligoamnios and high forehead. An important gene associated with Olivopontocerebellar Atrophy is ATXN2 (ataxin 2), and among its related pathways are Sympathetic Nerve Pathway (Pre- and Post- Ganglionic Junction) and Alpha-synuclein signaling. The compounds d amphetamine and ibotenic acid have been mentioned in the context of this disorder. Affiliated tissues include brain, cerebellum and eye, and related mouse phenotypes are endocrine/exocrine gland and homeostasis/metabolism.

Genetics Home Reference:21 Spinocerebellar ataxia type 1 (SCA1) is a condition characterized by progressive problems with movement. People with this condition initially experience problems with coordination and balance (ataxia). Other signs and symptoms of SCA1 include speech and swallowing difficulties, muscle stiffness (spasticity), and weakness in the muscles that control eye movement (ophthalmoplegia). Eye muscle weakness leads to rapid, involuntary eye movements (nystagmus). Individuals with SCA1 may have difficulty processing, learning, and remembering information (cognitive impairment).

NINDS:43 Olivopontocerebellar atrophy (OPCA) is a term that describes the degeneration of neurons in specific areas of the brain ? the cerebellum, pons, and inferior olives.

Wikipedia:63 Olivopontocerebellar atrophy (OPCA) is the degeneration of neurons in specific areas of the brain –... more...

Description from OMIM:46 164500,164400,183090

GeneReviews summary for sca1

GeneReviews summary for sca2

Aliases & Classifications for Olivopontocerebellar Atrophy

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8Disease Ontology, 9diseasecard, 19GeneReviews, 42NIH Rare Diseases, 20GeneTests, 22GTR, 21Genetics Home Reference, 43NINDS, 46OMIM, 44Novoseek, 48Orphanet, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 35MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Classifications:



Characteristics (Orphanet epidemiological data):

48
thomas syndrome:
Age of onset: Neonatal/infancy
spinocerebellar ataxia type 1:
Inheritance: Autosomal dominant; Prevalence: 1-9/100000; Age of onset: Variable
spinocerebellar ataxia type 2:
Inheritance: Autosomal dominant; Prevalence: 1-9/100000; Age of onset: Variable


Aliases & Descriptions:

olivopontocerebellar atrophy 8 42 43
spinocerebellar ataxia type 2 19 42 20 22 21 44 48 60
spinocerebellar ataxia type 1 19 20 22 21 44 48 60
spinocerebellar ataxia 1 8 9 42 46
spinocerebellar ataxia 2 8 9 42 46
olivopontocerebellar atrophy 1 42 60
olivopontocerebellar atrophy 2 42 60
olivopontocerebellar atrophies 44 60
thomas syndrome 42 48
sca 2 19 42
sca2 21 48
sca1 21 48
potter sequence - cleft lip/palate - cardiopathy 48
olivopontocerebellar atrophy holguin type 42
olivopontocerebellar degeneration 8
cerebelloparenchymal disorder 1 42
olivopontocerebellar atrophy i 21
olivopontocerebellar atrophy 4 42
type 1 spinocerebellar ataxia 21
spinocerebellar atrophy i 21
dejerine-thomas syndrome 8
wadia-swami syndrome 8
thomas' syndrome 8
menzel type opca 42
opca1 42
sdsem 42
sca 1 19
opca 42


External Ids:

Disease Ontology8 DOID:14784
MeSH34 D009849
NCIt39 C84947
MESH via Orphanet35 C536514
ICD10 via Orphanet26 Q87.8, G11
UMLS via Orphanet61 C2931225, C0752120, C0752121

Related Diseases for Olivopontocerebellar Atrophy

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17GeneCards, 18GeneDecks
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Diseases related to Olivopontocerebellar Atrophy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 137)
idRelated DiseaseScoreTop Affiliating Genes
1spinocerebellar ataxia type 331.0RPS27A, SNCA, ATXN2, ATXN7, ATXN1, SLC6A3
2multiple system atrophy30.9TSPO, RPS27A, SLC6A3, TH, GLUD1, MAPT
3dementia30.6RPS27A, SNCA, CHAT, MAP2, MAPT, TH
4muscular atrophy30.5MAP1B
5striatonigral degeneration30.5RPS27A, SNCA, MAP2, SLC6A3
6dentatorubral-pallidoluysian atrophy30.5ATXN2, ATXN1
7spinocerebellar ataxia type 730.3ATXN7, ATXN2
8spinocerebellar ataxia30.3ATXN2, ATXN2L, ATXN1
9parkinson's disease30.3SLC6A3, TH, MAPT, SNCA, RPS27A
10alzheimer's disease30.3RPS27A, SNCA, CHAT, MAP1B, MAP2, MAPT
11ophthalmoplegia30.3ATXN7
12multiple sclerosis30.3MAP2, GLUD1, TSPO
13huntington's disease30.3ATXN1, CHAT
14amyloidosis30.3MAPT, SNCA, RPS27A
15central nervous system disease30.3CHAT, MAPT, SLC6A3
16spinocerebellar ataxia type 1230.3ATXN2, ATXN7, ATXN1
17mood disorder30.2MAP2, TH, SLC6A3
18brain disease30.1TSPO, TH, MAPT, CHAT, SNCA
19schizophrenia30.1SNCA, ATXN1, CHAT, MAP1B, MAP2, GLUD1
20spinocerebellar degeneration30.1GLUD1, ATXN1, ATXN2, RPS27A
21lateral sclerosis30.1SNCA, MAPT
22movement disease30.1SNCA, TH
23motor neuron disease30.1RPS27A, SNCA, MAPT
24amyotrophic lateral sclerosis30.0RPS27A, SNCA, ATXN2, TSPO, SLC6A3, CHAT
25hereditary ataxia30.0ATXN2, ATXN7, ATXN1
26essential tremor30.0SNCA, SLC6A3
27myocardial infarction29.8NPPA
28bipolar disorder29.8TSPO, SLC6A3, TH, MAP2
29cerebritis10.5
30cervicitis10.4
31spinocerebellar ataxia type 1010.4
32neuronitis10.4
33retinal degeneration10.4
34retinitis10.4
35neuropathy10.4
36peripheral neuropathy10.4
37adrenoleukodystrophy10.3
38cerebellar ataxia10.3
39spinal muscular atrophy10.3
40olivopontocerebellar atrophy deafness10.3
41argyll robertson pupil10.2
42episodic ataxia10.2
43restless legs syndrome10.2
44transthyretin amyloidosis10.2
45stiff-person syndrome10.2
46cone dystrophy10.2
47cerebellar disease10.2
48nervous system disease10.2
49familial transthyretin amyloidosis10.2
50spinocerebellar ataxia with axonal neuropathy, autosomal recessive10.2

Graphical network of the top 20 diseases related to Olivopontocerebellar Atrophy:



Diseases related to olivopontocerebellar atrophy

Clinical Features for Olivopontocerebellar Atrophy

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46OMIM, 48Orphanet
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Clinical features from OMIM:

164500,164400,183090

Clinical synopsis from OMIM:

164400

Symptoms:

48 (show all 12)
  • hypoplastic left heart/ventricle
  • oligoamnios
  • high forehead
  • autosomal recessive inheritance
  • early death/lethality
  • congenital cardiac anomaly/malformation/cardiopathy
  • dolichocephaly/scaphocephaly
  • multicystic kidney/renal dysplasia
  • agenesis/hypoplasia/aplasia of kidneys
  • cleft lip and palate
  • downslanted palpebral fissures/anti-mongoloid slanting palpebral fissures
  • hypertelorism

Drugs & Therapeutics for Olivopontocerebellar Atrophy

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Olivopontocerebellar Atrophy

Drug clinical trials:

Search ClinicalTrials for Olivopontocerebellar Atrophy

Search NIH Clinical Center for Olivopontocerebellar Atrophy

Search CenterWatch for Olivopontocerebellar Atrophy

Genetic Tests for Olivopontocerebellar Atrophy

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20GeneTests, 22GTR
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Genetic tests related to Olivopontocerebellar Atrophy:

id Genetic test Affiliating Genes
1 Spinocerebellar Ataxia Type 120 ATXN1
2 Spinocerebellar Ataxia Type 220 ATXN2
3 Spinocerebellar Ataxia 222
4 Spinocerebellar Ataxia 122

Anatomical Context for Olivopontocerebellar Atrophy

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32MalaCards
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MalaCards organs/tissues related to Olivopontocerebellar Atrophy:

32
Brain, Cerebellum, Eye, Pons, Spinal cord, Kidney, Cortex, Heart, Skin

Animal Models for Olivopontocerebellar Atrophy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Olivopontocerebellar Atrophy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053799.1SLC6A3, TH, VRK1, GNAI2, SNCA, ATXN2
2MP:00053768.2MAP1B, CHAT, ATXN1, ATXN2, GLUD1, SNCA
3MP:00107688.2GNAI2, SLC6A3, ATXN7, SNCA, ATXN2, ATXN1
4MP:00053788.1ATXN7, SNCA, GNAI2, ATXN2, ATXN1, CHAT
5MP:00053868.1TH, SNCA, ATXN7, ATXN2, ATXN1, CHAT
6MP:00036318.1SLC6A3, TH, SNCA, ATXN2, ATXN7, ATXN1

Publications for Olivopontocerebellar Atrophy

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50PubMed
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Articles related to Olivopontocerebellar Atrophy:

(show top 50)    (show all 183)
idTitleAuthorsYear
1
The efficacy of combined estrogen and buspirone treatment in olivopontocerebellar atrophy. (18466925)
2008
2
Olivopontocerebellar atrophy: toward a better nosological definition. (16874757)
2006
3
Olivopontocerebellar atrophy in two adult cats, sporadic cases or new genetic entity. (14715964)
2004
4
Motor learning processes in a movement-scaling task in olivopontocerebellar atrophy and Parkinson's disease. (12898095)
2003
5
Unusual association of sporadic olivopontocerebellar atrophy and motor neuron disease. (12522682)
2002
6
Patterns of neuropsychological performance in multiple system atrophy compared to sporadic and hereditary olivopontocerebellar atrophy. (12464189)
2002
7
Evolution of sporadic olivopontocerebellar atrophy into multiple system atrophy. (10953186)
2000
8
Preclinical impairment of the striatal dopamine transporter system in sporadic olivopontocerebellar atrophy: studied with [(123)I]beta-CIT and SPECT. (10601804)
2000
9
A case of nocturnal polyuria in olivopontocerebellar atrophy. (10459712)
1999
10
A case of spinocerebellar ataxia type 6 mimicking olivopontocerebellar atrophy. (10450843)
1999
11
Purkinje cells in olivopontocerebellar atrophy and granule cell-type cerebellar degeneration: an immunohistochemical study. (9678515)
1998
12
Neurobehavioral dimensions of olivopontocerebellar atrophy. (9672819)
1998
13
Olivopontocerebellar atrophy leading to recognition of carbohydrate-deficient glycoprotein syndrome type I. (8923302)
1996
14
Tracheostomy can make a difference in recurrent respiratory failure secondary to olivopontocerebellar atrophy. (8830454)
1996
15
Glial and neuronal cytoplasmic inclusions in familial olivopontocerebellar atrophy. (8957028)
1996
16
Olivopontocerebellar atrophy: a case report. (7625548)
1995
17
Structural and immunocytochemical features of olivopontocerebellar atrophy caused by the spinocerebellar ataxia type 1 (SCA-1) mutation define a unique phenotype. (8615077)
1995
18
Multiple systems atrophy and nonfamilial olivopontocerebellar atrophy are the same disease. (7755347)
1995
19
The Purkinje cell in olivopontocerebellar atrophy. A Golgi and immunocytochemical study. (7516051)
1994
20
Facial action myoclonus in patients with olivopontocerebellar atrophy. (8196688)
1994
21
Elevated stimulatory and reduced inhibitory G protein alpha subunits in cerebellar cortex of patients with dominantly inherited olivopontocerebellar atrophy. (8473899)
1993
22
Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy. (8272265)
1993
23
Olivopontocerebellar atrophy with retinal degeneration. Fundus characteristics and diagnostic MRI findings. (8233354)
1993
24
Cerebral cortical pathology of sporadic olivopontocerebellar atrophy. (8251013)
1993
25
Progression of retinopathy in olivopontocerebellar atrophy with retinal degeneration. (1580852)
1992
26
Cytoskeletal proteins abnormalities in olivopontocerebellar atrophy]. (1591102)
1992
27
Cytoskeletal protein abnormalities in patients with olivopontocerebellar atrophy--an immunocytochemical and Gallyas silver impregnation study. (1630577)
1992
28
Olivopontocerebellar atrophy of neonatal onset and disialotransferrin developmental deficiency syndrome. (1929507)
1991
29
Striatonigral degeneration, olivopontocerebellar atrophy and "atypical" Pick disease. (1711756)
1991
30
Nocturnal stridor in olivopontocerebellar atrophy. (2267479)
1990
31
Cytoplasmic argyrophilic inclusions in neurons of pontine nuclei in patients with olivopontocerebellar atrophy: immunohistochemical and ultrastructural studies. (2163181)
1990
32
Infantile olivopontocerebellar atrophy with spinal muscular atrophy (infantile OPCA + SMA). (2407400)
1990
33
Oligodendroglial microtubular tangles in olivopontocerebellar atrophy. (1703225)
1990
34
Dominantly inherited olivopontocerebellar atrophy from eastern Cuba. Clinical, neuropathological, and biochemical findings. (2809629)
1989
35
3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: an animal model of olivopontocerebellar atrophy-associated parkinsonism. (2568269)
1989
36
Auditory brainstem response patterns in familial and sporadic olivopontocerebellar atrophy. (3224625)
1988
37
Brain acetylcholinesterase activity is markedly reduced in dominantly-inherited olivopontocerebellar atrophy. (3164041)
1988
38
Neuropathological background of oculomotor disturbances in olivopontocerebellar atrophy with special reference to slow saccade. (3164663)
1988
39
Cognitive deficits in olivopontocerebellar atrophy: implications for the cholinergic hypothesis of Alzheimer's dementia. (3178175)
1988
40
Adrenoleukodystrophy with olivopontocerebellar atrophy-like lesions. (3948452)
1986
41
Enzymatic analysis of individual posterior root ganglion cells in olivopontocerebellar atrophy, amyotrophic lateral sclerosis and Duchenne muscular dystrophy. (4045497)
1985
42
Studies on neurotransmitter markers and neuronal cell density in the cerebellar system in olivopontocerebellar atrophy and cortical cerebellar atrophy. (2868072)
1985
43
Reduction of noradrenaline in cerebellum of patients with olivopontocerebellar atrophy. (6707646)
1984
44
Electromyography and nerve conduction study in autosomal dominant olivopontocerebellar atrophy. (6716108)
1984
45
Clinical features of sporadic (Dejerine-Thomas) olivopontocerebellar atrophy. (6496227)
1984
46
Four biochemically different types of dominantly inherited olivopontocerebellar atrophy. (6149676)
1984
47
The pharmacology of olivopontocerebellar atrophy. (6496225)
1984
48
Olivopontocerebellar atrophy with visual disturbances. An ophthalmologic investigation into four generations. (7443212)
1980
49
Hereditary olivopontocerebellar atrophy. (13523291)
1958
50
Olivopontocerebellar atrophy in a cat. (21010608)
1946

Genetic Variations for Olivopontocerebellar Atrophy

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Expression for genes affiliated with Olivopontocerebellar Atrophy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Olivopontocerebellar Atrophy

Search GEO for disease gene expression data for Olivopontocerebellar Atrophy.

Pathways for genes affiliated with Olivopontocerebellar Atrophy

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49PharmGKB, 37NCBI BioSystems Database, 29KEGG, 4Cell Signaling Technology
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Pathways related to Olivopontocerebellar Atrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1TH, CHAT
29.9SNCA, SLC6A3, TH
3
Hide members
9.9GNAI2, TH, SLC6A3
49.7SLC6A3, ATXN2, SNCA, TH
59.3TH, GLUD1, MAPT, MAP2, ATXN1, SNCA

Compounds for genes affiliated with Olivopontocerebellar Atrophy

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44Novoseek, 11DrugBank, 28IUPHAR, 24HMDB, 59Tocris Bioscience, 49PharmGKB, 2BitterDB
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Compounds related to Olivopontocerebellar Atrophy according to GeneCards/GeneDecks:

(show top 50)    (show all 89)
idCompoundScoreTop Affiliating Genes
1d amphetamine4410.2SLC6A3, TSPO, TH
2ibotenic acid4410.2TH, SLC6A3, CHAT
3thioflavine s4410.2RPS27A, SNCA, MAPT
41-benzyl-1,2,3,4-tetrahydroisoquinoline4410.2SLC6A3, SNCA
5quisqualate44 1111.2MAP2, CHAT, MAPT
6carbidopa44 2811.2SLC6A3, NPPA, TH
71 methyl 4 phenylpyridinium4410.1TH, SLC6A3, SNCA
8apomorphine44 28 1112.1SNCA, SLC6A3, TH, CHAT
9valproate4410.0MAPT, SLC6A3, TH, GLUD1
10spec-t4410.0SLC6A3, MAPT, TSPO, NPPA
114-hydroxynonenal44 2410.9RPS27A, CHAT, SNCA, MAPT
12selegiline44 1110.9TH, SNCA, SLC6A3
13rotenone449.9SLC6A3, RPS27A, TH, SNCA, TSPO
14l-amino acid449.9CHAT, TH, MAP2
15mptp449.9RPS27A, TSPO, SLC6A3, TH, SNCA
166-hydroxydopamine449.9SLC6A3, TH, SNCA, RPS27A, CHAT
17levodopa44 1110.9TSPO, SLC6A3, TH, RPS27A, SNCA
18kainate44 2810.9TSPO, TH, MAPT, MAP2, CHAT
19corticosterone44 59 2411.8CBLN3, MAP2, TSPO, TH
20morphine44 49 28 1112.8TH, NPPA, SLC6A3, TSPO
21sodium dodecylsulfate449.8GLUD1, NPPA, MAPT, SNCA, RPS27A
22glycerol44 11 2411.8MAPT, NPPA, RPS27A, TSPO, GLUD1
23cocaine44 1110.8SLC6A3, MAP2, SNCA, TH, CHAT, TSPO
24catecholamine449.8CHAT, TH, SNCA, NPPA, CBLN3
25methamphetamine44 49 1111.8CHAT, SLC6A3, RPS27A, SNCA, TH, MAP2
26haloperidol44 28 2 49 1113.7CHAT, SLC6A3, TSPO, NPPA, TH, GLUD1
27thioflavin449.7MAPT, SNCA
285-hydroxytryptamine449.7TSPO, TH, CHAT, SLC6A3
29polyacrylamide449.7MAP1B, ATXN7, GLUD1, HAAO, ATXN2
30valine449.7SLC6A3, GLUD1, SNCA, TSPO, RPS27A, MAPT
31nicotine44 49 28 1112.7SLC6A3, TSPO, TH, MAP2, CHAT, MAPT
32silver449.6CHAT, RPS27A, SNCA, MAP1B, MAP2, MAPT
33lactate449.6RPS27A, MAP2, CHAT, GLUD1, TH, MAPT
34glycogen44 2410.5MAPT, MAP2, SNCA, MAP1B, CHAT, RPS27A
35choline44 11 2411.5CHAT, SNCA, MAPT, GLUD1, TH, SLC6A3
36creatinine449.5RPS27A, TSPO, SLC6A3, GLUD1, NPPA, MAPT
37aspartate449.5MAPT, RPS27A, TH, GLUD1, CHAT, SLC6A3
38paraffin449.4SNCA, MAP2, MAP1B, MAPT, TH, RPS27A
39gaba449.3TSPO, GLUD1, TH, RPS27A, CHAT, MAP1B
40acetylcholine44 49 28 11 2413.3SLC6A3, RPS27A, SNCA, CHAT, MAPT, GLUD1
41arginine449.3RPS27A, SLC6A3, GLUD1, MAPT, SNCA, NPPA
42h2o2449.3SLC6A3, TH, GLUD1, MAPT, SNCA, RPS27A
43glutamine449.3TH, TSPO, GLUD1, MAPT, ATXN1, ATXN7
44norepinephrine44 11 2411.3NPPA, SNCA, CHAT, MAP2, CBLN3, TH
45alanine449.2RPS27A, SLC6A3, SNCA, GLUD1, CHAT, MAPT
46testosterone44 59 11 2412.1TSPO, TH, MAPT, MAP2, CHAT, ATXN1
47glutamate449.1SLC6A3, TSPO, RPS27A, GLUD1, TH, MAPT
48dopamine44 28 11 2412.1MAP2, TSPO, SLC6A3, TH, MAPT, RPS27A
49nmda44 2810.1RPS27A, MAPT, GLUD1, TH, MAP1B, CHAT
50estrogen449.0TH, MAPT, RPS27A, MAP2, CHAT, NPPA

GO Terms for genes affiliated with Olivopontocerebellar Atrophy

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16Gene Ontology
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Cellular components related to Olivopontocerebellar Atrophy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear peripheryGO:03439910.0MAPT, MAP2
2microtubule associated complexGO:0058759.9MAPT, MAP2, MAP1B
3axonGO:0304249.6SNCA, CHAT, MAPT, SLC6A3
4neuronal cell bodyGO:0430259.4STRN, CHAT, MAP2, SLC6A3
5cytosolGO:0058298.3RPS27A, GNAI2, HAAO, SNCA, CHAT, MAP1B
6cytoplasmGO:0057378.3GNAI2, STRN, SNCA, ATXN2, ATXN7, ATXN1

Biological processes related to Olivopontocerebellar Atrophy according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of insulin-like growth factor receptor signaling pathwayGO:04356910.2ATXN1, ATXN7
2negative regulation of intracellular transportGO:03238710.1MAPT, MAP1B
3stress granule assemblyGO:03406310.1ATXN2L, ATXN2
4dopamine biosynthetic processGO:04241610.1SLC6A3, TH, SNCA
5neurotransmitter biosynthetic processGO:04213610.1SLC6A3, TH, CHAT
6dendrite developmentGO:01635810.0STRN, CHAT, MAP1B
7cell deathGO:00821910.0ATXN2, ATXN7, ATXN1, SLC6A3
8mitochondrion transport along microtubuleGO:0474979.9MAPT, MAP1B
9axon extensionGO:0486759.9MAPT, MAP1B
10locomotory behaviorGO:0076269.7STRN, TH, SLC6A3
11agingGO:0075689.6TSPO, SLC6A3, SNCA

Molecular functions related to Olivopontocerebellar Atrophy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1dopamine bindingGO:03524010.0SLC6A3, TH
2ferrous iron bindingGO:0081989.8TH, SNCA, HAAO
3microtubule bindingGO:0080179.3MAPT, MAP2, MAP1B, SNCA
4protein bindingGO:0055157.4ATXN2L, ATXN7, ATXN2, SNCA, STRN, GNAI2

Products for genes affiliated with Olivopontocerebellar Atrophy

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Sources for Olivopontocerebellar Atrophy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet