MCID: OPH006
MIFTS: 21

Oophoritis malady

Summaries for Oophoritis

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Sources:
63Wikipedia, 32MalaCards
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Wikipedia:63 Oophoritis is an inflammation of the ovaries. more...

MalaCards: Oophoritis is related to infertility and salpingo-oophoritis. An important gene associated with Oophoritis is AMH (anti-Mullerian hormone), and among its related pathways are Primary immunodeficiency and Ovarian Infertility Genes. Affiliated tissues include ovary, and related mouse phenotypes are endocrine/exocrine gland and reproductive system.

Aliases & Classifications for Oophoritis

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Sources:
10DISEASES, 60UMLS
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Aliases & Descriptions:

oophoritis 10 60


Related Diseases for Oophoritis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Oophoritis:



Diseases related to oophoritis

Clinical Features for Oophoritis

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Drugs & Therapeutics for Oophoritis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Oophoritis

Drug clinical trials:

Search ClinicalTrials for Oophoritis

Search NIH Clinical Center for Oophoritis

Search CenterWatch for Oophoritis

Genetic Tests for Oophoritis

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Anatomical Context for Oophoritis

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32MalaCards
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MalaCards organs/tissues related to Oophoritis:

32
Ovary

Animal Models for Oophoritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Oophoritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.0NOBOX, PZP, ZP2, ZP1, ZP3, AMH
2MP:00053897.2NOBOX, AMH, NLRP5, ZP3, ZP1, ZP2

Publications for Oophoritis

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Genetic Variations for Oophoritis

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Expression for genes affiliated with Oophoritis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Oophoritis

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Pathways for genes affiliated with Oophoritis

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Sources:
29KEGG, 37NCBI BioSystems Database, 53Reactome
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Pathways related to Oophoritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8CD4, IGLL1
29.4ZP2, ZP3
3
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8.5ZP4, ZP2, ZP1, ZP3

Compounds for genes affiliated with Oophoritis

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GO Terms for genes affiliated with Oophoritis

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16Gene Ontology
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Cellular components related to Oophoritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1multivesicular bodyGO:0057719.1ZP3, ZP2
2extracellular spaceGO:0056158.9PZP, ZP3, C8G, AMH
3secretory granuleGO:0301418.8ZP2, ZP1, ZP3
4proteinaceous extracellular matrixGO:0055788.5ZP3, ZP1, ZP2, ZP4
5extracellular regionGO:0055767.3IGLL1, AMH, C8G, ZP3, ZP1, ZP2

Biological processes related to Oophoritis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of humoral immune responseGO:0029229.5ZP4, ZP3
2negative regulation of binding of sperm to zona pellucidaGO:20003609.5ZP4, ZP3
3positive regulation of acrosome reactionGO:20003449.4ZP3, ZP4
4positive regulation of T cell proliferationGO:0421029.4ZP4, ZP3
5manganese ion transportGO:0068289.3ZP2, ZP3
6positive regulation of protein kinase activityGO:0458609.2ZP3, ZP4, CD4
7protein kinase C signaling cascadeGO:0705289.1ZP4, ZP3
8multicellular organism reproductionGO:0325048.7ZP4, ZP2, ZP1, ZP3
9binding of sperm to zona pellucidaGO:0073398.7ZP3, ZP1, ZP2, ZP4
10single fertilizationGO:0073388.6ZP4, ZP2, ZP1, ZP3

Molecular functions related to Oophoritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:0150269.7CD4, ZP2
2acrosin bindingGO:0321908.7ZP4, ZP2, ZP3

Products for genes affiliated with Oophoritis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Oophoritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet