MCID: OPS001
MIFTS: 36

Opisthorchiasis malady

Categories: Rare diseases, Infectious diseases, Liver diseases

Aliases & Classifications for Opisthorchiasis

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Aliases & Descriptions for Opisthorchiasis:

Name: Opisthorchiasis 11 48 50 39 13 68
Infection Due to Cat Liver Fluke 48
 
Infection Due to Opisthorchis 48
Infection by Opisthorchis 11

Classifications:



External Ids:

Disease Ontology11 DOID:13768
ICD1030 B66.0
SNOMED-CT62 1059007, 187124006
ICD9CM32 121.0
MeSH39 D009889

Summaries for Opisthorchiasis

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Disease Ontology:11 A parasitic helminthiasis infectious disease that involves parasitic infection of the liver, pancreas and gall bladder by Opisthorchis viverrini or Opisthorchis felineus. The symptoms include dyspepsia, abdominal pain, diarrhea, constipation, hepatomegaly, cholangitis, cholecystitis, and chlolangiocarcinoma.

MalaCards based summary: Opisthorchiasis, also known as infection due to cat liver fluke, is related to acute lymphocytic leukemia and osteogenesis imperfecta, type x. An important gene associated with Opisthorchiasis is MFGE8 (Milk Fat Globule-EGF Factor 8 Protein), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and Cytokines and Inflammatory Response. The drugs albendazole and praziquantel have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and testes.

Wikipedia:71 Opisthorchiasis is a parasitic disease caused by species in the genus Opisthorchis (specifically,... more...

Related Diseases for Opisthorchiasis

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Diseases related to Opisthorchiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 103)
idRelated DiseaseScoreTop Affiliating Genes
1acute lymphocytic leukemia10.5AFP, GPT
2osteogenesis imperfecta, type x10.3CXCL8, IL6R
3basidiobolomycosis10.3CXCL8, IL4
4anterior dislocation of lens10.3CXCL8, IL4
5lupus erythematosus10.3GPT, IL1B
6hepatic coma10.3AFP, GPT
7benign fibrous mesothelioma10.3CXCL8, IL4
8cat-scratch disease10.3GPT, IL1B
9buphthalmos10.2CXCL8, IL4
10ileitis10.2IL1B, IL4
11keloids10.2IL1B, IL6R
12vaginitis10.2CXCL8, IL4
13geotrichosis10.2CXCL8, IL4
14dentin caries10.2CXCL8, IL4
15african histoplasmosis10.2IL1B, IL4
16scn8a encephalopathy10.2IL1B, IL4
17philophthalmiasis10.2IL1B, IL4
18senile cataract10.2IL1B, IL4
19oesophagostomiasis10.2IL1B, IL4
20bartonellosis10.2IL1B, IL4
21esophagus melanoma10.1CXCL8, IL4
22corneal deposit10.1CXCL8, IL1B
23tarsal tunnel syndrome10.1CXCL8, IL1B
24histiocytoid hemangioma10.1IL1B, IL4
25contact blepharoconjunctivitis10.1CXCL8, IL1B
26infancy electroclinical syndrome10.1CXCL8, IL1B
27benign lymphoepithelial lesion of salivary gland10.1IL1B, IL4
28skin disease10.1CXCL8, IL1B
29subglottis neoplasm10.1CXCL8, IL1B
30paraphimosis10.1CXCL8, IL1B
31clonorchiasis10.1
32qualitative platelet defect10.1CXCL8, IL1B
33inflammatory spondylopathy10.1CXCL8, IL1B
34burns10.1CXCL8, IL1B
35ocular cancer10.1CXCL8, IL1B
36pseudoretinitis pigmentosa10.1CXCL8, IL1B
37paraneoplastic polyneuropathy10.1CXCL8, IL1B
38oral candidiasis10.1CXCL8, IL1B
39inner ear cancer10.1CXCL8, IL1B
40accessory nerve disease10.1CXCL8, IL1B
41biliary tract disease10.1CXCL8, IL4
42extrahepatic cholestasis10.1CXCL8, GPT
43tibialis tendinitis10.1CXCL8, IL1B
44retinal vascular disease10.0CXCL8, IL4, IL6R
45intracortical osteogenic sarcoma10.0CXCL8, IL1B
46hepatitis10.0
47kidney angiomyolipoma10.0CXCL8, IL1B
48secondary lacrimal atrophy10.0IL1B, IL4
49serous labyrinthitis10.0CXCL8, IL1B
50pediatric supratentorial ependymoma10.0CXCL8, IL1B

Graphical network of the top 20 diseases related to Opisthorchiasis:



Diseases related to opisthorchiasis

Symptoms & Phenotypes for Opisthorchiasis

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Drugs & Therapeutics for Opisthorchiasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Opisthorchiasis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: opisthorchiasis

Genetic Tests for Opisthorchiasis

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Anatomical Context for Opisthorchiasis

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MalaCards organs/tissues related to Opisthorchiasis:

36
Liver, Pancreas, Testes

Publications for Opisthorchiasis

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Articles related to Opisthorchiasis:

(show top 50)    (show all 166)
idTitleAuthorsYear
1
Epstein-Barr Virus Infection and Opisthorchiasis: A Story of Cholangiocarcinoma in the Highly Endemic Area. (27482325)
2016
2
Andrographolide Ameliorates Beta-Naphthoflavone-Induced CYP1A Enzyme Activity and Lipid Peroxidation in Hamsters with Acute Opisthorchiasis. (26817235)
2016
3
Efficacious and safe dose of praziquantel for the successful treatment of feline reservoir hosts with opisthorchiasis. (27576001)
2016
4
Ultrasonographic features of hepatobiliary in opisthorchiasis. (27956092)
2016
5
Opisthorchiasis in Western Siberia: Epidemiology and distribution in human, fish, snail, and animal populations. (27939972)
2016
6
Development of an ELISA using anti-idiotypic antibody for diagnosis of opisthorchiasis. (27507639)
2016
7
Chicken IgY-based coproantigen capture ELISA for diagnosis of human opisthorchiasis. (27140305)
2016
8
The Lawa model: A sustainable, integrated opisthorchiasis control program using the EcoHealth approach in the Lawa Lake region of Thailand. (27890720)
2016
9
Co-infections with liver fluke and Helicobacter species: A paradigm change in pathogenesis of opisthorchiasis and cholangiocarcinoma? (27919744)
2016
10
Community-Based Health Education and Communication Model Development for Opisthorchiasis Prevention in a High Risk Area, Khon Kaen Province, Thailand. (26625799)
2015
11
Cholangiocarcinoma and opisthorchiasis in Northeast Thailand: raw fish intake may not be the sole cause. (26108023)
2015
12
Immunodiagnosis of opisthorchiasis using parasite cathepsin F. (26344868)
2015
13
Comparative evaluation of Strongyloides ratti and S. stercoralis larval antigen for diagnosis of strongyloidiasis in an endemic area of opisthorchiasis. (25877389)
2015
14
Opisthorchiasis in infant remains from the medieval Zeleniy Yar burial ground of XII-XIII centuries AD. (26602874)
2015
15
Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma. (26312563)
2015
16
Anthelmintic, anti-inflammatory and antioxidant effects of Garcinia mangostana extract in hamster opisthorchiasis. (25836376)
2015
17
Advances in the Diagnosis of Human Opisthorchiasis: Development of Opisthorchis viverrini Antigen Detection in Urine. (26485024)
2015
18
Opisthorchiasis: an overlooked danger. (25836334)
2015
19
An interleukin-6 receptor polymorphism is associated with opisthorchiasis-linked cholangiocarcinoma risk in Thailand. (25041016)
2014
20
Toward integrated opisthorchiasis control in Northeast Thailand: The Lawa project. (25102053)
2014
21
Infectious Diseases and Tropical Disease Pathology: SY16-3 OPISTHORCHIASIS: FROM PATHOGENESIS TO CONTROL. (25188119)
2014
22
Milk fat globule epidermal growth factor 8 serves a novel biomarker of opisthorchiasis-associated cholangiocarcinoma. (24122204)
2013
23
Microproteinuria during Opisthorchis viverrini infection: a biomarker for advanced renal and hepatobiliary pathologies from chronic opisthorchiasis. (23717698)
2013
24
Diagnosis of early infection and post chemotherapeutic treatment by copro-DNA detection in experimental opisthorchiasis. (23052766)
2013
25
Development of a community-based approach to opisthorchiasis control. (24377646)
2013
26
Correction: Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis. (24349600)
2013
27
High prevalence of haplorchiasis in Nan and Lampang provinces, Thailand, proven by adult worm recovery from suspected opisthorchiasis cases. (24516289)
2013
28
Oxidized alpha-1 antitrypsin as a predictive risk marker of opisthorchiasis-associated cholangiocarcinoma. (23188705)
2013
29
Increase of exostosin 1 in plasma as a potential biomarker for opisthorchiasis-associated cholangiocarcinoma. (24018821)
2013
30
Does a combination of opisthorchiasis and ethyl alcohol consumption enhance early cholangiofibrosis, the risk of cholangiocarcinoma? (23807659)
2013
31
Improved performance and quantitative detection of copro-antigens by a monoclonal antibody based ELISA to diagnose human opisthorchiasis. (24055716)
2013
32
Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis. (21704727)
2012
33
Anti-inflammatory effect of prednisolone on the growth of human liver fluke in experimental opisthorchiasis. (22186974)
2012
34
Discovery of human opisthorchiasis: a mysterious history. (21867771)
2012
35
High prevalence of Opisthorchis viverrini infection in reservoir hosts in four districts of Khon Kaen Province, an opisthorchiasis endemic area of Thailand. (21843654)
2012
36
The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. (21893213)
2012
37
Oxidative and nitrative DNA damage: key events in opisthorchiasis-induced carcinogenesis. (21704729)
2012
38
A large outbreak of Opisthorchis felineus in Italy suggests that opisthorchiasis develops as a febrile eosinophilic syndrome with cholestasis rather than a hepatitis-like syndrome. (21938537)
2012
39
Increased expression of TLR-2, COX-2, and SOD-2 genes in the peripheral blood leukocytes of opisthorchiasis patients induced by Opisthorchis viverrini antigen. (22160279)
2012
40
Expression profiles of oncomir miR-21 and tumor suppressor let-7a in the progression of opisthorchiasis-associated cholangiocarcinoma. (23480766)
2012
41
Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis. (21704728)
2012
42
Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: a potential molecular marker for tumor metastasis. (21763455)
2012
43
Anti-inflammatory, antioxidant and hepatoprotective effects of Thunbergia laurifolia Linn. on experimental opisthorchiasis. (22327320)
2012
44
Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. (20655862)
2011
45
Detection of salivary antibodies to crude antigens of Opisthorchis viverrini in opisthorchiasis and cholangiocarcinoma patients. (20446100)
2011
46
Histopathological diagnosis of opisthorchiasis in an immigrant. (20889856)
2010
47
Opisthorchis viverrini: evaluation of 28 kDa glutathione S-transferase as diagnostic tool in human opisthorchiasis. (20096257)
2010
48
Iso-electricfocusing of Bithynia snail antigens for IgG- and IgG(1-4)-ELISA detection of human opisthorchiasis. (21073055)
2010
49
Dynamics of pro-and anti-inflammatory cytokines at patients with combination of chronic opisthorchiasis with Helicobacter pylori-associated gastritis]. (19551959)
2009
50
Turmeric reduces inflammatory cells in hamster opisthorchiasis. (19633869)
2009

Variations for Opisthorchiasis

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Expression for genes affiliated with Opisthorchiasis

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Search GEO for disease gene expression data for Opisthorchiasis.

Pathways for genes affiliated with Opisthorchiasis

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GO Terms for genes affiliated with Opisthorchiasis

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Cellular components related to Opisthorchiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056156.6AFP, CTSF, CXCL8, GPT, IL1B, IL4

Biological processes related to Opisthorchiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.9IL1B, IL4
2positive regulation of chemokine biosynthetic processGO:00450809.9IL1B, IL4
3positive regulation of neutrophil chemotaxisGO:00900239.7CXCL8, IL1B
4positive regulation of phagocytosisGO:00507669.6IL1B, MFGE8

Sources for Opisthorchiasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet