MCID: OPS001
MIFTS: 37

Opisthorchiasis malady

Categories: Rare diseases, Infectious diseases, Liver diseases

Aliases & Classifications for Opisthorchiasis

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Aliases & Descriptions for Opisthorchiasis:

Name: Opisthorchiasis 11 46 13 48 37 66
Infection Due to Cat Liver Fluke 46
 
Infection Due to Opisthorchis 46
Infection by Opisthorchis 11

Classifications:



External Ids:

Disease Ontology11 DOID:13768
ICD1028 B66.0
SNOMED-CT60 1059007, 187124006
ICD9CM30 121.0
MeSH37 D009889

Summaries for Opisthorchiasis

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Disease Ontology:11 A parasitic helminthiasis infectious disease that involves parasitic infection of the liver, pancreas and gall bladder by opisthorchis viverrini or opisthorchis felineus. the symptoms include dyspepsia, abdominal pain, diarrhea, constipation, hepatomegaly, cholangitis, cholecystitis, and chlolangiocarcinoma.

MalaCards based summary: Opisthorchiasis, also known as infection due to cat liver fluke, is related to acute lymphocytic leukemia and lupus erythematosus. An important gene associated with Opisthorchiasis is MFGE8 (Milk Fat Globule-EGF Factor 8 Protein), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and Cytokines and Inflammatory Response. The drugs albendazole and praziquantel have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and testes.

Wikipedia:69 Opisthorchiasis is a parasitic disease caused by species in the genus Opisthorchis (specifically,... more...

Related Diseases for Opisthorchiasis

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Diseases related to Opisthorchiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 106)
idRelated DiseaseScoreTop Affiliating Genes
1acute lymphocytic leukemia10.6AFP, GPT
2lupus erythematosus10.5GPT, IL1B
3cat-scratch disease10.4GPT, IL1B
4hepatic coma10.4AFP, GPT
5keloids10.4IL1B, IL6R
6ileitis10.3IL1B, IL4
7osteogenesis imperfecta, type x10.3CXCL8, IL6R
8african histoplasmosis10.3IL1B, IL4
9scn8a encephalopathy10.3IL1B, IL4
10philophthalmiasis10.3IL1B, IL4
11senile cataract10.3IL1B, IL4
12oesophagostomiasis10.3IL1B, IL4
13bartonellosis10.2IL1B, IL4
14basidiobolomycosis10.2CXCL8, IL4
15clonorchiasis10.2
16anterior dislocation of lens10.2CXCL8, IL4
17histiocytoid hemangioma10.2IL1B, IL4
18benign lymphoepithelial lesion of salivary gland10.2IL1B, IL4
19benign fibrous mesothelioma10.2CXCL8, IL4
20corneal deposit10.2CXCL8, IL1B
21tarsal tunnel syndrome10.2CXCL8, IL1B
22hepatitis10.2
23contact blepharoconjunctivitis10.2CXCL8, IL1B
24infancy electroclinical syndrome10.2CXCL8, IL1B
25skin disease10.2CXCL8, IL1B
26subglottis neoplasm10.2CXCL8, IL1B
27amyotrophic lateral sclerosis type 410.2CXCL8, IL1B
28paraphimosis10.2CXCL8, IL1B
29qualitative platelet defect10.2CXCL8, IL1B
30inflammatory spondylopathy10.1CXCL8, IL1B
31buphthalmos10.1CXCL8, IL4
32burns10.1CXCL8, IL1B
33ocular cancer10.1CXCL8, IL1B
34pseudoretinitis pigmentosa10.1CXCL8, IL1B
35paraneoplastic polyneuropathy10.1CXCL8, IL1B
36vaginitis10.1CXCL8, IL4
37oral candidiasis10.1CXCL8, IL1B
38hidradenitis suppurativa10.1CXCL8, IL1B
39inner ear cancer10.1CXCL8, IL1B
40geotrichosis10.1CXCL8, IL4
41secondary lacrimal atrophy10.1IL1B, IL4
42accessory nerve disease10.1CXCL8, IL1B
43radioulnar synostosis retinal pigment abnormalities10.1CXCL8, IL1B
44dentin caries10.1CXCL8, IL4
45tibialis tendinitis10.1CXCL8, IL1B
46intracortical osteogenic sarcoma10.1CXCL8, IL1B
47wissler's syndrome10.1IL1B, IL4
48kidney angiomyolipoma10.1CXCL8, IL1B
49esophagus melanoma10.1CXCL8, IL4
50serous labyrinthitis10.0CXCL8, IL1B

Graphical network of the top 20 diseases related to Opisthorchiasis:



Diseases related to opisthorchiasis

Symptoms for Opisthorchiasis

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Drugs & Therapeutics for Opisthorchiasis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Opisthorchiasis

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: opisthorchiasis

Genetic Tests for Opisthorchiasis

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Anatomical Context for Opisthorchiasis

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MalaCards organs/tissues related to Opisthorchiasis:

34
Liver, Pancreas, Testes

Animal Models for Opisthorchiasis or affiliated genes

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Publications for Opisthorchiasis

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Articles related to Opisthorchiasis:

(show top 50)    (show all 162)
idTitleAuthorsYear
1
Epstein-Barr Virus Infection and Opisthorchiasis: A Story of Cholangiocarcinoma in the Highly Endemic Area. (27482325)
2016
2
Andrographolide Ameliorates Beta-Naphthoflavone-Induced CYP1A Enzyme Activity and Lipid Peroxidation in Hamsters with Acute Opisthorchiasis. (26817235)
2016
3
Efficacious and safe dose of praziquantel for the successful treatment of feline reservoir hosts with opisthorchiasis. (27576001)
2016
4
Community-Based Health Education and Communication Model Development for Opisthorchiasis Prevention in a High Risk Area, Khon Kaen Province, Thailand. (26625799)
2015
5
Cholangiocarcinoma and opisthorchiasis in Northeast Thailand: raw fish intake may not be the sole cause. (26108023)
2015
6
Milk fat globule epidermal growth factor 8 serves a novel biomarker of opisthorchiasis-associated cholangiocarcinoma. (24122204)
2013
7
Microproteinuria during Opisthorchis viverrini infection: a biomarker for advanced renal and hepatobiliary pathologies from chronic opisthorchiasis. (23717698)
2013
8
Diagnosis of early infection and post chemotherapeutic treatment by copro-DNA detection in experimental opisthorchiasis. (23052766)
2013
9
Development of a community-based approach to opisthorchiasis control. (24377646)
2013
10
Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis. (21704727)
2012
11
Anti-inflammatory effect of prednisolone on the growth of human liver fluke in experimental opisthorchiasis. (22186974)
2012
12
Discovery of human opisthorchiasis: a mysterious history. (21867771)
2012
13
High prevalence of Opisthorchis viverrini infection in reservoir hosts in four districts of Khon Kaen Province, an opisthorchiasis endemic area of Thailand. (21843654)
2012
14
Histopathological diagnosis of opisthorchiasis in an immigrant. (20889856)
2010
15
Opisthorchis viverrini: evaluation of 28 kDa glutathione S-transferase as diagnostic tool in human opisthorchiasis. (20096257)
2010
16
Iso-electricfocusing of Bithynia snail antigens for IgG- and IgG(1-4)-ELISA detection of human opisthorchiasis. (21073055)
2010
17
Dynamics of pro-and anti-inflammatory cytokines at patients with combination of chronic opisthorchiasis with Helicobacter pylori-associated gastritis]. (19551959)
2009
18
Turmeric reduces inflammatory cells in hamster opisthorchiasis. (19633869)
2009
19
Effect of curcumin on pathogenesis of hamster-opisthorchiasis through apoptosis-related gene expression. (20578454)
2009
20
Local perceptions and practices in regard to opisthorchiasis in two villages in Lao PDR. (18567439)
2008
21
Opisthorchiasis in Thailand: review and current status. (18416453)
2008
22
Apoptosis-related gene expression in hamster opisthorchiasis post praziquantel treatment. (18058134)
2008
23
Molecular genetic approaches in parasitology (in case of opisthorchiasis)]. (17663039)
2007
24
Analysis of a complex of biochemical parameters of hepatic functions in opisthorchiasis]. (16445232)
2005
25
Opisthorchis viverrini and opisthorchiasis: The 21st Century review. Proceedings of the Congress of Opisthorchiasis and Cholangiocarcinoma. May 28-30, 2002. Khon Kaen, Thailand. (14763464)
2003
26
Impact of anthelminthic therapy for opisthorchiasis on the biochemical parameters of hepatic function]. (12886584)
2003
27
Clinical and immune peculiarities of pseudotuberculous polyarthritis against a background of chronic opisthorchiasis. (9566679)
1998
28
Place of surgery in opisthorchiasis associated cholangiocarcinoma. (9656356)
1997
29
Serum antibody responses in opisthorchiasis. (8550296)
1995
30
Serum antibody response to Opisthorchis viverrini antigen as a marker for opisthorchiasis-associated cholangiocarcinoma. (7570848)
1994
31
Changes in serum antibodies to Opisthorchis viverrini in humans and hamsters following treatment of opisthorchiasis. (7872997)
1994
32
The serum immunoglobulin E level and the endocrine activity of the stomach, duodenum and pancreas after recovery from opisthorchiasis]. (2233534)
1990
33
Fecal egg output in relation to worm burden and clinical features in human opisthorchiasis. (2237595)
1990
34
Effect of praziquantel treatment on antibody levels and lymphoproliferative responses in patients with opisthorchiasis. (3406800)
1988
35
Incidence of bacteremia in patients with opisthorchiasis during recurrent cholangitis. (3227401)
1988
36
Public health aspects of opisthorchiasis in Thailand. (6542380)
1984
37
Computed tomography in opisthorchiasis. (6529907)
1984
38
Infection and re-infection rates of opisthorchiasis in the water resource development area of Nam Pong project, Khon Kaen Province, northeast Thailand. (6532334)
1984
39
Treatment of Opisthorchiasis viverrini in hamsters with albendazole. (6523174)
1984
40
Clonorchiasis/opisthorchiasis in South Carolina. (6572766)
1983
41
Increased efficacy of liposomes-encapsulated praziquantel in treatment of opisthorchiasis in hamsters. (6673127)
1983
42
Morbidity in relation to intensity of infection in Opisthorchiasis viverrini: study of a community in Khon Kaen, Thailand. (6983303)
1982
43
Studies on the chemotherapy of human opisthorchiasis: II. Clinical trial of niclofolan. (7020093)
1981
44
Field trial of praziquantel in human opisthorchiasis in Thailand. (7344110)
1981
45
Polyacrylamide gel electrophoresis of human serum in subclinical opisthorchiasis. (4432102)
1974
46
A clinical trial of oral dehydroemetine in opisthorchiasis. (4617315)
1974
47
Serum vitamin B 12 level in patients with amoebic liver abscess, opisthorchiasis and hookworm infections. (5112336)
1971
48
Pathology of liver and pancreas in opisthorchiasis noverca in dogs and pigs. (5103963)
1971
49
Opisthorchiasis with pulmonary involvement. (13738024)
1961
50
Retention cyst of liver caused by opisthorchiasis associated with carcinoma; case report. (14361385)
1955

Variations for Opisthorchiasis

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Expression for genes affiliated with Opisthorchiasis

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Search GEO for disease gene expression data for Opisthorchiasis.

Pathways for genes affiliated with Opisthorchiasis

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GO Terms for genes affiliated with Opisthorchiasis

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Cellular components related to Opisthorchiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056156.7AFP, CTSF, CXCL8, GPT, IL1B, IL4

Biological processes related to Opisthorchiasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of chemokine biosynthetic processGO:00450809.9IL1B, IL4
2positive regulation of phagocytosisGO:00507669.7IL1B, MFGE8
3extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.5IL1B, IL4
4positive regulation of neutrophil chemotaxisGO:00900239.2CXCL8, IL1B

Sources for Opisthorchiasis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet