MCID: OPT006
MIFTS: 35

Optic Nerve Disease malady

Eye diseases, Neuronal diseases categories

Summaries for Optic Nerve Disease

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63Wikipedia, 32MalaCards
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Wikipedia:63 The optic nerve, also known as cranial nerve II, transmits visual information from the retina to the... more...

MalaCards: Optic Nerve Disease, also known as optic neuropathy, is related to neuropathy and ischemic optic neuropathy. An important gene associated with Optic Nerve Disease is OPTN (optineurin). Affiliated tissues include retina, eye and testes.

Aliases & Classifications for Optic Nerve Disease

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8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases, Neuronal diseases


Aliases & Descriptions:

optic nerve disease 8
optic neuropathy 8 44
disorder of the second nerve 8
disorder of the optic nerve 60
disorder of optic nerve 8
optic nerve disorder 8


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Disease Ontology8 DOID:1891
NCIt39 C79698
MeSH34 D009901
ICD1025 H47.0

Related Diseases for Optic Nerve Disease

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Optic Nerve Disease:



Diseases related to optic nerve disease

Clinical Features for Optic Nerve Disease

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Drugs & Therapeutics for Optic Nerve Disease

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Optic Nerve Disease

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Anatomical Context for Optic Nerve Disease

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32MalaCards
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MalaCards organs/tissues related to Optic Nerve Disease:

32
Retina, Eye, Testes, Spinal cord, Brain, Adrenal gland

Animal Models for Optic Nerve Disease or affiliated genes

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Publications for Optic Nerve Disease

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50PubMed
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Articles related to Optic Nerve Disease:

(show top 50)    (show all 76)
idTitleAuthorsYear
1
Bilateral orbital and optic nerve endoscopic endonasal decompression for nonspecific inflammatory orbital disease: case report. (23042140)
2013
2
Intracranial optic nerve enlargement in infantile Krabbe disease. (22585439)
2012
3
Electrical stimulation--a therapeutic strategy for retinal and optic nerve disease? (22282217)
2012
4
Optic nerve disease and axon pathophysiology. (23206593)
2012
5
Optic nerve enlargement in Krabbe disease: a pathophysiologic and clinical perspective. (21285037)
2011
6
Optic nerve enlargement and leukodystrophy: an unusual finding of the infantile form of Krabbe disease. (21049202)
2010
7
Animal models of human retinal and optic nerve diseases analysed using electroretinography]. (20387538)
2010
8
Electrodiagnostic assessment in optic nerve disease. (19155758)
2009
9
Optic nerve enhancement in Coats disease with secondary glaucoma. (19541272)
2009
10
The effect of generalized discriminate analysis (GDA) to the classification of optic nerve disease from VEP signals. (17709102)
2008
11
Ensemble adaptive network-based fuzzy inference system with weighted arithmetical mean and application to diagnosis of optic nerve disease from visual-evoked potential signals. (18468871)
2008
12
Optic nerve and chiasm enlargement in a case of infantile Krabbe disease: quantitative comparison with 26 age-matched controls. (18438656)
2008
13
Neural network-based diagnosing for optic nerve disease from visual-evoked potential. (17918693)
2007
14
Visual deficits in a mouse model of Batten disease are the result of optic nerve degeneration and loss of dorsal lateral geniculate thalamic neurons. (16412658)
2006
15
The role of the Met98Lys optineurin variant in inherited optic nerve diseases. (16885188)
2006
16
Image analysis of optic nerve disease. (15534606)
2004
17
Electrophysiological assessment of optic nerve disease. (15534599)
2004
18
Ultrastructural changes in the optic nerves of rodents with experimental Creutzfeldt-Jakob Disease (CJD), Gerstmann-StrAoussler-Scheinker disease (GSS) or scrapie. (12921728)
2003
19
Visual dysfunction in retinal and optic nerve disease. (12916487)
2003
20
MRI to differentiate causes of optic nerve disease. (13129905)
2003
21
Retinal masqueraders of optic nerve disease. (11370571)
2001
22
Optic nerve blindness due to paranasal sinus disease. (10420111)
1999
23
Acquired mitochondrial impairment as a cause of optic nerve disease. (10360310)
1998
24
Risk factors for optic nerve disease in communities mesoendemic for savannah onchocerciasis, Kaduna State, Nigeria. (9018306)
1997
25
Orbital disease, optic nerve and chiasm. (9099523)
1997
26
Localisation of a 10q breakpoint within the PAX2 gene in a patient with a de novo t(10;13) translocation and optic nerve coloboma-renal disease. (9132492)
1997
27
Successful surgical removal of an asymptomatic optic nerve hemangioblastoma in von Hippel-Lindau disease. (9038433)
1997
28
Establishing a reliable visual function test and applying it to screening optic nerve disease in onchocercal communities. (8735773)
1996
29
Spatial tuning loss of pattern reversal visual evoked response in optic nerve disease. (8739685)
1996
30
Flash visual evoked potential (VEP) in amblyopia and optic nerve disease. (8532302)
1995
31
Nutrition and optic nerve disease. (10159744)
1995
32
Cyclosporine effects on optic nerve and retinal vasculitis in BehAset's disease. (1425128)
1992
33
Pattern electroretinogram peak times as a clinical means of discriminating retinal from optic nerve disease. (2776633)
1989
34
The spectrum of optic nerve disease in human immunodeficiency virus infection. (2539020)
1989
35
The differential effect of optic nerve disease on pattern and focal electroretinograms. (3665701)
1987
36
Standardized A-scan echography in optic nerve disease. (3307721)
1987
37
The pattern electroretinogram in patients with optic nerve disease. (3956359)
1986
38
Stereoacuity in patients with optic nerve disease. (3977672)
1985
39
Brightness-sense and optic nerve disease. (3977673)
1985
40
Edge-light pupil cycle time and optic nerve disease. (6660715)
1983
41
Vitreous fluorophotometry in optic nerve disease. (7104274)
1982
42
Auditory evoked phosphenes in optic nerve disease. (7062073)
1982
43
Visual evoked potential and pupillary signs. A comparison in optic nerve disease. (7138329)
1982
44
Multiple regression analysis of diagnostic predictors in optic nerve disease. (7225960)
1981
45
Optic nerve hypoplasia: a benign entity simulating acquired neurological disease. (553389)
1979
46
Neurophysiological investigation in optic nerve disease: combined assessment of the visual evoked response and electroretinogram. (646982)
1978
47
Optic nerve glioma and phaeochromocytoma associated with von Recklinghausen's disease: A case report. (403930)
1977
48
Visually evoked responses in optic nerve disease. (1071915)
1976
49
Pathogenesis of glaucomatous optic nerve disease. (1246811)
1975
50
PSEUDO-ARGYLL ROBERTSON PUPILS IN OPTIC NERVE DISEASE. (14189742)
1964

Genetic Variations for Optic Nerve Disease

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Expression for genes affiliated with Optic Nerve Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Optic Nerve Disease

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Pathways for genes affiliated with Optic Nerve Disease

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Compounds for genes affiliated with Optic Nerve Disease

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GO Terms for genes affiliated with Optic Nerve Disease

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16Gene Ontology
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Cellular components related to Optic Nerve Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi membraneGO:0001399.1GRM6, OPTN

Products for genes affiliated with Optic Nerve Disease

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  • Antibodies
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Sources for Optic Nerve Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet