MCID: OPT006
MIFTS: 35

Optic Nerve Disease malady

Eye diseases, Neuronal diseases categories

Summaries for Optic Nerve Disease

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 The optic nerve, also known as cranial nerve II, transmits visual information from the retina to the... more...

MalaCards: Optic Nerve Disease, also known as optic neuropathy, is related to neuropathy and ischemic optic neuropathy. An important gene associated with Optic Nerve Disease is OPTN (optineurin). Affiliated tissues include retina, eye and testes.

Aliases & Classifications for Optic Nerve Disease

About this section
Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases, Neuronal diseases


Aliases & Descriptions:

optic nerve disease 8
optic neuropathy 8 44
disorder of the second nerve 8
disorder of the optic nerve 60
disorder of optic nerve 8
optic nerve disorder 8


External Ids:

Disease Ontology8 DOID:1891
NCIt39 C79698
MeSH34 D009901
ICD1025 H47.0

Related Diseases for Optic Nerve Disease

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Optic Nerve Disease:



Diseases related to optic nerve disease

Clinical Features for Optic Nerve Disease

About this section

Drugs & Therapeutics for Optic Nerve Disease

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Optic Nerve Disease

Drug clinical trials:

Search ClinicalTrials for Optic Nerve Disease

Search NIH Clinical Center for Optic Nerve Disease

Search CenterWatch for Optic Nerve Disease

Genetic Tests for Optic Nerve Disease

About this section

Anatomical Context for Optic Nerve Disease

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Optic Nerve Disease:

32
Retina, Eye, Testes, Brain, Spinal cord, Adrenal gland

Animal Models for Optic Nerve Disease or affiliated genes

About this section

Publications for Optic Nerve Disease

About this section
Sources:
50PubMed
See all sources

Articles related to Optic Nerve Disease:

(show top 50)    (show all 76)
idTitleAuthorsYear
1
Bilateral orbital and optic nerve endoscopic endonasal decompression for nonspecific inflammatory orbital disease: case report. (23042140)
2013
2
Detection of disease-associated prion protein in the optic nerve and the adrenal gland of cattle with bovine spongiform encephalopathy by using highly sensitive immunolabeling procedures. (22260993)
2012
3
Intracranial optic nerve enlargement in infantile Krabbe disease. (22585439)
2012
4
Electrical stimulation--a therapeutic strategy for retinal and optic nerve disease? (22282217)
2012
5
Optic nerve involvement in Lyme disease. (23047166)
2012
6
Optic nerve disease and axon pathophysiology. (23206593)
2012
7
Detection of optic nerve disease in retinoblastoma by use of spectral domain optical coherence tomography. (23084390)
2012
8
Positional ocular flutter and thickened optic nerves as sentinel signs of Krabbe disease. (22153408)
2011
9
Optic nerve enlargement and leukodystrophy: an unusual finding of the infantile form of Krabbe disease. (21049202)
2010
10
Electrodiagnostic assessment in optic nerve disease. (19155758)
2009
11
Optic nerve enhancement in Coats disease with secondary glaucoma. (19541272)
2009
12
Utilization of Discretization method on the diagnosis of optic nerve disease. (18571280)
2008
13
The effect of generalized discriminate analysis (GDA) to the classification of optic nerve disease from VEP signals. (17709102)
2008
14
Optic nerve and chiasm enlargement in a case of infantile Krabbe disease: quantitative comparison with 26 age-matched controls. (18438656)
2008
15
Classification of macular and optic nerve disease by principal component analysis. (17046736)
2007
16
Optic nerve and spinal cord manifestations of malignant atrophic papulosis (Degos disease). (16421135)
2006
17
Image analysis of optic nerve disease. (15534606)
2004
18
Gene therapy for optic nerve disease. (15534589)
2004
19
Electrophysiological assessment of optic nerve disease. (15534599)
2004
20
Ultrastructural changes in the optic nerves of rodents with experimental Creutzfeldt-Jakob Disease (CJD), Gerstmann-StrAoussler-Scheinker disease (GSS) or scrapie. (12921728)
2003
21
Retinal masqueraders of optic nerve disease. (11370571)
2001
22
Optic nerve disease: an introduction. (9292246)
1997
23
Krabbe disease: an ultrastructural study of globoid cells and reactive astrocytes at the brain and optic nerves. (9595850)
1997
24
Successful surgical removal of an asymptomatic optic nerve hemangioblastoma in von Hippel-Lindau disease. (9038433)
1997
25
Establishing a reliable visual function test and applying it to screening optic nerve disease in onchocercal communities. (8735773)
1996
26
Red-dot card test of the paracentral field as a screening test for optic nerve disease in onchocerciasis. (9060216)
1996
27
Reduction in incidence of optic nerve disease with annual ivermectin to control onchocerciasis. (8093742)
1993
28
Cyclosporine effects on optic nerve and retinal vasculitis in BehAset's disease. (1425128)
1992
29
Correlation of chromatic, spatial, and temporal sensitivity in optic nerve disease. (1748555)
1991
30
The pattern electroretinogram in retinal and optic nerve disease. A quantitative comparison of the pattern of visual dysfunction. (1760971)
1991
31
The spectrum of optic nerve disease in human immunodeficiency virus infection. (2539020)
1989
32
Optic nerve coloboma associated with renal disease. (3377002)
1988
33
The differential effect of optic nerve disease on pattern and focal electroretinograms. (3665701)
1987
34
Standardized A-scan echography in optic nerve disease. (3307721)
1987
35
Optic nerve disease. (3932417)
1985
36
Brightness-sense and optic nerve disease. (3977673)
1985
37
Improvement of uveitis and optic nerve disease by cyclosporine in a patient with multiple sclerosis. (6731549)
1984
38
Edge-light pupil cycle time and optic nerve disease. (6660715)
1983
39
The pattern electroretinogram in optic nerve disease. (6646652)
1983
40
Intraorbital optic nerve hemangioblastoma with von Hippel-Lindau disease. Case report. (7199079)
1982
41
The differential diagnosis of retinal disease from optic nerve disease. (7328258)
1981
42
Suprathreshold static perimetry in glaucoma and other optic nerve disease. (233860)
1979
43
Visual function tests in retinal and optic nerve disease. (487259)
1979
44
Optic nerve glioma and phaeochromocytoma associated with von Recklinghausen's disease: A case report. (403930)
1977
45
Visually evoked responses in optic nerve disease. (1071915)
1976
46
Pupillary signs in the diagnosis of optic nerve disease. (1071916)
1976
47
Diagnostic difficulties in optic nerve disease and in papilloedema and disc oedema. (1071918)
1976
48
Problem diagnoses in optic nerve disease. (1145491)
1975
49
PSEUDO-ARGYLL ROBERTSON PUPILS IN OPTIC NERVE DISEASE. (14189742)
1964
50
Management of optic nerve disease. (14018904)
1963

Genetic Variations for Optic Nerve Disease

About this section

Expression for genes affiliated with Optic Nerve Disease

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Optic Nerve Disease

Search GEO for disease gene expression data for Optic Nerve Disease.

Pathways for genes affiliated with Optic Nerve Disease

About this section

Compounds for genes affiliated with Optic Nerve Disease

About this section

GO Terms for genes affiliated with Optic Nerve Disease

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Optic Nerve Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi membraneGO:0001399.1GRM6, OPTN

Products for genes affiliated with Optic Nerve Disease

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Optic Nerve Disease

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet