MCID: OPT007
MIFTS: 41

Optic Nerve Glioma

Categories: Cancer diseases, Neuronal diseases, Eye diseases

Aliases & Classifications for Optic Nerve Glioma

MalaCards integrated aliases for Optic Nerve Glioma:

Name: Optic Nerve Glioma 12 42 14 69
Glioma of the Optic Nerve 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4992
MeSH 42 D020339
NCIt 47 C4537
SNOMED-CT 64 254976006 404662003
UMLS 69 C0346326

Summaries for Optic Nerve Glioma

MalaCards based summary : Optic Nerve Glioma, also known as glioma of the optic nerve, is related to cerebellar astrocytoma and childhood optic nerve glioma. An important gene associated with Optic Nerve Glioma is NES (Nestin), and among its related pathways/superpathways are Neuroscience and Spinal Cord Injury. The drugs Dacarbazine and Temozolomide have been mentioned in the context of this disorder. Affiliated tissues include brain, t cells and spinal cord, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 72 Optic nerve glioma (or optic glioma), a form of glioma which affects the optic nerve, is often one of... more...

Related Diseases for Optic Nerve Glioma

Diseases related to Optic Nerve Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 240)
id Related Disease Score Top Affiliating Genes
1 cerebellar astrocytoma 30.3 GFAP SYP
2 childhood optic nerve glioma 12.2
3 sella turcica neoplasm 10.9 GFAP NES
4 anaplastic plasmacytoma 10.9 GFAP NES
5 nodular medulloblastoma 10.9 ENO2 GFAP
6 logopenic progressive aphasia 10.8 MUC1 S100B
7 heiner syndrome 10.8 MUC1 S100B
8 integrative agnosia 10.8 ENO2 MBP
9 esophagus leiomyosarcoma 10.8 GFAP VIM
10 macular retinal edema 10.8 GFAP NES
11 dedifferentiated liposarcoma 10.8 MUC1 S100B
12 immune-mediated encephalomyelitis 10.8 S100B VIM
13 endotheliitis 10.8 ENO2 MBP
14 myeloid/lymphoid neoplasm associated with pdgfra rearrangement 10.8 MUC1 VIM
15 simple cryoglobulinemia 10.8 MUC1 S100B
16 ovarian mucinous cystadenofibroma 10.7 GFAP S100B
17 morbid obesity 10.7 ENO2 MUC1
18 vulvar benign neoplasm 10.7 ENO2 GFAP
19 pineal region yolk sac tumor 10.7 ENO2 VIM
20 basosquamous carcinoma 10.7 GFAP VIM
21 intellectual disability-polydactyly-uncombable hair syndrome 10.7 ENO2 GFAP VIM
22 cortical blindness 10.7 TNFRSF11B VIM
23 mannose-binding lectin protein deficiency 10.7 MUC1 VIM
24 spleen cancer 10.7 NF1 S100B
25 motor neuron disease 10.7 ENO2 S100B
26 laryngeal neuroendocrine tumor 10.7 GFAP MUC1 VIM
27 cervical keratinizing squamous cell carcinoma 10.7 ENO2 NF1
28 pyoderma 10.7 GFAP MUC1 VIM
29 myxoid leiomyosarcoma 10.7 ENO2 VIM
30 vulvar angiokeratoma 10.7 MUC1 VIM
31 mucinous ovarian cystadenoma 10.7 GFAP MUC1 S100B
32 glioma 10.7
33 subependymal glioma 10.7 GFAP MUC1 VIM
34 benallegue lacete syndrome 10.6 ENO2 S100B VIM
35 phobic disorder 10.6 ENO2 MUC1 S100B
36 mediastinal osteogenic sarcoma 10.6 ENO2 MUC1 VIM
37 demyelinating disease 10.6 ENO2 GFAP NF1
38 cystitis 10.6 GFAP MUC1 VIM
39 noninvasive malignant thymoma 10.6 MUC1 S100B VIM
40 connective tissue cancer 10.6 ENO2 GFAP S100B
41 pancreatic intraductal papillary-colloid carcinoma 10.6 MUC1 S100B VIM
42 osteopetrosis and infantile neuroaxonal dystrophy 10.6 NES S100B VIM
43 lice infestation 10.6 MUC1 S100B VIM
44 spindle cell liposarcoma 10.6 MUC1 S100B VIM
45 coronary restenosis 10.6 MUC1 S100B VIM
46 progressive relapsing multiple sclerosis 10.6 ENO2 MBP S100B
47 paranasal sinus cancer 10.6 ENO2 SYP
48 ampulla of vater small cell carcinoma 10.6 ENO2 SYP
49 devriendt syndrome 10.6 GFAP SYP
50 dense deposit disease 10.6 MUC1 S100B VIM

Graphical network of the top 20 diseases related to Optic Nerve Glioma:



Diseases related to Optic Nerve Glioma

Symptoms & Phenotypes for Optic Nerve Glioma

MGI Mouse Phenotypes related to Optic Nerve Glioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.15 ENO2 FABP7 GFAP LOX MAP2 MBP
2 cardiovascular system MP:0005385 9.97 NF1 TNFRSF11B TP53 VIM GFAP H2AFX
3 cellular MP:0005384 9.96 GFAP H2AFX MBP MIB1 MTO1 NF1
4 homeostasis/metabolism MP:0005376 9.93 GFAP H2AFX LOX MBP MIB1 MTO1
5 mortality/aging MP:0010768 9.73 GFAP H2AFX LOX MAP2 MBP MIB1
6 nervous system MP:0003631 9.32 ENO2 FABP7 GFAP MAP2 MBP MIB1

Drugs & Therapeutics for Optic Nerve Glioma

Drugs for Optic Nerve Glioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 99)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dacarbazine Approved, Investigational Phase 3,Phase 1,Phase 2,Early Phase 1 4342-03-4 5351166
2
Temozolomide Approved, Investigational Phase 3,Phase 1,Phase 2,Early Phase 1 85622-93-1 5394
3
Carboplatin Approved Phase 3,Phase 1,Phase 2 41575-94-4 10339178 498142 38904
4 Alkylating Agents Phase 3,Phase 1,Phase 2,Early Phase 1
5
Irinotecan Approved, Investigational Phase 2,Phase 1 97682-44-5, 100286-90-6 60838
6
Oxaliplatin Approved, Investigational Phase 2,Phase 1 61825-94-3 5310940 9887054 43805 6857599
7
Lenalidomide Approved Phase 2,Phase 1 191732-72-6 216326
8
Bevacizumab Approved, Investigational Phase 1, Phase 2 216974-75-3
9
Mebendazole Approved, Vet_approved Phase 1, Phase 2 31431-39-7 4030
10
Piperazine Approved, Vet_approved Phase 1, Phase 2 110-85-0 4837
11
Vincristine Approved, Investigational Phase 1, Phase 2 2068-78-2, 57-22-7 5978
12
Peginterferon alfa-2b Approved Phase 2 99210-65-8, 215647-85-1
13
Trioxsalen Approved Phase 2,Phase 1 3902-71-4 5585
14
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
15
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
16
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938
17
Nicotinamide Approved, Nutraceutical Phase 2 98-92-0 936
18
tipifarnib Investigational Phase 2 192185-72-1 159324
19
Camptothecin Experimental Phase 2,Phase 1 7689-03-4
20 Antineoplastic Agents, Phytogenic Phase 2,Phase 1
21 topoisomerase I inhibitors Phase 2,Phase 1
22 Topoisomerase Inhibitors Phase 2,Phase 1
23 Angiogenesis Inhibitors Phase 1, Phase 2
24 Angiogenesis Modulating Agents Phase 1, Phase 2
25 Anti-Infective Agents Phase 1, Phase 2
26 Anti-Bacterial Agents Phase 2,Phase 1
27 Immunosuppressive Agents Phase 2,Phase 1
28 Protein Kinase Inhibitors Phase 2,Phase 1
29 Anthelmintics Phase 1, Phase 2
30 Anticonvulsants Phase 1, Phase 2
31 Antimitotic Agents Phase 1, Phase 2
32 Antiparasitic Agents Phase 1, Phase 2
33 Piperazine citrate Phase 1, Phase 2
34 Antiviral Agents Phase 2
35 Interferon-alpha Phase 2
36 interferons Phase 2
37 Dermatologic Agents Phase 2,Phase 1
38 Dihematoporphyrin Ether Phase 2,Phase 1
39 Ether Phase 2,Phase 1
40 Hematoporphyrin Derivative Phase 2,Phase 1
41 Hematoporphyrins Phase 2,Phase 1
42 Pharmaceutical Solutions Phase 2
43 Photosensitizing Agents Phase 2,Phase 1
44 Micronutrients Phase 2
45 Nicotinic Acids Phase 2
46 Trace Elements Phase 2
47 Vitamin B Complex Phase 2
48 Vitamins Phase 2
49 Citrate Nutraceutical Phase 1, Phase 2
50
Citric Acid Nutraceutical, Vet_approved Phase 1, Phase 2 77-92-9 311

Interventional clinical trials:

(show all 38)

id Name Status NCT ID Phase Drugs
1 Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma Withdrawn NCT01260103 Phase 3 Temozolomide;ANP Therapy
2 Antineoplaston Therapy in Treating Children With Visual Pathway Glioma Completed NCT00003477 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
3 Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy Completed NCT00679354 Phase 2 cilengitide
4 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2 tipifarnib
5 Irinotecan in Treating Children With Refractory Solid Tumors Completed NCT00004078 Phase 2 irinotecan hydrochloride
6 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment Completed NCT00091182 Phase 2 oxaliplatin
7 A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Recruiting NCT01837862 Phase 1, Phase 2 Mebendazole;Vincristine;Carboplatin;Temozolomide;Bevacizumab;Irinotecan
8 Phase II Pegylated Interferon Recruiting NCT02343224 Phase 2 Pegylated interferon alpha-2b
9 Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma Recruiting NCT02839720 Phase 2 Selumetinib
10 Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas Recruiting NCT01966809 Phase 2 Photofrin photodynamic therapy.
11 Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma Recruiting NCT01089101 Phase 1, Phase 2 Selumetinib
12 Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma Active, not recruiting NCT01553149 Phase 2 Lenalidomide
13 Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas Terminated NCT01338857 Phase 2 Sorafenib (Nexavar)
14 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
15 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
16 ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors Completed NCT00946335 Phase 1 veliparib;temozolomide
17 Cilengitide in Treating Children With Refractory Primary Brain Tumors Completed NCT00063973 Phase 1 cilengitide
18 Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors Completed NCT00052780 Phase 1 O6-benzylguanine;temozolomide
19 Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas Completed NCT00012181 Phase 1 alvocidib
20 Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors Completed NCT00100880 Phase 1 lenalidomide
21 AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors Completed NCT00326664 Phase 1 Cediranib Maleate
22 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
23 Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas Completed NCT00101270 Phase 1 irinotecan hydrochloride;oxaliplatin
24 Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma Completed NCT00363272 Phase 1 ispinesib
25 FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia Completed NCT00053963 Phase 1 romidepsin
26 Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors Recruiting NCT02372409 Phase 1 Doxorubicin;Etoposide
27 Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors Recruiting NCT01682746 Phase 1 Photofrin (porfimer sodium) & photodynamic therapy.
28 Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors Recruiting NCT02780804 Phase 1 Entinostat
29 Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors Active, not recruiting NCT02415153 Phase 1 Pomalidomide
30 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
31 Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1. Unknown status NCT02078401
32 Natural History Study of Patients With Neurofibromatosis Type I Recruiting NCT00924196
33 Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Recruiting NCT00919750
34 PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1) Active, not recruiting NCT01800032
35 Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor Active, not recruiting NCT00638898 busulfan;melphalan;topotecan hydrochloride
36 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas Terminated NCT02175745 18F-fluoro-dihydroxyphenylalanine
37 Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas Withdrawn NCT02976441 Early Phase 1 Temozolomide
38 Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors Withdrawn NCT02194452

Search NIH Clinical Center for Optic Nerve Glioma

Cochrane evidence based reviews: optic nerve glioma

Genetic Tests for Optic Nerve Glioma

Anatomical Context for Optic Nerve Glioma

MalaCards organs/tissues related to Optic Nerve Glioma:

39
Brain, T Cells, Spinal Cord, Eye, Colon

Publications for Optic Nerve Glioma

Articles related to Optic Nerve Glioma:

(show top 50) (show all 84)
id Title Authors Year
1
Prechiasmatic transection of the optic nerve in optic nerve glioma: technical description and surgical outcome. ( 27230830 )
2016
2
Optic nerve glioma with complete intraocular extension. ( 27830210 )
2016
3
Childhood Optic Nerve Glioma: Vision Loss Due to Biopsy. ( 27046034 )
2016
4
Teaching NeuroImages: Optic nerve glioma with perineural arachnoid gliomatosis in a patient with neurofibromatosis-1. ( 25825471 )
2015
5
Anisometropia in children with neurofibromatosis type 1 and unilateral optic nerve glioma. ( 24924279 )
2014
6
Optic nerve glioma: case series with review of clinical, radiologic, molecular, and histopathologic characteristics. ( 24762952 )
2014
7
Optic nerve glioma: A great mimicker. ( 24575324 )
2014
8
Optic nerve glioma: an update. ( 24736941 )
2014
9
An 80-year experience with optic nerve glioma cases at the Armed Forces Institute of Pathology: evolution from museum to molecular evaluation suggests possibe interventions in the cellular senescence and microglial pathways (an American Ophthalmological Society thesis). ( 25411512 )
2014
10
Aggressive Low-Grade Optic Nerve Glioma in Adults. ( 27928317 )
2014
11
Optic nerve glioma treatment with fractionated stereotactic radiotherapy. ( 23495806 )
2013
12
Accuracy of MRI in defining tumor-free margin in optic nerve glioma surgery. ( 23715516 )
2013
13
Surgical management of an optic nerve glioma with perineural arachnoidal gliomatosis growth pattern. ( 23149617 )
2013
14
Fractionated stereotactic radiotherapy using Novalis for confined intra-orbital optic nerve glioma in pediatric patient. ( 23338672 )
2013
15
Myopia associated with optic nerve gliomas in neurofibromatosis type 1. ( 22370674 )
2012
16
Morning glory disc anomaly in association with ipsilateral optic nerve glioma. ( 22893090 )
2012
17
Diagnosis and management of optic nerve glioma. ( 22071462 )
2011
18
Neovascular glaucoma following stereotactic radiosurgery for an optic nerve glioma: a case report. ( 20714392 )
2010
19
Diagnostic pitfall: optic neuritis mimicking optic nerve glioma. ( 18721230 )
2009
20
Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report. ( 19820802 )
2009
21
Optic nerve sheath fenestration for an isolated optic nerve glioma. ( 18930671 )
2009
22
Magnetic resonance imaging evidence of optic nerve glioma progression into and beyond the optic chiasm. ( 19033845 )
2008
23
Electrophysiological monitoring in a patient with an optic nerve glioma. ( 18301934 )
2008
24
Assessment of chemotherapeutic response in children with proptosis due to optic nerve glioma. ( 18157537 )
2008
25
Adult optic nerve glioma presenting as central retinal vein occlusion. ( 25390231 )
2007
26
Retrobulbar cysticercosis masquerading as optic nerve glioma. ( 17510876 )
2007
27
Significant improvement of visual functions after removal of an intracranial giant optic nerve glioma revealing exophytic growth: case report. ( 16575300 )
2006
28
Malignant optic nerve glioma (glioblastoma multiforme): A case report and literature review. ( 17111679 )
2006
29
Natural history of neurofibromatosis 1-associated optic nerve glioma in mice. ( 15622533 )
2005
30
Optic nerve glioma and optic neuritis mimicking one another: case report. ( 15987555 )
2005
31
Optic nerve glioma in neurofibromatosis-I. ( 15695867 )
2005
32
Optic nerve glioma and colonic polyposis: report of a new association. ( 15384896 )
2004
33
Unilateral adult malignant optic nerve glioma. ( 15085353 )
2004
34
Optic nerve glioma manifesting as intratumoral hemorrhage in a pregnant woman--case report. ( 14705324 )
2003
35
Malignant optic nerve glioma: metastases to the spinal neuraxis. Case illustration. ( 12546402 )
2003
36
Recent advances in optic nerve glioma with a focus on the young patient. ( 14624073 )
2003
37
Optic nerve glioma in a patient with von Hippel-Lindau syndrome. ( 12580276 )
2003
38
Optic nerve glioma. ( 12956473 )
2003
39
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. ( 14695164 )
2003
40
Oncodiagnosis panel: 2002. Optic nerve glioma or optic nerve meningioma. ( 14635617 )
2003
41
Optic nerve glioma in infancy: a case report of the youngest patient in Thailand. ( 11529326 )
2001
42
Optic nerve glioma. ( 11374634 )
2001
43
Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy. ( 11146372 )
2000
44
Bilateral optic nerve glioma. ( 10708361 )
1999
45
Choroidal neovascular membrane as a feature of optic nerve glioma. ( 9279953 )
1997
46
Large optic nerve glioma. ( 9715321 )
1996
47
Primary benign tumors of the orbital cavity: comparative data in a series of patients with optic nerve glioma, sheath meningioma, or neurinoma. ( 8607065 )
1996
48
Cerebro-vasculopathy and malignancy: catastrophic complications of radiotherapy for optic nerve glioma in a von Recklinghausen neurofibromatosis patient. ( 8738366 )
1996
49
Optic nerve glioma mimicking an optic nerve meningioma. ( 8884101 )
1996
50
Optic nerve glioma presenting as a huge intrasellar mass. Case report. ( 7891196 )
1994

Variations for Optic Nerve Glioma

Cosmic variations for Optic Nerve Glioma:

9
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM476 BRAF central nervous system,optic nerve,glioma,NS c.1799T>A p.V600E 9

Expression for Optic Nerve Glioma

Search GEO for disease gene expression data for Optic Nerve Glioma.

Pathways for Optic Nerve Glioma

Pathways related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 12.07 ENO2 FABP7 GFAP MAP2 MBP NF1
2 11.54 GFAP MBP TP53 VIM
3
Show member pathways
11.47 GFAP NES VIM
4 11.07 FABP7 GFAP MAP2 NES S100B SYP

GO Terms for Optic Nerve Glioma

Cellular components related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell body GO:0044297 8.32 FABP7

Biological processes related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.26 MUC1 TP53
2 extracellular matrix organization GO:0030198 9.13 LOX NF1 TNFRSF11B
3 intermediate filament organization GO:0045109 9.07 VIM
4 astrocyte development GO:0014002 9.02 VIM
5 Bergmann glial cell differentiation GO:0060020 8.85 VIM
6 intermediate filament-based process GO:0045103 8.32 VIM

Molecular functions related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.43 GFAP OPTN S100B SYP TP53 VIM
2 structural molecule activity GO:0005198 8.8 MAP2 NES VIM

Sources for Optic Nerve Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
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70 UMLS via Orphanet
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