MCID: OPT007
MIFTS: 41

Optic Nerve Glioma malady

Categories: Cancer diseases, Neuronal diseases, Eye diseases

Aliases & Classifications for Optic Nerve Glioma

Aliases & Descriptions for Optic Nerve Glioma:

Name: Optic Nerve Glioma 12 42 14 69
Glioma of the Optic Nerve 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4992
MeSH 42 D020339
NCIt 47 C4537
SNOMED-CT 64 254976006 404662003
UMLS 69 C0346326

Summaries for Optic Nerve Glioma

MalaCards based summary : Optic Nerve Glioma, also known as glioma of the optic nerve, is related to childhood optic nerve glioma and glioma. An important gene associated with Optic Nerve Glioma is NES (Nestin), and among its related pathways/superpathways are Neuroscience and Spinal Cord Injury. The drugs Carmustine and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include eye, colon and brain, and related phenotypes are behavior/neurological and cellular

Wikipedia : 71 Optic nerve glioma (or optic glioma), a form of glioma which affects the optic nerve, is often one of... more...

Related Diseases for Optic Nerve Glioma

Diseases related to Optic Nerve Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 196)
id Related Disease Score Top Affiliating Genes
1 childhood optic nerve glioma 12.2
2 glioma 10.7
3 lucey-driscoll syndrome 10.3 MUC1 S100B
4 secondary pulmonary hemosiderosis 10.3 MUC1 S100B
5 hypothalamic neoplasm 10.3 GFAP NES
6 angiofollicular lymph hyperplasia 10.3 GFAP NES
7 lupus - neurological sequelae 10.3 S100B VIM
8 benign schwannoma 10.3 ENO2 S100B VIM
9 invasive mole 10.3 MUC1 S100B
10 myoma 10.3 MUC1 S100B VIM
11 uterine corpus leiomyomatosis 10.3 ENO2 MUC1 S100B
12 postgerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma 10.3 MUC1 S100B VIM
13 subglottis verrucous carcinoma 10.3 MUC1 S100B VIM
14 clear cell ependymoma 10.3 MUC1 S100B VIM
15 mediastinum liposarcoma 10.3 MUC1 S100B VIM
16 endometrial stromal sarcoma 10.3 GFAP MUC1 VIM
17 ovarian cystadenoma 10.3 GFAP MUC1 S100B
18 cauda equina intradural extramedullary astrocytoma 10.3 GFAP MUC1 VIM
19 ovarian papillary neoplasm 10.3 ENO2 MUC1 VIM
20 gastrointestinal system cancer 10.2 MUC1 S100B VIM
21 jejunal somatostatinoma 10.2 ENO2 GFAP NF1
22 diarrhea, chronic, with villous atrophy 10.2 MUC1 S100B VIM
23 desmoid tumor 10.2 MUC1 S100B VIM
24 ovarian epithelial cancer 10.2 NES S100B VIM
25 popliteal pterygium syndrome, bartsocas-papas type 10.2 MUC1 S100B VIM
26 ovarian insufficiency due to fsh resistance 10.2 MUC1 NF1 VIM
27 mirror agnosia 10.2 ENO2 MBP
28 urea cycle disorder 10.2 GFAP MBP S100B
29 infiltrating renal pelvis transitional cell carcinoma 10.2 ENO2 SYP
30 mongolian spot 10.2 MUC1 NF1 S100B
31 thymus small cell carcinoma 10.2 ENO2 SYP
32 diphtheria 10.2 ENO2 MIB1 NF1
33 skeletal-extraskeletal angiomatosis 10.2 ENO2 MUC1 SYP
34 prolactin producing pituitary tumor 10.2 ENO2 MUC1 SYP
35 liver fibrosarcoma 10.2 GFAP TP53
36 epidural abscess 10.2 ENO2 MIB1 NF1
37 diabetes hypogonadism deafness mental retardation 10.2 GFAP SYP
38 connective tissue cancer 10.2 ENO2 GFAP S100B
39 papillary tumor of the pineal region 10.2 GFAP SYP
40 preretinal fibrosis 10.2 MUC1 TNFRSF11B VIM
41 bronchiolitis obliterans 10.2 GFAP MAP2 NES
42 thymoma 10.2 ENO2 MUC1 SYP
43 persistent vegetative state 10.2 MAP2 NES VIM
44 myelinoclastic diffuse sclerosis 10.2 ENO2 GFAP MUC1 S100B
45 corneal intraepithelial neoplasm 10.2 MUC1 S100B SYP
46 sebaceous adenoma 10.2 MUC1 SYP VIM
47 vaginal villous adenoma 10.2 MBP MUC1 SYP
48 dysgerminoma of ovary 10.2 GFAP NES SYP
49 brain stem ependymoma 10.2 GFAP SYP
50 gestational trophoblastic neoplasm 10.2 MUC1 SYP VIM

Graphical network of the top 20 diseases related to Optic Nerve Glioma:



Diseases related to Optic Nerve Glioma

Symptoms & Phenotypes for Optic Nerve Glioma

MGI Mouse Phenotypes related to Optic Nerve Glioma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.22 TP53 VIM ENO2 FABP7 GFAP LOX
2 cellular MP:0005384 10.06 NF1 SOX3 TNFRSF11B TP53 VIM ENO2
3 cardiovascular system MP:0005385 10.02 GFAP H2AFX LOX MIB1 MTO1 NF1
4 growth/size/body region MP:0005378 10 MIB1 MTO1 NF1 SOX3 TNFRSF11B TP53
5 homeostasis/metabolism MP:0005376 9.97 FABP7 GFAP H2AFX LOX MBP MIB1
6 mortality/aging MP:0010768 9.77 GFAP H2AFX LOX MAP2 MBP MIB1
7 nervous system MP:0003631 9.36 FABP7 GFAP MAP2 MBP MIB1 NF1

Drugs & Therapeutics for Optic Nerve Glioma

Drugs for Optic Nerve Glioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 147)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carmustine Approved Phase 3 154-93-8 2578
2
Lenograstim Approved Phase 3,Phase 1 135968-09-1
3
Carboplatin Approved Phase 3,Phase 1,Phase 2 41575-94-4 10339178 498142 38904
4
Dacarbazine Approved, Investigational Phase 3,Phase 1,Phase 2,Early Phase 1 4342-03-4 5351166
5
Temozolomide Approved, Investigational Phase 3,Phase 1,Phase 2,Early Phase 1 85622-93-1 5394
6 Alkylating Agents Phase 3,Phase 1,Phase 2,Early Phase 1
7 Antineoplastic Agents, Alkylating Phase 3,Phase 1,Phase 2,Early Phase 1
8 O(6)-benzylguanine Phase 3,Phase 1
9 Adjuvants, Immunologic Phase 3,Phase 1
10
Irinotecan Approved, Investigational Phase 2,Phase 1,Early Phase 1 97682-44-5, 100286-90-6 60838
11
Bevacizumab Approved, Investigational Phase 1, Phase 2, Early Phase 1 216974-75-3
12
Oxaliplatin Approved, Investigational Phase 2,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
13
Lenalidomide Approved Phase 2,Phase 1 191732-72-6 216326
14
Mebendazole Approved, Vet_approved Phase 1, Phase 2 31431-39-7 4030
15
Piperazine Approved, Vet_approved Phase 1, Phase 2 110-85-0 4837
16
Vincristine Approved, Investigational Phase 1, Phase 2 2068-78-2, 57-22-7 5978
17
Peginterferon alfa-2b Approved Phase 2 99210-65-8, 215647-85-1
18
Trioxsalen Approved Phase 2,Phase 1 3902-71-4 5585
19
Cetuximab Approved Phase 1, Phase 2 205923-56-4 56842117 2333
20
Vinblastine Approved Phase 2 865-21-4 13342 241903
21
Lomustine Approved Phase 2 13010-47-4 3950
22
Acetaminophen Approved Phase 2 103-90-2 1983
23
Dexamethasone Approved, Investigational, Vet_approved Phase 2,Phase 1 50-02-2 5743
24
Diphenhydramine Approved Phase 2 58-73-1, 147-24-0 3100
25
Promethazine Approved Phase 2 60-87-7 4927
26
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
27
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
28
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938
29
Nicotinamide Approved, Nutraceutical Phase 2 98-92-0 936
30
tipifarnib Investigational Phase 2 192185-72-1 159324
31
Camptothecin Experimental Phase 2,Phase 1 7689-03-4
32 Angiogenesis Inhibitors Phase 1, Phase 2, Early Phase 1
33 Angiogenesis Modulating Agents Phase 1, Phase 2, Early Phase 1
34 Antineoplastic Agents, Phytogenic Phase 2,Phase 1
35 topoisomerase I inhibitors Phase 2,Phase 1
36 Topoisomerase Inhibitors Phase 2,Phase 1
37 Anti-Infective Agents Phase 1, Phase 2, Early Phase 1
38 Antibodies Phase 1, Phase 2
39 Antibodies, Monoclonal Phase 1, Phase 2
40 Immunoglobulins Phase 1, Phase 2
41 Anti-Bacterial Agents Phase 2,Phase 1,Early Phase 1
42 Immunosuppressive Agents Phase 2,Phase 1,Early Phase 1
43 cadexomer iodine Phase 2,Phase 1
44
Iodine Phase 2,Phase 1 7553-56-2 807
45 Protein Kinase Inhibitors Phase 2,Phase 1
46 Anthelmintics Phase 1, Phase 2
47 Anticonvulsants Phase 1, Phase 2
48 Antimitotic Agents Phase 1, Phase 2
49 Antiparasitic Agents Phase 1, Phase 2
50 Piperazine citrate Phase 1, Phase 2

Interventional clinical trials:

(show top 50) (show all 65)
id Name Status NCT ID Phase
1 S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma Completed NCT00017147 Phase 3
2 Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer Active, not recruiting NCT01987596 Phase 3
3 Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma Withdrawn NCT01260103 Phase 3
4 Antineoplaston Therapy in Treating Children With Visual Pathway Glioma Completed NCT00003477 Phase 2
5 Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy Completed NCT00679354 Phase 2
6 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2
7 Irinotecan in Treating Children With Refractory Solid Tumors Completed NCT00004078 Phase 2
8 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment Completed NCT00091182 Phase 2
9 Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00006102 Phase 2
10 A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Recruiting NCT01837862 Phase 1, Phase 2
11 Phase II Pegylated Interferon Recruiting NCT02343224 Phase 2
12 Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas Recruiting NCT01966809 Phase 2
13 Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma Recruiting NCT01089101 Phase 1, Phase 2
14 Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery Recruiting NCT02855086 Phase 1, Phase 2
15 Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG) Recruiting NCT02840409 Phase 2
16 Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas Recruiting NCT02343406 Phase 2
17 Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma Active, not recruiting NCT01553149 Phase 2
18 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
19 Study of Laser Interstitial Thermal Therapy (LITT) in Recurrent Glioblastoma Not yet recruiting NCT03022578 Phase 2
20 Atezolizumab (aPDL1) + Temozolomide and Radiation for Newly Diagnosed Glioblastoma (GBM) Not yet recruiting NCT03174197 Phase 1, Phase 2
21 Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas Terminated NCT01338857 Phase 2
22 Panitumumab and Irinotecan for Malignant Gliomas Terminated NCT01017653 Phase 2
23 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1
24 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1
25 ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors Completed NCT00946335 Phase 1
26 Cilengitide in Treating Children With Refractory Primary Brain Tumors Completed NCT00063973 Phase 1
27 Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors Completed NCT00052780 Phase 1
28 Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas Completed NCT00012181 Phase 1
29 Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors Completed NCT00100880 Phase 1
30 AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors Completed NCT00326664 Phase 1
31 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1
32 Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas Completed NCT00101270 Phase 1
33 Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma Completed NCT00363272 Phase 1
34 FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia Completed NCT00053963 Phase 1
35 AZD7451 for Recurrent Gliomas Completed NCT01468324 Phase 1
36 Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) Completed NCT00352599 Phase 1
37 Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides Completed NCT01598454 Phase 1
38 Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer Completed NCT00003022 Phase 1
39 Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer Completed NCT00053118 Phase 1
40 Busulfan in Treating Children and Adolescents With Refractory CNS Cancer Completed NCT00006246 Phase 1
41 Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors Recruiting NCT02372409 Phase 1
42 Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors Recruiting NCT01682746 Phase 1
43 Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors Recruiting NCT02780804 Phase 1
44 Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma Recruiting NCT02709226 Phase 1
45 Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors Active, not recruiting NCT02415153 Phase 1
46 Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors Active, not recruiting NCT01331135 Phase 1
47 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1
48 MT2004-30: Tomotherapy for Solid Tumors Terminated NCT00623077 Phase 1
49 Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors Terminated NCT00003926 Phase 1
50 Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1. Unknown status NCT02078401

Search NIH Clinical Center for Optic Nerve Glioma

Cochrane evidence based reviews: optic nerve glioma

Genetic Tests for Optic Nerve Glioma

Anatomical Context for Optic Nerve Glioma

MalaCards organs/tissues related to Optic Nerve Glioma:

39
Eye, Colon, Brain

Publications for Optic Nerve Glioma

Articles related to Optic Nerve Glioma:

(show top 50) (show all 84)
id Title Authors Year
1
Prechiasmatic transection of the optic nerve in optic nerve glioma: technical description and surgical outcome. ( 27230830 )
2016
2
Childhood Optic Nerve Glioma: Vision Loss Due to Biopsy. ( 27046034 )
2016
3
Optic nerve glioma with complete intraocular extension. ( 27830210 )
2016
4
Teaching NeuroImages: Optic nerve glioma with perineural arachnoid gliomatosis in a patient with neurofibromatosis-1. ( 25825471 )
2015
5
An 80-year experience with optic nerve glioma cases at the Armed Forces Institute of Pathology: evolution from museum to molecular evaluation suggests possibe interventions in the cellular senescence and microglial pathways (an American Ophthalmological Society thesis). ( 25411512 )
2014
6
Optic nerve glioma: A great mimicker. ( 24575324 )
2014
7
Anisometropia in children with neurofibromatosis type 1 and unilateral optic nerve glioma. ( 24924279 )
2014
8
Optic nerve glioma: an update. ( 24736941 )
2014
9
Aggressive Low-Grade Optic Nerve Glioma in Adults. ( 27928317 )
2014
10
Optic nerve glioma: case series with review of clinical, radiologic, molecular, and histopathologic characteristics. ( 24762952 )
2014
11
Optic nerve glioma treatment with fractionated stereotactic radiotherapy. ( 23495806 )
2013
12
Fractionated stereotactic radiotherapy using Novalis for confined intra-orbital optic nerve glioma in pediatric patient. ( 23338672 )
2013
13
Accuracy of MRI in defining tumor-free margin in optic nerve glioma surgery. ( 23715516 )
2013
14
Surgical management of an optic nerve glioma with perineural arachnoidal gliomatosis growth pattern. ( 23149617 )
2013
15
Morning glory disc anomaly in association with ipsilateral optic nerve glioma. ( 22893090 )
2012
16
Myopia associated with optic nerve gliomas in neurofibromatosis type 1. ( 22370674 )
2012
17
Diagnosis and management of optic nerve glioma. ( 22071462 )
2011
18
Neovascular glaucoma following stereotactic radiosurgery for an optic nerve glioma: a case report. ( 20714392 )
2010
19
Optic nerve sheath fenestration for an isolated optic nerve glioma. ( 18930671 )
2009
20
Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report. ( 19820802 )
2009
21
Diagnostic pitfall: optic neuritis mimicking optic nerve glioma. ( 18721230 )
2009
22
Magnetic resonance imaging evidence of optic nerve glioma progression into and beyond the optic chiasm. ( 19033845 )
2008
23
Electrophysiological monitoring in a patient with an optic nerve glioma. ( 18301934 )
2008
24
Assessment of chemotherapeutic response in children with proptosis due to optic nerve glioma. ( 18157537 )
2008
25
Retrobulbar cysticercosis masquerading as optic nerve glioma. ( 17510876 )
2007
26
Adult optic nerve glioma presenting as central retinal vein occlusion. ( 25390231 )
2007
27
Malignant optic nerve glioma (glioblastoma multiforme): A case report and literature review. ( 17111679 )
2006
28
Significant improvement of visual functions after removal of an intracranial giant optic nerve glioma revealing exophytic growth: case report. ( 16575300 )
2006
29
Optic nerve glioma and optic neuritis mimicking one another: case report. ( 15987555 )
2005
30
Optic nerve glioma in neurofibromatosis-I. ( 15695867 )
2005
31
Natural history of neurofibromatosis 1-associated optic nerve glioma in mice. ( 15622533 )
2005
32
Optic nerve glioma and colonic polyposis: report of a new association. ( 15384896 )
2004
33
Unilateral adult malignant optic nerve glioma. ( 15085353 )
2004
34
Recent advances in optic nerve glioma with a focus on the young patient. ( 14624073 )
2003
35
Optic nerve glioma in a patient with von Hippel-Lindau syndrome. ( 12580276 )
2003
36
Optic nerve glioma manifesting as intratumoral hemorrhage in a pregnant woman--case report. ( 14705324 )
2003
37
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. ( 14695164 )
2003
38
Malignant optic nerve glioma: metastases to the spinal neuraxis. Case illustration. ( 12546402 )
2003
39
Optic nerve glioma. ( 12956473 )
2003
40
Oncodiagnosis panel: 2002. Optic nerve glioma or optic nerve meningioma. ( 14635617 )
2003
41
Optic nerve glioma. ( 11374634 )
2001
42
Optic nerve glioma in infancy: a case report of the youngest patient in Thailand. ( 11529326 )
2001
43
Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy. ( 11146372 )
2000
44
Bilateral optic nerve glioma. ( 10708361 )
1999
45
Choroidal neovascular membrane as a feature of optic nerve glioma. ( 9279953 )
1997
46
Primary benign tumors of the orbital cavity: comparative data in a series of patients with optic nerve glioma, sheath meningioma, or neurinoma. ( 8607065 )
1996
47
Optic nerve glioma mimicking an optic nerve meningioma. ( 8884101 )
1996
48
Large optic nerve glioma. ( 9715321 )
1996
49
Cerebro-vasculopathy and malignancy: catastrophic complications of radiotherapy for optic nerve glioma in a von Recklinghausen neurofibromatosis patient. ( 8738366 )
1996
50
Optic nerve glioma presenting as a huge intrasellar mass. Case report. ( 7891196 )
1994

Variations for Optic Nerve Glioma

Cosmic variations for Optic Nerve Glioma:

9
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM476 BRAF central nervous system,optic nerve,glioma,NS c.1799T>A p.V600E 9

Expression for Optic Nerve Glioma

Search GEO for disease gene expression data for Optic Nerve Glioma.

Pathways for Optic Nerve Glioma

Pathways related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 12.07 ENO2 FABP7 GFAP MAP2 MBP NF1
2 11.54 GFAP MBP TP53 VIM
3 11.07 FABP7 GFAP MAP2 NES S100B SYP

GO Terms for Optic Nerve Glioma

Cellular components related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.02 ENO2 FABP7 MAP2 MBP S100B

Biological processes related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 MUC1 TP53
2 central nervous system development GO:0007417 8.92 MBP NES S100B SOX3

Molecular functions related to Optic Nerve Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.1 GFAP OPTN S100B SYP TP53 VIM

Sources for Optic Nerve Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
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47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
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70 UMLS via Orphanet
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