MCID: OPT007
MIFTS: 41

Optic Nerve Glioma malady

Cancer diseases, Eye diseases, Neuronal diseases categories
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Summaries for Optic Nerve Glioma

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Wikipedia:65 Optic nerve glioma (or optic glioma), a form of glioma which affects the optic nerve, is often one of... more...

MalaCards based summary: Optic Nerve Glioma, also known as glioma of the optic nerve, is related to neurofibroma and astrocytoma. An important gene associated with Optic Nerve Glioma is FABP7 (fatty acid binding protein 7, brain). The compounds ganglioside and kainate have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and colon, and related mouse phenotypes are hearing/vestibular/ear and nervous system.

Aliases & Classifications for Optic Nerve Glioma

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Optic Nerve Glioma, Aliases & Descriptions:

Name: Optic Nerve Glioma 8 10 62
 
Glioma of the Optic Nerve 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Eye diseases, Neuronal diseases


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Disease Ontology8 DOID:4992
NCIt39 C4537
MeSH34 D020339

Related Diseases for Optic Nerve Glioma

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Graphical network of the top 20 diseases related to Optic Nerve Glioma:



Diseases related to optic nerve glioma

Symptoms for Optic Nerve Glioma

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Drugs & Therapeutics for Optic Nerve Glioma

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Drug clinical trials:

Search ClinicalTrials for Optic Nerve Glioma

Search NIH Clinical Center for Optic Nerve Glioma

Genetic Tests for Optic Nerve Glioma

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Anatomical Context for Optic Nerve Glioma

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MalaCards organs/tissues related to Optic Nerve Glioma:

32
Eye, Brain, Colon

Animal Models for Optic Nerve Glioma or affiliated genes

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MGI Mouse Phenotypes related to Optic Nerve Glioma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053778.5MBP, NF1, TNFRSF11B
2MP:00036318.2MBP, NF1, FABP7, NES
3MP:00053868.1MBP, NF1, FABP7, NES
4MP:00053847.7TNFRSF11B, NES, NF1, MBP

Publications for Optic Nerve Glioma

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Articles related to Optic Nerve Glioma:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
Anisometropia in children with neurofibromatosis type 1 and unilateral optic nerve glioma. (24924279)
2014
2
Optic nerve glioma: an update. (24736941)
2014
3
Optic nerve glioma: case series with review of clinical, radiologic, molecular, and histopathologic characteristics. (24762952)
2014
4
Accuracy of MRI in defining tumor-free margin in optic nerve glioma surgery. (23715516)
2013
5
Optic nerve glioma treatment with fractionated stereotactic radiotherapy. (23495806)
2013
6
Fractionated stereotactic radiotherapy using Novalis for confined intra-orbital optic nerve glioma in pediatric patient. (23338672)
2013
7
Neovascular glaucoma following stereotactic radiosurgery for an optic nerve glioma: a case report. (20714392)
2010
8
Diagnostic pitfall: optic neuritis mimicking optic nerve glioma. (18721230)
2009
9
Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report. (19820802)
2009
10
Optic nerve sheath fenestration for an isolated optic nerve glioma. (18930671)
2009
11
Electrophysiological monitoring in a patient with an optic nerve glioma. (18301934)
2008
12
Adult optic nerve glioma presenting as central retinal vein occlusion. (25390231)
2007
13
Malignant optic nerve glioma (glioblastoma multiforme): A case report and literature review. (17111679)
2006
14
Natural history of neurofibromatosis 1-associated optic nerve glioma in mice. (15622533)
2005
15
Unilateral adult malignant optic nerve glioma. (15085353)
2004
16
Optic nerve glioma in a patient with von Hippel-Lindau syndrome. (12580276)
2003
17
Optic nerve glioma. (12956473)
2003
18
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. (14695164)
2003
19
Optic nerve glioma manifesting as intratumoral hemorrhage in a pregnant woman--case report. (14705324)
2003
20
Optic nerve glioma. (11374634)
2001
21
Optic nerve glioma in infancy: a case report of the youngest patient in Thailand. (11529326)
2001
22
Bilateral optic nerve glioma. (10708361)
1999
23
Choroidal neovascular membrane as a feature of optic nerve glioma. (9279953)
1997
24
Large optic nerve glioma. (9715321)
1996
25
Cerebro-vasculopathy and malignancy: catastrophic complications of radiotherapy for optic nerve glioma in a von Recklinghausen neurofibromatosis patient. (8738366)
1996
26
Optic nerve glioma mimicking an optic nerve meningioma. (8884101)
1996
27
Primary benign tumors of the orbital cavity: comparative data in a series of patients with optic nerve glioma, sheath meningioma, or neurinoma. (8607065)
1996
28
Optic nerve glioma presenting as a huge intrasellar mass. Case report. (7891196)
1994
29
Immunohistochemical properties of human optic nerve glioma. Evidence of type 1 astrocyte origin. (1714430)
1991
30
Delayed diagnosis of optic nerve glioma: a preventable cause of visual loss. (2803378)
1989
31
Pulsating orbital plexiform neurofibroma and optic nerve glioma. (2791937)
1989
32
Optic nerve glioma and the management of optic nerve tumours in the young. (2611193)
1989
33
Orbital optic nerve glioma in adult life. (2751454)
1989
34
Acute visual loss due to a calcified optic nerve glioma. (2624916)
1989
35
Optic-nerve glioma and pregnancy. (2716632)
1989
36
Optic nerve glioma. (3411425)
1988
37
Occlusion therapy for optic nerve glioma. (3985819)
1985
38
Papilloedema caused by spinal tumour in a case of optic nerve glioma--a clinical report. (6519733)
1984
39
Chiasmatic and hypothalamic extension of optic nerve glioma. (6615308)
1983
40
Optic nerve glioma and neovascular glaucoma: report of a case. (6174146)
1982
41
Long-term survival with optic nerve glioma. (7444747)
1980
42
Optic nerve glioma. (7418349)
1980
43
Optic nerve glioma: the role of radiation therapy. (922656)
1977
44
Large optic nerve glioma with normal vision. (1180757)
1975
45
Optic nerve glioma in an 18-month-old child. (1119518)
1975
46
The diencephalic syndrome in infants. A review in relation to optic nerve glioma. (4659145)
1972
47
Optic nerve glioma. (6054905)
1967
48
Hemorrhagic glaucoma with optic nerve glioma. (5936809)
1966
49
An electron microscopic study of normal optic nerve and of an optic-nerve glioma. (13764421)
1961
50
Bilateral optic nerve glioma with misleading encephalogram. (13494593)
1957

Variations for Optic Nerve Glioma

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Expression for genes affiliated with Optic Nerve Glioma

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Expression patterns in normal tissues for genes affiliated with Optic Nerve Glioma

Search GEO for disease gene expression data for Optic Nerve Glioma.

Pathways for genes affiliated with Optic Nerve Glioma

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Compounds for genes affiliated with Optic Nerve Glioma

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Compounds related to Optic Nerve Glioma according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1ganglioside449.6NES, MBP
2kainate44 2810.6MBP, NES
3prednisolone44 28 1111.4MBP, TNFRSF11B
4oleic acid44 28 24 1112.4NF1, FABP7
5choline44 24 1111.3NES, MBP
6indomethacin44 28 61 1112.3MBP, TNFRSF11B
7gaba449.3NES, FABP7, MBP
8glutamate449.1NES, FABP7, MBP
9methotrexate50 44 1111.0MBP, TNFRSF11B
10paraffin448.9MBP, NF1, NES
11arachidonic acid44 28 24 1111.8NF1, FABP7, TNFRSF11B
12forskolin44 50 1110.8TNFRSF11B, NF1, MBP
13progesterone44 28 61 24 1112.7NF1, NES, TNFRSF11B
14cysteine448.5MBP, NF1, TNFRSF11B
15estrogen448.3MBP, NF1, NES, TNFRSF11B
16tyrosine448.2TNFRSF11B, NES, NF1, MBP
17retinoic acid44 248.9MBP, NF1, FABP7, NES, TNFRSF11B
18lipid447.8TNFRSF11B, NES, FABP7, NF1, MBP

GO Terms for genes affiliated with Optic Nerve Glioma

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Cellular components related to Optic Nerve Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:0430259.5MBP, FABP7

Biological processes related to Optic Nerve Glioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1brain developmentGO:0074209.1NF1, NES
2central nervous system developmentGO:0074179.1MBP, NES

Products for genes affiliated with Optic Nerve Glioma

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Sources for Optic Nerve Glioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
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36MGI
39NCIt
40NDF-RT
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58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet