MCID: ORL013
MIFTS: 51

Oral Lichen Planus

Categories: Rare diseases, Oral diseases

Aliases & Classifications for Oral Lichen Planus

MalaCards integrated aliases for Oral Lichen Planus:

Name: Oral Lichen Planus 49
Oral Lichenoid Lesions 49
Lichen Planus, Oral 69
Lichen Planus Oral 51

Classifications:



External Ids:

UMLS 69 C0206139

Summaries for Oral Lichen Planus

NIH Rare Diseases : 49 Oral lichen planus is a inflammatory condition that affects the inside of the mouth.  Signs and symptoms include patches of fine white lines and dots most commonly in the inside of the cheeks, gums, and/or tongue. Most people with lichen planus experience no to few symptoms, others may have painful sores or ulcers in the mouth. Severe lichen planus slightly increases the risk for oral cancer. Oral lichen planus may occur alone or in combination with other skin forms of lichen planus. Last updated: 7/20/2011

MalaCards based summary : Oral Lichen Planus, also known as oral lichenoid lesions, is related to vulvovaginitis and dermatomyositis, and has symptoms including oral manifestations An important gene associated with Oral Lichen Planus is TP63 (Tumor Protein P63), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Tacrolimus and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include tongue, skin and t cells, and related phenotypes are Decreased influenza A H1N1 (A/Hamburg/04/2009) virus numbers and cardiovascular system

Related Diseases for Oral Lichen Planus

Diseases related to Oral Lichen Planus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 vulvovaginitis 30.3 CCL5 HSPD1
2 dermatomyositis 30.2 ICAM1 IL1A VCAM1
3 systemic lupus erythematosus 29.4 CCL5 CCR5 CXCR3 ICAM1 VCAM1
4 lichen planus 11.3
5 hepatitis 10.6
6 hepatitis c 10.6
7 squamous cell carcinoma 10.6
8 leukoplakia 10.5
9 hepatitis c virus 10.5
10 oral squamous cell carcinoma 10.5
11 lymphocytic vasculitis 10.5 ICAM1 VCAM1
12 heterophyiasis 10.4 CASP3 ICAM1
13 whiplash 10.4 CCL5 CCR5
14 gingivitis 10.4
15 mooren's ulcer 10.4 ICAM1 VCAM1
16 subendocardial myocardial infarction 10.3 ICAM1 VCAM1
17 dengue disease 10.3 CCL5 ICAM1 VCAM1
18 periodontitis 10.3
19 oral leukoplakia 10.3
20 trypanosomiasis 10.3 CCL5 ICAM1 VCAM1
21 immune-complex glomerulonephritis 10.3 CCR5 ICAM1 VCAM1
22 crescentic glomerulonephritis 10.3 CCR5 ICAM1 VCAM1
23 rhinitis 10.3 CCL5 ICAM1 VCAM1
24 idiopathic neutropenia 10.3 CASP3 CCL5 IL1A
25 mucositis 10.3
26 thyroiditis 10.2
27 burns 10.2
28 pemphigus 10.2
29 stomatitis 10.2
30 burning mouth syndrome 10.2
31 internal hemorrhoid 10.2 CASP3 MMP1
32 periodontitis, aggressive, 1 10.2 IL1A MMP1
33 oral cancer 10.2
34 chronic venous insufficiency 10.2 ICAM1 MMP1 VCAM1
35 venous insufficiency 10.2 ICAM1 MMP1 VCAM1
36 arteriosclerosis 10.2 HSPD1 ICAM1 VCAM1
37 synovitis 10.2 ICAM1 MMP1 VCAM1
38 cholesteatoma of middle ear 10.1 ICAM1 IL1A MMP1
39 chronic eosinophilic pneumonia 10.1 CCL5 CXCR3 ICAM1
40 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1
41 hypothyroidism 10.1
42 pemphigus vulgaris, familial 10.1
43 papilloma 10.1
44 pemphigus vulgaris 10.1
45 autoinflammation, lipodystrophy, and dermatosis syndrome 10.1 CCL5 ICAM1 IL1A VCAM1
46 vernal keratoconjunctivitis 10.1 CCL5 CXCR3 ICAM1
47 rheumatoid vasculitis 10.1 ICAM1 VCAM1
48 radiculopathy 10.1 CCL5 CXCR3 IL1A
49 orofacial granulomatosis 10.1 CCL5 CCR5 CXCR3
50 squamous cell carcinoma of the hypopharynx 10.1 MMP1 TIMP2

Graphical network of the top 20 diseases related to Oral Lichen Planus:



Diseases related to Oral Lichen Planus

Symptoms & Phenotypes for Oral Lichen Planus

UMLS symptoms related to Oral Lichen Planus:


oral manifestations

GenomeRNAi Phenotypes related to Oral Lichen Planus according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased influenza A H1N1 (A/Hamburg/04/2009) virus numbers GR00195-A-3 8.8 CD58 HSPD1 IL1A

MGI Mouse Phenotypes related to Oral Lichen Planus:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.97 VCAM1 CXCR3 ICAM1 IL1A CASP3 TIMP2
2 hematopoietic system MP:0005397 9.97 VCAM1 CXCR3 ICAM1 BAX IL1A CASP3
3 homeostasis/metabolism MP:0005376 9.96 VCAM1 CXCR3 ICAM1 BAX IL1A CASP3
4 immune system MP:0005387 9.9 ICAM1 BAX IL1A CASP3 MMP1 TIMP2
5 muscle MP:0005369 9.43 HSPD1 ICAM1 BAX CASP3 CCR5 TP63
6 neoplasm MP:0002006 9.17 ICAM1 BAX IL1A MMP1 CCR5 TP63

Drugs & Therapeutics for Oral Lichen Planus

Drugs for Oral Lichen Planus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tacrolimus Approved, Investigational Phase 4,Phase 2 104987-11-3 445643 439492
2
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 124-94-7 31307
3
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
4
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2 137071-32-0 17753757 6447131
5
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
6
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Early Phase 1 22916-47-8 4189
8
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
9 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1
10
Glucosamine Approved, Investigational, Nutraceutical Phase 4 3416-24-8 439213
11
Chitosan Approved, Nutraceutical Phase 4 9012-76-4 71853
12
Lycopene Approved, Investigational, Nutraceutical Phase 4,Phase 2 502-65-8 446925
13
Lactitol Investigational Phase 4 585-86-4 3871
14 triamcinolone acetonide Phase 4,Phase 3,Phase 2,Early Phase 1
15 Analgesics Phase 4,Phase 3,Phase 2
16 glucocorticoids Phase 4,Phase 3,Phase 2,Early Phase 1
17 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Early Phase 1
18 Triamcinolone diacetate Phase 4,Phase 3,Phase 2,Early Phase 1
19 Triamcinolone hexacetonide Phase 4,Phase 3,Phase 2,Early Phase 1
20 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
21 Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
22 Dermatologic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
23 Hormones Phase 4,Phase 3,Phase 2,Early Phase 1
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
25 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Early Phase 1
26 Antiemetics Phase 4,Phase 3,Phase 2,Early Phase 1
27 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Early Phase 1
28 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
29 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2
30 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Early Phase 1
32 Antioxidants Phase 4,Phase 3,Phase 2,Phase 1
33 Autonomic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
34 Antirheumatic Agents Phase 4,Phase 3,Phase 2
35 Calcineurin Inhibitors Phase 4,Phase 3,Phase 2
36 Prednisolone acetate Phase 4,Phase 2
37 Betamethasone Valerate Phase 4,Phase 3,Phase 2 2152-44-5
38 Carotenoids Phase 4,Phase 2
39 Respiratory System Agents Phase 4,Phase 3,Phase 2
40 Methylprednisolone acetate Phase 4,Phase 2
41 Methylprednisolone Hemisuccinate Phase 4,Phase 2
42 Neuroprotective Agents Phase 4
43 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
44 Antifungal Agents Phase 4,Phase 3,Early Phase 1
45 Prednisolone hemisuccinate Phase 4,Phase 2
46 Prednisolone phosphate Phase 4,Phase 2
47 Radiation-Protective Agents Phase 4,Phase 2
48 Betamethasone benzoate Phase 4,Phase 3,Phase 2
49 Betamethasone sodium phosphate Phase 4,Phase 3,Phase 2
50 Betamethasone-17,21-dipropionate Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show all 45)

# Name Status NCT ID Phase Drugs
1 Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus Completed NCT02858297 Phase 4 Glucosamine sulfate;triamcinolone acetonide
2 A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus Completed NCT02587117 Phase 4 lycopene;Prednisolone
3 Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus Completed NCT02443311 Phase 4 Pimecrolimus 1% cream;Betamethasone 17-valerate 0.1% cream
4 The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus Unknown status NCT01083420 Phase 3 Minocycline;Dexamethasone
5 Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus Completed NCT02329600 Phase 3 green tea tablets (Green tea extract 5:1) 200 mg;Triamcinolone Acetonide
6 Chamaemelum Nobile 2% Versus Placebo Topic Gel to Treat Oral Lichen Planus Completed NCT02421770 Phase 3
7 Efficacy of Elidel Cream on Erosive Oral Lichen Planus Completed NCT00130572 Phase 3 Pimecrolimus
8 Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen Terminated NCT01061853 Phase 3 TOPICAL SIROLIMUS (RAPAMUNE*);TOPICAL BETAMETHASONE 0.05%
9 A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus Unknown status NCT01524744 Phase 2 Pimecrolimus ointment;Adcortyl
10 A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus Completed NCT00525421 Phase 2 Curcuminoids;Placebo
11 Pimecrolimus Cream for Oral Lichen Planus Completed NCT00297037 Phase 2 Pimecrolimus 1% cream
12 Cedar Honey in Oral Lichen Planus Completed NCT01974414 Phase 1, Phase 2 orally administered cedar honey
13 Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus Completed NCT02744378 Phase 2 Tacrolimus 0.1%;Clobetasol 0.05%
14 Dexamethasone to Treat Oral Lichen Planus Completed NCT00111072 Phase 2 dexamethasone 0.01% solution
15 Efficacy of Purslane in Treatment of Oral Lichen Planus Completed NCT00746772 Phase 2 Purslane 235mg/day in one dosage;Placebo : one dosage
16 Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other Completed NCT00484250 Phase 2 metronidazole,doxycycline
17 Treatmant of Oral Lichen Planus With Lycopene Completed NCT00656214 Phase 2 Lycopene;Placebo
18 Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus Completed NCT02453503 Phase 2 Licorice;Triamcinolone Acetonide
19 Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planus Completed NCT00102557 Phase 2 Hydroxychloroquine
20 The Efficacy of Omega-3 in Treatment of Atrophic/Erosive Lichen Planus Completed NCT02106468 Phase 2 Prednisone tablet 5mg;Omega-3 soft capsules 1000 mg
21 Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases Completed NCT02920658 Phase 2 NAVS Naphthalan;0.05% Betamethasone dipropionate
22 Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus Recruiting NCT03026478 Phase 2 Betamethasone Dipropionate;Clobetasol Propionate
23 Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planus Recruiting NCT03386643 Phase 2 Bifidobacterium animalis subsp. lactis HN019;Clobetasol propionate 0.05%
24 Dexamethasone Solution for the Treatment of Oral Lichen Planus Recruiting NCT02850601 Phase 2 Dexamethasone
25 Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus Not yet recruiting NCT03293368 Phase 2 Triamcinolone Acetonide
26 A Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Curcuminoids in Oral Lichen Planus Terminated NCT00226174 Phase 2 Curcuminoids
27 Free Soft Tissue Graft in Treatment of Oral Lichen Planus Unknown status NCT00737854 Phase 1
28 Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus Unknown status NCT01375101 Phase 1 placebo;Quercetin
29 Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus Unknown status NCT02276573
30 Based on Metabonomics Dryness Pathogen Type of OLP: a Dynamic Study Unknown status NCT02332486 Qingxuan Decoction
31 Incidence of Esophageal Lichen Planus in Patients With Known Oral Lichen Planus Unknown status NCT02532166
32 Expression of miRNa-138 and Cyclin D1 in Oral Mucosa of Patients With Oral Lichen Planus Completed NCT02834520
33 Serum Cortisol Levels in Patients With Anxiety and Depression With Symptomatic Oral Lichen Planus Completed NCT03011658
34 Impact of Continuous Defocused CO2 Laser Vaporisation on the Histological Malignant Transformation of Erosive Oral Lichen Planus in Patients Completed NCT02154607
35 The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus Completed NCT01743690 Nystatin;fluocinolone
36 The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2) Completed NCT03257228
37 Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral Cavity Completed NCT03026361
38 Safety and Effectiveness of Efalizumab to Treat Oral Lichen Planus Completed NCT00133107 efalizumab
39 Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy Completed NCT03031899
40 Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus Recruiting NCT03415165 Early Phase 1 green tea buccal tablet;Corticosteroids Topical
41 Treatment Modalities of Oral Lichen Planus Recruiting NCT03237533 Early Phase 1 Dexamethasone
42 Use of Injectable Platelet Rich Fibrin in Lichen Planus Recruiting NCT03265093 Corticosteroid
43 The Clinical and Biological Effects Of The Use Of Probiotic VSL#3 In Patients With Oral Lichen Planus Not yet recruiting NCT03052179
44 Photobiomodulation in Oral Lichen Planus Not yet recruiting NCT03320460 Propionate clobetasol gel 0.05%
45 Tacrolimus Ointment in Oral Lichen Planus Terminated NCT01544842 0.1 % tacrolimus ointment;0.1 % triamcinolone paste;Orabase paste

Search NIH Clinical Center for Oral Lichen Planus

Genetic Tests for Oral Lichen Planus

Anatomical Context for Oral Lichen Planus

MalaCards organs/tissues related to Oral Lichen Planus:

38
Tongue, Skin, T Cells, Thyroid, Endothelial, Testes, Smooth Muscle

Publications for Oral Lichen Planus

Articles related to Oral Lichen Planus:

(show top 50) (show all 757)
# Title Authors Year
1
Participation of the Th17 response in the pathogenesis of oral lichen planus. ( 29314294 )
2018
2
Management of reticular oral lichen planus patients with burning mouth syndrome-like oral symptoms: a pilot study. ( 29308937 )
2018
3
Efficacy of photodynamic therapy in the treatment of symptomatic oral lichen planus: A systematic review. ( 29350426 )
2018
4
Psychopathological profile and quality of life of patients with oral lichen planus. ( 29364344 )
2018
5
Factors Affecting the Result of Intralesional Corticosteroid Injection in Patients With Oral Lichen Planus. ( 29366304 )
2018
6
Bacillus Calmette-Guerin, polysaccharide nucleic acid in the treatment of cutaneous and oral lichen planus. ( 29405515 )
2018
7
Evaluating the accuracy of microRNA27b and microRNA137 as biomarkers of activity and potential malignant transformation in oral lichen planus patients. ( 29368136 )
2018
8
LPS-induced Vitamin D Receptor Decrease in Oral Keratinocytes Is Associated With Oral Lichen Planus. ( 29335479 )
2018
9
Efficacy of photodynamic therapy and low level laser therapy against steroid therapy in the treatment of erosive-atrophic oral lichen planus. ( 29414735 )
2018
10
Association between hepatitis C infection in Thai patients with oral lichen planus: A case-control study. ( 29345111 )
2018
11
Randomized, placebo-controlled, double-blind trial of clobetasol propionate 0.05% in the treatment of oral lichen planus. ( 29297958 )
2018
12
Time-resolved fluorescence spectroscopy for the diagnosis of oral lichen planus. ( 29436013 )
2018
13
The association and potentially destructive role of Th9/IL-9 is synergistic with Th17 cells by elevating MMP9 production in local lesions of oral lichen planus. ( 29412487 )
2018
14
Incidence of Oral Lichen Planus in Perimenopausal Women: A Cross-sectional Study in Western Uttar Pradesh Population. ( 28706407 )
2017
15
Immune receptors CD40 and CD86 in oral keratinocytes and implications for oral lichen planus. ( 28904313 )
2017
16
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma ( 28749626 )
2017
17
Estimation of silver nucleolar organizer regions in oral lichen planus, oral lichenoid reactions and oral lichenoid dysplasia. ( 29391726 )
2017
18
Triggers of oral lichen planus flares and the potential role of trigger avoidance in disease management. ( 28732699 )
2017
19
Treatment of oral lichen planus. Systematic review and therapeutic guide. ( 28756997 )
2017
20
Increased infiltration of CD11 c<sup>+</sup>/CD123<sup>+</sup>dendritic cell subsets and upregulation of TLR/IFN-I+ signaling participate in pathogenesis of oral lichen planus. ( 29429903 )
2017
21
Successful Treatment of Oral Lichen Planus with Direct-Acting Antiviral Agents after Liver Transplantation for Hepatitis C Virus-Associated Hepatocellular Carcinoma. ( 29430221 )
2017
22
Treatment of oral lichen planus using 308-nm excimer laser. ( 28833900 )
2017
23
Semaphorin4D Drives CD8(+) T-Cell Lesional Trafficking in Oral Lichen Planus via CXCL9/CXCL10 Upregulations in OralA Keratinocytes. ( 28760660 )
2017
24
Expression of small leucine-rich extracellular matrix proteoglycans biglycan and lumican reveals oral lichen planus malignant potential. ( 28779221 )
2017
25
TRPA1 receptor is upregulated in human oral lichen planus. ( 27718297 )
2017
26
DEFB1 polymorphisms and salivary hBD-1 concentration in Oral Lichen Planus patients and healthy subjects. ( 27770642 )
2017
27
IL-17A polymorphism and elevated IL-17A serum levels are associated with oral lichen planus. ( 28741807 )
2017
28
Direct Immunofluorescence as a Helpful Tool for the Differential Diagnosis of Oral Lichen Planus and Oral Lichenoid Lesions. ( 29293127 )
2017
29
Expression of survivin and p53 in oral lichen planus, lichenoid reaction and lichenoid dysplasia: An immunohistochemical study. ( 29391729 )
2017
30
Scoring systems for Oral Lichen Planus used by differently experienced raters. ( 28809373 )
2017
31
Efficacy of steroidal vs non-steroidal agents in oral lichen planus: a randomised, open-label study. ( 27917729 )
2017
32
Salivary levels of interleukin-8 in oral lichen planus and diabetic patients: A biochemical study. ( 28702063 )
2017
33
Mucin 5B in saliva and serum of patients with oral lichen planus. ( 28935947 )
2017
34
Identification of AgNORs and cytopathological changes in oral lichen planus lesions. ( 27916273 )
2017
35
Medical treatments for pregnant patients with oral lichen planus. ( 27826983 )
2017
36
Association between -1082a88A/G polymorphism in IL-10 and oral lichen planus: A meta-analysis. ( 28094099 )
2017
37
Interventions for the management of Oral lichen planus: A review of the conventional and novel therapies. ( 28055124 )
2017
38
Using the BITOLA system to identify candidate molecules in the interaction between oral lichen planus and depression. ( 27913255 )
2017
39
TRPA1 may contribute to the exacerbation of oral lichen planus through Koebner phenomenon. ( 28067971 )
2017
40
The microbiology of oral lichen planus: Is microbial infection the cause of oral lichen planus? ( 28869787 )
2017
41
Salivary and serum levels of tumor necrosis factor-alpha in oral lichen planus: a systematic review and meta-analysis study. ( 28823317 )
2017
42
Evaluation of oxidative stress markers in oral lichen planus. ( 29391713 )
2017
43
The relationship between levels of salivary and serum interleukin-6 and oral lichen planus: A systematic review and meta-analysis. ( 28712412 )
2017
44
Integrative analysis of mRNA and miRNA expression profiles in oral lichen planus: preliminary results. ( 28743667 )
2017
45
Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution. ( 29354593 )
2017
46
Primary extramedullary plasmacytoma mimicking oral lichen planus. ( 28944756 )
2017
47
Evidence of genetic factors involved in oral lichen planus pathogenesis. ( 28736881 )
2017
48
Association between the clinical severity of oral lichen planus and anti-TPO level in thyroid patients. ( 28076499 )
2017
49
Letter to the Editor: Development of proliferative verrucous leukoplakia (PVL) in oral lichen planus: Is it not a clinical spectrum of PVL? ( 28160592 )
2017
50
Efficacy of low-level laser therapy compared to steroid therapy in the treatment of oral lichen planus: A systematic review. ( 28766756 )
2017

Variations for Oral Lichen Planus

Expression for Oral Lichen Planus

Search GEO for disease gene expression data for Oral Lichen Planus.

Pathways for Oral Lichen Planus

Pathways related to Oral Lichen Planus according to GeneCards Suite gene sharing:

(show all 34)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.89 CASP3 CCL5 CCR5 CD58 HSPA8 ICAM1
2
Show member pathways
13.26 BAX CASP3 CCL5 CCR5 CXCR3 IL1A
3
Show member pathways
13.1 BAX CASP3 CCL5 CCR5 CXCR3 IL1A
4
Show member pathways
13.03 CASP3 CCL5 CCR5 HSPA8 ICAM1 IL1A
5
Show member pathways
12.72 CASP3 HSPA8 HSPD1 ICAM1 IL1A
6
Show member pathways
12.67 CASP3 CCL5 HSPA8 ICAM1 IL1A
7
Show member pathways
12.6 CASP3 ICAM1 MMP1 TIMP2 VCAM1
8
Show member pathways
12.43 BAX CASP3 CCR5 ICAM1
9
Show member pathways
12.11 CASP3 CCR5 HSPA8 IL1A
10 12.08 BAX CASP3 HSPD1 IL1A
11 12.02 BAX CASP3 MMP1
12 11.99 CD58 ICAM1 VCAM1
13 11.96 ICAM1 IL1A VCAM1
14
Show member pathways
11.95 CCL5 CCR5 CXCR3 ICAM1 MMP1 VCAM1
15
Show member pathways
11.91 BAX CASP3 TP63
16 11.88 CASP3 ICAM1 IL1A
17
Show member pathways
11.86 CCL5 CCR5 CXCR3
18 11.77 CASP3 CCL5 ICAM1 VCAM1
19
Show member pathways
11.7 BAX CASP3 VCAM1
20 11.69 BAX ICAM1 MMP1
21 11.66 CCL5 ICAM1 IL1A MMP1
22 11.47 CASP3 HSPA8 HSPD1
23 11.41 HSPA8 ICAM1 IL1A MMP1 VCAM1
24
Show member pathways
11.36 ICAM1 IL1A MMP1 VCAM1
25 11.35 BAX CASP3 MMP1
26 11.24 CCL5 MMP1 TIMP2
27 11.18 BAX CCL5 IL1A
28 11.15 CCL5 CCR5 ICAM1 IL1A
29 11.06 ICAM1 TIMP2
30 11.02 BAX CASP3
31 11.02 BAX CASP3 ICAM1 IL1A VCAM1
32
Show member pathways
10.99 BAX TP63
33 10.86 CCL5 MMP1
34 10.83 ICAM1 VCAM1

GO Terms for Oral Lichen Planus

Cellular components related to Oral Lichen Planus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 CCL5 HSPA8 HSPD1 ICAM1 IL1A TIMP2
2 external side of plasma membrane GO:0009897 9.46 CCR5 CXCR3 ICAM1 VCAM1
3 extracellular matrix GO:0031012 9.35 HSPA8 HSPD1 ICAM1 MMP1 TIMP2
4 cell surface GO:0009986 9.17 CCR5 CD58 CXCR3 HSPD1 ICAM1 TIMP2

Biological processes related to Oral Lichen Planus according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.97 BAX CASP3 CXCR3 IL1A TP63
2 inflammatory response GO:0006954 9.91 CCL5 CCR5 CXCR3 IL1A
3 chemotaxis GO:0006935 9.81 CCL5 CCR5 CXCR3
4 cell-cell adhesion GO:0098609 9.78 CD58 ICAM1 VCAM1
5 cellular response to interferon-gamma GO:0071346 9.72 CCL5 CD58 ICAM1
6 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.71 BAX CASP3 HSPD1
7 chemokine-mediated signaling pathway GO:0070098 9.69 CCL5 CCR5 CXCR3
8 regulation of neuron apoptotic process GO:0043523 9.63 BAX TP63
9 response to X-ray GO:0010165 9.63 CASP3 TP63
10 apoptotic mitochondrial changes GO:0008637 9.62 BAX HSPD1
11 B cell homeostasis GO:0001782 9.62 BAX CASP3
12 response to ionizing radiation GO:0010212 9.61 BAX ICAM1 VCAM1
13 dendritic cell chemotaxis GO:0002407 9.6 CCL5 CCR5
14 response to copper ion GO:0046688 9.59 ICAM1 IL1A
15 positive regulation of protein oligomerization GO:0032461 9.58 BAX MMP1
16 protein refolding GO:0042026 9.58 HSPA8 HSPD1
17 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 9.56 BAX TP63
18 cellular response to tumor necrosis factor GO:0071356 9.56 CCL5 CD58 ICAM1 VCAM1
19 neuron apoptotic process GO:0051402 9.54 BAX CASP3 TP63
20 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 9.52 BAX CASP3
21 cellular response to organic substance GO:0071310 9.5 BAX CASP3 ICAM1
22 ectopic germ cell programmed cell death GO:0035234 9.49 BAX IL1A
23 negative regulation of macrophage apoptotic process GO:2000110 9.48 CCL5 CCR5
24 membrane to membrane docking GO:0022614 9.46 ICAM1 VCAM1
25 adhesion of symbiont to host GO:0044406 9.4 HSPD1 ICAM1
26 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.33 BAX CASP3 IL1A
27 viral process GO:0016032 9.17 BAX CCR5 HSPA8 HSPD1 ICAM1 MMP1
28 leukocyte cell-cell adhesion GO:0007159 9.13 CCL5 ICAM1 VCAM1

Molecular functions related to Oral Lichen Planus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine receptor activity GO:0004950 8.96 CCR5 CXCR3
2 integrin binding GO:0005178 8.8 ICAM1 TIMP2 VCAM1

Sources for Oral Lichen Planus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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