MCID: ORL013
MIFTS: 46

Oral Lichen Planus

Categories: Rare diseases, Oral diseases

Aliases & Classifications for Oral Lichen Planus

MalaCards integrated aliases for Oral Lichen Planus:

Name: Oral Lichen Planus 50
Oral Lichenoid Lesions 50
Lichen Planus, Oral 69
Lichen Planus Oral 52

Classifications:



Summaries for Oral Lichen Planus

NIH Rare Diseases : 50 oral lichen planus is a inflammatory condition that affects the inside of the mouth.  signs and symptoms include patches of fine white lines and dots most commonly in the inside of the cheeks, gums, and/or tongue. most people with lichen planus experience no to few symptoms, others may have painful sores or ulcers in the mouth. severe lichen planus slightly increases the risk for oral cancer. oral lichen planus may occur alone or in combination with other skin forms of lichen planus. last updated: 7/20/2011

MalaCards based summary : Oral Lichen Planus, also known as oral lichenoid lesions, is related to lichen planus and lymphomatous thyroiditis, and has symptoms including oral manifestations An important gene associated with Oral Lichen Planus is TP63 (Tumor Protein P63), and among its related pathways/superpathways are Innate Immune System and Integrin Pathway. The drugs Benzocaine and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include tongue, skin and t cells, and related phenotypes are Decreased influenza A H1N1 (A/Hamburg/04/2009) virus numbers and cardiovascular system

Related Diseases for Oral Lichen Planus

Diseases related to Oral Lichen Planus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 116)
id Related Disease Score Top Affiliating Genes
1 lichen planus 11.2
2 lymphomatous thyroiditis 10.7 ICAM1 VCAM1
3 hodgkin's lymphoma, nodular sclerosis 10.6 CASP3 ICAM1
4 benign infantile focal epilepsy with midline spikes and wave during sleep 10.6 CCL5 CCR5
5 marginal corneal ulcer 10.6 ICAM1 VCAM1
6 dysphagia 10.5 CCL5 ICAM1 VCAM1
7 dentin dysplasia 10.5 CCL5 ICAM1 VCAM1
8 hepatitis 10.5
9 hidradenitis suppurativa 10.5 CCL5 HSPD1
10 hepatitis c 10.5
11 angiokeratoma 10.5 CCR5 ICAM1 VCAM1
12 squamous cell carcinoma 10.5
13 hyperpigmentation of eyelid 10.5 CCL5 ICAM1 VCAM1
14 inferolateral myocardial infarct 10.5 ICAM1 VCAM1
15 benign secondary hypertension 10.4 CCR5 ICAM1 VCAM1
16 iida kannari syndrome 10.4 CASP3 CCL5 IL1A
17 leukoplakia 10.4
18 histoplasmosis pericarditis 10.4 ICAM1 IL1A VCAM1
19 malignant epithelial mesothelioma 10.4 CCL5 ICAM1 VCAM1
20 hepatitis c virus 10.4
21 oral squamous cell carcinoma 10.4
22 xanthogranulomatous cholecystitis 10.4 CASP3 MMP1
23 gingivitis 10.3
24 optic atrophy 7 10.3 IL1A MMP1
25 oppositional defiant disorder 10.3 ICAM1 MMP1 VCAM1
26 psychosexual disorder 10.3 ICAM1 MMP1 VCAM1
27 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 10.3 CCL5 IL1A
28 intra-abdominal lymph node mast cell malignancy 10.3 ICAM1 MMP1 VCAM1
29 lipoid nephrosis 10.3 ICAM1 IL1A MMP1
30 synovium cancer 10.3 ICAM1 MMP1 VCAM1
31 myelophthisic anemia 10.3 HSPD1 ICAM1 VCAM1
32 cannabis abuse 10.3 CCL5 CXCR3 ICAM1
33 ragweed sensitivity 10.3 CCL5 ICAM1 IL1A VCAM1
34 viljoen kallis voges syndrome 10.2 CCL5 CXCR3 ICAM1
35 periodontitis 10.2
36 oral leukoplakia 10.2
37 atypical lichen myxedematosus 10.2 CCR5 CXCR3
38 myofascial pain syndrome 10.2 CCL5 CXCR3 IL1A
39 oropharyngeal cancer, childhood 10.2 CCL5 CCR5 CXCR3
40 heart lymphoma 10.2 CD58 ICAM1 VCAM1
41 mucositis 10.2
42 benign eccrine breast spiradenoma 10.2 CASP3 CXCR3 ICAM1
43 inflammatory bowel disease 3 10.2 CCL5 CXCR3 ICAM1
44 moved to 244450 10.2 CD58 ICAM1 VCAM1
45 liver disease 10.2 ICAM1 IL1A TP63 VCAM1
46 cerebellar disease 10.2 CXCR3 ICAM1 IL1A
47 thyroiditis 10.1
48 pemphigus 10.1
49 stomatitis 10.1
50 esophageal candidiasis 10.1 CXCR3 ICAM1 IL1A

Graphical network of the top 20 diseases related to Oral Lichen Planus:



Diseases related to Oral Lichen Planus

Symptoms & Phenotypes for Oral Lichen Planus

UMLS symptoms related to Oral Lichen Planus:


oral manifestations

GenomeRNAi Phenotypes related to Oral Lichen Planus according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased influenza A H1N1 (A/Hamburg/04/2009) virus numbers GR00195-A-3 8.8 CD58 HSPD1 IL1A

MGI Mouse Phenotypes related to Oral Lichen Planus:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.97 IL1A CASP3 TIMP2 CCR5 TP63 VCAM1
2 hematopoietic system MP:0005397 9.97 IL1A CASP3 TIMP2 CCL5 CCR5 VCAM1
3 homeostasis/metabolism MP:0005376 9.96 IL1A CASP3 MMP1 TIMP2 CCR5 TP63
4 immune system MP:0005387 9.9 CASP3 MMP1 TIMP2 CCL5 CCR5 TP63
5 muscle MP:0005369 9.43 BAX CASP3 CCR5 TP63 HSPD1 ICAM1
6 neoplasm MP:0002006 9.17 MMP1 CCR5 TP63 CXCR3 ICAM1 BAX

Drugs & Therapeutics for Oral Lichen Planus

Drugs for Oral Lichen Planus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 122)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
2
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 124-94-7 31307
3
Pimecrolimus Approved, Investigational Phase 4,Phase 3,Phase 2 137071-32-0 6447131 17753757
4
Tacrolimus Approved, Investigational Phase 4,Phase 2 104987-11-3 445643 439492
5
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
6
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
7
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Early Phase 1 22916-47-8 4189
9 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1
10
Chitosan Approved, Nutraceutical Phase 4 9012-76-4 71853
11
Glucosamine Approved, Nutraceutical Phase 4 3416-24-8 439213
12
Lycopene Approved, Nutraceutical Phase 4,Phase 2 502-65-8 446925
13
Lactitol Investigational Phase 4 585-86-4 3871
14 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
15 glucocorticoids Phase 4,Phase 3,Phase 2,Early Phase 1
16 Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
17 Hormones Phase 4,Phase 3,Phase 2,Early Phase 1
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
19 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Early Phase 1
20 triamcinolone acetonide Phase 4,Phase 3,Phase 2,Early Phase 1
21 Triamcinolone diacetate Phase 4,Phase 3,Phase 2,Early Phase 1
22 Triamcinolone hexacetonide Phase 4,Phase 3,Phase 2,Early Phase 1
23 Antiemetics Phase 4,Phase 3,Phase 2,Early Phase 1
24 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Early Phase 1
25 Antioxidants Phase 4,Phase 3,Phase 2,Phase 1
26 Autonomic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
27 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Early Phase 1
28 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Early Phase 1
29 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
30 Analgesics Phase 4,Phase 3,Phase 2
31 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
32 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2
33 Antirheumatic Agents Phase 4,Phase 3,Phase 2
34 Calcineurin Inhibitors Phase 4,Phase 3,Phase 2
35 Dermatologic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
36 Carotenoids Phase 4,Phase 2
37 Methylprednisolone acetate Phase 4,Phase 2
38 Methylprednisolone Hemisuccinate Phase 4,Phase 2
39 Neuroprotective Agents Phase 4
40 Prednisolone acetate Phase 4,Phase 2
41 Prednisolone hemisuccinate Phase 4,Phase 2
42 Prednisolone phosphate Phase 4,Phase 2
43 Radiation-Protective Agents Phase 4,Phase 2
44 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
45 Antifungal Agents Phase 4,Phase 3,Early Phase 1
46 Betamethasone benzoate Phase 4,Phase 3,Phase 2
47 Betamethasone sodium phosphate Phase 4,Phase 3,Phase 2
48 Betamethasone Valerate Phase 4,Phase 3,Phase 2 2152-44-5
49 Betamethasone-17,21-dipropionate Phase 4,Phase 3,Phase 2
50 Respiratory System Agents Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 54)

id Name Status NCT ID Phase Drugs
1 Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus Completed NCT02858297 Phase 4 Glucosamine sulfate;triamcinolone acetonide
2 A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus Completed NCT02587117 Phase 4 lycopene;Prednisolone
3 Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus Completed NCT02443311 Phase 4 Pimecrolimus 1% cream;Betamethasone 17-valerate 0.1% cream
4 The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus Unknown status NCT01083420 Phase 3 Minocycline;Dexamethasone
5 Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus Completed NCT02329600 Phase 3 green tea tablets (Green tea extract 5:1) 200 mg;Triamcinolone Acetonide
6 Chamaemelum Nobile 2% Versus Placebo Topic Gel to Treat Oral Lichen Planus Completed NCT02421770 Phase 3
7 Efficacy of Elidel Cream on Erosive Oral Lichen Planus Completed NCT00130572 Phase 3 Pimecrolimus
8 Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen Terminated NCT01061853 Phase 3 TOPICAL SIROLIMUS (RAPAMUNE*);TOPICAL BETAMETHASONE 0.05%
9 A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus Unknown status NCT01524744 Phase 2 Pimecrolimus ointment;Adcortyl
10 Lichen Planus Mucosae at USZ, Efficacy of Oral Alitretinoin Unknown status NCT01538732 Phase 2 alitretinoin
11 Pilot Study of Apremilast (CC-10004) in the Treatment of Moderate to Severe Lichen Planus Unknown status NCT01041625 Phase 2 Apremilast (CC-10004)
12 A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus Completed NCT00525421 Phase 2 Curcuminoids;Placebo
13 Pimecrolimus Cream for Oral Lichen Planus Completed NCT00297037 Phase 2 Pimecrolimus 1% cream
14 Dexamethasone to Treat Oral Lichen Planus Completed NCT00111072 Phase 2 dexamethasone 0.01% solution
15 Cedar Honey in Oral Lichen Planus Completed NCT01974414 Phase 1, Phase 2 orally administered cedar honey
16 Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus Completed NCT02744378 Phase 2 Tacrolimus 0.1%;Clobetasol 0.05%
17 Efficacy of Purslane in Treatment of Oral Lichen Planus Completed NCT00746772 Phase 2 Purslane 235mg/day in one dosage;Placebo : one dosage
18 Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other Completed NCT00484250 Phase 2 metronidazole,doxycycline
19 Treatmant of Oral Lichen Planus With Lycopene Completed NCT00656214 Phase 2 Lycopene;Placebo
20 Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planus Completed NCT00102557 Phase 2 Hydroxychloroquine
21 Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus Completed NCT02453503 Phase 2 Licorice;Triamcinolone Acetonide
22 The Efficacy of Omega-3 in Treatment of Atrophic/Erosive Lichen Planus Completed NCT02106468 Phase 2 Prednisone tablet 5mg;Omega-3 soft capsules 1000 mg
23 Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases Completed NCT02920658 Phase 2 NAVS Naphthalan;0.05% Betamethasone dipropionate
24 Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus Recruiting NCT03026478 Phase 2 Betamethasone Dipropionate;Clobetasol Propionate
25 Serum Cortisol Levels in Patients With Anxiety and Depression With Symptomatic Oral Lichen Planus Recruiting NCT03011658 Phase 1, Phase 2
26 Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus Not yet recruiting NCT03293368 Phase 2 Triamcinolone Acetonide
27 Dexamethasone Solution for the Treatment of Oral Lichen Planus Not yet recruiting NCT02850601 Phase 2 Dexamethasone
28 A Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Curcuminoids in Oral Lichen Planus Terminated NCT00226174 Phase 2 Curcuminoids
29 Treatment of Oral Erosive Lichen Planus With Pimecrolimus Cream Terminated NCT00321750 Phase 2 1% pimecrolimus cream
30 Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain Terminated NCT01584947 Phase 2 Bupivacaine;Placebo
31 A Safety and Efficacy Study of Alefacept in the Treatment of Moderate to Severe Erosive Mucosal Lichen Planus Terminated NCT00135733 Phase 2 Amevive (Alefacept);Placebo
32 Free Soft Tissue Graft in Treatment of Oral Lichen Planus Unknown status NCT00737854 Phase 1
33 Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus Unknown status NCT01375101 Phase 1 placebo;Quercetin
34 Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus Unknown status NCT02276573
35 Incidence of Esophageal Lichen Planus in Patients With Known Oral Lichen Planus Unknown status NCT02532166
36 Expression of miRNa-138 and Cyclin D1 in Oral Mucosa of Patients With Oral Lichen Planus Completed NCT02834520
37 Impact of Continuous Defocused CO2 Laser Vaporisation on the Histological Malignant Transformation of Erosive Oral Lichen Planus in Patients Completed NCT02154607
38 The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus Completed NCT01743690 Nystatin;fluocinolone
39 The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2) Completed NCT03257228
40 Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral Cavity Completed NCT03026361
41 Safety and Effectiveness of Efalizumab to Treat Oral Lichen Planus Completed NCT00133107 efalizumab
42 Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy Completed NCT03031899
43 Biomarkers for Oral Cancer Completed NCT00341497
44 Evaluation and Treatment of Oral Soft Tissue Diseases Completed NCT00001601
45 Clinical Research Core Dental Screening Protocol Completed NCT00090818
46 Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions Completed NCT02323672
47 Treatment Modalities of Oral Lichen Planus Recruiting NCT03237533 Early Phase 1 Dexamethasone
48 Use of Injectable Platelet Rich Fibrin in Lichen Planus Recruiting NCT03265093 Corticosteroid
49 Tobacco Cessation Intervention Study for Oral Diseases Recruiting NCT02737176
50 Vaginal and Oral Microbiome Crosstalk Recruiting NCT02898818

Search NIH Clinical Center for Oral Lichen Planus

Genetic Tests for Oral Lichen Planus

Anatomical Context for Oral Lichen Planus

MalaCards organs/tissues related to Oral Lichen Planus:

39
Tongue, Skin, T Cells, Thyroid, Endothelial, Testes, Smooth Muscle

Publications for Oral Lichen Planus

Articles related to Oral Lichen Planus:

(show top 50) (show all 734)
id Title Authors Year
1
Primary extramedullary plasmacytoma mimicking oral lichen planus. ( 28944756 )
2017
2
DEFB1 polymorphisms and salivary hBD-1 concentration in Oral Lichen Planus patients and healthy subjects. ( 27770642 )
2017
3
IL-17A polymorphism and elevated IL-17A serum levels are associated with oral lichen planus. ( 28741807 )
2017
4
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma ( 28749626 )
2017
5
Incidence of Oral Lichen Planus in Perimenopausal Women: A Cross-sectional Study in Western Uttar Pradesh Population. ( 28706407 )
2017
6
Immune receptors CD40 and CD86 in oral keratinocytes and implications for oral lichen planus. ( 28904313 )
2017
7
Efficacy of steroidal vs non-steroidal agents in oral lichen planus: a randomised, open-label study. ( 27917729 )
2017
8
Semaphorin4D Drives CD8(+) T-Cell Lesional Trafficking in Oral Lichen Planus via CXCL9/CXCL10 Upregulations in OralA Keratinocytes. ( 28760660 )
2017
9
Association between -1082a88A/G polymorphism in IL-10 and oral lichen planus: A meta-analysis. ( 28094099 )
2017
10
Evidence of genetic factors involved in oral lichen planus pathogenesis. ( 28736881 )
2017
11
The relationship between levels of salivary and serum interleukin-6 and oral lichen planus: A systematic review and meta-analysis. ( 28712412 )
2017
12
TRPA1 may contribute to the exacerbation of oral lichen planus through Koebner phenomenon. ( 28067971 )
2017
13
Treatment of oral lichen planus using 308-nm excimer laser. ( 28833900 )
2017
14
Triggers of oral lichen planus flares and the potential role of trigger avoidance in disease management. ( 28732699 )
2017
15
Scoring systems for Oral Lichen Planus used by differently experienced raters. ( 28809373 )
2017
16
Salivary and serum levels of tumor necrosis factor-alpha in oral lichen planus: a systematic review and meta-analysis study. ( 28823317 )
2017
17
Integrative analysis of mRNA and miRNA expression profiles in oral lichen planus: preliminary results. ( 28743667 )
2017
18
Mucin 5B in saliva and serum of patients with oral lichen planus. ( 28935947 )
2017
19
Using the BITOLA system to identify candidate molecules in the interaction between oral lichen planus and depression. ( 27913255 )
2017
20
Identification of AgNORs and cytopathological changes in oral lichen planus lesions. ( 27916273 )
2017
21
Salivary levels of interleukin-8 in oral lichen planus and diabetic patients: A biochemical study. ( 28702063 )
2017
22
Expression of small leucine-rich extracellular matrix proteoglycans biglycan and lumican reveals oral lichen planus malignant potential. ( 28779221 )
2017
23
Efficacy of low-level laser therapy compared to steroid therapy in the treatment of oral lichen planus: A systematic review. ( 28766756 )
2017
24
Treatment of oral lichen planus. Systematic review and therapeutic guide. ( 28756997 )
2017
25
Interventions for the management of Oral lichen planus: A review of the conventional and novel therapies. ( 28055124 )
2017
26
Medical treatments for pregnant patients with oral lichen planus. ( 27826983 )
2017
27
The microbiology of oral lichen planus: Is microbial infection the cause of oral lichen planus? ( 28869787 )
2017
28
Association between the clinical severity of oral lichen planus and anti-TPO level in thyroid patients. ( 28076499 )
2017
29
Possible alternative therapies for oral lichen planus cases refractory to steroid therapies. ( 27068310 )
2016
30
CD1a+ dendritic cells in oral lichen planus and amalgam lichenoid reaction. ( 27086000 )
2016
31
Epidemiology of Oral Lichen Planus in a Cohort of South Indian Population: A Retrospective Study. ( 27051650 )
2016
32
Relation Between Periodontal Status and Pre-Cancerous Condition (Oral Lichen Planus): A Pilot Study. ( 27629852 )
2016
33
ALK1 expression in oral lichen planus: a possible relation to microvessel density. ( 26662187 )
2016
34
Image-based DNA ploidy analysis aids prediction of malignant transformation in oral lichen planus. ( 27084261 )
2016
35
Association of genetic polymorphisms in interferon-I^, interleukin-6 and transforming growth factor-I^1 gene with oral lichen planus susceptibility. ( 27544215 )
2016
36
Immunohistochemical Expression of Stromelysin-2 (St-2) In Patients with Oral Lichen Planus and Its Clinical Significance. ( 27840837 )
2016
37
The efficacy of Aloe Vera in management of oral lichen planus: a systematic review and meta-analysis. ( 28029732 )
2016
38
Oral lichen planus: therapy and phenotype. ( 27982545 )
2016
39
Oral candidiasis following steroid therapy for oral lichen planus. ( 26599999 )
2016
40
Clinical profile of 108 cases of oral lichen planus. ( 27021539 )
2016
41
The Magnitude of the Association between Human Papillomavirus and Oral Lichen Planus: A Meta-Analysis. ( 27571417 )
2016
42
Mucocutaneous Diseases: Oral Lichen Planus, Mucous Membrane Pemphigoid and Pemphigus Vulgaris. ( 28742296 )
2016
43
Molecular markers in oral lichen planus: A systematic review. ( 27194873 )
2016
44
Different Expression of MicroRNA-146a in Peripheral Blood CD4(+) T Cells and Lesions of Oral Lichen Planus. ( 26861135 )
2016
45
Food allergen-mediated exacerbations of oral lichen planus. ( 27663157 )
2016
46
A randomized triple-blind clinical trial to compare the effectiveness of topical triamcinolone acetonate (0.1%), clobetasol propionate (0.05%), and tacrolimus orabase (0.03%) in the management of oral lichen planus. ( 27829754 )
2016
47
miR-125b inhibits keratinocyte proliferation and promotes keratinocyte apoptosis in oral lichen planus by targeting MMP-2 expression through PI3K/Akt/mTOR pathway. ( 27133077 )
2016
48
To estimate the efficacy of 0.1% tacrolimus with Colgate Oraguard-B paste for the treatment of patients with symptomatic oral lichen planus. ( 27134451 )
2016
49
Filaggrin gene mutations and the distribution of filaggrin in oral mucosa of patients with oral lichen planus and healthy controls. ( 28000306 )
2016
50
Prevalence of Oral Lichen Planus in Diabetes Mellitus: a Meta-Analysis Study. ( 28077900 )
2016

Variations for Oral Lichen Planus

Expression for Oral Lichen Planus

Search GEO for disease gene expression data for Oral Lichen Planus.

Pathways for Oral Lichen Planus

Pathways related to Oral Lichen Planus according to GeneCards Suite gene sharing:

(show all 33)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.89 CASP3 CCL5 CCR5 CD58 HSPA8 ICAM1
2
Show member pathways
13.26 CASP3 CCL5 CCR5 CXCR3 ICAM1 MMP1
3
Show member pathways
13.25 BAX CASP3 CCL5 CCR5 CXCR3 IL1A
4
Show member pathways
13.09 BAX CASP3 CCL5 CCR5 CXCR3 IL1A
5
Show member pathways
13.03 CASP3 CCL5 CCR5 HSPA8 ICAM1 IL1A
6
Show member pathways
12.72 CASP3 HSPA8 HSPD1 ICAM1 IL1A
7
Show member pathways
12.66 CASP3 CCL5 HSPA8 ICAM1 IL1A
8
Show member pathways
12.59 CASP3 ICAM1 MMP1 TIMP2 VCAM1
9
Show member pathways
12.1 CASP3 CCR5 HSPA8 IL1A
10 12.06 BAX CASP3 HSPD1 IL1A
11 12.02 BAX CASP3 MMP1
12 11.98 CD58 ICAM1 VCAM1
13 11.96 ICAM1 IL1A VCAM1
14
Show member pathways
11.9 BAX CASP3 TP63
15 11.88 CASP3 ICAM1 IL1A
16
Show member pathways
11.88 CCL5 CCR5 CXCR3
17 11.74 CASP3 CCL5 ICAM1 VCAM1
18
Show member pathways
11.7 BAX CASP3 VCAM1
19 11.69 BAX ICAM1 MMP1
20 11.62 CCL5 ICAM1 IL1A MMP1
21 11.46 CASP3 HSPA8 HSPD1
22 11.41 HSPA8 ICAM1 IL1A MMP1 VCAM1
23
Show member pathways
11.36 ICAM1 IL1A MMP1 VCAM1
24 11.33 BAX CASP3 MMP1
25 11.22 CCL5 MMP1 TIMP2
26 11.15 BAX CCL5 IL1A
27 11.15 CCL5 CCR5 ICAM1 IL1A
28 11.06 ICAM1 TIMP2
29 11.02 BAX CASP3 ICAM1 IL1A VCAM1
30 11.01 BAX CASP3
31
Show member pathways
10.98 BAX TP63
32 10.86 CCL5 MMP1
33 10.82 ICAM1 VCAM1

GO Terms for Oral Lichen Planus

Cellular components related to Oral Lichen Planus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 CCL5 HSPA8 HSPD1 ICAM1 IL1A TIMP2
2 external side of plasma membrane GO:0009897 9.46 CCR5 CXCR3 ICAM1 VCAM1
3 extracellular matrix GO:0031012 9.26 HSPA8 HSPD1 MMP1 TIMP2
4 cell surface GO:0009986 9.17 CCR5 CD58 CXCR3 HSPD1 ICAM1 TIMP2

Biological processes related to Oral Lichen Planus according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.97 BAX CASP3 CXCR3 IL1A TP63
2 inflammatory response GO:0006954 9.91 CCL5 CCR5 CXCR3 IL1A
3 single organismal cell-cell adhesion GO:0016337 9.73 CD58 ICAM1 VCAM1
4 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.71 BAX CASP3 HSPD1
5 chemokine-mediated signaling pathway GO:0070098 9.69 CCL5 CCR5 CXCR3
6 cellular response to interferon-gamma GO:0071346 9.65 CCL5 CD58 ICAM1
7 regulation of neuron apoptotic process GO:0043523 9.63 BAX TP63
8 response to X-ray GO:0010165 9.62 CASP3 TP63
9 apoptotic mitochondrial changes GO:0008637 9.62 BAX HSPD1
10 B cell homeostasis GO:0001782 9.61 BAX CASP3
11 response to ionizing radiation GO:0010212 9.61 BAX ICAM1 VCAM1
12 dendritic cell chemotaxis GO:0002407 9.6 CCL5 CCR5
13 response to copper ion GO:0046688 9.59 ICAM1 IL1A
14 positive regulation of protein oligomerization GO:0032461 9.58 BAX MMP1
15 protein refolding GO:0042026 9.58 HSPA8 HSPD1
16 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 9.55 BAX TP63
17 neuron apoptotic process GO:0051402 9.54 BAX CASP3 TP63
18 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 9.52 BAX CASP3
19 cellular response to organic substance GO:0071310 9.5 BAX CASP3 ICAM1
20 ectopic germ cell programmed cell death GO:0035234 9.49 BAX IL1A
21 membrane to membrane docking GO:0022614 9.46 ICAM1 VCAM1
22 cellular response to tumor necrosis factor GO:0071356 9.46 CCL5 CD58 ICAM1 VCAM1
23 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.43 BAX CASP3 IL1A
24 adhesion of symbiont to host GO:0044406 9.4 HSPD1 ICAM1
25 viral process GO:0016032 9.17 BAX CCR5 HSPA8 HSPD1 ICAM1 MMP1
26 leukocyte cell-cell adhesion GO:0007159 9.13 CCL5 ICAM1 VCAM1

Molecular functions related to Oral Lichen Planus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine receptor activity GO:0004950 8.96 CCR5 CXCR3
2 integrin binding GO:0005178 8.8 ICAM1 TIMP2 VCAM1

Sources for Oral Lichen Planus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
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