MCID: ORL006
MIFTS: 16

Oral Mucosa Leukoplakia

Categories: Oral diseases

Aliases & Classifications for Oral Mucosa Leukoplakia

MalaCards integrated aliases for Oral Mucosa Leukoplakia:

Name: Oral Mucosa Leukoplakia 12 14
Leukoplakia of Buccal Mucosa 69
Leukoplakia, Oral 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9655
ICD10 32 K13.2 K13.21
ICD9CM 34 528.6

Summaries for Oral Mucosa Leukoplakia

MalaCards based summary : Oral Mucosa Leukoplakia, also known as leukoplakia of buccal mucosa, is related to hellp syndrome and asthma. An important gene associated with Oral Mucosa Leukoplakia is GSTP1 (Glutathione S-Transferase Pi 1), and among its related pathways/superpathways is Fluid shear stress and atherosclerosis. Affiliated tissues include tongue, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Oral Mucosa Leukoplakia

Diseases related to Oral Mucosa Leukoplakia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hellp syndrome 9.5 EDN1 GSTP1
2 asthma 9.4 EDN1 GSTP1

Symptoms & Phenotypes for Oral Mucosa Leukoplakia

GenomeRNAi Phenotypes related to Oral Mucosa Leukoplakia according to GeneCards Suite gene sharing:

25 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.4 GSTP1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.4 GSTP1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-133 9.4 GSTP1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.4 GSTP1 EDN1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.4 EDN1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-22 9.4 GSTP1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.4 EDN1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.4 EDN1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.4 EDN1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.4 EDN1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.4 GSTP1

Drugs & Therapeutics for Oral Mucosa Leukoplakia

Search Clinical Trials , NIH Clinical Center for Oral Mucosa Leukoplakia

Genetic Tests for Oral Mucosa Leukoplakia

Anatomical Context for Oral Mucosa Leukoplakia

MalaCards organs/tissues related to Oral Mucosa Leukoplakia:

38
Tongue

Publications for Oral Mucosa Leukoplakia

Articles related to Oral Mucosa Leukoplakia:

# Title Authors Year
1
Leukoplakia of buccal mucosa with transformation into spindle cell carcinoma: A rare case report. ( 28479698 )
2017

Variations for Oral Mucosa Leukoplakia

Expression for Oral Mucosa Leukoplakia

Search GEO for disease gene expression data for Oral Mucosa Leukoplakia.

Pathways for Oral Mucosa Leukoplakia

Pathways related to Oral Mucosa Leukoplakia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.77 EDN1 GSTP1

GO Terms for Oral Mucosa Leukoplakia

Biological processes related to Oral Mucosa Leukoplakia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to amino acid GO:0043200 9.16 EDN1 GSTP1
2 cellular response to glucocorticoid stimulus GO:0071385 8.96 EDN1 GSTP1
3 negative regulation of nitric-oxide synthase biosynthetic process GO:0051771 8.62 EDN1 GSTP1

Sources for Oral Mucosa Leukoplakia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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