MCID: ORL015
MIFTS: 26

Oral Squamous Cell Carcinoma malady

Oral diseases, Cancer diseases categories

Summaries for Oral Squamous Cell Carcinoma

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32MalaCards
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MalaCards: Oral Squamous Cell Carcinoma is related to squamous cell carcinoma and lichen planus. An important gene associated with Oral Squamous Cell Carcinoma is HRAS (Harvey rat sarcoma viral oncogene homolog), and among its related pathways is MicroRNAs in cancer. The compounds paraffin and progesterone have been mentioned in the context of this disorder.

Aliases & Classifications for Oral Squamous Cell Carcinoma

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42NIH Rare Diseases
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Oral diseases


Aliases & Descriptions:

oral squamous cell carcinoma 42


Related Diseases for Oral Squamous Cell Carcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Oral Squamous Cell Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 85)
idRelated DiseaseScoreTop Affiliating Genes
1squamous cell carcinoma32.6DEFB4A, PDPN, VEGFC, MAGEA1, NME1, SERPINB5
2lichen planus31.1DEFB4A
3transitional cell carcinoma30.9NME1, KRT19, VEGFC
4melanoma30.8PDPN, MAGEA1, VEGFC, MAGED4B, MAGEA6, HRAS
5esophageal cancer30.5NME1, MAGEA1, VEGFC
6oral candidiasis30.4DEFB4A
7adenocarcinoma30.2SERPINB5, VEGFC, MAGEA1, HRAS, NME1, PDPN
8sarcoma30.2SERPINB5, MAGEA1, HRAS
9cervical squamous cell carcinoma10.7
10cervicitis10.7
11bone carcinoma10.7
12verrucous carcinoma10.7
13oral submucous fibrosis10.6
14squamous cell papilloma10.6
15in situ carcinoma10.6
16papilloma10.6
17small cell carcinoma10.5
18keratinizing squamous cell carcinoma10.5
19parathyroid carcinoma10.4
20basal cell carcinoma10.4
21eosinophilia10.4
22esophagitis10.4
23thrombocytosis10.3
24adenoid squamous cell carcinoma10.3
25colon squamous cell carcinoma10.3
26oral mucosa leukoplakia10.3
27trichinosis10.3
28hypercalcemia10.3
29adenoid cystic carcinoma10.3
30large cell carcinoma10.3
31adenoiditis10.3
32candidiasis10.3
33keratosis10.3
34myiasis10.3
35crohn's disease10.2
36cardiac tamponade10.2
37bullous pemphigoid10.2
38carotid stenosis10.2
39dyskeratosis congenita10.2
40keratosis follicularis10.2
41microcephaly10.2
42intussusception10.2
43tonsillitis10.2
44paracoccidioidomycosis10.2
45extramedullary plasmacytoma10.2
46cheilitis10.2
47colonic disease10.2
48conjunctivitis10.2
49herpes simplex10.2
50lip cancer10.2

Graphical network of the top 20 diseases related to Oral Squamous Cell Carcinoma:



Diseases related to oral squamous cell carcinoma

Clinical Features for Oral Squamous Cell Carcinoma

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Drugs & Therapeutics for Oral Squamous Cell Carcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Oral Squamous Cell Carcinoma

Drug clinical trials:

Search ClinicalTrials for Oral Squamous Cell Carcinoma

Search NIH Clinical Center for Oral Squamous Cell Carcinoma

Search CenterWatch for Oral Squamous Cell Carcinoma

Genetic Tests for Oral Squamous Cell Carcinoma

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Anatomical Context for Oral Squamous Cell Carcinoma

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Animal Models for Oral Squamous Cell Carcinoma or affiliated genes

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Publications for Oral Squamous Cell Carcinoma

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Genetic Variations for Oral Squamous Cell Carcinoma

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Expression for genes affiliated with Oral Squamous Cell Carcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Oral Squamous Cell Carcinoma

Search GEO for disease gene expression data for Oral Squamous Cell Carcinoma.

Pathways for genes affiliated with Oral Squamous Cell Carcinoma

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29KEGG
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Pathways related to Oral Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
111.2SERPINB5, HRAS, MIR124-2, MIR124-1, MIR124-3

Compounds for genes affiliated with Oral Squamous Cell Carcinoma

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Sources:
44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Oral Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1paraffin4411.9SERPINB5, PDPN, DEFB4A, VEGFC, MAGEA1, HRAS
2progesterone44 59 28 11 2415.7DEFB103B, DEFB4A, VEGFC, HRAS, NME1, KRT19
3steroid4411.5DEFB103B, DEFB4A, HRAS, NME1, KRT19, SERPINB5
4vegf4411.5PDPN, VEGFC, HRAS, NME1, KRT19, SERPINB5
5estrogen4411.3DEFB4A, VEGFC, HRAS, NME1, KRT19, SERPINB5
6p0024411.3DEFB4A, NME1, KRT19, SERPINB5
7glyceraldehyde 3-phosphate4411.2KRT19, NME1, VEGFC, DEFB4A
8matrigel4411.1VEGFC, NME1, KRT19, SERPINB5
9estradiol44 11 2412.6VEGFC
10hbd24410.5DEFB4A, DEFB103B

GO Terms for genes affiliated with Oral Squamous Cell Carcinoma

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16Gene Ontology
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Biological processes related to Oral Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of epithelial cell proliferationGO:05067910.9NME1, HRAS, VEGFC

Products for genes affiliated with Oral Squamous Cell Carcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Oral Squamous Cell Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet