MCID: ORL015
MIFTS: 36

Oral Squamous Cell Carcinoma malady

Rare diseases, Cancer diseases, Oral diseases categories
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Summaries for Oral Squamous Cell Carcinoma

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33MalaCards
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MalaCards: Oral Squamous Cell Carcinoma is related to oral cancer and endotheliitis. An important gene associated with Oral Squamous Cell Carcinoma is HRAS (Harvey rat sarcoma viral oncogene homolog), and among its related pathways are miRNAs involved in DDR and MicroRNAs in cancer. Affiliated tissues include lymph node, endothelial and bone.

Aliases & Classifications for Oral Squamous Cell Carcinoma

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8Disease Ontology, 43NIH Rare Diseases
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Oral diseases


Aliases & Descriptions:

oral squamous cell carcinoma 8 43


External Ids:

Disease Ontology8 DOID:0050866

Related Diseases for Oral Squamous Cell Carcinoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Oral Squamous Cell Carcinoma:



Diseases related to oral squamous cell carcinoma

Symptoms for Oral Squamous Cell Carcinoma

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Drugs & Therapeutics for Oral Squamous Cell Carcinoma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Oral Squamous Cell Carcinoma

Search NIH Clinical Center for Oral Squamous Cell Carcinoma

Genetic Tests for Oral Squamous Cell Carcinoma

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Anatomical Context for Oral Squamous Cell Carcinoma

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33MalaCards
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MalaCards organs/tissues related to Oral Squamous Cell Carcinoma:

33
Lymph node, Endothelial, Bone, T cells, Testes, Bone marrow, Colon, B cells, Tonsil, Nk cells, Placenta, Skin, Lung, Spleen, Tongue, Hypothalamus

Animal Models for Oral Squamous Cell Carcinoma or affiliated genes

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Publications for Oral Squamous Cell Carcinoma

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52PubMed
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Articles related to Oral Squamous Cell Carcinoma:

(show top 50)    (show all 1595)
idTitleAuthorsYear
1
Role of EZH2 in oral squamous cell carcinoma carcinogenesis. (24424512)
2014
2
Lack of Evidence for Predictive and Prognostic Value of Cyclin D1 Gene Polymorphism CCND1 G870A for Oral Squamous Cell Carcinoma. (24403468)
2014
3
The combination of silencing BAG3 and inhibition of the JNK pathway enhances hyperthermia sensitivity in human oral squamous cell carcinoma cells. (23395971)
2013
4
Stromal myofibroblasts in nonmetastatic and metastatic oral squamous cell carcinoma: An immunohistochemical study. (24250077)
2013
5
High interstitial fluid pressure promotes tumor cell proliferation and invasion in oral squamous cell carcinoma. (24043259)
2013
6
Analysis of CD8+ and CD4+ Cells in Oral Squamous Cell Carcinoma and Their Association With Lymph Node Metastasis and Histologic Grade of Malignancy. (23702647)
2013
7
SOX4 expression is closely associated with differentiation and lymph node metastasis in oral squamous cell carcinoma. (24030531)
2013
8
Correlation of P53 and granzyme B expression in oral squamous cell carcinoma with clinicopathologic findings. (23981150)
2013
9
Combined zoledronic acid and meloxicam reduced bone loss and tumour growth in an orthotopic mouse model of bone-invasive oral squamous cell carcinoma. (23651067)
2013
10
Accumulation of inactive p53 protein in oral squamous cell carcinoma: stabilization by protein interaction. (23331420)
2013
11
DEFENSINS: potent biomarkers in oral squamous cell carcinoma. (22763243)
2012
12
Expression of CA-IX is associated with advanced stage tumors and poor survival in oral squamous cell carcinoma patients. (22486898)
2012
13
Jun activation domain-binding protein 1 expression in oral squamous cell carcinomas inversely correlates with the cell cycle inhibitor p27. (22311264)
2012
14
HOXB7 expression is a prognostic factor for oral squamous cell carcinoma. (22239410)
2012
15
Retrospective Study of Selective Submandibular Neck Dissection versus Radical Neck Dissection for N0 or N1 Necks in Level I Patients with Oral Squamous Cell Carcinoma. (22690218)
2012
16
A study on histological grading of oral squamous cell carcinoma and its co-relationship with regional metastasis. (22529575)
2011
17
Increased I9Np63 expression is predictive of malignant transformation in oral epithelial dysplasia and poor prognosis in oral squamous cell carcinoma. (21833468)
2011
18
Overexpression of a chromatin remodeling factor, RSF-1/HBXAP, correlates with aggressive oral squamous cell carcinoma. (21514451)
2011
19
Primary tumor induces sentinel lymph node lymphangiogenesis in oral squamous cell carcinoma. (20308006)
2010
20
Multiple genetic copy number alterations in oral squamous cell carcinoma: study of MYC, TP53, CCDN1, EGFR and ERBB2 status in primary and metastatic tumours. (20662834)
2010
21
Correlation between the expression of cytokeratin-18-mRNA and invasion and metastasis of oral squamous cell carcinoma]. (19575986)
2009
22
Loss of human beta-defensin 1, 2, and 3 expression in oral squamous cell carcinoma. (19702947)
2009
23
Prognostic significance of molecular markers in oral squamous cell carcinoma: a multivariate analysis. (19424974)
2009
24
Expression profile of human beta-defensin 3 in oral squamous cell carcinoma. (19219676)
2009
25
LCK, survivin and PI-3K in the molecular biomarker profiling of oral lichen planus and oral squamous cell carcinoma. (20975919)
2009
26
Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma. (19048118)
2008
27
Microsatellite GTn-repeat polymorphism in the promoter of heme oxygenase-1 gene is an independent predictor of tumor recurrence in male oral squamous cell carcinoma patients. (18312299)
2008
28
Expression of carbonic anhydrase IX is associated with postoperative recurrence and poor prognosis in surgically treated oral squamous cell carcinoma. (18440050)
2008
29
Hyaluronan-mediated motility: a target in oral squamous cell carcinoma. (18425326)
2008
30
Selection and quantitative detection of target genes in oral squamous cell carcinoma]. (17074177)
2006
31
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis. (17167983)
2006
32
Expression and significance of angiopoietins in oral squamous cell carcinoma]. (15804026)
2005
33
Establishment and characterization of a cisplatin-resistant oral squamous cell carcinoma cell line, H-1R. (16211297)
2005
34
A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line. (14733907)
2004
35
Mutation and aberrant expression of Caveolin-1 in human oral squamous cell carcinomas and oral cancer cell lines. (14719121)
2004
36
Association between gene expression profile and tumor invasion in oral squamous cell carcinoma. (15381369)
2004
37
Characteristic cytokine generation patterns in cancer cells and infiltrating lymphocytes in oral squamous cell carcinomas and the influence of chemoradiation combined with immunotherapy on these patterns. (12759539)
2003
38
Expression of membrane type I-matrix metalloproteinase in oral squamous cell carcinoma. (12169394)
2002
39
Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma. (12009335)
2002
40
Mutational analysis of the candidate tumor suppressor gene ING1 in Indian oral squamous cell carcinoma. (11287275)
2001
41
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis. (11235994)
2000
42
Alterations of Rb, p16(INK4A) and cyclin D1 in the tumorigenesis of oral squamous cell carcinomas. (11098077)
2000
43
Human oral squamous cell carcinoma cell lines promote angiogenesis via expression of vascular endothelial growth factor and upregulation of KDR/flk-1 expression in endothelial cells. (10889925)
2000
44
Genetically high susceptibility to oral squamous cell carcinoma in terms of combined genotyping of CYP1A1 and GSTM1 genes. (10793329)
2000
45
Apoptosis and p53 are associated with effect of preoperative radiation in oral squamous cell carcinomas. (10799741)
2000
46
Multiparameter flow cytometry for simultaneous assessment of p53 protein expression and cellular DNA content in oral squamous cell carcinomas: evidence for the development of aneuploid clones from p53-deficient diploid progenitor cells. (11029495)
2000
47
Cell cycle proteins and the development of oral squamous cell carcinoma. (10621856)
1999
48
Prevalence of Epstein-Barr virus in oral squamous cell carcinoma. (10451485)
1999
49
p53 expression above the basal cell layer in oral mucosa is an early event of malignant transformation and has predictive value for developing oral squamous cell carcinoma. (9664901)
1998
50
EGFR and PCNA expression in oral squamous cell carcinomas--a valuable tool in estimating the patient's prognosis. (11706420)
1993

Variations for Oral Squamous Cell Carcinoma

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Expression for genes affiliated with Oral Squamous Cell Carcinoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Oral Squamous Cell Carcinoma

Search GEO for disease gene expression data for Oral Squamous Cell Carcinoma.

Pathways for genes affiliated with Oral Squamous Cell Carcinoma

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50PathCards, 38NCBI BioSystems Database, 30KEGG
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Pathways related to Oral Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1MIR17, MIR181A1
28.8HRAS, MIR125B1, MIR181A1, MIR181A2, MIR124-2, MIR17

Compounds for genes affiliated with Oral Squamous Cell Carcinoma

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GO Terms for genes affiliated with Oral Squamous Cell Carcinoma

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16Gene Ontology
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Biological processes related to Oral Squamous Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1biological_processGO:0081509.4MAGEA12, FAM215A, ORAOV1, GPR87

Products for genes affiliated with Oral Squamous Cell Carcinoma

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Sources for Oral Squamous Cell Carcinoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet