MCID: ORB011
MIFTS: 21

Orbit Rhabdomyosarcoma malady

Category: Cancer diseases

Aliases & Classifications for Orbit Rhabdomyosarcoma

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Aliases & Descriptions for Orbit Rhabdomyosarcoma:

Name: Orbit Rhabdomyosarcoma 10 12
Rhabdomyosarcoma of the Orbit 10 36 65
 
Rhabdomyosarcoma of Orbit 10

Classifications:



External Ids:

Disease Ontology10 DOID:3259
MeSH36 C537605
SNOMED-CT59 254994000
NCIt42 C4543
UMLS65 C0346347

Summaries for Orbit Rhabdomyosarcoma

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MalaCards based summary: Orbit Rhabdomyosarcoma, also known as rhabdomyosarcoma of the orbit, is related to orbit embryonal rhabdomyosarcoma and orbit alveolar rhabdomyosarcoma. An important gene associated with Orbit Rhabdomyosarcoma is MB (Myoglobin). Affiliated tissues include breast, and related mouse phenotypes are embryo and muscle.

Related Diseases for Orbit Rhabdomyosarcoma

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Graphical network of the top 20 diseases related to Orbit Rhabdomyosarcoma:



Diseases related to orbit rhabdomyosarcoma

Symptoms for Orbit Rhabdomyosarcoma

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Drugs & Therapeutics for Orbit Rhabdomyosarcoma

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Drugs for Orbit Rhabdomyosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Cyclophosphamideapproved, investigationalPhase 2264350-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
2
DactinomycinapprovedPhase 24650-76-02019, 457193
Synonyms:
(- )-actinomycin d
(-)-actinomycin d
-pentone
01815_FLUKA
1H-Pyrrolo(2,1-1)-(1,4,7,10,13)oxatetraazacyclohexadecine
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-I)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
50-76-0
A1410_SIGMA
A4262_SIGMA
A9415_SIGMA
AC1L1CQX
AC1L9W52
ACT
ACT D
ACTINOMYCIN D
ACTINOMYCIN D AMP
ACTINOMYCIN-D
ACTO-D
ACon0_000471
ACon1_001004
AD
AD (VAN)
AI3-26374
ActD
Actactinomycin A IV
Actactinomycin a Iv
Actinomycin 11 Cosmegen
Actinomycin 11 cosmegen
Actinomycin 7
Actinomycin A IV
Actinomycin Aiv
Actinomycin C (sub1)
Actinomycin C(sub1)
Actinomycin C1
Actinomycin D
Actinomycin D (JP15)
Actinomycin D deriv. of 3H-phenoxaocardazine
Actinomycin D, sodium deoxyribonucleic acid complex
Actinomycin I
Actinomycin I (sub1)
Actinomycin I(sub 1)
Actinomycin I(sub1)
Actinomycin I1
Actinomycin IV
Actinomycin Iv
Actinomycin X 1
Actinomycin X1
Actinomycin iv
Actinomycin-(threo-val-pro-sar-meval)
Actinomycin-?IV
Actinomycin-[threo-val-pro-sar-meval]
Actinomycindioic D Acid, Dilactone
Actinomycindioic D acid, dilactone
Acto-D
Antibiotic From Streptomyces Parvullus
Antibiotic from Streptomyces parvullus
BCBcMAP01_000155
BRD-A42383464-001-02-2
Bio1_000342
Bio1_000831
Bio1_001320
C06770
C1
C62H86N12O16
CBiol_002056
CCRIS 9
CHEBI:123721
CHEBI:27666
CHEMBL1554
CHEMBL427947
CID2019
 
CID457193
COSMEGEN (TN)
CPD000469227
Chounghwamycin B
Cosmegen
D Actinomycin
D00214
DACTINOMYCIN
DB00970
DVA-DPR-SAR-MVA-(c1)DTH-PXZ-(c11)DTH-DVA-DPR-SAR-MVA
Dactinomicina
Dactinomicina [INN-Spanish]
Dactinomycin
Dactinomycin (USP)
Dactinomycin D
Dactinomycin [USAN:BAN]
Dactinomycine
Dactinomycine [INN-French]
Dactinomycinum
Dactinomycinum [INN-Latin]
Dilactone Actinomycin D Acid
Dilactone Actinomycindioic D Acid
Dilactone actin omycindioic D acid
Dilactone actinomycin D acid
Dilactone actinomycindioic D acid
EINECS 200-063-6
FT-0080366
GNF-PF-1977
HBF 386
HBF 386 Meractinomycin
HBF 386 meractinomycin
HMS2052O17
HSDB 3220
LMPK14000005
LS-142
Lyovac Cosmegen
Lyovac cosmegen
MEGxm0_000350
MLS001424196
Meractinomycin
MolPort-001-739-741
MolPort-003-925-177
NCGC00025059-02
NCGC00090796-01
NCGC00161622-01
NCGC00161622-02
NCGC00169767-01
NCI-C04682
NCI60_030539
NP-005932
NSC 3053
NSC-3053
NSC191297
NSC3053
Neuro_000003
Oncostatin K
Oxamide
PXZ-THR-DVA-PRO-SAR-MVA-THR-DVA-PRO-SAR-MVA
SAM001246846
SMP1_000005
SMR000469227
UNII-1CC1JFE158
UPCMLD-DP055
UPCMLD-DP055:001
UPCMLD-DP055:002
WLN: 16- AN FVN IVN LVO PVM SVTJ G1 J1 KY1&1 N1 RY1&1
X 97
actd
actinomycin D
actinomycin cl
actinomycin x i
actinomyein-theo-val-pro-sar-meval
dactinomyein d
o)-(1-oxo-1,2-ethanediyl)]bis(N-methyl)L-valine
3
Vincristineapproved, investigationalPhase 28632068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
4Immunologic FactorsPhase 218483
5Nucleic Acid Synthesis InhibitorsPhase 23836
6Tubulin ModulatorsPhase 24279
7Immunosuppressive AgentsPhase 210422
8Antirheumatic AgentsPhase 28496
9Antibiotics, AntitubercularPhase 25971
10Anti-Bacterial AgentsPhase 29140
11Anti-Infective AgentsPhase 217220
12Antimitotic AgentsPhase 24296
13Antineoplastic Agents, PhytogenicPhase 24294
14Antineoplastic Agents, AlkylatingPhase 23406
15Alkylating AgentsPhase 23582

Interventional clinical trials:

idNameStatusNCT IDPhase
1Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal RhabdomyosarcomaRecruitingNCT00245141Phase 2

Search NIH Clinical Center for Orbit Rhabdomyosarcoma


Cochrane evidence based reviews: rhabdomyosarcoma of the orbit

Genetic Tests for Orbit Rhabdomyosarcoma

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Anatomical Context for Orbit Rhabdomyosarcoma

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MalaCards organs/tissues related to Orbit Rhabdomyosarcoma:

33
Breast

Animal Models for Orbit Rhabdomyosarcoma or affiliated genes

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MGI Mouse Phenotypes related to Orbit Rhabdomyosarcoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.6MB, MYOG, NF1
2MP:00053698.5MB, MYOG, NF1
3MP:00053888.4MB, MYOG, NF1

Publications for Orbit Rhabdomyosarcoma

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Articles related to Orbit Rhabdomyosarcoma:

(show all 18)
idTitleAuthorsYear
1
Distribution of Hepatitis C virus genotypes in city of Mashhad, North-east of Iran. (24399389)
2014
2
Dyschromatosis universalis hereditaria with involvement of palms. (25165647)
2014
3
Surgical and endovascular treatment of severe complications secondary to noncirrhotic portal hypertension: experience of 56 cases. (23465435)
2013
4
Probable IgG4-related pachymeningitis: a case with transverse sinus obliteration. (23320997)
2013
5
Ozone induces glucose intolerance and systemic metabolic effects in young and aged Brown Norway rats. (24103449)
2013
6
Grapheme-color synesthesia and posttraumatic stress disorder: preliminary results from the veterans health study. (23115347)
2012
7
Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. (21338575)
2011
8
A case of recurrent polymyalgia rheumatica-like complications with pregnancy. (19466422)
2010
9
Transcription factor YY1 expression in human gastrointestinal cancer cells. (19360355)
2009
10
A protein phosphatase 2A (PP2A) inhibition assay using a recombinant enzyme for rapid detection of microcystins. (18430448)
2008
11
Absence and myoclonic status epilepticus precipitated by antiepileptic drugs in idiopathic generalized epilepsy. (16513683)
2006
12
H. pylori infection increases levels of exhaled nitrate. (16181348)
2005
13
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. (11734846)
2001
14
Metastatic carcinomatous cirrhosis and hepatic hemosiderosis in a patient heterozygous for the H63D genotype. (11473464)
2001
15
Regional localization of the human EGF-like growth factor CRIPTO gene (TDGF-1) to chromosome 3p21. (7860072)
1995
16
Colectomy for idiopathic megarectum and megacolon. (1773963)
1991
17
The primary structure of the 32-kDa subunit of human replication protein A. (2406247)
1990
18
Functional similarities of asbestosis and cryptogenic fibrosing alveolitis. (3194877)
1988

Variations for Orbit Rhabdomyosarcoma

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Expression for genes affiliated with Orbit Rhabdomyosarcoma

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Search GEO for disease gene expression data for Orbit Rhabdomyosarcoma.

Pathways for genes affiliated with Orbit Rhabdomyosarcoma

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GO Terms for genes affiliated with Orbit Rhabdomyosarcoma

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Biological processes related to Orbit Rhabdomyosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1skeletal muscle tissue developmentGO:00075199.1MYOG, NF1

Sources for Orbit Rhabdomyosarcoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet