MCID: ORB008
MIFTS: 20

Orbital Plasma Cell Granuloma malady

Categories: Eye diseases

Aliases & Classifications for Orbital Plasma Cell Granuloma

Aliases & Descriptions for Orbital Plasma Cell Granuloma:

Name: Orbital Plasma Cell Granuloma 12 14
Orbital Pseudotumor 42 69
Orbital Myositis 12 69
Plasma Cell Granuloma, Orbital 69
Pseudotumor of Orbit 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9369
ICD10 33 H05.11
MeSH 42 D016727
SNOMED-CT 64 302901005 72789009
UMLS 69 C0085270

Summaries for Orbital Plasma Cell Granuloma

MalaCards based summary : Orbital Plasma Cell Granuloma, also known as orbital pseudotumor, is related to celiac disease and myositis. An important gene associated with Orbital Plasma Cell Granuloma is TNFRSF1B (TNF Receptor Superfamily Member 1B). The drugs rituximab and Immunoglobulin G have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Orbital Plasma Cell Granuloma

Diseases related to Orbital Plasma Cell Granuloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
id Related Disease Score Top Affiliating Genes
1 celiac disease 29.5 MRAP TNFRSF1B
2 myositis 10.5
3 occupational dermatitis 10.2 MRAP TNFRSF1B
4 hypertrophic elongation of cervix 10.2 IFNA2 TNFRSF1B
5 plasmodium falciparum malaria 10.2 MRAP TNFRSF1B
6 bladder calculus 10.2 MRAP TNFRSF1B
7 nephronophthisis 1, juvenile 10.1 MRAP TNFRSF1B
8 cryptococcosis 10.1 MRAP TNFRSF1B
9 conjunctival vascular disease 10.1 MRAP TNFRSF1B
10 vibratory urticaria 10.1 IFNA2 MRAP
11 inclusion conjunctivitis 10.1 MRAP TNFRSF1B
12 patau syndrome 10.1 MRAP TNFRSF1B
13 multiple carboxylase deficiency 10.1 CTLA4 TNFRSF1B
14 cardioauditory syndrome of sanchez cascos 10.1 IFNA2 SST
15 uterine ligament clear cell adenocarcinoma 10.1 MRAP TNFRSF1B
16 eating disorder 10.1 IFNA2 TNFRSF1B
17 sarcomatoid squamous cell skin carcinoma 10.1 SMUG1 TNFRSF1B
18 hepatitis b reinfection following liver transplantation 10.0 IFNA2 SST
19 bone angioendothelial sarcoma 10.0 MRAP TNFRSF1B
20 sporadic breast cancer 10.0 SMUG1 TNFRSF1B
21 coarctation of aorta 10.0 CTLA4 IFNA2 TNFRSF1B
22 mammary paget's disease 10.0 SMUG1 TNFRSF1B
23 esophageal candidiasis 10.0 CTLA4 IFNA2
24 crohn's disease 10.0
25 herpes zoster 10.0
26 glomangiomyoma 10.0 CTLA4 SST
27 myxedema 10.0 IFNA2 SMUG1
28 lymph node adenoid cystic carcinoma 10.0 SMUG1 TNFRSF1B
29 fallopian tube adenomatoid tumor 10.0 MRAP SMUG1
30 intracranial hemorrhage in brain cerebrovascular malformations 10.0 MRAP TNFRSF1B
31 herpes zoster ophthalmicus 10.0
32 breast lymphoma 9.9 SMUG1 SST
33 oculocutaneous albinism 9.9 SMUG1 SST
34 female breast upper-inner quadrant cancer 9.9 MRAP SMUG1
35 early-onset parkinson disease 9.9 SMUG1 SST
36 myocarditis 9.9
37 giant cell myocarditis 9.9
38 vaginal yolk sac tumor 9.9 CTLA4 IFNA2 SMUG1
39 retroperitoneal leiomyosarcoma 9.9 CTLA4 IFNA2 SMUG1
40 newcastle disease 9.8 MRAP SMUG1 TNFRSF1B
41 goodpasture syndrome 9.8 CTLA4 IFNA2 MRAP TNFRSF1B
42 orbital cellulitis 9.8
43 scleritis 9.8
44 cellulitis 9.8
45 lupus erythematosus 9.8
46 colitis 9.7
47 lyme disease 9.7
48 posterior scleritis 9.7
49 pharyngitis 9.7
50 dacryoadenitis 9.7

Graphical network of the top 20 diseases related to Orbital Plasma Cell Granuloma:



Diseases related to Orbital Plasma Cell Granuloma

Symptoms & Phenotypes for Orbital Plasma Cell Granuloma

Drugs & Therapeutics for Orbital Plasma Cell Granuloma

Drugs for Orbital Plasma Cell Granuloma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved Phase 1, Phase 2 174722-31-7 10201696
2 Immunoglobulin G Phase 1, Phase 2
3 Immunoglobulins Phase 1, Phase 2
4 Antibodies Phase 1, Phase 2
5 Antirheumatic Agents Phase 1, Phase 2
6
Menthol Approved 2216-51-5 16666

Interventional clinical trials:


id Name Status NCT ID Phase
1 Rituximab in IgG4-related Disease: A Phase 1-2 Trial Completed NCT01584388 Phase 1, Phase 2
2 MRI and Orbital Tumours (MEDORT) Recruiting NCT02401906
3 Survey of Patients With Idiopathic Orbital Inflammation Syndrome Active, not recruiting NCT01443000
4 MRI Perfusion Curves Typology and Orbital Tumors (PERFORM) Enrolling by invitation NCT02434120
5 Ultrasound Exam With Doppler for the Etiological Diagnosis of Orbital Masses (PUCE) Enrolling by invitation NCT02678091

Search NIH Clinical Center for Orbital Plasma Cell Granuloma

Cochrane evidence based reviews: orbital pseudotumor

Genetic Tests for Orbital Plasma Cell Granuloma

Anatomical Context for Orbital Plasma Cell Granuloma

MalaCards organs/tissues related to Orbital Plasma Cell Granuloma:

39
Eye

Publications for Orbital Plasma Cell Granuloma

Variations for Orbital Plasma Cell Granuloma

Expression for Orbital Plasma Cell Granuloma

Search GEO for disease gene expression data for Orbital Plasma Cell Granuloma.

Pathways for Orbital Plasma Cell Granuloma

GO Terms for Orbital Plasma Cell Granuloma

Biological processes related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 8.8 IFNA2 SST TNFRSF1B

Sources for Orbital Plasma Cell Granuloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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