MCID: ORB008
MIFTS: 28

Orbital Plasma Cell Granuloma

Categories: Eye diseases

Aliases & Classifications for Orbital Plasma Cell Granuloma

MalaCards integrated aliases for Orbital Plasma Cell Granuloma:

Name: Orbital Plasma Cell Granuloma 12 14
Orbital Pseudotumor 41 69
Orbital Myositis 12 69
Plasma Cell Granuloma, Orbital 69
Pseudotumor of Orbit 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9369
ICD10 32 H05.11
MeSH 41 D016727
SNOMED-CT 64 302901005 72789009

Summaries for Orbital Plasma Cell Granuloma

MalaCards based summary : Orbital Plasma Cell Granuloma, also known as orbital pseudotumor, is related to herpes zoster and myositis. An important gene associated with Orbital Plasma Cell Granuloma is TNFRSF1B (TNF Receptor Superfamily Member 1B), and among its related pathways/superpathways are Tuberculosis and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include eye.

Related Diseases for Orbital Plasma Cell Granuloma

Diseases related to Orbital Plasma Cell Granuloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Related Disease Score Top Affiliating Genes
1 herpes zoster 30.4 FCGR3A IFNA2
2 myositis 10.6
3 transient neonatal neutropenia 10.4 FCGR3A FCGR3B
4 granulomatous hepatitis 10.4 IFNA2 TNFRSF1B
5 scleral disease 10.4 MRAP TNFRSF1B
6 iritis 10.4 MRAP TNFRSF1B
7 pustulosis of palm and sole 10.4 MRAP TNFRSF1B
8 spastic paraplegia 32, autosomal recessive 10.3 FCGR3A FCGR3B
9 tenosynovitis 10.3 MRAP TNFRSF1B
10 myxedema 10.3 CTLA4 TSHR
11 rheumatic myocarditis 10.3 FCGR3A FCGR3B
12 poliomyelitis 10.3 FCGR3A FCGR3B
13 penile disease 10.3 IFNA2 MRAP
14 acute salpingitis 10.3 MRAP TNFRSF1B
15 pericoronitis 10.3 NCAM1 TNFRSF1B
16 rhinoscleroma 10.3 NCAM1 TNFRSF1B
17 exanthema subitum 10.3 FCGR3A FCGR3B
18 panuveitis 10.3 MRAP TNFRSF1B
19 pleuropneumonia 10.3 FCGR3A FCGR3B
20 autoimmune disease of endocrine system 10.2 CTLA4 TSHR
21 cryptococcosis 10.2 FCGR3A FCGR3B
22 peroneal neuropathy 10.2 MME TNFRSF1B
23 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2 CTLA4 TSHR
24 palindromic rheumatism 10.2 MRAP TNFRSF1B
25 mycosis fungoides 10.2 CTLA4 IFNA2 TNFRSF1B
26 hypopyon 10.2 MRAP NCAM1
27 ovarian cystic teratoma 10.2 FCGR3A FCGR3B IFNA2
28 hypersensitivity reaction type iv disease 10.2 MRAP TNFRSF1B
29 neutropenia 10.1 FCGR3A FCGR3B IFNA2
30 granulomatous myositis 10.1 NCAM1 PIK3C2A TNFRSF1B
31 crohn's disease 10.1
32 herpes zoster ophthalmicus 10.1
33 myocarditis 10.1
34 lung combined type small cell carcinoma 10.1 MME NCAM1
35 histrionic personality disorder 10.1 KNTC1 MME
36 extrahepatic bile duct adenocarcinoma 10.1 MME NCAM1
37 diffuse infiltrative lymphocytosis syndrome 10.0 FCGR3A FCGR3B MRAP
38 giant cell myocarditis 10.0
39 dependent personality disorder 10.0 KNTC1 MME
40 malignant skin fibrous histiocytoma 10.0 CTLA4 IFNA2 NCAM1
41 chronic nk-cell lymphocytosis 10.0 FCGR3A FCGR3B NCAM1
42 malignant dermis tumor 10.0 CTLA4 IFNA2 NCAM1
43 carcinoid syndrome 10.0 IFNA2 SST
44 spermatocele 10.0 MME NCAM1
45 anterior scleritis 10.0 MRAP NCAM1 TNFRSF1B
46 rete testis neoplasm 10.0 MME NCAM1
47 cystadenofibroma 10.0 MME NCAM1
48 nephrogenic adenofibroma 9.9 MME NCAM1
49 episodic pain syndrome, familial, 1 9.9
50 orbital cellulitis 9.9

Graphical network of the top 20 diseases related to Orbital Plasma Cell Granuloma:



Diseases related to Orbital Plasma Cell Granuloma

Symptoms & Phenotypes for Orbital Plasma Cell Granuloma

Drugs & Therapeutics for Orbital Plasma Cell Granuloma

Search Clinical Trials , NIH Clinical Center for Orbital Plasma Cell Granuloma

Cochrane evidence based reviews: orbital pseudotumor

Genetic Tests for Orbital Plasma Cell Granuloma

Anatomical Context for Orbital Plasma Cell Granuloma

MalaCards organs/tissues related to Orbital Plasma Cell Granuloma:

38
Eye

Publications for Orbital Plasma Cell Granuloma

Articles related to Orbital Plasma Cell Granuloma:

(show all 18)
# Title Authors Year
1
IgG4-Related Disease With Orbital Pseudotumors Treated With Rituximab Combined With Palpebral Surgery. ( 28055067 )
2017
2
Myeloid sarcoma: a rare case of an orbital mass mimicking orbital pseudotumor requiring neurosurgical intervention. ( 25478260 )
2014
3
A case report of hemicrania continua-like headache due to ipsilateral inflammatory orbital pseudotumor. ( 25168202 )
2014
4
Case of recurrent exophthalmos: angioedema versus idiopathic orbital pseudotumor. ( 24565625 )
2013
5
Unilateral optic neuritis, scleritis and exudative retinal detachment due to recurrent orbital pseudotumor. ( 23961032 )
2012
6
Orbital pseudotumor in a child with juvenile rheumatoid arthritis. ( 15977874 )
2005
7
Orbital pseudotumor as an initial manifestation of multicentric Castleman's disease. ( 16365797 )
2005
8
Systemic malignant lymphoma 17 years after bilateral orbital pseudotumor. ( 15486778 )
2004
9
Central retinal vascular occlusion by orbital pseudotumor. ( 15187672 )
2004
10
A case of orbital pseudotumor masquerading as orbital cellulitis in a patient with proptosis and fever. ( 9368248 )
1997
11
Cystoid macular edema as an initial symptom of inflammatory orbital pseudotumor. ( 9216015 )
1997
12
Orbital pseudotumor as a presenting sign of temporal arteritis. ( 7554567 )
1995
13
Primary anetoderma and orbital pseudotumor. ( 7896484 )
1995
14
Herpes zoster ophthalmicus with orbital pseudotumor syndrome complicated by optic nerve infarction and cerebral granulomatous angiitis: MR-pathologic correlation. ( 8427086 )
1993
15
Intracranial extension of an orbital pseudotumor accompanied by internal carotid artery occlusion--case report. ( 1280778 )
1992
16
Role of testing for anticytoplasmic autoantibodies in the differential diagnosis of scleritis and orbital pseudotumor. ( 2388488 )
1990
17
Adult-onset Still's disease and inflammatory orbital pseudotumor. ( 3857478 )
1985
18
Orbital leiomyoma accompanied by orbital pseudotumor. ( 7131926 )
1982

Variations for Orbital Plasma Cell Granuloma

Expression for Orbital Plasma Cell Granuloma

Search GEO for disease gene expression data for Orbital Plasma Cell Granuloma.

Pathways for Orbital Plasma Cell Granuloma

Pathways related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.69 FCGR3A FCGR3B IFNA2
2 11.4 IFNA2 MME NCAM1
3 11 IFNA2 MME NCAM1
4 10.62 CTLA4 FCGR3A FCGR3B

GO Terms for Orbital Plasma Cell Granuloma

Cellular components related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.32 CTLA4 FCGR3A FCGR3B KNTC1 MME MRAP
2 external side of plasma membrane GO:0009897 9.13 CTLA4 FCGR3A NCAM1

Biological processes related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.26 CTLA4 FCGR3A FCGR3B TNFRSF1B
2 positive regulation of cAMP biosynthetic process GO:0030819 9.16 MRAP TSHR
3 cell surface receptor signaling pathway GO:0007166 8.92 IFNA2 SST TNFRSF1B TSHR

Molecular functions related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 IgG binding GO:0019864 8.62 FCGR3A FCGR3B

Sources for Orbital Plasma Cell Granuloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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