MCID: OSS002
MIFTS: 41

Ossifying Fibromyxoid Tumor malady

Cancer diseases category

Summaries for Ossifying Fibromyxoid Tumor

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MalaCards based summary: Ossifying Fibromyxoid Tumor, also known as ossifying fibromyxoma, is related to sarcoma and endometrial stromal sarcoma. An important gene associated with Ossifying Fibromyxoid Tumor is S100B (S100 calcium binding protein B), and among its related pathways is Striated Muscle Contraction. The compounds fk 888 and edss have been mentioned in the context of this disorder. Affiliated tissues include bone, thyroid and breast, and related mouse phenotype behavior/neurological.

Aliases & Classifications for Ossifying Fibromyxoid Tumor

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Ossifying Fibromyxoid Tumor, Aliases & Descriptions:

Name: Ossifying Fibromyxoid Tumor 10 12 62
 
Ossifying Fibromyxoma 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology10 DOID:2685
NCIt40 C6582

Related Diseases for Ossifying Fibromyxoid Tumor

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Diseases related to Ossifying Fibromyxoid Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 80)
idRelated DiseaseScoreTop Affiliating Genes
1sarcoma30.6S100A1, S100B, ACTC1, DES, B3GAT1
2endometrial stromal sarcoma30.5ACTC1, DES, MME
3nasopharyngitis10.3
4extraosseous osteosarcoma10.3
5mediastinitis10.3
6thyroiditis10.3
7fibrous meningioma10.1S100B
8pineocytoma10.1S100B
9rosai-dorfman disease10.1S100B
10histiocytosis10.1S100B
11fasciitis10.1ACTC1
12ganglioglioma10.1S100B
13metanephric adenoma10.0B3GAT1
14infantile myofibromatosis10.0DES
15secondary progressive multiple sclerosis10.0MBP
16syringoma10.0S100A1, S100B
17langerhans-cell histiocytosis10.0S100B, S100A1
18papilloma10.0ACTC1
19malignant peripheral nerve sheath tumor10.0S100A1, S100B
20paraganglioma10.0S100B, S100A1
21mucoepidermoid carcinoma10.0ACTC1, S100A1
22epithelioid leiomyosarcoma10.0DES, ACTC1
23pseudosarcomatous fibromatosis10.0ACTC1, DES
24sex cord-gonadal stromal tumor10.0S100B, DES
25lipoma10.0DES, S100A1
26spindle cell carcinoma10.0ACTC1, DES
27desmoid disease, hereditary10.0ACTC1, DES
28rhabdoid tumor10.0DES, ACTC1
29microphthalmia10.0S100B, ACTC1
30embryonal rhabdomyosarcoma10.0DES, ACTC1
31sarcoma, synovial10.0DES, S100B
32myoepithelioma10.0ACTC1, S100A1, S100B
33uterine fibroid10.0DES, S100A1
34salivary gland adenoid cystic carcinoma10.0ACTC1, S100B, S100A1
35oxyphilic adenoma10.0MME, S100A1
36mesothelioma, somatic10.0S100A1, DES
37tubular adenocarcinoma10.0ACTC1, MME
38renal clear cell carcinoma10.0MME, S100A1
39granular cell tumor10.0S100B, DES, S100A1
40pulmonary fibrosis, idiopathic10.0S100A1, ACTC1
41chordoma10.0DES, S100A1, S100B
42uterine sarcoma10.0DES, MME
43glomus tumor10.0S100A1, ACTC1, DES
44peripheral primitive neuroectodermal tumor10.0S100B, DES, S100A1
45chondrosarcoma10.0S100B, S100A1, DES
46angiomyolipoma10.0DES, ACTC1, S100A1
47fibroma10.0DES, ACTC1, S100A1
48fibromatosis10.0DES, ACTC1, S100A1
49spindle cell sarcoma10.0S100B, ACTC1, DES
50abrikosov's tumor10.0S100A1, ACTC1, DES

Graphical network of the top 20 diseases related to Ossifying Fibromyxoid Tumor:



Diseases related to ossifying fibromyxoid tumor

Symptoms for Ossifying Fibromyxoid Tumor

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Drugs & Therapeutics for Ossifying Fibromyxoid Tumor

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Drug clinical trials:

Search ClinicalTrials for Ossifying Fibromyxoid Tumor

Search NIH Clinical Center for Ossifying Fibromyxoid Tumor

Genetic Tests for Ossifying Fibromyxoid Tumor

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Anatomical Context for Ossifying Fibromyxoid Tumor

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MalaCards organs/tissues related to Ossifying Fibromyxoid Tumor:

33
Bone, Thyroid, Breast, Skin, Testes, Tongue

Animal Models for Ossifying Fibromyxoid Tumor or affiliated genes

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MGI Mouse Phenotypes related to Ossifying Fibromyxoid Tumor:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.3MBP, B3GAT1, S100B, S100A1, DES

Publications for Ossifying Fibromyxoid Tumor

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Articles related to Ossifying Fibromyxoid Tumor:

(show top 50)    (show all 75)
idTitleAuthorsYear
1
Ossifying fibromyxoid tumor (OFMT) - A rare cause of a painful thumb. (25603305)
2015
2
Pediatric low-grade fibromyxoid sarcoma mimicking ossifying fibromyxoid tumor: adding to the diagnostic spectrum of soft tissue tumors with a bony shell. (25532939)
2015
3
Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors-molecular characterization shows genetic overlap with endometrial stromal sarcoma. (24285434)
2014
4
Ossifying fibromyxoid tumor metastatic to the thyroid: a case report and review of the literature. (24932821)
2014
5
Atypical ossifying fibromyxoid tumor. (25105387)
2014
6
PHF1 rearrangements in ossifying fibromyxoid tumors of soft parts: A fluorescence in situ hybridization study of 41 cases with emphasis on the malignant variant. (23887158)
2013
7
Extraosseous osteosarcoma arising in recurrent ossifying fibromyxoid tumor of soft tissue: a case report. (23805469)
2013
8
Ossifying fibromyxoid tumor presenting EP400-PHF1 fusion gene. (23806526)
2013
9
Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report. (23599783)
2013
10
Malignant ossifying fibromyxoid tumor of the parapharyngeal space. (23076857)
2012
11
Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors. (22796436)
2012
12
Cytological features of ossifying fibromyxoid tumor of soft parts. (23112466)
2012
13
Ossifying fibromyxoid tumor - Diagnostic challenge for a cytopathologist. (22919424)
2012
14
Osteopontin in ossifying fibromyxoid tumor. (21505404)
2011
15
Paraspinal malignant ossifying fibromyxoid tumor with spinal involvement. (20801659)
2010
16
Ossifying fibromyxoid tumor of soft parts mimicking a schwannoma with uncommon histology: a potential diagnostic pitfall. (19125736)
2009
17
Ossifying fibromyxoid tumor in the mandibular gingiva: case report and review of the literature. (19335090)
2009
18
Ossifying fibromyxoid tumor of soft parts--a clinicopathologic and immunohistochemical study of 104 cases with long-term follow-up and a critical review of the literature. (18469710)
2008
19
Ossifying fibromyxoid tumor of soft parts. Report of a rare tumor in Kuwait. (18523405)
2008
20
Sonographic features of an ossifying fibromyxoid tumor of the buttock. (18424660)
2008
21
Resection of metastatic pulmonary lesion of ossifying fibromyxoid tumor extending into the left atrium and ventricle via pulmonary vein. (16762602)
2007
22
Test and teach. An unusual supraclavicular lump. Ossifying fibromyxoid tumor. (17558865)
2007
23
Ossifying fibromyxoid tumor of soft parts with clonal chromosomal aberrations. (17656260)
2007
24
Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor. (16731174)
2006
25
Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst. (16919031)
2006
26
Subcutaneous ossifying fibromyxoid tumor. (17083695)
2006
27
Ossifying fibromyxoid tumor of the orbit. (16550049)
2006
28
Ossifying fibromyxoid tumor of the nasal septum. (16600550)
2006
29
Ossifying fibromyxoid tumor of the skin: a report of 2 cases with light microscopic, immunohistochemical, and electron microscopic characterization. (15793515)
2005
30
Cytologic diagnosis of ossifying fibromyxoid tumor of soft tissue: a case report. (14696144)
2004
31
Ossifying fibromyxoid tumor of the ethmoid sinus in a newborn: report of a case and literature review. (14725991)
2004
32
Ossifying fibromyxoid tumor of soft parts: a clinicopathologic study of 70 cases with emphasis on atypical and malignant variants. (12657926)
2003
33
Ossifying fibromyxoid tumor of soft parts. Cytogenetic findings. (11943338)
2002
34
Fine needle aspiration cytology of the malignant variant of ossifying fibromyxoid tumor of soft parts: a case report. (11575654)
2001
35
Ossifying fibromyxoid tumor of soft parts: a clinicopathological analysis of eight cases]. (11866971)
2001
36
Ossifying fibromyxoid tumor of soft parts: clinicopathologic, immunohistochemical and ultrastructural study of four cases. (10504543)
1999
37
Ossifying fibromyxoid tumor of soft parts in a child: a case report. (10466619)
1999
38
Ossifying fibromyxoid tumor resembling parosteal osteosarcoma. (9840396)
1998
39
Ossifying fibromyxoid tumor of soft parts: a report of 17 cases with emphasis on unusual histological features. (9869828)
1997
40
Radiographic appearance of an ossifying fibromyxoid tumor of soft parts. (9361359)
1997
41
Ossifying fibromyxoid tumor misdiagnosed as follicular neoplasia. A case report. (9990254)
1997
42
Ossifying fibromyxoid tumor of the retroperitoneum. (10846554)
1996
43
Ossifying fibromyxoid tumor of soft parts. (8864929)
1996
44
Nasopharyngeal nonossifying variant of ossifying fibromyxoid tumor: CT and MR findings. (7639139)
1995
45
New observations on three cases of ossifying fibromyxoid tumor of soft parts. (7953442)
1994
46
Ossifying subcutaneous tumor with myofibroblastic differentiation: a variant of ossifying fibromyxoid tumor of soft parts? (7804436)
1994
47
Ossifying fibromyxoid tumor of soft parts: a case report. (8459644)
1993
48
Case report 685: Ossifying fibromyxoid tumor of the soft parts of the upper arm. (1776029)
1991
49
Ossifying fibromyxoid tumor. Something new to mull over. (1899529)
1991
50
Ossifying fibromyxoid tumor. (2123607)
1990

Variations for Ossifying Fibromyxoid Tumor

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Expression for genes affiliated with Ossifying Fibromyxoid Tumor

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Search GEO for disease gene expression data for Ossifying Fibromyxoid Tumor.

Pathways for genes affiliated with Ossifying Fibromyxoid Tumor

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Pathways related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7ACTC1, DES

Compounds for genes affiliated with Ossifying Fibromyxoid Tumor

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Compounds related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1fk 8884510.0B3GAT1, MME
2edss4510.0S100B, MBP
3c3bot (154-182)6110.0S100B, MBP
4ono 25066110.0MBP, S100B
5nogo-66 (1-40)6110.0S100B, MBP
6mog (35-55)6110.0S100B, MBP
7plp (139-151)6110.0S100B, MBP
8olopatadine45 1310.9S100B, S100A1
92-methoxyethanol459.9S100A1, ACTC1
102,3-cyclic nucleotide459.9MBP, S100B
11orcein459.8S100B, DES, ACTC1
12s 100459.8ACTC1, DES, S100B
13reticulin459.8S100B, ACTC1, DES
14thiorphan45 30 1311.8MME, B3GAT1
15toluidine459.8S100A1, DES
16imatinib45 51 1311.7DES, ACTC1, S100B
17bromodeoxyuridine459.6MME, DES, S100B
18biotin45 26 1311.5DES, ACTC1, S100A1
19acth459.5S100B, B3GAT1, MME
20silver459.4MBP, S100A1, DES
21mucicarmine459.3ACTC1, S100B, S100A1, DES
22b 723459.3ACTC1, DES, S100B, S100A1
23hematoxylin459.3S100A1, DES, ACTC1, S100B
24actomyosin459.3ACTC1, S100A1
25formaldehyde45 2610.3DES, S100B, MBP, ACTC1
26methionine459.3S100B, MME, DES
27glycogen45 2610.3DES, S100B, S100A1, ACTC1
28iron45 2610.2DES, ACTC1, S100A1, S100B
29norepinephrine45 26 1311.2MBP, DES, S100B
30cyclosporin a45 30 6111.2MME, ACTC1, S100B, MBP
31heparin45 30 26 1312.2MBP, S100B, DES, B3GAT1
3212-o-tetradecanoylphorbol 13-acetate459.2DES, MME, MBP
33steroid459.1MME, DES, ACTC1, S100B
34lactate459.1DES, MBP, S100B, MME
35thymidine45 2610.1DES, MBP, MME, S100B
36adenylate459.1DES, MME, S100B, MBP
37vegf459.1S100B, DES, ACTC1, MME
38testosterone45 61 26 1312.0S100B, MME, DES, B3GAT1, ACTC1
39creatinine458.8S100B, DES, MME, ACTC1, MBP
40oxygen45 269.8DES, MME, S100B, ACTC1
41arginine458.8B3GAT1, S100B, MME, DES, MBP
42nitric oxide45 26 1310.8DES, MME, S100B, B3GAT1, S100A1
43acetylcholine45 51 30 26 1312.7S100A1, S100B, MBP, MME, DES
44cysteine458.6DES, MBP, S100B, S100A1, MME
45progesterone45 30 61 26 1312.5ACTC1, DES, MME, S100A1, S100B, B3GAT1
46calcium45 51 26 1311.4S100A1, B3GAT1, MME, DES, S100B, ACTC1
47paraffin458.3S100B, ACTC1, MBP, MME, DES, S100A1
48retinoic acid45 269.3MME, S100A1, ACTC1, S100B, MBP, DES
49tyrosine458.3ACTC1, DES, MBP, MME, S100B, S100A1
50estrogen458.0DES, MME, ACTC1, S100B, MBP, B3GAT1

GO Terms for genes affiliated with Ossifying Fibromyxoid Tumor

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Biological processes related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of heart contractionGO:00080169.4S100A1, DES
2substantia nigra developmentGO:00217629.4MBP, S100A1
3muscle filament slidingGO:00300499.4ACTC1, DES

Molecular functions related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:00445489.5S100B, S100A1
2calcium-dependent protein bindingGO:00483069.3S100B, S100A1
3identical protein bindingGO:00428029.2S100B, S100A1, DES

Products for genes affiliated with Ossifying Fibromyxoid Tumor

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Sources for Ossifying Fibromyxoid Tumor

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4CDC
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24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet