MCID: OSS002
MIFTS: 39

Ossifying Fibromyxoid Tumor malady

Cancer diseases category

Summaries for Ossifying Fibromyxoid Tumor

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32MalaCards
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MalaCards: Ossifying Fibromyxoid Tumor, also known as ossifying fibromyxoma, is related to endometrial stromal sarcoma and sarcoma. An important gene associated with Ossifying Fibromyxoid Tumor is S100B (S100 calcium binding protein B), and among its related pathways is Striated Muscle Contraction. The compounds glycogen and fk 888 have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and testes.

Aliases & Classifications for Ossifying Fibromyxoid Tumor

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

ossifying fibromyxoid tumor 8 10 60
ossifying fibromyxoma 8


External Ids:

Disease Ontology8 DOID:2685
NCIt39 C6582

Related Diseases for Ossifying Fibromyxoid Tumor

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17GeneCards, 18GeneDecks
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Diseases related to Ossifying Fibromyxoid Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 107)
idRelated DiseaseScoreTop Affiliating Genes
1endometrial stromal sarcoma30.3VIM, DES, ACTC1, MME
2sarcoma30.3DES, ACTC1, B3GAT1, VIM, S100B, CREB3L2
3osteosarcoma10.4
4nonossifying fibromyxoid tumor10.2
5nasopharyngitis10.2
6endometrial stromal tumor10.2
7extraosseous osteosarcoma10.2
8mediastinitis10.2
9hemangioblastoma10.0S100B
10histiocytosis10.0S100B
11fasciitis10.0ACTC1
12lymphangioleiomyomatosis10.0DES
13metanephric adenoma10.0B3GAT1
14teratoma10.0ACTC1
15renal oncocytoma10.0S100A1
16infantile myofibromatosis10.0DES
17fibrous meningioma10.0S100B
18neurilemmoma10.0B3GAT1
19pilocytic astrocytoma10.0S100B
20papilloma10.0ACTC1
21germ cell cancer10.0B3GAT1
22pineocytoma10.0S100B
23rosai-dorfman disease10.0S100B
24cystadenoma10.0MME
25glomerulonephritis10.0MME
26endometrial carcinoma10.0MME
27oxyphilic adenoma10.0S100A1
28extraskeletal myxoid chondrosarcoma10.0CREB3L2
29hemangioma10.0ACTC1
30paraganglioma10.0S100B, S100A1
31syringoma10.0S100A1, S100B
32ischemia10.0MME
33pneumonia10.0MME
34ganglioneuroblastoma10.0S100B
35endometriosis10.0ACTC1
36langerhans-cell histiocytosis10.0S100B, S100A1
37lipoma10.0DES, S100A1
38adenomatoid tumor10.0VIM
39congestive heart failure10.0MME
40desmoid tumor10.0ACTC1, DES
41perineurioma10.0VIM, S100B
42angiosarcoma10.0VIM, ACTC1
43embryonal rhabdomyosarcoma10.0DES, ACTC1
44liposarcoma10.0VIM, DES
45myopathy10.0DES
46mesenchymal chondrosarcoma10.0DES, VIM
47tubular adenocarcinoma10.0ACTC1, MME
48adenoma10.0ACTC1, B3GAT1, S100A1
49alveolar soft part sarcoma10.0VIM, DES
50malignant mixed mullerian tumor10.0MME, VIM

Graphical network of the top 20 diseases related to Ossifying Fibromyxoid Tumor:



Diseases related to ossifying fibromyxoid tumor

Clinical Features for Ossifying Fibromyxoid Tumor

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Drugs & Therapeutics for Ossifying Fibromyxoid Tumor

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ossifying Fibromyxoid Tumor

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Anatomical Context for Ossifying Fibromyxoid Tumor

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32MalaCards
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MalaCards organs/tissues related to Ossifying Fibromyxoid Tumor:

32
Bone, Skin, Testes, Tongue

Animal Models for Ossifying Fibromyxoid Tumor or affiliated genes

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Publications for Ossifying Fibromyxoid Tumor

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50PubMed
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Articles related to Ossifying Fibromyxoid Tumor:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors-molecular characterization shows genetic overlap with endometrial stromal sarcoma. (24285434)
2014
2
Ossifying fibromyxoid tumor presenting EP400-PHF1 fusion gene. (23806526)
2013
3
Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report. (23599783)
2013
4
Malignant ossifying fibromyxoid tumor of the tongue: case report and review of the literature. (23800162)
2013
5
Malignant ossifying fibromyxoid tumor of the parapharyngeal space. (23076857)
2012
6
Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors. (22796436)
2012
7
Cytological features of ossifying fibromyxoid tumor of soft parts. (23112466)
2012
8
Osteopontin in ossifying fibromyxoid tumor. (21505404)
2011
9
Ossifying fibromyxoid tumor of head and neck region: case report and systematic review of literature. (20950910)
2011
10
Ossifying fibromyxoid tumor of soft parts: a clinicopathologic, proteomic, and genomic study. (21997683)
2011
11
Paraspinal malignant ossifying fibromyxoid tumor with spinal involvement. (20801659)
2010
12
Ossifying fibromyxoid tumor of soft parts mimicking a schwannoma with uncommon histology: a potential diagnostic pitfall. (19125736)
2009
13
Ossifying fibromyxoid tumor in the mandibular gingiva: case report and review of the literature. (19335090)
2009
14
Ossifying fibromyxoid tumor with atypical histological features: a case report. (20387713)
2009
15
Ossifying fibromyxoid tumor of soft parts--a clinicopathologic and immunohistochemical study of 104 cases with long-term follow-up and a critical review of the literature. (18469710)
2008
16
Sonographic features of an ossifying fibromyxoid tumor of the buttock. (18424660)
2008
17
Ossifying fibromyxoid tumor of oral cavity. (18460251)
2008
18
Ossifying fibromyxoid tumor invading the spine: a case report and review of the literature. (18685845)
2008
19
Resection of metastatic pulmonary lesion of ossifying fibromyxoid tumor extending into the left atrium and ventricle via pulmonary vein. (16762602)
2007
20
Test and teach. An unusual supraclavicular lump. Ossifying fibromyxoid tumor. (17558865)
2007
21
Ossifying fibromyxoid tumor: invariable ultrastructural features and diverse immunophenotypic expression. (17614002)
2007
22
Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor. (16731174)
2006
23
Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst. (16919031)
2006
24
Ossifying fibromyxoid tumor of the orbit. (16550049)
2006
25
Ossifying fibromyxoid tumor of the nasal septum. (16600550)
2006
26
An unusual presentation of ossifying fibromyxoid tumor of the mandible: a case report. (17315811)
2006
27
Ossifying fibromyxoid tumor of the skin: a report of 2 cases with light microscopic, immunohistochemical, and electron microscopic characterization. (15793515)
2005
28
Ossifying fibromyxoid tumor: modified myoepithelial cell tumor? Report of three cases with immunohistochemical and electron microscopic studies. (16316954)
2005
29
Cytologic diagnosis of ossifying fibromyxoid tumor of soft tissue: a case report. (14696144)
2004
30
Ossifying fibromyxoid tumor of the ethmoid sinus in a newborn: report of a case and literature review. (14725991)
2004
31
Fine needle aspiration cytology of the malignant variant of ossifying fibromyxoid tumor of soft parts: a case report. (11575654)
2001
32
Ossifying fibromyxoid tumor of soft parts: a clinicopathological analysis of eight cases]. (11866971)
2001
33
Ossifying fibromyxoid tumor of soft parts: report of a case with novel cytogenetic findings. (11408057)
2001
34
Bone scan in ossifying fibromyxoid tumor of soft parts. (9554211)
1998
35
Ossifying fibromyxoid tumor of soft parts: a report of 17 cases with emphasis on unusual histological features. (9869828)
1997
36
Ossifying fibromyxoid tumor misdiagnosed as follicular neoplasia. A case report. (9990254)
1997
37
Ossifying fibromyxoid tumor of the retroperitoneum. (10846554)
1996
38
Ossifying fibromyxoid tumor of soft parts of the back. (8864930)
1996
39
Nasopharyngeal nonossifying variant of ossifying fibromyxoid tumor: CT and MR findings. (7639139)
1995
40
Pathologic quiz case 2. Ossifying fibromyxoid tumor. (7576484)
1995
41
Atypical and malignant variants of ossifying fibromyxoid tumor. Clinicopathologic analysis of six cases. (7661277)
1995
42
New observations on three cases of ossifying fibromyxoid tumor of soft parts. (7953442)
1994
43
Ossifying subcutaneous tumor with myofibroblastic differentiation: a variant of ossifying fibromyxoid tumor of soft parts? (7804436)
1994
44
Self assessment--1993. Non-ossifying variant of ossifying fibromyxoid tumor of soft parts. (7699128)
1994
45
Ossifying fibromyxoid tumor of soft parts: a morphological and immunohistochemical study. (8055111)
1994
46
Ossifying fibromyxoid tumor of soft parts: evidence supporting Schwann cell origin. (1740307)
1992
47
Case report 685: Ossifying fibromyxoid tumor of the soft parts of the upper arm. (1776029)
1991
48
Ossifying fibromyxoid tumor of soft parts. (1950563)
1991
49
Ossifying fibromyxoid tumor. (2123607)
1990
50
Ossifying fibromyxoid tumor of soft parts. A clinicopathological analysis of 59 cases. (2476942)
1989

Genetic Variations for Ossifying Fibromyxoid Tumor

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Expression for genes affiliated with Ossifying Fibromyxoid Tumor

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ossifying Fibromyxoid Tumor

Search GEO for disease gene expression data for Ossifying Fibromyxoid Tumor.

Pathways for genes affiliated with Ossifying Fibromyxoid Tumor

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37NCBI BioSystems Database, 53Reactome
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Pathways related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.5ACTC1, DES, VIM

Compounds for genes affiliated with Ossifying Fibromyxoid Tumor

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44Novoseek, 24HMDB, 59Tocris Bioscience, 11DrugBank, 49PharmGKB, 28IUPHAR
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Compounds related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idCompoundScoreTop Affiliating Genes
1glycogen44 2411.6ACTC1
2fk 8884410.2MME, B3GAT1
3eosin4410.1VIM, S100B
4edss4410.0S100B, MBP
5nogo-66 (1-40)5910.0MBP, S100B
6c3bot (154-182)5910.0S100B, MBP
7ono 25065910.0MBP, S100B
8mog (35-55)5910.0MBP, S100B
9plp (139-151)5910.0MBP, S100B
10olopatadine44 1110.9S100B, S100A1
112-methoxyethanol449.8ACTC1, VIM, S100A1
12actomyosin449.8ACTC1, S100A1, VIM
132,3-cyclic nucleotide449.8MBP, S100B
14toluidine449.7VIM, S100A1, DES
15orcein449.7DES, ACTC1, S100B, VIM
16s 100449.7VIM, S100B, DES, ACTC1
17reticulin449.7ACTC1, VIM, DES, S100B
18acetylcholine44 49 28 11 2413.6S100A1, MME, MBP
19bromodeoxyuridine449.6DES, MME, S100B, VIM
20ganglioside449.6DES, VIM, MBP
21adriamycin449.5MME, VIM, DES
22methionine449.5DES, MME, VIM, S100B
23silver449.5S100A1, MBP, DES
24cytarabine44 49 1111.5VIM, MBP, MME
25biotin44 11 2411.5DES, S100A1, VIM, ACTC1
26cocaine44 1110.3MBP, VIM, S100B
2712-o-tetradecanoylphorbol 13-acetate449.3VIM, MBP, DES, MME
28mucicarmine449.2VIM, S100B, ACTC1, DES, S100A1
29b 723449.2S100B, S100A1, DES, ACTC1, VIM
30hematoxylin449.2S100B, VIM, S100A1, DES, ACTC1
31cyclosporin a44 28 5911.2ACTC1, MME, MBP, S100B
32iron44 2410.2S100A1, ACTC1, S100B, VIM, DES
33forskolin44 49 1111.2MBP, MME, VIM, S100B
34vegf449.2DES, S100B, ACTC1, MME, VIM
35formaldehyde44 2410.1ACTC1, S100B, VIM, DES, MBP
36heparin44 28 11 2412.1MBP, VIM, DES, S100B, B3GAT1
37nitric oxide44 11 2411.0S100A1, S100B, DES, B3GAT1, MME
38lactate449.0MME, VIM, S100B, MBP, DES
39adenylate449.0S100B, MME, DES, MBP, VIM
40choline44 11 2411.0VIM, S100B, MBP
41testosterone44 59 11 2412.0VIM, S100B, ACTC1, MME, B3GAT1, DES
42thymidine44 249.9DES, MME, S100B, MBP
43creatinine448.8DES, MME, ACTC1, MBP, S100B, VIM
44arginine448.7MBP, VIM, MME, S100B, B3GAT1, DES
45glutamate448.7SLC1A6, VIM, MME, MBP, S100B
46cysteine448.6MME, DES, S100B, MBP, VIM, S100A1
47progesterone44 59 28 11 2412.6ACTC1, B3GAT1, MME, DES, S100A1, S100B
48paraffin448.3VIM, S100B, S100A1, MBP, DES, MME
49retinoic acid44 249.3MME, S100B, DES, MBP, S100A1, VIM
50tyrosine448.3DES, ACTC1, S100B, S100A1, MBP, MME

GO Terms for genes affiliated with Ossifying Fibromyxoid Tumor

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16Gene Ontology
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Biological processes related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of heart contractionGO:0080169.7DES, S100A1
2muscle filament slidingGO:0300499.2ACTC1, DES, VIM

Molecular functions related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:0445489.5S100A1, S100B
2identical protein bindingGO:0428029.1DES, S100A1, S100B, VIM

Products for genes affiliated with Ossifying Fibromyxoid Tumor

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Sources for Ossifying Fibromyxoid Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet