MCID: OSS002
MIFTS: 42

Ossifying Fibromyxoid Tumor malady

Cancer diseases category
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Summaries for Ossifying Fibromyxoid Tumor

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MalaCards based summary: Ossifying Fibromyxoid Tumor, also known as ossifying fibromyxoma, is related to endometrial stromal sarcoma and sarcoma. An important gene associated with Ossifying Fibromyxoid Tumor is S100B (S100 calcium binding protein B), and among its related pathways is Striated Muscle Contraction. The compounds fk 888 and edss have been mentioned in the context of this disorder. Affiliated tissues include bone, thyroid and breast, and related mouse phenotype behavior/neurological.

Aliases & Classifications for Ossifying Fibromyxoid Tumor

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Ossifying Fibromyxoid Tumor, Aliases & Descriptions:

Name: Ossifying Fibromyxoid Tumor 8 10 62
 
Ossifying Fibromyxoma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:2685
NCIt39 C6582

Related Diseases for Ossifying Fibromyxoid Tumor

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Diseases related to Ossifying Fibromyxoid Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1endometrial stromal sarcoma30.4DES, MME, ACTC1
2sarcoma30.1DES, ACTC1, S100A1, S100B, B3GAT1
3fibrous meningioma10.5S100B
4pineocytoma10.5S100B
5rosai-dorfman disease10.5S100B
6histiocytosis10.5S100B
7fasciitis10.5ACTC1
8osteosarcoma10.5
9ganglioglioma10.5S100B
10metanephric adenoma10.4B3GAT1
11infantile myofibromatosis10.4DES
12secondary progressive multiple sclerosis10.4MBP
13syringoma10.4S100A1, S100B
14langerhans-cell histiocytosis10.4S100A1, S100B
15papilloma10.3ACTC1
16malignant peripheral nerve sheath tumor10.3S100B, S100A1
17nasopharyngitis10.3
18extraosseous osteosarcoma10.3
19mediastinitis10.3
20thyroiditis10.3
21paraganglioma10.3S100B, S100A1
22mucoepidermoid carcinoma10.3ACTC1, S100A1
23epithelioid leiomyosarcoma10.2ACTC1, DES
24pseudosarcomatous fibromatosis10.2DES, ACTC1
25sex cord-gonadal stromal tumor10.2S100B, DES
26lipoma10.2DES, S100A1
27spindle cell carcinoma10.2ACTC1, DES
28desmoid tumor10.2ACTC1, DES
29rhabdoid tumor10.2ACTC1, DES
30microphthalmia10.2S100B, ACTC1
31embryonal rhabdomyosarcoma10.2DES, ACTC1
32synovial sarcoma10.2S100B, DES
33myoepithelioma10.2ACTC1, S100A1, S100B
34uterine fibroid10.2DES, S100A1
35salivary gland adenoid cystic carcinoma10.2S100B, S100A1, ACTC1
36oxyphilic adenoma10.2S100A1, MME
37tubular adenocarcinoma10.2MME, ACTC1
38renal clear cell carcinoma10.2MME, S100A1
39granular cell tumor10.2DES, S100A1, S100B
40idiopathic pulmonary fibrosis10.1S100A1, ACTC1
41malignant mesothelioma10.1DES, S100A1
42chordoma10.1DES, S100A1, S100B
43uterine sarcoma10.1MME, DES
44peripheral primitive neuroectodermal tumor10.1DES, S100A1, S100B
45chondrosarcoma10.1DES, S100A1, S100B
46angiomyolipoma10.1DES, ACTC1, S100A1
47fibroma10.1S100A1, ACTC1, DES
48follicular lymphoma10.1MME, S100A1
49fibromatosis10.1DES, ACTC1, S100A1
50spindle cell sarcoma10.1DES, ACTC1, S100B

Graphical network of the top 20 diseases related to Ossifying Fibromyxoid Tumor:



Diseases related to ossifying fibromyxoid tumor

Symptoms for Ossifying Fibromyxoid Tumor

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Drugs & Therapeutics for Ossifying Fibromyxoid Tumor

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Drug clinical trials:

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Search NIH Clinical Center for Ossifying Fibromyxoid Tumor

Genetic Tests for Ossifying Fibromyxoid Tumor

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Anatomical Context for Ossifying Fibromyxoid Tumor

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MalaCards organs/tissues related to Ossifying Fibromyxoid Tumor:

32
Bone, Thyroid, Breast, Skin, Testes, Tongue

Animal Models for Ossifying Fibromyxoid Tumor or affiliated genes

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MGI Mouse Phenotypes related to Ossifying Fibromyxoid Tumor:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.3MBP, B3GAT1, S100B, S100A1, DES

Publications for Ossifying Fibromyxoid Tumor

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Articles related to Ossifying Fibromyxoid Tumor:

(show top 50)    (show all 73)
idTitleAuthorsYear
1
Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors-molecular characterization shows genetic overlap with endometrial stromal sarcoma. (24285434)
2014
2
Ossifying fibromyxoid tumor metastatic to the thyroid: a case report and review of the literature. (24932821)
2014
3
Atypical ossifying fibromyxoid tumor. (25105387)
2014
4
PHF1 rearrangements in ossifying fibromyxoid tumors of soft parts: A fluorescence in situ hybridization study of 41 cases with emphasis on the malignant variant. (23887158)
2013
5
Extraosseous osteosarcoma arising in recurrent ossifying fibromyxoid tumor of soft tissue: a case report. (23805469)
2013
6
Ossifying fibromyxoid tumor presenting EP400-PHF1 fusion gene. (23806526)
2013
7
Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report. (23599783)
2013
8
Malignant ossifying fibromyxoid tumor of the parapharyngeal space. (23076857)
2012
9
Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors. (22796436)
2012
10
Cytological features of ossifying fibromyxoid tumor of soft parts. (23112466)
2012
11
Ossifying fibromyxoid tumor - Diagnostic challenge for a cytopathologist. (22919424)
2012
12
Osteopontin in ossifying fibromyxoid tumor. (21505404)
2011
13
Ossifying fibromyxoid tumor of head and neck region: case report and systematic review of literature. (20950910)
2011
14
Paraspinal malignant ossifying fibromyxoid tumor with spinal involvement. (20801659)
2010
15
Ossifying fibromyxoid tumor of soft parts mimicking a schwannoma with uncommon histology: a potential diagnostic pitfall. (19125736)
2009
16
Ossifying fibromyxoid tumor in the mandibular gingiva: case report and review of the literature. (19335090)
2009
17
Ossifying fibromyxoid tumor of soft parts--a clinicopathologic and immunohistochemical study of 104 cases with long-term follow-up and a critical review of the literature. (18469710)
2008
18
Ossifying fibromyxoid tumor of soft parts. Report of a rare tumor in Kuwait. (18523405)
2008
19
Sonographic features of an ossifying fibromyxoid tumor of the buttock. (18424660)
2008
20
Resection of metastatic pulmonary lesion of ossifying fibromyxoid tumor extending into the left atrium and ventricle via pulmonary vein. (16762602)
2007
21
Test and teach. An unusual supraclavicular lump. Ossifying fibromyxoid tumor. (17558865)
2007
22
Ossifying fibromyxoid tumor of soft parts with clonal chromosomal aberrations. (17656260)
2007
23
Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor. (16731174)
2006
24
Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst. (16919031)
2006
25
Subcutaneous ossifying fibromyxoid tumor. (17083695)
2006
26
Ossifying fibromyxoid tumor of the orbit. (16550049)
2006
27
Ossifying fibromyxoid tumor of the nasal septum. (16600550)
2006
28
Ossifying fibromyxoid tumor of the skin: a report of 2 cases with light microscopic, immunohistochemical, and electron microscopic characterization. (15793515)
2005
29
Cytologic diagnosis of ossifying fibromyxoid tumor of soft tissue: a case report. (14696144)
2004
30
Ossifying fibromyxoid tumor of the ethmoid sinus in a newborn: report of a case and literature review. (14725991)
2004
31
Ossifying fibromyxoid tumor of soft parts: a clinicopathologic study of 70 cases with emphasis on atypical and malignant variants. (12657926)
2003
32
Ossifying fibromyxoid tumor of soft parts. Cytogenetic findings. (11943338)
2002
33
Fine needle aspiration cytology of the malignant variant of ossifying fibromyxoid tumor of soft parts: a case report. (11575654)
2001
34
Ossifying fibromyxoid tumor of soft parts: a clinicopathological analysis of eight cases]. (11866971)
2001
35
Ossifying fibromyxoid tumor of soft parts: clinicopathologic, immunohistochemical and ultrastructural study of four cases. (10504543)
1999
36
Ossifying fibromyxoid tumor of soft parts in a child: a case report. (10466619)
1999
37
Ossifying fibromyxoid tumor resembling parosteal osteosarcoma. (9840396)
1998
38
Ossifying fibromyxoid tumor of soft parts: a report of 17 cases with emphasis on unusual histological features. (9869828)
1997
39
Radiographic appearance of an ossifying fibromyxoid tumor of soft parts. (9361359)
1997
40
Ossifying fibromyxoid tumor misdiagnosed as follicular neoplasia. A case report. (9990254)
1997
41
Ossifying fibromyxoid tumor of the retroperitoneum. (10846554)
1996
42
Ossifying fibromyxoid tumor of soft parts. (8864929)
1996
43
Nasopharyngeal nonossifying variant of ossifying fibromyxoid tumor: CT and MR findings. (7639139)
1995
44
New observations on three cases of ossifying fibromyxoid tumor of soft parts. (7953442)
1994
45
Ossifying subcutaneous tumor with myofibroblastic differentiation: a variant of ossifying fibromyxoid tumor of soft parts? (7804436)
1994
46
Self assessment--1993. Non-ossifying variant of ossifying fibromyxoid tumor of soft parts. (7699128)
1994
47
Ossifying fibromyxoid tumor of soft parts: a case report. (8459644)
1993
48
Case report 685: Ossifying fibromyxoid tumor of the soft parts of the upper arm. (1776029)
1991
49
Ossifying fibromyxoid tumor. Something new to mull over. (1899529)
1991
50
Ossifying fibromyxoid tumor. (2123607)
1990

Variations for Ossifying Fibromyxoid Tumor

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Expression for genes affiliated with Ossifying Fibromyxoid Tumor

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Expression patterns in normal tissues for genes affiliated with Ossifying Fibromyxoid Tumor

Search GEO for disease gene expression data for Ossifying Fibromyxoid Tumor.

Pathways for genes affiliated with Ossifying Fibromyxoid Tumor

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Pathways related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7ACTC1, DES

Compounds for genes affiliated with Ossifying Fibromyxoid Tumor

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Compounds related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1fk 8884410.0B3GAT1, MME
2edss4410.0S100B, MBP
3c3bot (154-182)6110.0S100B, MBP
4ono 25066110.0S100B, MBP
5nogo-66 (1-40)6110.0S100B, MBP
6mog (35-55)6110.0S100B, MBP
7plp (139-151)6110.0S100B, MBP
8olopatadine44 1110.9S100A1, S100B
92-methoxyethanol449.9S100A1, ACTC1
102,3-cyclic nucleotide449.9MBP, S100B
11orcein449.8S100B, ACTC1, DES
12s 100449.8S100B, ACTC1, DES
13reticulin449.8S100B, ACTC1, DES
14thiorphan44 28 1111.8B3GAT1, MME
15toluidine449.8S100A1, DES
16imatinib44 50 1111.7DES, ACTC1, S100B
17bromodeoxyuridine449.6S100B, MME, DES
18biotin44 24 1111.5S100A1, ACTC1, DES
19acth449.5MME, S100B, B3GAT1
20silver449.4MBP, S100A1, DES
21mucicarmine449.3S100B, S100A1, ACTC1, DES
22b 723449.3DES, ACTC1, S100A1, S100B
23hematoxylin449.3DES, ACTC1, S100A1, S100B
24actomyosin449.3ACTC1, S100A1
25formaldehyde44 2410.3DES, ACTC1, S100B, MBP
26methionine449.3DES, MME, S100B
27glycogen44 2410.3DES, ACTC1, S100A1, S100B
28iron44 2410.2DES, ACTC1, S100A1, S100B
29norepinephrine44 24 1111.2MBP, S100B, DES
30cyclosporin a44 28 6111.2MME, ACTC1, S100B, MBP
31heparin44 28 24 1112.2MBP, B3GAT1, S100B, DES
3212-o-tetradecanoylphorbol 13-acetate449.2MBP, MME, DES
33steroid449.1DES, MME, ACTC1, S100B
34lactate449.1DES, MME, S100B, MBP
35thymidine44 2410.1DES, MME, S100B, MBP
36adenylate449.1DES, MME, S100B, MBP
37vegf449.1DES, MME, ACTC1, S100B
38testosterone44 61 24 1112.0B3GAT1, S100B, ACTC1, MME, DES
39creatinine448.8DES, MME, ACTC1, S100B, MBP
40oxygen44 249.8S100B, ACTC1, MME, DES
41arginine448.8DES, MME, S100B, B3GAT1, MBP
42nitric oxide44 24 1110.8DES, MME, S100A1, S100B, B3GAT1
43acetylcholine44 50 28 24 1112.7DES, MME, S100A1, S100B, MBP
44cysteine448.6MBP, S100B, S100A1, MME, DES
45progesterone44 28 61 24 1112.5DES, MME, ACTC1, S100A1, S100B, B3GAT1
46calcium44 50 24 1111.4DES, MME, ACTC1, S100A1, S100B, B3GAT1
47paraffin448.3DES, MME, ACTC1, S100A1, S100B, MBP
48retinoic acid44 249.3DES, MME, ACTC1, S100A1, S100B, MBP
49tyrosine448.3DES, MME, ACTC1, S100A1, S100B, MBP
50estrogen448.0DES, MME, ACTC1, S100A1, S100B, B3GAT1

GO Terms for genes affiliated with Ossifying Fibromyxoid Tumor

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Biological processes related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of heart contractionGO:0080169.4S100A1, DES
2substantia nigra developmentGO:0217629.4MBP, S100A1
3muscle filament slidingGO:0300499.4ACTC1, DES

Molecular functions related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:0445489.5S100B, S100A1
2calcium-dependent protein bindingGO:0483069.3S100B, S100A1
3identical protein bindingGO:0428029.2S100B, S100A1, DES

Products for genes affiliated with Ossifying Fibromyxoid Tumor

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Sources for Ossifying Fibromyxoid Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet