MCID: OSS002
MIFTS: 39

Ossifying Fibromyxoid Tumor malady

Cancer diseases category

Summaries for Ossifying Fibromyxoid Tumor

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32MalaCards
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MalaCards: Ossifying Fibromyxoid Tumor, also known as ossifying fibromyxoma, is related to endometrial stromal sarcoma and sarcoma. An important gene associated with Ossifying Fibromyxoid Tumor is S100B (S100 calcium binding protein B), and among its related pathways is Striated Muscle Contraction. The compounds glycogen and fk 888 have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and testes.

Aliases & Classifications for Ossifying Fibromyxoid Tumor

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

ossifying fibromyxoid tumor 8 10 60
ossifying fibromyxoma 8


External Ids:

Disease Ontology8 DOID:2685
NCIt39 C6582

Related Diseases for Ossifying Fibromyxoid Tumor

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17GeneCards, 18GeneDecks
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Diseases related to Ossifying Fibromyxoid Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 107)
idRelated DiseaseScoreTop Affiliating Genes
1endometrial stromal sarcoma30.3VIM, DES, ACTC1, MME
2sarcoma30.3DES, ACTC1, B3GAT1, VIM, S100B, CREB3L2
3osteosarcoma10.4
4nonossifying fibromyxoid tumor10.2
5nasopharyngitis10.2
6endometrial stromal tumor10.2
7extraosseous osteosarcoma10.2
8mediastinitis10.2
9hemangioblastoma10.0S100B
10histiocytosis10.0S100B
11fasciitis10.0ACTC1
12lymphangioleiomyomatosis10.0DES
13metanephric adenoma10.0B3GAT1
14teratoma10.0ACTC1
15renal oncocytoma10.0S100A1
16infantile myofibromatosis10.0DES
17fibrous meningioma10.0S100B
18neurilemmoma10.0B3GAT1
19pilocytic astrocytoma10.0S100B
20papilloma10.0ACTC1
21germ cell cancer10.0B3GAT1
22pineocytoma10.0S100B
23rosai-dorfman disease10.0S100B
24cystadenoma10.0MME
25glomerulonephritis10.0MME
26endometrial carcinoma10.0MME
27oxyphilic adenoma10.0S100A1
28extraskeletal myxoid chondrosarcoma10.0CREB3L2
29hemangioma10.0ACTC1
30paraganglioma10.0S100B, S100A1
31syringoma10.0S100A1, S100B
32ischemia10.0MME
33pneumonia10.0MME
34ganglioneuroblastoma10.0S100B
35endometriosis10.0ACTC1
36langerhans-cell histiocytosis10.0S100B, S100A1
37lipoma10.0DES, S100A1
38adenomatoid tumor10.0VIM
39congestive heart failure10.0MME
40desmoid tumor10.0ACTC1, DES
41perineurioma10.0VIM, S100B
42angiosarcoma10.0VIM, ACTC1
43embryonal rhabdomyosarcoma10.0DES, ACTC1
44liposarcoma10.0VIM, DES
45myopathy10.0DES
46mesenchymal chondrosarcoma10.0DES, VIM
47tubular adenocarcinoma10.0ACTC1, MME
48adenoma10.0ACTC1, B3GAT1, S100A1
49alveolar soft part sarcoma10.0VIM, DES
50malignant mixed mullerian tumor10.0MME, VIM

Graphical network of the top 20 diseases related to Ossifying Fibromyxoid Tumor:



Diseases related to ossifying fibromyxoid tumor

Clinical Features for Ossifying Fibromyxoid Tumor

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Drugs & Therapeutics for Ossifying Fibromyxoid Tumor

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ossifying Fibromyxoid Tumor

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Anatomical Context for Ossifying Fibromyxoid Tumor

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32MalaCards
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MalaCards organs/tissues related to Ossifying Fibromyxoid Tumor:

32
Bone, Skin, Testes, Tongue

Animal Models for Ossifying Fibromyxoid Tumor or affiliated genes

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Publications for Ossifying Fibromyxoid Tumor

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50PubMed
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Articles related to Ossifying Fibromyxoid Tumor:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors-molecular characterization shows genetic overlap with endometrial stromal sarcoma. (24285434)
2014
2
Extraosseous osteosarcoma arising in recurrent ossifying fibromyxoid tumor of soft tissue: a case report. (23805469)
2013
3
Ossifying fibromyxoid tumor presenting EP400-PHF1 fusion gene. (23806526)
2013
4
Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report. (23599783)
2013
5
Malignant ossifying fibromyxoid tumor of the tongue: case report and review of the literature. (23800162)
2013
6
Malignant ossifying fibromyxoid tumor of the parapharyngeal space. (23076857)
2012
7
Ossifying fibromyxoid tumor - Diagnostic challenge for a cytopathologist. (22919424)
2012
8
Osteopontin in ossifying fibromyxoid tumor. (21505404)
2011
9
Ossifying fibromyxoid tumor of head and neck region: case report and systematic review of literature. (20950910)
2011
10
Ossifying fibromyxoid tumor of soft parts: a clinicopathologic, proteomic, and genomic study. (21997683)
2011
11
Paraspinal malignant ossifying fibromyxoid tumor with spinal involvement. (20801659)
2010
12
Ossifying fibromyxoid tumor in the mandibular gingiva: case report and review of the literature. (19335090)
2009
13
Ossifying fibromyxoid tumor with atypical histological features: a case report. (20387713)
2009
14
Ossifying fibromyxoid tumor of soft parts--a clinicopathologic and immunohistochemical study of 104 cases with long-term follow-up and a critical review of the literature. (18469710)
2008
15
Ossifying fibromyxoid tumor of soft parts. Report of a rare tumor in Kuwait. (18523405)
2008
16
Sonographic features of an ossifying fibromyxoid tumor of the buttock. (18424660)
2008
17
Ossifying fibromyxoid tumor of oral cavity. (18460251)
2008
18
Resection of metastatic pulmonary lesion of ossifying fibromyxoid tumor extending into the left atrium and ventricle via pulmonary vein. (16762602)
2007
19
Test and teach. An unusual supraclavicular lump. Ossifying fibromyxoid tumor. (17558865)
2007
20
Ossifying fibromyxoid tumor of soft parts with clonal chromosomal aberrations. (17656260)
2007
21
Ossifying fibromyxoid tumor may express CD56 and CD99: a case report. (17913956)
2007
22
Cutaneous malignant ossifying fibromyxoid tumor. (17414437)
2007
23
Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor. (16731174)
2006
24
Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst. (16919031)
2006
25
Subcutaneous ossifying fibromyxoid tumor. (17083695)
2006
26
Ossifying fibromyxoid tumor of the orbit. (16550049)
2006
27
Ossifying fibromyxoid tumor of the skin: a report of 2 cases with light microscopic, immunohistochemical, and electron microscopic characterization. (15793515)
2005
28
Ossifying fibromyxoid tumor of the ethmoid sinus in a newborn: report of a case and literature review. (14725991)
2004
29
Ossifying fibromyxoid tumor of soft parts: a clinicopathologic study of 70 cases with emphasis on atypical and malignant variants. (12657926)
2003
30
Ossifying fibromyxoid tumor of soft parts. Cytogenetic findings. (11943338)
2002
31
Ossifying fibromyxoid tumor of soft parts: clinicopathologic, immunohistochemical and ultrastructural study of four cases. (10504543)
1999
32
Ossifying fibromyxoid tumor of soft parts in a child: a case report. (10466619)
1999
33
Ossifying fibromyxoid tumor resembling parosteal osteosarcoma. (9840396)
1998
34
Ossifying fibromyxoid tumor of soft parts: a report of 17 cases with emphasis on unusual histological features. (9869828)
1997
35
Radiographic appearance of an ossifying fibromyxoid tumor of soft parts. (9361359)
1997
36
Ossifying fibromyxoid tumor of soft parts. (8864929)
1996
37
Ossifying fibromyxoid tumor of soft parts: a case report and review. (8864928)
1996
38
Ossifying fibromyxoid tumor of soft parts of the back. (8864930)
1996
39
Pathologic quiz case 2. Ossifying fibromyxoid tumor. (7576484)
1995
40
Atypical and malignant variants of ossifying fibromyxoid tumor. Clinicopathologic analysis of six cases. (7661277)
1995
41
New observations on three cases of ossifying fibromyxoid tumor of soft parts. (7953442)
1994
42
Ossifying subcutaneous tumor with myofibroblastic differentiation: a variant of ossifying fibromyxoid tumor of soft parts? (7804436)
1994
43
Self assessment--1993. Non-ossifying variant of ossifying fibromyxoid tumor of soft parts. (7699128)
1994
44
Ossifying fibromyxoid tumor of soft parts with stromal cyst formation and ribosome-lamella complexes. (7855933)
1994
45
Ossifying fibromyxoid tumor of soft parts: a morphological and immunohistochemical study. (8055111)
1994
46
Ossifying fibromyxoid tumor of soft parts: a case report. (8459644)
1993
47
Case report 685: Ossifying fibromyxoid tumor of the soft parts of the upper arm. (1776029)
1991
48
Ossifying fibromyxoid tumor. Something new to mull over. (1899529)
1991
49
Ossifying fibromyxoid tumor of soft parts. Additional observations of a distinctive soft tissue tumor. (1704177)
1991
50
Ossifying fibromyxoid tumor of soft parts. A clinicopathological analysis of 59 cases. (2476942)
1989

Genetic Variations for Ossifying Fibromyxoid Tumor

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Expression for genes affiliated with Ossifying Fibromyxoid Tumor

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ossifying Fibromyxoid Tumor

Search GEO for disease gene expression data for Ossifying Fibromyxoid Tumor.

Pathways for genes affiliated with Ossifying Fibromyxoid Tumor

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37NCBI BioSystems Database, 53Reactome
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Pathways related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.5ACTC1, DES, VIM

Compounds for genes affiliated with Ossifying Fibromyxoid Tumor

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44Novoseek, 24HMDB, 59Tocris Bioscience, 11DrugBank, 49PharmGKB, 28IUPHAR
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Compounds related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idCompoundScoreTop Affiliating Genes
1glycogen44 2411.6ACTC1
2fk 8884410.2MME, B3GAT1
3eosin4410.1S100B, VIM
4edss4410.0MBP, S100B
5c3bot (154-182)5910.0S100B, MBP
6ono 25065910.0S100B, MBP
7nogo-66 (1-40)5910.0S100B, MBP
8mog (35-55)5910.0S100B, MBP
9plp (139-151)5910.0S100B, MBP
10olopatadine44 1110.9S100A1, S100B
112-methoxyethanol449.8ACTC1, S100A1, VIM
12actomyosin449.8ACTC1, S100A1, VIM
132,3-cyclic nucleotide449.8S100B, MBP
14toluidine449.7DES, S100A1, VIM
15orcein449.7VIM, S100B, DES, ACTC1
16s 100449.7ACTC1, DES, S100B, VIM
17reticulin449.7ACTC1, DES, S100B, VIM
18acetylcholine44 49 28 11 2413.6MME, MBP, S100A1
19bromodeoxyuridine449.6VIM, S100B, DES, MME
20ganglioside449.6VIM, MBP, DES
21adriamycin449.5MME, DES, VIM
22methionine449.5VIM, S100B, DES, MME
23silver449.5DES, MBP, S100A1
24cytarabine44 49 1111.5MME, MBP, VIM
25biotin44 11 2411.5VIM, S100A1, DES, ACTC1
26cocaine44 1110.3MBP, S100B, VIM
2712-o-tetradecanoylphorbol 13-acetate449.3VIM, MBP, DES, MME
28mucicarmine449.2ACTC1, DES, S100A1, S100B, VIM
29b 723449.2VIM, S100B, S100A1, DES, ACTC1
30hematoxylin449.2VIM, S100B, S100A1, DES, ACTC1
31cyclosporin a44 28 5911.2S100B, MBP, MME, ACTC1
32iron44 2410.2VIM, S100B, S100A1, DES, ACTC1
33forskolin44 49 1111.2VIM, S100B, MBP, MME
34vegf449.2VIM, S100B, DES, MME, ACTC1
35formaldehyde44 2410.1VIM, S100B, MBP, DES, ACTC1
36heparin44 28 11 2412.1VIM, S100B, MBP, DES, B3GAT1
37nitric oxide44 11 2411.0MME, B3GAT1, DES, S100A1, S100B
38lactate449.0VIM, S100B, MBP, DES, MME
39adenylate449.0VIM, S100B, MBP, DES, MME
40choline44 11 2411.0MBP, S100B, VIM
41testosterone44 59 11 2412.0VIM, S100B, DES, B3GAT1, MME, ACTC1
42thymidine44 249.9S100B, MBP, DES, MME
43creatinine448.8VIM, S100B, MBP, DES, MME, ACTC1
44arginine448.7VIM, S100B, MBP, DES, B3GAT1, MME
45glutamate448.7VIM, S100B, MBP, MME, SLC1A6
46cysteine448.6VIM, S100B, S100A1, MBP, DES, MME
47progesterone44 59 28 11 2412.6VIM, S100B, S100A1, DES, B3GAT1, MME
48paraffin448.3VIM, S100B, S100A1, MBP, DES, MME
49retinoic acid44 249.3VIM, S100B, S100A1, MBP, DES, MME
50tyrosine448.3S100A1, MBP, DES, MME, ACTC1, S100B

GO Terms for genes affiliated with Ossifying Fibromyxoid Tumor

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16Gene Ontology
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Biological processes related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of heart contractionGO:0080169.7DES, S100A1
2muscle filament slidingGO:0300499.2ACTC1, DES, VIM

Molecular functions related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:0445489.5S100A1, S100B
2identical protein bindingGO:0428029.1DES, S100A1, S100B, VIM

Products for genes affiliated with Ossifying Fibromyxoid Tumor

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Sources for Ossifying Fibromyxoid Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet