MCID: OSS002
MIFTS: 41

Ossifying Fibromyxoid Tumor malady

Cancer diseases category

Summaries for Ossifying Fibromyxoid Tumor

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34MalaCards
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MalaCards: Ossifying Fibromyxoid Tumor, also known as ossifying fibromyxoma, is related to endometrial stromal sarcoma and sarcoma. An important gene associated with Ossifying Fibromyxoid Tumor is S100B (S100 calcium binding protein B), and among its related pathways is Striated Muscle Contraction. The compounds fk 888 and edss have been mentioned in the context of this disorder. Affiliated tissues include skin, tongue and bone, and related mouse phenotype behavior/neurological.

Aliases & Classifications for Ossifying Fibromyxoid Tumor

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9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

ossifying fibromyxoid tumor 9 11 63
ossifying fibromyxoma 9


External Ids:

Disease Ontology9 DOID:2685
NCIt41 C6582

Related Diseases for Ossifying Fibromyxoid Tumor

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18GeneCards, 19GeneDecks
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Diseases related to Ossifying Fibromyxoid Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 80)
idRelated DiseaseScoreTop Affiliating Genes
1endometrial stromal sarcoma30.4DES, MME, ACTC1
2sarcoma30.4DES, ACTC1, S100A1, S100B, B3GAT1
3osteosarcoma10.4
4nasopharyngitis10.3
5extraosseous osteosarcoma10.3
6mediastinitis10.3
7fibrous meningioma10.1S100B
8pineocytoma10.1S100B
9rosai-dorfman disease10.1S100B
10histiocytosis10.1S100B
11fasciitis10.1ACTC1
12ganglioglioma10.1S100B
13metanephric adenoma10.1B3GAT1
14infantile myofibromatosis10.1DES
15secondary progressive multiple sclerosis10.1MBP
16syringoma10.1S100A1, S100B
17langerhans-cell histiocytosis10.1S100A1, S100B
18papilloma10.1ACTC1
19malignant peripheral nerve sheath tumor10.1S100B, S100A1
20paraganglioma10.1S100B, S100A1
21mucoepidermoid carcinoma10.1ACTC1, S100A1
22epithelioid leiomyosarcoma10.1ACTC1, DES
23pseudosarcomatous fibromatosis10.1DES, ACTC1
24sex cord-gonadal stromal tumor10.1S100B, DES
25lipoma10.1DES, S100A1
26spindle cell carcinoma10.1ACTC1, DES
27desmoid tumor10.1ACTC1, DES
28rhabdoid tumor10.0ACTC1, DES
29microphthalmia10.0S100B, ACTC1
30embryonal rhabdomyosarcoma10.0DES, ACTC1
31synovial sarcoma10.0S100B, DES
32myoepithelioma10.0ACTC1, S100A1, S100B
33uterine fibroid10.0DES, S100A1
34adenoid cystic carcinoma10.0S100B, S100A1, ACTC1
35oxyphilic adenoma10.0S100A1, MME
36tubular adenocarcinoma10.0MME, ACTC1
37renal clear cell carcinoma10.0MME, S100A1
38granular cell tumor10.0DES, S100A1, S100B
39idiopathic pulmonary fibrosis10.0S100A1, ACTC1
40malignant mesothelioma10.0DES, S100A1
41chordoma10.0DES, S100A1, S100B
42uterine sarcoma10.0MME, DES
43glomus tumor10.0DES, ACTC1, S100A1
44peripheral primitive neuroectodermal tumor10.0DES, S100A1, S100B
45chondrosarcoma10.0DES, S100A1, S100B
46angiomyolipoma10.0DES, ACTC1, S100A1
47fibroma10.0S100A1, ACTC1, DES
48follicular lymphoma10.0MME, S100A1
49fibromatosis10.0DES, ACTC1, S100A1
50spindle cell sarcoma10.0DES, ACTC1, S100B

Graphical network of the top 20 diseases related to Ossifying Fibromyxoid Tumor:



Diseases related to ossifying fibromyxoid tumor

Symptoms for Ossifying Fibromyxoid Tumor

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Drugs & Therapeutics for Ossifying Fibromyxoid Tumor

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ossifying Fibromyxoid Tumor

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Anatomical Context for Ossifying Fibromyxoid Tumor

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34MalaCards
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MalaCards organs/tissues related to Ossifying Fibromyxoid Tumor:

34
Skin, Tongue, Bone, Testes

Animal Models for Ossifying Fibromyxoid Tumor or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Ossifying Fibromyxoid Tumor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.3MBP, B3GAT1, S100B, S100A1, DES

Publications for Ossifying Fibromyxoid Tumor

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53PubMed
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Articles related to Ossifying Fibromyxoid Tumor:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors-molecular characterization shows genetic overlap with endometrial stromal sarcoma. (24285434)
2014
2
Extraosseous osteosarcoma arising in recurrent ossifying fibromyxoid tumor of soft tissue: a case report. (23805469)
2013
3
Ossifying fibromyxoid tumor presenting EP400-PHF1 fusion gene. (23806526)
2013
4
Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report. (23599783)
2013
5
Malignant ossifying fibromyxoid tumor of the tongue: case report and review of the literature. (23800162)
2013
6
Malignant ossifying fibromyxoid tumor of the parapharyngeal space. (23076857)
2012
7
Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors. (22796436)
2012
8
Cytological features of ossifying fibromyxoid tumor of soft parts. (23112466)
2012
9
Ossifying fibromyxoid tumor - Diagnostic challenge for a cytopathologist. (22919424)
2012
10
Osteopontin in ossifying fibromyxoid tumor. (21505404)
2011
11
Ossifying fibromyxoid tumor of head and neck region: case report and systematic review of literature. (20950910)
2011
12
Paraspinal malignant ossifying fibromyxoid tumor with spinal involvement. (20801659)
2010
13
Ossifying fibromyxoid tumor of soft parts mimicking a schwannoma with uncommon histology: a potential diagnostic pitfall. (19125736)
2009
14
Ossifying fibromyxoid tumor in the mandibular gingiva: case report and review of the literature. (19335090)
2009
15
Ossifying fibromyxoid tumor of soft parts--a clinicopathologic and immunohistochemical study of 104 cases with long-term follow-up and a critical review of the literature. (18469710)
2008
16
Ossifying fibromyxoid tumor of soft parts. Report of a rare tumor in Kuwait. (18523405)
2008
17
Sonographic features of an ossifying fibromyxoid tumor of the buttock. (18424660)
2008
18
Resection of metastatic pulmonary lesion of ossifying fibromyxoid tumor extending into the left atrium and ventricle via pulmonary vein. (16762602)
2007
19
Test and teach. An unusual supraclavicular lump. Ossifying fibromyxoid tumor. (17558865)
2007
20
Ossifying fibromyxoid tumor of soft parts with clonal chromosomal aberrations. (17656260)
2007
21
Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor. (16731174)
2006
22
Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst. (16919031)
2006
23
Subcutaneous ossifying fibromyxoid tumor. (17083695)
2006
24
Ossifying fibromyxoid tumor of the orbit. (16550049)
2006
25
Ossifying fibromyxoid tumor of the nasal septum. (16600550)
2006
26
An unusual presentation of ossifying fibromyxoid tumor of the mandible: a case report. (17315811)
2006
27
Ossifying fibromyxoid tumor of the skin: a report of 2 cases with light microscopic, immunohistochemical, and electron microscopic characterization. (15793515)
2005
28
Cytologic diagnosis of ossifying fibromyxoid tumor of soft tissue: a case report. (14696144)
2004
29
Ossifying fibromyxoid tumor of the ethmoid sinus in a newborn: report of a case and literature review. (14725991)
2004
30
Ossifying fibromyxoid tumor of soft parts: a clinicopathologic study of 70 cases with emphasis on atypical and malignant variants. (12657926)
2003
31
Ossifying fibromyxoid tumor of soft parts. Cytogenetic findings. (11943338)
2002
32
Fine needle aspiration cytology of the malignant variant of ossifying fibromyxoid tumor of soft parts: a case report. (11575654)
2001
33
Ossifying fibromyxoid tumor of soft parts: a clinicopathological analysis of eight cases]. (11866971)
2001
34
Ossifying fibromyxoid tumor of soft parts: clinicopathologic, immunohistochemical and ultrastructural study of four cases. (10504543)
1999
35
Ossifying fibromyxoid tumor of soft parts in a child: a case report. (10466619)
1999
36
Ossifying fibromyxoid tumor resembling parosteal osteosarcoma. (9840396)
1998
37
Ossifying fibromyxoid tumor of soft parts: a report of 17 cases with emphasis on unusual histological features. (9869828)
1997
38
Radiographic appearance of an ossifying fibromyxoid tumor of soft parts. (9361359)
1997
39
Ossifying fibromyxoid tumor misdiagnosed as follicular neoplasia. A case report. (9990254)
1997
40
Ossifying fibromyxoid tumor of the retroperitoneum. (10846554)
1996
41
Ossifying fibromyxoid tumor of soft parts. (8864929)
1996
42
Nasopharyngeal nonossifying variant of ossifying fibromyxoid tumor: CT and MR findings. (7639139)
1995
43
Pathologic quiz case 2. Ossifying fibromyxoid tumor. (7576484)
1995
44
New observations on three cases of ossifying fibromyxoid tumor of soft parts. (7953442)
1994
45
Ossifying subcutaneous tumor with myofibroblastic differentiation: a variant of ossifying fibromyxoid tumor of soft parts? (7804436)
1994
46
Self assessment--1993. Non-ossifying variant of ossifying fibromyxoid tumor of soft parts. (7699128)
1994
47
Ossifying fibromyxoid tumor of soft parts: a case report. (8459644)
1993
48
Case report 685: Ossifying fibromyxoid tumor of the soft parts of the upper arm. (1776029)
1991
49
Ossifying fibromyxoid tumor. Something new to mull over. (1899529)
1991
50
Ossifying fibromyxoid tumor. (2123607)
1990

Variations for Ossifying Fibromyxoid Tumor

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Expression for genes affiliated with Ossifying Fibromyxoid Tumor

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ossifying Fibromyxoid Tumor

Search GEO for disease gene expression data for Ossifying Fibromyxoid Tumor.

Pathways for genes affiliated with Ossifying Fibromyxoid Tumor

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51PathCards, 39NCBI BioSystems Database, 56Reactome
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Pathways related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7ACTC1, DES

Compounds for genes affiliated with Ossifying Fibromyxoid Tumor

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46Novoseek, 62Tocris Bioscience, 12DrugBank, 30IUPHAR, 52PharmGKB, 25HMDB
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Compounds related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1fk 8884610.0B3GAT1, MME
2edss4610.0S100B, MBP
3c3bot (154-182)6210.0S100B, MBP
4ono 25066210.0MBP, S100B
5nogo-66 (1-40)6210.0S100B, MBP
6mog (35-55)6210.0S100B, MBP
7plp (139-151)6210.0S100B, MBP
8olopatadine46 1210.9S100B, S100A1
92-methoxyethanol469.9S100A1, ACTC1
102,3-cyclic nucleotide469.9MBP, S100B
11orcein469.8S100B, DES, ACTC1
12s 100469.8ACTC1, DES, S100B
13reticulin469.8S100B, ACTC1, DES
14thiorphan46 30 1211.8MME, B3GAT1
15toluidine469.8S100A1, DES
16imatinib46 52 1211.7DES, ACTC1, S100B
17bromodeoxyuridine469.6MME, DES, S100B
18biotin46 25 1211.5DES, ACTC1, S100A1
19acth469.5S100B, B3GAT1, MME
20silver469.4MBP, S100A1, DES
21mucicarmine469.3ACTC1, S100B, S100A1, DES
22b 723469.3ACTC1, DES, S100B, S100A1
23hematoxylin469.3S100A1, DES, ACTC1, S100B
24actomyosin469.3ACTC1, S100A1
25formaldehyde46 2510.3DES, S100B, MBP, ACTC1
26methionine469.3S100B, MME, DES
27glycogen46 2510.3DES, S100B, S100A1, ACTC1
28iron46 2510.2DES, ACTC1, S100A1, S100B
29norepinephrine46 25 1211.2MBP, DES, S100B
30cyclosporin a46 30 6211.2MME, ACTC1, S100B, MBP
31heparin46 30 25 1212.2MBP, S100B, DES, B3GAT1
3212-o-tetradecanoylphorbol 13-acetate469.2DES, MME, MBP
33steroid469.1MME, DES, ACTC1, S100B
34lactate469.1DES, MBP, S100B, MME
35thymidine46 2510.1DES, MBP, MME, S100B
36adenylate469.1DES, MME, S100B, MBP
37vegf469.1S100B, DES, ACTC1, MME
38testosterone46 62 25 1212.0S100B, MME, DES, B3GAT1, ACTC1
39creatinine468.8S100B, DES, MME, ACTC1, MBP
40oxygen46 259.8DES, MME, S100B, ACTC1
41arginine468.8B3GAT1, S100B, MME, DES, MBP
42nitric oxide46 25 1210.8DES, MME, S100B, B3GAT1, S100A1
43acetylcholine46 52 30 25 1212.7S100A1, S100B, MBP, MME, DES
44cysteine468.6DES, MBP, S100B, S100A1, MME
45progesterone46 30 62 25 1212.5ACTC1, DES, MME, S100A1, S100B, B3GAT1
46calcium46 52 25 1211.4S100A1, B3GAT1, MME, DES, S100B, ACTC1
47paraffin468.3S100B, ACTC1, MBP, MME, DES, S100A1
48retinoic acid46 259.3MME, S100A1, ACTC1, S100B, MBP, DES
49tyrosine468.3ACTC1, DES, MBP, MME, S100B, S100A1
50estrogen468.0DES, MME, ACTC1, S100B, MBP, B3GAT1

GO Terms for genes affiliated with Ossifying Fibromyxoid Tumor

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17Gene Ontology
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Biological processes related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of heart contractionGO:0080169.4S100A1, DES
2substantia nigra developmentGO:0217629.4MBP, S100A1
3muscle filament slidingGO:0300499.4ACTC1, DES

Molecular functions related to Ossifying Fibromyxoid Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:0445489.5S100B, S100A1
2calcium-dependent protein bindingGO:0483069.3S100B, S100A1
3identical protein bindingGO:0428029.2S100B, S100A1, DES

Products for genes affiliated with Ossifying Fibromyxoid Tumor

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  • Antibodies
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Sources for Ossifying Fibromyxoid Tumor

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet