Aliases & Classifications for Osteitis Fibrosa

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Aliases & Descriptions for Osteitis Fibrosa:

Name: Osteitis Fibrosa 11 50 13
Osteitis Fibrosa Cystica 39 68
Osteitis Fibrosa Cystica Generalisata 11
 
Von Recklinghausen's Bone Disease 11
Hyperparathyroid Bone Disease 11
Osteitis Fibrosa Disseminata 68

Classifications:



External Ids:

Disease Ontology11 DOID:3341
MeSH39 D010002
NCIt45 C34875

Summaries for Osteitis Fibrosa

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Disease Ontology:11 A bone resorption disease that has material basis in hyperparathyroidism which results in hyperactivity in osteoclasts, deformity, and loss of mass located in bone.

MalaCards based summary: Osteitis Fibrosa, also known as osteitis fibrosa cystica, is related to pseudohypoparathyroidism, type ib and cranial nerve palsy, and has symptoms including uraemia odour An important gene associated with Osteitis Fibrosa is BGLAP (Bone Gamma-Carboxyglutamate Protein), and among its related pathways are Glucocorticoid receptor regulatory network and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include bone, bone and bone marrow.

Related Diseases for Osteitis Fibrosa

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Diseases related to Osteitis Fibrosa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1pseudohypoparathyroidism, type ib31.5GNAS, PTH
2cranial nerve palsy30.2BGLAP, PTH
3renal osteodystrophy11.4
4mccune-albright syndrome, somatic, mosaic11.3
5monostotic fibrous dysplasia11.1
6hyperparathyroidism10.6
7adenoma10.4
8nodular goiter10.4BGLAP, CALCA
9parathyroid adenoma10.4
10scrotal carcinoma10.3BGLAP, CALCA
11meningococcal meningitis10.3CALCA, IL6
12achondrogenesis10.3BGLAP, PTH
13weaver syndrome 110.3BGLAP, PTH
14bullous pemphigoid10.3CALCA, IL6
15acute salpingo-oophoritis10.3BGLAP, CALCA
16substernal goiter10.3CALCA, IL6
17hypochondrogenesis10.3CALCA, PTH
18silver-russell syndrome due to 7p11.2p13 microduplication10.3BGLAP, CASR
19periodic paralyses10.3CALCA, IL6
20osteomalacia10.2
21gestational diabetes10.2BGLAP, PTH
22impotence10.2CALCA, PTH
23polyradiculopathy10.2CALCA, PTH
24gastric dilatation10.2CALCA, IL6
25anal buschke-lowenstein tumor10.2CALCA, PTH
26sternum lymphoma10.2BGLAP, IL6
27toenail dystrophy, isolated10.2CALCA, PTH
28commensal bacterial infectious disease10.2BGLAP, PTH
29pseudohypoparathyroidism10.2
30reproductive organ cancer10.1BGLAP, IL6
31ovarian insufficiency, familial10.1BGLAP, PTH
32central nervous system hemangioma10.1CALCA, PTH
33xanthomatosis10.1BGLAP, IL6
34giant cell tumor10.1
35thyroiditis10.1
36echinostomiasis10.1BGLAP, CALCA
37testicular brenner tumor10.1CASR, PTH
38solitary bone cyst10.0
39rickets10.0
40chronic myelomonocytic leukemia10.0CALCA, PTH
41parathyroid transitional clear cell adenoma10.0BGLAP, CALCA, PTH
42dyscalculia10.0BGLAP, CALCA, PTH
43bacillary angiomatosis10.0BGLAP, CALCA, PTH
44bone deterioration disease10.0BGLAP, CALCA, PTH
45meningovascular neurosyphilis9.9CALCA, GNAS
46cannabis dependence9.9BGLAP, IL6
47gemistocytic astrocytoma9.9BGLAP, IL6, PTH
48exocrine pancreatic insufficiency9.9IL6, PTH
49hyperparathyroidism-jaw tumor syndrome9.9
50osteoporosis9.9

Graphical network of the top 20 diseases related to Osteitis Fibrosa:



Diseases related to osteitis fibrosa

Symptoms & Phenotypes for Osteitis Fibrosa

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UMLS symptoms related to Osteitis Fibrosa:


uraemia odour

Drugs & Therapeutics for Osteitis Fibrosa

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Drugs for Osteitis Fibrosa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Etidronic acidapprovedPhase 2, Phase 3827414-83-7, 2809-21-43305
Synonyms:
(1-Hydroxyethylene)diphosphonic acid
(1-Hydroxyethylidene)bis(phosphonic acid)
(1-Hydroxyethylidene)bisphosphonic acid
(1-Hydroxyethylidene)diphoshonic acid
(1-Hydroxyethylidene)diphosphonic acid
(1-hydroxy-1-phosphonoethyl)phosphonic acid
(1-hydroxy-ethylidene)diphosphonic acid
(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)
(Hydroxyethylidene)diphosphonic acid
0-02-00-00171 (Beilstein Handbook Reference)
1,1,1-Ethanetriol diphosphonate
1-HYDROXY-1,1-DIPHOSPHONOETHANE
1-Hydroxy-1,1-diphosphonoethane
1-Hydroxyethane-1,1,-diphosphonic acid
1-Hydroxyethane-1,1-bisphosphonic acid
1-Hydroxyethane-1,1-diphosphonate
1-Hydroxyethane-1,1-diphosphonic acid
1-Hydroxyethanediphosphonic acid
1-Hydroxyethylidene 1,1-diphosphonic acid
1-Hydroxyethylidene-1,1-biphosphonate
1-Hydroxyethylidene-1,1-bisphosphonate
1-Hydroxyethylidene-1,1-diphosphonic acid
1-Hydroxyethylidenediphosphonic acid
1-hydroxyethane 1,1-diphosphonic acid
1000SL
100511-44-2
103736-66-9
106908-76-3
129130-42-3
138360-84-6
14860-53-8 (tetra-potassium salt)
192526-55-9
2809-21-4
303177-33-5
51888-66-5
54342_ALDRICH
54342_FLUKA
66216-98-6
853028-38-3
85985-26-8
86159-18-4
AC1L1FMT
Acetodiphosphonic acid
Acide etidronique
Acide etidronique [INN-French]
Acido etidronico
Acido etidronico [INN-Spanish]
Acidum etidronicum
Acidum etidronicum [INN-Latin]
BPBio1_000997
BRN 1789291
BSPBio_000905
Bio-0708
C07736
CHEBI:170675
CHEBI:4907
CHEMBL871
CID3305
 
Cintichem Technetium 99m Hedspa
D02373
DB01077
Dequest 2010
Dequest 2015
Dequest Z 010
Didronel
Didronel IV
Diphosphonate (base)
EHDP
EINECS 220-552-8
Ethane-1-hydroxy-1,1-bisphosphonate
Ethane-1-hydroxy-1,1-bisphosphonic acid
Ethane-1-hydroxy-1,1-diphosphonate
Ethane-1-hydroxy-1,1-diphosphonic acid
Etidronate
Etidronate Disodium
Etidronic acid
Etidronic acid (USAN/INN)
Etidronic acid [USAN:INN:BAN]
Etidronic acid monohydrate
Etidronsaeure
Etidronsäure
Ferrofos 510
H0587
H6773_ALDRICH
H6773_SIGMA
HEDP
HSDB 5898
Hydroxyethane-1,1-diphosphonic acid
Hydroxyethanediphosphonic acid
I14-1271
Jsp005415
LS-106637
MLS002207267
MLS002695948
MPI Stannous Diphosphonate
MolPort-001-786-542
NCGC00159352-02
NSC 227995
NSC227995
Osteoscan
Oxyethylidenediphosphonic acid
Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester
Prestwick0_000863
Prestwick1_000863
Prestwick2_000863
Prestwick3_000863
RP 61
SMR000038750
SPBio_002826
STK721995
Turpinal SL
UNII-M2F465ROXU
acide étidronique
acidum etidronicum
ethane-1-hydroxy-1,1-bisphosphonic acid
etidronate
ácido etidrónico
2Risedronate SodiumPhase 2, Phase 398115436-72-1
3Bone Density Conservation AgentsPhase 2, Phase 33266
4DiphosphonatesPhase 2, Phase 3446
5calcium channel blockersPhase 2, Phase 31940
6Calcium, DietaryPhase 2, Phase 35525
7Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 3, Phase 2, Phase 112767
8HormonesPhase 3, Phase 2, Phase 113979
9Hormone AntagonistsPhase 3, Phase 2, Phase 112778
10
AlendronateapprovedPhase 2160121268-17-5, 66376-36-12088
Synonyms:
(4-Amino-1-hydroxybutylidene)bisphosphonic acid
(4-Amino-1-hydroxybutylidene)diphosphonic acid
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
(4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid)
(4-amino-1-hydroxybutylidene)bisphosphonic acid
121268-17-5 (mono-hydrochloride salt, trihydrate)
1yhm
4-Amino-1-hydroxybutane-1,1-diphosphonate
4-Amino-1-hydroxybutane-1,1-diphosphonic Acid
4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
4-amino-1-hydroxybutane-1,1-diphosphonic acid
66376-36-1
ABDP
AC1L1CW3
AKOS001015793
ALENDRONATE SODIUM
ALENDRONIC ACID
Acide Alendronique
Acide Alendronique [INN-French]
Acide alendronique
Acide alendronique [INN-French]
Acido Alendronico
Acido Alendronico [INN-Spanish]
Acido alendronico
Acido alendronico [INN-Spanish]
Acidum Alendronicum
Acidum Alendronicum [INN-Latin]
Acidum alendronicum
Acidum alendronicum [INN-Latin]
Adronat
 
Alendronate
Alendronate Sodium
Alendronate sodium hydrate
Alendronic acid
Alendronic acid (INN)
Alendronic acid [INN:BAN]
Alendros
Arendal
BIDD:GT0180
C07752
CHEBI:2567
CHEMBL870
CID2088
D07119
DB00630
Fosamax
Fosamax Plus D
HSCI1_000337
LS-106421
MK 217
MK-217
MolPort-000-421-410
NCGC00096054-01
NCGC00096054-03
NCGC00096054-04
Onclast
Oprea1_422906
Phosphonic acid, (4-amino-1-hydroxybutylidene)bis
SPECTRUM1505166
ST50036159
UNII-X1J18R4W8P
alendronate
bisphosphonate, 65
11
TestolactoneapprovedPhase 24968-93-413769
Synonyms:
(4AS,4br,10ar,10bs,12as)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-F]chromene-2,8(4bh)-dione
(4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bH)-dione
(4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3H-naphtho[2,1-f]chromene-2,8-dione
.DELTA.1-Dehydrotestolactone
.DELTA.1-Dehydrotestololactone
.DELTA.1-Testololactone
1 Dehydrotestolactone
1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic acid delta-lactone
1,2-Dehydrotestololactone
1,2-Didehydrotestololactone
1,2-didehydrotestololactone
1-Dehydrotestolactone
1-Dehydrotestololactone
1-dehydrotestololactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, .delta.-lactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, delta-lactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, delta-lactone (8CI)
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, lactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13.alpha.-hydroxy-3-oxo-, .delta.-lactone
13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid .delta.-lactone
13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone
17a-Oxa-D-homoandrosta-1,4-diene-3,17-dione
17alpha-Oxo-D-homo-1,4-androstadiene-3,17-dione
2H-Phenanthro[2,1-b]pyran-2,8(4bH)-dione, 3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-dimethyl-, lactone
3-oxo-13,17-secoandrosta-1,4-dieno-17,13alpha-lactone
968-93-4
AC1L22FS
Bristol Myers Squibb Brand of Testolactone
Bristol-Myers Squibb Brand of Testolactone
C02197
C19H24O3
CHEBI:9460
CHEMBL1571
CID13769
D-Homo-17A-oxaandrosta-1,4-diene-3,17-dione
D-Homo-17a-oxaandrosta-1,4-diene-3,17-dione
 
D00153
D013738
DB00894
Delta(1)-testololactone
Delta-1-testololactone
EINECS 213-534-6
Fludestrin
HSDB 3255
LMST02020084
LS-102968
MolPort-004-286-011
NCI60_001908
NSC 23759
NSC-12173
NSC23759
SQ 9538
SQ-9538
TESLAC (TN)
Teolit
Teslac
Teslak
Testolacton
Testolactona
Testolactona [INN-Spanish]
Testolactone
Testolactone (USP/INN)
Testolactone [USAN:INN]
Testolactonum
Testolactonum [INN-Latin]
Testolattone
Testolattone [DCIT]
Testolattone [Dcit]
UNII-6J9BLA949Q
ZINC04081771
delta(1)-Dehydrotestolactone
delta(1)-Testolactone
delta(1)-Testololactone
12
Anastrozoleapproved, investigationalPhase 2272120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
13
Fulvestrantapproved, investigationalPhase 2194129453-61-8104741, 17756771
Synonyms:
(7R,13S,17S)-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
(7R,8S,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl) nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
(7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol
129453-61-8
7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)estra-1,3,5(10)-triene-3,17-diol
7alpha-(9-((4,4,5,5,5,-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol
7alpha-(9-((4,4,5,5,5-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol
7alpha-[9[(4,4,5,5,5-Pentafluropentyl)sulfinyl]nonyl]-estra-1,3,5(10)-triene-3, 17 beta diol
AC-4693
AC1L2XEN
AstraZeneca brand of fulvestrant
BIDD:ER0348
BIDD:PXR0136
C070081
C32H47F5O3S
CCRIS 8741
CHEBI:404798
CHEMBL1358
CID104741
D01161
DB00947
Faslodex
Faslodex (TN)
 
Faslodex(ICI 182,780)
Faslodex, ICI 182780, Fulvestrant
Fulvestrant
Fulvestrant (JAN/USAN/INN)
Fulvestrant [USAN]
HMS2090N22
HSDB 7658
I06-1109
ICI 182,780
ICI 182,789
ICI-182780
Ici 182780
LS-64781
NCGC00164789-02
NSC719276
S1191_Selleck
UNII-22X328QOC4
ZD 182780
ZD-182780
ZD-9238
ZM 182780
ZM-182780
fulvestrant
nchembio.168-comp5
nchembio.76-comp5
nchembio775-comp4
14Estrogen AntagonistsPhase 2, Phase 11315
15Steroid Synthesis InhibitorsPhase 2, Phase 11718
16Aromatase InhibitorsPhase 2, Phase 1807
17EstrogensPhase 2, Phase 12470
18Antineoplastic Agents, HormonalPhase 25407
19Estrogen Receptor AntagonistsPhase 2186
20
Letrozoleapproved, investigationalPhase 1382112809-51-53902
Synonyms:
1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
112809-51-5
4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
AB00514009
AC-1193
AC1L1GYT
AKOS005145822
BIDD:GT0015
BIDD:PXR0130
BPBio1_001331
BRD-K88789588-001-03-2
BSPBio_001209
Bio-0057
C067431
C08163
C17H11N5
CAS-112809-51-5
CCRIS 8822
CGS 20267
CGS 20267, Femara, Piroxicam, Letrozole
CGS-20267
CHEBI:6413
CHEMBL1444
CID3902
CPD000466343
D00964
 
DB01006
FEM-345
Femara
Femara (TN)
Femera
HMS1571M11
HMS2051E08
HMS2089L22
HSDB 7461
I06-0022
LS-38788
Letoval
Letrozol
Letrozole
Letrozole (JAN/USP/INN)
Letrozole [USAN:INN]
MLS000759455
MLS001424038
MLS002584991
MolPort-003-848-373
NCGC00016973-01
NCGC00016973-02
NSC719345
Novartis Brand of Letrozole
Prestwick0_001025
Prestwick1_001025
Prestwick2_001025
Prestwick3_001025
S1235_Selleck
SAM001246649
SMR000466343
SPBio_003070
TL8000371
UNII-7LKK855W8I
ZINC03778874
letrozole
21
Histamineapproved103475614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
22
Histamine Phosphateapproved103351-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
23Neurotransmitter Agents17734

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of BoneUnknown statusNCT00445575Phase 2, Phase 3
2A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright SyndromeCompletedNCT00017927Phase 3
3TOCILIZUMAB IN FIBROUS DYSPLASIA OF BONEUnknown statusNCT01791842Phase 2
4Alendronate to Treat Polyostotic Fibrous Dysplasia and McCune-Albright SyndromeCompletedNCT00001728Phase 2
5Testolactone for the Treatment of Girls With LHRH Resistant Precocious PubertyCompletedNCT00001181Phase 2
6Arimidex in McCune Albright SyndromeCompletedNCT00055302Phase 2
7PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright SyndromeRecruitingNCT02743377Phase 1, Phase 2
8Faslodex in McCune Albright SyndromeActive, not recruitingNCT00278915Phase 2
9Effects of Letrozole on Precocious Puberty Due to McCune Albright SyndromeCompletedNCT00006174Phase 1
10Histamine Responsiveness in McCune-Albright SyndromeUnknown statusNCT00318097
11Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright SyndromeCompletedNCT00001973
12The Influence of Bisphosphonates in the Oral Cavity in ChildrenCompletedNCT00402064
13Bone Marrow Injection to Replace Diseased Bone in Polyostotic Fibrous Dysplasia and McCune-Albright SyndromeCompletedNCT00001851
14Natural History of Cherubism Observational StudyCompletedNCT01916772
15Interest of Serum Periostin Dosage in Patients With Bone Fibrous DysplasiaRecruitingNCT02868645
16Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and McCune-Albright SyndromeRecruitingNCT00001727
17Genetic and Functional Analysis of CherubismRecruitingNCT01630447

Search NIH Clinical Center for Osteitis Fibrosa


Cochrane evidence based reviews: osteitis fibrosa cystica

Genetic Tests for Osteitis Fibrosa

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Anatomical Context for Osteitis Fibrosa

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MalaCards organs/tissues related to Osteitis Fibrosa:

36
Bone, Bone marrow, Brain, Thyroid, T cells, Kidney, Skin

FMA organs/tissues related to Osteitis Fibrosa:

17
Bone

Publications for Osteitis Fibrosa

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Articles related to Osteitis Fibrosa:

(show top 50)    (show all 149)
idTitleAuthorsYear
1
Osteitis fibrosa cystica. (27238197)
2016
2
A Rare Case of Concomitant Maxilla and Mandible Brown Tumours, Papillary Thyroid Carcinoma, Parathyroid Adenoma, and Osteitis Fibrosa Cystica. (26881146)
2016
3
Impact of curative surgery on bone in a patient with osteitis fibrosa cystica of primary hyperparathyroidism. (27030464)
2016
4
Facial disfigurement due to osteitis fibrosa cystica or brown tumor from secondary hyperparathyroidism in patients on dialysis: A systematic review and an illustrative case report. (25828738)
2015
5
Osteitis fibrosa cystica in primary hyperparathyroidism. (26261355)
2015
6
Tumor suppressor gene mutation in a patient with a history of hyperparathyroidism-jaw tumor syndrome and healed generalized osteitis fibrosa cystica: a case report and genetic pathophysiology review. (25511968)
2015
7
Brown tumors: severe osteitis fibrosa cystica. (25939949)
2015
8
Radiographical appearance of osteitis fibrosa cystica in primary hyperparathyroidism before and after parathyroidectomy. (23365170)
2013
9
Osteitis fibrosa cystica mistaken for malignant disease. (23799171)
2013
10
Hyperparathyroidism-jaw tumour syndrome detected by aggressive generalized osteitis fibrosa cystica. (23858315)
2013
11
Successful treatment of osteitis fibrosa cystica from primary hyperparathyroidism. (23259108)
2012
12
Bisphosphonates can reduce bone hunger after parathyroidectomy in patients with primary hyperparathyroidism and osteitis fibrosa cystica. (21584419)
2011
13
A rare case of primary hyperparathyroidism and osteitis fibrosa cystica. (20919975)
2010
14
Visual vignette. Osteitis fibrosa cystica. (18753115)
2008
15
Fine needle aspiration diagnosis of osteitis fibrosa cystica (brown tumor of bone): a case report. (18702368)
2008
16
Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidism. (18635661)
2008
17
Osteitis fibrosa cystica and secondary hyperparathyroidism in multiple myeloma. (17062009)
2007
18
Oxyphilic cell adenoma of parathyroid resulting in primary hyperparathyroidism and osteitis fibrosa cystica--a case report. (17001919)
2006
19
Pathologic fracture of the distal femur in osteitis fibrosa cystica simulating metastatic disease. (15168133)
2004
20
Osteitis fibrosa cystica, coeliac disease and Turner syndrome. A case report. (15285529)
2004
21
Recovery pattern of patients with osteitis fibrosa cystica in primary hyperparathyroidism after successful parathyroidectomy. (12490858)
2002
22
Radiology quiz case 2: metastatic calcifications of the middle and external ear and osteitis fibrosa of the temporal bones as a result of secondary hyperparathyroidism. (11926927)
2002
23
Cytokine accumulation in osteitis fibrosa of renal osteodystrophy. (11743611)
2002
24
Effect of parathyroid adenoma resection on bone density in primary hyperparathyroidism and osteitis fibrosa cystica. (11688767)
2001
25
Tc99m-sestamibi uptake in osteitis fibrosa cystica simulating metastatic bone disease. (11701666)
2001
26
False positive 99mTc sestamibi scans in patients with osteitis fibrosa cystica and brown tumours. (11716445)
2001
27
Images in haematology. Osteitis fibrosa cystica generalisata with adult T-cell leukaemia: a case report. (11054056)
2000
28
22-Oxacalcitriol ameliorates high-turnover bone and marked osteitis fibrosa in rats with slowly progressive nephritis. (10594779)
1999
29
Osteitis fibrosa cystica generalizata with adult T-cell leukaemia: a case report. (10606900)
1999
30
Osteitis fibrosa: treatment trends. (9543904)
1998
31
NPS R-568 halts or reverses osteitis fibrosa in uremic rats. (9461105)
1998
32
Osteitis fibrosa cystica with renal parathyroid hormone resistance: a review of pseudohypoparathyroidism with insight into calcium homeostasis. (9637471)
1998
33
Marked improvement in bone mass after parathyroidectomy in osteitis fibrosa cystica. (9506717)
1998
34
Comment on marked improvement in bone mass after parathyroidectomy in osteitis fibrosa cystica. (9768702)
1998
35
Osteitis fibrosa cystica and chronic renal failure. (9158318)
1997
36
Spontaneous healing of osteitis fibrosa cystica in primary hyperparathyroidism. (9015472)
1996
37
Intravenous calcitriol can increase bone mass in hemodialysis patients with osteitis fibrosa. (7565429)
1995
38
Inhibition of 1,25(OH)2D production by hypercalcemia in osteitis fibrosa cystica: influence on parathyroid hormone secretion and hungry bone disease. (8274876)
1993
39
Osteitis fibrosa cystica simulating metastatic tumor. An almost-forgotten relationship. (8249919)
1993
40
Pseudohypoparathyroidism with osteitis fibrosa cystica: direct demonstration of skeletal responsiveness to parathyroid hormone in cells cultured from bone. (8427051)
1993
41
Paraplegia due to osteitis fibrosa secondary to primary hyperparathyroidism: report of a case. (8292854)
1993
42
Case management of the anemic patient: epoetin alfa--focus on osteitis fibrosa. (8285805)
1993
43
Osteitis fibrosa cystica (brown tumor) in a patient with renal transplantation. Report of a case with aspiration cytodiagnosis. (1636352)
1992
44
Current advances in the therapy of secondary hyperparathyroidism and osteitis fibrosa. (1813787)
1991
45
Osteitis fibrosa cystica (brown tumor) of the spine with cord compression: report of a case with needle aspiration biopsy findings. (2292220)
1990
46
Marked direct suppression of primary hyperparathyroidism with osteitis fibrosa cystica by intravenous administration of 1,25-dihydroxycholecalciferol. (2615719)
1989
47
Concomitant osteitis fibrosa cystica and ameloblastoma of the mandible. (2724257)
1989
48
Intravenous calcitriol in the treatment of refractory osteitis fibrosa of chronic renal failure. (2631697)
1989
49
Prevention of osteitis fibrosa, aluminium bone disease and soft-tissue calcification in dialysis patients: a long-term comparison of moderate doses of oral calcium +/- Mg(OH)2 vs Al(OH)3 +/- 1 alpha OH vitamin D3. (2517325)
1989
50
Calcitriol for osteitis fibrosa. (2594044)
1989

Variations for Osteitis Fibrosa

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Expression for genes affiliated with Osteitis Fibrosa

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Search GEO for disease gene expression data for Osteitis Fibrosa.

Pathways for genes affiliated with Osteitis Fibrosa

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GO Terms for genes affiliated with Osteitis Fibrosa

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Biological processes related to Osteitis Fibrosa according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of ossificationGO:004577810.3CALCA, PTH
2ossificationGO:000150310.2BGLAP, CASR
3positive regulation of cell proliferation in bone marrowGO:007186410.2IL6, PTH
4monocyte chemotaxisGO:000254810.2CALCA, IL6
5bone developmentGO:006034810.2BGLAP, GNAS
6response to mechanical stimulusGO:000961210.1BGLAP, IL6
7response to heatGO:000940810.1CALCA, IL6
8positive regulation of osteoblast differentiationGO:004566910.0GNAS, IL6
9agingGO:00075689.8BGLAP, CALCA, IL6
10cellular calcium ion homeostasisGO:00068749.8CALCA, CASR, PTH
11response to vitamin DGO:00332809.7BGLAP, PTH
12adenylate cyclase-activating G-protein coupled receptor signaling pathwayGO:00071899.7CALCA, GNAS, PTH
13response to nutrient levelsGO:00316679.5BGLAP, IL6, PTH
14response to drugGO:00424939.1BGLAP, GNAS, IL6, PTH

Sources for Osteitis Fibrosa

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet