MCID: OST006
MIFTS: 32

Osteoblastoma

Categories: Bone diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Osteoblastoma

Summaries for Osteoblastoma

MalaCards based summary : Osteoblastoma is related to osteoid osteoma and cervicitis. An important gene associated with Osteoblastoma is CTNNB1 (Catenin Beta 1). Affiliated tissues include bone, thyroid and pineal, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 72 Osteoblastoma is an uncommon osteoid tissue-forming primary neoplasm of the... more...

Related Diseases for Osteoblastoma

Graphical network of the top 20 diseases related to Osteoblastoma:



Diseases related to Osteoblastoma

Symptoms & Phenotypes for Osteoblastoma

GenomeRNAi Phenotypes related to Osteoblastoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-167 9.36 NELL1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.36 CTNNB1 NELL1 SPARC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-191 9.36 CTNNB1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-204 9.36 NELL1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.36 NELL1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.36 SPARC
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.36 NELL1 SPARC
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-86 9.36 NELL1

Drugs & Therapeutics for Osteoblastoma

Search Clinical Trials , NIH Clinical Center for Osteoblastoma

Genetic Tests for Osteoblastoma

Anatomical Context for Osteoblastoma

MalaCards organs/tissues related to Osteoblastoma:

38
Bone, Thyroid, Pineal, Breast, Spinal Cord, Bone Marrow

Publications for Osteoblastoma

Articles related to Osteoblastoma:

(show top 50) (show all 560)
# Title Authors Year
1
Pseudomalignant osteoblastoma of the odontoid process. ( 29380146 )
2018
2
Neoadjuvant denosumab for the treatment of a sacral osteoblastoma. ( 29356985 )
2018
3
A case of spinal osteoblastoma in the elderly: is it really a young patient's disease? ( 29421450 )
2018
4
A rare case of osteoblastoma from medieval Tuscany. ( 29304355 )
2018
5
Osteoblastoma Mimicking an Idiopathic Intracranial Hypertension Syndrome. ( 28553393 )
2017
6
Elevated I^-hCG associated with aggressive Osteoblastoma. ( 28396962 )
2017
7
Osteoblastoma of the hamate bone - a case report. ( 28905333 )
2017
8
Epithelioid osteoblastoma: A histopathological dilemma between juvenile ossifying fibroma and low-grade osteosarcoma. ( 28479709 )
2017
9
Spinal osteoid osteoma progressed to osteoblastoma with paraspinal soft tissue mass: a unique presentation. ( 27999873 )
2017
10
Suboccipital osteoblastoma: Microsurgical resection of a rare entity. ( 28458947 )
2017
11
Activation of the arachidonic acid metabolic pathway and induction of sleep disturbance by sacral osteoblastoma: A case report. ( 28781793 )
2017
12
Clinics in diagnostic imaging (174). L5 vertebral superior facet osteoblastoma (OB). ( 28210742 )
2017
13
Aggressive Osteoblastoma in the Maxilla: Unusual Lesion in the Craniofacial Skeleton. ( 28468168 )
2017
14
Percutaneous radiofrequency ablation for spinal osteoid osteoma and osteoblastoma. ( 28391383 )
2017
15
Preoperative Embolization and Complete Tumoral Resection of a Cervical Aggressive Epithelioid Osteoblastoma. ( 28710051 )
2017
16
Aggressive Osteoblastoma in the Maxilla: Unusual Lesion in the Craniofacial Skeleton. ( 28277479 )
2017
17
Breast osteoblastoma and recurrence after resection: Demonstration by color Doppler ultrasound. ( 28506022 )
2017
18
Osteoblastoma of the elbow: analysis of 13 patients and literature review. ( 28634923 )
2017
19
microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation. ( 28460435 )
2017
20
Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report. ( 27853880 )
2017
21
CT-guided radiofrequency ablation of spinal osteoblastoma: treatment and long-term follow-up. ( 28597707 )
2017
22
A rare case of osteoblastoma combined with severe scoliosis deformity, coronal and sagittal imbalance. ( 29258494 )
2017
23
Rare Aggressive Calvarial Osteoblastoma with Dural Invasion. ( 29204329 )
2017
24
Osteoblastoma of the thyroid cartilage. ( 27206395 )
2016
25
An Osteoblastoma of the Mandible: A Case Study. ( 29045089 )
2016
26
Malignant transformation of a high-grade osteoblastoma of the petrous apex with subcutaneous metastasis. ( 27304442 )
2016
27
Surgical management of an osteoblastoma involving the entire C2 vertebra and a review of literature. ( 26879919 )
2016
28
Epithelioid osteoblastoma of maxilla: A rare and aggressive variant of a benign neoplasm at an uncommon site. ( 27601840 )
2016
29
Osteoblastoma of the thoracic spine presenting with back pain. ( 26792200 )
2016
30
Osteoblastoma originating from frontoethmoidal sinus causing personality disorders and superior gaze palsy. ( 26755236 )
2016
31
Anterior Reconstruction of C2-C3 Bodies in a 6-Year-Old Patient with a Huge Osteoblastoma: A Novel Technique. ( 26835212 )
2016
32
Osteoblastoma of the temporal articular tubercle misdiagnosed asA a temporomandibular joint disorder. ( 28043747 )
2016
33
Agressive osteoblastoma in a seven-year-old girl's mandible: Treatment and six-year monitoring. ( 27518431 )
2016
34
Unusual presentation of osteoblastoma as vertebra plana - a case report and review of literature. ( 27664343 )
2016
35
Osteoblastoma of the maxillary sinus in a child presenting with exophthalmos. ( 26895762 )
2016
36
Surgical Management of Osteoblastoma of the Spine: Case Series and Review of the Literature. ( 27400109 )
2016
37
The effect of simple local resection on pain and scoliotic curve in patients with scoliosis secondary to osteoid osteoma and osteoblastoma in the spine. ( 27130390 )
2016
38
Osteoid osteoma of the temporal bone manifesting as first bite syndrome and a meta-analysis combined with osteoblastoma. ( 27106094 )
2016
39
Bilateral C-1 lateral mass reconstruction following radical resection of a giant osteoblastoma of the atlas: case report. ( 27834626 )
2016
40
Non Aggressive Mandibular Osteoblastoma- A Rare Maxillofacial Entity. ( 27190965 )
2016
41
Removal of osteoblastoma of the talar neck using standard anterior ankle Arthroscopyi19A case report. ( 27100951 )
2016
42
Dorsal spine osteoblastoma. ( 27057242 )
2016
43
Surgical resection of osteoid osteoma and osteoblastoma of the spine. ( 27832013 )
2016
44
Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report. ( 27981453 )
2016
45
Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma. ( 27324965 )
2016
46
Malignant transformation of aggressive osteoblastoma to ostesarcoma. ( 27499324 )
2016
47
Orbital Osteoblastoma: Technical Innovations in Resection and Reconstruction Using Virtual Surgery Simulation. ( 27516847 )
2016
48
Aggressive osteoblastoma of the temporal bone: an unusual cause of facial palsy. ( 26923829 )
2016
49
Clinical management of a challenging malignancy, osteoblastoma-like osteosarcoma: a report of four cases and a review of the literature. ( 27574436 )
2016
50
Intercostal neuralgia as a symptom of an osteoblastoma in thoracic spine. ( 26139654 )
2015

Variations for Osteoblastoma

Expression for Osteoblastoma

Search GEO for disease gene expression data for Osteoblastoma.

Pathways for Osteoblastoma

GO Terms for Osteoblastoma

Biological processes related to Osteoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lung development GO:0030324 9.37 CTNNB1 SPARC
2 canonical Wnt signaling pathway GO:0060070 9.32 CTNNB1 ZNRF3
3 positive regulation of osteoblast differentiation GO:0045669 9.26 CTNNB1 NELL1
4 cellular response to growth factor stimulus GO:0071363 9.16 CTNNB1 SPARC
5 limb development GO:0060173 8.96 CTNNB1 KREMEN1
6 Wnt signaling pathway GO:0016055 8.8 CTNNB1 KREMEN1 ZNRF3

Sources for Osteoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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