MCID: OST006
MIFTS: 31

Osteoblastoma malady

Categories: Bone diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Osteoblastoma

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Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 40MESH via Orphanet, 50Novoseek, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Summaries for Osteoblastoma

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Wikipedia:71 Osteoblastoma is an uncommon osteoid tissue-forming primary neoplasm of the bone. more...

MalaCards based summary: Osteoblastoma is related to cervicitis and periostitis. An important gene associated with Osteoblastoma is CTNNB1 (Catenin Beta 1), and among its related pathways is Signaling in Gap Junctions. Affiliated tissues include bone, thyroid and pineal, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and craniofacial.

Related Diseases for Osteoblastoma

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Graphical network of the top 20 diseases related to Osteoblastoma:



Diseases related to osteoblastoma

Symptoms & Phenotypes for Osteoblastoma

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GenomeRNAi Phenotypes related to Osteoblastoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-849.1CTNNB1, NELL1, SPARC

MGI Mouse Phenotypes related to Osteoblastoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.5CER1, CTNNB1, NELL1, SPARC

Drugs & Therapeutics for Osteoblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Osteoblastoma

Genetic Tests for Osteoblastoma

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Anatomical Context for Osteoblastoma

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MalaCards organs/tissues related to Osteoblastoma:

36
Bone, Thyroid, Pineal, Spinal cord, Bone marrow

Publications for Osteoblastoma

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Articles related to Osteoblastoma:

(show top 50)    (show all 539)
idTitleAuthorsYear
1
Spinal osteoid osteoma progressed to osteoblastoma with paraspinal soft tissue mass: a unique presentation. (27999873)
2017
2
Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report. (27853880)
2017
3
Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report. (27981453)
2016
4
Epithelioid osteoblastoma of maxilla: A rare and aggressive variant of a benign neoplasm at an uncommon site. (27601840)
2016
5
Removal of osteoblastoma of the talar neck using standard anterior ankle Arthroscopyi19A case report. (27100951)
2016
6
Non Aggressive Mandibular Osteoblastoma- A Rare Maxillofacial Entity. (27190965)
2016
7
Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma. (27324965)
2016
8
Aggressive osteoblastoma of the temporal bone: an unusual cause of facial palsy. (26923829)
2016
9
Orbital Osteoblastoma: Technical Innovations in Resection and Reconstruction Using Virtual Surgery Simulation. (27516847)
2016
10
Dorsal spine osteoblastoma. (27057242)
2016
11
Agressive osteoblastoma in a seven-year-old girl's mandible: Treatment and six-year monitoring. (27518431)
2016
12
Malignant transformation of aggressive osteoblastoma to ostesarcoma. (27499324)
2016
13
Osteoid osteoma of the temporal bone manifesting as first bite syndrome and a meta-analysis combined with osteoblastoma. (27106094)
2016
14
Osteoblastoma of the temporal articular tubercle misdiagnosed asA a temporomandibular joint disorder. (28043747)
2016
15
Osteoblastoma of the thyroid cartilage. (27206395)
2016
16
The effect of simple local resection on pain and scoliotic curve in patients with scoliosis secondary to osteoid osteoma and osteoblastoma in the spine. (27130390)
2016
17
Malignant transformation of a high-grade osteoblastoma of the petrous apex with subcutaneous metastasis. (27304442)
2016
18
Unusual presentation of osteoblastoma as vertebra plana - a case report and review of literature. (27664343)
2016
19
Surgical resection of osteoid osteoma and osteoblastoma of the spine. (27832013)
2016
20
Clinical management of a challenging malignancy, osteoblastoma-like osteosarcoma: a report of four cases and a review of the literature. (27574436)
2016
21
Bilateral C-1 lateral mass reconstruction following radical resection of a giant osteoblastoma of the atlas: case report. (27834626)
2016
22
Osteoblastoma of the thoracic spine presenting with back pain. (26792200)
2016
23
Surgical Management of Osteoblastoma of the Spine: Case Series and Review of the Literature. (27400109)
2016
24
Osteoblastoma of the maxillary sinus in a child presenting with exophthalmos. (26895762)
2016
25
Osteoblastoma originating from frontoethmoidal sinus causing personality disorders and superior gaze palsy. (26755236)
2016
26
Anterior Reconstruction of C2-C3 Bodies in a 6-Year-Old Patient with a Huge Osteoblastoma: A Novel Technique. (26835212)
2016
27
Surgical management of an osteoblastoma involving the entire C2 vertebra and a review of literature. (26879919)
2016
28
CT-Guided Percutaneous Cryoablation of an Aggressive Osteoblastoma: A Case Report. (26505944)
2015
29
Benign osteoblastoma of cervical spine. (26096485)
2015
30
Surgical treatment options for aggressive osteoblastoma in the mobile spine. (25847727)
2015
31
Intercostal neuralgia as a symptom of an osteoblastoma in thoracic spine. (26139654)
2015
32
Cutaneous epithelioid osteoblastoma. (25803726)
2015
33
Periosteal osteoblastoma of the pelvis: a rare case. (25648425)
2015
34
Sino-Orbital Osteoma With Osteoblastoma-Like Features. (25663319)
2015
35
Clinical characteristics and diagnostic imaging of cranial osteoblastoma. (25595957)
2015
36
A case report of osteoblastoma on the distal phalanx of the ring finger successfully treated with curettage and polymethylmethacrylate filling. (26072004)
2015
37
A rare case of osteoblastoma associated to aneurysmal bone cyst of the spine. Case report. (26204456)
2015
38
Epithelioid Multinodular Osteoblastoma of the Mandible: A Case Report and Review of Literature. (26507845)
2015
39
Osteoblastoma of the coracoid process: an unusual location. (26420699)
2015
40
Psammous desmo-osteoblastoma with concomitant aneurysmal bone cyst of mandible. (26389053)
2015
41
An unusual presentation of pediatric osteoblastoma in a patient with Klippel-Trenaunay-Weber syndrome: case report. (26030331)
2015
42
Destructive osteoblastoma with secondary aneurysmal bone cyst of cervical vertebra in an 11-year-old boy: case report. (24482719)
2014
43
Cervical osteoblastoma resection and posterior fusion. (24549390)
2014
44
Aggressive multilocular osteoblastoma in the mandible: a rare and difficult case to diagnose. (25517784)
2014
45
Unusual cause of back pain in a 13-year-old boy: a thoracic osteoblastoma. (24851081)
2014
46
I^-catenin is a valuable marker for differential diagnosis of osteoblastoma and osteosarcoma. (24746516)
2014
47
Extraosseous thoracic foraminal osteoblastoma: diagnostic dilemma and management with 3 year follow-up. (25346825)
2014
48
Clinical and morphological characteristics of osteoid osteoma and osteoblastoma: a retrospective single-center analysis of 204 patients. (25224389)
2014
49
A large multifocal aggressive osteoblastoma of mandible: an immunohistochemistry case study report. (25024840)
2014
50
Cervical osteoid osteoma progression to osteoblastoma. (24445325)
2014

Variations for Osteoblastoma

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Expression for genes affiliated with Osteoblastoma

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Search GEO for disease gene expression data for Osteoblastoma.

Pathways for genes affiliated with Osteoblastoma

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Pathways related to Osteoblastoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
8.9ADCY1, CTNNB1, TUBB2A

GO Terms for genes affiliated with Osteoblastoma

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Biological processes related to Osteoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cellular response to growth factor stimulusGO:007136310.3CTNNB1, SPARC
2negative regulation of angiogenesisGO:001652510.3CTNNB1, SPARC
3anterior/posterior axis specificationGO:000994810.2CER1, CTNNB1
4canonical Wnt signaling pathwayGO:006007010.2CTNNB1, ZNRF3
5negative regulation of Wnt signaling pathwayGO:00301789.9CER1, ZNRF3
6positive regulation of osteoblast differentiationGO:00456699.5CTNNB1, NELL1

Sources for Osteoblastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet