MCID: OST028
MIFTS: 48

Osteochondroma malady

Categories: Genetic diseases, Rare diseases, Bone diseases, Metabolic diseases, Fetal diseases

Aliases & Classifications for Osteochondroma

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Aliases & Descriptions for Osteochondroma:

Name: Osteochondroma 47 26 49
 
Cartilaginous Exostosis 67

Classifications:



Summaries for Osteochondroma

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Wikipedia:70 Osteochondromas or osteocartilaginous exostoses are the most common benign tumors of the bones. The... more...

MalaCards based summary: Osteochondroma, also known as cartilaginous exostosis, is related to trichorhinophalangeal syndrome, type ii and chondroblastoma. An important gene associated with Osteochondroma is EXT1 (Exostosin Glycosyltransferase 1), and among its related pathways are TP53 network and Vemurafenib Pathway, Pharmacodynamics. Affiliated tissues include bone, spinal cord and tongue, and related mouse phenotypes are neoplasm and integument.

Related Diseases for Osteochondroma

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Diseases in the Osteochondroma family:

Hereditary Multiple Osteochondromas

Diseases related to Osteochondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 130)
idRelated DiseaseScoreTop Affiliating Genes
1trichorhinophalangeal syndrome, type ii31.8EXT1, EXT2, FGF2, PTHLH
2chondroblastoma29.8S100B, VIM
3hereditary multiple osteochondromas12.4
4dysplasia epiphysealis hemimelica with chondromas and osteochondromas11.8
5metachondromatosis11.4
6carpotarsal osteochondromatosis11.0
7exostoses, multiple, type 110.9
8exostoses, multiple, type 210.9
9potocki-shaffer syndrome10.8
10pacman dysplasia10.7EXT1, EXT2
11heritable pulmonary arterial hypertension10.7EXT1, EXT2
12adenomyoma10.6EXT1, PTHLH
13flnb-related disorders10.6FGFR1, FGFR3
14plasmalogens synthesis deficiency isolated10.6FGFR1, FGFR3
15trigonocephaly 110.5FGFR1, FGFR3
16fryns macrocephaly10.5EXT1, EXT2, PTHLH
17neuropathy, ataxia, and retinitis pigmentosa10.5EXT1, EXT2, PTHLH
18localized chondrosarcoma10.5EXT1, PTHLH
19bladder cancer, somatic10.5FGFR1, FGFR3
20hypotonia10.4S100B, VIM
21anaplastic oligoastrocytoma10.4S100B, VIM
22exstrophy-epispadias complex10.4S100B, VIM
23thanatophoric dysplasia, type ii10.4FGF9, FGFR1, FGFR3
24absence of fingerprints congenital milia10.4S100B, VIM
25lymphangiosarcoma10.4S100B, VIM
26fraxf syndrome10.4S100B, VIM
27inflammatory mfh10.4PTHLH, S100B
28pulmonary venoocclusive disease10.3S100B, VIM
29beare-stevenson cutis gyrata syndrome10.3FGF2, FGFR1, FGFR3
30pediculus humanus capitis infestation10.3S100B, VIM
31solitary osseous plasmacytoma10.3BCL2, CDKN1A
32malignant cystic nephroma10.3S100B, VIM
33lumbar plexus neoplasm10.3S100B, VIM
34retroperitoneal germ cell neoplasm10.3EXT2, PTHLH, VIM
35sm-ahnmd10.3NES, VIM
36cervicitis10.3
37subependymal giant cell astrocytoma10.2S100B, VIM
38mollaret meningitis10.2BCL2, VIM
39intracystic papillary adenoma10.2NES, S100B
40anus leiomyosarcoma10.2PTHLH, S100B, VIM
41adenomyoma of uterine corpus10.2NES, S100B, VIM
42neutrophil immunodeficiency syndrome10.2NES, S100B, VIM
43novak syndrome10.1BCL2, S100B, VIM
44cervix endometrial stromal tumor10.1FGF2, S100B, VIM
45antley-bixler syndrome without genital anomalies or disordered steroidogenesis10.1FGF2, FGF9, FGFR1, FGFR3
46exostosis10.1
47bartholin's gland benign neoplasm10.1S100B, VIM
48chondrosarcoma10.1
49sclerosing liposarcoma10.1S100B, VIM
50malignant adenofibroma10.0S100B, VIM

Graphical network of the top 20 diseases related to Osteochondroma:



Diseases related to osteochondroma

Symptoms for Osteochondroma

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Drugs & Therapeutics for Osteochondroma

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Drugs for Osteochondroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Etoricoxibapproved, investigationalPhase 492202409-33-4123619
Synonyms:
202409-33-4
5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
5-Chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
5CH
AC1L3WZM
Algix
Arcoxia
C11718
C422649
CHEBI:106706
CHEBI:6339
CHEMBL416146
CID123619
D03710
DB01628
DB07166
ETORICOXIB
 
Etoricoxib
Etoricoxib (USAN/INN)
Etoricoxib [USAN:INN:BAN]
Etoricoxibe
Etoricoxibum
FT-0082494
HMS2090A05
L-791456
L001141
L791456
LS-181802
MK 0663
MK 663
MK-0663
MK-663
Merck Sharp & Dohme brand of etoricoxib
MolPort-003-847-339
NCGC00164578-01
Nucoxia
Tauxib
UNII-WRX4NFY03R
ZINC00579472
2
Tramadolapproved, investigationalPhase 423227203-92-533741
Synonyms:
(+)-(R,R)-trans-Tramadol
(+)-Tramadol
(+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol
(+)-trans-Tramadol free ba
(1R,2R)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexan-1-ol
(1R,2R)-2-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexanol
(1R,2R)-2-[(dimethylamino)methyl]-1-[3-(methyloxy)phenyl]cyclohexanol
27203-92-5
AC1L1Q6E
AC1Q59O2
AKOS005066335
Amanda
Amanda (TN)
BIDD:GT0075
C07153
CHEMBL1066
CID33741
Crispin
D08623
DB00193
EINECS 248-319-6
HMS2090D10
Jsp005295
LS-57115
 
LS-57116
MLS000333190
MolPort-002-507-778
NCGC00159343-02
Ralivia ER
Ralivia Flashtab
Ralivia flashtab
SMR000436547
STOCK4S-19075
Tradonal odis
Tramadol
Tramadol (INN)
Tramadol HCl
Tramadol HCl BP/EP
Tramadol [INN:BAN]
Tramadol hydrochloride
Tramadolum
Tramadolum [INN-Latin]
Tramal
Tramodol Hcl
Tridural
UNII-39J1LGJ30J
Ultram
Ultram ER
Zydol
tramadol
3Cyclooxygenase InhibitorsPhase 42778
4Peripheral Nervous System AgentsPhase 422776
5Cyclooxygenase 2 InhibitorsPhase 4616
6NarcoticsPhase 43486
7Central Nervous System DepressantsPhase 412806
8Analgesics, OpioidPhase 43091
9Analgesics, Non-NarcoticPhase 46260
10Anti-Inflammatory AgentsPhase 410355
11Anti-Inflammatory Agents, Non-SteroidalPhase 44295
12Antirheumatic AgentsPhase 410627
13AnalgesicsPhase 411287

Interventional clinical trials:

(show all 13)
idNameStatusNCT IDPhase
1A Randomized Trial to Evaluate the Effectiveness of Transferring the Flexor Hallucis Longus TendonUnknown statusNCT01341509Phase 4
2The Effect of Anti-inflammatory Analgesics on Pain Following Hallux Valgus SurgeryCompletedNCT00733421Phase 4
3Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon TransferCompletedNCT00950053Phase 4
4Autologous Stem Cells in Achilles TendinopathyRecruitingNCT02064062Phase 2
5The Health-Related Quality of Life in Patients With Hereditary Multiple ExostosesCompletedNCT00474448
6Cone-beam vs Multidetector Computed Tomography (CT) for Arthrography of the Wrist, Ankle, Elbow and KneeCompletedNCT01771393
7A Comparison of the Analgesic Efficacies of Ultrasound and Shock Wave Therapy in the Patients With Calcaneal SpurCompletedNCT01510249
8Effects of Myofascial Trigger Point Dry Cupping on Plantar Heel PainCompletedNCT02895698
9Effectiveness of Manual Therapy Combined With Standard Treatment in the Management of Plantar FasciitisCompletedNCT01439932
10The Fibrodysplasia Ossificans Progressiva (FOP) Connection RegistryRecruitingNCT02745158
11Evaluation of Effectiveness of Selected Physical and Kinesiotherapeutic Methods in Patients With Lower Calcaneal SpurRecruitingNCT02934100
12Gene Mutations and Orthopaedic Symptoms Correlation of Multiple Hereditary Exostoses: Multicentre ProjectSuspendedNCT00474331
13Establishing the Genetic Profile of Multiple Hereditary Exostoses (HME) in Families of BCTerminatedNCT00473850

Search NIH Clinical Center for Osteochondroma

Genetic Tests for Osteochondroma

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Genetic tests related to Osteochondroma:

id Genetic test Affiliating Genes
1 Osteochondroma26

Anatomical Context for Osteochondroma

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MalaCards organs/tissues related to Osteochondroma:

35
Bone, Spinal cord, Tongue, Appendix, Testes, Liver, Lymph node

Animal Models for Osteochondroma or affiliated genes

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MGI Mouse Phenotypes related to Osteochondroma:

40 (show all 23)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7BCL2, CDKN1A, E2F1, EXT1, FGF2, FGFR3
2MP:00107717.9BCL2, CDKN1A, E2F1, EXT1, FGF9, FGFR1
3MP:00053797.8BCL2, BMPR1B, CDKN1A, E2F1, FGF9, FGFR1
4MP:00053887.8BCL2, CDKN1A, E2F1, FGF9, FGFR3, PTHLH
5MP:00053697.7BCL2, CDKN1A, E2F1, FGF2, FGF9, FGFR1
6MP:00028737.7BMP2, BMPR1B, E2F1, EXT1, FGF9, FGFR1
7MP:00053717.5BMP2, BMPR1B, CDKN1A, EXT1, FGF9, FGFR1
8MP:00053827.1BCL2, BMP2, BMPR1B, CDKN1A, EXT1, FGF9
9MP:00053777.0BCL2, BMP2, CDKN1A, E2F1, EXT1, FGF2
10MP:00053807.0BMP2, BMPR1B, CDKN1A, E2F1, EXT1, EXT2
11MP:00053867.0BCL2, CDKN1A, E2F1, EXT1, FGF2, FGF9
12MP:00053916.5BCL2, BMPR1B, CDKN1A, E2F1, EXT1, FGF2
13MP:00053976.5BCL2, BMP2, CDKN1A, E2F1, FGF2, FGFR1
14MP:00053816.4BCL2, BMP2, CDKN1A, E2F1, EXT1, FGF9
15MP:00053906.3BMP2, BMPR1B, CDKN1A, E2F1, EXT1, EXT2
16MP:00053786.3BCL2, BMP2, BMPR1B, CDKN1A, E2F1, EXT1
17MP:00053856.2BCL2, BMP2, CDKN1A, E2F1, FGF2, FGF9
18MP:00053896.0BCL2, BMP2, BMPR1B, CDKN1A, E2F1, FGF2
19MP:00053765.7BCL2, BMP2, CDKN1A, E2F1, FGF2, FGF9
20MP:00036315.7BCL2, BMP2, BMPR1B, CDKN1A, E2F1, EXT1
21MP:00053845.7BCL2, BMP2, BMPR1B, CDKN1A, E2F1, EXT1
22MP:00107685.3BCL2, BMP2, BMPR1B, CDKN1A, E2F1, EXT1

Publications for Osteochondroma

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Articles related to Osteochondroma:

(show top 50)    (show all 695)
idTitleAuthorsYear
1
Pediatric Trigger Finger due to Osteochondroma: A Report of Two Cases. (28082852)
2017
2
Coracoid-like osteochondroma and painful giant thoracic bursitis. (26677990)
2016
3
Large solitary osteochondroma of the thoracic spine: Case report and review of the literature. (27274405)
2016
4
Subacromial osteochondroma: A rare cause of impingement syndrome. (25528042)
2015
5
Osteochondroma in long-term survivors of high-risk neuroblastoma. (25728463)
2015
6
Low condylectomy and orthognathic surgery to treat mandibular condylar osteochondroma: a retrospective review of 37 cases. (24997022)
2014
7
Osteochondroma of the palate: An interesting and an unusual case presentation. (25328318)
2014
8
Osteochondroma of coronoid process: a rare etiology of jacob disease. (25383153)
2014
9
Letter regarding "Effect of osteochondroma location on forearm deformity in patients with multiple hereditary osteochondromatosis". (23790427)
2013
10
Management of forearm deformities with ulnar shortening more than 15 mm caused by hereditary multiple osteochondromas. (23412166)
2013
11
Osteochondroma of mandibular condyle: A clinic-radiographic correlation. (24082753)
2013
12
Exome sequencing and functional analysis identifies a novel mutation in EXT1 gene that causes multiple osteochondromas. (24009674)
2013
13
Multiple osteochondromas following irradiation-containing conditioning in severe combined immunodeficiency. (23384194)
2013
14
Osteochondroma as a cause of scapular winging in an adolescent: a case report and review of the literature. (23971723)
2013
15
Giant costal osteochondroma in a man with multiple exostoses. (23910108)
2013
16
Mutation screening for the EXT1 and EXT2 genes in Chinese patients with multiple osteochondromas. (24120389)
2013
17
Tibial osteochondroma inducing popliteal artery compression. (24360241)
2013
18
Osteochondroma of the temporomandibular joint: report of 2 cases emphasizing the importance of personalizing the surgical treatment. (22669156)
2012
19
Malignant degeneration of a lumbar osteochondroma into a chondrosarcoma which mimicked a large retropertioneal mass. (22526879)
2012
20
3-D printout of a DICOM file to aid surgical planning in a 6 year old patient with a large scapular osteochondroma complicating congenital diaphyseal aclasia. (22690278)
2012
21
Solitary osteochondroma of the atlas causing spinal cord compression: a case report and literature review. (22744262)
2012
22
A synovial osteochondroma replacing the anterior cruciate ligament at the intercondylar notch. (21323282)
2011
23
Growth plate regulation and osteochondroma formation: insights from tracing proteoglycans in zebrafish models and human cartilage. (21506131)
2011
24
Spinal cord compression secondary to a thoracic vertebral osteochondroma. (21599443)
2011
25
Popliteal artery thrombosis secondary to a tibial osteochondroma. (21638255)
2011
26
Spinal cord compression due to C4 vertebral arch osteochondroma. (21094109)
2011
27
Scapular osteochondroma treated with arthroscopic excision using prone positioning. (20396684)
2010
28
Cervical spine osteochondroma: rare presentation of a common lesion. (21109061)
2010
29
Osteochondroma of the convexity: pathologic-neuroimaging correlates of a lesion that mimics high-grade meningioma. (20012156)
2010
30
Resected osteochondroma of the rib in an elderly patient. (21069500)
2010
31
Solitary synovial osteochondroma. (20227014)
2010
32
Rapidly developed huge bursitis associated with scapular osteochondroma of the multiple exostosis: a case report. (18682954)
2009
33
Dedifferentiated chondrosarcoma arising in a solitary osteochondroma with leiomyosarcomatous component: a case report. (18196252)
2008
34
Giant osteochondroma of the posterior cavity of the knee. (19226081)
2008
35
Discomfort during sexual intercourse secondary to osteochondroma: a report of two cases. (17588798)
2007
36
Para-articular osteochondroma of the knee. (17681220)
2007
37
An optimized DHPLC protocol for molecular testing of the EXT1 and EXT2 genes in hereditary multiple osteochondromas. (16283885)
2005
38
Subungual osteochondroma: clinical and radiologic features and treatment. (15209794)
2004
39
Unusual osteochondroma of the medial part of the clavicle causing subclavian vein thrombosis and brachial plexopathy. A case report. (15590864)
2004
40
A case report of osteochondroma of the frontotemporosphenoidal suture. (15149164)
2004
41
Arterial compromise caused by lower limb osteochondroma. (12799727)
2003
42
Spinal osteochondroma presenting as atypical spinal curvature: a case report. (12838114)
2003
43
Two cases of osteochondroma recurrence after surgical resection. (11198832)
2001
44
Solitary osteochondroma of the lower cervical spine. (11300298)
2001
45
Osteochondroma of the C5 lamina with cord compression: case report and review of the literature. (10806510)
2000
46
Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma. (11140704)
2000
47
Osteochondroma of the tracheal wall in a Fischer's lovebird (Agapornis fischeri, Reichenow 1887). (10216774)
1999
48
Dysplasia epiphysealis hemimelica. Upper limb involvement with associated osteochondroma. (7924021)
1994
49
Cervical osteochondroma (C2 level) with vertebral artery occlusion and second cervical nerve root irritation. (2718087)
1989
50
Osteochondroma with thoracic cord compression in hereditary multiple exostoses: a case report. (312508)
1979

Variations for Osteochondroma

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Expression for genes affiliated with Osteochondroma

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Search GEO for disease gene expression data for Osteochondroma.

Pathways for genes affiliated with Osteochondroma

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Pathways related to Osteochondroma according to GeneCards Suite gene sharing:

(show all 36)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7BCL2, CDKN1A
29.6FGF2, FGFR1, FGFR3
39.6FGF2, FGFR1, FGFR3
4
Show member pathways
9.6FGF2, FGF9, FGFR1
5
Show member pathways
9.4FGF2, FGF9, FGFR1, FGFR3
6
Show member pathways
9.4FGF2, FGF9, FGFR1, FGFR3
7
Show member pathways
9.4FGF2, FGF9, FGFR1, FGFR3
8
Show member pathways
9.4FGF2, FGF9, FGFR1, FGFR3
99.4FGF2, FGF9, FGFR1, FGFR3
109.3FGF2, FGFR1, TGFB2
11
Show member pathways
9.2BCL2, BMPR1B, FGFR1, FGFR3
129.2CDKN1A, E2F1, FGFR3
13
Show member pathways
9.1FGF2, FGFR1, FGFR3, TGFB2
148.9CDKN1A, FGF2, FGFR1, TGFB2
15
Show member pathways
8.9CDKN1A, E2F1, FGFR1, FGFR3
168.9FGF2, FGFR1, FGFR3, PTHLH, TGFB2
178.8FGF2, FGF9, FGFR1, FGFR3, TGFB2
188.8BMP2, FGF2, TGFB2
198.6BCL2, CDKN1A, FGF2, FGF9, FGFR1, FGFR3
208.5BCL2, CDKN1A, E2F1, FGF2, FGFR1
218.4BMP2, BMPR1B, FGF2, FGFR1, FGFR3
22
Show member pathways
8.3BMP2, FGF2, FGFR1, FGFR3, TGFB2
238.3BMP2, FGF2, FGFR1, FGFR3, TGFB2
248.3BCL2, BMP2, CDKN1A, E2F1
25
Show member pathways
8.2BCL2, CDKN1A, E2F1, FGF2, FGF9, FGFR1
267.9BCL2, CDKN1A, E2F1, FGFR3, TGFB2, VIM
27
Show member pathways
7.8BMP2, BMPR1B, E2F1, FGF2, TGFB2
287.8BMP2, FGF2, FGFR1, FGFR3, NES, S100B
297.8BCL2, BMP2, CDKN1A, E2F1, TGFB2
30
Show member pathways
7.7BCL2, BMP2, FGF2, FGF9, FGFR1, FGFR3
31
Show member pathways
7.6BCL2, BMP2, BMPR1B, FGF2, FGFR1, FGFR3
32
Show member pathways
7.5BCL2, BMP2, CDKN1A, FGF2, FGFR1, FGFR3
33
Show member pathways
7.2BCL2, BMP2, BMPR1B, CDKN1A, FGF2, FGFR1
346.6BCL2, BMP2, CDKN1A, E2F1, FGF2, FGF9
35
Show member pathways
6.6BCL2, BMP2, CDKN1A, E2F1, FGF2, FGF9
36
Show member pathways
6.1BCL2, BMP2, BMPR1B, CDKN1A, E2F1, FGF2

GO Terms for genes affiliated with Osteochondroma

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Cellular components related to Osteochondroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.5BMP2, FGF2, FGF9, FGFR1, FGFR3, PTHLH

Biological processes related to Osteochondroma according to GeneCards Suite gene sharing:

(show all 48)
idNameGO IDScoreTop Affiliating Genes
1cellular polysaccharide biosynthetic processGO:003369210.8EXT1, EXT2
2heparan sulfate proteoglycan biosynthetic processGO:001501210.7EXT1, EXT2
3positive regulation of endothelial cell chemotaxis to fibroblast growth factorGO:200054610.6FGF2, FGFR1
4positive regulation of phospholipase C activityGO:001086310.6FGF2, FGFR1
5heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic processGO:001501410.6EXT1, EXT2
6organ inductionGO:000175910.5FGF2, FGFR1
7positive regulation of phospholipase activityGO:001051810.5FGFR1, FGFR3
8salivary gland morphogenesisGO:000743510.3FGFR1, TGFB2
9positive regulation of cardiac muscle cell proliferationGO:006004510.2FGF2, FGF9, FGFR1
10embryonic digestive tract developmentGO:004856610.2FGF9, TGFB2
11generation of neuronsGO:004869910.2FGFR1, TGFB2
12lung-associated mesenchyme developmentGO:006048410.1FGF9, FGFR1
13ossificationGO:000150310.1BCL2, EXT1, EXT2
14phosphatidylinositol-3-phosphate biosynthetic processGO:003609210.0FGF2, FGF9, FGFR1, FGFR3
15lung developmentGO:003032410.0FGF2, FGF9, FGFR1
16mesenchymal cell differentiationGO:004876210.0BMP2, FGFR1
17thyroid-stimulating hormone-secreting cell differentiationGO:006012910.0BMP2, FGF2
18corticotropin hormone secreting cell differentiationGO:006012810.0BMP2, FGF2
19response to glucocorticoidGO:005138410.0BCL2, CDKN1A, S100B
20phosphatidylinositol phosphorylationGO:004685410.0FGF2, FGF9, FGFR1, FGFR3
21regulation of phosphatidylinositol 3-kinase signalingGO:001406610.0FGF2, FGF9, FGFR1, FGFR3
22positive regulation of cell divisionGO:005178110.0FGF2, FGF9, TGFB2
23phosphatidylinositol-mediated signalingGO:00480159.9FGF2, FGF9, FGFR1, FGFR3
24fibroblast growth factor receptor signaling pathwayGO:00085439.9FGF2, FGF9, FGFR1, FGFR3
25eye developmentGO:00016549.9BMPR1B, FGF9, TGFB2
26peptidyl-tyrosine phosphorylationGO:00181089.8FGF2, FGF9, FGFR1, FGFR3
27endocardial cushion morphogenesisGO:00032039.8BMP2, TGFB2
28positive regulation of cartilage developmentGO:00610369.8BMP2, BMPR1B
29pathway-restricted SMAD protein phosphorylationGO:00603899.8BMP2, TGFB2
30cardiac epithelial to mesenchymal transitionGO:00603179.8BMP2, TGFB2
31positive regulation of ossificationGO:00457789.8BMP2, TGFB2
32atrioventricular valve morphogenesisGO:00031819.7BMP2, TGFB2
33MAPK cascadeGO:00001659.6FGF2, FGF9, FGFR1, FGFR3
34positive regulation of cell differentiationGO:00455979.5BMP2, BMPR1B, FGF2
35positive regulation of osteoblast differentiationGO:00456699.4BMP2, BMPR1B, FGF2
36angiogenesisGO:00015259.4FGF2, FGF9, FGFR1, TGFB2
37branching involved in ureteric bud morphogenesisGO:00016589.4BCL2, BMP2, FGF2
38cellular response to hypoxiaGO:00714569.3BCL2, E2F1, S100B
39SMAD protein signal transductionGO:00603959.3BMP2, TGFB2, VIM
40regulation of cell cycleGO:00517269.1BCL2, CDKN1A, E2F1, FGF2
41chondrocyte differentiationGO:00020629.0BMP2, BMPR1B, FGF9, FGFR1, FGFR3
42cell-cell signalingGO:00072678.8BMP2, FGF9, FGFR3, PTHLH, TGFB2
43negative regulation of gene expressionGO:00106298.8BMP2, CDKN1A, FGFR1, TGFB2
44positive regulation of MAPK cascadeGO:00434108.7BMP2, DUSP19, FGF9, FGFR1, FGFR3
45skeletal system developmentGO:00015018.1BMP2, BMPR1B, EXT1, FGFR1, FGFR3, PTHLH
46positive regulation of cell proliferationGO:00082848.0BCL2, FGF2, FGF9, FGFR1, FGFR3, PTHLH
47negative regulation of cell proliferationGO:00082857.5BCL2, BMP2, CDKN1A, FGF2, PTHLH, TGFB2
48positive regulation of gene expressionGO:00106287.4BMP2, E2F1, FGF2, FGF9, TGFB2, VIM

Molecular functions related to Osteochondroma according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1heparan sulfate N-acetylglucosaminyltransferase activityGO:004232810.8EXT1, EXT2
2N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activityGO:005050910.8EXT1, EXT2
3glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activityGO:005050810.8EXT1, EXT2
4acetylglucosaminyltransferase activityGO:000837510.7EXT1, EXT2
5fibroblast growth factor-activated receptor activityGO:000500710.7FGFR1, FGFR3
61-phosphatidylinositol-3-kinase activityGO:001630310.0FGF2, FGF9, FGFR1, FGFR3
7phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:00469349.9FGF2, FGF9, FGFR1, FGFR3
8protein tyrosine kinase activityGO:00047139.8FGF2, FGF9, FGFR1, FGFR3
9Ras guanyl-nucleotide exchange factor activityGO:00050889.6FGF2, FGF9, FGFR1, FGFR3
10glycoprotein bindingGO:00019489.6BMPR1B, FGFR1, VIM
11growth factor activityGO:00080839.0BMP2, FGF2, FGF9, TGFB2
12protein homodimerization activityGO:00428038.6BCL2, EXT1, EXT2, FGFR1, S100B, TGFB2
13protein heterodimerization activityGO:00469828.1BCL2, BMP2, EXT1, EXT2, TGFB2

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
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39MESH via Orphanet
40MGI
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45NDF-RT
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52OMIM via Orphanet
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57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet