MCID: OST016
MIFTS: 47

Osteochondrosis malady

Rare diseases, Bone diseases categories

Aliases & Classifications for Osteochondrosis

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Aliases & Descriptions for Osteochondrosis:

Name: Osteochondrosis 32 10 45 12 65
Osteochondritis Juvenilis 10 65
Juvenile Osteochondrosis of Tibial Tubercle 65
Osteochondrosis Not Specified As Adult 10
Juvenile, of Unspecified Site 10
 
Epiphyseal Necrosis, Nos 10
Osteochondrosis Nos 10
Osteochondritis Nos 10
Apophysitis Nos 10
Epiphysitis Nos 10


Classifications:



External Ids:

Disease Ontology10 DOID:8125
NCIt42 C34879
MeSH36 D055034

Summaries for Osteochondrosis

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Disease Ontology:10 An ischemic bone disease that results in necrosis followed by regrowth in children and teens located in bone.

MalaCards based summary: Osteochondrosis, also known as osteochondritis juvenilis, is related to osteochondritis dissecans and osteoporosis. An important gene associated with Osteochondrosis is IGF1 (Insulin-Like Growth Factor 1 (Somatomedin C)), and among its related pathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and EGFR Transactivation by Gastrin. Affiliated tissues include bone, bone and testes, and related mouse phenotypes are adipose tissue and renal/urinary system.

Wikipedia:68 Osteochondrosis is a family of orthopedic diseases of the joint that occur in children and adolescents... more...

Related Diseases for Osteochondrosis

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Diseases related to Osteochondrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 140)
idRelated DiseaseScoreTop Affiliating Genes
1osteochondritis dissecans30.4ACAN, COL2A1, TGFB1
2osteoporosis29.9CD36, IGF1, NR3C1, TGFB1
3achondrogenesis, type ii or hypochondrogenesis29.7ACAN, CD36, COL2A1
4legg-calve-perthes disease10.4
5blount's disease10.4
6osgood-schlatter's disease10.4
7scheuermann's disease10.3
8kohler's disease10.3
9cervicitis10.3
10shigellosis10.3IGF1, IGF2
11endometrial stromal nodule10.3IGF1, IGF2
12juxtacortical chondrosarcoma10.3IGF1, IGF2
13laron dwarfism10.3IGF1, IGF2
14osteoarthritis10.2
15fibromatosis, gingival, 110.2CD36, TGFB1
16hyperinsulinism10.2IGF1, IGF2
17epileptic encephalopathy, early infantile, 110.2COL2A1, IGF1
18hemiplegia10.2IGF1, IGF2
19chronic ulcer of skin10.2CD36, TGFB1
20keratoconus10.2CD36, TGFB1
21fatal infantile encephalomyopathy10.2CD36, IGF1, IGF2
22fetal methimazole syndrome10.2IGF1, IGF2
23familial scheuermann disease10.2
24panner disease10.2
25sinding-larsen-johansson disease10.2
26lung cancer susceptibility 210.2CD36, IGF1, IGF2
27osteogenesis imperfecta congenita microcephaly and cataracts10.2CD36, TGFB1
28hodgkin's lymphoma, lymphocytic-histiocytic predominance10.1IGF1, NR3C1, TGFB1
29small cell cancer of the lung, somatic10.1IGF1, IGF2, TGFB1
30esophagus leiomyosarcoma10.1IGF2, IHH
31breast mucinous cystadenocarcinoma10.1IGF1, IGF2
32small intestine cancer10.1IGF2, IHH
33ocular melanoma10.1CD36, TGFB1
34thanatophoric dysplasia, type i10.1
35mucopolysaccharidosis is10.1
36sialidosis, type i10.1
37insulin-like growth factor i10.1
38spondylosis10.1
39metaphyseal dysplasia10.1
40freiberg's disease10.1
41upington disease10.1
42sapho syndrome10.1CD36, COL2A1, IGF1
43odontoma10.0ACAN, CD36
44leber congenital amaurosis 310.0ACAN, COL2A1
45cataract10.0ACAN, COL2A1
46hyperandrogenism9.9ACAN, COL2A1
47schwartz-jampel syndrome, type 19.9
48fucosidosis9.9
49pycnodysostosis9.9
50mandibuloacral dysplasia9.9

Graphical network of the top 20 diseases related to Osteochondrosis:



Diseases related to osteochondrosis

Symptoms for Osteochondrosis

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Drugs & Therapeutics for Osteochondrosis

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Drugs for Osteochondrosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Fibrin Tissue AdhesivePhase 2, Phase 3132
2
LidocaineapprovedPhase 1, Phase 2991137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
Bikini Zone Medicated Creme
Bio-0767
Bio-scriptives Lidum
Bio-scriptives Lidum Hemorroidal (anorectal)
Bio-scriptives Lidum Topical Analgesic
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Comfortcaine
Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
Derma Numb
DermaFlex
Desert Harvest Releveum
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Dr. Numb
Dr. Richs Numbing
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gigi Anesthetic Numbing
Gravocain
H-releve Hemorrhoidal
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
Hawaiian Tropic
Hush Anesthetic
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
LS-805
Lanabiotic
 
Laryng-o-jet
Leostesin
Lida-Mantle
Lidall
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine 4% Cream
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Hydrochloride
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocaine hydrochloride
Lidocainum
Lidocainum [INN-Latin]
Lidocare Mist
Lidocaton
Lidocream 4
Lidocream 5
Lidoderm
Lidoderm 5
Lidoject-1
Lidoject-2
Lifestyles Epic Male Genital Desensitizer
Lignocaine
Lignocainum
Lingocaine
Lmx4
Lmx5
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
Numb Nuts
Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
Simply Numb Endure
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocaine-mpf
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zcaine Fast Acting Anesthetic
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
3Calcium, Dietary3529
4AstragalusNutraceutical43

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral DefectsRecruitingNCT02423629Phase 4
2Comparison of Autologous Chondrocyte Implantation Versus Mosaicoplasty: a Randomized TrialCompletedNCT00560664Phase 3
3The Use of Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Articular Cartilage DefectsRecruitingNCT00891501Phase 2, Phase 3
4Comparison of Microfracture Treatment and CARTIPATCH® Chondrocyte Graft Treatment in Femoral Condyle LesionsTerminatedNCT00945399Phase 3
5Effectiveness of Dextrose Injection for Osgood-Schlatter DiseaseCompletedNCT01300754Phase 1, Phase 2
6Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the KneeRecruitingNCT01754298
7Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee:RecruitingNCT02397278
8Talar Avascular Necrosis: Surgical Angiogenesis vs. Core DecompressionRecruitingNCT02289976
9Clinical Assessment of the Missouri Osteochondral Allograft Preservation System - MOPSRecruitingNCT02503228
10Osteochondritis Dissecans of the KneeEnrolling by invitationNCT01455987
11Prospective Study of Scheuermann's KyphosisEnrolling by invitationNCT00738309
12Comparison of Standard Fusion With "Topping Off"-System in Lumbar SpineNot yet recruitingNCT01224379
13Cytokine Profiles in SpondylodiscitisNot yet recruitingNCT02554227
14A Prospective, Post-marketing Registry on the Use of ChondroMimetic for the Repair of Osteochondral DefectsTerminatedNCT01209390
15Estimation of the Long Term Effectiveness of Routine Use of Cardiac Shock Wave TherapyWithdrawnNCT01631409
16Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the KneeWithdrawnNCT02308358

Search NIH Clinical Center for Osteochondrosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Osteochondrosis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Osteochondrosis:
Carticel
Embryonic/Adult Cultured Cells Related to Osteochondrosis:
Chondrocytes (Carticel, PMIDs: 17515233, 17590152, 16510814

Genetic Tests for Osteochondrosis

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Anatomical Context for Osteochondrosis

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MalaCards organs/tissues related to Osteochondrosis:

33
Bone, Testes

FMA organs/tissues related to Osteochondrosis:

16
Bone

Animal Models for Osteochondrosis or affiliated genes

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MGI Mouse Phenotypes related to Osteochondrosis:

38 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.4CD36, COL2A1, IGF1, NR3C1, TGFB1
2MP:00053679.0CD36, COL2A1, IGF1, IGF2, NR3C1, TGFB1
3MP:00053798.5CD36, IGF1, IGF2, IHH, NR3C1, TGFB1
4MP:00053918.5CD36, COL2A1, IGF2, IHH, KLHDC2, TGFB1
5MP:00053718.5ACAN, COL2A1, IGF1, IGF2, IHH, MMP16
6MP:00053828.4ACAN, COL2A1, IGF2, IHH, MMP16, TGFB1
7MP:00053708.4ACAN, CD36, COL2A1, IGF2, NR3C1, TGFB1
8MP:00053888.2ACAN, COL2A1, IGF1, IGF2, IHH, NR3C1
9MP:00107718.2IGF1, IGF2, NR3C1, OSM, TGFB1, XIRP2
10MP:00053697.9ACAN, CD36, IGF1, IGF2, IHH, NR3C1
11MP:00053907.9ACAN, CD36, COL2A1, IGF1, IGF2, IHH
12MP:00053817.7ACAN, CD36, COL2A1, IGF2, IHH, MMP16
13MP:00053877.4ACAN, CD36, COL2A1, IGF1, IGF2, KLHDC2
14MP:00053857.2ACAN, CD36, COL2A1, IGF1, IGF2, IHH
15MP:00107686.9ACAN, CD36, COL2A1, IGF1, IGF2, IHH
16MP:00036316.8ACAN, CD36, COL2A1, IGF1, IGF2, IHH
17MP:00053866.7ACAN, CD36, COL2A1, IGF2, KLHDC2, NR3C1
18MP:00053786.4ACAN, CD36, COL2A1, IGF1, IGF2, IHH

Publications for Osteochondrosis

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Articles related to Osteochondrosis:

(show top 50)    (show all 390)
idTitleAuthorsYear
1
Omics technologies provide new insights into the molecular physiopathology of equine osteochondrosis. (25359417)
2014
2
Gene expression profiling of articular cartilage reveals functional pathways and networks of candidate genes for osteochondrosis in pigs. (23922127)
2013
3
Histological confirmation and biological significance of cartilage canals demonstrated using high field MRI in swine at predilection sites of osteochondrosis. (23939946)
2013
4
Effects of 25-hydroxy-cholecalciferol on the development of osteochondrosis in swine. (23590509)
2013
5
Outcome after arthroscopic treatment of lateral femoral trochlear ridge osteochondrosis in sport horses. A retrospective study of 37 horses. (23238225)
2013
6
Further evidence for better prevention of equine osteochondrosis. (23335686)
2013
7
Associations between osteochondrosis and conformation and locomotive characteristics in pigs. (22871924)
2012
8
Van neck disease: osteochondrosis of the ischiopubic synchondrosis. (21654459)
2011
9
Gene expression profiling from leukocytes of horses affected by osteochondrosis. (20108324)
2010
10
Sacral osteochondrosis in two German Shepherd Dogs. (19489784)
2009
11
Bilateral osteochondrosis of the superior pole of the patellae in association with bilateral osteochondritis dissecans of the lateral femoral condyle. (18325370)
2008
12
Autogenous osteochondral grafting for treatment of stifle osteochondrosis in dogs. (18564254)
2008
13
The use of fresh allografts in osteochondrosis dissecans of the lateral femoral condyle. (16953349)
2006
14
Osteochondrosis associated with copper deficiency in a red deer herd in Norway. (15581144)
2004
15
Expression of bone morphogenetic protein-6 and -2 and a bone morphogenetic protein antagonist in horses with naturally acquired osteochondrosis. (14719712)
2004
16
Osteochondrosis of the occipital condyles and atlanto-occipital dysplasia in a Belgian horse. (14703085)
2003
17
Nutrition and osteochondrosis. (9463862)
1998
18
Osteochondrosis of the femur. (9463860)
1998
19
Radiologic case study. Tibia vara (osteochondrosis deformans tibiae). (8936537)
1996
20
Osteochondrosis in a pedigree Suffolk ram. (8650917)
1996
21
Characterisation of articular and growth plate cartilage collagens in porcine osteochondrosis. (8175922)
1994
22
Comparison of the diagnostic accuracy of positive-contrast arthrography and arthrotomy in evaluation of osteochondrosis lesions in the scapulohumeral joint in dogs. (8407466)
1993
23
Economic relevance, diagnosis, and countermeasures for degenerative joint disease (osteoarthrosis) and dyschondroplasia (osteochondrosis) in pigs. (2200764)
1990
24
Atypical osteochondrosis in a four-month-old foal. (3366111)
1988
25
Osteochondrosis of the temporomandibular joint presenting as an apparent parotid mass. (3605957)
1987
26
General and local [corrected] aetiologic factors in canine osteochondrosis. (3672862)
1987
27
Observation on the development of osteochondrosis in young rats. (3795864)
1986
28
Osteochondrosis of the tarsal cuneiforms. (3995827)
1985
29
Cervical osteochondrosis and disc herniation. Eighteen years' use of interbody fusion by Cloward's technique in 755 cases. (6711365)
1984
30
Osteochondrosis dissecans of the knee. Results of operative treatment in juveniles. (6712421)
1984
31
Environmental zinc and cadmium pollution associated with generalized osteochondrosis, osteoporosis, and nephrocalcinosis in horses. (7056680)
1982
32
Fusarium-induced osteochondrosis (tibial dyschondroplasia) in chickens. (7147613)
1982
33
Osteochondrosis in feedlot cattle. (7257092)
1981
34
Age related changes and osteochondrosis in swine articular and epiphyseal cartilage: light ane electron microscopy. (7260732)
1981
35
Osteochondrosis of the shoulder joint of the horse. (7214917)
1981
36
Osteochondrosis in six breeds of slaughter pigs. (22039857)
1980
37
Osteochondrosis in the horse. II. Pathology. (233595)
1978
38
Osteochondrosis in domestic animals. Introduction. (233603)
1978
39
Osteochondrosis in domestic animals. I. Pathogenesis and pathology in pigs, horses, bulls, turkeys, and broilers, with comparative aspects on osteochondritis dissecans in man. (233590)
1978
40
Juvenile osteochondrosis. (271835)
1977
41
Osteochondrosis in the horse. (1110665)
1975
42
Osteochondrosis of the vertebrae in a dog. (5462583)
1970
43
TIBIA VARA (OSTEOCHONDROSIS DEFORMANS TIBIAE): A SURVEY OF SEVENTY-ONE CASES. (14213402)
1964
44
TIBIA VARA (OSTEOCHONDROSIS DEFORMANS TIBIAE OR BLOUNT'S DISEASE). TREATMENT AND FOLLOW-UP EXAMINATION. (14209243)
1964
45
Osteochondrosis of the capitellum (Panner's disease). Report of a case. (14456742)
1962
46
Osteochondrosis deformans juvenilis dorsi. (13770264)
1961
47
Osteochondrosis of the capitulum humeri (Panners' disease); report of a case. (13606439)
1958
48
Observations on the differential diagnosis and sequelae of juvenile vertebral osteochondrosis. (13228191)
1954
49
Tibia vara; (osteochondrosis deformans tibiae); a survey of 23 cases. (14923172)
1952
50
Preventive and conservative treatment of osteochondrosis dissecans. (14894212)
1951

Variations for Osteochondrosis

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Expression for genes affiliated with Osteochondrosis

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Search GEO for disease gene expression data for Osteochondrosis.

Pathways for genes affiliated with Osteochondrosis

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GO Terms for genes affiliated with Osteochondrosis

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Cellular components related to Osteochondrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:003109310.2IGF1, IGF2, TGFB1
2Golgi lumenGO:00057969.4ACAN, MMP16, TGFB1
3proteinaceous extracellular matrixGO:00055788.3ACAN, COL2A1, IHH, MMP16, TGFB1
4extracellular spaceGO:00056157.4CD36, COL2A1, IGF1, IGF2, IHH, OSM
5extracellular regionGO:00055767.3ACAN, COL2A1, IGF1, IGF2, OSM, SEMA3D

Biological processes related to Osteochondrosis according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of glycogen biosynthetic processGO:004572510.6IGF1, IGF2
2exocrine pancreas developmentGO:003101710.6IGF1, IGF2
3positive regulation of transcription regulatory region DNA bindingGO:200067910.6IGF1, TGFB1
4positive regulation of activated T cell proliferationGO:004210410.5IGF1, IGF2
5positive regulation of protein secretionGO:005071410.5IGF1, TGFB1
6mammary gland developmentGO:003087910.5IGF1, TGFB1
7cell activationGO:000177510.5IGF1, TGFB1
8protein kinase B signalingGO:004349110.5IGF1, TGFB1
9positive regulation of collagen biosynthetic processGO:003296710.3IHH, TGFB1
10morphogenesis of a branching structureGO:000176310.3IHH, TGFB1
11proteoglycan biosynthetic processGO:003016610.1ACAN, IGF1
12proteoglycan metabolic processGO:000602910.1COL2A1, IHH
13positive regulation of protein kinase B signalingGO:005189710.1IGF1, IGF2, TGFB1
14chondrocyte proliferationGO:003598810.1IHH, MMP16
15cartilage condensationGO:000150210.1ACAN, COL2A1
16positive regulation of epithelial cell proliferationGO:005067910.0IGF1, IHH, TGFB1
17endochondral ossificationGO:000195810.0COL2A1, MMP16
18inner ear developmentGO:004883910.0COL2A1, IGF1, TGFB1
19positive regulation of cell migrationGO:00303359.9IGF1, SEMA3D, TGFB1
20platelet degranulationGO:00025769.8CD36, IGF1, IGF2, TGFB1
21positive regulation of mitotic nuclear divisionGO:00458409.6IGF1, IGF2
22regulation of gene expressionGO:00104689.6COL2A1, IGF1, TGFB1
23extracellular matrix disassemblyGO:00226179.4ACAN, COL2A1, MMP16
24blood coagulationGO:00075969.4CD36, IGF1, IGF2, TGFB1
25positive regulation of MAPK cascadeGO:00434109.4CD36, IGF1, IGF2, OSM
26platelet activationGO:00301689.3CD36, IGF1, IGF2, TGFB1
27ossificationGO:00015039.2COL2A1, IGF2, IHH, MMP16
28skeletal system developmentGO:00015019.1ACAN, COL2A1, IGF1, IGF2, IHH
29positive regulation of peptidyl-tyrosine phosphorylationGO:00507318.9CD36, IGF1, IGF2, OSM, TGFB1
30positive regulation of cell proliferationGO:00082848.7IGF1, IGF2, IHH, OSM, TGFB1
31extracellular matrix organizationGO:00301988.6ACAN, COL2A1, MMP16, TGFB1
32positive regulation of transcription from RNA polymerase II promoterGO:00459448.0IGF1, IGF2, IHH, NR3C1, OSM, TGFB1

Molecular functions related to Osteochondrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1insulin-like growth factor receptor bindingGO:000515910.3IGF1, IGF2
2insulin receptor bindingGO:000515810.2IGF1, IGF2
3growth factor activityGO:00080838.8IGF1, IGF2, OSM, TGFB1

Sources for Osteochondrosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet