MCID: OST032
MIFTS: 32

Osteofibrous Dysplasia malady

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Osteofibrous Dysplasia

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Aliases & Descriptions for Osteofibrous Dysplasia:

Name: Osteofibrous Dysplasia 45 47 65
Jaffe-Campanacci Syndrome 45 65
 
Ossifying Fibroma 45 65
Intracortical Fibrous Dysplasia 45

Classifications:



External Ids:

UMLS65 C1709353, C0796000

Summaries for Osteofibrous Dysplasia

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Wikipedia:68 Osteofibrous dysplasia (also known as ossifying fibroma) is a rare, benign non-neoplastic condition with... more...

MalaCards based summary: Osteofibrous Dysplasia, also known as jaffe-campanacci syndrome, is related to juvenile ossifying fibroma and ossifying fibroma. An important gene associated with Osteofibrous Dysplasia is SPARC (Secreted Protein Acidic And Cysteine Rich), and among its related pathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and FGF signaling pathway. Affiliated tissues include bone, liver and t cells, and related mouse phenotypes are muscle and cardiovascular system.

Related Diseases for Osteofibrous Dysplasia

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Diseases related to Osteofibrous Dysplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 125)
idRelated DiseaseScoreTop Affiliating Genes
1juvenile ossifying fibroma12.7
2ossifying fibroma12.7
3familial ossifying fibroma12.6
4fibromatosis multiple non ossifying11.9
5chest wall lymphoma10.4NF1, SPARC
6chief cell adenoma10.3BGLAP, SPARC
7osteogenesis imperfecta, type iii10.3CD36, SPARC
8prion disease10.3BGLAP, SPARC
9diencephalic astrocytomas10.3GNAS, NF1
10breast cancer10.3
11bipolar disorder10.3
12hepatitis10.3
13cerebritis10.3
14caffey disease10.3BGLAP, CD36
15gray platelet syndrome10.3CD36, SPARC
16uterine benign neoplasm10.3GNAS, SPARC
17heavy chain disease10.3GNAS, SPARC
18osteogenesis imperfecta, type ii10.2BGLAP, CD36
19marcus gunn phenomenon10.2BGLAP, CD36
20bone inflammation disease10.2BGLAP, GNAS
21bone osteosarcoma10.2GNAS, SPARC
22cutaneous ganglioneuroma10.2SPP1, VIM
23epileptic encephalopathy, early infantile, 2610.2BGLAP, GNAS
24odontoma10.2CD36, VIM
25neuroblastoma10.1
26lung cancer10.1
27hiv-110.1
28abetalipoproteinemia10.1
29leprosy10.1
30anorexia nervosa10.1
31exfoliation syndrome10.1
32moyamoya disease10.1
33degenerative disc disease10.1
34insulinoma10.1
35leukemia10.1
36liver disease10.1
37thrombocytopenia10.1
38oral squamous cell carcinoma10.1
39apraxia10.1
40endocarditis10.1
41lymphoblastic leukemia10.1
42lepromatous leprosy10.1
43hydronephrosis10.1
44cerebral arteritis10.1
45cushing's syndrome10.1
46hemolytic-uremic syndrome10.1
47telangiectasis10.1
48urinary schistosomiasis10.1
49schistosomiasis10.1
50endogenous depression10.1

Graphical network of the top 20 diseases related to Osteofibrous Dysplasia:



Diseases related to osteofibrous dysplasia

Symptoms for Osteofibrous Dysplasia

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Drugs & Therapeutics for Osteofibrous Dysplasia

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Osteofibrous Dysplasia

Genetic Tests for Osteofibrous Dysplasia

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Anatomical Context for Osteofibrous Dysplasia

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MalaCards organs/tissues related to Osteofibrous Dysplasia:

33
Bone, Liver, T cells, Prostate, Endothelial, Temporal lobe, Tongue

Animal Models for Osteofibrous Dysplasia or affiliated genes

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MGI Mouse Phenotypes related to Osteofibrous Dysplasia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.1CD36, GNAS, NF1, SPP1, VIM
2MP:00053857.2CD36, GNAS, KRT1, NF1, SPP1, VIM
3MP:00053767.2CD36, GNAS, KRT1, NF1, SPARC, SPP1
4MP:00053787.1CD36, GNAS, KRT1, NF1, SPARC, SPP1
5MP:00053977.0CD36, GNAS, KRT1, NF1, SPARC, SPP1
6MP:00053876.7CD36, GNAS, KRT1, NF1, SPARC, SPP1

Publications for Osteofibrous Dysplasia

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Articles related to Osteofibrous Dysplasia:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
The Urine Proteome Profile Is Different in Neuromyelitis Optica Compared to Multiple Sclerosis: A Clinical Proteome Study. (26460890)
2015
2
Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis. (25786116)
2015
3
Re: Penile Corporoplasty with Yachia's Technique for Peyronie's Disease: Single Center Experience with 117 Patients. (24411890)
2014
4
Adenovirus vector-mediated FAM176A overexpression induces cell death in human H1299 non-small cell lung cancer cells. (24257118)
2014
5
Capillary malformation associated with multiple accessory tragi. (25201870)
2014
6
Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice. (24714692)
2014
7
Assessment of regulatory T cells in childhood immune thrombocytopenic purpura. (24298390)
2013
8
Unusual variants of choledochal cyst: how to classify. (23574833)
2013
9
Peripheral neuropathy for dermatologists: what if not diabetic neuropathy? (24144251)
2013
10
Computational analysis of C-reactive protein for assessment of molecular dynamics and interaction properties. (23494263)
2013
11
Vaccination and the onset of dravet syndrome. (21852883)
2011
12
Protection by neuroglobin and cell-penetrating peptide-mediated delivery in vivo: a decade of research. Comment on Cai et al: TAT-mediated delivery of neuroglobin protects against focal cerebral ischemia in mice. Exp Neurol. 2011; 227(1): 224-31. (21620833)
2011
13
High-dose insulin: a consecutive case series in toxin-induced cardiogenic shock. (21819291)
2011
14
The role of the epinephrine test in the diagnosis and management of children suspected of having congenital long QT syndrome. (19957170)
2010
15
Dendritic cell nuclear protein-1, a novel depression-related protein, upregulates corticotropin-releasing hormone expression. (20693543)
2010
16
Survival of patients diagnosed with either colorectal mucinous or non-mucinous adenocarcinoma: a population-based study in Canada. (19287969)
2009
17
Quality of life of children and adolescents with rheumatic fever. (19830356)
2009
18
Asthma and atopy are associated with chromosome 17q21 markers in Chinese children. (19175592)
2009
19
LRRK2 screening in a Canadian Parkinson's disease cohort. (17803033)
2007
20
The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy. (17354258)
2007
21
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas. (16570926)
2006
22
Antiphospholipid-mediated thrombosis: interplay between anticardiolipin antibodies and vascular cells. (16444433)
2006
23
Phase II evaluation of docetaxel plus exisulind in patients with androgen independent prostate carcinoma. (16891869)
2006
24
Choledocholithiasis: evolving standards for diagnosis and management. (16718834)
2006
25
The expression of iASPP in acute leukemias. (15607367)
2005
26
Differential expression of p63 isotypes (DeltaN and TA) in salivary gland neoplasms: biological and diagnostic implications. (16084953)
2005
27
Clinical pharmacokinetic monitoring of itraconazole is warranted in only a subset of patients. (15905803)
2005
28
Re: Pediatric ceftriaxone nephrolithiasis. (16094092)
2005
29
Outcomes of unrelated cord blood transplants and allogeneic-related hematopoietic stem cell transplants in children with high-risk acute lymphocytic leukemia. (15361908)
2004
30
Asymptomatic severe aortic coarctation in an 80-year-old man. (15745298)
2004
31
Juvenile hyaline fibromatosis. (15330966)
2004
32
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation. (15020295)
2004
33
Vivitrex, an injectable, extended-release formulation of naltrexone, provides pharmacokinetic and pharmacodynamic evidence of efficacy for 1 month in rats. (12931140)
2003
34
Low frequency of cytotoxic T lymphocytes against the novel HLA-A*0201-restricted JC virus epitope VP1(p36) in patients with proven or possible progressive multifocal leukoencephalopathy. (14581528)
2003
35
Increased influence of genetic variation on PON1 activity in neonates. (12928148)
2003
36
Effects of rabeprazole, lansoprazole and omeprazole on intragastric pH in CYP2C19 extensive metabolizers. (12269976)
2002
37
A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane. (11937503)
2002
38
Metastatic potential of human uroepithelial cancer cells is not dependent on their adhesion to E-selectin. (10810376)
2000
39
Pedophilia and temporal lobe disturbances. (10678516)
2000
40
Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria. (9379894)
1997
41
Neurovascular compression at the ventrolateral medulla in autosomal dominant hypertension and brachydactyly. (9303020)
1997
42
Goodpasture syndrome: selective removal of anti-alpha 3 (IV) collagen autoantibodies. A potential therapeutic alternative to plasmapheresis. (8864724)
1996
43
Immunological effects of the anti-IL-2 receptor monoclonal antibody BT 563 in liver allografted patients. (8581408)
1995
44
Analysis of the binding of pro-urokinase and urokinase-plasminogen activator inhibitor-1 complex to the low density lipoprotein receptor-related protein using a Fab fragment selected from a phage-displayed Fab library. (7538122)
1995
45
Transesophageal echocardiographic diagnosis of the superior vena cava syndrome resulting from aortic dissection: a multiplane study. (7917352)
1994
46
Kinetics of Trolox C oxidation by lactoperoxidase compound II. (8333845)
1993
47
Adrenocorticotropic hormone, beta-endorphin, cortisol, growth hormone and prolactin circulating levels in nineteen athletes before and after half-marathon and marathon. (1665889)
1991
48
Mortality in cases of asbestosis diagnosed by a pneumoconiosis medical panel. (3660318)
1987
49
Northern sylvatic helminthiasis. (5693140)
1968
50
CONGENITAL HEART DISEASE WITH THE IVEMARK SYNDROME AND ABSENCE OF THE INFERIOR VENA CAVA. (14275331)
1965

Variations for Osteofibrous Dysplasia

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Expression for genes affiliated with Osteofibrous Dysplasia

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Search GEO for disease gene expression data for Osteofibrous Dysplasia.

Pathways for genes affiliated with Osteofibrous Dysplasia

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GO Terms for genes affiliated with Osteofibrous Dysplasia

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Cellular components related to Osteofibrous Dysplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1membrane-bounded vesicleGO:003198810.0BGLAP, SPARC
2dendriteGO:00304259.1BGLAP, GNAS, NF1

Biological processes related to Osteofibrous Dysplasia according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1response to gravityGO:000962910.2BGLAP, SPARC
2negative regulation of transcription factor import into nucleusGO:004299210.0CD36, NF1
3negative regulation of angiogenesisGO:00165259.9NF1, SPARC
4regulation of bone resorptionGO:00451249.9BGLAP, NF1
5bone developmentGO:00603489.9BGLAP, GNAS
6cognitionGO:00508909.9GNAS, NF1
7negative regulation of endothelial cell proliferationGO:00019379.9NF1, SPARC
8response to vitamin DGO:00332809.7BGLAP, SPP1
9cellular response to growth factor stimulusGO:00713639.6BGLAP, SPARC
10regulation of angiogenesisGO:00457659.6KRT1, NF1

Sources for Osteofibrous Dysplasia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet