OI
MCID: OST005
MIFTS: 70

Osteogenesis Imperfecta (OI) malady

Bone diseases category

Summaries for Osteogenesis Imperfecta

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8Disease Ontology, 21Genetics Home Reference, 42NIH Rare Diseases, 33MedlinePlus, 63Wikipedia, 46OMIM, 32MalaCards
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MedlinePlus:33 Osteogenesis imperfecta (oi) is a genetic disorder in which bones break easily. sometimes the bones break for no known reason. oi can also cause weak muscles, brittle teeth, a curved spine, and hearing loss. oi is caused by one of several genes that aren't working properly. when these genes don't work, it affects how you make collagen, a protein that helps make bones strong. oi can range from mild to severe, and symptoms vary from person to person. a person may have just a few or as many as several hundred fractures in a lifetime. no single test can identify oi. your doctor using your medical and family history, physical exam, and imaging and lab tests to diagnose it. your doctor may also test your collagen (from skin) or genes (from blood). there is no cure, but you can manage symptoms. treatments include exercise, pain medicine, physical therapy, wheelchairs, braces, and surgery. nih: national institute of arthritis and musculoskeletal and skin diseases

MalaCards: Osteogenesis Imperfecta, also known as brittle bone disease, is related to osteogenesis imperfecta type i and osteogenesis imperfecta type iii. An important gene associated with Osteogenesis Imperfecta is COL1A2 (collagen, type I, alpha 2), and among its related pathways are Platelet Adhesion to exposed collagen and Osteoblast Signaling. The drugs calcitonin and salmon calcitonin and the compounds procollagen and estrogen have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and testes, and related mouse phenotypes are skeleton and growth/size.

Disease Ontology:8 An osteochondrodysplasia that has material basis in a deficiency in type-i collagen which results in brittle bones and defective connective tissue.

Genetics Home Reference:21 Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affect the bones. The term "osteogenesis imperfecta" means imperfect bone formation. People with this condition have bones that break easily, often from mild trauma or with no apparent cause. Multiple fractures are common, and in severe cases, can occur even before birth. Milder cases may involve only a few fractures over a person's lifetime.

NIH Rare Diseases:42 Osteogenesis imperfecta (oi) is a group of genetic disorders that mainly affect the bones. people with this condition have bones that break easily, often from mild trauma or with no apparent cause. multiple fractures are common, and in severe cases, can occur even before birth. milder cases may involve only a few fractures over a person's lifetime. there are at least eight recognized forms of osteogenesis imperfecta, designated type i through type viii. the types can be distinguished by their signs and symptoms, as well as by genetic factors. depending on the genetic cause, oi may be inherited in an autosomal dominant (more commonly) or autosomal recessive pattern. last updated: 10/3/2011

Wikipedia:63 Osteogenesis imperfecta (OI and sometimes known as brittle bone disease, or \"Lobstein syndrome\") is a... more...

Description from OMIM:46 610854, 166200, 259420, 610968, 166220 610915, 610682, 166210, 259440, 166240 more

Aliases & Classifications for Osteogenesis Imperfecta

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8Disease Ontology, 63Wikipedia, 42NIH Rare Diseases, 20GeneTests, 22GTR, 21Genetics Home Reference, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 34MeSH, 46OMIM, 56SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Bone diseases


Aliases & Descriptions:

osteogenesis imperfecta 8 63 42 20 22 21 10 44 33 60
brittle bone disease 8 63 42 21
fragilitas ossium 63 42 21
vrolik disease 63 42 21
oi 63 42 21
osteopsathyrosis 8 63
osteogenesis imperfecta, recessive perinatal lethal 60
ekman-lobstein disease 63
lobstein's syndrome 8
vrolik's disease 8


Related Diseases for Osteogenesis Imperfecta

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17GeneCards, 18GeneDecks
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Diseases in the Osteogenesis Imperfecta Type Iii family:

osteogenesis imperfecta Osteogenesis Imperfecta Type I
Osteogenesis Imperfecta Type 9 Osteogenesis Imperfecta Type 1a
Osteogenesis Imperfecta Type 2a Osteogenesis Imperfecta Type 2b
Osteogenesis Imperfecta Type 4 Osteogenesis Imperfecta Type 5
Osteogenesis Imperfecta Type 6 Osteogenesis Imperfecta Type 7
Osteogenesis Imperfecta Type 8 Crtap-Related Osteogenesis Imperfecta
Lepre1-Related Osteogenesis Imperfecta Ppib-Related Osteogenesis Imperfecta
Fkbp10-Related Osteogenesis Imperfecta Serpinf1-Related Osteogenesis Imperfecta
Serpinh1-Related Osteogenesis Imperfecta Sp7-Related Osteogenesis Imperfecta
Ifitm5-Related Osteogenesis Imperfecta Bmp1-Related Osteogenesis Imperfecta
Osteogenesis Imperfecta Type Xi Osteogenesis Imperfecta Type X
Osteogenesis Imperfecta Type Xii Osteogenesis Imperfecta Type Xiii
Osteogenesis Imperfecta, Type Ii Osteogenesis Imperfecta, Type Xiv
Osteogenesis Imperfecta, Type Xv

Diseases related to Osteogenesis Imperfecta via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 159)
idRelated DiseaseScoreTop Affiliating Genes
1osteogenesis imperfecta type i31.8COL1A1, COL1A2
2osteogenesis imperfecta type iii31.4COL1A2, COL1A1
3dentinogenesis imperfecta31.2CD36, LEPRE1, COL1A1, IBSP, CRTAP, DSPP
4osteogenesis imperfecta type 630.9BP10, FKBP10
5osteogenesis imperfecta, type ii30.8COL1A1, COL1A2
6osteogenesis imperfecta type 430.8COL1A1, COL1A2
7ehlers-danlos syndrome30.8COL1A1, COL1A2, CD36, DSPP, COL2A1
8osteoporosis30.8SP7, CD36, IBSP, BGLAP, COL2A1, COL1A2
9col1a1/2-related osteogenesis imperfecta30.6COL1A1, COL1A2
10collagen disease30.6COL1A1, CD36, COL2A1
11osteonecrosis30.5BGLAP
12fibrous dysplasia30.3BGLAP, IBSP
13otosclerosis30.3COL1A1, CD36, COL1A2
14idiopathic juvenile osteoporosis30.3COL1A1, BGLAP
15osteochondrodysplasia30.1COL2A1
16connective tissue disease30.1COL2A1, COL1A1, DSPP, CD36, COL1A2
17rickets30.1CD36, BGLAP
18secondary syphilis30.1IBSP, BGLAP, CD36
19hyperparathyroidism30.1BGLAP
20dwarfism30.1COL2A1
21osteoarthritis30.1COL1A1, COL2A1, BGLAP, COL1A2, IBSP, DSPP
22bone fracture10.6
23osteogenesis imperfecta type 510.6
24osteogenesis imperfecta type 910.6
25osteogenesis imperfecta type 810.5
26osteogenesis imperfecta type xiii10.5
27osteogenesis imperfecta type 710.5
28osteogenesis imperfecta type 2a10.5
29osteogenesis imperfecta type xi10.5
30osteogenesis imperfecta type xii10.5
31osteogenesis imperfecta levin type10.4
32osteogenesis imperfecta type 1a10.4
33osteogenesis imperfecta type x10.4
34osteogenesis imperfecta, type xiv10.4
35osteogenesis imperfecta type 2b10.4
36osteogenesis imperfecta, type xv10.4
37congenital osteogenesis imperfecta - microcephaly - cataracts10.4
38high bone mass osteogenesis imperfecta10.4
39reflex sympathetic dystrophy10.3
40type i ehlers-danlos syndrome10.3
41cerebritis10.3
42spondylolysis10.3
43hypophosphatasia10.3
44breast cancer10.3
45dentinogenesis imperfecta 110.3
46osteoporosis-pseudoglioma syndrome10.3
47crtap-related osteogenesis imperfecta10.3
48ehlers-danlos/osteogenesis imperfecta syndrome10.3
49postural orthostatic tachycardia syndrome10.3
50spondylolisthesis10.2

Graphical network of the top 20 diseases related to Osteogenesis Imperfecta:



Diseases related to osteogenesis imperfecta

Clinical Features for Osteogenesis Imperfecta

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46OMIM
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Clinical features from OMIM:

610854,166200,259420,610968,166220,610915,610682,166210,259440,166240

Drugs & Therapeutics for Osteogenesis Imperfecta

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Osteogenesis Imperfecta

Drug clinical trials:

Search ClinicalTrials for Osteogenesis Imperfecta

Search NIH Clinical Center for Osteogenesis Imperfecta

Search CenterWatch for Osteogenesis Imperfecta

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Osteogenesis Imperfecta

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20GeneTests, 22GTR
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Genetic tests related to Osteogenesis Imperfecta:

id Genetic test Affiliating Genes
1 Osteogenesis Imperfecta20 22

Anatomical Context for Osteogenesis Imperfecta

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32MalaCards
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MalaCards organs/tissues related to Osteogenesis Imperfecta:

32
Bone, Skin, Testes, Bone marrow, Breast, Heart, Colon, Uterus, Lung, Skeletal muscle, Endothelial

Animal Models for Osteogenesis Imperfecta or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Osteogenesis Imperfecta:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053909.7CD36, CRTAP, IBSP, LEPRE1, GGT1, SERPINH1
2MP:00053789.7GGT1, LEPRE1, CD36, CRTAP, PPIB, BMP1
3MP:00053719.5SERPINH1, GGT1, LEPRE1, FKBP10, IBSP, COL1A1

Publications for Osteogenesis Imperfecta

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50PubMed
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Articles related to Osteogenesis Imperfecta:

(show top 50)    (show all 839)
idTitleAuthorsYear
1
Induced Ablation of Bmp1 and Tll1 produces Osteogenesis Imperfecta in Mice. (24419319)
2014
2
Local transplantation is an effective method for cell delivery in the osteogenesis imperfecta murine model. (24384938)
2014
3
Population screening for the mutation associated with osteogenesis imperfecta in dachshunds. (23315765)
2013
4
Management of Hangman's Fractures and a Subaxial Compression Fracture in Two Children With Osteogenesis Imperfecta. (24393194)
2013
5
Thoracic elongation in type III osteogenesis imperfecta patients with thoracic insufficiency syndrome. (23138403)
2013
6
Oral bisphosphonates for paediatric osteogenesis imperfecta? (23927912)
2013
7
Osteogenesis imperfecta in cardiac surgery: response to letter of Dimitrakakis et al. (23430440)
2013
8
The identification of novel mutations in COL1A1, COL1A2, and LEPRE1 genes in Chinese patients with osteogenesis imperfecta. (21667357)
2012
9
Right ventricular and pulmonary arterial dimensions in adults with osteogenesis imperfecta. (22459302)
2012
10
Osteogenesis imperfecta and bone marrow transplant. (22367768)
2012
11
Distal patellar tendon avulsion fracture in a football player with osteogenesis imperfecta. (21717214)
2012
12
Relationship between vitamin D status and bone mineralization, mass, and metabolism in children with osteogenesis imperfecta: histomorphometric study. (21544864)
2011
13
Exome sequencing identifies truncating mutations in human SERPINF1 in autosomal-recessive osteogenesis imperfecta. (21353196)
2011
14
Fassier-Duval femoral rodding in children with osteogenesis imperfecta receiving bisphosphonates: functional outcomes at one year. (22654983)
2011
15
The severity of osteogenesis imperfecta: a comparison to the relative free energy differences of collagen model peptides. (20945334)
2011
16
Zoledronic acid treatment in children with osteogenesis imperfecta. (21293106)
2011
17
A novel DHPLC-based procedure for the analysis of COL1A1 and COL1A2 mutations in osteogenesis imperfecta. (21884818)
2011
18
Biochemical bone markers in the assessment and pamidronate treatment of children and adolescents with osteogenesis imperfecta. (20726960)
2010
19
Complete COL1A1 allele deletions in osteogenesis imperfecta. (21113976)
2010
20
Anesthetic implications for the patient with osteogenesis imperfecta. (20977129)
2010
21
Growth of infants with osteogenesis imperfecta treated with bisphosphonate. (19371278)
2009
22
Shin splints: an unexpected effect of bisphosphonates in osteogenesis imperfecta. (19352259)
2009
23
Osteogenesis imperfecta type III with intracranial hemorrhage and brachydactyly associated with mutations in exon 49 of COL1A2. (19208385)
2009
24
Mutation and polymorphism spectrum in osteogenesis imperfecta type II: implications for genotype-phenotype relationships. (18996919)
2009
25
A novel arginine-to-cysteine substitution in the triple helical region of the alpha1(I) collagen chain in a family with an osteogenesis imperfecta/Ehlers-Danlos phenotype. (18028452)
2008
26
Neurosurgical implications of osteogenesis imperfecta in children. Report of 4 cases. (18352768)
2008
27
Molecular diagnosis of osteogenesis imperfecta type I]. (19145934)
2008
28
Treatment of osteogenesis imperfecta: who, why, what? (18174695)
2007
29
Increased resorptive activity and accompanying morphological alterations in osteoclasts derived from the oim/oim mouse model of osteogenesis imperfecta. (17668424)
2007
30
Early bisphosphonate treatment in infants with severe osteogenesis imperfecta. (16887429)
2006
31
Further safety enhancement of a specialized power assisted tricycle for a child with osteogenesis imperfecta type III and design of an adjustble hand power tricycle. (16817593)
2006
32
Intravenous pamidronate treatment in children with moderate to severe osteogenesis imperfecta: assessment of indices of dual-energy X-ray absorptiometry and bone metabolic markers during the first year of therapy. (15003801)
2004
33
Osteogenesis imperfecta type VI: a form of brittle bone disease with a mineralization defect. (11771667)
2002
34
Osteogenesis imperfecta and other skeletal dysplasias presenting with increased nuchal translucency in the first trimester. (11223845)
2001
35
Osteogenesis imperfecta: mosaicism and refinement of the genotype- phenotype map in OI type III. (10408781)
1999
36
Premature chain termination is a unifying mechanism for COL1A1 null alleles in osteogenesis imperfecta type I cell strains. (8808594)
1996
37
Immunoreactivity of tenascin-C in dentin matrix in dentinogenesis imperfecta associated with osteogenesis imperfecta. (8655763)
1996
38
Genetic counselling on brittle grounds: recurring osteogenesis imperfecta due to parental mosaicism for a dominant mutation. (7720740)
1995
39
Recurrence of osteogenesis imperfecta because of paternal mosaicism: Gly862-->Ser substitution in a type I collagen gene (COL1A1). (7789952)
1995
40
Severe (type III) osteogenesis imperfecta due to glycine substitutions in the central domain of the collagen triple helix. (7881420)
1994
41
A cysteine for glycine substitution at position 175 in an alpha 1 (I) chain of type I collagen produces a clinically heterogeneous form of osteogenesis imperfecta. (8339541)
1993
42
Paternal mosaicism for a COL1A1 dominant mutation (alpha 1 Ser-415) causes recurrent osteogenesis imperfecta. (8364588)
1993
43
Anencephaly in a fetus with osteogenesis imperfecta: early diagnosis by transvaginal sonography. (1475252)
1992
44
Substitutions for glycine alpha 1-637 and glycine alpha 2-694 of type I procollagen in lethal osteogenesis imperfecta. The conformational strain on the triple helix introduced by a glycine substitution can be transmitted along the helix. (1874719)
1991
45
Total body bone mineral and tartrate-resistant acid phosphatase levels in type I and III osteogenesis imperfecta. (1823391)
1991
46
Substitution of cysteine for glycine within the carboxyl-terminal telopeptide of the alpha 1 chain of type I collagen produces mild osteogenesis imperfecta. (3170557)
1988
47
Substitution of arginine for glycine 664 in the collagen alpha 1(I) chain in lethal perinatal osteogenesis imperfecta. Demonstration of the peptide defect by in vitro expression of the mutant cDNA. (3403550)
1988
48
Prenatal diagnosis of osteogenesis imperfecta type III. (3547385)
1987
49
Lethal osteogenesis imperfecta resulting from a single nucleotide change in one human pro alpha 1(I) collagen allele. (3016737)
1986
50
The amino-acid composition of human hard tissue collagens in osteogenesis imperfecta and dentinogenesis imperfecta. (4710795)
1973

Genetic Variations for Osteogenesis Imperfecta

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Expression for genes affiliated with Osteogenesis Imperfecta

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Osteogenesis Imperfecta

Search GEO for disease gene expression data for Osteogenesis Imperfecta.

Pathways for genes affiliated with Osteogenesis Imperfecta

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53Reactome, 37NCBI BioSystems Database, 49PharmGKB, 12EMD Millipore, 29KEGG, 51QIAGEN
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Pathways related to Osteogenesis Imperfecta according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.4COL1A2, COL1A1
210.3COL1A1, IBSP
310.3COL1A2, COL1A1, CD36
410.3COL1A2, CD36, COL1A1
510.3BMP1, COL1A1, COL1A2
610.3BMP1, COL1A2, COL1A1
7
Cell adhesion ECM remodeling
Hide members
10.3COL2A1, COL1A2, COL1A1
810.3COL2A1, COL1A2, COL1A1
910.3COL1A1, COL2A1, COL1A2
10
Hide members
10.3COL2A1, COL1A2, COL1A1
1110.2COL1A1, COL2A1, IBSP, COL1A2
12
Hide members
10.2COL2A1, COL1A2, COL1A1, IBSP
13
Development Hedgehog and PTH signaling pathways in bone and cartilage development
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10.1IBSP, BGLAP, COL1A1, COL1A2, COL2A1
14
Hide members
10.0COL1A1, SERPINH1, LEPRE1, CRTAP, PPIB, BMP1

Compounds for genes affiliated with Osteogenesis Imperfecta

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44Novoseek, 11DrugBank, 49PharmGKB, 24HMDB, 28IUPHAR
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Compounds related to Osteogenesis Imperfecta according to GeneCards/GeneDecks:

(show top 50)    (show all 55)
idCompoundScoreTop Affiliating Genes
1procollagen4410.8COL2A1, COL1A2
2estrogen4410.7GLYAT
3Collagenase1110.7COL1A2, COL1A1, COL2A1
4ti6al4v4410.7BGLAP, CD36
5carbodiimide4410.7RNASE1, COL1A2, COL1A1
6ibandronate44 1111.7IBSP, BGLAP, CD36
7calcium carbonate4410.6CD36, DSPP, BGLAP
8tartrate4410.6BGLAP, CD36, DSPP
9nppa4410.6COL1A2, COL1A1
10polyglycolic acid4410.6BGLAP, DSPP, CD36
11chitosan4410.6CD36, IBSP, BGLAP
12chlorhexidine gluconate4410.6SERPINH1, DSPP
13alizarin4410.6CD36, IBSP, BGLAP, SP7
14acetone4410.6DSPP, CD36, RNASE1
15titanium4410.6BGLAP, CD36, IBSP
16zoledronic acid4410.6IBSP, BGLAP, CD36
17methylmethacrylate4410.6IBSP, DSPP
18deoxypyridinoline4410.6BGLAP, IBSP, CD36
19pyridinoline4410.6COL2A1, BGLAP, CD36, IBSP
20alendronate44 49 1112.6BGLAP, DSPP, CD36
2122-oxacalcitriol4410.6BGLAP, CD36
22hydroxyapatite4410.6BGLAP, DSPP, IBSP, CD36
23fluorescein44 1111.6DSPP, BGLAP, SERPINF1
24alginate4410.6CD36, BGLAP, COL2A1
25glycosaminoglycan4410.5SERPINF1, CD36, IBSP, COL2A1, COL1A1
26hydroxyproline44 11 2412.5CD36, IBSP, BGLAP, COL1A1, COL2A1
27etidronate4410.5CD36, BGLAP
28hydroxylysine4410.5COL1A1, COL2A1
29glutamate4410.5IBSP, RNASE1, BMP1
30teriparatide44 1111.5BGLAP, CD36
31serine4410.5RNASE1, COL2A1, SERPINF1, COL1A2, BGLAP, BMP1
32silver nitrate4410.4DSPP, CD36
33guanidine hydrochloride4410.4RNASE1, BGLAP, DSPP
34vitamin d4410.4COL2A1, COL1A2, COL1A1, BGLAP, DSPP, IBSP
35grgds4410.4IBSP, CD36
36heparin44 28 11 2413.4BGLAP, IBSP, BMP1, PPIB, CD36, RNASE1
37oligonucleotide4410.3COL1A2, IBSP, COL2A1, RNASE1, COL1A1, SERPINH1
38tannins4410.3CD36, DSPP
39h2o24410.3RNASE1, BGLAP, SERPINF1, GGT1, DSPP, CD36
40vegf4410.3COL1A1, BGLAP, SERPINF1, SP7, SERPINH1, RNASE1
41arginine4410.3RNASE1, DSPP, BMP1, GGT1, BGLAP, COL1A1
42aspartate4410.3RNASE1, COL1A2, GGT1, DSPP, BMP1, COL1A1
43dexamethasone44 49 28 1113.3COL2A1, DSPP, COL1A1, BGLAP, IBSP, SP7
44alanine4410.3BMP1, BGLAP, RNASE1, COL1A1, GGT1, COL2A1
451,25 dihydroxy vitamin d34410.3COL1A1, BGLAP, IBSP
46ascorbic acid44 2411.2COL2A1, SP7, DSPP, GGT1, SERPINH1, LEPRE1
47alpha tocopherol4410.1BGLAP, GGT1, CD36
48cysteine4410.1IBSP, COL2A1, COL1A1, BGLAP, BMP1, DSPP
49calcium44 49 11 2413.1COL2A1, RNASE1, COL1A2, DSPP, BMP1, IBSP
50vitamin k24410.0CD36, BGLAP

GO Terms for genes affiliated with Osteogenesis Imperfecta

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16Gene Ontology
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Cellular components related to Osteogenesis Imperfecta according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1collagen type IGO:00558410.3COL1A2, COL1A1
2proteinaceous extracellular matrixGO:00557810.2LEPRE1, DSPP, CRTAP, BMP1
3endoplasmic reticulum lumenGO:00578810.0COL2A1, SERPINH1, LEPRE1, FKBP10, CRTAP, PPIB
4extracellular spaceGO:00561510.0COL2A1, COL1A2, COL1A1, BGLAP, BMP1, SERPINH1
5extracellular regionGO:0055769.6RNASE1, BMP1, IBSP, BGLAP, COL1A1, COL1A2

Biological processes related to Osteogenesis Imperfecta according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1skin morphogenesisGO:04358910.5COL1A1, COL1A2
2collagen biosynthetic processGO:03296410.5COL1A1, SERPINH1
3osteoblast differentiationGO:00164910.5SP7, BGLAP, COL1A1
4cartilage development involved in endochondral bone morphogenesisGO:06035110.5COL1A1, COL2A1
5collagen fibril organizationGO:03019910.4SERPINH1, LEPRE1, COL1A1, COL1A2, COL2A1
6regulation of bone mineralizationGO:03050010.3BGLAP, IFITM5
7ossificationGO:00150310.3DSPP, BMP1, IBSP
8collagen catabolic processGO:03057410.3COL1A1, COL1A2, COL2A1
9skeletal system developmentGO:00150110.3COL2A1, DSPP, BMP1, BGLAP, COL1A1, COL1A2
10extracellular matrix disassemblyGO:02261710.2COL2A1, COL1A1, COL1A2
11extracellular matrix organizationGO:03019810.1SERPINH1, LEPRE1, CRTAP, PPIB, BMP1, IBSP
12protein heterotrimerizationGO:07020810.1COL1A1, COL1A2

Molecular functions related to Osteogenesis Imperfecta according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix structural constituentGO:00520110.3DSPP, COL1A1, COL1A2
2platelet-derived growth factor bindingGO:04840710.0COL1A1, COL1A2, COL2A1

Products for genes affiliated with Osteogenesis Imperfecta

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  • Antibodies
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Sources for Osteogenesis Imperfecta

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet