MCID: OST011
MIFTS: 48

Osteomalacia malady

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Osteomalacia

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Aliases & Descriptions for Osteomalacia:

Name: Osteomalacia 11 46 13 48 66
 
Adult Rickets 66

Classifications:



External Ids:

Disease Ontology11 DOID:10573
ICD9CM30 268.2
NCIt43 C26838

Summaries for Osteomalacia

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NIH Rare Diseases:46 Osteomalacia is a disease that is characterized by a weakening of the bone, often due to a deficiency of vitamin d. this vitamin supports the development of the bones of the body, so when there are low levels of vitamin d, the bones are not strong enough. symptoms of osteomalacia can include muscle weakness, bone pain, and walking with a waddling gait. pain is especially likely to occur in the lower back, hips, and legs. the weakening of the bones may also cause them to easily fracture.  osetomalacia can be caused by having a low level of vitamin d in the diet or lack of sun exposure. the condition may also be the result of an underlying disease such as celiac disease, or kidney or liver disorders.  diagnosis of osteomalacia is possible through blood or urine tests to check for vitamin d levels or a bone biopsy. treatment options include supplementing the diet with more vitamin d or calcium. any underlying condition will also need to be treated.   last updated: 9/23/2016

MalaCards based summary: Osteomalacia, also known as adult rickets, is related to oncogenic osteomalacia and axial osteomalacia, and has symptoms including uraemia odour An important gene associated with Osteomalacia is DMP1 (Dentin Matrix Acidic Phosphoprotein 1), and among its related pathways are Osteoblast Signaling and Etoposide Pathway, Pharmacokinetics/Pharmacodynamics. Affiliated tissues include bone, bone and kidney, and related mouse phenotypes are craniofacial and renal/urinary system.

Disease Ontology:11 A bone remodeling disease that has material basis in a vitamin d deficiency which results in softening located in bone.

Wikipedia:69 Osteomalacia is the softening of the bones caused by impaired bone metabolism primarily due to... more...

Related Diseases for Osteomalacia

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Diseases related to Osteomalacia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 194)
idRelated DiseaseScoreTop Affiliating Genes
1oncogenic osteomalacia12.5
2axial osteomalacia12.3
3colorectal cancer, hereditary nonpolyposis, type 410.6DMP1, FGF23
4jacobsen syndrome10.6FGF23, PHEX
5hypophosphatemic rickets10.6
6familial wilms tumor 210.6FGF23, PHEX
7atelosteogenesis10.5FGF23, PHEX
8renal osteodystrophy10.5
9hyperostosis10.4DMP1, FGF23, PHEX
10spastic ataxia10.4DMP1, FGF23, PHEX
11rickets10.4
12hypophosphatasia10.4
13cystic echinococcosis10.4FGF23, PTH
14prostate cancer, hereditary, x-linked 210.4FGF23, PHEX
15peroxisome biogenesis disorder 2a10.4FGF23, MEPE, PHEX
16hypercalciuria, absorptive10.4CASR, VDR
17testicular microlithiasis10.3FGF23, PTH
18hyperparathyroidism10.3
19ochronosis10.3ALPL, PHEX
20opthalmomandibulomelic dysplasia10.3PTH, VDR
21fanconi syndrome10.3
22cervix disease10.2PTH, VDR
23osteoporosis10.2
24renal tubular acidosis10.1
25testicular brenner tumor10.1CASR, PTH
26substance dependence10.1FGF23, PTH, VDR
27adult syndrome10.1
28achondrogenesis10.1BGLAP, PTH
29hypophosphatemia10.1
30cranial nerve palsy10.1BGLAP, PTH
31primary hyperparathyroidism10.1
32hemangiopericytoma10.0
33periodic paralyses10.0CALCA, FGF23
34retinal vasculitis10.0ALPL, CASR
35celiac disease10.0
36hepatitis10.0
37neurofibromatosis10.0
38prostatitis10.0
39osteitis fibrosa10.0
40obesity, severe bmiq99.9BGLAP, PTH
41hepatitis b9.9
42primary biliary cirrhosis9.9
43spondylitis9.9
44paraneoplastic syndromes9.9
45t cell deficiency9.9CASR, FGF23, PTH
46hypochondrogenesis9.9CALCA, PTH
47impotence9.9CALCA, PTH
48prostate cancer9.9
49myeloma9.9
50myopathy9.9

Comorbidity relations with Osteomalacia via Phenotypic Disease Network (PDN):


OsteoporosisDeficiency Anemia
Acute Cystitis

Graphical network of the top 20 diseases related to Osteomalacia:



Diseases related to osteomalacia

Symptoms for Osteomalacia

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UMLS symptoms related to Osteomalacia:


uraemia odour

Drugs & Therapeutics for Osteomalacia

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Drugs for Osteomalacia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1vitamin dPhase 4, Phase 1, Phase 21607
2
ErgocalciferolNutraceuticalPhase 4, Phase 1, Phase 2121150-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
3
CholecalciferolNutraceuticalPhase 4, Phase 1, Phase 282667-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
4retinolNutraceuticalPhase 4450
5
Vitamin ANutraceuticalPhase 445011103-57-4, 68-26-8445354
Synonyms:
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
.alpha.lin
.alpha.sterol
.beta.-Retinol
11103-57-4
13123-33-6
1341-18-0
1406-67-3
17104-91-5
1rbp
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonate-traen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer
4-06-00-04133 (Beilstein Handbook Reference)
53637-36-8
5979-23-7
68-26-8
95144_FLUKA
95144_SIGMA
95146_FLUKA
95146_SIGMA
A-Mulsal
A-Sol
A-Vi-Pel
A-Vitan
AC-11701
AC1L9HU3
AC1Q7BU9
ACON
ALL-TRANS RETINOL (SEE ALSO RETINOID PROJECT 1)
AR-1L3057
ATAV
Afaxin
Agiolan
Agoncal
Alcohol 9,13-dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraen-15-ol
Alcovit A
All Trans Retinol
All-trans retinol
All-trans-Retinol
Alphalin
Alphasterol
Anatola
Anatola A
Anti-infective vitamin
Antixerophthalmic vitamin
Antixerophthalmisches Vitamin
Aoral
Apexol
Apostavit
Aquasol A Parenteral
Aquasynth
Atars
Avibon
Avita
Avitol
Axerol
Axerophthol
Axerophtholum
BIDD:PXR0102
BRN 0403040
Bentavit A
Biosterol
C00473
C17276
C20H30O
CCRIS 5444
CHEBI:17336
CHEMBL986
CID445354
Chocola A
Cylasphere
D014801
D06543
DB00162
Del-VI-A
Disatabs Tabs
Dofsol
Dohyfral A
EINECS 200-683-7
EINECS 234-328-2
Epiteliol
HMS1921B04
HMS2092L13
HMS501I08
HSDB 815
Hi-A-Vita
Homagenets Aoral
Homagenets aorl
Hydrovit A
IDI1_000486
LMPR01090001
LPK
LS-1578
Lard Factor
M.V.C. 9+3
M.V.I.-12
 
MLS001066379
MLS001074751
MolPort-001-785-962
Mvc Plus
Myvpack
NCGC00091784-01
NCGC00091784-02
NCGC00091784-03
NCGC00091784-04
NCGC00091784-05
NCGC00091784-06
NSC 122759
NSC122759
Nio-A-Let
Oleovitamin A
Ophthalamin
Plivit A
Prepalin
R7632_SIGMA
Retin-11,12-t2-ol (9CI)
Retinol
Retinol [INN:BAN]
Retinol solution
Retinol, all-trans- (8CI)
Retinol-(cellular-retinol-binding-protein)
Retinolo
Retinolo [DCIT]
Retinolum
Retinolum [INN-Latin]
Retrovitamin A
Ro-a-vit
Rovimix A 500
SDCCGMLS-0066724.P001
SMP2_000102
SMR000112036
SPECTRUM1501203
ST057232
Sehkraft A
Solu-A
Spectrum5_000993
Spectrum5_001997
Super A
Testavol
Testavol S
Thalasphere
UNII-81G40H8B0T
UNII-G2SH0XKK91
Vaflol
Vafol
Veroftal
Vi-.alpha.
Vi-Alpha
Vi-Dom-A
Vi-a
Vio-A
Vitamin A
Vitamin A (Feed)
Vitamin A (USP)
Vitamin A alcohol
Vitamin A alcohol (VAN)
Vitamin A cryst
Vitamin A1
Vitamin A1 alcohol
Vitamin A1 alcohol, all trans
Vitamin- A
Vitamin- A alcohol
Vitamin- A alcohol solution
Vitamin- A1
Vitamin-?A
Vitamin-?A alcohol
Vitamin-?A alcohol solution
Vitamin-?A1
Vitamine A
Vitaminum A
Vitavel A
Vitavel-A
Vitpex
Vogan
Vogan-Neu
Vogan-nu
WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U2Q C1 C1
Wachstumsvitamin
ZINC03831417
Zinosan N
[11,12-3H]-Retinol
alin
all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
all-trans-Retinol
all-trans-Retinyl alcohol
all-trans-Vitamin A
all-trans-Vitamin A alcohol
all-trans-Vitamin A1
all-trans-retinol
all-trans-retinyl alcohol
all-trans-vitamin A alcohol
b-Retinol
beta-Retinol
retinol
tROL
trans-Retinol
trans-Retinol acid (Vitamin A)
trans-Vitamin A alcohol
trans-retinol
6
TeriparatidePhase 313052232-67-416133850
Synonyms:
52232-67-4
D06078
Forteo
Forteo (TN)
 
TERIPARATIDE
Teriparatide (USAN/INN)
Teriparatide (genetical recombination)
Teriparatide (genetical recombination) (JAN)
Teriparatide recombinant human
7FluoridesPhase 2405
8CalcifediolPhase 1, Phase 24019356-17-3
9
SomatostatinPhase 2, Phase 021238916-34-6, 51110-01-153481605
Synonyms:
growth hormone-inhibiting hormone (GHIH)
 
somatotropin release-inhibiting factor (SRIF)
somatotropin release-inhibiting hormone
10
Nitroprusside5815078-28-111963622
Synonyms:
13755-38-9 (di-hydrochloride salt, diH20)
14402-89-2 (di-hydrochloride salt)
15078-28-1
C07269
CHEMBL74115
CID11953891
Disodium nitroprusside dihydrate
LS-187044
Nipride
 
Nitroferricyanide
Nitropress
Nitroprusside
Pentacyanidonitrosylferrate(2-)
Sodium Nitroprusside
Sodium nitroferricyanide dihydrate
Sodium nitroprusside dihydrate
Sodium nitroprusside extra pure
UNII-169D1260KM
[Fe(CN)5(NO)](2-)
nitroferricyanide
11
Iron10807439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
12
Acetylcholine75251-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
13glucocorticoids4756
14
MentholPhase 021842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
15
Cimetidine6951481-61-92756
Synonyms:
1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine
1-Cyano-2-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]guanidine
1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine
2-Cyano-1-methyl-3-[2-(5-methyl-1H-imidazol-4-yl-methylthio)ethyl]guanidine
2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
2984-61-4
51481-61-9
AC-12795
AC1L1EE8
AC1Q3XK6
Acibilin
Acinil
Altramet
Ambap2984-61-4
BPBio1_000101
BRD-K18618618-001-01-6
BRD-K34157611-001-04-6
BSPBio_000091
BSPBio_002978
Bio-0395
Biomet400
Brumetidina
C 4522
C10H16N6S
C4522_SIGMA
CCRIS 3247
CHEBI:101620
CHEBI:3699
CHEMBL30
CID2756
CIMETIDINE A/AB
CPD001370748
Ci metum
Cimal
Cimetadine
Cimetag
Cimetidin
Cimetidina
Cimetidina [INN-Spanish]
Cimetidine (JP15/USP/INN)
Cimetidine Hcl
Cimetidine [USAN:INN:BAN:JAN]
Cimetidinum
Cimetidinum [INN-Latin]
Cimetum
Cimétidine
D00295
DB00501
DRG-0150
DivK1c_000166
Dyspamet
EINECS 257-232-2
EU-0100293
Edalene
Eureceptor
Evicer
FPF 1002
Gastrobitan
Gastromet
HMS1921C14
HMS2089O03
HMS2092I14
HMS500I08
HSDB 3917
Histodil
I14-0371
IDI1_000166
KBio1_000166
KBio2_000975
KBio2_003543
KBio2_006111
KBio3_002198
KBioGR_001323
KBioSS_000975
L000186
L003827
L013434
LS-7278
LS-73445
LS-73446
 
Lopac-C-4522
Lopac0_000293
MLS000069791
MLS001148596
MLS002153265
MLS002154178
Magicul
Metracin
MolPort-001-838-193
MolPort-002-542-886
MolPort-003-895-998
N''-Cyano-N-methyl-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine
N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)-ethyl)guanidine
N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
N''-cyano-N-methyl-n'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
N-Cyano-N'-Methyl-N''-(2-(((5-Methyl-1H-Imidazol-4-YL)Methyl)Thio)Ethyl) Guanidine
N-Cyano-N'-methyl-N''-(2-(((5-methyl-1 H-imidazol-4-yl) methyl)thio)ethyl)guanidine
N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
N-Cyano-N'-methyl-[2-[[[5-methyl-1H-imidazol-4-yl]methyl]thio]ethyl]guanidine
N-Cyano-n'-methyl-n''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine
N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine
N-cyano-N'-methyl-N''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
NCGC00015240-01
NCGC00015240-03
NCGC00024859-01
NCGC00024859-02
NCGC00024859-03
NCGC00024859-04
NCGC00024859-05
NCGC00091439-01
NCGC00091439-02
NCGC00091439-03
NCGC00091439-04
NCGC00185989-01
NCI60_002936
NINDS_000166
NSC335308
Peptol
Prestwick3_000026
Prestwick_65
S1845_Selleck
SAM002554892
SBB057794
SK&F-92334
SKF 92334
SKF-92334
SMR000038895
SPBio_000884
SPECTRUM1500684
STK528249
Sigmetadine
Spectrum2_000782
Spectrum3_001389
Spectrum4_000812
Spectrum5_001541
Spectrum_000495
TL8003410
Tagamet
Tagamet (TN)
Tagamet Hb
Tagamet Hb 200
Tagamet hb 200
Tagamet, SKF-92334, Tratul, Tametin, Dyspamet, Acinil, Cimetidine
Tametin
Tocris-0902
Tratul
UPCMLD-DP029
UPCMLD-DP029:001
Ulcedin
Ulcedine
Ulcerfen
Ulcestop
Ulcimet
Ulcofalk
Ulcomedina
Ulcomet
Ulhys
Valmagen
Venopex
ZINC18115268
ZINC18207290
cimetidine
nchembio732-comp5
16phenylalanineNutraceuticalPhase 0155

Interventional clinical trials:

(show all 45)
idNameStatusNCT IDPhase
1Vitamin D Status in Males in Jerusalem Area and Its Correlation to Parathyroid Hormone (PTH) Level and Bone Mineral DensityCompletedNCT01025128Phase 4
2Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in JapanCompletedNCT02531867Phase 4
3A Single Wintertime Dose of Vitamin D3 to Prevent Winter Decline in Vitamin D Status in Healthy AdultsCompletedNCT01924910Phase 4
4Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.RecruitingNCT02238418Phase 4
5A Pilot Study to Evaluate the Effect of Forsteo (Teriparatide, 1-34-rh-PTH) in Anorexia Nervosa Patients With Low Bone Mineral Density and Increased Bone Fagility (FAN-Trial)RecruitingNCT01801397Phase 3
6Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02537431Phase 3
7Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)Active, not recruitingNCT01176266Phase 2, Phase 3
8Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)CompletedNCT00952484Phase 2
9Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)CompletedNCT01163149Phase 2
10Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)CompletedNCT01205152Phase 2
11Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)CompletedNCT01203826Phase 2
12Nursing-Home Residents Given Bread Fortified With Vitamin D3CompletedNCT00789503Phase 1, Phase 2
13Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)CompletedNCT00744042Phase 1, Phase 2
14Combination Osteogenic Therapy in Established OsteoporosisCompletedNCT00018447Phase 2
15Evaluation of 68Gallium-DOTATATE PET/CT for Detecting Neuroendocrine TumorsRecruitingNCT01967537Phase 2
16Study of KRN23 in Adult Subjects With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS)Active, not recruitingNCT02304367Phase 2
17A Study of KRN23 in Subjects With Tumor-Induced Osteomalacia or Epidermal Nevus SyndromeNot yet recruitingNCT02722798Phase 2
18Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)WithdrawnNCT00894075Phase 2
19A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/OsteomalaciaCompletedNCT02181764Phase 1
20Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)CompletedNCT00739505Phase 1
21Cinacalcet for Fibroblast Growth Factor 23 (FGF23)-Mediated Hypophosphatemia (Hypophosphatemic Rickets)TerminatedNCT01748812Phase 1
22Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)Approved for marketingNCT02496689
23Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic OsteomalaciaCompletedNCT00099762
24Serum FGF-23 and Vitamin D DeficiencyCompletedNCT01102751
25Maternal and Infant Vitamin Status During the First Nine Months of Infant LifeCompletedNCT02548520
26Non-interventional Substudy of ALX-HPP-502 to Assess Natural History of Patients With Juvenile-onset HPP Who Served as Historical Controls in ENB-006-09CompletedNCT02235493
27Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)CompletedNCT02104219
28Serum Sclerostin Level & Treatment of Vitamin D DeficiencyCompletedNCT01553344
29A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)CompletedNCT01419028
30Pilot Pharmacokinetic Study of Daily Versus Monthly High-Dose Cholecalciferol SupplementationCompletedNCT01079923
31APOSTrophe Study (Parenteral Nutrition and Bone Trophicity) Impact of a Long-term Parenteral Nutrition on Bone Metabolism Measured by High Resolution Peripheral Quantitative Computer Tomography (HR-pQCT) in Children and Young AdultsCompletedNCT02368496
32The Effect of Vitamin D Repletion on Small Low Density Lipoprotein (LDL) Particle Number in Subjects at Elevated Cardiovascular RiskCompletedNCT01008384
33Replacement of Vitamin D in Patients With Active TuberculosisCompletedNCT01130311
3468Ga-DOTATATE PET/CT in Oncogenic OsteomalaciaRecruitingNCT01524016Phase 0
35Molecular Pathways Involved in the Pathogenesis and Behavior of Mesenchymal Phosphaturic Tumors Causing Oncogenic OsteomalaciaRecruitingNCT02331966
36Observing the Changes of Fibroblast Growth Factor 23 in Patients of Tumor Induced OsteomalaciaRecruitingNCT01660308
37Evaluation and Treatment of Skeletal DiseasesRecruitingNCT00024804
38Study of the Diagnostic Value of Stable Calcium Isotope Profiling in Bone and Calcium DisordersRecruitingNCT02252679
39Vitamin D, Bones, Nutritional and Cardiovascular StatusRecruitingNCT01832623
40The Impact of Severe Vitamin D Deficiency and Its Correction on Bone Mineral Density (BMD) in Postmenopausal WomenRecruitingNCT01694355
41Natural History Study of Patients With Hypophosphatasia (HPP)RecruitingNCT02237625
42Does Intravenous Iron Therapy Decrease Serum Phosphorous Levels?RecruitingNCT02420119
43COMPREHENSIVE® REVERSE SHOULDER Mini BasePlateActive, not recruitingNCT02084693
44Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman SpectroscopyEnrolling by invitationNCT02814591
45Hypovitaminosis D Prediction ScoreNot yet recruitingNCT02822651

Search NIH Clinical Center for Osteomalacia

Genetic Tests for Osteomalacia

About this section

Anatomical Context for Osteomalacia

About this section

MalaCards organs/tissues related to Osteomalacia:

34
Bone, Kidney, Testes, Liver, Prostate, Brain, Thyroid

FMA organs/tissues related to Osteomalacia:

17
Bone

Animal Models for Osteomalacia or affiliated genes

About this section

MGI Mouse Phenotypes related to Osteomalacia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.1ALPL, DMP1, PHEX, PTH, VDR
2MP:00053678.2CASR, CYP24A1, DMP1, FGF23, PHEX, VDR
3MP:00053718.1ALPL, DMP1, FGF23, PHEX, PTH, VDR
4MP:00053787.3ALPL, CASR, CYP24A1, DMP1, FGF23, PHEX
5MP:00053877.3ALPL, CASR, DMP1, FGF23, MEPE, PHEX
6MP:00053977.2ALPL, CASR, DMP1, FGF23, MEPE, PHEX
7MP:00053766.7ALPL, CASR, CYP24A1, DMP1, FGF23, NR1I2
8MP:00053906.5ALPL, CASR, CYP24A1, DMP1, FGF23, MEPE

Publications for Osteomalacia

About this section

Articles related to Osteomalacia:

(show top 50)    (show all 665)
idTitleAuthorsYear
1
177Lu-DOTATATE PRRT as promising new treatment approach in Recurrent Skull Base Phosphaturic Mesenchymal Tumor causing paraneoplastic oncogenic osteomalacia: a potential therapeutic application of PRRT beyond NET. (27634982)
2016
2
Needle(s) in the Haystack-Synchronous Multifocal Tumor-Induced Osteomalacia. (26691889)
2016
3
Symptomatic hypophosphataemic osteomalacia secondary to the treatment with iron carboxymaltose detected in bone scintigraphy. (27246291)
2016
4
(68)Ga-DOTATATE for Tumor Localization in Tumor-induced Osteomalacia. (27533306)
2016
5
Oncogenic osteomalacia presenting as a crippling illness in a young man. (25263679)
2014
6
Periodontitis associated with osteomalacia. (25425827)
2014
7
Clinical usefulness of the determination of fibroblast growth factor 23 in the evaluation of patients with osteomalacia]. (24629692)
2014
8
Osteomalacia and myelofibrosis as a manifestation of vitamin D deficiency. (25025008)
2014
9
Tumor localization and biochemical response to cure in tumor-induced osteomalacia. (23362135)
2013
10
Radiologic case study. Osteomalacia. (23127434)
2012
11
Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report. (22906214)
2012
12
Intracranial phosphaturic mesenchymal tumor, mixed connective tissue variant presenting without oncogenic osteomalacia. (23372968)
2012
13
Osteomalacia in a patient with Paget's bone disease treated with long-term etidronate. (23022200)
2012
14
'Tumour-induced osteomalacia'. (22736784)
2012
15
The importance of cone beam CT in the radiological detection of osteomalacia. (22074877)
2012
16
Oncogenic osteomalacia due to phosphaturic mesenchymal tumor of the craniofacial sinuses. (22461817)
2011
17
Severe hypophosphatemic osteomalacia with Fanconi syndrome, renal tubular acidosis, vitamin D deficiency and primary biliary cirrhosis. (19252361)
2009
18
Bone pain due to fractures revealing osteomalacia related to tenofovir-induced proximal renal tubular dysfunction in a human immunodeficiency virus-infected patient. (19265350)
2009
19
Tumor-induced osteomalacia: a case report. (19578602)
2009
20
Disabling osteomalacia and myopathy as the only presenting features of celiac disease: a case report. (19128487)
2009
21
Tumor-induced osteomalacia. (20228870)
2009
22
Renal phosphate wasting due to tumor-induced osteomalacia: a frequently delayed diagnosis. (18668025)
2009
23
Tumor-induced osteomalacia: a case of diagnostic dilemma. (17667438)
2007
24
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia. (16207822)
2006
25
Oncogenic osteomalacia: muscular weakness and multiple fractures. (16864847)
2006
26
Polymorphisms at the ligand binding site of the vitamin D receptor gene and osteomalacia. (16403954)
2005
27
Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice. (15920156)
2005
28
Case 3. Oncogenic osteomalacia associated with hemangiopericytoma localized by octreotide scan. (15908675)
2005
29
Osteomalacia after Roux-en-Y gastric bypass. (15310536)
2004
30
Oncogenic osteomalacia--a complex dance of factors. (12711747)
2003
31
FGF-23 on hypophosphatemic rickets/osteomalacia]. (15775350)
2002
32
Lesson of the week: Danger of stereotyping in suspected osteomalacia. (11463688)
2001
33
Pentavalent technetium-99m DMSA uptake in pseudofractures of osteomalacia. (11139060)
2001
34
Diagnosis of a patient with oncogenic osteomalacia using a phosphate uptake bioassay of serum and magnetic resonance imaging. (11581007)
2001
35
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia. (10945470)
2000
36
Osteomalacia associated with carbamazepine/valproate. (10676838)
2000
37
Acquired osteomalacia. (9174801)
1997
38
The PEX gene: its role in X-linked rickets, osteomalacia, and bone mineral metabolism. (9386970)
1997
39
Osteomalacia and osteoporosis in a woman with ankylosing spondylitis. (9157786)
1996
40
Coexisting hyperthyroidism and primary hyperparathyroidism with vitamin D-deficient osteomalacia in a Vietnamese immigrant. (15251523)
1996
41
Osteomalacia with hypophosphatemia and hypercalciuria: a possible new variant of osteomalacia. (7608793)
1995
42
Hypophosphatemic osteomalacia with plantar neurilemoma. A review of the literature (100 cases). (7552213)
1995
43
Oncogenic osteomalacia: evidence for a humoral phosphaturic factor. (7745010)
1995
44
Oncogenic osteomalacia: imaging studies. (8387360)
1993
45
A neuroendocrine cause of oncogenic osteomalacia. (1378890)
1992
46
Osteomalacia secondary to renal tubular acidosis in a patient with primary SjAPgren's syndrome. (1764843)
1991
47
Oncogenic osteomalacia. (6469602)
1984
48
Neurogenic muscle atrophy and osteomalacia in adult Fanconi syndrome. (889295)
1977
49
Acquired vitamin D-resistant osteomalacia: a new variety characterized by hypercalcemia, low serum bicarbonate and hyperglycinuria. (13906479)
1962
50
Osteoporosis, osteomalacia and osteitis fibrosa cystica, with special reference to the parathyroid and calcium metabolism. (14885642)
1951

Variations for Osteomalacia

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Expression for genes affiliated with Osteomalacia

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Search GEO for disease gene expression data for Osteomalacia.

Pathways for genes affiliated with Osteomalacia

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GO Terms for genes affiliated with Osteomalacia

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Biological processes related to Osteomalacia according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1cellular response to vitamin DGO:007130510.4BGLAP, FGF23
2bone mineralizationGO:003028210.1BGLAP, PHEX
3positive regulation of vitamin D 24-hydroxylase activityGO:001098010.1FGF23, VDR
4regulation of bone mineralizationGO:003050010.1BGLAP, FGF23
5positive regulation of ossificationGO:004577810.1CALCA, PTH
6vitamin D catabolic processGO:004236910.0CYP24A1, FGF23
7vitamin D metabolic processGO:004235910.0CYP24A1, FGF23
8vitamin D receptor signaling pathwayGO:007056110.0CYP24A1, VDR
9negative regulation of bone mineralizationGO:00305029.9FGF23, MEPE
10osteoblast differentiationGO:00016499.6ALPL, BGLAP, CYP24A1
11biomineral tissue developmentGO:00312149.5DMP1, MEPE
12ossificationGO:00015039.3BGLAP, CASR, DMP1
13response to vitamin DGO:00332809.1ALPL, BGLAP, CYP24A1, PTH
14cellular calcium ion homeostasisGO:00068748.5CALCA, CASR, PTH, VDR
15skeletal system developmentGO:00015017.9ALPL, BGLAP, MEPE, PHEX, PTH, VDR

Molecular functions related to Osteomalacia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingGO:00048799.6NR1I2, VDR

Sources for Osteomalacia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet