MCID: OTT001
MIFTS: 31

Otitis Externa malady

Ear category

Summaries for Otitis Externa

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 An external ear disease that involves inflammation of the outer ear and ear canal. it can be caused by active bacterial or fungal infection.

MalaCards: Otitis Externa, also known as acute infective otitis externa, is related to malignant otitis externa and chronic fungal otitis externa. An important gene associated with Otitis Externa is ELANE (elastase, neutrophil expressed).

Wikipedia:64 Otitis externa (also known as \"external otitis\" and \"Swimmer\'s ear\") is an inflammation of the... more...

Aliases & Classifications for Otitis Externa

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 27ICD9CM, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear


Aliases & Descriptions:

otitis externa 8 10
acute infective otitis externa 61
infective otitis externa 61
swimmer's ear 8


External Ids:

Disease Ontology8 DOID:9463
ICD9CM27 380.10, 380.1
NCIt40 C3299
ICD1025 H60, H60.2, H62.4

Related Diseases for Otitis Externa

Sources:
17GeneCards, 18GeneDecks
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Diseases in the Otitis Externa family:

malignant otitis externa

Diseases related to Otitis Externa via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1malignant otitis externa11.1
2chronic fungal otitis externa10.5
3beach ear10.3
4acute leukemia10.3
5allergic contact dermatitis10.3
6squamous cell carcinoma10.3
7suppurative otitis media10.3
8cholesteatoma of external ear10.2
9bone carcinoma10.2
10sensorineural hearing loss10.2
11lemierre's syndrome10.2
12acute infection of pinna10.2
13ecthyma10.2
14tonsillitis10.2
15septic arthritis10.2
16multiple cranial nerve palsy10.2
17n syndrome10.2
18adenocarcinoma10.2
19adenoma10.2
20arthritis10.2
21tuberculosis10.2
22candida glabrata10.2
23demodicidosis10.2
24myoclonus10.2
25ramsay-hunt syndrome10.2

Graphical network of the top 20 diseases related to Otitis Externa:



Diseases related to otitis externa

Clinical Features for Otitis Externa

Drugs & Therapeutics for Otitis Externa

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Otitis Externa

Drug clinical trials:

Search ClinicalTrials for Otitis Externa

Search NIH Clinical Center for Otitis Externa

Search CenterWatch for Otitis Externa

Genetic Tests for Otitis Externa

Anatomical Context for Otitis Externa

Animal Models for Otitis Externa or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Otitis Externa

Sources:
51PubMed
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Articles related to Otitis Externa:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
What are the criteria for terminating treatment for necrotizing (malignant) otitis externa? (24105671)
2013
2
Concurrent necrotising otitis externa and adenocarcinoma of the temporal bone: a diagnostic challenge. (24197806)
2013
3
Single photon emission computed tomography/computed tomography for malignant otitis externa: lesion not shown on planar image. (23313120)
2013
4
Water related otitis externa. (23213950)
2012
5
Arcanobacterium canis sp. nov., isolated from otitis externa of a dog, and emended description of the genus Arcanobacterium Collins et al. 1983 emend. Yassin et al. 2011. (22081713)
2012
6
Outcomes of canalplasty for chronic obliterative otitis externa. (22892176)
2012
7
A meta-analysis of the efficacy of quinolone containing otics in comparison to antibiotic-steroid combination drugs in the local treatment of otitis externa. (21919557)
2011
8
Treatment of canine otitis externa using video otoscopy. (21597241)
2011
9
Skull based osteomyelitis due to postsurgery malignant otitis externa presenting as stroke. (22696765)
2011
10
Audit of otitis externa referrals and management in a tertiary care setting. (21777546)
2011
11
In vitro antimicrobial resistance of Pseudomonas aeruginosa isolated from canine otitis externa in Rio de Janeiro, Brazil. (24031774)
2011
12
Total ear canal ablation and lateral bulla osteotomy for treatment of otitis externa and media in a rabbit. (21756179)
2011
13
Extracts from The Cochrane Library: Interventions for acute otitis externa. (20620612)
2010
14
Necrotizing otitis externa: 19 cases' report. (20058154)
2010
15
Malignant otitis externa: case series. (20388240)
2010
16
Reproducibility of ear cytology in dogs with otitis externa. (20605955)
2010
17
Malignant otitis externa with ecthyma gangrenosum and pneumonia in an infant. (20128265)
2009
18
Prognostic scoring in necrotising otitis externa. (19586581)
2009
19
A single topical agent is clinically equivalent to the combination of topical and oral antibiotic treatment for otitis externa. (18598837)
2008
20
Comparison of efficacy and safety of ciprofloxacin otic solution 0.2% versus polymyxin B-neomycin-hydrocortisone in the treatment of acute diffuse otitis externa*. (19032135)
2008
21
Bilateral hipoglossal nerve palsy in necrotizing otitis externa. (17923934)
2007
22
Identification and antimicrobial susceptibility of bacteria and yeasts isolated from healthy dogs and dogs with otitis externa. (18045339)
2007
23
Spontaneous cerebrospinal fluid otorrhoea presenting as otitis externa. (17252280)
2007
24
Otitis externa. (18076432)
2007
25
Sensitivity and spectrum of bacterial isolates in infectious otitis externa. (15353150)
2004
26
Evolution of management approaches for otitis externa. (12690268)
2003
27
Ulcerative otitis externa responsive to immunosuppressive therapy in two dogs. (12201444)
2002
28
Malignant otitis externa--a high index of suspicion is still needed for diagnosis. (11928781)
2002
29
Antimicrobial susceptibility of staphylococci isolated from otitis externa in dogs. (10886613)
2000
30
Osteomyelitis of the temporomandibular joint in patients with malignant otitis externa. (10505160)
1999
31
The relation of patient satisfaction with treatment of otitis externa to clinical outcomes: development of an instrument. (10440629)
1999
32
Microbiology of otitis externa. (9018252)
1997
33
Antimicrobial sensitivity in microorganisms isolated from canine otitis externa. (9283285)
1997
34
Otitis externa: management of the recalcitrant case. (8579150)
1994
35
Otitis externa malignum. (1919653)
1991
36
Squamous cell carcinoma of the ear masquerading as malignant otitis externa. (1927594)
1991
37
Management of radiation-induced otitis externa. (2376703)
1990
38
Successful treatment of malignant otitis externa with oral ciprofloxacin. (2745992)
1989
39
Surgical management of otitis externa. (3264957)
1988
40
Actinomycotic otitis externa. (4064980)
1985
41
Treatment of otitis externa with miconazole nitrate. A comparative study involving 85 cases. (6342163)
1983
42
Moxalactam therapy. Its use in chronic suppurative otitis media and malignant external otitis. (6212042)
1982
43
Necrotising otitis externa and diabetic control. (6121256)
1982
44
Incidence of otitis externa in dogs and cats in Japan. (7027593)
1981
45
When the patient has otitis externa. (7364220)
1980
46
The therapy of otitis externa. (373160)
1979
47
Canine otitis externa caused by the fungus Sporothrix schenkii. (638939)
1978
48
Malignant otitis externa. (701981)
1978
49
A simple surgical procedure to improve drainage and ventilation in the treatment of chronic otitis externa in dogs. (250994)
1978
50
Intractable Forms of Dermatitis of the External Ear in cases of Chronic Suppurative Otitis Media. (19985594)
1927

Genetic Variations for Otitis Externa

Expression for genes affiliated with Otitis Externa

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Otitis Externa

Search GEO for disease gene expression data for Otitis Externa.

Pathways for genes affiliated with Otitis Externa

Compounds for genes affiliated with Otitis Externa

GO Terms for genes affiliated with Otitis Externa

Sources:
16Gene Ontology
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Cellular components related to Otitis Externa according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.9ELANE, NXPH4, TUB

Biological processes related to Otitis Externa according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phagocytosisGO:0069099.5ELANE, TUB

Products for genes affiliated with Otitis Externa

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Sources for Otitis Externa

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet