MCID: OTT001
MIFTS: 38

Otitis Externa malady

Ear diseases category
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Summaries for Otitis Externa

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Sources:
8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 An external ear disease that involves inflammation of the outer ear and ear canal. it can be caused by active bacterial or fungal infection.

MalaCards: Otitis Externa, also known as acute infective otitis externa, is related to malignant otitis externa and otitis media. An important gene associated with Otitis Externa is ELANE (elastase, neutrophil expressed). Affiliated tissues include skin, bone and brain, and related mouse phenotype homeostasis/metabolism.

Wikipedia:65 Otitis externa (also known as external otitis and swimmer\'s ear) is an inflammation of the outer ear... more...

Aliases & Classifications for Otitis Externa

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 40NCIt, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

otitis externa 8 10
acute infective otitis externa 62
infective otitis externa 62
swimmer's ear 8


External Ids:

Disease Ontology8 DOID:9463
NCIt40 C3299
ICD9CM27 380.10, 380.1
ICD1025 H60, H60.2, H62.4

Related Diseases for Otitis Externa

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Otitis Externa:



Diseases related to otitis externa

Symptoms for Otitis Externa

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Drugs & Therapeutics for Otitis Externa

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Otitis Externa

Genetic Tests for Otitis Externa

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Anatomical Context for Otitis Externa

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Sources:
33MalaCards
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MalaCards organs/tissues related to Otitis Externa:

33
Skin, Bone, Brain, Testes, Tonsil

Animal Models for Otitis Externa or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Otitis Externa:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053769.1ELANE, NXPH4

Publications for Otitis Externa

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Sources:
52PubMed
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Articles related to Otitis Externa:

(show top 50)    (show all 485)
idTitleAuthorsYear
1
Necrotizing otitis externa: a systematic review. (23598690)
2013
2
What are the criteria for terminating treatment for necrotizing (malignant) otitis externa? (24105671)
2013
3
A case of orbital apex syndrome in a patient with malignant otitis externa. (23894912)
2013
4
Proliferative and necrotising otitis externa in a cat without pinnal involvement: video-otoscopic features. (23197497)
2013
5
Use of a hearing loss grading system and an owner-based hearing questionnaire to assess hearing loss in pet dogs with chronic otitis externa or otitis media. (23829225)
2013
6
The modified Merocel(Ar) pope ear wick in severe acute otitis externa management. (22433153)
2012
7
Acute bacterial otitis externa: efficacy and safety of topical treatment with an antibiotic ear drop formulation in comparison to glycerol treatment. (21332272)
2011
8
Comparison of steroid antibiotic pack and 10% ichthammol glycerine pack in relieving pain of acute otitis externa in children. (21292332)
2011
9
A meta-analysis of the efficacy of quinolone containing otics in comparison to antibiotic-steroid combination drugs in the local treatment of otitis externa. (21919557)
2011
10
Otitis externa. (21418684)
2010
11
A double-blind randomised clinical trial of the treatment of otitis externa using topical steroid alone versus topical steroid-antibiotic therapy. (18560873)
2009
12
Chronic recurrent otitis externa secondary to allergic contact dermatitis to nickel and phosphorus sesquisulfide. (19706056)
2009
13
In vitro evaluation of the synergistic activity of neomycin-polymyxin B association against pathogens responsible for otitis externa. (19505383)
2009
14
A single topical agent is clinically equivalent to the combination of topical and oral antibiotic treatment for otitis externa. (18598837)
2008
15
Otitis externa: the analysis of relationship between particular signs/symptoms and species and genera of identified microorganisms. (18664104)
2008
16
Dexamethasone phosphate in antibiotic ear drops for the treatment of acute bacterial otitis externa. (18606053)
2008
17
In vitro antimicrobial activity of the leaf extract of Harungana madagascariensis Lam. Ex Poir. (Hypericaceae) against strains causing otitis externa in dogs and cats. (17385560)
2007
18
In vitro activity of an ear rinse containing tromethamine, EDTA, benzyl alcohol and 0.1% ketoconazole on Malassezia organisms from dogs with otitis externa. (17355426)
2007
19
Pooled analysis of two clinical trials comparing the clinical outcomes of topical ciprofloxacin/dexamethasone otic suspension and polymyxin B/neomycin/hydrocortisone otic suspension for the treatment of acute otitis externa in adults and children. (18035194)
2007
20
Resistance of Pseudomonas to ciprofloxacin: implications for the treatment of malignant otitis externa. (16995959)
2007
21
Bilateral hipoglossal nerve palsy in necrotizing otitis externa. (17923934)
2007
22
Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa. (15846724)
2005
23
A comparative study of two antimicrobial/anti-inflammatory formulations in the treatment of canine otitis externa. (16238809)
2005
24
External auditory canal pH in chronic otitis externa. (12871245)
2003
25
Allergic contact otitis externa due to iodoform in BIPP cavity dressings. (12190629)
2002
26
Development of resistant bacteria isolated from dogs with otitis externa or urinary tract infections after exposure to enrofloxacin in vitro. (12584687)
2002
27
Spinose ear tick, Otobius megnini (DugA"s, 1884) as the cause of an incident of painful otitis externa in humans. (11811697)
2001
28
Improving standards in the treatment of acute otitis externa by the use of a treatment protocol and open access to aural toilet. (11320843)
2001
29
Antimicrobial susceptibility of staphylococci isolated from otitis externa in dogs. (10886613)
2000
30
Optimum incubation conditions for the isolation of yeasts from canine otitis externa. (11075548)
2000
31
Oral steroids in the treatment of otitis externa. (10495523)
1999
32
Necrotizing otitis externa, otitis media, peripheral facial paralysis, and brain abscess in a thalassemic child after allogeneic BMT. (9783316)
1998
33
Otitis externa--the clinical pattern in a tertiary institution in Singapore. (9663313)
1998
34
Malignant otitis externa with optic neuritis. (9624378)
1998
35
Microbiology of otitis externa. (9018252)
1997
36
Antimicrobial sensitivity in microorganisms isolated from canine otitis externa. (9283285)
1997
37
Occupational otitis externa in chicken catchers. (9176622)
1997
38
Otitis externa. (8893215)
1996
39
Antimicrobial susceptibility and rRNA gene restriction patterns among Staphylococcus intermedius from healthy dogs and from dogs suffering from pyoderma or otitis externa. (7502950)
1995
40
Bone-anchored hearing aids in patients with sensorineural hearing loss and persistent otitis externa. (7788931)
1995
41
Management of otitis externa. (7817494)
1994
42
The efficacy of oral cotrimoxazole in the treatment of otitis externa in general practice. (7683742)
1993
43
Otitis externa: clinical comparison of local ciprofloxacin versus local oxytetracycline, polymyxin B, hydrocortisone combination treatment. (8222746)
1993
44
Fatal necrotizing otitis externa in a patient with AIDS. (1775861)
1991
45
Chronic otitis externa and otitis media treated by total ear canal ablation and ventral bulla osteotomy in thirteen dogs. (2333689)
1990
46
Discharge from the ear: otitis externa and acute otitis media. (7448539)
1980
47
The therapy of otitis externa. (373160)
1979
48
A clinical study of otitis externa in the dog. (858120)
1977
49
Necrotizing otitis externa. (894127)
1977
50
Otitis externa due to Pseudomonas in swimming pool bathers. (408486)
1977

Variations for Otitis Externa

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Expression for genes affiliated with Otitis Externa

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Otitis Externa

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Pathways for genes affiliated with Otitis Externa

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Compounds for genes affiliated with Otitis Externa

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GO Terms for genes affiliated with Otitis Externa

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16Gene Ontology
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Cellular components related to Otitis Externa according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1ELANE, NXPH4

Products for genes affiliated with Otitis Externa

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  • Antibodies
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  • Lysates
  • Antibodies

Sources for Otitis Externa

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet