MCID: OTM001
MIFTS: 22

Otomycosis malady

Ear diseases category

Summaries for Otomycosis

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Sources:
9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 A otitis externa which is a disease of the ear produced by the growth of fungi in the external auditory canal. it is characterized by inflammation, pruritus, scaling and severe discomfort. the most common fungi are aspergillus niger and candida albicans.

MalaCards: Otomycosis, also known as singapore ear, is related to chronic fungal otitis externa and coccidioidomycosis. An important gene associated with Otomycosis is CALM3 (calmodulin 3 (phosphorylase kinase, delta)), and among its related pathways are Immune response IFN gamma signaling pathway and Glycogen Metabolism.

Wikipedia:66 Otomycosis (also known as Singapore Ear) is a fungal ear infection, a superficial mycotic infection of... more...

Aliases & Classifications for Otomycosis

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

otomycosis 9 11 63
singapore ear 9


External Ids:

Disease Ontology9 DOID:0050147

Related Diseases for Otomycosis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Otomycosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1chronic fungal otitis externa10.0
2coccidioidomycosis10.0
3middle ear disease10.0
4otitis externa10.0
5pseudoachondroplasia9.9CALM1, CALM3, CALM2
6malignant hyperthermia9.9CALM1, CALM3, CALM2
7pertussis9.9CALM2, CALM3, CALM1
8vascular disease9.9CALM1, CALM3, CALM2
9toxic encephalopathy9.9CALM1, CALM3, CALM2
10cholera9.9CALM2, CALM3, CALM1

Graphical network of diseases related to Otomycosis:



Diseases related to otomycosis

Symptoms for Otomycosis

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Drugs & Therapeutics for Otomycosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Otomycosis

Drug clinical trials:

Search ClinicalTrials for Otomycosis

Search NIH Clinical Center for Otomycosis

Search CenterWatch for Otomycosis

Genetic Tests for Otomycosis

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Anatomical Context for Otomycosis

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Animal Models for Otomycosis or affiliated genes

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Publications for Otomycosis

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Sources:
53PubMed
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Articles related to Otomycosis:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Otomycosis in Shanghai: aetiology, clinical features and therapy. (21999222)
2012
2
Species assignment and antifungal susceptibilities of black aspergilli recovered from otomycosis cases in Iran. (21895787)
2012
3
Otomycosis due to filamentous fungi. (21499908)
2011
4
Antibiotic resistance and otomycosis in the draining ear: culture results by diagnosis. (21041003)
2011
5
Chronic monolateral otomycosis in a dog caused by Aspergillus ochraceus. (20409075)
2010
6
Otomycosis due to Aspergillus spp. in a dog: case report and literature review. (20492628)
2010
7
Chronic otomycosis due to malassezia spp. (20606976)
2010
8
Otomycosis: a retrospective study. (19649486)
2009
9
Aspergillus otomycosis in an immunocompromised patient. (19006061)
2008
10
Ototopical antifungals and otomycosis: a review. (18279975)
2008
11
Scedosporium apiospermum otomycosis. (17606042)
2007
12
Suction clearance and 2% topical miconazole versus the same combination with acidic drops in the treatment of otomycosis. (17883017)
2007
13
Otomycosis: subdermal growth in calcified mass. (16799802)
2006
14
A case of otomycosis caused by Aspergillus sclerotiorum. (15729874)
2004
15
Chronic bilateral otomycosis caused by Aspergillus niger. (14998406)
2004
16
Concomitant otomycosis and dermatomycoses: a clinical and microbiological study. (12520352)
2003
17
Otomycosis in Turkey: predisposing factors, aetiology and therapy. (12590854)
2003
18
Otomycosis. (12092275)
2002
19
Treatment outcome of otomycosis in Ilorin, Nigeria. (12081339)
2002
20
Otomycosis with pus. (12149832)
2002
21
Randomized prospective comparative study: short-term treatment with ciclopiroxolamine (cream and solution) versus boric acid in the treatment of otomycosis. (12572722)
2002
22
In vitro evaluation of sulfadrugs against fungi causing otomycosis. (15061593)
2002
23
The fungal profile of otomycosis patients in Ilorin, Nigeria. (11806011)
2001
24
Otomycosis: a clinicomycologic study. (10969470)
2000
25
Otomycosis: the detection of fungi in ears by immunofluorescence microscopy. (9222637)
1997
26
Otomycosis--a clinico-mycological study and efficacy of mercurochrome in its treatment. (9008878)
1996
27
Calcium oxalate crystal deposition in necrotizing otomycosis caused by Aspergillus niger. (8415598)
1993
28
Antimycotic effect of fixed oils treated with herbal seeds on the growth of fungi causing otomycosis. (22556643)
1993
29
Sporostatic effect of some oils against fungi causing otomycosis. (1452224)
1992
30
A microbiological study of otomycosis in Visakhapatnam. (3429879)
1987
31
Broad spectrum antifungal agents in otomycosis. (3746101)
1986
32
Otomycosis: an experimental evaluation of six antimycotic agents. (6461705)
1982
33
"How I do it"--otology and neurotology. A specific issue and its solution. Merthiolate in treatment of otomycosis. (7242211)
1981
34
Topical 5-fluorocytosine therapy in otomycosis. (4595093)
1974
35
Studies on experimental otomycosis in dogs. (4783390)
1973
36
Otomycosis due to Aspergillus niger. (5473595)
1970
37
Otomycosis: an entity. (4224861)
1967
38
Otomycosis: a clinical entity--clinical and experimental study. (6050987)
1967
39
Tropical otomycosis. (6050986)
1967
40
Otomycosis: an entity, not a myth. (6071123)
1967
41
THE MYTH OF OTOMYCOSIS. (14233233)
1965
42
Otomycosis. (13241530)
1955
43
Etiology of otomycosis; bacterial flora of the ear. (15433689)
1950
44
Relation of various fungi to otomycosis. (20265711)
1947
45
Otomycosis; some remarks concerning its diagnosis and treatment. (20996337)
1946
46
Pathogenicity of the aspergilli of otomycosis. (20999058)
1946
47
Etiology of otomycosis. (20999806)
1946
48
Otomycosis. (21025558)
1946
49
Management of otomycosis. (21004521)
1945
50
Case of Otomycosis. (19985146)
1926

Variations for Otomycosis

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Expression for genes affiliated with Otomycosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Otomycosis

Search GEO for disease gene expression data for Otomycosis.

Pathways for genes affiliated with Otomycosis

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Sources:
51PathCards, 61Thomson Reuters, 39NCBI BioSystems Database, 56Reactome, 54QIAGEN, 31KEGG, 13EMD Millipore
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Pathways related to Otomycosis according to GeneCards/GeneDecks:

(show top 50)    (show all 102)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
IFN-gamma pathway39
8.5CALM1, CALM3, CALM2
28.5CALM1, CALM3, CALM2
38.5CALM1, CALM3, CALM2
4
Show member pathways
8.5CALM1, CALM3, CALM2
5
Show member pathways
8.5CALM1, CALM3, CALM2
68.5CALM1, CALM3, CALM2
78.5CALM1, CALM3, CALM2
8
Show member pathways
8.5CALM1, CALM3, CALM2
98.5CALM1, CALM3, CALM2
108.5CALM1, CALM3, CALM2
11
Show member pathways
8.5CALM1, CALM3, CALM2
12
Show member pathways
p38 MAPK signaling pathway39
8.5CALM1, CALM3, CALM2
138.5CALM1, CALM3, CALM2
14
Show member pathways
Development Ligand independent activation of ESR1 and ESR261
8.5CALM1, CALM3, CALM2
158.5CALM2, CALM1, CALM3
16
Show member pathways
malate-aspartate shuttle39
glycogen biosynthesis II (from UDP-D-Glucose)39
8.5CALM2, CALM3, CALM1
17
Show member pathways
Development Activation of ERK by Alpha 1 adrenergic receptors61
8.5CALM1, CALM2, CALM3
18
Show member pathways
8.5CALM2, CALM3, CALM1
19
Show member pathways
8.5CALM2, CALM3, CALM1
20
Show member pathways
8.5CALM3, CALM2, CALM1
21
Show member pathways
Immune response MIF in innate immunity response61
8.5CALM2, CALM3, CALM1
22
Show member pathways
Signal transduction cAMP signaling61
8.5CALM3, CALM2, CALM1
23
Show member pathways
Development Role of HDAC and calcium calmodulin dependent kinase CaMK in control of skeletal myogenesis61
8.5CALM2, CALM1, CALM3
24
Show member pathways
8.5CALM1, CALM2, CALM3
25
Show member pathways
8.5CALM1, CALM2, CALM3
26
Show member pathways
8.5CALM2, CALM1, CALM3
27
Show member pathways
8.5CALM2, CALM1, CALM3
28
Show member pathways
VEGFR1 specific signals39
8.5CALM2, CALM3, CALM1
29
Show member pathways
IL2 signaling events mediated by STAT539
8.5CALM1, CALM2, CALM3
30
Show member pathways
Ras signaling in the CD4+ TCR pathway39
8.5CALM1, CALM2, CALM3
318.5CALM2, CALM3, CALM1
328.5CALM1, CALM2, CALM3
338.5CALM2, CALM3, CALM1
348.5CALM2, CALM3, CALM1
358.5CALM2, CALM3, CALM1
368.5CALM2, CALM1, CALM3
37
Show member pathways
8.5CALM3, CALM2, CALM1
388.5CALM3, CALM2, CALM1
39
Show member pathways
8.5CALM1, CALM2, CALM3
40
Show member pathways
EPO Receptor Signaling39
EPO signaling pathway39
8.5CALM2, CALM1, CALM3
41
Show member pathways
Calcium signaling in the CD4+ TCR pathway39
8.5CALM3, CALM2, CALM1
428.5CALM3, CALM2, CALM1
438.5CALM3, CALM1, CALM2
44
Show member pathways
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis39
inositol pyrophosphates biosynthesis39
D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis39
8.5CALM3, CALM1, CALM2
45
Show member pathways
8.5CALM3, CALM1, CALM2
468.5CALM3, CALM1, CALM2
478.5CALM3, CALM1, CALM2
48
Show member pathways
8.5CALM3, CALM1, CALM2
498.5CALM3, CALM1, CALM2
50
Show member pathways
D-myo-inositol-5-phosphate metabolism39
superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism39
D-myo-inositol (1,4,5)-trisphosphate degradation39
superpathway of inositol phosphate compounds39
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)39
D-myo-inositol (1,4,5)-trisphosphate biosynthesis39
myo-inositol biosynthesis39
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)39
D-myo-inositol (1,3,4)-trisphosphate biosynthesis39
8.5CALM3, CALM1, CALM2

Compounds for genes affiliated with Otomycosis

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GO Terms for genes affiliated with Otomycosis

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Products for genes affiliated with Otomycosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Otomycosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet