MCID: OTM001
MIFTS: 22

Otomycosis malady

Ear diseases category
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Summaries for Otomycosis

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Disease Ontology:8 A otitis externa which is a disease of the ear produced by the growth of fungi in the external auditory canal. it is characterized by inflammation, pruritus, scaling and severe discomfort. the most common fungi are aspergillus niger and candida albicans.

MalaCards based summary: Otomycosis, also known as singapore ear, is related to coccidioidomycosis and chronic fungal otitis externa. An important gene associated with Otomycosis is CALM3 (calmodulin 3 (phosphorylase kinase, delta)), and among its related pathways are Translation Translation regulation by Alpha 1 adrenergic receptors and Pertussis.

Wikipedia:65 Otomycosis (also known as Singapore Ear) is a fungal ear infection, a superficial mycotic infection of... more...

Aliases & Classifications for Otomycosis

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Otomycosis, Aliases & Descriptions:

Name: Otomycosis 8 10 62
 
Singapore Ear 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


External Ids:

Disease Ontology8 DOID:0050147

Related Diseases for Otomycosis

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Diseases related to Otomycosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1coccidioidomycosis10.1
2chronic fungal otitis externa10.1
3middle ear disease10.1
4otitis externa10.1
5pseudoachondroplasia9.7CALM2, CALM3, CALM1
6malignant hyperthermia9.6CALM1, CALM3, CALM2
7pertussis9.6CALM2, CALM3, CALM1
8vascular disease9.6CALM1, CALM3, CALM2
9toxic encephalopathy9.6CALM1, CALM3, CALM2
10cholera9.5CALM2, CALM3, CALM1

Graphical network of diseases related to Otomycosis:



Diseases related to otomycosis

Symptoms for Otomycosis

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Drugs & Therapeutics for Otomycosis

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Drug clinical trials:

Search ClinicalTrials for Otomycosis

Search NIH Clinical Center for Otomycosis

Genetic Tests for Otomycosis

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Anatomical Context for Otomycosis

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Animal Models for Otomycosis or affiliated genes

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Publications for Otomycosis

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Articles related to Otomycosis:

(show top 50)    (show all 117)
idTitleAuthorsYear
1
Primary otomycosis in the Indian subcontinent: predisposing factors, microbiology, and classification. (24949016)
2014
2
Otomycosis; clinical features, predisposing factors and treatment implications. (24948980)
2014
3
Treatment of refractory Aspergillus otomycosis with voriconazole: case series and review. (24909800)
2014
4
Efficacy of topical clotrimazole in treatment of otomycosis. (25098061)
2013
5
Otomycosis in Shanghai: aetiology, clinical features and therapy. (21999222)
2012
6
Species assignment and antifungal susceptibilities of black aspergilli recovered from otomycosis cases in Iran. (21895787)
2012
7
Otomycosis due to filamentous fungi. (21499908)
2011
8
Antibiotic resistance and otomycosis in the draining ear: culture results by diagnosis. (21041003)
2011
9
Chronic monolateral otomycosis in a dog caused by Aspergillus ochraceus. (20409075)
2010
10
Otomycosis due to Aspergillus spp. in a dog: case report and literature review. (20492628)
2010
11
Chronic otomycosis due to malassezia spp. (20606976)
2010
12
Otomycosis: a retrospective study. (19649486)
2009
13
Aspergillus otomycosis in an immunocompromised patient. (19006061)
2008
14
Ototopical antifungals and otomycosis: a review. (18279975)
2008
15
Scedosporium apiospermum otomycosis. (17606042)
2007
16
Suction clearance and 2% topical miconazole versus the same combination with acidic drops in the treatment of otomycosis. (17883017)
2007
17
Chronic bilateral otomycosis caused by Aspergillus niger. (14998406)
2004
18
In vitro activity of terbinafine and itraconazole against Aspergillus species isolated from otomycosis. (15310330)
2004
19
Concomitant otomycosis and dermatomycoses: a clinical and microbiological study. (12520352)
2003
20
Otomycosis. (12092275)
2002
21
Treatment outcome of otomycosis in Ilorin, Nigeria. (12081339)
2002
22
Otomycosis with pus. (12149832)
2002
23
Randomized prospective comparative study: short-term treatment with ciclopiroxolamine (cream and solution) versus boric acid in the treatment of otomycosis. (12572722)
2002
24
In vitro evaluation of sulfadrugs against fungi causing otomycosis. (15061593)
2002
25
The fungal profile of otomycosis patients in Ilorin, Nigeria. (11806011)
2001
26
Otomycosis: the detection of fungi in ears by immunofluorescence microscopy. (9222637)
1997
27
Otomycosis--a clinico-mycological study and efficacy of mercurochrome in its treatment. (9008878)
1996
28
Calcium oxalate crystal deposition in necrotizing otomycosis caused by Aspergillus niger. (8415598)
1993
29
Antimycotic effect of fixed oils treated with herbal seeds on the growth of fungi causing otomycosis. (22556643)
1993
30
A microbiological study of otomycosis in Visakhapatnam. (3429879)
1987
31
Broad spectrum antifungal agents in otomycosis. (3746101)
1986
32
Otomycosis: an experimental evaluation of six antimycotic agents. (6461705)
1982
33
"How I do it"--otology and neurotology. A specific issue and its solution. Merthiolate in treatment of otomycosis. (7242211)
1981
34
Topical 5-fluorocytosine therapy in otomycosis. (4595093)
1974
35
Studies on experimental otomycosis in dogs. (4783390)
1973
36
Otomycosis due to Aspergillus niger. (5473595)
1970
37
Otomycosis: an entity. (4224861)
1967
38
Otomycosis: a clinical entity--clinical and experimental study. (6050987)
1967
39
Tropical otomycosis. (6050986)
1967
40
Otomycosis: an entity, not a myth. (6071123)
1967
41
THE MYTH OF OTOMYCOSIS. (14233233)
1965
42
Otomycosis. (13241530)
1955
43
Etiology of otomycosis; bacterial flora of the ear. (15433689)
1950
44
Relation of various fungi to otomycosis. (20265711)
1947
45
Otomycosis; some remarks concerning its diagnosis and treatment. (20996337)
1946
46
Pathogenicity of the aspergilli of otomycosis. (20999058)
1946
47
Etiology of otomycosis. (20999806)
1946
48
Otomycosis. (21025558)
1946
49
Management of otomycosis. (21004521)
1945
50
Case of Otomycosis. (19985146)
1926

Variations for Otomycosis

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Expression for genes affiliated with Otomycosis

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Expression patterns in normal tissues for genes affiliated with Otomycosis

Search GEO for disease gene expression data for Otomycosis.

Pathways for genes affiliated with Otomycosis

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Pathways related to Otomycosis according to GeneCards/GeneDecks:

(show top 50)    (show all 102)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Development Activation of ERK by Alpha 1 adrenergic receptors60
8.5CALM1, CALM3, CALM2
28.5CALM1, CALM3, CALM2
3
Show member pathways
malate-aspartate shuttle37
glycogen biosynthesis II (from UDP-D-Glucose)37
8.5CALM1, CALM3, CALM2
4
Show member pathways
8.5CALM1, CALM3, CALM2
58.5CALM1, CALM3, CALM2
6
Show member pathways
8.5CALM1, CALM3, CALM2
7
Show member pathways
EPO Receptor Signaling37
EPO signaling pathway37
8.5CALM1, CALM3, CALM2
8
Show member pathways
8.5CALM1, CALM3, CALM2
98.5CALM1, CALM3, CALM2
10
Show member pathways
8.5CALM1, CALM3, CALM2
11
Show member pathways
8.5CALM1, CALM3, CALM2
12
Show member pathways
Development Ligand independent activation of ESR1 and ESR260
8.5CALM1, CALM3, CALM2
13
Show member pathways
D-myo-inositol-5-phosphate metabolism37
superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism37
D-myo-inositol (1,4,5)-trisphosphate degradation37
superpathway of inositol phosphate compounds37
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)37
D-myo-inositol (1,4,5)-trisphosphate biosynthesis37
myo-inositol biosynthesis37
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)37
D-myo-inositol (1,3,4)-trisphosphate biosynthesis37
8.5CALM1, CALM3, CALM2
14
Show member pathways
8.5CALM1, CALM3, CALM2
15
Show member pathways
Development Role of HDAC and calcium calmodulin dependent kinase CaMK in control of skeletal myogenesis60
8.5CALM1, CALM3, CALM2
16
Show member pathways
IL2 signaling events mediated by STAT537
8.5CALM1, CALM3, CALM2
17
Show member pathways
VEGFR1 specific signals37
8.5CALM1, CALM3, CALM2
18
Show member pathways
p38 MAPK signaling pathway37
8.5CALM1, CALM3, CALM2
198.5CALM1, CALM3, CALM2
208.5CALM1, CALM3, CALM2
218.5CALM1, CALM3, CALM2
228.5CALM1, CALM3, CALM2
238.5CALM1, CALM3, CALM2
24
Show member pathways
8.5CALM1, CALM3, CALM2
258.5CALM1, CALM3, CALM2
268.5CALM1, CALM3, CALM2
278.5CALM1, CALM3, CALM2
28
Show member pathways
8.5CALM2, CALM3, CALM1
298.5CALM2, CALM3, CALM1
308.5CALM2, CALM3, CALM1
31
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
8.5CALM2, CALM3, CALM1
328.5CALM2, CALM3, CALM1
33
Show member pathways
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis37
inositol pyrophosphates biosynthesis37
D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis37
8.5CALM2, CALM3, CALM1
34
Show member pathways
8.5CALM2, CALM3, CALM1
35
Show member pathways
8.5CALM2, CALM3, CALM1
36
Show member pathways
Ras signaling in the CD4+ TCR pathway37
8.5CALM2, CALM3, CALM1
37
Show member pathways
Immune response MIF in innate immunity response60
8.5CALM2, CALM3, CALM1
38
Show member pathways
Signal transduction cAMP signaling60
8.5CALM2, CALM3, CALM1
39
Show member pathways
8.5CALM2, CALM3, CALM1
40
Show member pathways
8.5CALM2, CALM3, CALM1
418.5CALM2, CALM3, CALM1
428.5CALM2, CALM3, CALM1
43
Show member pathways
IFN-gamma pathway37
8.5CALM2, CALM3, CALM1
448.5CALM2, CALM3, CALM1
458.5CALM2, CALM3, CALM1
468.5CALM2, CALM3, CALM1
47
Show member pathways
8.5CALM2, CALM3, CALM1
488.5CALM2, CALM3, CALM1
49
Show member pathways
8.5CALM2, CALM3, CALM1
50
Show member pathways
8.5CALM2, CALM3, CALM1

Compounds for genes affiliated with Otomycosis

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GO Terms for genes affiliated with Otomycosis

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Products for genes affiliated with Otomycosis

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Sources for Otomycosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet