MCID: OTM001
MIFTS: 22

Otomycosis malady

Ear diseases category

Summaries for Otomycosis

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A otitis externa which is a disease of the ear produced by the growth of fungi in the external auditory canal. it is characterized by inflammation, pruritus, scaling and severe discomfort. the most common fungi are aspergillus niger and candida albicans.

MalaCards: Otomycosis, also known as singapore ear, is related to coccidioidomycosis and chronic fungal otitis externa. An important gene associated with Otomycosis is CALM3 (calmodulin 3 (phosphorylase kinase, delta)), and among its related pathways are Development EPO-induced Jak-STAT pathway and Thromboxane signalling through TP receptor.

Wikipedia:63 Otomycosis (also known as Singapore Ear) is a fungal ear infection, a superficial mycotic infection of... more...

Aliases & Classifications for Otomycosis

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

otomycosis 8 10 60
singapore ear 8


External Ids:

Disease Ontology8 DOID:0050147

Related Diseases for Otomycosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Otomycosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1coccidioidomycosis10.0
2chronic fungal otitis externa10.0
3middle ear disease10.0
4otitis externa10.0
5pseudoachondroplasia10.0CALM1, CALM2, CALM3
6toxic encephalopathy10.0CALM3, CALM2, CALM1
7malignant hyperthermia10.0CALM1, CALM2, CALM3
8vascular disease10.0CALM3, CALM2, CALM1
9cholera10.0CALM3, CALM2, CALM1
10pertussis10.0CALM1, CALM2, CALM3

Graphical network of diseases related to Otomycosis:



Diseases related to otomycosis

Clinical Features for Otomycosis

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Drugs & Therapeutics for Otomycosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Otomycosis

Drug clinical trials:

Search ClinicalTrials for Otomycosis

Search NIH Clinical Center for Otomycosis

Search CenterWatch for Otomycosis

Genetic Tests for Otomycosis

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Anatomical Context for Otomycosis

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Animal Models for Otomycosis or affiliated genes

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Publications for Otomycosis

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Sources:
50PubMed
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Articles related to Otomycosis:

(show top 50)    (show all 117)
idTitleAuthorsYear
1
Prevalence of otomycosis in Khouzestan Province, south-west Iran. (23164073)
2013
2
Effectiveness of 7.5 percent povidone iodine in comparison to 1 percent clotrimazole with lignocaine in the treatment of otomycosis. (23984100)
2013
3
Otomycosis in Shanghai: aetiology, clinical features and therapy. (21999222)
2012
4
Species assignment and antifungal susceptibilities of black aspergilli recovered from otomycosis cases in Iran. (21895787)
2012
5
Otomycosis in immunocompetent and immunocompromised patients: comparative study and literature review. (22430336)
2012
6
Molecular identification and antifungal susceptibilities of black Aspergillus isolates from otomycosis cases in Hungary. (22359155)
2012
7
Antibiotic resistance and otomycosis in the draining ear: culture results by diagnosis. (21041003)
2011
8
A clinical study on the effect of Arka Taila in the management of Karnasrava (Otomycosis). (22529649)
2011
9
Otomycosis in central iran: a clinical and mycological study. (22737432)
2011
10
Otomycosis due to Aspergillus spp. in a dog: case report and literature review. (20492628)
2010
11
Chronic otomycosis due to malassezia spp. (20606976)
2010
12
Aspergillus otomycosis in an immunocompromised patient. (19006061)
2008
13
Ototopical antifungals and otomycosis: a review. (18279975)
2008
14
Scedosporium apiospermum otomycosis. (17606042)
2007
15
In vitro susceptibilities of Aspergillus spp. causing otomycosis to amphotericin B, voriconazole and itraconazole. (17944704)
2007
16
Otomycosis: subdermal growth in calcified mass. (16799802)
2006
17
Otomycosis: clinical and mycological study of 97 cases. (17315791)
2006
18
A case of otomycosis caused by Aspergillus sclerotiorum. (15729874)
2004
19
Treatment outcome of otomycosis in Ilorin, Nigeria. (12081339)
2002
20
The fungal profile of otomycosis patients in Ilorin, Nigeria. (11806011)
2001
21
Otomycosis in Nigeria: treatment with mercurochrome. (11766105)
2001
22
Prevalence of otomycosis in malnourished children in Edo State, Nigeria. (9646512)
1997-1998
23
Otomycosis--a clinico-mycological study and efficacy of mercurochrome in its treatment. (9008878)
1996
24
Fungitoxic effect of some organic volatile substances against fungi causing otomycosis. (7739663)
1994
25
Otomycosis in SALo Paulo. (1844531)
1991
26
Etiological agents of otomycosis in Nigeria. (2503721)
1989
27
In vitro effectiveness of 13 agents in otomycosis and review of the literature. (3054372)
1988
28
A microbiological study of otomycosis in Visakhapatnam. (3429879)
1987
29
Clotrimazole powder in the treatment of otomycosis. (3694750)
1987
30
Fungal isolates in otomycosis. (6892339)
1982
31
Otomycosis in Burma, and its treatment. (6447461)
1980
32
Otitis externa--4: Otomycosis. (1048789)
1976
33
Studies on experimental otomycosis in dogs. (4783390)
1973
34
Polypaecilum insolitum (=Scopulariopsis divaricata) isolated from cases of otomycosis. (5065134)
1972
35
Root-like hyphal structures in aspergillar otomycosis. (4681322)
1972
36
Otomycosis due to Aspergillus niger. (5473595)
1970
37
Otomycosis: a clinical entity--clinical and experimental study. (6050987)
1967
38
Otomycosis: an entity, not a myth. (6071123)
1967
39
Otomycosis. (13956921)
1962
40
Otomycosis: a neglected disease. (13708423)
1961
41
Otomycosis. (13241530)
1955
42
Trichosporon cutaneum isolated from a case of otomycosis. (13301724)
1955
43
The action of trichomycin upon middle ear disease due to yeast and otomycosis. (13211483)
1954
44
Etiology of otomycosis; clinical observations. (15433692)
1950
45
Etiology of otomycosis; mycologic flora of the ear. (15433688)
1950
46
Otomycosis. (18905159)
1948
47
Otomycosis; some remarks concerning its diagnosis and treatment. (20996337)
1946
48
Pathogenicity of the aspergilli of otomycosis. (20999058)
1946
49
Management of otomycosis. (21004521)
1945
50
Otomycosis in the Tropics. (20759337)
1900

Genetic Variations for Otomycosis

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Expression for genes affiliated with Otomycosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Otomycosis

Search GEO for disease gene expression data for Otomycosis.

Pathways for genes affiliated with Otomycosis

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Sources:
12EMD Millipore, 53Reactome, 37NCBI BioSystems Database, 29KEGG, 51QIAGEN
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Pathways related to Otomycosis according to GeneCards/GeneDecks:

(show top 50)    (show all 83)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Development EPO-induced Jak-STAT pathway
Hide members
8.9CALM3, CALM1, CALM2
2
Hide members
8.9CALM1, CALM3, CALM2
38.9CALM1, CALM3, CALM2
4
Hide members
8.9CALM3, CALM1, CALM2
58.9CALM1, CALM3, CALM2
6
Hide members
8.9CALM3, CALM1, CALM2
78.9CALM1, CALM3, CALM2
88.9CALM1, CALM3, CALM2
98.9CALM3, CALM1, CALM2
10
Hide members
8.9CALM3, CALM1, CALM2
118.9CALM3, CALM1, CALM2
128.9CALM2, CALM3, CALM1
13
Hide members
8.9CALM2, CALM3, CALM1
14
Immune response ICOS pathway in T-helper cell
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8.9CALM2, CALM3, CALM1
15
Hide members
8.9CALM3, CALM2, CALM1
16
Immune response NFAT in immune response
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8.9CALM3, CALM2, CALM1
17
Hide members
8.9CALM3, CALM2, CALM1
18
Signal transduction IP3 signaling
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8.9CALM3, CALM2, CALM1
19
Signal transduction cAMP signaling
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8.9CALM2, CALM1, CALM3
20
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8.9CALM2, CALM3, CALM1
21
Development Ligand-independent activation of ESR1 and ESR2
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8.9CALM1, CALM2, CALM3
228.9CALM1, CALM2, CALM3
238.9CALM3, CALM2, CALM1
24
Hide members
8.9CALM3, CALM2, CALM1
258.9CALM3, CALM2, CALM1
268.9CALM3, CALM2, CALM1
27
Hide members
8.9CALM2, CALM3, CALM1
28
Hide members
8.9CALM3, CALM2, CALM1
29
Hide members
8.9CALM2, CALM3, CALM1
30
Immune response IFN gamma signaling pathway
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8.9CALM1, CALM2, CALM3
318.9CALM1, CALM2, CALM3
328.9CALM3, CALM2, CALM1
338.9CALM2, CALM1, CALM3
348.9CALM2, CALM3, CALM1
358.9CALM3, CALM2, CALM1
368.9CALM3, CALM2, CALM1
378.9CALM3, CALM2, CALM1
388.9CALM3, CALM2, CALM1
398.9CALM3, CALM2, CALM1
408.9CALM1, CALM2, CALM3
418.9CALM1, CALM2, CALM3
428.9CALM2, CALM1, CALM3
43
Translation Translation regulation by Alpha-1 adrenergic receptors
Hide members
8.9CALM1, CALM2, CALM3
448.9CALM3, CALM2, CALM1
458.9CALM2, CALM1, CALM3
46
Hide members
8.9CALM3, CALM2, CALM1
478.9CALM1, CALM2, CALM3
48
Hide members
8.9CALM2, CALM1, CALM3
498.9CALM1, CALM2, CALM3
508.1CALM2, OR4F29, CALM3, CALM1

Compounds for genes affiliated with Otomycosis

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GO Terms for genes affiliated with Otomycosis

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Products for genes affiliated with Otomycosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Otomycosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet