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MCID: OVR042

Ovarian Cancer malady
41 drugs, 1659 genes, 25 tissues, 1523 related diseases, 29 phenotypes, 3611 articles, clinical trials.

Summaries for Ovarian Cancer

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23MedlinePlus, 2CDC, 44Wikipedia, 22MalaCards
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MedlinePlus: Ovarian cancer usually happens in women over age 50, but it can also affect younger women. its cause is unknown. ovarian cancer is hard to detect early. the sooner ovarian cancer is found and treated, the better your chance for recovery. but ovarian cancer is hard to detect early. many times, women with ovarian cancer have no symptoms or just mild symptoms until the disease is in an advanced stage and hard to treat. symptoms may include: heavy feeling in pelvis pain in lower abdomen bleeding from the vagina weight gain or loss abnormal periods unexplained back pain that gets worse gas, nausea, vomiting, or loss of appetite treatment is usually surgery followed by treatment with medicines called chemotherapy.23

MalaCards: Ovarian Cancer, also known as ovarian neoplasm, is related to carcinoma and prostatitis. An important gene associated with Ovarian Cancer is BRCA1 (breast cancer 1, early onset), and among its related pathways are Tec Kinases Signaling and Cell Cycle / Checkpoint Control. The drugs chlorambucil and prednisone and the compounds atp and paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and lymph node, and related mouse phenotypes are homeostasis/metabolism and mortality/aging.

CDC: Cancer is a disease in which cells in the body grow out of control. Cancer is always named for the part of the body where it starts, even if it spreads to other body parts later. When cancer starts in the ovaries, it is called ovarian cancer. Women have two ovaries that are located in the pelvis, one on each side of the uterus. The ovaries make female hormones and produce eggs.2

Wikipedia: Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early...44 more...

Aliases & Descriptions for Ovarian Cancer

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6Disease Ontology, 7diseasecard, 30NIH Rare Diseases, 8DISEASES, 33OMIM, 32Novoseek , 23MedlinePlus, 2CDC, 43UMLS, 24MeSH, 40SNOMED-CT, 27NCIt
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Aliases & Descriptions:

ovarian cancer 6 7 30 8 33 32 23
ovarian neoplasm 6 43
primary malignant neoplasm of ovary and other uterine adnexa (disorder) 6
malignant tumor of ovary (disorder) 6
neoplasm of ovary (disorder) 6
malignant neoplasm of ovary 43
primary malignant neoplasm 43
malignant tumour of ovary 6
malignant ovarian tumor 6
primary ovarian cancer 6
malignant neoplasms 43
tumor of the ovary 6
ovarian carcinoma 30
ovarian neoplasms 32
ovary neoplasm 6
ovary cancer 6
neoplasms 43

Related Diseases for Ovarian Cancer

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13GeneCards, 14GeneDecks
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Diseases related to ovarian cancer by text searches and GeneDecks gene sharing:

(show top 50)    (show all 1520)
idRelated DiseaseScoreTop Affiliating Genes
1carcinoma315.5ZNF673, ZNF217, ZNF354A, ZNF23, PIK3CB, PIK3CA
2prostatitis270.8ZNF673, PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG
3adenocarcinoma238.5ZNF217, PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1
4leukemia237.8ZNF673, PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG
5pancreatitis226.6PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, LRP1
6neuronitis210.4PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, LRP1
7hepatocellular carcinoma201.7PIK3CB, PIK3CA, PIK3R1, PIK3CG, KLF6, NCAM1
8melanoma198.7PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, LRP1
9thyroiditis196.6PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLF10
10gastric cancer196.3PIK3CB, PIK3CA, PIK3R1, PIK3CG, KLF6, NCOA3
11epithelial ovarian cancer192.7PIK3CB, PIK3CA, PIK3R3, PIK3CG, KLB, RGCC
12cervicitis188.4ZNF350, ZNF217, PIK3CA, PIK3CG, PDCD1, PDCD4
13colon cancer183.9PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, KLF6
14esophagitis180.4ZNF673, PIK3CB, PIK3CA, PIK3CG, KLF6, NCAM1
15breast carcinoma177.9ZNF217, PIK3CA, PIK3R1, PIK3CG, LRP1, NCOA3
16ovarian carcinoma168.6PIK3CA, PIK3CG, NCOA3, PDCD4, RECK, RELA
17hypoxia158.8ZNF217, ZNF354A, PIK3CB, PIK3CA, PIK3R1, PIK3CG
18adenoma151.1PIK3CA, NCAM1, NCOA1, NCOA3, NCOR1, NCOR2
19sarcoma150.4PIK3CB, PIK3CA, PIK3R1, PIK3CG, NCAM1, NCOA1
20neuroblastoma147.9PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLF6
21myeloid leukemia143.9ZNF673, PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG
22cervical cancer141.1ZNF350, ZNF217, PIK3CA, PIK3CG, PDCD1, RELA
23lung carcinoma134.0PIK3CA, PIK3R1, PIK3CG, KLF6, NCAM1, RECK
24cholesterol128.4PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLB
25endometrial cancer127.8PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, NCOA1
26fibrosis127.3PIK3CA, PIK3CG, LRP1, KLF6, NCF1, NCOA3
27colon carcinoma127.1PIK3CB, PIK3CA, PIK3R1, PIK3CG, NCAM1, PDCD4
28osteosarcoma122.2PIK3CB, PIK3CA, PIK3CG, KLF10, NCOA1, RECK
29cerebritis118.0PIK3R1, PIK3CG, LRP1, KLF6, NCAM1, NCF1
30atherosclerosis114.4ZNF673, PIK3CG, LRP1, KLF10, NCF1, PDCD1
31lymphocytic leukemia112.3PIK3CA, PIK3CG, NCAM1, RECK, RELA, RELB
32acute myeloid leukemia111.1ZNF673, PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG
33peritonitis110.1LRP1, RELA, RELB, SGK1, KIT, KITLG
34endometrial carcinoma109.9PIK3CB, PIK3CA, PIK3CG, LRP1, NCOA1, NCOA3
35astrocytoma109.7PIK3CA, PIK3R1, PIK3CG, LRP1, KLF6, NCAM1
36lymphoblastic leukemia106.8PIK3CA, PIK3CG, KLF10, NCAM1, NCOA3, RECK
37retinoblastoma106.3PIK3CB, PIK3CA, PIK3R1, PIK3CG, KLF6, NCAM1
38endometriosis105.1PIK3CA, NCOA1, NCOR1, NCOR2, RELA, KITLG
39tuberculosis104.1PIK3CG, NCF1, PDCD1, RELA, RELB, CNTN6
40obesity103.7ZNF318, PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1
41esophageal cancer100.9PIK3CB, PIK3CA, PIK3CG, PDCD4, KITLG, PCNA
42diabetes mellitus100.9ZNF673, PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG
43cervical carcinoma100.5PIK3CA, PIK3CG, PDCD1, RECK, RELA, KIT
44thyroid cancer99.7PIK3CA, PIK3R1, PIK3CG, NCOA3, NCOA4, KIT
45thyroid carcinoma98.1PIK3CA, PIK3CG, KITLG, SFN, PCNA, RB1
46laryngitis97.8PIK3CA, PDCD4, RELA, SFN, PCNA, RB1
47anemia94.8NCAM1, NCOR1, PDCD1, RELA, SGCB, SGK1
48meningioma94.7PIK3CG, NCAM1, NCOA3, PCNA, RB1, NBN
49arthritis92.2PIK3CG, LRP1, NCF1, PDCD1, RECK, RELA
50cholangiocarcinoma91.6PIK3CA, PIK3CG, NCAM1, PDCD4, RECK, KIT

Graphical network of the top 20 diseases related to ovarian cancer:



Graphical network of diseases related to ovarian cancer

Clinical Features for Ovarian Cancer

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Drugs & Therapeutics for Ovarian Cancer

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

Search CenterWatch for ovarian cancer

Drug clinical trials:

Search ClinicalTrials for ovarian cancer

Search NIH Clinical Center for ovarian cancer

Search CenterWatch for ovarian cancer

Inferred drug relations via UMLS/NDF-RT:

43 28 altretamine, carboplatin, chlorambucil, chromic phosphate,p-32, cisplatin, cisplatin pwdr [va product], cyclophosphamide, dexamethasone, dexamethasone acetate, dexamethasone acetate pwdr [va product], dexamethasone phosphate, dexamethasone sodium phosphate, dexamethasone sodium phosphate pwdr [va product], docetaxel, doxorubicin, doxorubicin hydrochloride, doxorubicin hydrochloride liposome, hydroxyurea, ifosfamide, leuprolide, leuprolide acetate, linolenic acid, melphalan, melphalan hydrochloride, methylprednisolone, methylprednisolone acetate, methylprednisolone sodium succinate, paclitaxel, prednisolone, prednisolone acetate, prednisolone acetate pwdr [va product], prednisolone pwdr [va product], prednisolone sodium phosphate, prednisolone tebutate, prednisone, prednisone pwdr [va product], topotecan, topotecan hydrochloride, uracil mustard, vinorelbine, vinorelbine tartrate

Genetic Tests for Ovarian Cancer

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Anatomical Context for Ovarian Cancer

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22MalaCards
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MalaCards organs/tissues related to ovarian cancer:

22
Bone marrow, Whole blood, Lymph node, Spleen, Smooth muscle, Small intestine, Colon, Liver, Lung, Thyroid, Breast, Ovary, Uterus, Placenta, Prostate, Testis, Myeloid, Monocytes, Nk cells, T cells, B cells, Endothelial, Pons, Pituitary, Testis germ

Phenotypes for genes affiliated with Ovarian Cancer

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25MGI
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MGI Mouse Phenotypes related to ovarian cancer:

25 (show all 29)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1homeostasis/metabolism phenotypeMP:0005376111.9PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLB
2mortality/agingMP:001076899.9PIK3CB, PIK3CA, LRP1, KLF6, NCAM1, NCOR1
3nervous system phenotypeMP:000363171.6LRP1, NCOA1, NCOR1, PDCD1, RECK, RELA
4behavior/neurological phenotypeMP:000538664.6PIK3CA, LRP1, NCAM1, NCOA1, NCOA3, NCOR1
5reproductive system phenotypeMP:000538960.4PIK3CA, KLF6, NCOA1, NCOA3, PDCD4, KISS1
6normal phenotypeMP:000287357.3PIK3R1, LRP1, RELA, KISS1R, VTCN1, VTN
7embryogenesis phenotypeMP:000538056.0PIK3CB, PIK3CA, KLF6, NCOA1, NCOA3, NCOR1
8skeleton phenotypeMP:000539055.6PIK3CG, LRP1, KLF10, NCOA1, RECK, RELA
9integument phenotypeMP:001077155.4PIK3CG, KLF10, KLF6, NCOA1, NCOA3, NCOR1
10muscle phenotypeMP:000536954.7PIK3CA, PIK3R1, PIK3CG, LRP1, NCOA3, NCOR1
11digestive/alimentary phenotypeMP:000538153.3NCOA3, NCOR2, RELB, KIT, KISS1, KITLG
12renal/urinary system phenotypeMP:000536739.8NCOA1, NCOA3, PDCD1, PDCD4, SGK1, KIT
13limbs/digits/tail phenotypeMP:000537136.3KLF10, RECK, RELA, RELB, KIT, KITLG
14endocrine/exocrine gland phenotypeMP:000537936.0KLB, NCOA1, PDCD4, RELB, KISS1, KISS1R
15liver/biliary system phenotypeMP:000537032.4KLB, KLF6, NCOA3, NCOR1, NCOR2, RECK
16craniofacial phenotypeMP:000538231.4NCOA3, NCOR2, KIT, KITLG, PCSK6, RBL1
17no phenotypic analysisMP:000301230.1PIK3R1, REST, SGK1, PCNA, BUB1, RB1
18hearing/vestibular/ear phenotypeMP:000537727.8NCOA3, KIT, KITLG, SFN, RB1, RBP1
19pigmentation phenotypeMP:000118622.6KIT, KITLG, RB1, RBP1, SERPINC1, SERPINF1
20respiratory system phenotypeMP:000538822.3RELB, PCSK6, BRCA1, LPAR2, BOC, MYCN
21vision/eye phenotypeMP:0005391INFPIK3CA, NCAM1, PDCD1, RELA, REST, KIT
22tumorigenesisMP:0002006INFPIK3CB, PIK3CA, PIK3R1, KLF10, NCOA3, PDCD4
23adipose tissue phenotypeMP:0005375INFPIK3CA, PIK3R1, LRP1, NCOA3, NCOR1, NCOR2
24cardiovascular system phenotypeMP:0005385INFPIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLF6
25hematopoietic system phenotypeMP:0005397INFKLF6, PDCD1, KIT, KISS1R, VTCN1, SFN
26growth/size phenotypeMP:0005378INFPIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLB
27cellular phenotypeMP:0005384INFPIK3CB, PIK3CA, PIK3R1, PIK3CG, KLF10, KLF6
28immune system phenotypeMP:0005387INFLRP1, NCOA1, NCOA3, NCOR1, PDCD4, RELB
29other phenotypeMP:0005395INFRECK, RELB, BUB1, RARA, RARB, CLU

Publications for genes affiliated with Ovarian Cancer

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35PubMed
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Articles related to ovarian cancer:

(show top 50)    (show all 3611)
idTitleAuthorsYearAffiliating Genes
1Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. (21990120)Thompson E.R.... Campbell I.G.2012RAD51C
2Knockdown of splicing factor SRp20 causes apoptosis i n ovarian cancer cells and its expression is associated with malignancy of epit helial ovarian cancer. (20856201)He X.... Beck W.T.2011SRSF3
3Endometrioid ovarian cancer and endometriotic cells e xhibit the same alteration in the expression of interleukin-1 receptor II: to a link between endometriosis and endometrioid ovarian cancer. (21083841)Keita M.... Aris A.2011IL1R1, IL1R2
4Effects of ovarian cancer G protein coupled receptor 1 on the proliferation, migration, and adhesion of human ovarian cancer cells. (21740742)Ren J.... Zhang L.2011GPR68
5Lost expression of DCC gene in ovarian cancer and its inhibition in ovarian cancer cells. (20054719)Meimei L.... Chunjie H.2011DCC
6Aberrant methylation of breast and ovarian cancer sus ceptibility gene 1 in chemosensitive human ovarian cancer cells does not involv e the phosphatidylinositol 3'-kinase-Akt pathway. (20487263)Wang Y.Q.... Wan X.P.2010BRCA1
7Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth. (20429876)Yallapu M.M.... Chauhan S.C.2010CTNNB1, PARP1, BCL2L1
8Role of the 18:1 lysophosphatidic acid-ovarian cancer immunoreactive antigen domain containing 1 (OCIAD1)-integrin axis in generatin g late-stage ovarian cancer. (20515946)Wang C.... Sengupta S.2010OCIAD1
9Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. (19127255)Pearce C.L.... .2009COMT, CYP1A1, CYP1B1
10E-cadherin expression in ovarian cancer in the laying hen, Gallus domesticus, compared to human ovarian cancer. (19321195)Ansenberger K.... Hales D.B.2009CDH1
11Polymorphisms in the FGF2 Gene and Risk of Serous Ovarian Cancer: Results From the Ovarian Cancer Association Consortium. (19456219)Johnatty S.E.... Chenevix-Trench G.2009FGF2, FGF13
12RUNX3 gene methylation in epithelial ovarian cancer t issues and ovarian cancer cell lines. (19645591)Zhang S.... Yu H.2009RUNX3
13Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer. (18165636)Chetrit A.... Sadetzki S.2008BRCA1, BRCA2
14Ovarian cancer immuno-reactive antigen domain contain ing 1 (OCIAD1), a key player in ovarian cancer cell adhesion. (18328549)Sengupta S.... Ganapathi R.2008PIK3CG, OCIAD1, DYT10
15'BRCAness' syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations. (18955455)Tan D.S.... Gore M.E.2008BRCA1, BRCA2
16Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasion. (17960624)Coffelt S.B.... Scandurro A.B.2008CAMP
17Protein expression levels of carcinoembryonic antigen (CEA) in Danish ovarian cancer patients: from the Danish 'MALOVA'ovarian cancer study. (18604735)Hogdall E.V.... Hogdall C.K.2008CEACAM3
18Expression of CD40 in ovarian cancer and adenovirus-mediated CD40 ligand therapy on ovarian cancer in vitro. (18705404)Jiang E.... Zhao X.2008CD40
19Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis. (18219286)Pearce C.L.... Berchuck A.2008PGR, NR3C1
20Prognostic value of estrogen receptor and progesterone receptor tumor expression in Danish ovarian cancer patients: from the 'MALOVA' ovarian cancer study. (17914554)HA... Kjaer S.K.2007PGR, ESR1
21Expression level of Wilms tumor 1 (WT1) protein has limited prognostic value in epithelial ovarian cancer: from the Danish 'MALOVA' ovarian cancer study. (17540436)Hogdall E.V.... Hogdall C.K.2007WT1
22Ovarian cancer at young age: the contribution of mismatch-repair defects in a population-based series of epithelial ovarian cancer before age 40. (17343610)Domanska K.... Nilbert M.2007BRCA1, BRCA2
23Characterization of ovarian cancer ascites on cell invasion, proliferation, spheroid formation, and gene expression in an in vitro model of epithelial ovarian cancer. (17971902)Puiffe M.L.... Mes-Masson A.M.2007PLEC
24Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer. (17925548)Marsh S.... Brown R.2007GSTP1, TP53, MAPT
25RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model. (17634556)Mabuchi S.... Testa J.R.2007MYC, VEGFA, EIF4EBP1
26Specific inhibition of AKT2 by RNA interference results in reduction of ovarian cancer cell proliferation: increased expression of AKT in advanced ovarian cancer. (16584837)Noske A.... Denkert C.2007AKT2, AKT3
27Comparative evaluation of the treatment efficacy of s uberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lin es and primary ovarian cancer cells from patients. (16834771)Sonnemann J.... Beck J.F.2006CASP3
28P53 mutations in tissue from Danish ovarian cancer patients: from the Danish 'MALOVA' ovarian cancer study. (16183105)Hogdall E.V.... Hogdall C.K.2006TP53, CLEC3B
29Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer. (16971669)Bamias A.... Psyrri A.2006CTNNB1, DCC
30Cyclooxygenase-2 expression is higher in ovarian cancer tissue adjacent to endometriosis than in ovarian cancer without comorbid endometriosis. (16456945)Chou Y.C.... Yuan C.C.2006PTGS2, KRT7, KRT20
31Maspin expression is characteristic for cisplatin-sensitive ovarian cancer cells and for ovarian cancer cases of longer survival rates. (16633061)Surowiak P.... Lage H.2006SERPINB5
32In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer. (15907982)Brewer M.... Zou C.2005TP53, CASP3, CDKN1A
33Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin-epithelin precursor (GEP), a prosurvival factor for ovarian cancer. (16044162)Kamrava M.... Kohn E.C.2005CASP3, PARP1, GRN
34Expression of icb-1 gene is interferon-gamma inducible in breast and ovarian cancer cell lines and affects the IFN gamma-response of SK-OV-3 ovarian cancer cells. (16219472)Treeck O.... Ortmann O.2005THEMIS2
35Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry. (14668547)Werness B.A.... Piver M.S.2004BRCA1, BRCA2
36The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer. (12615725)Tanyi J.L.... Mills G.B.2003PPAP2B
37Awareness and concern about ovarian cancer among women at risk because of a family history of breast or ovarian cancer. (14586320)Andersen M.R.... McTiernan A.2003BRCA1, BRCA2
38Evaluation of a polymorphism in intron 2 of the p53 gene in ovarian cancer patients. From the Danish 'Malova' Ovarian Cancer Study. (12926080)Hogdall E.V.... Hogdall C.K.2003TP53
39Expression of aFGF and bFGF in ovarian cancer and their effect on ovarian cancer cell proliferation (14613644)Zhang Y.... Yu H.Y.2003FGF1
40Mutational analysis of BRCA1 and BRCA2 and clinicopathologic analysis of ovarian cancer in 82 ovarian cancer families: two common founder mutations of BRCA1 in Japanese population. (11595708)Sekine M.... Tanaka K.2001BRCA1, BRCA2
41DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells. (11531283)Ahluwalia A.... Nephew K.P.2001DNMT3B, DNMT1, DNMT3A
42The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes. (10486320)Gayther S.A.... Ponder B.A.J.1999BRCA1, BRCA2
43Peritoneal serous papillary carcinoma, a phenotypic variant of familial ovarian cancer: implications for ovarian cancer screening. (10203660)Karlan B.Y.... Platt L.D.1999BRCA2
44Characteristics and growth patterns of human peritoneal mesothelial cells: comparison between advanced epithelial ovarian cancer and non-ovarian cancer sources. (10643588)Zhang X.Y.... Barton D.P.1999EGF, VIM
45Oral contraceptives and the risk of hereditary ovarian cancer. Hereditary Ovarian Cancer Clinical Study Group. (9700175)Narod S.A.... Ponder B.A.1998BRCA2
46Peritoneal fluid from ovarian cancer patients stimulates MUC1 epithelial mucin expression in ovarian cancer cell lines. (9579577)Munster D.J.... McGuckin M.A.1998IL1B, IL8, IL4
47Founder BRCA1 and BRCA2 mutations in Ashkenazi Jews in Israel: frequency and differential penetrance in ovarian cancer and in breast-ovarian cancer families. (9150153)Levy-Lahad E.... Halle D.1997BRCA1, BRCA2
48Prevalence and contribution of BRCA1 mutations in bre ast cancer and ovarian cancer: results from three U.S. population-based case-co ntrol studies of ovarian cancer. (9042908)Whittemore A.S.... Itnyre J.1997BRCA1
49Field trial for the early detection of patients with ovarian cancer--discrimination of ovarian cancer patients by the statistical analysis using Mahalanobis' generalized distance (1372032)Kobayashi H.... Okada K.1992AFP, MUC16, PSG2
50Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. I. Correlation of receptor expression with prognostic factors in patients with ovarian cancer. (1992720)Berchuck A.... Bast R.C.1991EGFR

Expression for genes affiliated with Ovarian Cancer

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Ovarian Cancer

Pathways for genes affiliated with Ovarian Cancer

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36QIAGEN, 3Cell Signaling Technology, 20KEGG, 41Thomson Reuters, 37R&D Systems, 10EMD Millipore, 34PharmGKB
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Pathways related to ovarian cancer according to GeneDecks:

(show top 50)    (show all 332)
idPathwayScoreTop Affiliating Genes
1Tec Kinases Signaling3631.1PIK3R3, PIK3R1, KITLG, VEGFC, MYD88, BMP1
2Cell Cycle / Checkpoint Control325.3KIF11, PCNA, PCM1, BUB1B, RB1, NBN
3p53 Mediated Apoptosis3625.1PIK3R3, PIK3R1, KIT, KITLG, VEGFC, BMP1
4eNOS Signaling3623.1PIK3R3, PIK3R1, KIT, KITLG, BMP1, BMP2
5Nuclear Receptor Activation by Vitamin-A3622.4NCOA1, NCOA3, KIT, KITLG, VEGFC, BMP1
6Glucocorticoid Receptor Signaling3622.1NCOA1, NCOA3, NCOR1, NCOR2, BMP1, BMP2
7Toxoplasmosis2019.2PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, RELA
8p53 signaling pathway2018.9SFN, SERPINB5, SERPINE1, CHEK1, CHEK2, BAX
9Small cell lung cancer2018.9PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, RELA
10Chagas disease (American trypanosomiasis)2018.6PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, RELA
11BRCA1 Pathway3617.7RB1, RBBP8, BRCA1, BRCA2, RAD51, RAD50
12Translation_Non-genomic (rapid) action of Androgen Receptor4117.6PIK3CA, PIK3R1, RELA, RELB, RAF1, MTOR
13Apoptosis Signaling Pathways3716.8SFN, BIRC2, BIRC3, BIRC5, BCL2, BCL2L1
14Non-small cell lung cancer2016.7PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, RB1
15Immune response_IL-2 activation and signaling pathway4116.6PIK3CB, PIK3CA, PIK3R1, RELA, RELB, MYC
16Development_Prolactin receptor signaling4116.4PIK3CB, PIK3CA, PIK3R1, RELA, MYC, RAF1
17Apoptosis and survival_Role of CDK5 in neuronal death and survival4116.3PIK3CB, PIK3CA, PIK3R1, RAF1, BCL2, BAD
18Acute myeloid leukemia2016.3PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, KIT
19Transcription_PPAR Pathway4116.2PIK3CB, PIK3CA, PIK3R3, PIK3R1, NCOA1, NCOR1
20Development Endothelin-1/EDNRA signaling1015.8PIK3CB, PIK3CA, PIK3R3, PIK3R1, RAF1, RAC1
21Immune response_IFN gamma signaling pathway4115.7PIK3CB, PIK3CA, PIK3R3, PIK3R1, BRCA1, MYC
22TNF Signaling3615.7BIRC2, BIRC3, CHUK, ATF3, ATF6, ATF1
23Progesterone-mediated oocyte maturation2015.7PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, BUB1
24Development Growth hormone signaling via PI3K/AKT and MAPK cascades1015.6PIK3CA, PIK3R1, RAF1, MTOR, ATF2, JUN
25Cell cycle Cell cycle (generic schema)1015.4RB1, RBL2, RBL1, CDK6, CDK2, CDC25C
26Apoptosis and survival_TNFR1 signaling pathway4115.4RELA, RELB, BIRC2, BIRC3, BCL2, CHUK
27Development Ligand-independent activation of ESR1 and ESR21015.3PIK3CA, PIK3R3, PIK3R1, NCOA1, NCOA3, IRS1
28Immune response_IL-4 signaling pathway4115.2PIK3CB, PIK3CA, PIK3R3, PIK3R1, RELA, RELB
29Development ERBB-family signaling1015.2PIK3CB, PIK3R3, PIK3R1, RELA, RELB, MYC
30Immune response_IL-1 signaling pathway4115.1RELA, SERPINE1, MYD88, CHUK, UBC, ATF2
31Selected targets of GCR-alpha1015.0KITLG, LEP, CGA, CFL1, FSHB, CDKN1A
32Development VEGF signaling and activation1014.7PIK3CB, PIK3CA, PIK3R3, PIK3R1, RELA, RELB
33Development VEGF signaling via VEGFR2 - generic cascades1014.6PIK3CB, PIK3CA, PIK3R3, PIK3R1, RELA, VEGFA
34Apoptosis and survival_Lymphotoxin-beta receptor signaling4114.5RELA, RELB, VCAM1, BIRC2, CHUK, BAX
35Transcription Role of VDR in regulation of genes involved in osteoporosis1014.1VDR, CGA, JUN, CDX2, CDKN1C, FOS
36Transcription_Role of VDR in regulation of genes involved in osteoporosis4113.8VDR, CGA, JUN, CDX2, CDKN1C, FOS
37Apoptosis and survival_Anti-apoptotic action of membrane-bound ESR14112.8PIK3CB, PIK3R1, BAD, MAP2K2, MAP2K4, MAPK3
38Apoptosis and survival Role of CDK5 in neuronal death and survival1012.6BCL2, BAD, APAF1, CASP9, AKT3, ERBB3
39EGFR Inhibitor Pathway, Pharmacodynamics3411.4CAMK2D, HRAS, NRG3, NFKB2, KRAS
40Apoptosis and survival Anti-apoptotic action of membrane-bound ESR11011.1MAP3K5
41IL-2 Pathway36INFPIK3R3, PIK3R1, MYC, RAF1, CHUK, JUN
42p38 Signaling36INFKIT, KITLG, VEGFC, BMP1, BMP2, BMP4
43Rap1 Pathway36INFKITLG, BRAF, VEGFC, BMP1, BMP2, BMP4
44NGF Pathway36INFPIK3R3, PIK3R1, BRAF, MYC, RAF1, RAC1
45PAK Pathway36INFPIK3R3, PIK3R1, KIT, KITLG, VEGFC, MYO18B
46PEDF Induced Signaling36INFRELA, SERPINF1, BRAF, BMP1, BMP2, BMP4
47eIF2 Pathway36INFPIK3R3, PIK3R1, KIT, KITLG, BRAF, VEGFC
48TGF-Beta Pathway36INFPIK3R3, PIK3R1, KITLG, VEGFC, BMP1, BMP2
49EGF Pathway36INFPIK3R3, PIK3R1, BRAF, MYC, RAF1, RAB5A
50P2Y Receptor Signaling36INFPIK3R3, PIK3R1, KIT, BRAF, VEGFC, MYC

Compounds for genes affiliated with Ovarian Cancer

about this section
Sources:
32Novoseek , 34PharmGKB, 9DrugBank, 18HMDB, 42Tocris Bioscience
See all sources

Compounds related to ovarian cancer according to GeneDecks:

(show top 50)    (show all 464)
idCompoundScoreTop Affiliating Genes
1atp32 54.9PIK3CB, PIK3CA, NCAM1, RECK, SGCB, KIT
2paclitaxel32 34 9 9 53.3PIK3CA, PIK3CG, KIT, KITLG, KIF11, PCNA
3cholesterol32 9 18 9 47.7PIK3CB, PIK3CA, PIK3R1, LRP1, NCOA1, RECK
4glucose32 30.7KIT, KISS1, SETD2, SERPINF1, NAGA, BRAF
5retinoid32 29.7NCOA1, NCOA3, NCOR1, NCOR2, RBP4, RBP1
6resveratrol32 9 18 9 31.9PIK3CA, PIK3CG, PCNA, RB1, BSG, BRCA1
7fatty acid32 28.0LRP1, NCOA1, RECK, SFN, RBP4, RBP1
8troglitazone32 42 9 9 28.1PIK3CG, RB1, SELE, SERPINE1, VDR, VCAM1
9ethanol32 34 9 18 9 29.1NCAM1, KITLG, RBP1, SERPINA1, VAT1, BMP7
10bromodeoxyuridine32 24.8PIK3CA, PIK3R1, NCAM1, NCOA3, KITLG, PCNA
11valine32 22.6KIT, RBP4, VIM, VIP, BRAF, RAF1
12irinotecan32 34 9 9 24.5KIT, BRAF, VEGFA, PARP1, BCL2L1, CHEK1
13formaldehyde32 18 21.9KIT, VWF, PCNA, RB1, SELE, VIM
14potassium32 9 18 9 23.4PIK3CA, NCAM1, SGCB, SGK1, KITLG, VTN
15pdtc32 20.1PIK3CA, PIK3CG, SELE, SETD2, SERPINB5, VCAM1
161,25 dihydroxy vitamin d332 20.1NCOA1, RB1, VDR, MYC, BMP2, BMP6
17trastuzumab32 34 9 9 23.1PIK3CA, PIK3R1, PIK3CG, KIT, VEGFC, RAF1
18acth32 19.8SERPINA6, SERPINA1, VIP, PBX1, LHCGR, LEP
19vinblastine32 9 9 21.1BUB1B, VIM, RAF1, BIRC5, KDR, BCL2
20progestins32 18.5SERPINA6, LIF, PAEP, S100A6, JAK2, MMP3
21sucrose32 9 18 9 21.1LRP1, RECK, RBP4, BSG, RAD51, RARA
22sterol32 17.6PIK3R1, LRP1, RBP1, LIPE, BLZF1, SCD
23ionomycin32 17.3PIK3CB, SETD2, RAG1, BCL10, KCNMA1, CHUK
24deoxyribonucleic acid32 17.0PCNA, NAT2, LMNA, BMP2, BMP4, BMP7
25raloxifene32 9 9 19.0NCOA1, NCOA3, VWF, SERPINC1, SERPINE1, VDR
26diethylstilbestrol32 9 9 18.8NCOA1, CGA, CGB5, FST, ITGB3, AR
27betacarotene32 16.8VWF, PCNA, RB1, RBP4, RBP1, NAT2
28leukotriene b432 42 18 18.7RAC1, LCN2, MPO, MMP9, FPR2, GUSB
295-hydroxytryptamine32 16.5SGCB, SERPINE1, VIM, VIP, BMP6, RAF1
303-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide32 16.3PCNA, MYC, PARP1, BCL2, BCL2L1, BAX
31roscovitine32 16.1PIK3CG, PCNA, VIM, BIRC5, PARP1, BCL2L1
32cytosine32 18 16.9SERPINB5, SERPINB2, BRCA1, RAD51, RASSF1, LCP1
33uric acid32 18 16.7RBP4, SERPINE1, LGALS1, LEP, CHKA, MTHFR
34triptolide32 15.5VEGFA, BIRC3, PARP1, BCL2, BAX, JUN
35ns 39832 42 16.2PIK3CG, PCNA, PARP1, CDKN1B, MMP1, FGF2
36dithiothreitol32 15.1VWF, SERPINB2, KCNMA1, UGT1A1, LALBA, ATF6
37mevalonate32 15.1SERPINE1, VCAM1, BMP2, RAB5A, RAC1, BCL2L1
38rituximab32 34 9 9 18.0RAF1, BIRC2, BIRC5, BCL2, BCL2L1, YY1
39ethidium bromide32 14.7VWF, VTN, MYCN, RAD51, BIRC5, PARP1
40vincristine32 34 9 9 17.6NCAM1, RECK, KIT, MYCN, UGCG, CGB
41cerivastatin32 9 9 16.2SERPINE1, BMP2, RAC1, MMP1, APOA1, APOB
42b 72332 14.2PCNA, VIM, CHKA, MUC1, MUC16, S100A1
43palmitate32 14.2SELE, SCD, UCP1, S100A6, ATF3, IRS1
44phenethyl isothiocyanate32 14.0MYC, PARP1, BCL2, BCL2L1, BAX, JUN
45tarc32 13.9CDH1, IL10, IL13, IL18, IL1A, IL4
46sodium nitroprusside32 13.8SGCB, VWF, PCNA, VIP, BMP6, KCNMA1
47ursodeoxycholic acid32 9 18 9 16.8PCNA, BMP6, LBR, MKI67, APOE, GPT
48sp 60012532 42 14.7PIK3CG, VCAM1, BIRC2, BIRC3, CDKN1A, CD40
49mycophenolate mofetil32 9 9 14.6SELE, SERPINE1, UGT1A1, CD79A, CD36, CD40
50gtp32 INFPIK3CA, PIK3R1, RECK, SGCB, VIP, BRAF

GO Terms for genes affiliated with Ovarian Cancer

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Sources:
12Gene Ontology
See all sources

Cellular components related to ovarian cancer according to GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1nucleusGO:00563491.8ZNF350, ZNF354A, ZNF23, ZNF318, PIK3CB, LRP1
2cytoplasmGO:00573778.3ZNF318, PIK3CG, LRP1, KLF6, RGCC, NCOA3
3cytosolGO:00582962.2PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, NCF1
4nucleoplasmGO:00565447.3ZNF217, NCOA1, NCOA3, NCOR1, NCOR2, RELA
5extracellular regionGO:00557646.9NCAM1, CNTN4, KISS1, KITLG, VWF, VTN
6extracellular spaceGO:00561544.9KIT, KITLG, VTN, SFN, SFRP5, PCSK6
7integral to plasma membraneGO:00588736.5LRP1, SGCB, BST2, LPAR1, LPAR2, LPAR3
8nucleolusGO:00573034.2ZNF350, ZNF318, RGCC, NCOA3, NCOR2, PDCD4
9membraneGO:01602024.8PIK3CG, RECK, PCSK6, SELENBP1, SEMA3B, SEMA3F
10cell surfaceGO:00998624.5NCAM1, KISS1R, PCSK6, BST2, VEGFA, LPAR1
11perinuclear region of cytoplasmGO:04847123.5BUB1B, SELE, SERBP1, SET, LMNA, MYO6
12transcription factor complexGO:00566717.9RELA, RBL2, PARP1, ZEB1, YY1, LBX1
13external side of plasma membraneGO:00989716.8NCAM1, KIT, VWF, VCAM1, KDR, LAG3
14extracellular matrixGO:03101216.4VWF, VTN, PCSK6, SERPINF1, SERPINE1, VCAN
15membrane raftGO:04512115.8SELE, BSG, BST2, RAB5A, PAG1, BCL10
16caveolaGO:00590113.2SELE, BMPR1A, BMPR2, LIPE, KCNMA1, SCN5A
17plasma membraneGO:005886INFPIK3R1, PIK3CG, KLB, NCAM1, PDCD1, RECK

Biological processes related to ovarian cancer according to GeneDecks:

(show top 50)    (show all 96)
idNameGO IDScoreTop Affiliating Genes
1signal transductionGO:00716541.0PIK3CB, PDCD1, KIT, KITLG, SFN, SFRP5
2positive regulation of transcription from RNA polymerase II promoterGO:04594435.5KLF6, NCOA1, NCOA3, RELA, RB1, RBL1
3apoptotic processGO:00691534.2PDCD1, PDCD4, SGK1, SFN, SFRP5, BUB1
4small molecule metabolic processGO:04428133.8PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, NCOA1
5positive regulation of transcription, DNA-dependentGO:04589331.2KLF6, NCOA1, NCOA3, NCOA4, RELA, REST
6negative regulation of transcription from RNA polymerase II promoterGO:00012228.6KLF10, NCOR1, NCOR2, REST, RBBP8, VHL
7response to drugGO:04249325.3NBN, VEGFC, MYC, RAD54L, LIPE, BCL2
8negative regulation of transcription, DNA-dependentGO:04589224.6ZNF350, ZNF217, PDCD4, RELA, REST, RB1
9DNA repairGO:00628124.4PCNA, RBBP8, NBN, BRCA1, BRCA2, RAD51
10cell adhesionGO:00715522.9NCAM1, CNTN6, KITLG, VWF, VTN, VCAM1
11cell-cell signalingGO:00726722.7KLF10, SEMA3B, BST2, NAMPT, BMP2, LALBA
12innate immune responseGO:04508722.5PIK3CG, NCF1, RELA, SERPING1, BST2, MYD88
13protein phosphorylationGO:00646820.9SGK1, BRAF, BMPR1A, BMPR1B, RARA, RAF1
14transcription initiation from RNA polymerase II promoterGO:00636720.7NCOR1, NCOR2, RBL1, SERPINE1, VDR, MYC
15cell cycle arrestGO:00705019.6RB1, NBN, MYC, RASSF1, BARD1, MSH2
16axon guidanceGO:00741119.3NCAM1, CNTN4, CNTN6, SEMA3B, SEMA3F, BOC
17nerve growth factor receptor signaling pathwayGO:04801119.3PIK3CB, PIK3CA, PIK3R1, RELA, PCSK6, BRAF
18transforming growth factor beta receptor signaling pathwayGO:00717919.1KLF10, NCOR1, NCOR2, RBL1, SERPINE1, MYC
19G1/S transition of mitotic cell cycleGO:00008218.3PCNA, RB1, BCL2, UBC, CDK6, CDKN1A
20positive regulation of gene expressionGO:01062817.7NCOA3, RELB, KIT, BRAF, VEGFA, VDR
21response to organic cyclic compoundGO:01407017.6SERPINA1, BMP4, UGT1A1, MSH2, ATF1, JUN
22positive regulation of angiogenesisGO:04576617.5SERPINE1, VEGFA, KDR, CHI3L1, MTDH, CD34
23positive regulation of protein phosphorylationGO:00193417.3RB1CC1, VEGFA, BMP2, BMP4, MTOR, AXIN2
24response to estradiol stimulusGO:03235517.2NCOA1, SERPINA1, BRCA2, VDR, BMP4, RARA
25epidermal growth factor receptor signaling pathwayGO:00717316.6PIK3CA, PIK3R1, RAF1, PAG1, CHUK, UBC
26heart developmentGO:00750716.6PCNA, RBP4, RB1CC1, VCAM1, VCAN, BMP2
27fibroblast growth factor receptor signaling pathwayGO:00854316.4PIK3CA, PIK3R1, KLB, BRAF, RAF1, CHUK
28phosphatidylinositol-mediated signalingGO:04801516.2PIK3CB, PIK3CA, PIK3R1, PCNA, BUB1B, CHUK
29positive regulation of ERK1 and ERK2 cascadeGO:07037416.1BRAF, BMP2, BMP4, KDR, CHI3L1, S100A7
30response to lipopolysaccharideGO:03249615.9SELE, SERPINA1, UGT1A1, S100A7, JUN, JAK2
31positive regulation of endothelial cell proliferationGO:00193815.7VEGFA, BMP2, BMP4, BMP6, BMPR2, KDR
32platelet degranulationGO:00257615.6VWF, SERPINA1, SERPINE1, SERPING1, VEGFA, VEGFC
33female pregnancyGO:00756515.6LIPE, CLDN4, PAPPA, BCL2, LEP, FSHB
34positive regulation of protein kinase B signaling cascadeGO:05189715.5PIK3CG, CHI3L1, MTDH, MTOR, AXL, INS
35agingGO:00756815.5SERPINF1, VDR, VCAM1, FURIN, JUN, ASS1
36G1 phase of mitotic cell cycleGO:00008015.4RB1, RBL2, RBL1, UBC, CDK6, CDKN1A
37toll-like receptor 4 signaling pathwayGO:03414215.3RELA, MYD88, CHUK, UBC, ATF1, ATF2
38response to glucocorticoid stimulusGO:05138415.3SERPINF1, SERPINE1, INSR, IL10, IL1B, IL1RN
39toll-like receptor signaling pathwayGO:00222415.3RELA, MYD88, BCL10, CHUK, UBC, ATF1
40MyD88-dependent toll-like receptor signaling pathwayGO:00275515.0RELA, MYD88, CHUK, UBC, ATF1, ATF2
41toll-like receptor 3 signaling pathwayGO:03413815.0RELA, CHUK, UBC, ATF1, ATF2, JUN
42TRIF-dependent toll-like receptor signaling pathwayGO:03566615.0RELA, CHUK, UBC, ATF1, ATF2, JUN
43cellular response to mechanical stimulusGO:07126014.9MYD88, BCL10, CHEK1, BAD, CD40, ITGB1
44positive regulation of peptidyl-serine phosphorylationGO:03313814.9PIK3CA, BRAF, VEGFA, RAF1, LIF, PAK1
45MyD88-independent toll-like receptor signaling pathwayGO:00275614.8RELA, CHUK, UBC, ATF1, ATF2, JUN
46toll-like receptor 1 signaling pathwayGO:03413014.7RELA, MYD88, CHUK, UBC, ATF1, ATF2
47toll-like receptor 2 signaling pathwayGO:03413414.7RELA, MYD88, CHUK, UBC, ATF1, ATF2
48response to woundingGO:00961114.7VWF, RAC1, FN1, FGF7, MET, MDK
49positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406814.5KIT, KDR, JAK2, FLT1, INS, FGFR1
50positive regulation of fibroblast proliferationGO:04814614.5MYC, BMI1, LIG4, XRCC4, S100A6, JUN

Molecular functions related to ovarian cancer according to GeneDecks:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1ATP bindingGO:00552439.8PIK3CB, PIK3CA, PIK3CG, SGK1, KIT, KIF11
2sequence-specific DNA binding transcription factor activityGO:00370031.6ZNF217, KLF10, KLF6, RELA, RELB, REST
3protein homodimerization activityGO:04280326.1KIT, VWF, BST2, NAGA, VEGFA, MYOCD
4sequence-specific DNA bindingGO:04356523.3NANOG, VDR, MYC, RAG1, RARA, RARB
5protein kinase bindingGO:01990121.6RGCC, RELA, KIF11, RB1CC1, VIM, LIPE
6transcription factor bindingGO:00813421.4RELA, REST, RB1, RBL1, NBN, VHL
7growth factor activityGO:00808321.0KITLG, VEGFA, VEGFC, BMP1, BMP2, BMP4
8identical protein bindingGO:04280220.7RELA, PCNA, PCM1, VIM, MYD88, RAD51
9enzyme bindingGO:01989920.6NCOA1, BRCA1, VHL, RARA, RAC1, BLZF1
10receptor bindingGO:00510220.5SERPINE1, BMP2, RARA, LIF, PANX1, MSN
11cytokine activityGO:00512519.0KITLG, NAMPT, VEGFA, BMP1, BMP2, BMP4
12protein kinase activityGO:00467217.9PIK3CG, BUB1, BUB1B, BRAF, RAF1, PAK1
13transcription regulatory region DNA bindingGO:04421217.2ZNF217, NCOR1, RELA, REST, BRCA1, PAX8
14hormone activityGO:00517914.4VIP, LEP, CGA, CGB, FSHB, INHA
15protein bindingGO:005515INFZNF350, ZNF217, PIK3CB, PIK3CA, PIK3R1, PIK3CG

Sources for Ovarian Cancer

about this section
2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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