MCID: OVR042
MIFTS: 85

Ovarian Cancer malady

Rare diseases, Cancer diseases, Reproductive diseases categories
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Summaries for Ovarian Cancer

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MedlinePlus:33 The ovaries are part of the female reproductive system. they produce a woman's eggs and female hormones. each ovary is about the size and shape of an almond. cancer of the ovary is not common, but it causes more deaths than other female reproductive cancers. the sooner ovarian cancer is found and treated, the better your chance for recovery. but ovarian cancer is hard to detect early. women with ovarian cancer may have no symptoms or just mild symptoms until the disease is in an advanced stage. then it is hard to treat. symptoms may include a heavy feeling in the pelvis pain in the lower abdomen bleeding from the vagina weight gain or loss abnormal periods unexplained back pain that gets worse gas, nausea, vomiting, or loss of appetite to diagnose ovarian cancer, doctors do one or more tests. they include a physical exam, a pelvic exam, lab tests, ultrasound, or a biopsy. treatment is usually surgery followed by chemotherapy. nih: national cancer institute

MalaCards based summary: Ovarian Cancer, also known as ovarian carcinoma, is related to breast cancer and adenocarcinoma. An important gene associated with Ovarian Cancer is RRAS2 (related RAS viral (r-ras) oncogene homolog 2), and among its related pathways are Development EGFR signaling pathway and Ras signaling pathway. The drugs chlorambucil and cisplatin and the compounds agar and paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include the ovary, breast and ovary, and related mouse phenotypes are tumorigenesis and cellular.

Disease Ontology:8 A female reproductive organ cancer that is located in the ovary.

CDC:3 Cancer is a disease in which cells in the body grow out of control. Cancer is always named for the part of the body where it starts, even if it spreads to other body parts later.

Novus Biologicals:45 Tumor markers can be found in the body when cancer is present. They are most often found in the blood or urine, but can also be found in tumors and other tissues. High level of the tumor marker CA125 in the blood strongly suggests ovarian cancer. CA125 is an antigen present on 80% of non-mucinous ovarian carcinomas.

Wikipedia:65 Ovarian cancer is a cancer that begins in an ovary. This is the result of the development of abnormal... more...

Description from OMIM:46 167000

Aliases & Classifications for Ovarian Cancer

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Ovarian Cancer, Aliases & Descriptions:

Name: Ovarian Cancer 8 42 46 10 44 33
Ovarian Carcinoma 8 42 46 44
Tumor of the Ovary 8 62
Ovarian Neoplasm 8 62
Ovary Neoplasm 8 22
Ovarian Cancer, Susceptibility to 9
 
Malignant Neoplasm of Ovary 62
Malignant Tumour of Ovary 8
Epithelial Ovarian Cancer 62
Malignant Ovarian Tumor 8
Primary Ovarian Cancer 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Reproductive diseases


Related Diseases for Ovarian Cancer

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Diseases in the Ovarian Cancer family:

Ovarian Benign Neoplasm

Diseases related to Ovarian Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 348)
idRelated DiseaseScoreTop Affiliating Genes
1breast cancer31.8CDH1, RRAS2, BARD1, AKT1, PIK3CA, MUC16
2adenocarcinoma31.7MUC16, PIK3CA, CTNNB1, CDH1, AKT1, BRCA1
3colorectal cancer31.6MUC16, AKT1, CTNNB1, BRCA2, CDH1, PIK3CA
4peritoneal carcinoma31.5BRCA2, BRCA1
5fallopian tube cancer31.5BRCA1, BRCA2
6ovarian cancer, somatic31.4CTNNB1, PIK3CA, AKT1
7lynch syndrome31.4BRCA1, BRCA2
8brca1 and brca2 hereditary breast and ovarian cancer31.4BRCA1, BRCA2
9dysgerminoma31.4BRCA1, BRCA2
10lung cancer31.3PIK3CA, BRCA2, CDH1, MUC16, AKT1
11endometrial carcinoma31.2MUC16, CDH1, CTNNB1
12prostate cancer31.2BRCA1, MUC16, BRCA2, AKT1, CTNNB1, CDH1
13breast-ovarian cancer, familial, 131.2BRCA2
14bilateral breast cancer31.1BRCA1, BRCA2
15papillary carcinoma31.1BRCA2, MUC16, CDH1
16male breast cancer31.0BRCA2, BRCA1
17ovarian cystadenoma31.0MUC16, BRCA1
18pancreatic cancer31.0BRCA2, AKT1, CDH1
19cystadenocarcinoma31.0MUC16
20retinoblastoma31.0PIK3CA, BRCA2, BRCA1, AKT1
21ataxia telangiectasia30.8BRCA1, BRCA2, PIK3CA
22melanoma30.8BRCA2, CTNNB1, CDH1, AKT1, PIK3CA
23li-fraumeni syndrome30.8BRCA1, BRCA2
24ovarian serous cystadenocarcinoma30.7MUC16
25endodermal sinus tumor10.9
26leydig cell tumor10.9
27peritonitis10.8
28endotheliitis10.8
29germ cell tumors10.8
30hereditary breast ovarian cancer10.8
31sertoli-leydig cell tumor10.8
32mixed germ cell tumor10.7
33ductal carcinoma in situ10.7CDH1, BRCA1, BRCA2
34hypoxia10.7
35cowden disease10.7PIK3CA, BRCA1, BRCA2
36gastric adenocarcinoma10.7CTNNB1, CDH1, MUC16, PIK3CA
37goblet cell carcinoid10.7CDH1, CTNNB1
38colorectal cancer, somatic10.6AKT1, PIK3CA, CTNNB1
39thyroid cancer, anaplastic10.6PIK3CA, CDH1, CTNNB1
40medulloblastoma10.6PIK3CA, BRCA2, CTNNB1, AKT1
41lung adenocarcinoma10.6CTNNB1, MUC16, PIK3CA, CDH1
42non-small cell lung carcinoma10.6CTNNB1, AKT1, MUC16, PIK3CA, CDH1
43hepatocellular carcinoma, somatic10.6CTNNB1, PIK3CA
44endometriosis10.6
45stomach cancer10.6CTNNB1, PIK3CA, CDH1, AKT1
46familial adenomatous polyposis10.6CDH1, CTNNB1, BRCA1
47liver cancer10.6CDH1, PIK3CA, CTNNB1, BRCA2, AKT1
48familial colorectal cancer10.6BRCA1, BRCA2
49tongue squamous cell carcinoma10.6CDH1, CTNNB1, MUC16, AKT1, PIK3CA
50prostatitis10.6

Graphical network of the top 20 diseases related to Ovarian Cancer:



Diseases related to ovarian cancer

Symptoms for Ovarian Cancer

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Clinical features from OMIM:

167000

Drugs & Therapeutics for Ovarian Cancer

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Genetic Tests for Ovarian Cancer

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Genetic tests related to Ovarian Cancer:

id Genetic test Affiliating Genes
1 Neoplasm of Ovary22

Anatomical Context for Ovarian Cancer

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MalaCards organs/tissues related to Ovarian Cancer:

32
Breast, Ovary, Testes, Endothelial, Lung, Lymph node, T cells, Liver, Prostate, Colon, Bone, Monocytes, Neutrophil, Bone marrow, Testis, Pituitary, Brain, Thyroid, Appendix, Eye, Spleen, Heart, Smooth muscle, Uterus, Myeloid, Nk cells

FMA organs/tissues related to Ovarian Cancer:

14
The ovary

Animal Models for Ovarian Cancer or affiliated genes

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Publications for Ovarian Cancer

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Articles related to Ovarian Cancer:

(show top 50)    (show all 5097)
idTitleAuthorsYear
1
An Analysis of Polymorphisms Within the Wnt Signaling Pathway in Relation to Ovarian Cancer Risk in a Polish Population. (24078348)
2013
2
A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first. (24137335)
2013
3
miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells. (23045278)
2013
4
TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells. (23357533)
2013
5
Hope, quality of life, and benefit from treatment in women having chemotherapy for platinum-resistant/refractory recurrent ovarian cancer: the gynecologic cancer intergroup symptom benefit study. (24107972)
2013
6
RNF43 mutations are recurrent in Chinese patients with mucinous ovarian carcinoma but absent in other subtypes of ovarian cancer. (24001777)
2013
7
PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. (23340297)
2013
8
Nerve growth factor stimulates cellular proliferation of human epithelial ovarian cancer. (22411587)
2012
9
Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-I_B activation. (22228447)
2012
10
Sodium arsenite A+ hyperthermia sensitizes p53-expressing human ovarian cancer cells to cisplatin by modulating platinum-DNA damage responses. (22331493)
2012
11
Matrix metalloproteinase-9 expression correlates with prognosis and involved in ovarian cancer cell invasion. (22832979)
2012
12
Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells. (22465665)
2012
13
Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2. (22396544)
2012
14
BRCA1 is both a prognostic and predictive biomarker of response to chemotherapy in sporadic epithelial ovarian cancer. (21920589)
2011
15
An exploration of the communication preferences regarding genetic testing in individuals from families with identified breast/ovarian cancer mutations. (20878485)
2011
16
37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells. (21193558)
2011
17
The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer. (21451362)
2011
18
Jagged1 expression regulated by Notch3 and Wnt/I^-catenin signaling pathways in ovarian cancer. (20953350)
2010
19
Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer. (20118984)
2010
20
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. (20852632)
2010
21
The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells. (19147209)
2009
22
Reproductive and hormonal factors, and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: results from the International BRCA1/2 Carrier Cohort Study. (19190154)
2009
23
A novel BRCA1 mutation in a Spanish patient with ovarian cancer. (18278587)
2009
24
Identification of suitable reference genes for gene expression studies of human serous ovarian cancer by real-time polymerase chain reaction. (19622337)
2009
25
Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis. (19208843)
2009
26
Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents. (18187487)
2008
27
A case of ovarian cancer associated with hypercalcemia. (18845526)
2008
28
Combined staining of TAG-72, MUC1, and CA125 improves labeling sensitivity in ovarian cancer: antigens for multi-targeted antibody-guided therapy. (17478446)
2007
29
Yang,C.Q., Chan,K.Y.K., Ngan,H.Y.S., Khoo,U.S., Chiu,P.M., Chan,Q.K.Y., Xue,W.C., and Cheung,A.N.Y. Single nucleotide polymorphisms of follicle-stimulating hormone receptor are associated with ovarian cancer susceptibility. Carcinogenesis, July 2006; 27, 1502 1506. (17307804)
2007
30
TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients. (17488735)
2007
31
Peritoneal tuberculosis mimicking advanced ovarian cancer: a retrospective review of 22 cases. (16740297)
2006
32
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells. (17088436)
2006
33
PIK3CA mutations in ovarian cancer. (16203798)
2005
34
Transforming growth factor-beta1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells. (14676209)
2004
35
Activity of telomerase and extracellular regulated protein kinases in parental and drug resistant cells of leukemia and ovarian cancer. (15228655)
2004
36
Mechanisms regulating the constitutive activation of the extracellular signal-regulated kinase (ERK) signaling pathway in ovarian cancer and the effect of ribonucleic acid interference for ERK1/2 on cancer cell proliferation. (15243131)
2004
37
Carrier risk status changes resulting from mutation testing in hereditary non-polyposis colorectal cancer and hereditary breast-ovarian cancer. (12920070)
2003
38
Molecular determinants of epothilone B derivative (BMS 247550) and Apo-2L/TRAIL-induced apoptosis of human ovarian cancer cells. (12694652)
2003
39
Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. (12969782)
2003
40
Relationship between the expression of connexin 43 and bystander effect of suicide gene therapy in ovarian cancer]. (11769669)
2001
41
Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer. (11103784)
2000
42
Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells. (10702246)
2000
43
Mutation analysis of the Smad3 gene in human ovarian cancers. (10536178)
1999
44
Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model. (10473101)
1999
45
Expression analysis of protein kinase C isozymes and multidrug resistance associated genes in ovarian cancer cells. (9615708)
1998
46
Overexpression of the oncogene c-erbB-2 (HER2/neu) and response to chemotherapy in patients with ovarian cancer. (9475194)
1998
47
Clinical features of ovarian cancer in Japanese women with germ-line mutations of BRCA1. (9516977)
1998
48
Screening for ESR mutations in breast and ovarian cancer patients. (9195227)
1997
49
Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene. (8988179)
1997
50
A phase I/II study of dose-intense paclitaxel with cisplatin and cyclophosphamide as initial therapy of poor-prognosis advanced-stage epithelial ovarian cancer. (8751547)
1996

Variations for Ovarian Cancer

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Clinvar genetic disease variations for Ovarian Cancer:

6
id Gene Name Type Significance SNP ID Assembly Location
1PIK3CANM_006218.2(PIK3CA): c.3140A> G (p.His1047Arg)single nucleotide variantPathogenicrs121913279GRCh37Chr 3, 178952085: 178952085
2PIK3CANM_006218.2(PIK3CA): c.1633G> A (p.Glu545Lys)single nucleotide variantPathogenicrs104886003GRCh37Chr 3, 178936091: 178936091
3AKT1NM_001014431.1(AKT1): c.49G> A (p.Glu17Lys)single nucleotide variantPathogenicrs121434592GRCh37Chr 14, 105246551: 105246551

Expression for genes affiliated with Ovarian Cancer

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Expression patterns in normal tissues for genes affiliated with Ovarian Cancer

Search GEO for disease gene expression data for Ovarian Cancer.

Pathways for genes affiliated with Ovarian Cancer

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Pathways related to Ovarian Cancer according to GeneCards/GeneDecks:

(show all 49)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Development ERBB family signaling60
Development GDNF family signaling60
10.5PIK3CA, RRAS2, AKT1, CDH1, CTNNB1
2
Show member pathways
10.5PIK3CA, RRAS2, AKT1, CDH1, CTNNB1
3
Show member pathways
Signaling Pathways in Glioblastoma37
10.5PIK3CA, BRCA2, BRCA1, AKT1, CDH1, CTNNB1
410.5PIK3CA, RRAS2, AKT1, CTNNB1
5
Show member pathways
Integrin-mediated cell adhesion37
Focal Adhesion37
10.5PIK3CA, RRAS2, AKT1, CTNNB1
610.5PIK3CA, RRAS2, AKT1, CTNNB1
7
Show member pathways
10.5PIK3CA, RRAS2, AKT1
810.5PIK3CA, BRCA2, BRCA1, AKT1, CTNNB1
910.5CTNNB1, CDH1, AKT1, BRCA2, PIK3CA
10
Show member pathways
Prostate Cancer37
Integrated Cancer pathway37
Steroid Biosynthesis37
10.5PIK3CA, BRCA1, AKT1, BARD1
1110.5CTNNB1, CDH1, BARD1, AKT1, BRCA1, BRCA2
12
Show member pathways
10.5AKT1, BRCA2, PIK3CA
13
Show member pathways
IFN-gamma pathway37
10.5AKT1, BRCA1, PIK3CA
14
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades60
10.5AKT1, BRCA1, PIK3CA
15
Show member pathways
10.5CTNNB1, CDH1, AKT1, RRAS2
1610.5CTNNB1, CDH1, AKT1, RRAS2
17
Show member pathways
10.5CTNNB1, CDH1, AKT1, RRAS2
18
Show member pathways
Signal transduction PTEN pathway60
10.5PIK3CA, AKT1, CDH1, CTNNB1
1910.5CTNNB1, CDH1, AKT1, PIK3CA
2010.5CTNNB1, CDH1, AKT1, PIK3CA
2110.5PIK3CA, AKT1, CDH1
2210.5CDH1, AKT1, PIK3CA
2310.5CDH1, AKT1, PIK3CA
2410.5RRAS2, AKT1, CTNNB1
2510.5CTNNB1, AKT1, RRAS2
2610.5PIK3CA, AKT1, CTNNB1
2710.5PIK3CA, AKT1, CTNNB1
28
Show member pathways
Development A1 receptor signaling60
G protein signaling G Protein alpha q signaling cascades60
10.5PIK3CA, AKT1, CTNNB1
29
Show member pathways
Translation Non genomic rapid action of Androgen Receptor60
10.5PIK3CA, AKT1, CTNNB1
30
Show member pathways
VEGFR1 specific signals37
10.5PIK3CA, AKT1, CTNNB1
31
Show member pathways
10.5PIK3CA, AKT1, CTNNB1
32
Show member pathways
Development A2B receptor action via G protein alpha s60
10.5CTNNB1, AKT1, PIK3CA
3310.5PIK3CA, SEPT9, CDH1, CTNNB1
3410.5PIK3CA, AKT1
3510.5PIK3CA, AKT1
3610.5AKT1, PIK3CA
3710.5AKT1, PIK3CA
38
Show member pathways
Angiogenesis37
10.5AKT1, PIK3CA
39
Show member pathways
10.5AKT1, PIK3CA
4010.5BRCA1, AKT1, CTNNB1
4110.5BRCA1, AKT1, CTNNB1
4210.5PIK3CA, CDH1, CTNNB1
43
Show member pathways
RAC1 signaling pathway37
10.5CTNNB1, CDH1, PIK3CA
44
Show member pathways
10.5CTNNB1, CDH1, PIK3CA
4510.5BARD1, BRCA1, BRCA2
46
Show member pathways
10.5BARD1, BRCA1, BRCA2
4710.5AKT1, CDH1, CTNNB1
4810.5AKT1, CDH1, CTNNB1
49
Show member pathways
10.5BRCA1, BRCA2

Compounds for genes affiliated with Ovarian Cancer

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Compounds related to Ovarian Cancer according to GeneCards/GeneDecks:

(show top 50)    (show all 69)
idCompoundScoreTop Affiliating Genes
1agar4411.0PIK3CA, RRAS2, BRCA1, AKT1, CDH1, CTNNB1
2paclitaxel44 50 1113.0PIK3CA, BRCA2, BRCA1, MUC16, AKT1, CDH1
3indole-3-carbinol4410.9CTNNB1, CDH1, AKT1, BRCA1, BRCA2
4tamoxifen44 50 28 1113.9PIK3CA, BRCA2, BRCA1, AKT1, CDH1, CTNNB1
5cisplatin44 50 61 1113.9PIK3CA, BRCA2, BRCA1, MUC16, AKT1, CDH1
6estrogen4410.9PIK3CA, BRCA2, BRCA1, MUC16, AKT1, BARD1
7adriamycin4410.9BRCA2, BRCA1, AKT1, CDH1, CTNNB1
8testosterone44 61 24 1113.9PIK3CA, BRCA2, BRCA1, MUC16, AKT1, CDH1
9genistein44 28 61 2 24 1115.9PIK3CA, BRCA2, BRCA1, AKT1, CDH1, CTNNB1
10doxorubicin44 50 1112.9PIK3CA, BRCA1, MUC16, AKT1, CDH1, CTNNB1
11paraffin4410.9BRCA2, BRCA1, MUC16, AKT1, CDH1, CTNNB1
12matrigel4410.9PIK3CA, BRCA2, AKT1, CDH1, CTNNB1
134-hydroxytamoxifen4410.9CTNNB1, AKT1, BRCA1, BRCA2
14gefitinib44 50 1112.9PIK3CA, AKT1, CDH1, CTNNB1
15etoposide44 50 61 1113.9PIK3CA, BRCA2, BRCA1, AKT1, CDH1
16adpribose4410.9CTNNB1, BRCA1, BRCA2, PIK3CA
17retinoic acid44 2411.9PIK3CA, BRCA2, BRCA1, AKT1, DPH1, CDH1
18sodium bisulfite4410.9CTNNB1, CDH1, BRCA1
19nocodazole44 1111.9BRCA1, AKT1, CDH1, CTNNB1
20h2o24410.9PIK3CA, BRCA2, BRCA1, MUC16, AKT1, CTNNB1
21progesterone44 28 61 24 1114.9PIK3CA, BRCA2, BRCA1, MUC16, CDH1, CTNNB1
22resveratrol44 61 24 1113.9CTNNB1, BRCA1, BRCA2, PIK3CA
23p0024410.9BRCA2, BRCA1, CDH1, CTNNB1
24docetaxel44 50 61 1113.9PIK3CA, BRCA2, BRCA1, CDH1
25gtp44 2811.9PIK3CA, SEPT9, RRAS2, AKT1, CTNNB1
26mg 13244 6111.9BRCA1, AKT1, CDH1, CTNNB1
27vegf4410.9PIK3CA, BRCA1, MUC16, AKT1, CDH1, CTNNB1
28crcs4410.9CTNNB1, CDH1, PIK3CA
29phosphatidylinositol4410.9PIK3CA, BRCA2, BRCA1, AKT1, CDH1, CTNNB1
30glutamine4410.8CTNNB1, CDH1, AKT1, BRCA1, BRCA2
315fluorouracil4410.8CTNNB1, CDH1, BRCA1, PIK3CA
32chlorophyllin4410.8CDH1, CTNNB1
33serine4410.8PIK3CA, RRAS2, BRCA1, MUC16, AKT1, CDH1
34phosphotyrosine4410.8CTNNB1, CDH1, BRCA1, PIK3CA
35leptomycin b44 6111.8BRCA1, CDH1, CTNNB1
36celecoxib44 61 28 50 24 1115.8CTNNB1, CDH1, AKT1
37ag 14784410.8PIK3CA, AKT1, CTNNB1
38tyrosine4410.8PIK3CA, RRAS2, BRCA1, MUC16, AKT1, CDH1
39bleomycin44 1111.8CTNNB1, BRCA1, BRCA2
40carboplatin44 50 1112.7AKT1, MUC16, BRCA1
41steroid4410.7PIK3CA, BRCA2, BRCA1, MUC16, CTNNB1
42histamine44 28 2412.7PIK3CA, AKT1, CDH1, CTNNB1
43rapamycin4410.7CTNNB1, CDH1, AKT1, PIK3CA
44cyclopamine44 6111.6CDH1, CTNNB1
45dexamethasone44 50 28 1113.6CTNNB1, CDH1, AKT1, MUC16, PIK3CA
46pd 98,0594410.6PIK3CA, AKT1, CDH1, CTNNB1
47ly2940024410.5CTNNB1, CDH1, AKT1, PIK3CA
48p0034410.5CDH1, BRCA1, BRCA2
49wortmannin4410.4PIK3CA, AKT1, CDH1, CTNNB1
50glycogen44 2411.2CTNNB1, CDH1, AKT1, PIK3CA

GO Terms for genes affiliated with Ovarian Cancer

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Cellular components related to Ovarian Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1BRCA1-BARD1 complexGO:03143610.5BARD1, BRCA1
2cytoplasmGO:00573710.5BRCA2, BRCA1, AKT1, FILIP1L, DPH1, BARD1
3BRCA1-A complexGO:07053110.5BRCA1, BARD1
4catenin complexGO:01634210.4CDH1, CTNNB1
5nucleusGO:00563410.2SPIN1, BRCA2, BRCA1, EEF1A2, AKT1, FILIP1L

Biological processes related to Ovarian Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:00697810.5BRCA1, BRCA2
2cellular response to indole-3-methanolGO:07168110.5CTNNB1, CDH1, BRCA1
3regulation of protein localization to cell surfaceGO:200000810.4CTNNB1, CDH1
4protein K6-linked ubiquitinationGO:08502010.2BARD1, BRCA1

Products for genes affiliated with Ovarian Cancer

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Sources for Ovarian Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet