MCID: OVR078
MIFTS: 44

Ovarian Cancer, Somatic malady

Genetic diseases (common), Cancer diseases categories

Summaries for Ovarian Cancer, Somatic

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48OMIM, 34MalaCards
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MalaCards: Ovarian Cancer, Somatic, also known as malignant neoplasm of ovary, is related to ovarian cancer and fallopian tube cancer. An important gene associated with Ovarian Cancer, Somatic is CTNNB1 (catenin (cadherin-associated protein), beta 1, 88kDa), and among its related pathways are Adherens junction and Colorectal Cancer Metastasis. The compounds sodium bisulfite and 17-(allylamino)-17-demethoxygeldanamycin have been mentioned in the context of this disorder. Affiliated tissues include ovary, and related mouse phenotypes are digestive/alimentary and no phenotypic analysis.

Description from OMIM:48 167000

Aliases & Classifications for Ovarian Cancer, Somatic

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48OMIM, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common), Cancer diseases


Aliases & Descriptions:

ovarian cancer, somatic 48
malignant neoplasm of ovary 63
ovarian carcinoma, somatic 48


Related Diseases for Ovarian Cancer, Somatic

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18GeneCards, 19GeneDecks
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Diseases related to Ovarian Cancer, Somatic via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 48)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian cancer30.2BRCA1, ERBB2, CTNNB1, PIK3CA, CDH1
2fallopian tube cancer10.1BRCA1
3goblet cell carcinoid10.1CTNNB1, CDH1
4malignant mixed mullerian tumor10.0ERBB2, CTNNB1
5inflammatory breast carcinoma10.0CDH1, ERBB2
6synovial sarcoma10.0CDH1, CTNNB1
7stomach cancer10.0ERBB2, CDH1
8male breast cancer10.0BRCA1, ERBB2
9adenoid cystic carcinoma10.0CDH1, ERBB2
10breast cancer10.0BRCA1, AKT1
11li-fraumeni syndrome10.0BRCA1, ERBB2
12bladder carcinoma in situ10.0ERBB2, CDH1
13papillary thyroid carcinoma10.0CDH1, CTNNB1
14hepatocellular carcinoma, somatic10.0PIK3CA, CTNNB1
15autosomal dominant disease10.0BRCA1, AKT1
16tubular adenocarcinoma10.0CDH1, ERBB2, CTNNB1
17endometrial carcinoma10.0CTNNB1, CDH1, ERBB2
18bladder carcinoma10.0ERBB2, CDH1
19familial adenomatous polyposis10.0CTNNB1, CDH1, BRCA1
20gastric cancer, somatic10.0PIK3CA, ERBB2
21breast cancer, invasive ductal10.0BRCA1, CDH1, ERBB2
22ductal carcinoma in situ10.0CDH1, ERBB2, BRCA1
23cowden disease10.0BRCA1, PIK3CA
24thyroid cancer, anaplastic10.0CTNNB1, CDH1, PIK3CA
25papillary carcinoma10.0CDH1, ERBB2
26colorectal cancer, somatic10.0AKT1, CTNNB1, PIK3CA
27cholangiocarcinoma10.0PIK3CA, ERBB2, CDH1
28tuberous sclerosis10.0AKT1, PIK3CA
29squamous cell carcinoma of the head and neck10.0ERBB2, PIK3CA, CDH1
30adenoma10.0CTNNB1, BRCA1, CDH1
31prostate cancer10.0CTNNB1, CDH1, ERBB2, AKT1
32kidney cancer9.9CDH1, PIK3CA, AKT1
33gastric adenocarcinoma9.9CTNNB1, PIK3CA, CDH1, ERBB2
34lung adenocarcinoma9.9CDH1, CTNNB1, ERBB2, PIK3CA
35hypertrophy of breast9.9AKT1, PIK3CA, BRCA1
36astrocytoma9.9BRCA1, AKT1, PIK3CA
37colorectal cancer9.9CDH1, PIK3CA, CTNNB1, ERBB2
38colon cancer9.9CTNNB1, PIK3CA, CDH1, AKT1
39glioblastoma multiforme9.9AKT1, PIK3CA, ERBB2
40hepatocellular carcinoma9.9AKT1, PIK3CA, CTNNB1, CDH1
41medulloblastoma9.9PIK3CA, AKT1, CTNNB1, ERBB2
42melanoma9.9PIK3CA, CDH1, CTNNB1, AKT1
43lung cancer9.9ERBB2, CDH1, AKT1, PIK3CA
44retinoblastoma9.9ERBB2, BRCA1, PIK3CA, AKT1
45non-small cell lung carcinoma9.9AKT1, ERBB2, CTNNB1, PIK3CA, CDH1
46tongue squamous cell carcinoma9.9AKT1, ERBB2, CTNNB1, CDH1, PIK3CA
47pancreatic cancer9.8ERBB2, CDH1, CTNNB1, BRCA1, AKT1, PIK3CA
48adenocarcinoma9.8ERBB2, CDH1, PIK3CA, BRCA1, AKT1, CTNNB1

Graphical network of the top 20 diseases related to Ovarian Cancer, Somatic:



Diseases related to ovarian cancer, somatic

Symptoms for Ovarian Cancer, Somatic

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48OMIM
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Symptoms by clinical synopsis from OMIM:

167000

Clinical features from OMIM:

167000

Drugs & Therapeutics for Ovarian Cancer, Somatic

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Ovarian Cancer, Somatic

Drug clinical trials:

Search ClinicalTrials for Ovarian Cancer, Somatic

Search NIH Clinical Center for Ovarian Cancer, Somatic

Search CenterWatch for Ovarian Cancer, Somatic

Genetic Tests for Ovarian Cancer, Somatic

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Anatomical Context for Ovarian Cancer, Somatic

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34MalaCards
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MalaCards organs/tissues related to Ovarian Cancer, Somatic:

34
Ovary

Animal Models for Ovarian Cancer, Somatic or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Ovarian Cancer, Somatic:

38 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7CTNNB1, BRCA1, ERBB2, CDH1
2MP:00030128.5PIK3CA, OPCML, CDH1, CTNNB1
3MP:00053888.5CTNNB1, ERBB2, AKT1, BRCA1
4MP:00053908.4AKT1, ERBB2, CTNNB1, BRCA1
5MP:00028738.2BRCA1, AKT1, CDH1, CTNNB1, ERBB2
6MP:00053697.9ERBB2, AKT1, PIK3CA, BRCA1, CTNNB1
7MP:00053867.8PIK3CA, BRCA1, AKT1, ERBB2, CTNNB1
8MP:00053877.6CDH1, CTNNB1, AKT1, BRCA1, PIK3CA
9MP:00020067.5CTNNB1, PIK3CA, CDH1, ERBB2, AKT1, BRCA1
10MP:00053797.5PIK3CA, CDH1, CTNNB1, AKT1, BRCA1, ERBB2
11MP:00107717.5PIK3CA, BRCA1, CDH1, ERBB2, AKT1, CTNNB1
12MP:00053807.5CTNNB1, CDH1, ERBB2, BRCA1, PIK3CA, AKT1
13MP:00053897.5PIK3CA, CTNNB1, BRCA1, AKT1, CDH1, ERBB2
14MP:00053857.5PIK3CA, BRCA1, AKT1, ERBB2, CDH1, CTNNB1
15MP:00053847.5ERBB2, CTNNB1, AKT1, BRCA1, PIK3CA, CDH1
16MP:00053787.4CTNNB1, CDH1, AKT1, BRCA1, PIK3CA, ERBB2
17MP:00053767.4ERBB2, PIK3CA, BRCA1, CDH1, AKT1, CTNNB1
18MP:00107687.4ERBB2, CTNNB1, PIK3CA, BRCA1, AKT1, CDH1
19MP:00036317.3AKT1, BRCA1, PIK3CA, ERBB2, CTNNB1

Publications for Ovarian Cancer, Somatic

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Variations for Ovarian Cancer, Somatic

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Sources:
65UniProtKB/Swiss-Prot, 1 National Center for Biotechnology Information (Clinvar), 8dbSNP
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UniProtKB/Swiss-Prot genetic disease variations for Ovarian Cancer, Somatic:

65 (show all 12)
id Symbol AA change Variation ID SNP ID
1BRCA1p.Cys61GlyVAR_007757rs28897672
2BRCA1p.Cys61GlyVAR_007757rs28897672
3BRCA1p.Cys1697ArgVAR_020702
4BRCA1p.Cys1697ArgVAR_020702
5BRCA1p.Arg1699TrpVAR_020703
6BRCA1p.Arg1699TrpVAR_020703
7CTNNB1p.Ser37CysVAR_017625
8CTNNB1p.Ser37CysVAR_017625
9CTNNB1p.Thr41IleVAR_017630
10CTNNB1p.Thr41IleVAR_017630
11OPCMLp.Pro95ArgVAR_055421
12OPCMLp.Pro95ArgVAR_055421

Clinvar genetic disease variations for Ovarian Cancer, Somatic:

1
id Gene Name Type Significance SNP ID Assembly Location
1CDH1NM_004360.3(CDH1): c.2512A> G (p.Ser838Gly)single nucleotide variantLikely benign, Pathogenic, Uncertain significancers121964872GRCh37Chr 16, 68867265: 68867265
2KRASNM_033360.3(KRAS): c.34G> A (p.Gly12Ser)single nucleotide variantPathogenic, drug responsers121913530GRCh37Chr 12, 25398285: 25398285
3PALB2NM_024675.3(PALB2): c.1050_1053delAACA (p.Thr351Argfs)deletionPathogenicrs515726060GRCh38Chr 16, 23635493: 23635496
4ERBB2NM_001005862.2(ERBB2): c.2480A> G (p.Asn827Ser)single nucleotide variantPathogenicrs28933370GRCh37Chr 17, 37881378: 37881378
5AKT1NM_001014431.1(AKT1): c.49G> A (p.Glu17Lys)single nucleotide variantPathogenicrs121434592GRCh37Chr 14, 105246551: 105246551
6CTNNB1NM_001904.3(CTNNB1): c.110C> G (p.Ser37Cys)single nucleotide variantLikely pathogenic, Pathogenicrs121913403GRCh37Chr 3, 41266113: 41266113
7PARK2PARK2, DELdeletionPathogenic
8OPCMLNM_001012393.1(OPCML): c.263C> G (p.Pro88Arg)single nucleotide variantPathogenicrs137852691GRCh37Chr 11, 132527098: 132527098
9RRAS2NM_001177314.1(RRAS2): c.110A> T (p.Gln37Leu)single nucleotide variantPathogenicrs113954997GRCh37Chr 11, 14316390: 14316390

Expression for genes affiliated with Ovarian Cancer, Somatic

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ovarian Cancer, Somatic

Search GEO for disease gene expression data for Ovarian Cancer, Somatic.

Pathways for genes affiliated with Ovarian Cancer, Somatic

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Sources:
51PathCards, 31KEGG, 54QIAGEN, 39NCBI BioSystems Database, 56Reactome, 61Thomson Reuters, 58SinoBiological, 52PharmGKB, 62Tocris Bioscience
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Pathways related to Ovarian Cancer, Somatic according to GeneCards/GeneDecks:

(show top 50)    (show all 115)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.2CDH1, ERBB2, CTNNB1
29.1CDH1, AKT1, CTNNB1
39.1CDH1, CTNNB1, AKT1
49.0AKT1, PIK3CA
5
Show member pathways
DNA damage response (only ATM dependent)39
Wnt Signaling Pathway and Pluripotency39
9.0CTNNB1, AKT1, ERBB2
69.0BRCA1, CTNNB1, AKT1
79.0CTNNB1, AKT1, BRCA1
8
Show member pathways
RAC1 signaling pathway39
8.9PIK3CA, CDH1, CTNNB1
9
Show member pathways
8.9CDH1, PIK3CA, CTNNB1
108.9CTNNB1, CDH1, PIK3CA
118.9CTNNB1, CDH1, PIK3CA
128.7PIK3CA, CTNNB1, AKT1
13
Show member pathways
Development A1 receptor signaling61
G protein signaling G Protein alpha q signaling cascades61
8.7PIK3CA, AKT1, CTNNB1
148.7AKT1, CTNNB1, PIK3CA
15
Show member pathways
Development A2B receptor action via G protein alpha s61
8.7AKT1, CTNNB1, PIK3CA
16
Show member pathways
VEGFR1 specific signals39
8.7PIK3CA, AKT1, CTNNB1
17
Show member pathways
Cytoskeleton remodeling Fibronectin binding integrins in cell motility61
Cytoskeleton remodeling Integrin outside in signaling61
Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases61
Cell adhesion Tight junctions61
Development MAG dependent inhibition of neurite outgrowth61
8.7PIK3CA, AKT1, CTNNB1
188.6CDH1, AKT1, PIK3CA
198.6PIK3CA, AKT1, CDH1
20
Show member pathways
8.5AKT1, ERBB2, CDH1, CTNNB1
218.5CTNNB1, ERBB2, AKT1, CDH1
22
Show member pathways
8.5CTNNB1, AKT1, ERBB2, CDH1
238.5AKT1, CDH1, BRCA1, CTNNB1
24
Show member pathways
Development Ligand independent activation of ESR1 and ESR261
8.5PIK3CA, ERBB2, AKT1
25
Show member pathways
Development EGFR signaling via PIP361
Development PDGF signaling via MAPK cascades61
Apoptosis and survival Anti apoptotic action of membrane bound ESR161
Signaling of Hepatocyte Growth Factor Receptor39
Development EGFR signaling via small GTPases61
Development Neurotrophin family signaling61
Apoptosis and survival NGF signaling pathway61
Apoptosis and survival Role of CDK5 in neuronal death and survival61
8.5PIK3CA, AKT1, ERBB2
26
Show member pathways
ErbB receptor signaling network39
ErbB signaling pathway39
8.5ERBB2, AKT1, PIK3CA
278.5AKT1, PIK3CA, ERBB2
28
Show member pathways
8.5ERBB2, AKT1, PIK3CA
29
Show member pathways
8.5PIK3CA, AKT1, ERBB2
30
Show member pathways
Prolactin Signaling Pathway39
Development Prolactin receptor signaling61
Leptin signaling pathway39
8.5PIK3CA, AKT1, ERBB2
31
Show member pathways
8.5PIK3CA, ERBB2, AKT1
32
Show member pathways
Prostate Cancer39
Integrated Cancer pathway39
Steroid Biosynthesis39
8.5BRCA1, AKT1, PIK3CA
33
Show member pathways
IFN-gamma pathway39
8.5PIK3CA, BRCA1, AKT1
34
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades61
8.5PIK3CA, BRCA1, AKT1
35
Show member pathways
8.4AKT1, CDH1, BRCA1, ERBB2
368.2PIK3CA, CTNNB1, AKT1, CDH1
378.2CDH1, CTNNB1, AKT1, PIK3CA
38
Show member pathways
8.2PIK3CA, AKT1, CDH1, CTNNB1
39
Show member pathways
Integrin-mediated cell adhesion39
Focal Adhesion39
8.1AKT1, PIK3CA, ERBB2, CTNNB1
408.1CTNNB1, ERBB2, PIK3CA, AKT1
41
Show member pathways
8.1CTNNB1, ERBB2, PIK3CA, AKT1
42
Show member pathways
Translation Non genomic rapid action of Androgen Receptor61
8.1AKT1, ERBB2, CTNNB1, PIK3CA
438.1AKT1, CDH1, PIK3CA, ERBB2
44
Show member pathways
8.0CDH1, CTNNB1, AKT1, BRCA1, ERBB2
457.7CDH1, AKT1, PIK3CA, CTNNB1, ERBB2
46
Show member pathways
Signal transduction PTEN pathway61
7.7ERBB2, PIK3CA, AKT1, CTNNB1, CDH1
47
Show member pathways
Development ERBB family signaling61
Development GDNF family signaling61
7.7AKT1, ERBB2, PIK3CA, CTNNB1, CDH1
487.6PIK3CA, BRCA1, AKT1, CTNNB1, ERBB2
49
Show member pathways
7.6AKT1, ERBB2, CDH1, PIK3CA, BRCA1
50
Show member pathways
Signaling Pathways in Glioblastoma39
7.2CTNNB1, ERBB2, AKT1, CDH1, BRCA1, PIK3CA

Compounds for genes affiliated with Ovarian Cancer, Somatic

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Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 52PharmGKB, 25HMDB, 12DrugBank, 3BitterDB
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Compounds related to Ovarian Cancer, Somatic according to GeneCards/GeneDecks:

(show top 50)    (show all 110)
idCompoundScoreTop Affiliating Genes
1sodium bisulfite469.5CTNNB1, BRCA1, CDH1
217-(allylamino)-17-demethoxygeldanamycin469.2AKT1, ERBB2, CDH1
3crcs469.1PIK3CA, CDH1, CTNNB1
4p002469.0CDH1, ERBB2, BRCA1, CTNNB1
5indole-3-carbinol469.0AKT1, CDH1, CTNNB1, BRCA1
6celecoxib46 62 30 52 25 1214.0CTNNB1, CDH1, ERBB2, AKT1
7nocodazole46 129.9BRCA1, AKT1, CDH1, CTNNB1
8mg 13246 629.9AKT1, BRCA1, CDH1, CTNNB1
9herbimycin a46 629.9CDH1, CTNNB1, AKT1, ERBB2
10leptomycin b46 629.9BRCA1, CDH1, CTNNB1
11curcumin468.9ERBB2, CDH1, AKT1, CTNNB1
12everolimus46 52 1210.9ERBB2, PIK3CA, AKT1
134-hydroxytamoxifen468.8ERBB2, AKT1, BRCA1, CTNNB1
14erlotinib46 52 1210.8ERBB2, PIK3CA, CDH1
15guanine46 25 1210.7ERBB2, AKT1, CTNNB1, BRCA1
16egcg468.7CTNNB1, CDH1, ERBB2, PIK3CA
17n acetylcysteine468.7CDH1, CTNNB1, ERBB2, AKT1
18resveratrol46 62 25 1211.6BRCA1, PIK3CA, ERBB2, CTNNB1
19docetaxel46 52 62 1211.6CDH1, ERBB2, PIK3CA, BRCA1
20ag 1478468.5ERBB2, PIK3CA, CTNNB1, AKT1
21adriamycin468.5AKT1, ERBB2, CDH1, CTNNB1, BRCA1
22matrigel468.4CTNNB1, PIK3CA, AKT1, CDH1
23paraffin468.4BRCA1, AKT1, CTNNB1, CDH1, ERBB2
245fluorouracil468.3BRCA1, PIK3CA, CDH1, CTNNB1, ERBB2
25pd 98,059468.2CDH1, CTNNB1, PIK3CA, AKT1
26phosphotyrosine468.2ERBB2, CTNNB1, CDH1, BRCA1, PIK3CA
27gefitinib46 52 1210.2ERBB2, PIK3CA, AKT1, CTNNB1, CDH1
28histamine46 30 2510.1CDH1, AKT1, PIK3CA, CTNNB1
29progesterone46 30 62 25 1212.1ERBB2, CDH1, CTNNB1, BRCA1, PIK3CA
30rapamycin468.1CTNNB1, PIK3CA, AKT1, ERBB2, CDH1
31ly294002468.1CTNNB1, PIK3CA, AKT1, ERBB2, CDH1
32wortmannin468.1CTNNB1, PIK3CA, AKT1, CDH1, ERBB2
33alanine468.0CDH1, ERBB2, AKT1, CTNNB1, BRCA1
34etoposide46 52 62 1211.0PIK3CA, BRCA1, AKT1, CDH1, ERBB2
35dexamethasone46 52 30 1211.0CTNNB1, CDH1, ERBB2, PIK3CA, AKT1
36h2o2467.9ERBB2, PIK3CA, BRCA1, CTNNB1, AKT1
37arginine467.9PIK3CA, AKT1, CTNNB1, ERBB2, CDH1
38glutamate467.8CDH1, AKT1, ERBB2, CTNNB1, PIK3CA
39agar467.7PIK3CA, BRCA1, AKT1, ERBB2, CTNNB1, CDH1
40tamoxifen46 52 30 1210.7CTNNB1, CDH1, ERBB2, PIK3CA, BRCA1, AKT1
41paclitaxel46 52 129.6ERBB2, PIK3CA, CTNNB1, BRCA1, CDH1, AKT1
42doxorubicin46 52 129.6PIK3CA, BRCA1, AKT1, ERBB2, CTNNB1, CDH1
43genistein46 30 62 3 25 1212.6CDH1, BRCA1, PIK3CA, AKT1, ERBB2, CTNNB1
44cisplatin46 52 62 1210.6PIK3CA, CDH1, CTNNB1, ERBB2, AKT1, BRCA1
45testosterone46 62 25 1210.6BRCA1, PIK3CA, CTNNB1, CDH1, ERBB2, AKT1
46vegf467.6PIK3CA, CTNNB1, CDH1, ERBB2, AKT1, BRCA1
47phosphatidylinositol467.6PIK3CA, BRCA1, ERBB2, CDH1, CTNNB1, AKT1
48estrogen467.6AKT1, PIK3CA, BRCA1, ERBB2, CDH1, CTNNB1
49serine467.5BRCA1, CDH1, ERBB2, AKT1, PIK3CA, CTNNB1
50tyrosine467.4BRCA1, CTNNB1, CDH1, AKT1, ERBB2, PIK3CA

GO Terms for genes affiliated with Ovarian Cancer, Somatic

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17Gene Ontology
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Cellular components related to Ovarian Cancer, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1catenin complexGO:0163429.8CTNNB1, CDH1
2cell-cell adherens junctionGO:0059139.8CTNNB1, CDH1
3cytoplasmic side of plasma membraneGO:0098989.7CTNNB1, CDH1
4apical part of cellGO:0451779.7CTNNB1, CDH1
5lateral plasma membraneGO:0163289.6CDH1, CTNNB1
6basolateral plasma membraneGO:0163239.3ERBB2, CDH1, CTNNB1
7perinuclear region of cytoplasmGO:0484718.9CTNNB1, CDH1, ERBB2
8plasma membraneGO:0058866.9CTNNB1, PIK3CA, BRCA1, AKT1, ERBB2, OPCML

Biological processes related to Ovarian Cancer, Somatic according to GeneCards/GeneDecks:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1regulation of protein localization to cell surfaceGO:200000810.0CTNNB1, CDH1
2cellular component disassembly involved in execution phase of apoptosisGO:0069219.8CDH1, CTNNB1
3regulation of angiogenesisGO:0457659.8CTNNB1, ERBB2
4androgen receptor signaling pathwayGO:0305219.7CTNNB1, BRCA1
5cellular response to indole-3-methanolGO:0716819.5CTNNB1, CDH1, BRCA1
6cellular response to mechanical stimulusGO:0712609.5CTNNB1, AKT1
7protein kinase B signalingGO:0434919.2AKT1, PIK3CA
8positive regulation of peptidyl-serine phosphorylationGO:0331389.1AKT1, PIK3CA
9positive regulation of transcription, DNA-templatedGO:0458939.1BRCA1, CDH1, CTNNB1
10positive regulation of cell growthGO:0303079.0ERBB2, AKT1
11T cell costimulationGO:0312959.0AKT1, PIK3CA
12apoptotic processGO:0069158.8BRCA1, AKT1, CDH1, CTNNB1
13phosphatidylinositol-mediated signalingGO:0480158.8PIK3CA, AKT1, ERBB2
14fibroblast growth factor receptor signaling pathwayGO:0085438.8PIK3CA, AKT1, ERBB2
15Fc-epsilon receptor signaling pathwayGO:0380958.8ERBB2, AKT1, PIK3CA
16epidermal growth factor receptor signaling pathwayGO:0071738.8PIK3CA, AKT1, ERBB2
17neurotrophin TRK receptor signaling pathwayGO:0480118.7PIK3CA, AKT1, ERBB2
18innate immune responseGO:0450878.4CTNNB1, ERBB2, AKT1, PIK3CA

Molecular functions related to Ovarian Cancer, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1androgen receptor bindingGO:0506819.5BRCA1, CTNNB1
2protein phosphatase bindingGO:0199039.2CTNNB1, CDH1, ERBB2
3enzyme bindingGO:0198999.0CTNNB1, AKT1, BRCA1
4kinase activityGO:0163018.7PIK3CA, AKT1
5protein bindingGO:0055157.2CTNNB1, CDH1, ERBB2, AKT1, BRCA1, PIK3CA

Products for genes affiliated with Ovarian Cancer, Somatic

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  • Antibodies
  • Proteins
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Sources for Ovarian Cancer, Somatic

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet