MCID: OVR034
MIFTS: 45

Ovarian Clear Cell Adenocarcinoma malady

Summaries for Ovarian Clear Cell Adenocarcinoma

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MalaCards: Ovarian Clear Cell Adenocarcinoma is related to clear cell adenocarcinoma and adenocarcinoma. An important gene associated with Ovarian Clear Cell Adenocarcinoma is PTHLH (parathyroid hormone-like hormone), and among its related pathways are Remodeling of Adherens Junctions and Immune response IL-2 activation and signaling pathway. The compounds glutamate and crcs have been mentioned in the context of this disorder. Affiliated tissues include ovary and endothelial, and related mouse phenotypes are nervous system and integument.

Aliases & Classifications for Ovarian Clear Cell Adenocarcinoma

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8Disease Ontology, 60UMLS, 39NCIt
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Aliases & Descriptions:

ovarian clear cell adenocarcinoma 8 60


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Disease Ontology8 DOID:5304
NCIt39 C40078

Related Diseases for Ovarian Clear Cell Adenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Ovarian Clear Cell Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1clear cell adenocarcinoma31.7PTHLH, SMAD3, SMAD2, SMAD4
2adenocarcinoma31.7SMAD4, STS, PIK3CA, WT1, HNF1B, STMN1
3endometriosis30.8HNF1B, STS, AHR, ESR2
4ovarian endometriosis10.5
5hypercalcemia10.4
6renal clear cell carcinoma10.2
7ovarian mucinous adenocarcinoma10.2
8endometrial clear cell adenocarcinoma10.2
9mucinous adenocarcinoma10.2
10endometrial adenocarcinoma10.2
11ovary adenocarcinoma10.2
12renal cell carcinoma10.2
13pancreatitis10.0SMAD4
14leiomyosarcoma10.0WT1
15myeloid leukemia10.0WT1
16hepatitis10.0AFP
17pituitary adenoma10.0ESR2
18goiter10.0INHBA
19infertility10.0ESR2
20nephrosis10.0ACTN4
21myeloma10.0MET, PTHLH
22thyroid cancer10.0PIK3CA, MET
23medulloblastoma10.0STMN1, PIK3CA
24prolactinoma10.0ESR2, PTHLH
25cryptorchidism10.0STS, WT1
26leydig cell tumor10.0PTHLH
27osteoarthritis10.0ESR2, PTHLH
28down syndrome10.0AFP, STS
29wilms tumor10.0ACTN4, WT1
30rhabdoid tumor10.0WT1
31diabetes mellitus10.0ESR2, GPX3, HNF1B
32sarcoma10.0WT1, STMN1, MET
33frasier syndrome10.0WT1
34papillary thyroid carcinoma10.0MET, PIK3CA, HNF1B
35islet cell tumor10.0PTHLH, AFP
36thyroid cancer, anaplastic10.0PIK3CA, MET, PTHLH
37primary hyperoxaluria10.0WT1, SMAD2
38cervical cancer10.0PIK3CA, SMAD2, SMAD4
39hemihypertrophy10.0WT1
40malignant mesothelioma10.0MET, WT1
41cholestasis10.0HNF1B, SMAD2
42chondrosarcoma10.0MET, PTHLH
43hepatoblastoma10.0MET, AFP, AHR
44dysgerminoma10.0WT1, AFP, PTHLH
45familial adenomatous polyposis10.0SMAD4, SMAD2, SMAD3
46polycystic ovary syndrome10.0ESR2
47kidney rhabdoid cancer10.0MET, PIK3CA, WT1
48astrocytoma10.0MET, PIK3CA, TUBB3
49nephrotic syndrome10.0ACTN4, WT1
50glioblastoma multiforme10.0SMAD4, MET, PIK3CA, TUBB3

Graphical network of the top 20 diseases related to Ovarian Clear Cell Adenocarcinoma:



Diseases related to ovarian clear cell adenocarcinoma

Clinical Features for Ovarian Clear Cell Adenocarcinoma

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Drugs & Therapeutics for Ovarian Clear Cell Adenocarcinoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Ovarian Clear Cell Adenocarcinoma

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Anatomical Context for Ovarian Clear Cell Adenocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Ovarian Clear Cell Adenocarcinoma:

32
Ovary, Endothelial

Animal Models for Ovarian Clear Cell Adenocarcinoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Ovarian Clear Cell Adenocarcinoma:

36 (show all 22)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000363110.2TUBB3, GPX3, ESR2
2MP:001077110.0PIK3CA, AHR, SMAD3, SMAD2, SMAD4
3MP:00053919.9SMAD2, INHBA
4MP:00053899.8WT1, PIK3CA, NEU4, AFP, SMAD3, SMAD2
5MP:00053699.7HNF1B, WT1, STMN1, MET, AHR, INHBA
6MP:00030129.7PIK3CA, MET, AHR, ESR2, SMAD2, WT1
7MP:00020069.7PIK3CA, MET, AFP, AHR, ESR2, SMAD3
8MP:00053709.7HNF1B, WT1, MET, AHR, ESR2, SMAD3
9MP:00053889.6TUBB3, MET, AHR, PTHLH, ESR2, SMAD2
10MP:00053819.6MET, AHR, INHBA, PTHLH, ESR2, SMAD3
11MP:00053799.6HNF1B, WT1, PIK3CA, AFP, AHR, INHBA
12MP:00053809.6HNF1B, WT1, PIK3CA, MET, INHBA, SMAD3
13MP:00053769.4NEU4, STMN1, PIK3CA, HNF1B, AFP, INHBA
14MP:00028739.4WT1, STMN1, MET, MAP4, INHBA, ESR2
15MP:00053879.3HNF1B, WT1, PIK3CA, MET, AHR, ACTN4
16MP:00053849.3TUBB3, WT1, PIK3CA, MET, NEU4, ACTN4
17MP:00053979.3WT1, AHR, INHBA, GPX3, PTHLH, ESR2
18MP:00053859.2WT1, PIK3CA, STMN1, MET, AHR, GPX3
19MP:00053869.2PIK3CA, MET, NEU4, AFP, ANXA4, INHBA
20MP:00053679.2SMAD4, HNF1B, WT1, MET, ANXA4, AHR
21MP:00053788.9AHR, NEU4, MET, PIK3CA, WT1, HNF1B
22MP:00107688.7AFP, NEU4, MET, PIK3CA, WT1, TUBB3

Publications for Ovarian Clear Cell Adenocarcinoma

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50PubMed
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Articles related to Ovarian Clear Cell Adenocarcinoma:

(show top 50)    (show all 92)
idTitleAuthorsYear
1
Integrative analysis of copy number alteration and gene expression profiling in ovarian clear cell adenocarcinoma. (23726144)
2013
2
ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis. (23762304)
2013
3
Annexin A4 is involved in proliferation, chemo-resistance and migration and invasion in ovarian clear cell adenocarcinoma cells. (24244679)
2013
4
Establishment and characterization of a novel ovarian clear cell adenocarcinoma cell line, TU-OC-1, with a mutation in the PIK3CA gene. (23430509)
2013
5
Secretome-based identification of TFPI2, a novel serum biomarker for detection of ovarian clear cell adenocarcinoma. (23805888)
2013
6
Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis. (23469222)
2013
7
A recurrence-predicting prognostic factor for patients with ovarian clear-cell adenocarcinoma at reproductive age. (24306200)
2013
8
Paraneoplastic hypercalcemia in clear cell ovarian adenocarcinoma. (23056149)
2012
9
PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma. (22120431)
2012
10
Two cases of ovarian clear cell adenocarcinoma producing estradiol. (22360511)
2012
11
Mixed angiosarcoma, clear cell adenocarcinoma and mature teratoma elements in an ovarian tumor: a case report and literature review. (22827762)
2012
12
Re-expression of estrogen receptor I^ inhibits the proliferation and migration of ovarian clear cell adenocarcinoma cells. (21874257)
2011
13
Immunohistochemical evidence for the over-expression of Glutathione peroxidase 3 in clear cell type ovarian adenocarcinoma. (20730571)
2011
14
Biological significance of plasminogen activator inhibitor-1 expression in ovarian clear cell adenocarcinoma. (22335020)
2011
15
Validation of the histologic grading for ovarian clear cell adenocarcinoma: a retrospective multi-institutional study by the Japan Clear Cell Carcinoma Study Group. (21293288)
2011
16
Clear cell adenocarcinoma with a component of poorly differentiated histology: a poor prognostic subgroup of ovarian clear cell adenocarcinoma. (21804390)
2011
17
Gene amplification and protein overexpression of MET are common events in ovarian clear-cell adenocarcinoma: their roles in tumor progression and prognostication of the patient. (21478826)
2011
18
CRABP1-reduced expression is associated with poorer prognosis in serous and clear cell ovarian adenocarcinoma. (20571827)
2011
19
Differential expression of hypoxia-inducible protein 2 among different histological types of epithelial ovarian cancer and in clear cell adenocarcinomas. (20134266)
2010
20
Expression of podoplanin in epithelial ovarian carcinomas and its potential as a marker for clear cell adenocarcinoma. (20736762)
2010
21
Prognostic and predictive values of E-cadherin for patients of ovarian clear cell adenocarcinoma. (21119364)
2010
22
Promoter methylation of sFRP5 in patients with ovarian clear cell adenocarcinoma. (20486992)
2010
23
HOXA10 is overexpressed in human ovarian clear cell adenocarcinoma and correlates with poor survival. (20009888)
2009
24
Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma. (19121088)
2009
25
Overexpression of class III beta-tubulin predicts good response to taxane-based chemotherapy in ovarian clear cell adenocarcinoma. (19228748)
2009
26
A synthetic retinoid, TAC-101 (4-[3,5-bis (trimethylsilyl) benzamido] benzoic acid), plus cisplatin: potential new therapy for ovarian clear cell adenocarcinoma. (18048092)
2008
27
Obstructive uropathy as a major presentation of ovarian clear cell adenocarcinoma. (18400599)
2008
28
Potential benefit of Sunitinib in recurrent and refractory ovarian clear cell adenocarcinoma. (18081793)
2008
29
Specific expression of hepatocyte nuclear factor-1beta in the ovarian clear cell adenocarcinoma and its application to cytological diagnosis. (17270029)
2007
30
Ovarian clear cell adenocarcinoma producing alpha-fetoprotein: case report. (17624099)
2007
31
Sperm protein 17 influences the tissue-specific malignancy of clear cell adenocarcinoma in human epithelial ovarian cancer. (17309563)
2007
32
Ovarian clear cell adenocarcinoma: a continuing enigma. (17018684)
2007
33
Loss of integrin alpha3 expression associated with acquisition of invasive potential by ovarian clear cell adenocarcinoma cells. (17022147)
2005
34
Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses. (16203778)
2005
35
Antiproliferative effects of interferon-alphaCon1 on ovarian clear cell adenocarcinoma in vitro and in vivo. (15534119)
2004
36
Overexpression of HER-2/neu is not a risk factor in ovarian clear cell adenocarcinoma. (15350366)
2004
37
Selective inhibition of the epidermal growth factor receptor by ZD1839 decreases the growth and invasion of ovarian clear cell adenocarcinoma cells. (12114452)
2002
38
Complete response to radiation therapy in a patient with chemotherapy-resistant ovarian clear cell adenocarcinoma. (12439556)
2002
39
Steroid sulfatase expression in ovarian clear cell adenocarcinoma: immunohistochemical study. (11520136)
2001
40
Hypercalcemia due to parathyroid hormone-related protein produced by primary ovarian clear cell adenocarcinoma: case report. (10637074)
2000
41
A pilot study of CPT-11 and cisplatin for ovarian clear cell adenocarcinoma. (10563197)
1999
42
Survival probability in ovarian clear cell adenocarcinoma. (10385560)
1999
43
Establishment and characterization of human ovarian clear cell adenocarcinoma cell line (SMOV-2), and its cytotoxity by anticancer agents. (10695021)
1999
44
Remarkable suppressive effect of consecutive low-dose cisplatin therapy on advanced ovarian clear cell adenocarcinoma. (10425299)
1999
45
Appearance of primary endometrial and ovarian clear cell adenocarcinoma 17 months postpartum. A case report. (9622703)
1998
46
Establishment and characterization of two human ovarian clear cell adenocarcinoma lines from metastatic lesions with different properties. (7535723)
1995
47
Histologic correlates of progression-free interval and survival in ovarian clear cell adenocarcinoma. (8406197)
1993
48
Ovarian clear cell adenocarcinoma. (2920955)
1989
49
Establishment of HUOCA-II, a human ovarian clear cell adenocarcinoma cell line, and its angiogenic activity. (2435943)
1987
50
Clear-cell adenocarcinoma in an endometrioid ovarian cyst. (4286320)
1966

Genetic Variations for Ovarian Clear Cell Adenocarcinoma

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Expression for genes affiliated with Ovarian Clear Cell Adenocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ovarian Clear Cell Adenocarcinoma

Search GEO for disease gene expression data for Ovarian Clear Cell Adenocarcinoma.

Pathways for genes affiliated with Ovarian Clear Cell Adenocarcinoma

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Sources:
51QIAGEN, 12EMD Millipore, 29KEGG, 37NCBI BioSystems Database, 52R&D Systems, 53Reactome, 4Cell Signaling Technology
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Pathways related to Ovarian Clear Cell Adenocarcinoma according to GeneCards/GeneDecks:

(show all 29)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2TUBB3, MET, ACTN4
2
Immune response IL-2 activation and signaling pathway
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10.1SMAD4, SMAD3, PIK3CA
310.1SMAD2, SMAD3, PIK3CA
4
Hide members
10.1SMAD2, SMAD3, PIK3CA
510.0SMAD4, SMAD2, SMAD3
6
Hide members
10.0SMAD4, SMAD2, SMAD3
710.0SMAD4, SMAD2, SMAD3
8
Hide members
10.0SMAD4, SMAD2, SMAD3
9
Development TGF-beta receptor signaling
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10.0SMAD4, SMAD2, SMAD3
1010.0SMAD4, SMAD2, SMAD3
11
Cytokine production by Th17 cells in CF (Mouse model)
10.0SMAD3, SMAD2, SMAD4
1210.0SMAD3, SMAD2, SMAD4
13
Hide members
10.0SMAD3, SMAD2, SMAD4
1410.0SMAD3, SMAD2, SMAD4
1510.0SMAD4, SMAD2, INHBA
1610.0SMAD4, SMAD3, INHBA
1710.0PIK3CA, MET, SMAD3, SMAD2
18
Hide members
9.9PIK3CA, SMAD3, SMAD2, SMAD4
19
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9.9PIK3CA, SMAD3, SMAD2, SMAD4
20
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9.9PIK3CA, SMAD3, SMAD2, SMAD4
219.9SMAD4, SMAD2, SMAD3, PIK3CA
229.9ESR2, SMAD3, SMAD2, SMAD4
239.9AFP, SMAD3, SMAD2, SMAD4
249.9SMAD4, SMAD2, SMAD3, INHBA
25
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9.9INHBA, SMAD3, SMAD2, SMAD4
269.9INHBA, SMAD3, SMAD2, SMAD4
279.8MET, ACTN4, SMAD3, SMAD2, SMAD4
28
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9.7AHR, INHBA, SMAD3, SMAD2, SMAD4
299.5SMAD4, SMAD2, ESR2, INHBA, STMN1, PIK3CA

Compounds for genes affiliated with Ovarian Clear Cell Adenocarcinoma

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44Novoseek, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR, 49PharmGKB, 2BitterDB
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Compounds related to Ovarian Clear Cell Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 61)
idCompoundScoreTop Affiliating Genes
1glutamate4410.4MAP4, AHR
2crcs4410.4SMAD4, MET, PIK3CA
3progestin4410.3STS, AHR, PTHLH, ESR2
4bleomycin44 1111.3AFP, PTHLH, SMAD3, SMAD2
5arsenite44 2411.3PIK3CA, STS, AHR
6nocodazole44 1111.2SMAD2, PTHLH, MAP4, STMN1
7agar4410.2SMAD4, PTHLH, AFP, MET, PIK3CA
8leptomycin b44 5911.2AHR, PTHLH, SMAD3, SMAD2, SMAD4
9estrone44 28 11 2413.2STS, AFP, AHR, ESR2
10kaempferol4410.2ESR2, AHR
11ccl444 2811.2PTHLH, AFP, MET
12tgf beta14410.2AFP, PTHLH, SMAD3, SMAD2, SMAD4
13matrigel4410.2SMAD2, SMAD3, PTHLH, MET, PIK3CA
14paclitaxel44 49 1112.2TUBB3, PIK3CA, STMN1, AFP, MAP4
15dmso4410.2TUBB3, PIK3CA, AFP, AHR, ESR2
16dihydrotestosterone44 28 11 2413.1STS, PTHLH, ESR2, SMAD3, SMAD2, SMAD4
17tamoxifen44 49 28 1113.1PIK3CA, STS, AHR, PTHLH, ESR2
18cisplatin44 49 59 1113.1TUBB3, PIK3CA, STMN1, MET, AFP, PTHLH
19actinomycin d4410.1PIK3CA, MET, AFP, AHR, PTHLH, ESR2
20thyroxine44 2411.1PTHLH, GPX3, AHR, AFP
21etoposide44 49 59 1113.1WT1, PIK3CA, AFP, ESR2, SMAD3
22dexamethasone44 49 28 1113.1PIK3CA, AFP, AHR, GPX3, SMAD2
23paraffin4410.1WT1, MET, AFP, PTHLH, ESR2, SMAD4
24pd 98,0594410.1PIK3CA, STMN1, MET, SMAD3, SMAD2, SMAD4
25steroid4410.0WT1, PIK3CA, STS, AFP, AHR, PTHLH
26vitamin d4410.0WT1, MET, AFP, AHR, PTHLH, ESR2
27heparin44 28 11 2413.0PTHLH, GPX3, ANXA4, AFP, MET, PIK3CA
28doxorubicin44 49 1111.9WT1, PIK3CA, STMN1, MET, AFP, MAP4
29estradiol44 11 2411.9STS, AFP, AHR, GPX3, PTHLH, ESR2
30chloramphenicol44 2 1111.9WT1, AFP, ESR2, SMAD4
31cholesterol44 28 11 2412.9HNF1B, PIK3CA, STS, MET, AFP, GPX3
32lysine449.9WT1, ANXA4, PTHLH, SMAD3, SMAD2
33map444 2810.9MAP4, STMN1
34glucose449.8HNF1B, PIK3CA, MET, GPX3, PTHLH, SMAD3
35progesterone44 59 28 11 2413.8WT1, PIK3CA, STS, STMN1, MET, AFP
36thymidine44 2410.8WT1, PIK3CA, STMN1, MET, AFP, PTHLH
37cysteine449.8WT1, STS, MET, ANXA4, AHR, ESR2
38nitric oxide44 11 2411.7TUBB3, WT1, PIK3CA, MET, GPX3, PTHLH
39creatinine449.7WT1, STMN1, AFP, GPX3, PTHLH
40serine449.7STS, PIK3CA, WT1, TUBB3, STMN1, AFP
41lipid449.7PIK3CA, STS, MET, AFP, ANXA4, GPX3
42threonine449.7MET, STMN1, PIK3CA, WT1, AFP, ACTN4
43arginine449.6MET, PIK3CA, WT1, HNF1B, ANXA4, AHR
44vegf449.6WT1, PIK3CA, MET, AFP, AHR, PTHLH
45oligonucleotide449.6HNF1B, WT1, STS, STMN1, MET, AFP
46alanine449.6MET, AFP, MAP4, AHR, GPX3, PTHLH
47retinoic acid44 2410.6PIK3CA, WT1, TUBB3, HNF1B, STS, STMN1
48calcium44 49 11 2412.5TUBB3, PIK3CA, STS, STMN1, MET, AFP
49testosterone44 59 11 2412.5SMAD4, WT1, PIK3CA, STS, MET, AFP
50tyrosine449.3STMN1, STS, PIK3CA, WT1, TUBB3, MET

GO Terms for genes affiliated with Ovarian Clear Cell Adenocarcinoma

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16Gene Ontology
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Cellular components related to Ovarian Clear Cell Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1SMAD protein complexGO:07114110.0SMAD4, SMAD2, SMAD3
2activin responsive factor complexGO:0324449.9SMAD4, SMAD2
3transcription factor complexGO:0056679.7HNF1B, AHR, SMAD3, SMAD2, SMAD4
4cytoplasmGO:0057378.9WT1, AFP, ANXA4, MAP4, AHR, ACTN4

Biological processes related to Ovarian Clear Cell Adenocarcinoma according to GeneCards/GeneDecks:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1paraxial mesoderm morphogenesisGO:04834010.4SMAD2, SMAD3
2regulation of bindingGO:05109810.4SMAD4, SMAD2, SMAD3
3regulation of transforming growth factor beta2 productionGO:03290910.4SMAD4, SMAD3
4SMAD protein complex assemblyGO:00718310.4SMAD3, SMAD2, SMAD4
5endoderm developmentGO:00749210.4PTHLH, SMAD3, SMAD4
6regulation of transforming growth factor beta receptor signaling pathwayGO:01701510.4SMAD4, SMAD2, SMAD3
7positive regulation of epithelial to mesenchymal transitionGO:01071810.3SMAD4, SMAD2, SMAD3
8activin receptor signaling pathwayGO:03292410.3INHBA, SMAD3, SMAD2
9primary miRNA processingGO:03105310.3SMAD2, SMAD3
10developmental growthGO:04858910.3SMAD3, SMAD2, SMAD4
11ureteric bud developmentGO:00165710.3SMAD2, SMAD3, WT1
12positive regulation of cellular component movementGO:05127210.3ACTN4, STMN1
13nodal signaling pathwayGO:03809210.2SMAD3, SMAD2
14negative regulation of cell growthGO:03030810.1SMAD4, SMAD3, ESR2, INHBA, WT1
15pericardium developmentGO:06003910.1SMAD3, SMAD2
16palate developmentGO:06002110.0SMAD4, SMAD2, INHBA
17transcription initiation from RNA polymerase II promoterGO:00636710.0ESR2, SMAD3, SMAD2, SMAD4
18negative regulation of cell proliferationGO:00828510.0WT1, INHBA, PTHLH, SMAD2, SMAD4
19positive regulation of transcription, DNA-dependentGO:0458939.9SMAD4, SMAD2, SMAD3, INHBA, WT1, HNF1B
20embryonic foregut morphogenesisGO:0486179.9SMAD2, SMAD3
21negative regulation of transcription from RNA polymerase II promoterGO:0001229.8SMAD4, SMAD2, SMAD3, ESR2, AHR, WT1
22positive regulation of transcription from RNA polymerase II promoterGO:0459449.8HNF1B, MET, INHBA, SMAD3, SMAD2, SMAD4

Molecular functions related to Ovarian Clear Cell Adenocarcinoma according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activityGO:03061810.4SMAD2, SMAD3
2R-SMAD bindingGO:07041210.3SMAD3, SMAD2, SMAD4
3I-SMAD bindingGO:07041110.3SMAD4, SMAD2
4core promoter proximal region sequence-specific DNA bindingGO:00098710.2SMAD4, SMAD3
5co-SMAD bindingGO:07041010.2SMAD3, SMAD2
6transforming growth factor beta receptor bindingGO:00516010.1SMAD3, SMAD2
7transcription regulatory region DNA bindingGO:04421210.0SMAD4, SMAD3, AHR, WT1, HNF1B
8transcription factor bindingGO:00813410.0AHR, GPX3, SMAD3, SMAD2
9sequence-specific DNA bindingGO:0435659.9HNF1B, WT1, AHR, SMAD3, SMAD4
10protein binding transcription factor activityGO:0009889.9SMAD4, SMAD3
11sequence-specific DNA binding transcription factor activityGO:0037009.7HNF1B, WT1, AHR, ESR2, SMAD3, SMAD2
12protein bindingGO:0055158.9NEU4, MET, PIK3CA, WT1, HNF1B, MAP4

Products for genes affiliated with Ovarian Clear Cell Adenocarcinoma

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Sources for Ovarian Clear Cell Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet