MCID: OVR046
MIFTS: 47

Ovarian Cyst malady

Reproductive diseases, Cancer diseases categories

Summaries for Ovarian Cyst

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Sources:
35MedlinePlus, 66Wikipedia, 34MalaCards
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MedlinePlus:35 A cyst is a fluid-filled sac. in most cases a cyst on the ovary does no harm and goes away by itself. most women have them sometime during their lives. cysts are rarely cancerous in women under 50. cysts sometimes hurt - but not always. often, a woman finds out about a cyst when she has a pelvic exam. if you're in your childbearing years or past menopause, have no symptoms, and have a fluid-filled cyst, you may choose to monitor the cyst. you may need surgery if you have pain, are past menopause or if the cyst does not go away. birth control pills can help prevent new cysts. a health problem that may involve ovarian cysts is polycystic ovary syndrome (pcos). women with pcos can have high levels of male hormones, irregular or no periods and small ovarian cysts. dept. of health and human services office on women's health

MalaCards: Ovarian Cyst, also known as ovarian cysts, is related to neonatal ovarian cyst and malignant ovarian cyst. An important gene associated with Ovarian Cyst is PRSS2 (protease, serine, 2 (trypsin 2)), and among its related pathways are G protein signaling Ras family GTPases in kinase cascades scheme and Cell adhesion ECM remodeling. The compounds barbiturate and amide have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and breast.

Wikipedia:66 An ovarian cyst is any collection of fluid, surrounded by a very thin wall, within an ovary. Any ovarian... more...

Aliases & Classifications for Ovarian Cyst

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9Disease Ontology, 46Novoseek, 35MedlinePlus, 63UMLS, 59SNOMED-CT, 28ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Reproductive diseases


Aliases & Descriptions:

ovarian cyst 9
ovarian cysts 46 35 63


External Ids:

Disease Ontology9 DOID:5119
SNOMED-CT59 198586000
ICD9CM28 620.2

Related Diseases for Ovarian Cyst

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18GeneCards, 19GeneDecks
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Diseases in the Ovarian Cyst family:

Malignant Ovarian Cyst

Diseases related to Ovarian Cyst via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1neonatal ovarian cyst10.6
2malignant ovarian cyst10.5
3ovarian cancer10.4
4peritonitis10.4
5meningocele10.4
6hypothyroidism10.4
7mccune albright syndrome10.3
8ectopic pregnancy10.3
9breast cancer10.3
10leiomyoma10.3
11polyhydramnios10.2
12adenoma10.2
13cervicitis10.2
14endometriosis10.2
15pulmonary embolism10.2
16vaginitis10.2
17endotheliitis10.2
18ovarian hyperstimulation syndrome10.1
19hydronephrosis10.1
20endometritis10.1
21intestinal obstruction10.1
22obesity10.1
23pancreatitis10.1
24precocious puberty10.1
25lipoid adrenal hyperplasia10.1
26periodontitis10.1MMP8
27oral submucous fibrosis10.1MMP1
28periodontal disease10.1MMP1
29periapical granuloma10.0MMP8, MMP13
30aggressive periodontitis10.0MMP8, MMP1
31pulmonary emphysema10.0MMP8, MMP1
32keratoconus10.0MMP1, MMP8
33arthropathy10.0MMP1, MMP13
34laryngeal squamous cell carcinoma10.0MMP1, MMP13
35esophageal cancer10.0MMP1, MMP13
36basal cell carcinoma10.0MMP13, MMP1
37chondrosarcoma10.0MMP1, MMP13
38osteoporosis10.0MMP8, MMP13
39pulmonary fibrosis10.0MMP13, MMP1
40pulmonary disease, chronic obstructive10.0MMP1, MMP8
41premature ovarian failure10.0FOXL2, NOBOX
42squamous cell carcinoma of the head and neck10.0MMP1, MMP13
43cork-handlers' disease10.0PRSS2, MMP8
44gingivitis10.0MMP1, MMP8, MMP13
45abdominal aortic aneurysm10.0MMP1, MMP8, MMP13
46keloids10.0MMP13, MMP8, MMP1
4721-hydroxylase deficiency10.0
48neurofibromatosis10.0
49chorioangioma10.0
50autoimmune thyroiditis10.0

Graphical network of the top 20 diseases related to Ovarian Cyst:



Diseases related to ovarian cyst

Symptoms for Ovarian Cyst

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Drugs & Therapeutics for Ovarian Cyst

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Ovarian Cyst

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Anatomical Context for Ovarian Cyst

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34MalaCards
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MalaCards organs/tissues related to Ovarian Cyst:

34
Ovary, Uterus, Breast, Pituitary, Colon, Endothelial, Kidney, Appendix, Bone, Liver, Small intestine, Heart, Brain, Thyroid

Animal Models for Ovarian Cyst or affiliated genes

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Publications for Ovarian Cyst

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53PubMed
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Articles related to Ovarian Cyst:

(show top 50)    (show all 535)
idTitleAuthorsYear
1
Differences in omega-3 and fatty acid profiles between patients with endometriosis and those with a functional ovarian cyst. (23919858)
2013
2
Mullerian cyst of the uterus misdiagnosed as ovarian cyst on pelvic sonography. (23949900)
2013
3
Massive ovarian cyst and sudden death. (21659835)
2012
4
Congenital ovarian cyst: a report of two cases. (22923930)
2012
5
A huge ovarian cyst in a hysterectomized bitch. (21535241)
2011
6
A study of ovarian cyst in a tertiary hospital of Kathmandu valley. (21991700)
2011
7
"Laparoscopic excision of a large ovarian cyst herniating into the inguinal canal: a rare presentation". (21857466)
2011
8
Autoamputation of an ovarian cyst: a case report. (20120906)
2009
9
Conservative laparoscopic treatment of a benign giant ovarian cyst in a young woman. (19489679)
2009
10
Two-port laparoscopic management of an autoamputated ovarian cyst in a newborn. (18439514)
2008
11
Stillbirth due to placental hypoperfusion after salpingo-oophorectomy for an ovarian cyst. (17666636)
2007
12
Gasless laparoscopic surgery for ovarian cyst in a second trimester pregnant patient with a ventricular septal defect. (18097327)
2007
13
Suppression of a postmenopausal ovarian cyst with goserelin. (16147672)
2004
14
Neonatal ovarian cysts: management with reference to magnetic resonance imaging. (14719514)
2004
15
Comparison of HGF (hepatocyte growth factor) levels of epithelial ovarian cancer cyst fluids with benign ovarian cysts. (14675313)
2003
16
Torsion of para-ovarian cyst: a cause of acute abdomen. (12944694)
2003
17
Laparoscopic extirpation of a giant ovarian cyst. (11967707)
2002
18
Suprarenal vena caval thrombosis and pulmonary embolism associated with a benign ovarian cyst. (12554279)
2002
19
Ovarian cyst in a premature infant treated with spironolactone. (11607853)
2001
20
"Daughter cyst" sign: a sonographic finding of ovarian cyst in neonates, infants, and young children. (10749241)
2000
21
Laparoscopic excision of a mesenteric cyst diagnosed preoperatively as an ovarian cyst. (10924644)
2000
22
A case of huge ovarian cyst of 21-year-old young woman. (10540532)
1999
23
Elevated circulating estradiol level in neonatal ovarian cyst. (10555729)
1999
24
Prolapsed ovarian cyst through cervical stump: a rare complication of a subtotal hysterectomy. (15512157)
1998
25
Sonographically guided aspiration of ovarian cyst with simple appearance. (8683664)
1996
26
Left ovarian cyst and right streak ovary in a neonate with a normal karyotype. Report of a case of neonatal Slotnick-Goldfarb syndrome or recessive gonadal dysgenesis. (8040851)
1994
27
The largest ovarian cyst in Songklanagarind Hospital: a case report. (7876767)
1994
28
Cytologic examination of ovarian cyst fluid for the distinction between benign and malignant tumors. (8355950)
1993
29
Ciliated bodies in ovarian cyst aspirates. (8328243)
1993
30
Ovarian cyst causing massive hydronephrosis: report of a case. (2082745)
1990
31
Perinatal ultrasound casebook. In utero diagnosis of fetal ovarian cyst. (2651598)
1989
32
Oxidation products of ovarian cyst mucins. Characterisation by density-gradient analysis. (3191512)
1988
33
Plasma concentrations of beta-carotene and vitamin A in cows with ovarian cyst. (3820929)
1986
34
Characterization of the oligosaccharide alditols from ovarian cyst mucin glycoproteins of blood group A using high pressure liquid chromatography (HPLC) and high field 1H NMR spectroscopy. (3003076)
1986
35
Conformations of blood group H-active oligosaccharides of ovarian cyst mucins. (4092088)
1985
36
A tubo-ovarian cyst, paraovarian cysts and lesions of the oviduct in the mare. (16031094)
1985
37
Ectopic teeth in an ovarian cyst. (6580603)
1983
38
An ovarian cyst infected with Salmonella typhi. Case report. (6871137)
1983
39
Ovarian gonadotropin receptors during experimental ovarian cyst formation in the rat. (6269663)
1981
40
Ovarian cyst presenting in the neonatal period. (5475781)
1970
41
Huge ovarian cyst with torsion in a newborn infant. (5773901)
1969
42
Ruptured ovarian cyst in the newborn. (5681672)
1968
43
An ovarian cyst: a case report. (6052093)
1967
44
Giant ovarian cyst and the supine hypotensive syndrome. (5946532)
1966
45
Sigmoid volvulus associated with torsion or an ovarian cyst. (14016557)
1963
46
Ovarian cyst with torsion and rupture in an infant. (13514553)
1958
47
A large ovarian cyst. (13279484)
1955
48
Twisted ovarian cyst in a newborn infant. (14822064)
1951
49
Pregnancy complicated by a malignant ovarian cyst. (15422432)
1950
50
Ruptured ovarian cyst as a cause of massive intraabdominal hemorrhage; report of five cases. (15399002)
1950

Variations for Ovarian Cyst

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Expression for genes affiliated with Ovarian Cyst

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ovarian Cyst

Search GEO for disease gene expression data for Ovarian Cyst.

Pathways for genes affiliated with Ovarian Cyst

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51PathCards, 61Thomson Reuters, 39NCBI BioSystems Database, 56Reactome, 13EMD Millipore, 54QIAGEN
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Compounds for genes affiliated with Ovarian Cyst

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46Novoseek, 25HMDB, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 52PharmGKB, 3BitterDB
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Compounds related to Ovarian Cyst according to GeneCards/GeneDecks:

(show all 40)
idCompoundScoreTop Affiliating Genes
1barbiturate469.9MMP8, MMP13
2amide469.8MMP13, MMP8
3p002469.7MMP8, MMP13
42-cyano-3,12-dioxoolean-1,9-dien-28-oic acid469.7MMP1, MMP13
5thps469.7MMP1, MMP13
6thermolysin469.7MMP1, MMP13
7sulfonamide469.7MMP1, MMP13
8hydroxyproline46 25 1211.7MMP1, MMP13
9procollagen469.7MMP1, MMP13
10aprotinin46 1210.6MMP1, MMP13
11sp 60012546 6210.6MMP13, MMP1
12gf 109203x46 6210.6MMP1, MMP13
13prednisolone46 30 1211.5MMP1, MMP13
14egcg469.5MMP1, MMP13
15tgf beta1469.4MMP13, MMP1
16herbimycin a46 6210.4MMP1, MMP13
17hyaluronic acid46 2510.3MMP1, MMP13
18prostaglandin469.3MMP1, MMP13
19(4-aminophenyl)mercuric acetate469.3MMP1, MMP8, MMP13
20clodronate46 52 1211.3MMP13, MMP8, MMP1
21uk 383367629.3MMP13, MMP8, MMP1
22gi 254023x629.3MMP13, MMP8, MMP1
23gm 6001629.3MMP13, MMP8, MMP1
24hydroxamate469.3MMP1, MMP8, MMP13
25marimastat46 62 1211.3MMP13, MMP8, MMP1
26alendronate46 52 1211.3MMP1, MMP8, MMP13
27batimastat46 62 1211.3MMP13, MMP8, MMP1
28doxycycline46 1210.3MMP13, MMP8, MMP1
29tetracycline46 1210.3MMP13, MMP8, MMP1
30glycosaminoglycan469.2MMP1, MMP8, MMP13
31genistein46 30 62 3 25 1214.2MMP13, MMP8, MMP1
32pge2469.2MMP1, MMP8, MMP13
33oligonucleotide469.2MMP1, MMP8, MMP13
34vegf469.1MMP1, MMP8, MMP13
35zinc46 2510.1MMP13, MMP8, MMP1
36curcumin469.0MMP1, MMP13
37cysteine468.8MMP13, MMP8, MMP1, PRSS2
38serine468.8MMP13, MMP8, MMP1, PRSS2
39retinoic acid46 259.8MMP13, MMP8, MMP1
40calcium46 52 25 1211.6MMP13, MMP8, MMP1, PRSS2

GO Terms for genes affiliated with Ovarian Cyst

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17Gene Ontology
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Cellular components related to Ovarian Cyst according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.1PRSS2, MMP8, MMP13
2proteinaceous extracellular matrixGO:0055788.8MMP1, MMP8, MMP13
3extracellular regionGO:0055768.2MMP13, MMP8, MMP1, PRSS2

Biological processes related to Ovarian Cyst according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ovarian follicle developmentGO:0015419.1NOBOX, FOXL2
2collagen catabolic processGO:0305748.5PRSS2, MMP1, MMP8, MMP13
3extracellular matrix disassemblyGO:0226178.5MMP13, MMP8, MMP1, PRSS2
4proteolysisGO:0065088.4MMP13, MMP8, MMP1, PRSS2
5extracellular matrix organizationGO:0301988.2PRSS2, MMP1, MMP8, MMP13

Molecular functions related to Ovarian Cyst according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1serine-type endopeptidase activityGO:0042529.6PRSS2, MMP8
2metalloendopeptidase activityGO:0042228.8MMP1, MMP8, MMP13
3calcium ion bindingGO:0055098.2PRSS2, MMP1, MMP8, MMP13

Products for genes affiliated with Ovarian Cyst

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  • Proteins
  • Lysates
  • Antibodies

Sources for Ovarian Cyst

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet