MCID: OVR048
MIFTS: 41

Ovarian Cystadenoma malady

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Summaries for Ovarian Cystadenoma

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Wikipedia:65 Ovarian cystadenoma is a cystic benign tumor of the ovary. Two types are recognized: serous and mucinous. more...

MalaCards based summary: Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to cystadenoma and ovarian cancer. An important gene associated with Ovarian Cystadenoma is SELE (selectin E), and among its related pathways are Development VEGF signaling and activation and ATF-2 transcription factor network. The compounds 8-chloro-camp and pd153035 have been mentioned in the context of this disorder. Affiliated tissues include ovary and bone, and related mouse phenotypes are immune system and integument.

Aliases & Classifications for Ovarian Cystadenoma

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Ovarian Cystadenoma, Aliases & Descriptions:

Name: Ovarian Cystadenoma 8 10 44 62
Simple Cystoma of the Ovary 8 62
 
Simple Cystoma of Ovary 8 62
Cystoma Serosum Simplex 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:3269
SNOMED-CT57 198297004
NCIt39 C4060

Related Diseases for Ovarian Cystadenoma

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Diseases related to Ovarian Cystadenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 37)
idRelated DiseaseScoreTop Affiliating Genes
1cystadenoma31.6CLU, BRCA1, AREG
2ovarian cancer29.3TGFA, CLDN3, CLDN4, CLU, BRCA1, MUC16
3mucinous ovarian cystadenoma10.5
4leukostasis10.5SELE
5myxedema10.4LGR6
6cystadenocarcinoma10.3MUC16, AREG
7malignant mesothelioma10.2AREG, MUC16
8anaplastic large cell lymphoma10.2CLU, MUC16
9cervical cancer10.2CLU, MUC16, AREG
10deficiency anemia10.2AREG, MUC16, BRCA1
11bladder carcinoma10.1AREG, CLU, TGFA
12skin disease10.1TGFA, SELE, AREG
13sickle cell disease10.1BRCA1, SELE
14breast cancer10.1AREG, BRCA1, TGFA
15congenital adrenal hyperplasia10.1
16tuberculous peritonitis10.1
17zollinger-ellison syndrome10.1
18leiomyomatosis10.1
19peritonitis10.1
20struma ovarii10.1
21papillary carcinoma10.1CLDN3, CLDN4, MUC16
22psoriasis10.1TGFA, SELE, AREG
23acanthosis nigricans10.0TGFA, LMNA
24pancreatic cancer10.0AREG, BRCA1, CLDN4, TGFA
25werner syndrome10.0LMNA, BRCA1
26colorectal cancer10.0CLU, BRCA1, MUC16, AREG
27gastric adenocarcinoma9.9TGFA, CLDN3, CLDN4, MUC16
28coronary artery anomaly9.9LMNA, CLU, SELE
29stomach cancer9.9TGFA, CLDN3, CLDN4, AREG
30endometrial carcinoma9.9TGFA, CLDN3, BRCA1, MUC16
31colonic benign neoplasm9.9TGFA, SELE, CLU, BRCA1, AREG
32adenoma9.8AREG, BRCA1, CLDN4, CLDN3, TGFA
33lung cancer9.8TGFA, LMNA, MUC16, AREG
34retinoblastoma9.7LMNA, BRCA1, CLU
35tongue squamous cell carcinoma9.7TGFA, CLDN3, CLDN4, CLU, MUC16, AREG
36adenocarcinoma9.5TGFA, CLDN3, CLDN4, CLU, BRCA1, MUC16
37prostate cancer9.5TGFA, CLDN3, CLDN4, CLU, BRCA1, MUC16

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to ovarian cystadenoma

Symptoms for Ovarian Cystadenoma

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Drugs & Therapeutics for Ovarian Cystadenoma

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Drug clinical trials:

Search ClinicalTrials for Ovarian Cystadenoma

Search NIH Clinical Center for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

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Anatomical Context for Ovarian Cystadenoma

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MalaCards organs/tissues related to Ovarian Cystadenoma:

32
Ovary, Bone

Animal Models for Ovarian Cystadenoma or affiliated genes

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MGI Mouse Phenotypes related to Ovarian Cystadenoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.4AREG, LMNA, BRCA1, CLU, SELE, TGFA
2MP:00107718.4TGFA, SELE, BRCA1, LMNA, AREG
3MP:00053858.3AREG, LMNA, BRCA1, CLU, SELE, TGFA

Publications for Ovarian Cystadenoma

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Articles related to Ovarian Cystadenoma:

(show all 30)
idTitleAuthorsYear
1
Bilateral ovarian cystadenoma in a geriatric African elephant (Loxodonta africana). (25000708)
2014
2
Presacral epidermoid cyst in an elderly female, mistaken for ovarian cystadenoma. (25404834)
2014
3
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. (21792894)
2012
4
Abnormal A^A^A^I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. (22310273)
2012
5
A woman with salt-wasting congenital adrenal hyperplasia presenting with a mucinous ovarian cystadenoma during pregnancy. (21921381)
2011
6
Cutaneous and uterine leiomyomatosis and ovarian cystadenoma associated with deficiency of fumarate hydratase. (24396716)
2011
7
Lamin C protein deficiency in the primary fibroblasts from a new laminopathy case with ovarian cystadenoma. (20819672)
2010
8
Abnormal iodine-131 uptake in a benign mucinous ovarian cystadenoma mimicking struma ovarii. (17179812)
2007
9
Rapidly growing bilateral ovarian cystadenoma in a 6-year-old girl: case report and literature review. (16472727)
2006
10
Ovarian cystadenoma as a characteristic feature of families with hereditary ovarian cancers unassociated with BRCA1 and BRCA2 mutations. (15131356)
2004
11
Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. (12855632)
2003
12
Tuberculous peritonitis with sonographic features of an ovarian cystadenoma. (14510274)
2003
13
Massive ovarian cystadenoma detected solely on the blood-pool phase of a bone scan. (12045453)
2002
14
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. (9563228)
1998
15
Establishment of long-term in vitro cultures of human ovarian cystadenomas and LMP tumors and examination of their spectrum of expression of matrix-degrading proteinases. (9441775)
1997
16
Extremely high levels of CA19-9 and CA125 antigen in benign mucinous ovarian cystadenoma. (7508878)
1994
17
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. (1382586)
1992
18
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). (1867577)
1991
19
"Pseudoascites" secondary to an amylase-producing serous ovarian cystadenoma. A case study. (2479672)
1989
20
Borderline ovarian cystadenoma. Spontaneous rupture and reaccumulation documented by ultrasound. (3286886)
1988
21
Ovarian cystadenoma with stromal cell hyperplasia and postmenopausal virilization: a case report. (3169360)
1988
22
A plasminogen activator from benign ovarian cystadenoma: partial purification and characterization. (3961743)
1986
23
Cystic parametrial fibroids mimicking ovarian cystadenoma. (6726872)
1984
24
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. (7365959)
1980
25
A benign serous ovarian cystadenoma studied by chromosome and quantitative DNA analysis. (274883)
1977
26
Virilization in pregnancy associated with an ovarian cystadenoma. (4416869)
1974
27
Acute abdominal symptoms due to torsion of an ovarian cystadenoma in a centenarian. (5053461)
1972
28
Chromosomal aberrations in an ovarian cystadenoma. (4185609)
1969
29
Free and conjugated estrogens of an ovarian cystadenoma and granulosa cell tumor. (4284085)
1965
30
PSEUDOMYXOMA PERITONAEI SECONDARY TO OVARIAN CYSTADENOMA. (20317773)
1930

Variations for Ovarian Cystadenoma

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Expression for genes affiliated with Ovarian Cystadenoma

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Expression patterns in normal tissues for genes affiliated with Ovarian Cystadenoma

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Pathways for genes affiliated with Ovarian Cystadenoma

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Pathways related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades60
9.9BRCA1, SELE
29.9BRCA1, SELE
39.0CLDN4, CLDN3, SELE

Compounds for genes affiliated with Ovarian Cystadenoma

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Compounds related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idCompoundScoreTop Affiliating Genes
18-chloro-camp4410.0TGFA, AREG
2pd153035449.9AREG, TGFA
3sialic acid449.9SELE, CLU, MUC16
4cyclophosphamide44 50 1111.9MUC16, BRCA1, SELE
5sn 3844 6110.8TGFA, AREG
6topotecan44 1110.8TGFA, BRCA1, MUC16
7methotrexate50 44 1111.7BRCA1, SELE, TGFA
85fluorouracil449.7TGFA, SELE, BRCA1
9mitomycin c449.7AREG, BRCA1, TGFA
10dihydrotestosterone44 28 24 1112.7TGFA, CLU, AREG
11ochratoxin a44 6110.6CLDN4, CLDN3
12matrigel449.6CLU, SELE, TGFA
13calcitriol44 61 24 1112.6AREG, CLU, TGFA
14cetuximab44 50 1111.6TGFA, AREG
15folate449.6BRCA1, CLU, SELE, TGFA
16n acetylcysteine449.6AREG, CLU, SELE
17etoposide44 50 61 1112.6TGFA, SELE, CLU, BRCA1
18tamoxifen44 50 28 1112.6TGFA, SELE, CLU, BRCA1
19lactate449.5TGFA, SELE, CLU, MUC16
20gnrh449.5TGFA, CLU, LGR6
21cisplatin44 50 61 1112.5AREG, MUC16, BRCA1, CLU
22paclitaxel44 50 1111.5MUC16, BRCA1, CLU, TGFA
23paraffin449.5TGFA, CLU, BRCA1, MUC16
244-hydroxytamoxifen449.5TGFA, CLU, BRCA1, AREG
25polysaccharide449.5TGFA, SELE, CLU, AREG
26epinephrine44 24 1111.5TGFA, SELE, AREG
27actinomycin d449.5AREG, CLU, SELE, TGFA
28enterotoxin449.4CLDN4, CLDN3
29creatinine449.4MUC16, LMNA, SELE, TGFA
30h2o2449.4TGFA, CLU, BRCA1, MUC16
31thymidine44 2410.4TGFA, CLU, BRCA1, AREG
32norepinephrine44 24 1111.3AREG, SELE, TGFA
33dexamethasone44 50 28 1112.3CLDN4, CLU, MUC16, AREG
34fibrinogen449.3SELE, CLU, MUC16
35oligonucleotide449.3AREG, BRCA1, CLU, TGFA
36doxorubicin44 50 1111.3TGFA, SELE, CLU, BRCA1, MUC16
37heparin44 28 24 1112.2TGFA, SELE, CLU, BRCA1, AREG
38cycloheximide449.2AREG, BRCA1, CLU, SELE, TGFA
39estradiol44 24 1111.1TGFA, CLU, BRCA1, MUC16, AREG
40retinoic acid44 2410.1TGFA, CLU, BRCA1, LMNA, AREG
41alanine449.0LMNA, BRCA1, SELE, TGFA
42progesterone44 28 61 24 1112.7TGFA, CLDN4, CLU, BRCA1, MUC16, AREG
43cholesterol44 28 24 1111.7LGR6, LMNA, CLU, CLDN3, SELE
44steroid448.6TGFA, CLU, BRCA1, MUC16, LGR6, AREG
45testosterone44 61 24 1111.3TGFA, SELE, CLU, BRCA1, MUC16, LGR6
46calcium44 50 24 1111.3CLDN3, CLDN4, CLU, BRCA1, LMNA, AREG
47estrogen448.2TGFA, CLDN4, CLU, BRCA1, MUC16, LGR6
48tyrosine448.2TGFA, CLDN4, CLU, BRCA1, MUC16, LGR6
49vegf448.0TGFA, SELE, CLDN3, CLU, BRCA1, MUC16
50serine447.6AREG, TGFA, SELE, CLDN4, CLU, BRCA1

GO Terms for genes affiliated with Ovarian Cystadenoma

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Cellular components related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1perinuclear region of cytoplasmGO:0484719.1LMNA, CLU, SELE, TGFA
2extracellular spaceGO:0056157.7CKLF, TGFA, SELE, CLU, MUC16, CMTM5

Biological processes related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-independent cell-cell adhesionGO:0163389.3CLDN4, CLDN3

Molecular functions related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:0051989.0LMNA, CLDN4, CLDN3
2transmembrane signaling receptor activityGO:0048888.2LGR6, CLDN4, CLDN3, SELE

Products for genes affiliated with Ovarian Cystadenoma

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Sources for Ovarian Cystadenoma

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3CDC
13ExPASy
14FMA
22GTR
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25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
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58SNOMED-CT via Orphanet
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