MCID: OVR048
MIFTS: 34

Ovarian Cystadenoma malady

Summaries for Ovarian Cystadenoma

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33MalaCards
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MalaCards: Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to cystadenoma and mucinous ovarian cystadenoma. An important gene associated with Ovarian Cystadenoma is FH (fumarate hydratase), and among its related pathways is Cell adhesion molecules (CAMs). The compounds cycloheximide and sialic acid have been mentioned in the context of this disorder. Related mouse phenotype renal/urinary system.

Aliases & Classifications for Ovarian Cystadenoma

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 40NCIt, 57SNOMED-CT
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Aliases & Descriptions:

ovarian cystadenoma 8 10 45 61
simple cystoma of the ovary 8
simple cystoma of ovary 8
cystoma serosum simplex 8


External Ids:

Disease Ontology8 DOID:3269
SNOMED-CT57 198297004
NCIt40 C4060

Related Diseases for Ovarian Cystadenoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Ovarian Cystadenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1cystadenoma31.2BRCA1, AREG, CLU
2mucinous ovarian cystadenoma10.4
3tuberculous peritonitis10.1
4congenital adrenal hyperplasia10.1
5benign struma ovarii10.1
6zollinger-ellison syndrome10.1
7protein c deficiency10.1
8struma ovarii10.1
9fumarate hydratase deficiency10.1
10endometriosis10.0MUC16
11peritonitis10.0MUC16
12kidney cancer10.0FH
13wilms tumor10.0AREG
14leiomyoma10.0FH
15leiomyosarcoma10.0FH, MUC16
16synovitis10.0SELE
17colon adenocarcinoma10.0AREG, TGFA
18hemangioma10.0CLU
19ovarian cancer10.0MUC16, BRCA1
20familial colorectal cancer10.0BRCA1, FH
21myxedema10.0LGR6
22deficiency anemia10.0BRCA1, AREG, MUC16
23myopathy10.0LMNA
24leukemia10.0BRCA1, AREG
25benign mesothelioma10.0AREG, CLDN3, MUC16
26papillary carcinoma10.0CLDN4, MUC16, CLDN3
27peritoneal carcinoma10.0BRCA1
28hypogonadism10.0LGR6
29infertility10.0CLU, LGR6
30familial adenomatous polyposis10.0BRCA1, CLU
31cervical cancer10.0MUC16, CLU, AREG
32colorectal cancer10.0BRCA1, CLU, MUC16, AREG
33breast cancer10.0AREG, BRCA1, TGFA
34pancreatic cancer10.0CLDN4, AREG, BRCA1, TGFA
35skin disease10.0TGFA, SELE, AREG
36obesity10.0SELE, LMNA
37gastric adenocarcinoma10.0CLDN3, CLDN4, MUC16, TGFA
38bladder carcinoma10.0TGFA, CLU, AREG, BRCA1
39endometrial carcinoma10.0CLDN3, BRCA1, MUC16, TGFA
40stomach cancer10.0AREG, CLDN3, TGFA, CLDN4
41adenoma10.0AREG, CLDN3, CLDN4, BRCA1, TGFA
42acanthosis nigricans10.0TGFA, LMNA
43squamous cell carcinoma10.0CLDN3, CLDN4, MUC16, CLU, TGFA, AREG
44adenocarcinoma10.0CLDN3, TGFA, CLU, CLDN4, BRCA1, MUC16
45colon cancer10.0CLDN3, TGFA, SELE, LMNA, AREG
46lung cancer10.0MUC16, AREG, TGFA, LMNA, AHRR
47prostate cancer10.0CLDN4, CLDN3, TGFA, MUC16, CLU, AREG

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to ovarian cystadenoma

Clinical Features for Ovarian Cystadenoma

Drugs & Therapeutics for Ovarian Cystadenoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Ovarian Cystadenoma

Drug clinical trials:

Search ClinicalTrials for Ovarian Cystadenoma

Search NIH Clinical Center for Ovarian Cystadenoma

Search CenterWatch for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

Anatomical Context for Ovarian Cystadenoma

Animal Models for Ovarian Cystadenoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Ovarian Cystadenoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053679.0LMNA, CLU, CLDN4, FH, BRCA1

Publications for Ovarian Cystadenoma

Sources:
51PubMed
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Articles related to Ovarian Cystadenoma:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
MRI in differentiating ovarian borderline from benign mucinous cystadenoma: Pathological correlation. (24123278)
2014
2
Acute abdominal distension in early pregnancy from torted ovarian serous cystadenoma. (24359062)
2014
3
Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman. (24005462)
2013
4
Linear and micronodular neuroendocrine cell hyperplasia in an ovarian mucinous cystadenoma. (23891137)
2013
5
Successful Vaginal Delivery despite a Huge Ovarian Mucinous Cystadenoma Complicating Pregnancy: A Case Report. (24293789)
2013
6
Ovarian mucinous cystadenoma coexisting with benign Brenner tumor: MR imaging findings. (22476372)
2013
7
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. (21792894)
2012
8
Benign ovarian serous cystadenoma mimicking papillary thyroid carcinoma metastasis on I-131 SPECT/CT. (22474878)
2012
9
Abnormal A^A^A^I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. (22310273)
2012
10
A woman with salt-wasting congenital adrenal hyperplasia presenting with a mucinous ovarian cystadenoma during pregnancy. (21921381)
2011
11
Ovarian mucinous cystadenoma in a gray brocket deer (Mazama gouazoupira). (21908297)
2011
12
Florid cystic endosalpingiosis with extensive peritoneal involvement and concurrent bilateral ovarian serous cystadenoma. (22085078)
2011
13
Lamin C protein deficiency in the primary fibroblasts from a new laminopathy case with ovarian cystadenoma. (20819672)
2010
14
A massive ovarian mucinous cystadenoma: a case report. (20222970)
2010
15
Ovarian clear cell carcinoma arising in a mucinous cystadenoma. (19851211)
2009
16
The co-location of an ovarian clear cell carcinoma and mucinous cystadenoma. (19291542)
2009
17
Giant ovarian serous cystadenoma in a postmenopausal woman: a case report. (19830023)
2009
18
Complex serous cystadenoma with ovarian stroma of the fallopian tube ampulla presenting surgically. (19697223)
2009
19
Bilateral ovarian mucinous cystadenoma in an adolescent presenting as abdominal compartment syndrome. (18164120)
2008
20
A huge ovarian mucinous cystadenoma in a 14-year-old premenarchal girl: review on ovarian mucinous tumor in premenarchal girls. (18312801)
2008
21
Huge primary retroperitoneal mucinous cystadenoma of borderline malignancy mimicking an ovarian mass: case report and review. (18751411)
2008
22
Small bowel volvulus caused by re-implantation and growth of remnant tissue from a previously excised ovarian mucinous cystadenoma. (17627695)
2007
23
Serous cystadenoma of the epididymis of common epithelial ovarian type: case report with an immunohistochemical study. (17318978)
2006
24
Ovarian neoplasm composed of an insular carcinoid tumor and a borderline mucinous cystadenoma arising in a mature cystic teratoma: a case report. (17290604)
2006
25
Massive ovarian edema associated with ovarian serous cystadenoma: a case report and review of the literature. (16515615)
2006
26
Rapidly growing bilateral ovarian cystadenoma in a 6-year-old girl: case report and literature review. (16472727)
2006
27
Halving of body weight: a case of an ovarian mucinous cystadenoma. (16550979)
2006
28
Ovarian mucinous cystadenoma with extended calcification in an 11-year-old girl: case report and review of the literature. (17089585)
2006
29
Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells. (15797026)
2005
30
Ovarian serous cystadenoma with mural nodules of genital rhabdomyoma. (15892006)
2005
31
Intra-abdominal ovarian-type mucinous cystadenoma associated with fallopian tube-like structure and aberrant epididymal tissue in a male patient. (16112012)
2005
32
Ovarian serous cystadenoma with associated genital rhabdomyoma. (16260279)
2005
33
Molecular genetic analysis of ovarian serous cystadenomas. (15077125)
2004
34
Sarcoma-like mural nodule in an ovarian mucinous cystadenoma: a case report. (16295477)
2004
35
Massive ovarian mucinous cystadenoma in a 14-year-old girl. (14675997)
2004
36
Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. (12855632)
2003
37
Tuberculous peritonitis with sonographic features of an ovarian cystadenoma. (14510274)
2003
38
Estrogen-producing ovarian mucinous cystadenomas in postmenopausal women. (10854548)
2000
39
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. (9563228)
1998
40
Establishment of long-term in vitro cultures of human ovarian cystadenomas and LMP tumors and examination of their spectrum of expression of matrix-degrading proteinases. (9441775)
1997
41
Neuroendocrine carcinoma arising in an ovarian mucinous cystadenoma. (8786207)
1996
42
Ovarian serous cystadenoma associated with Sertoli-Leydig cell tumor--a case report. (8703377)
1996
43
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
44
Unique combination of an ovarian gonadoblastoma, dysgerminoma, and mucinous cystadenoma in a patient with Turner's syndrome: a cytogenetic and molecular analysis. (7928059)
1994
45
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. (1382586)
1992
46
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). (1867577)
1991
47
Borderline ovarian cystadenoma. Spontaneous rupture and reaccumulation documented by ultrasound. (3286886)
1988
48
Zollinger-Ellison syndrome due to a gastrin secreting ovarian mucinous cystadenoma. Case report. (4027214)
1985
49
A benign serous ovarian cystadenoma studied by chromosome and quantitative DNA analysis. (274883)
1977
50
Virilization in pregnancy associated with an ovarian cystadenoma. (4416869)
1974

Genetic Variations for Ovarian Cystadenoma

Expression for genes affiliated with Ovarian Cystadenoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ovarian Cystadenoma

Search GEO for disease gene expression data for Ovarian Cystadenoma.

Pathways for genes affiliated with Ovarian Cystadenoma

Sources:
30KEGG
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Pathways related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3SELE, CLDN4, CLDN3

Compounds for genes affiliated with Ovarian Cystadenoma

Sources:
45Novoseek, 11DrugBank, 24HMDB, 60Tocris Bioscience, 50PharmGKB, 29IUPHAR
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Compounds related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

(show all 34)
idCompoundScoreTop Affiliating Genes
1cycloheximide4510.6BRCA1
2sialic acid4510.4SELE
3estrogen4510.3LGR6
4estradiol45 11 2412.2MUC16, CLU
58-chloro-camp459.9TGFA, AREG
6ochratoxin a45 6010.8CLDN3, CLDN4
7topotecan45 1110.8TGFA, MUC16, BRCA1
8pd153035459.6TGFA, AREG
9mitomycin c459.6TGFA, AREG, BRCA1
10folate459.6TGFA, SELE, CLU, BRCA1
11etoposide45 50 60 1112.5BRCA1, CLU, SELE, TGFA
12tamoxifen45 50 29 1112.5BRCA1, CLU, SELE, TGFA
13cyclophosphamide45 50 1111.5SELE, MUC16, BRCA1
144-hydroxytamoxifen459.5BRCA1, AREG, CLU, TGFA
15dihydrotestosterone45 29 11 2412.4TGFA, CLU, AREG
16proline459.4BRCA1, FH, CLU, TGFA
17paclitaxel45 50 1111.4BRCA1, MUC16, CLU, TGFA
18polysaccharide459.4TGFA, SELE, CLU, AREG
19paraffin459.3BRCA1, MUC16, CLU, TGFA
20actinomycin d459.3TGFA, SELE, CLU, AREG
21cisplatin45 50 60 1112.3BRCA1, AREG, MUC16, CLU
22doxorubicin45 50 1111.2BRCA1, MUC16, CLU, SELE, TGFA
23lactate459.2FH, MUC16, CLU, SELE, TGFA
24creatinine459.2FH, MUC16, LMNA, SELE, TGFA
25heparin45 29 11 2412.1BRCA1, AREG, CLU, SELE, TGFA
26cholesterol45 29 11 2411.9CLDN3, CLU, LMNA, LGR6, SELE
27thymidine45 249.8BRCA1, AREG, CLU, TGFA
28retinoic acid45 249.8TGFA, LMNA, CLU, AREG, BRCA1
29progesterone45 60 29 11 2412.7BRCA1, AREG, MUC16, CLDN4, CLU, TGFA
30steroid458.6BRCA1, AREG, MUC16, CLU, LGR6, TGFA
31testosterone45 60 11 2411.3TGFA, BRCA1, AREG, MUC16, CLU, LGR6
32vegf458.3BRCA1, AREG, MUC16, CLDN3, CLU, SELE
33tyrosine458.0BRCA1, FH, AREG, MUC16, CLDN4, CLU
34serine457.7BRCA1, AREG, MUC16, CLDN4, CLU, LMNA

GO Terms for genes affiliated with Ovarian Cystadenoma

Sources:
16Gene Ontology
See all sources

Cellular components related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1perinuclear region of cytoplasmGO:0484719.2TGFA, SELE, LMNA, CLU
2extracellular spaceGO:0056157.4TGFA, CKLF, MUC16, CLU, CMTM5, SELE

Biological processes related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-independent cell-cell adhesionGO:0163389.6CLDN4, CLDN3

Molecular functions related to Ovarian Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:0051989.3LMNA, CLDN4, CLDN3
2transmembrane signaling receptor activityGO:0048888.5SELE, LGR6, CLDN4, CLDN3

Products for genes affiliated with Ovarian Cystadenoma

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Sources for Ovarian Cystadenoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet