MCID: OVR048
MIFTS: 34

Ovarian Cystadenoma malady

Summaries for Ovarian Cystadenoma

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Wikipedia:63 Ovarian cystadenoma is a cystic benign tumor of the ovary. Two types are recognized: serous and mucinous. more...

MalaCards based summary: Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to cystadenoma and mucinous ovarian cystadenoma. An important gene associated with Ovarian Cystadenoma is SELE (selectin E), and among its related pathways are Development VEGF signaling and activation and ATF-2 transcription factor network. The compounds 8-chloro-camp and pd153035 have been mentioned in the context of this disorder. Affiliated tissues include ovary and bone, and related mouse phenotypes are immune system and integument.

Aliases & Classifications for Ovarian Cystadenoma

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Ovarian Cystadenoma, Aliases & Descriptions:

Name: Ovarian Cystadenoma 9 11 43 60
Simple Cystoma of the Ovary 9
 
Simple Cystoma of Ovary 9
Cystoma Serosum Simplex 9


External Ids:

Disease Ontology9 DOID:3269
SNOMED-CT55 198297004
NCIt38 C4060

Related Diseases for Ovarian Cystadenoma

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Diseases related to Ovarian Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
idRelated DiseaseScoreTop Affiliating Genes
1cystadenoma31.6CLU, BRCA1, AREG
2mucinous ovarian cystadenoma10.5
3leukostasis10.5SELE
4myxedema10.4LGR6
5cystadenocarcinoma10.3MUC16, AREG
6mesothelioma, somatic10.2AREG, MUC16
7anaplastic large cell lymphoma10.2CLU, MUC16
8cervical cancer, somatic10.1CLU, MUC16, AREG
9deficiency anemia10.1AREG, MUC16, BRCA1
10bladder cancer, somatic10.1AREG, CLU, TGFA
11skin disease10.1TGFA, SELE, AREG
12sickle cell disease10.1BRCA1, SELE
13breast cancer10.1AREG, BRCA1, TGFA
14congenital adrenal hyperplasia10.1
15tuberculous peritonitis10.1
16zollinger-ellison syndrome10.1
17leiomyomatosis10.1
18peritonitis10.1
19struma ovarii10.1
20papillary carcinoma10.1CLDN3, CLDN4, MUC16
21mesothelioma10.1AREG, MUC16, CLDN3
22psoriasis10.1TGFA, SELE, AREG
23acanthosis nigricans10.0TGFA, LMNA
24pancreatic cancer10.0AREG, BRCA1, CLDN4, TGFA
25werner syndrome10.0LMNA, BRCA1
26colorectal cancer10.0CLU, BRCA1, MUC16, AREG
27gastric adenocarcinoma9.9TGFA, CLDN3, CLDN4, MUC16
28coronary artery disease9.9LMNA, CLU, SELE
29stomach cancer9.9TGFA, CLDN3, CLDN4, AREG
30endometrial cancer9.9TGFA, CLDN3, BRCA1, MUC16
31adenoma9.8AREG, BRCA1, CLDN4, CLDN3, TGFA
32lung cancer9.8TGFA, LMNA, MUC16, AREG
33retinoblastoma9.7LMNA, BRCA1, CLU
34tongue squamous cell carcinoma9.7TGFA, CLDN3, CLDN4, CLU, MUC16, AREG
35gastric cancer, somatic9.6TGFA, CLDN3, CLDN4, BRCA1, MUC16, AREG
36adenocarcinoma9.5TGFA, CLDN3, CLDN4, CLU, BRCA1, MUC16
37prostate cancer9.5TGFA, CLDN3, CLDN4, CLU, BRCA1, MUC16
38ovarian cancer, somatic9.3TGFA, CLDN3, CLDN4, CLU, BRCA1, MUC16

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to ovarian cystadenoma

Symptoms for Ovarian Cystadenoma

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Drugs & Therapeutics for Ovarian Cystadenoma

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Drug clinical trials:

Search ClinicalTrials for Ovarian Cystadenoma

Search NIH Clinical Center for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

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Anatomical Context for Ovarian Cystadenoma

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MalaCards organs/tissues related to Ovarian Cystadenoma:

31
Ovary, Bone

Animal Models for Ovarian Cystadenoma or affiliated genes

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MGI Mouse Phenotypes related to Ovarian Cystadenoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.4AREG, LMNA, BRCA1, CLU, SELE, TGFA
2MP:00107718.4TGFA, SELE, BRCA1, LMNA, AREG
3MP:00053858.3AREG, LMNA, BRCA1, CLU, SELE, TGFA

Publications for Ovarian Cystadenoma

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Articles related to Ovarian Cystadenoma:

(show all 31)
idTitleAuthorsYear
1
Bilateral ovarian cystadenoma in a geriatric African elephant (Loxodonta africana). (25000708)
2014
2
Presacral epidermoid cyst in an elderly female, mistaken for ovarian cystadenoma. (25404834)
2014
3
Perioperative management for the removal of a massive ovarian cystadenoma. (25612086)
2013
4
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. (21792894)
2012
5
Abnormal A^A^A^I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. (22310273)
2012
6
A woman with salt-wasting congenital adrenal hyperplasia presenting with a mucinous ovarian cystadenoma during pregnancy. (21921381)
2011
7
Cutaneous and uterine leiomyomatosis and ovarian cystadenoma associated with deficiency of fumarate hydratase. (24396716)
2011
8
Lamin C protein deficiency in the primary fibroblasts from a new laminopathy case with ovarian cystadenoma. (20819672)
2010
9
Abnormal iodine-131 uptake in a benign mucinous ovarian cystadenoma mimicking struma ovarii. (17179812)
2007
10
Rapidly growing bilateral ovarian cystadenoma in a 6-year-old girl: case report and literature review. (16472727)
2006
11
Ovarian cystadenoma as a characteristic feature of families with hereditary ovarian cancers unassociated with BRCA1 and BRCA2 mutations. (15131356)
2004
12
Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. (12855632)
2003
13
Tuberculous peritonitis with sonographic features of an ovarian cystadenoma. (14510274)
2003
14
Massive ovarian cystadenoma detected solely on the blood-pool phase of a bone scan. (12045453)
2002
15
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. (9563228)
1998
16
Establishment of long-term in vitro cultures of human ovarian cystadenomas and LMP tumors and examination of their spectrum of expression of matrix-degrading proteinases. (9441775)
1997
17
Extremely high levels of CA19-9 and CA125 antigen in benign mucinous ovarian cystadenoma. (7508878)
1994
18
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. (1382586)
1992
19
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). (1867577)
1991
20
"Pseudoascites" secondary to an amylase-producing serous ovarian cystadenoma. A case study. (2479672)
1989
21
Borderline ovarian cystadenoma. Spontaneous rupture and reaccumulation documented by ultrasound. (3286886)
1988
22
Ovarian cystadenoma with stromal cell hyperplasia and postmenopausal virilization: a case report. (3169360)
1988
23
A plasminogen activator from benign ovarian cystadenoma: partial purification and characterization. (3961743)
1986
24
Cystic parametrial fibroids mimicking ovarian cystadenoma. (6726872)
1984
25
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. (7365959)
1980
26
A benign serous ovarian cystadenoma studied by chromosome and quantitative DNA analysis. (274883)
1977
27
Virilization in pregnancy associated with an ovarian cystadenoma. (4416869)
1974
28
Acute abdominal symptoms due to torsion of an ovarian cystadenoma in a centenarian. (5053461)
1972
29
Chromosomal aberrations in an ovarian cystadenoma. (4185609)
1969
30
Free and conjugated estrogens of an ovarian cystadenoma and granulosa cell tumor. (4284085)
1965
31
PSEUDOMYXOMA PERITONAEI SECONDARY TO OVARIAN CYSTADENOMA. (20317773)
1930

Variations for Ovarian Cystadenoma

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Expression for genes affiliated with Ovarian Cystadenoma

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Search GEO for disease gene expression data for Ovarian Cystadenoma.

Pathways for genes affiliated with Ovarian Cystadenoma

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Pathways related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades58
9.9BRCA1, SELE
29.9BRCA1, SELE
39.0CLDN4, CLDN3, SELE

Compounds for genes affiliated with Ovarian Cystadenoma

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Compounds related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idCompoundScoreTop Affiliating Genes
18-chloro-camp4310.0TGFA, AREG
2pd153035439.9AREG, TGFA
3sialic acid439.9SELE, CLU, MUC16
4cyclophosphamide43 49 1211.9MUC16, BRCA1, SELE
5sn 3843 5910.8TGFA, AREG
6topotecan43 1210.8TGFA, BRCA1, MUC16
7methotrexate49 43 1211.7BRCA1, SELE, TGFA
85fluorouracil439.7TGFA, SELE, BRCA1
9mitomycin c439.7AREG, BRCA1, TGFA
10dihydrotestosterone43 28 24 1212.7TGFA, CLU, AREG
11ochratoxin a43 5910.6CLDN4, CLDN3
12matrigel439.6CLU, SELE, TGFA
13calcitriol43 59 24 1212.6AREG, CLU, TGFA
14cetuximab43 49 1211.6TGFA, AREG
15folate439.6BRCA1, CLU, SELE, TGFA
16n acetylcysteine439.6AREG, CLU, SELE
17etoposide43 49 59 1212.6TGFA, SELE, CLU, BRCA1
18tamoxifen43 49 28 1212.6TGFA, SELE, CLU, BRCA1
19lactate439.5TGFA, SELE, CLU, MUC16
20gnrh439.5TGFA, CLU, LGR6
21cisplatin43 49 59 1212.5AREG, MUC16, BRCA1, CLU
22paclitaxel43 49 1211.5MUC16, BRCA1, CLU, TGFA
23paraffin439.5TGFA, CLU, BRCA1, MUC16
244-hydroxytamoxifen439.5TGFA, CLU, BRCA1, AREG
25polysaccharide439.5TGFA, SELE, CLU, AREG
26epinephrine43 24 1211.5TGFA, SELE, AREG
27actinomycin d439.5AREG, CLU, SELE, TGFA
28enterotoxin439.4CLDN4, CLDN3
29creatinine439.4MUC16, LMNA, SELE, TGFA
30h2o2439.4TGFA, CLU, BRCA1, MUC16
31thymidine43 2410.4TGFA, CLU, BRCA1, AREG
32norepinephrine43 24 1211.3AREG, SELE, TGFA
33dexamethasone43 49 28 1212.3CLDN4, CLU, MUC16, AREG
34fibrinogen439.3SELE, CLU, MUC16
35oligonucleotide439.3AREG, BRCA1, CLU, TGFA
36doxorubicin43 49 1211.3TGFA, SELE, CLU, BRCA1, MUC16
37heparin43 28 24 1212.2TGFA, SELE, CLU, BRCA1, AREG
38cycloheximide439.2AREG, BRCA1, CLU, SELE, TGFA
39estradiol43 24 1211.1TGFA, CLU, BRCA1, MUC16, AREG
40retinoic acid43 2410.1TGFA, CLU, BRCA1, LMNA, AREG
41alanine439.0LMNA, BRCA1, SELE, TGFA
42progesterone43 28 59 24 1212.7TGFA, CLDN4, CLU, BRCA1, MUC16, AREG
43cholesterol43 28 24 1211.7LGR6, LMNA, CLU, CLDN3, SELE
44steroid438.6TGFA, CLU, BRCA1, MUC16, LGR6, AREG
45testosterone43 59 24 1211.3TGFA, SELE, CLU, BRCA1, MUC16, LGR6
46calcium43 49 24 1211.3CLDN3, CLDN4, CLU, BRCA1, LMNA, AREG
47estrogen438.2TGFA, CLDN4, CLU, BRCA1, MUC16, LGR6
48tyrosine438.2TGFA, CLDN4, CLU, BRCA1, MUC16, LGR6
49vegf438.0TGFA, SELE, CLDN3, CLU, BRCA1, MUC16
50serine437.6AREG, TGFA, SELE, CLDN4, CLU, BRCA1

GO Terms for genes affiliated with Ovarian Cystadenoma

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Cellular components related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1perinuclear region of cytoplasmGO:00484719.1LMNA, CLU, SELE, TGFA
2extracellular spaceGO:00056157.7CKLF, TGFA, SELE, CLU, MUC16, CMTM5

Biological processes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1calcium-independent cell-cell adhesionGO:00163389.3CLDN4, CLDN3

Molecular functions related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:00051989.0LMNA, CLDN4, CLDN3
2transmembrane signaling receptor activityGO:00048888.2LGR6, CLDN4, CLDN3, SELE

Products for genes affiliated with Ovarian Cystadenoma

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Sources for Ovarian Cystadenoma

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3CDC
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25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
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46OMIM via Orphanet
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51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet