MCID: OVR017
MIFTS: 30

Ovarian Cystic Teratoma

Categories: Cancer diseases

Aliases & Classifications for Ovarian Cystic Teratoma

MalaCards integrated aliases for Ovarian Cystic Teratoma:

Name: Ovarian Cystic Teratoma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5118
NCIt 46 C7283
UMLS 69 C1335155

Summaries for Ovarian Cystic Teratoma

MalaCards based summary : Ovarian Cystic Teratoma is related to cystic teratoma and teratoma. An important gene associated with Ovarian Cystic Teratoma is NECTIN2 (Nectin Cell Adhesion Molecule 2), and among its related pathways/superpathways are NF-kappaB Signaling and Cell adhesion molecules (CAMs). Affiliated tissues include b cells, pituitary and colon.

Related Diseases for Ovarian Cystic Teratoma

Diseases related to Ovarian Cystic Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 126)
# Related Disease Score Top Affiliating Genes
1 cystic teratoma 31.6 KRT20 KRT7 NKX2-1
2 teratoma 31.6 KRT20 KRT7 NKX2-1
3 thyroid cancer, anaplastic 10.6 NKX2-1 TG
4 athyreosis 10.6 NKX2-1 TG
5 cystic basal cell carcinoma 10.6 KRT20 KRT7
6 vaginal benign neoplasm 10.5 KRT20 KRT7
7 seminal vesicle adenocarcinoma 10.5 KRT20 KRT7
8 transverse colon cancer 10.5 KRT20 KRT7
9 ovarian large-cell neuroendocrine carcinoma 10.5 KRT20 KRT7
10 vaginal adenoma 10.5 KRT20 KRT7
11 vaginal tubulovillous adenoma 10.5 KRT20 KRT7
12 eyelid neoplasm 10.5 KRT20 KRT7
13 malignant syringoma 10.5 KRT20 KRT7
14 krukenberg carcinoma 10.5 KRT20 KRT7
15 struma ovarii 10.5 NKX2-1 TG
16 large intestine adenocarcinoma 10.5 KRT20 KRT7
17 glandular cystitis 10.5 KRT20 KRT7
18 linitis plastica 10.5 KRT20 KRT7
19 adenoid squamous cell carcinoma 10.5 KRT20 KRT7
20 transient neonatal neutropenia 10.5 FCGR3A FCGR3B
21 malignant teratoma 10.5 NKX2-1 TG
22 eccrine sweat gland neoplasm 10.5 KRT20 KRT7
23 vulval paget's disease 10.5 KRT20 KRT7
24 bladder adenocarcinoma 10.5 KRT20 KRT7
25 bile duct cystadenocarcinoma 10.5 KRT20 KRT7
26 papillary adenoma 10.5 KRT7 NKX2-1
27 intratubular embryonal carcinoma 10.5 KRT20 KRT7
28 ovarian mucinous adenocarcinoma 10.5 KRT20 KRT7
29 thymus adenocarcinoma 10.5 KRT20 KRT7
30 malignant struma ovarii 10.5 NKX2-1 TG
31 gastric diffuse adenocarcinoma 10.4 KRT20 KRT7
32 mucoepidermoid thyroid carcinoma 10.4 CALCA TG
33 meibomian cyst 10.4 KRT20 KRT7
34 rete testis adenocarcinoma 10.4 KRT20 NKX2-1
35 bronchiolo-alveolar adenocarcinoma 10.4 KRT7 NKX2-1
36 bladder lymphoma 10.4 KRT20 KRT7
37 basilar artery insufficiency 10.4 CALCA PVR
38 suppurative thyroiditis 10.4 CALCA TG
39 thyroid sarcoma 10.4 CALCA TG
40 vulva adenocarcinoma 10.4 KRT20 KRT7
41 spastic paraplegia 32, autosomal recessive 10.4 FCGR3A FCGR3B
42 lung acinar adenocarcinoma 10.4 KRT20 KRT7 NKX2-1
43 cystadenofibroma 10.4 KRT20 KRT7 TG
44 small cell carcinoma of the bladder 10.4 KRT20 KRT7 NKX2-1
45 mucinous bronchioloalveolar adenocarcinoma 10.4 KRT20 KRT7 NKX2-1
46 papillary serous adenocarcinoma 10.4 KRT20 KRT7 NKX2-1
47 melanoma 10.4
48 jejunal adenocarcinoma 10.4 KRT20 KRT7
49 atypical follicular adenoma 10.4 CALCA TG
50 ovarian germ cell cancer 10.4 KRT7 NKX2-1 TG

Graphical network of the top 20 diseases related to Ovarian Cystic Teratoma:



Diseases related to Ovarian Cystic Teratoma

Symptoms & Phenotypes for Ovarian Cystic Teratoma

Drugs & Therapeutics for Ovarian Cystic Teratoma

Search Clinical Trials , NIH Clinical Center for Ovarian Cystic Teratoma

Genetic Tests for Ovarian Cystic Teratoma

Anatomical Context for Ovarian Cystic Teratoma

MalaCards organs/tissues related to Ovarian Cystic Teratoma:

38
B Cells, Pituitary, Colon, Thymus

Publications for Ovarian Cystic Teratoma

Articles related to Ovarian Cystic Teratoma:

(show top 50) (show all 64)
# Title Authors Year
1
Melanoma arising in an ovarian cystic teratoma: a systematic review of presentation, treatment, and outcomes. ( 28643027 )
2017
2
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 29016386 )
2017
3
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. ( 26980033 )
2016
4
Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis. ( 24575020 )
2014
5
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. ( 25439346 )
2014
6
Huge Benign Ovarian Cystic Teratoma in a Patient with a History of Hansen's Disease. ( 25210635 )
2014
7
Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in an Ovarian Cystic Teratoma. ( 24715550 )
2014
8
Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma. ( 24584638 )
2014
9
A floating ball: a pathognomonic sign of ovarian cystic teratoma. ( 23764514 )
2013
10
Mature ovarian cystic teratoma (dermoid cyst). ( 22902841 )
2012
11
Intestinal obstruction due to bilateral ovarian cystic teratoma in a pregnant woman: report of a case. ( 21987947 )
2011
12
Conservative surgery in the management of a benign ovarian cystic teratoma presenting as a rectal mass: a case report. ( 21943447 )
2011
13
An unusual growth of ovarian cystic teratoma with multiple floating balls during pregnancy: a case report. ( 20544870 )
2010
14
Ovarian cystic teratoma torsion in pregnancy. ( 20810465 )
2010
15
A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma. ( 19521124 )
2009
16
Spontaneous rupture of benign ovarian cystic teratoma in a premenarcheal girl. ( 19576813 )
2009
17
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 19317266 )
2009
18
Ruptured ovarian cystic teratoma in pregnancy with diffuse peritoneal reaction mimicking advanced ovarian malignancy: a case report. ( 18549490 )
2008
19
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. ( 18581775 )
2008
20
Giant mature ovarian cystic teratoma including more than 300 teeth. ( 18280952 )
2008
21
Ovarian cystic teratoma with a pathognomonic appearance of multiple floating balls: a case report and investigation of common characteristics of the cases in the literature. ( 18304549 )
2008
22
Ruptured ovarian cystic teratoma secondary to blunt abdominal trauma: a very unusual case. ( 17308491 )
2007
23
Floating ball appearance in ovarian cystic teratoma. ( 16972218 )
2006
24
Pathogenesis of balls in mature ovarian cystic teratoma. Report of 3 cases and review of literature. ( 16990711 )
2006
25
Unusual fast-growing ovarian cystic teratoma during pregnancy presenting with intracystic fat "floating balls" appearance. ( 17067585 )
2006
26
Are they spherules of ovarian cystic teratoma or daughter cysts of echinococcosis? ( 17146747 )
2006
27
Ovarian cystic teratoma with primary epithelial cell melanoma. ( 15755005 )
2005
28
Monolateral mature ovarian cystic teratoma. ( 15746800 )
2005
29
Metastatic malignant melanoma arising in a mature ovarian cystic teratoma: a case report and literature review. ( 16343199 )
2005
30
Mature ovarian cystic teratoma with a highly differentiated homunculus: a case report. ( 14745894 )
2004
31
MR and ultrasound imaging of floating globules in mature ovarian cystic teratoma. ( 15205564 )
2004
32
Adenocarcinoma arising from respiratory ciliated epithelium in mature ovarian cystic teratoma. ( 12439559 )
2002
33
Ovarian cystic teratoma: determined phenotypic response of keratocytes and uncommon intracystic floating balls appearance on sonography and computed tomography. ( 12054308 )
2002
34
Small bowel perforation with minor trauma: a rare complication of an ovarian cystic teratoma. ( 12435956 )
2002
35
Unusual "floating balls" appearance of an ovarian cystic teratoma: sonographic and CT findings. ( 11180183 )
2001
36
Primary malignant melanoma in ovarian cystic teratoma. ( 11531299 )
2001
37
Analysis of 20 mature ovarian cystic teratoma cases in postmenopausal women. ( 11780192 )
2001
38
Amelanotic malignant melanoma arising in an ovarian cystic teratoma: a case report. ( 11575655 )
2001
39
Radiology case of the month. Abdominal mass. Bilateral ovarian cystic teratoma. ( 10851824 )
2000
40
Conservative management of ovarian cystic teratoma during pregnancy and labor. ( 10739498 )
2000
41
Thymus tissue in ovarian cystic teratoma: possible clues to its histogenesis. ( 11186178 )
2000
42
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 9743462 )
1998
43
Mature ovarian cystic teratoma with combined squamous cell carcinoma and malignant melanoma. ( 9808441 )
1998
44
Malignant melanoma arising in mature ovarian cystic teratoma (dermoid cyst). Report of two cases and literature analysis. ( 8886884 )
1996
45
Residents' corner. Answer to case of the month #41. Mature ovarian cystic teratoma. ( 8857976 )
1996
46
p53 mutation in carcinomas arising in ovarian cystic teratomas. ( 8548037 )
1995
47
Small-cell epidermoid carcinoma with melanocyte colonization arising in a mature ovarian cystic teratoma. ( 7605174 )
1995
48
Combined microcystic adnexal carcinoma and squamous cell carcinoma arising in the ovarian cystic teratoma--a brief case report. ( 7702793 )
1994
49
Radiology rounds. Ovarian cystic teratoma (ovarian dermoid). ( 7950466 )
1994
50
Malignant melanoma arising in ovarian cystic teratoma. ( 1959792 )
1991

Variations for Ovarian Cystic Teratoma

Expression for Ovarian Cystic Teratoma

Search GEO for disease gene expression data for Ovarian Cystic Teratoma.

Pathways for Ovarian Cystic Teratoma

GO Terms for Ovarian Cystic Teratoma

Cellular components related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.55 ADAM17 B2M CD226 NECTIN2 PVR
2 external side of plasma membrane GO:0009897 9.26 B2M CD226 CD276 FCGR3A
3 cell-cell adherens junction GO:0005913 8.8 CD226 NECTIN2 PVR

Biological processes related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 regulation of receptor activity GO:0010469 9.88 CALCA GAST IFNA2 PRL TG
2 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.63 CD226 NECTIN2 PVR
3 positive regulation of T cell receptor signaling pathway GO:0050862 9.49 CD226 NECTIN2
4 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.43 NECTIN2 PVR
5 cell recognition GO:0008037 9.43 CD226 NECTIN2 PVR
6 positive regulation of mast cell activation GO:0033005 9.4 CD226 NECTIN2
7 susceptibility to T cell mediated cytotoxicity GO:0060370 9.37 NECTIN2 PVR
8 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 9.33 CD226 NECTIN2 PVR
9 positive regulation of immunoglobulin mediated immune response GO:0002891 9.32 CD226 NECTIN2
10 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9.26 CD226 NECTIN2 PVR SLAMF6
11 regulation of immune response GO:0050776 9.17 B2M CD226 CD276 FCGR3A NECTIN2 PVR

Molecular functions related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 IgG binding GO:0019864 9.16 FCGR3A FCGR3B
2 cell adhesion molecule binding GO:0050839 9.13 CD226 NECTIN2 PVR
3 hormone activity GO:0005179 8.92 CALCA GAST PRL TG

Sources for Ovarian Cystic Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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