MCID: OVR097
MIFTS: 21

Ovarian Fibrothecoma malady

Reproductive diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Ovarian Fibrothecoma

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Sources:
51Orphanet, 65UMLS, 28ICD10 via Orphanet
See all sources

Aliases & Descriptions for Ovarian Fibrothecoma:

Name: Ovarian Fibrothecoma 51
 
Ovarian Thecoma 65


Classifications:



Characteristics (Orphanet epidemiological data):

51
ovarian fibrothecoma:
Inheritance: Not applicable; Age of onset: Adult


External Ids:

Orphanet51 314478
ICD10 via Orphanet28 D27

Summaries for Ovarian Fibrothecoma

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MalaCards based summary: Ovarian Fibrothecoma, also known as ovarian thecoma, is related to leiomyomatosis and meige syndrome. An important gene associated with Ovarian Fibrothecoma is ACTC1 (Actin, Alpha, Cardiac Muscle 1), and among its related pathways are Striated Muscle Contraction and Cardiac Progenitor Differentiation. Affiliated tissues include ovary.

Related Diseases for Ovarian Fibrothecoma

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Diseases related to Ovarian Fibrothecoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyomatosis30.1ACTC1, DES
2meige syndrome10.4
3mulibrey nanism10.2
4amenorrhea10.2
5infertility10.2
6retroperitoneal sarcoma10.2
7sarcoma10.2
8adenoma10.1ACTC1, CALB2
9houlston ironton temple syndrome10.1ACTC1, CALB2
10carney complex-trismus-pseudocamptodactyly syndrome10.1ACTC1, CALB2
11necrotizing fasciitis10.1ACTC1, DES
12kidney leiomyosarcoma10.1ACTC1, DES
13lymphangiosarcoma10.1ACTC1, DES
14esophageal lipoma10.1ACTC1, DES
15lung oat cell carcinoma10.1ACTC1, DES
16bladder colonic type adenocarcinoma10.1ACTC1, DES
17benign multicystic peritoneal mesothelioma10.1ACTC1, DES
18psoriasis10.1ACTC1, DES
19internal hemorrhoid10.1ACTC1, DES
20ureter squamous cell carcinoma10.1ACTC1, DES
21infantile recurrent chronic multifocal osteomyolitis10.1ACTC1, DES
22pyosalpinx10.1ACTC1, DES
23autosomal dominant charcot-marie-tooth disease type 2a210.1ACTC1, DES
24glossitis10.1ACTC1, DES
25non-proliferative fibrocystic change of the breast10.0ACTC1, DES
26rete ovarii adenoma10.0ACTC1, DES
27botulism10.0ACTC1, DES
28female reproductive organ cancer10.0ACTC1, DES
29angiomyolipoma10.0ACTC1, DES
30malignant gastric germ cell tumor10.0ACTC1, DES
31autosomal recessive cerebellar ataxia-epilepsy-intellectual disability syndrome due to tud deficiency10.0ACTC1, DES
32pineal region yolk sac tumor10.0ACTC1, DES
33poliomyelitis10.0ACTC1, DES
34developmental dysphasia familial10.0ACTC1, DES
35sublingual gland adenoid cystic carcinoma10.0CALB2, KIT
36in situ pulmonary adenocarcinoma10.0ACTC1, DES
37microscopic colitis10.0ACTC1, KIT
38hole retinal cyst10.0CALB2, KIT
39retinal artery occlusion10.0CALB2, KIT
40dendritic cell thymoma10.0ACTC1, KIT
41rhabdomyomatous mesenchymal hamartoma10.0ACTC1, DES
42acute frontal sinusitis10.0CALB2, KIT
43uterine ligament serous adenocarcinoma10.0ACTC1, DES
44mikulicz disease10.0ACTC1, KIT
45functional gastric disease10.0CALB2, KIT
46hemiplegia10.0ACTC1, KIT
47peripheral retinal degeneration10.0ACTC1, DES
48polymyositis10.0ACTC1, KIT
49gamma-amino butyric acid metabolism disorder10.0DES, KIT
50malignant teratocarcinosarcoma10.0DES, KIT

Graphical network of the top 20 diseases related to Ovarian Fibrothecoma:



Diseases related to ovarian fibrothecoma

Symptoms for Ovarian Fibrothecoma

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Drugs & Therapeutics for Ovarian Fibrothecoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Ovarian Fibrothecoma

Genetic Tests for Ovarian Fibrothecoma

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Anatomical Context for Ovarian Fibrothecoma

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MalaCards organs/tissues related to Ovarian Fibrothecoma:

33
Ovary

Animal Models for Ovarian Fibrothecoma or affiliated genes

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Publications for Ovarian Fibrothecoma

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Articles related to Ovarian Fibrothecoma:

(show all 19)
idTitleAuthorsYear
1
Imaging Findings of Ovarian Fibrothecoma. (26564451)
2015
2
Meigs' syndrome with elevated serum CA 125 level in a case of ovarian fibrothecoma. (25556284)
2014
3
Unilateral ovarian fibrothecoma with menorrhagia. (24763236)
2014
4
Virilizing ovarian fibrothecoma with minor sex cord elements in a 13 year old girl: a rare case. (25635214)
2014
5
Bilateral Ovarian Fibrothecoma Associated with Ascites, Bilateral Pleural Effusion, and Marked Elevated Serum CA-125. (23431489)
2013
6
Bilateral ovarian fibrothecoma. An uncommon cause of a large pelvic mass. (22096681)
2011
7
Meigs' syndrome and virilizing ovarian fibrothecoma complicating pregnancy. A case report and review of the literature. (19675518)
2009
8
Giant malignant ovarian fibrothecoma involved with retroperitoneal structures mimicking a retroperitoneal sarcoma. (18813938)
2009
9
Gynecological tumors in Mulibrey nanism and role for RING finger protein TRIM37 in the pathogenesis of ovarian fibrothecomas. (19329943)
2009
10
Immunohistochemical localization patterns for vimentin and other intermediate filaments in calcified ovarian fibrothecoma. (16965622)
2006
11
Ovarian fibrothecoma associated with Meigs' syndrome and elevated serum CA 125. (17415856)
2004
12
Ovarian fibrothecoma: a benign neoplasm with potential adverse consequences. (14617484)
2003
13
Disseminated leiomyomatosis peritonealis in association with oestrogen secreting ovarian fibrothecoma. (11426907)
2001
14
Tc-99m dicarboxypropane diphosphonate uptake in ovarian fibrothecoma. (10836709)
2000
15
Ovarian fibrothecoma with massive edema. (11019495)
2000
16
Secondary amenorrhea and infertility caused by an inhibin-B-producing ovarian fibrothecoma. (10685524)
2000
17
Numerical and structural chromosome abnormalities in an ovarian fibrothecoma. (7656212)
1995
18
Refractory gestational hypertension due to a renin-secreting ovarian fibrothecoma associated with Gorlin's syndrome. (7999713)
1994
19
Ovarian fibrothecoma: sonographic and histologic findings. (1662660)
1991

Variations for Ovarian Fibrothecoma

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Expression for genes affiliated with Ovarian Fibrothecoma

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Search GEO for disease gene expression data for Ovarian Fibrothecoma.

Pathways for genes affiliated with Ovarian Fibrothecoma

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Pathways related to Ovarian Fibrothecoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3ACTC1, DES
29.1ACTC1, KIT

GO Terms for genes affiliated with Ovarian Fibrothecoma

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Biological processes related to Ovarian Fibrothecoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.3ACTC1, DES

Sources for Ovarian Fibrothecoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet