MCID: OVR069
MIFTS: 23

Ovarian Germ Cell Tumor

Categories: Rare diseases

Aliases & Classifications for Ovarian Germ Cell Tumor

MalaCards integrated aliases for Ovarian Germ Cell Tumor:

Name: Ovarian Germ Cell Tumor 50 52 69

Classifications:



Summaries for Ovarian Germ Cell Tumor

MalaCards based summary : Ovarian Germ Cell Tumor is related to pediatric ovarian germ cell tumor and germ cells tumors. An important gene associated with Ovarian Germ Cell Tumor is ERVK-6 (Endogenous Retrovirus Group K Member 6, Envelope). The drugs Bleomycin and Carboplatin have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and lung.

Related Diseases for Ovarian Germ Cell Tumor

Diseases related to Ovarian Germ Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
id Related Disease Score Top Affiliating Genes
1 pediatric ovarian germ cell tumor 12.2
2 germ cells tumors 10.7
3 teratoma 10.0
4 meige syndrome 10.0
5 growing teratoma syndrome 10.0
6 pseudo-meigs syndrome 10.0
7 testicular germ cell tumor 9.7
8 cortical blindness 9.7
9 gonadal dysgenesis 9.7
10 teratocarcinoma 9.7
11 embryonal carcinoma 9.7
12 peritonitis 9.7
13 hemangioendothelioma 9.7
14 epithelioid hemangioendothelioma 9.7

Graphical network of the top 20 diseases related to Ovarian Germ Cell Tumor:



Diseases related to Ovarian Germ Cell Tumor

Symptoms & Phenotypes for Ovarian Germ Cell Tumor

Drugs & Therapeutics for Ovarian Germ Cell Tumor

Drugs for Ovarian Germ Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 291)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bleomycin Approved Phase 3,Phase 2 11056-06-7 5360373
2
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
3
Cisplatin Approved Phase 3,Phase 1,Phase 2 15663-27-1 84093 441203 2767
4
Etoposide Approved Phase 3,Phase 1,Phase 2 33419-42-0 36462
5
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
6
Vinblastine Approved Phase 3,Phase 1 865-21-4 13342 241903
7
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
8
Paclitaxel Approved, Vet_approved Phase 3,Phase 1,Phase 2 33069-62-4 36314
9
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
10
Ofloxacin Approved Phase 3 82419-36-1 4583
11
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
12
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
13
Morphine Approved, Investigational Phase 3 57-27-2 5288826
14
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
15
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
16
Caspofungin Approved Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
17
Fluconazole Approved Phase 3 86386-73-4 3365
18
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
19
Palivizumab Approved, Investigational Phase 3 188039-54-5
20
Ribavirin Approved Phase 3 36791-04-5 37542
21
Captopril Approved Phase 3 62571-86-2 44093
22
Cyproheptadine Approved Phase 3 129-03-3 2913
23
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
24
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
25
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
26
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
27
Norgestimate Approved Phase 3 35189-28-7 6540478
28
Dehydroepiandrosterone Approved, Nutraceutical Phase 3 53-43-0 9860744
29 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
30 Alkylating Agents Phase 3,Phase 1,Phase 2
31 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
32 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
33 Antimitotic Agents Phase 3,Phase 1,Phase 2
34 Antineoplastic Agents, Phytogenic Phase 3,Phase 1,Phase 2
35 Etoposide phosphate Phase 3,Phase 1,Phase 2
36 Isophosphamide mustard Phase 3,Phase 1,Phase 2
37 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Early Phase 1
38 Anti-Infective Agents Phase 3,Phase 1,Phase 2
39 Liver Extracts Phase 3,Phase 2,Phase 1
40 Protective Agents Phase 3,Phase 2,Phase 1
41 Antimetabolites Phase 3,Phase 1,Phase 2
42 Antiviral Agents Phase 3,Phase 1,Phase 2
43 Antirheumatic Agents Phase 3,Phase 2,Phase 1
44 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
45 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
46 Albumin-Bound Paclitaxel Phase 3,Phase 1,Phase 2
47 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
48 Cytochrome P-450 Enzyme Inhibitors Phase 3
49 Renal Agents Phase 3
50 Adjuvants, Anesthesia Phase 3

Interventional clinical trials:

(show top 50) (show all 192)

id Name Status NCT ID Phase Drugs
1 Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors Unknown status NCT00274950 Phase 3 carboplatin;cisplatin;etoposide;ifosfamide;vinblastine sulfate
2 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
3 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
4 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
5 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3 sodium thiosulfate
6 E-MOSAIC Electronic Tool to Monitor Symptoms Completed NCT00477919 Phase 3
7 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
8 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
10 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
11 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
12 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
13 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
14 A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families Completed NCT00782145 Phase 3
15 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
16 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3 cisplatin;etoposide
17 Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms Active, not recruiting NCT01376349 Phase 3 prasterone
18 TC or BEP in Treating Patients With Malignant Ovarian Germ Cell Tumors Enrolling by invitation NCT02429687 Phase 3 Paclitaxel;Carboplatin;Bleomycin;Etoposide;Cisplatin
19 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
20 Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant Terminated NCT00324324 Phase 3 moxifloxacin hydrochloride;Placebo
21 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
22 Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Ovarian Cancer Unknown status NCT00003532 Phase 2 antineoplaston A10;antineoplaston AS2-1
23 Squalamine Lactate Plus Carboplatin in Treating Patients With Recurrent or Refractory Stage III or Stage IV Ovarian Cancer Unknown status NCT00021385 Phase 2 carboplatin;squalamine lactate
24 Paclitaxel-Loaded Polymeric Micelle and Carboplatin as First-Line Therapy in Treating Patients With Advanced Ovarian Cancer Unknown status NCT00886717 Phase 1, Phase 2 carboplatin;paclitaxel-loaded polymeric micelle
25 Whole Body Hyperthermia Combined With Chemotherapy in Treating Patients With Metastatic Breast, Ovarian, Endometrial, or Cervical Cancer Unknown status NCT00003135 Phase 2 fluorouracil;pegylated liposomal doxorubicin hydrochloride
26 Nutritional Supplements in Improving Quality of Life During First-Line Chemotherapy in Patients With Metastatic Gynecological Cancer Unknown status NCT00905658 Phase 2
27 Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation Unknown status NCT00036712 Phase 2
28 Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin Completed NCT00002559 Phase 1, Phase 2 cisplatin;ifosfamide;paclitaxel
29 Paclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell Tumors Completed NCT00003518 Phase 2 gemcitabine hydrochloride;paclitaxel
30 Temozolomide in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to Cisplatin Completed NCT00006043 Phase 2 temozolomide
31 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors Completed NCT00002558 Phase 1, Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
32 Combination Chemotherapy Followed by Bone Marrow or Stem Cell Transplantation in Treating Patients With Relapsed or Refractory Germ Cell Tumors Completed NCT00002508 Phase 1, Phase 2 carboplatin;etoposide
33 Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors Completed NCT00002489 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;leucovorin calcium;methotrexate;vincristine sulfate
34 Docetaxel in Treating Patients With Recurrent or Refractory Germ Cell Cancer Completed NCT00002903 Phase 2 docetaxel
35 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 paclitaxel;carboplatin;ifosfamide
36 Doxorubicin and Carboplatin in Treating Patients With Recurrent Ovarian Cancer Completed NCT00562185 Phase 1, Phase 2 carboplatin;doxorubicin hydrochloride
37 Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Completed NCT00957905 Phase 2 Alvocidib Hydrochloride;Fluorouracil;Leucovorin Calcium;Oxaliplatin
38 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
39 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
40 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
41 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2 carboplatin;ifosfamide;paclitaxel
42 Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors Completed NCT00003811 Phase 2 amifostine trihydrate;cisplatin;etoposide
43 Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies Completed NCT01079832 Phase 2
44 Carboplatin, Etoposide, Cyclophosphamide, and Autologous Bone Marrow Transplantation in Patients With Relapsed or Refractory Cancer Completed NCT00002943 Phase 2 carboplatin;cyclophosphamide;etoposide
45 Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer Completed NCT00664781 Phase 2 rucaparib (CO-338; formally AG-014699 or PF-01367338)
46 High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors Completed NCT00003173 Phase 2 thiotepa
47 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
48 High-dose ICE With Amifostine Completed NCT00003657 Phase 2 Amifostine;Carboplatin;Etoposide;Ifosfamide
49 Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer Completed NCT00237627 Phase 1, Phase 2 PS-341;Doxil;Velcade
50 Chemotherapy in Treating Patients With Solid Tumors Completed NCT00003103 Phase 1, Phase 2 docetaxel

Search NIH Clinical Center for Ovarian Germ Cell Tumor

Genetic Tests for Ovarian Germ Cell Tumor

Anatomical Context for Ovarian Germ Cell Tumor

MalaCards organs/tissues related to Ovarian Germ Cell Tumor:

39
Bone, Bone Marrow, Lung, Colon, T Cells, Breast, Liver

Publications for Ovarian Germ Cell Tumor

Articles related to Ovarian Germ Cell Tumor:

(show top 50) (show all 74)
id Title Authors Year
1
Is Omentectomy Mandatory Among Early Stage (I, II) Malignant Ovarian Germ Cell Tumor Patients? A Retrospective Study of 223 Cases. ( 28520571 )
2017
2
Laparoscopic Treatment of Mixed Malignant Ovarian Germ Cell Tumor in a 16-Year-Old Female Adolescent. ( 27262834 )
2016
3
Outcomes of pediatric and adolescent girls with malignant ovarian germ cell tumors. ( 25842162 )
2015
4
Outcomes of Ovarian Germ Cell Tumors: Ten Years of Experience at the Brazilian National Cancer Institute. ( 25790041 )
2015
5
8-year analysis of the prevalence of lymph nodes metastasis, oncologic and pregnancy outcomes in apparent early-stage malignant ovarian germ cell tumors. ( 25743840 )
2015
6
Fertility and gonadal function after adjuvant therapy in women diagnosed with a malignant ovarian germ cell tumor (MOGCT) during the "cisplatin era". ( 25511159 )
2015
7
Incidence of malignant ovarian germ cell tumors (MOGCTs) in Saudi Arabia. ( 24412326 )
2014
8
Surveillance After Initial Surgery for Pediatric and Adolescent Girls With Stage I Ovarian Germ Cell Tumors: Report From the Children's Oncology Group. ( 24395845 )
2014
9
Malignant ovarian germ cell tumor - role of surgical staging and gonadal dysgenesis. ( 24836278 )
2014
10
Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma. ( 25518772 )
2014
11
Gynecologic Cancer Intergroup (GCIG) Consensus Review for Ovarian Germ Cell Tumors. ( 25341580 )
2014
12
Imaging features of growing teratoma syndrome following a malignant ovarian germ cell tumor. ( 24681864 )
2014
13
Long-term oncological and reproductive outcomes of fertility-sparing cytoreductive surgery in females aged 25 years and younger with malignant ovarian germ cell tumors. ( 24320102 )
2013
14
Malignant ovarian germ cell tumors: presentation, survival and second cancer in a population based Norwegian cohort (1953-2009). ( 24001518 )
2013
15
Updates in the management of ovarian germ cell tumors. ( 23714505 )
2013
16
Usefulness of intraoperative imprint cytology in ovarian germ cell tumors. ( 23406948 )
2013
17
Systemic thromboembolism after anti-cancer chemotherapy in a woman with ovarian germ cell tumor. ( 23148694 )
2013
18
Pelvic pain, free fluid in pelvis, and human chorionic gonadotropin serum elevation: recurrence of malignant ovarian germ-cell tumor or early pregnancy? ( 24475592 )
2013
19
Bleomycin cardiotoxicity during chemotherapy for an ovarian germ cell tumor. ( 24376332 )
2013
20
Clinical and radiologic signs of relapsed ovarian germ cell tumor: tissue is the issue. ( 24222875 )
2013
21
Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis. ( 23575763 )
2013
22
The significance of comprehensive staging surgery in malignant ovarian germ cell tumors. ( 24007946 )
2013
23
Minilaparotomy a good option in specific cases: a case report of bilateral ovarian germ cell tumor. ( 22567526 )
2012
24
Treatment of malignant ovarian germ cell tumors and preservation of fertility. ( 23185794 )
2012
25
Molecular genetic analysis of bilateral ovarian germ cell tumors. ( 23143763 )
2012
26
Ovarian germ cell tumors with rhabdomyosarcomatous components and later development of growing teratoma syndrome: a case report. ( 22248255 )
2012
27
Outcome and risk factors for recurrence in malignant ovarian germ cell tumors: a MITO-9 retrospective study. ( 21795985 )
2011
28
Malignant mixed ovarian germ cell tumor with embryonal component. ( 20869284 )
2011
29
Survival and reproductive outcomes in women treated for malignant ovarian germ cell tumors. ( 21256579 )
2011
30
Management of malignant ovarian germ cell tumors. ( 22018453 )
2011
31
Prognostic impact of laterality in malignant ovarian germ cell tumors. ( 21475076 )
2011
32
Uncommon vascular tumor of the ovary. Primary ovarian epithelioid hemangioendothelioma or vascular sarcomatous transformation in ovarian germ cell tumor? ( 21822906 )
2011
33
Residual tumor after the salvage surgery is the major risk factors for primary treatment failure in malignant ovarian germ cell tumors: a retrospective study of single institution. ( 21988930 )
2011
34
Ovarian germ cell tumors in children: a 20-year retrospective study in a single institution. ( 21797119 )
2011
35
Karyotype result prior to surgery in patients with suspected ovarian germ cell tumors. ( 21594985 )
2011
36
Bulletin board. Study suggests that following surgery, watchful waiting may be a safe option for girls with early-stage ovarian germ cell tumors. ( 21188885 )
2010
37
Ovarian germ cell tumors in children. Management, survival and ovarian prognosis. A report of 75 cases. ( 20638529 )
2010
38
Clinical presentation and outcome of pediatric ovarian germ cell tumor: a study of 40 patients. ( 20168245 )
2010
39
Malignant ovarian germ cell tumors: clinico-pathological presentation and survival outcomes. ( 19961281 )
2010
40
Young girls with malignant ovarian germ cell tumors can undergo normal menarche and menstruation after fertility-preserving surgery and adjuvant chemotherapy. ( 19878051 )
2010
41
Malignant ovarian germ cell tumors: a single-institution experience. ( 19307952 )
2009
42
Embryonic stem cell transcription factors and D2-40 (podoplanin) as diagnostic immunohistochemical markers in ovarian germ cell tumors. ( 19483629 )
2009
43
A mini-review of familial ovarian germ cell tumors: an additional manifestation of the familial testicular germ cell tumor syndrome. ( 19679044 )
2009
44
Chronic physical effects and health care utilization in long-term ovarian germ cell tumor survivors: a Gynecologic Oncology Group study. ( 19636015 )
2009
45
FDG uptake in parahepatic brown fat mimics peritoneal carcinomatosis in a malignant ovarian germ cell tumor: resolution with temperature control. ( 18936621 )
2008
46
Tissue AP-2gamma and Oct-3/4, and serum CA 125 as diagnostic and prognostic markers of malignant ovarian germ cell tumors. ( 18497549 )
2008
47
The influence of conservative surgical practices for malignant ovarian germ cell tumors. ( 18563734 )
2008
48
Case-control comparison of quality of life in long-term ovarian germ cell tumor survivors: a gynecologic oncology group study. ( 19042263 )
2008
49
Mixed ovarian germ cell tumor in a BRCA2 mutation carrier. ( 17413983 )
2007
50
[Survivin expression in ovarian germ cell tumors]. ( 17441339 )
2007

Variations for Ovarian Germ Cell Tumor

Expression for Ovarian Germ Cell Tumor

Search GEO for disease gene expression data for Ovarian Germ Cell Tumor.

Pathways for Ovarian Germ Cell Tumor

GO Terms for Ovarian Germ Cell Tumor

Sources for Ovarian Germ Cell Tumor

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