MCID: OVR071
MIFTS: 9

Ovarian Insufficiency, Familial

Categories: Rare diseases, Genetic diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Insufficiency, Familial

MalaCards integrated aliases for Ovarian Insufficiency, Familial:

Name: Ovarian Insufficiency, Familial 38 50

Classifications:



Summaries for Ovarian Insufficiency, Familial

MalaCards based summary : Ovarian Insufficiency, Familial is related to fmr1-related primary ovarian insufficiency. The drugs Anastrozole and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include Ovary.

Related Diseases for Ovarian Insufficiency, Familial

Diseases in the Ovarian Disease family:

Ovarian Insufficiency, Familial Fmr1-Related Primary Ovarian Insufficiency
Ovarian Insufficiency Due to Fsh Resistance

Diseases related to Ovarian Insufficiency, Familial via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 fmr1-related primary ovarian insufficiency 10.9

Symptoms & Phenotypes for Ovarian Insufficiency, Familial

Drugs & Therapeutics for Ovarian Insufficiency, Familial

Drugs for Ovarian Insufficiency, Familial (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Anastrozole Approved, Investigational Phase 2 120511-73-1 2187
2 Hormone Antagonists Phase 2
3 Hormones Phase 2
4 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
5 Antineoplastic Agents, Hormonal Phase 2
6 Aromatase Inhibitors Phase 2
7 Estrogen Antagonists Phase 2
8 Estrogens Phase 2
9 Steroid Synthesis Inhibitors Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Aromatase Inhibitors in Premenopausal Breast Cancer Patients With Chemotherapy-Induced Ovarian Failure Terminated NCT00555477 Phase 2 anastrozole
2 Inovium Ovarian Rejuvenation Trials Recruiting NCT03178695 Phase 1
3 Genetic Analysis of Familial Cases of Premature Ovarian Failure Completed NCT01177891
4 Social Cognition and Turner Syndrome Completed NCT01687842
5 Evaluation of Overall Compliance and Duration of Zomacton® Treatment With the Zomajet® Needle-free Device Completed NCT01306357 Somatropin
6 Turner Syndrome Research Network Registry Recruiting NCT03185702
7 Expanded Noninvasive Genomic Medical Assessment: The Enigma Study Recruiting NCT02787486
8 The Natural History of Reproductive and Overall Health in Girls and Women With a Pre-Mutation in the FMR1 Gene; Creation of a Patient Registry Terminated NCT01187524

Search NIH Clinical Center for Ovarian Insufficiency, Familial

Genetic Tests for Ovarian Insufficiency, Familial

Anatomical Context for Ovarian Insufficiency, Familial

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Ovarian Insufficiency, Familial:
id Tissue Anatomical CompartmentCell Relevance
1 Ovary Secondary Follicle Affected by disease

Publications for Ovarian Insufficiency, Familial

Variations for Ovarian Insufficiency, Familial

Expression for Ovarian Insufficiency, Familial

Search GEO for disease gene expression data for Ovarian Insufficiency, Familial.

Pathways for Ovarian Insufficiency, Familial

GO Terms for Ovarian Insufficiency, Familial

Sources for Ovarian Insufficiency, Familial

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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