MCID: OVR096
MIFTS: 20

Overlap Myositis

Categories: Neuronal diseases, Bone diseases, Rare diseases

Aliases & Classifications for Overlap Myositis

MalaCards integrated aliases for Overlap Myositis:

Name: Overlap Myositis 55
Adult-Onset Overlap Myositis 55
Non-Specific Myositis 55
Myositis 69

Characteristics:

Orphanet epidemiological data:

55
overlap myositis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:



External Ids:

Orphanet 55 ORPHA206572

Summaries for Overlap Myositis

MalaCards based summary : Overlap Myositis, also known as adult-onset overlap myositis, is related to juvenile overlap myositis and myositis, and has symptoms including myalgia, muscle weakness and torticollis. The drugs Abatacept and Immunosuppressive Agents have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Overlap Myositis

Diseases in the Overlap Myositis family:

Juvenile Overlap Myositis

Diseases related to Overlap Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 juvenile overlap myositis 12.3
2 myositis 10.0
3 dermatomyositis 9.8
4 polymyositis 9.8
5 tetrasomy 9p 9.6
6 scleroderma, familial progressive 9.6

Graphical network of the top 20 diseases related to Overlap Myositis:



Diseases related to Overlap Myositis

Symptoms & Phenotypes for Overlap Myositis

UMLS symptoms related to Overlap Myositis:


myalgia, muscle weakness, torticollis, sciatica, myoclonus, muscle spasticity, muscle rigidity, muscle cramp, back pain

Drugs & Therapeutics for Overlap Myositis

Drugs for Overlap Myositis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Abatacept Approved Phase 3 332348-12-6 10237
2 Immunosuppressive Agents Phase 3
3 Antirheumatic Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy Recruiting NCT02971683 Phase 3 Abatacept subcutaneous;Placebo

Search NIH Clinical Center for Overlap Myositis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Overlap Myositis

Anatomical Context for Overlap Myositis

MalaCards organs/tissues related to Overlap Myositis:

38
Bone

Publications for Overlap Myositis

Articles related to Overlap Myositis:

# Title Authors Year
1
Mosaic Tetrasomy 9p: A Mendelian Condition Associated With Pediatric-Onset Overlap Myositis. ( 26216333 )
2015
2
Redefining dermatomyositis: a description of new diagnostic criteria that differentiate pure dermatomyositis from overlap myositis with dermatomyositis features. ( 25500701 )
2014
3
Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku. ( 22453528 )
2013
4
Cardiac involvement in juvenile overlap-myositis detected by cardiac magnetic resonance imaging. ( 20971516 )
2011
5
Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis. ( 21376512 )
2011
6
Myositis-specific and myositis-associated antibodies in overlap myositis in comparison to primary dermatopolymyositis: Relevance for clinical classification: retrospective study of 169 patients. ( 20188618 )
2010

Variations for Overlap Myositis

Expression for Overlap Myositis

Search GEO for disease gene expression data for Overlap Myositis.

Pathways for Overlap Myositis

GO Terms for Overlap Myositis

Sources for Overlap Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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