MCID: OXY002
MIFTS: 31

Oxyphilic Adenoma malady

Cancer diseases category

Summaries for Oxyphilic Adenoma

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Wikipedia:63 An oncocytoma is a tumor made up of oncocytes, epithelial cells characterized by an excessive amount of... more...

MalaCards based summary: Oxyphilic Adenoma, also known as oncocytoma, is related to renal oncocytoma and renal cell carcinoma, and has symptoms including mitochondrial inheritance, abnormality of metabolism/homeostasis and neoplasm. An important gene associated with Oxyphilic Adenoma is FLCN (folliculin). The compounds mucicarmine and b 723 have been mentioned in the context of this disorder. Affiliated tissues include thyroid and salivary gland.

Aliases & Classifications for Oxyphilic Adenoma

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 38NCIt, 33MeSH, 55SNOMED-CT
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Oxyphilic Adenoma, Aliases & Descriptions:

Name: Oxyphilic Adenoma 9 11 60
Oncocytoma 9 43
Follicular Adenoma, Oxyphilic Cell 9
 
Hurthle Cell Tumor 60
Oncocytic Neoplasm 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology9 DOID:5389
NCIt38 C3759
SNOMED-CT55 89439007
MeSH33 D018249

Related Diseases for Oxyphilic Adenoma

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Diseases related to Oxyphilic Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 71)
idRelated DiseaseScoreTop Affiliating Genes
1renal oncocytoma30.6KRT7, S100A1, PVALB, PRCC, FLCN, CLDN8
2renal cell carcinoma30.6CDH16, KRT7, CA9, PRCC, FLCN, TFE3
3papillary adenoma30.4PRCC
4papillary carcinoma30.2S100A1, KRT7
5sarcoma29.9CA9, TFE3, S100A1
6renal clear cell carcinoma29.0CA9, CDH16, KRT7, S100A1, CLDN7, PVALB
7chromophobe renal cell carcinoma10.8
8adenoma10.6
9angiomyolipoma10.3
10familial renal oncocytoma10.3
11pituicytoma10.2
12nasopharyngitis10.2
13thyroiditis10.2
14nephrogenic adenoma10.2S100A1, KRT7
15malignant mixed mullerian tumor10.2S100A1, KRT7
16pheochromocytoma10.2
17tuberous sclerosis10.2
18renal adenoma10.2
19clear cell renal cell carcinoma10.2
20aneurysm10.2
21alveolar soft-part sarcoma10.2PRCC, TFE3
22chordoma10.2S100A1, KRT7
23abrikosov's tumor10.1KRT7, S100A1
24mucoepidermoid carcinoma10.1S100A1, KRT7
25salivary gland adenoid cystic carcinoma10.1S100A1, KRT7
26kidney cancer10.1FLCN, CA9
27b-cell lymphomas10.1
28glomerulonephritis10.1
29eosinophilic variant of chromophobe renal cell carcinoma10.1
30granular cell tumor10.1
31chromophobe adenoma10.1
32nephrotic syndrome10.1
33prostatitis10.1
34horseshoe kidney10.1
35mesothelioma, somatic10.1KRT7, S100A1
36mesothelioma10.0KRT7, S100A1
37leiomyoma10.0FLCN, S100A1
38hepatocellular carcinoma9.9
39osteoporosis9.9
40lymphangioleiomyomatosis9.9
41neurofibromatosis, type 19.9
42diffuse large b-cell lymphoma9.9
43myoepithelioma9.9
44perinephritis9.9
45renal fibrosis9.9
46neurofibromatosis9.9
47thyroid hurthle cell adenoma9.9
48chronic dacryocystitis9.9
49bullous pemphigoid9.9
50acidophil adenoma9.9

Graphical network of the top 20 diseases related to Oxyphilic Adenoma:



Diseases related to oxyphilic adenoma

Symptoms for Oxyphilic Adenoma

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HPO human phenotypes related to Oxyphilic Adenoma:

id Description Frequency HPO Source Accession
1 mitochondrial inheritance HP:0001427
2 abnormality of metabolism/homeostasis HP:0001939
3 neoplasm HP:0002664

Drugs & Therapeutics for Oxyphilic Adenoma

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Drug clinical trials:

Search ClinicalTrials for Oxyphilic Adenoma

Search NIH Clinical Center for Oxyphilic Adenoma

Genetic Tests for Oxyphilic Adenoma

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Anatomical Context for Oxyphilic Adenoma

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MalaCards organs/tissues related to Oxyphilic Adenoma:

31
Thyroid, Salivary gland

Animal Models for Oxyphilic Adenoma or affiliated genes

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Publications for Oxyphilic Adenoma

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Articles related to Oxyphilic Adenoma:

idTitleAuthorsYear
1
Ultrastructural study of glycogen-rich oxyphilic adenoma of the nasopharyngeal minor salivary gland. (3927580)
1985
2
Oxyphilic adenoma of the parotid gland. Identification with 99mTc-pertechnetate. (674638)
1978
3
The angiographic appearance of benign renal oxyphilic adenoma. (973655)
1976
4
Oxyphilic adenoma of the human thyroid. A morphological and biochemical study. (4118915)
1973
5
Oxyphilic adenoma of the larynx. (5027594)
1972
6
Onkocytoma (oxyphilic adenoma) of the caruncle. (6036309)
1967
7
OXYPHILIC ADENOMA (ONCOCYTOMA) OF THE LARYNX; PRESENTATION OF A CASE. (14310177)
1965
8
Oxyphilic adenoma of the parotid gland; report of a case. (13172681)
1954

Variations for Oxyphilic Adenoma

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Expression for genes affiliated with Oxyphilic Adenoma

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Search GEO for disease gene expression data for Oxyphilic Adenoma.

Pathways for genes affiliated with Oxyphilic Adenoma

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Compounds for genes affiliated with Oxyphilic Adenoma

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Sources:
43Novoseek, 24HMDB
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Compounds related to Oxyphilic Adenoma according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1mucicarmine439.6S100A1, KRT7
2b 723439.5KRT7, S100A1
3hematoxylin439.2KRT7, S100A1
4iron43 249.7KRT7, S100A1, PVALB
5paraffin438.4KRT7, S100A1, CA9, PVALB
6estrogen438.2PVALB, CA9, S100A1, KRT7

GO Terms for genes affiliated with Oxyphilic Adenoma

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Biological processes related to Oxyphilic Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell adhesionGO:00457859.8FLCN, TFE3
2calcium-independent cell-cell adhesionGO:00163389.6CLDN7, CLDN8

Molecular functions related to Oxyphilic Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:00051989.4KRT7, CLDN7, CLDN8

Products for genes affiliated with Oxyphilic Adenoma

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  • Antibodies
  • Proteins
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  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Oxyphilic Adenoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet