MCID: OXY002
MIFTS: 34

Oxyphilic Adenoma malady

Cancer diseases category
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Summaries for Oxyphilic Adenoma

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MalaCards based summary: Oxyphilic Adenoma, also known as oncocytoma, is related to renal oncocytoma and papillary adenoma, and has symptoms including An important gene associated with Oxyphilic Adenoma is FLCN (folliculin). The compounds mucicarmine and b 723 have been mentioned in the context of this disorder. Affiliated tissues include thyroid and salivary gland.

Aliases & Classifications for Oxyphilic Adenoma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 39NCIt, 57SNOMED-CT, 34MeSH
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Oxyphilic Adenoma, Aliases & Descriptions:

Name: Oxyphilic Adenoma 8 10
Oncocytoma 8 44
 
Follicular Adenoma, Oxyphilic Cell 8
Hurthle Cell Tumor 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:5389
NCIt39 C3759
SNOMED-CT57 89439007
MeSH34 D018249

Related Diseases for Oxyphilic Adenoma

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Diseases related to Oxyphilic Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1renal oncocytoma30.6KRT7, S100A1, PVALB, PRCC, FLCN, CLDN8
2papillary adenoma30.4PRCC
3papillary carcinoma30.2S100A1, KRT7
4sarcoma29.9CA9, TFE3, S100A1
5renal cell carcinoma10.9
6chromophobe renal cell carcinoma10.8
7adenoma10.6
8papillary renal cell carcinoma10.3
9angiomyolipoma10.3
10familial renal oncocytoma10.2
11nephrogenic adenoma10.2S100A1, KRT7
12nasopharyngitis10.2
13thyroiditis10.2
14malignant mixed mullerian tumor10.2S100A1, KRT7
15alveolar soft part sarcoma10.2PRCC, TFE3
16chordoma10.2S100A1, KRT7
17tuberous sclerosis10.2
18renal adenoma10.2
19pheochromocytoma10.2
20aneurysm10.2
21pituicytoma10.2
22abrikosov's tumor10.2KRT7, S100A1
23mucoepidermoid carcinoma10.1S100A1, KRT7
24salivary gland adenoid cystic carcinoma10.1S100A1, KRT7
25kidney rhabdoid cancer10.1FLCN, CA9
26b-cell lymphomas10.1
27glomerulonephritis10.1
28hypertension10.1
29granular cell tumor10.1
30eosinophilic variant of chromophobe renal cell carcinoma10.1
31thyroid hurthle cell adenoma10.1
32chromophobe adenoma10.1
33nephrotic syndrome10.1
34clear cell renal cell carcinoma10.1
35horseshoe kidney10.1
36malignant mesothelioma10.0KRT7, S100A1
37leiomyoma10.0FLCN, S100A1
38diffuse large b-cell lymphoma9.9
39hepatocellular carcinoma9.9
40hodgkin's lymphoma9.9
41osteoporosis9.9
42myoepithelioma9.9
43perinephritis9.9
44crescentic glomerulonephritis9.9
45panhypopituitarism9.9
46renal fibrosis9.9
47chronic dacryocystitis9.9
48acidophil adenoma9.9
49collecting duct carcinoma9.9
50cushing's syndrome9.9

Graphical network of the top 20 diseases related to Oxyphilic Adenoma:



Diseases related to oxyphilic adenoma

Symptoms for Oxyphilic Adenoma

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HPO human phenotypes related to Oxyphilic Adenoma:

id Description Frequency HPO Source Accession
1 mitochondrial inheritance HP:0001427
2 abnormality of metabolism/homeostasis HP:0001939
3 neoplasm HP:0002664

Drugs & Therapeutics for Oxyphilic Adenoma

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Drug clinical trials:

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Genetic Tests for Oxyphilic Adenoma

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Anatomical Context for Oxyphilic Adenoma

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MalaCards organs/tissues related to Oxyphilic Adenoma:

32
Thyroid, Salivary gland

Animal Models for Oxyphilic Adenoma or affiliated genes

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Publications for Oxyphilic Adenoma

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Articles related to Oxyphilic Adenoma:

idTitleAuthorsYear
1
Ultrastructural study of glycogen-rich oxyphilic adenoma of the nasopharyngeal minor salivary gland. (3927580)
1985
2
Oxyphilic adenoma of the parotid gland. Identification with 99mTc-pertechnetate. (674638)
1978
3
The angiographic appearance of benign renal oxyphilic adenoma. (973655)
1976
4
Oxyphilic adenoma of the human thyroid. A morphological and biochemical study. (4118915)
1973
5
Oxyphilic adenoma of the larynx. (5027594)
1972
6
Onkocytoma (oxyphilic adenoma) of the caruncle. (6036309)
1967
7
OXYPHILIC ADENOMA (ONCOCYTOMA) OF THE LARYNX; PRESENTATION OF A CASE. (14310177)
1965
8
Oxyphilic adenoma of the parotid gland; report of a case. (13172681)
1954

Variations for Oxyphilic Adenoma

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Expression for genes affiliated with Oxyphilic Adenoma

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Expression patterns in normal tissues for genes affiliated with Oxyphilic Adenoma

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Pathways for genes affiliated with Oxyphilic Adenoma

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Compounds for genes affiliated with Oxyphilic Adenoma

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Sources:
44Novoseek, 24HMDB
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Compounds related to Oxyphilic Adenoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1mucicarmine449.6S100A1, KRT7
2b 723449.5S100A1, KRT7
3hematoxylin449.2KRT7, S100A1
4iron44 249.7S100A1, PVALB, KRT7
5paraffin448.4KRT7, S100A1, CA9, PVALB
6estrogen448.2KRT7, PVALB, CA9, S100A1

GO Terms for genes affiliated with Oxyphilic Adenoma

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Biological processes related to Oxyphilic Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell adhesionGO:0457859.8FLCN, TFE3
2calcium-independent cell-cell adhesionGO:0163389.6CLDN7, CLDN8

Molecular functions related to Oxyphilic Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:0051989.4KRT7, CLDN7, CLDN8

Products for genes affiliated with Oxyphilic Adenoma

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  • Antibodies
  • Proteins
  • Lysates

Sources for Oxyphilic Adenoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet