MCID: OXY002
MIFTS: 36

Oxyphilic Adenoma malady

Cancer diseases category

Summaries for Oxyphilic Adenoma

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Oxyphilic Adenoma, also known as oncocytoma, is related to renal oncocytoma and adenoma. An important gene associated with Oxyphilic Adenoma is FLCN (folliculin). The compounds 2-methoxyethanol and toluidine have been mentioned in the context of this disorder. Affiliated tissues include bone, thyroid and salivary gland.

Aliases & Classifications for Oxyphilic Adenoma

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 39NCIt, 34MeSH, 56SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

oxyphilic adenoma 8 10
oncocytoma 8 44
follicular adenoma, oxyphilic cell 8
hurthle cell tumor 60


External Ids:

Disease Ontology8 DOID:5389
NCIt39 C3759
SNOMED-CT56 89439007
MeSH34 D018249

Related Diseases for Oxyphilic Adenoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Oxyphilic Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1renal oncocytoma31.7SYNGR3, PRCC, CDH16, CLDN8, KRT7, FLCN
2adenoma30.8KRT7, S100A1
3angiomyolipoma30.3VIM, S100A1
4renal clear cell carcinoma30.2KRT7, VIM, CLDN7, CA9, S100A1, CDH16
5papillary adenoma30.0PRCC
6myoepithelioma29.8S100A1, VIM
7sarcoma29.8VIM, CA9, S100A1, TFE3
8renal cell carcinoma10.8
9papillary carcinoma10.3
10papillary renal cell carcinoma10.3
11eosinophilic variant of chromophobe renal cell carcinoma10.2
12familial renal oncocytoma10.2
13pituitary adenoma10.2
14thyroid hurthle cell carcinoma10.2
15nasopharyngitis10.1
16renal adenoma10.1
17thyroiditis10.1
18tuberous sclerosis10.1
19pheochromocytoma10.1
20small cell carcinoma10.0
21granular cell tumor10.0
22chromophobe adenoma10.0
23glomerulonephritis10.0
24hypertension10.0
25kidney angiomyolipoma10.0
26nephrotic syndrome10.0
27prostatitis10.0
28renal hypertension10.0
29perivascular epithelioid cell tumor10.0TFE3
30lipoma10.0S100A1
31paraganglioma10.0S100A1
32renal cell carcinoma, papillary, 110.0TFE3, PRCC
33cystadenoma10.0KRT7
34thymus cancer10.0KRT7
35synovial sarcoma10.0KRT7
36syringoma10.0S100A1
37metanephric adenoma10.0KRT7
38ependymoma10.0VIM
39mixed cell type cancer10.0KRT7
40alveolar soft part sarcoma10.0VIM, TFE3
41teratoma10.0KRT7
42adenomatoid tumor10.0VIM
43fibromatosis10.0VIM, S100A1
44nephrogenic adenoma10.0S100A1, KRT7
45pseudomyxoma peritonei10.0KRT7
46pneumothorax10.0FNIP1, FLCN, FNIP2
47endometrial carcinoma10.0CA9, KRT7
48fibrosarcoma10.0CA9, VIM
49leiomyoma10.0FLCN, S100A1, VIM
50spindle cell sarcoma10.0KRT7, VIM

Graphical network of the top 20 diseases related to Oxyphilic Adenoma:



Diseases related to oxyphilic adenoma

Clinical Features for Oxyphilic Adenoma

About this section

Drugs & Therapeutics for Oxyphilic Adenoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Oxyphilic Adenoma

Drug clinical trials:

Search ClinicalTrials for Oxyphilic Adenoma

Search NIH Clinical Center for Oxyphilic Adenoma

Search CenterWatch for Oxyphilic Adenoma

Genetic Tests for Oxyphilic Adenoma

About this section

Anatomical Context for Oxyphilic Adenoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Oxyphilic Adenoma:

32
Bone, Thyroid, Salivary gland

Animal Models for Oxyphilic Adenoma or affiliated genes

About this section

Publications for Oxyphilic Adenoma

About this section
Sources:
50PubMed
See all sources

Articles related to Oxyphilic Adenoma:

(show all 16)
idTitleAuthorsYear
1
Parathyroid carcinoma and oxyphil parathyroid adenoma: an uncommon case of misinterpretation in clinical practice. (23268928)
2013
2
Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level. (18291038)
2008
3
Preoperative localization of parathyroid adenomas with technetium-99m methoxyisobutylisonitrile imaging: relationship with P-glycoprotein expression, oxyphilic cell content, and tumoral tissue volume. (17257073)
2006
4
Oxyphilic cell adenoma of parathyroid resulting in primary hyperparathyroidism and osteitis fibrosa cystica--a case report. (17001919)
2006
5
Oxyphil parathyroid adenoma: a malignant presentation of a benign disease. (15579742)
2004
6
A peculiar Factor VIII-related antigen staining of an oxyphilic cell nodule within an intrathyroidal parathyroid adenoma. (10338086)
1999
7
Oxyphilic parathyroid adenoma and lithium therapy. (9759787)
1998
8
Oxyphil parathyroid adenoma associated with primary hyperparathyroidism and marked post-operative hungry bone syndrome. (8842760)
1996
9
Ultrastructural study of glycogen-rich oxyphilic adenoma of the nasopharyngeal minor salivary gland. (3927580)
1985
10
Oxyphilic adenoma of the parotid gland. Identification with 99mTc-pertechnetate. (674638)
1978
11
The angiographic appearance of benign renal oxyphilic adenoma. (973655)
1976
12
Oxyphilic adenoma of the human thyroid. A morphological and biochemical study. (4118915)
1973
13
Oxyphilic adenoma of the larynx. (5027594)
1972
14
Onkocytoma (oxyphilic adenoma) of the caruncle. (6036309)
1967
15
OXYPHILIC ADENOMA (ONCOCYTOMA) OF THE LARYNX; PRESENTATION OF A CASE. (14310177)
1965
16
Oxyphilic adenoma of the parotid gland; report of a case. (13172681)
1954

Genetic Variations for Oxyphilic Adenoma

About this section

Expression for genes affiliated with Oxyphilic Adenoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Oxyphilic Adenoma

Search GEO for disease gene expression data for Oxyphilic Adenoma.

Pathways for genes affiliated with Oxyphilic Adenoma

About this section

Compounds for genes affiliated with Oxyphilic Adenoma

About this section
Sources:
44Novoseek
See all sources

Compounds related to Oxyphilic Adenoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
12-methoxyethanol449.8VIM, S100A1
2toluidine449.6S100A1, VIM
3reticulin449.4KRT7, VIM
4mucicarmine449.3KRT7, S100A1, VIM
5b 723449.2KRT7, S100A1, VIM
6hematoxylin449.1KRT7, S100A1, VIM
7paraffin448.5VIM, PVALB, CA9, S100A1, KRT7

GO Terms for genes affiliated with Oxyphilic Adenoma

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Oxyphilic Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of pro-B cell differentiationGO:200097310.1FNIP1, FLCN
2calcium-independent cell-cell adhesionGO:01633810.0CLDN7, CLDN8
3TOR signaling cascadeGO:03192910.0FNIP1, FLCN
4negative regulation of TOR signaling cascadeGO:0320079.8FNIP1, FLCN
5regulation of protein phosphorylationGO:0019329.7FNIP1, FNIP2, FLCN
6negative regulation of transcription from RNA polymerase II promoterGO:0001228.7S100A1, UBE2D3, FLCN, FNIP2, FNIP1

Products for genes affiliated with Oxyphilic Adenoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Oxyphilic Adenoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet