Aliases & Classifications for Oxyphilic Adenoma

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Aliases & Descriptions for Oxyphilic Adenoma:

Name: Oxyphilic Adenoma 10 12 65
Oncocytoma 10 47
Follicular Adenoma, Oxyphilic Cell 10
 
Hurthle Cell Tumor 65
Adenoma, Oxyphilic 36
Oncocytic Neoplasm 65

Characteristics:

HPO:

61


Classifications:



External Ids:

Disease Ontology10 DOID:5389
MeSH36 D018249
SNOMED-CT59 89439007
NCIt42 C3759
UMLS65 C1510502, C0949541, C1378050

Summaries for Oxyphilic Adenoma

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Wikipedia:68 An oncocytoma is a tumor made up of oncocytes, epithelial cells characterized by an excessive amount of... more...

MalaCards based summary: Oxyphilic Adenoma, also known as oncocytoma, is related to renal cell carcinoma and renal oncocytoma, and has symptoms including neoplasmand abnormality of metabolism/homeostasis. An important gene associated with Oxyphilic Adenoma is MT-ND6 (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 6), and among its related pathways is Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include breast, kidney and thyroid, and related mouse phenotypes are tumorigenesis and cellular.

Related Diseases for Oxyphilic Adenoma

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Diseases related to Oxyphilic Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 127)
idRelated DiseaseScoreTop Affiliating Genes
1renal cell carcinoma30.3AMACR, FH, FLCN, KIT, MME, PAX2
2renal oncocytoma12.4
3familial renal oncocytoma12.1
4thyroid hurthle cell adenoma10.9
5nephrogenic adenofibroma10.7AMACR, PAX2
6breast mucinous carcinoma10.7MME, PAX2
7eccrine acrospiroma10.7KIT, MME
8methotrexate-associated lymphoproliferation10.7MME, PAX2
9mediastinum seminoma10.7FH, FLCN
10pancreatic signet ring cell adenocarcinoma10.7MME, SYP
11gangliocytoma10.7KIT, SYP
12hyperaldosteronism10.7FH, FLCN
13bartholin's gland small cell carcinoma10.6KIT, SYP
14mediastinal mesenchymal tumor10.6KIT, SYP
15caroli disease10.6KIT, SYP
16small intestine leiomyoma10.6MME, SYP
17intravascular angioleiomyoma10.6KIT, SYP
18intestinal pseudo-obstruction10.6KIT, SYP
19meninges hemangiopericytoma10.6MME, SYP
20spina bifida occulta10.6KIT, SYP
21prostatic urethra urothelial carcinoma10.5FH, FLCN
22linear nevus sebaceus syndrome10.5LGALS3, PAX2
23mucinous tubular and spindle renal cell carcinoma10.5FLCN, KIT, MME
24chromophobe renal cell carcinoma10.5
25small cell neuroendocrine carcinoma10.5KIT, SYP
26renal tubular acidosis10.5FLCN, KIT, MME
27benign vaginal carcinosarcoma10.5KIT, KRT20
28hepatorenal syndrome10.5KRT20, MME
29adult epithelioid sarcoma10.5KIT, KRT20
30pneumothorax, primary spontaneous10.5FH, FLCN
31malignant teratocarcinosarcoma10.5KIT, VIM
32adult mesoblastic nephroma10.5MME, VIM
33benign mesothelioma10.5KIT, VIM
34functional colonic disease10.5KIT, SYP
35superficial basal cell carcinoma10.5KRT20, MME
36mixed liposarcoma10.5KIT, VIM
37pediatric ovarian dysgerminoma10.5AMACR, MME, PAX2
38fibrous synovial sarcoma10.5KRT20, MME
39taylor's syndrome10.5AMACR, KRT20
40nerve root neoplasm10.5KIT, VIM
41rectum mucinous adenocarcinoma10.5PAX2, VIM
42pancreatic invasive mucinous cystadenocarcinoma10.4KRT20, MME
43nodular tenosynovitis10.4KRT20, SYP
44urethra adenocarcinoma10.4KRT20, SYP
45sensory system cancer10.4KIT, SYP
46anovulation10.4SYP, VIM
47familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.4SYP, VIM
48vulvar alveolar soft part sarcoma10.4KRT20, SYP
49small intestine cancer10.4KRT20, MME
50bone benign neoplasm10.4KRT20, SYP

Graphical network of the top 20 diseases related to Oxyphilic Adenoma:



Diseases related to oxyphilic adenoma

Symptoms for Oxyphilic Adenoma

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HPO human phenotypes related to Oxyphilic Adenoma:

id Description Frequency HPO Source Accession
1 neoplasm HP:0002664
2 abnormality of metabolism/homeostasis HP:0001939

Drugs & Therapeutics for Oxyphilic Adenoma

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Drugs for Oxyphilic Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Technetium Tc 99m Sestamibi33
2Radiopharmaceuticals362

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney CancerRecruitingNCT01767636Phase 2
2Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of SamplesCompletedNCT00001814
3Study of 99mTc-Sestamibi SPECT/CT Imaging for the Preoperative Diagnosis of Renal OncocytomaRecruitingNCT02160925
4Evaluation of Diagnostic Value of Molecular Markers in Renal CancerTerminatedNCT00491621

Search NIH Clinical Center for Oxyphilic Adenoma


Cochrane evidence based reviews: adenoma, oxyphilic

Genetic Tests for Oxyphilic Adenoma

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Anatomical Context for Oxyphilic Adenoma

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MalaCards organs/tissues related to Oxyphilic Adenoma:

33
Breast, Kidney, Thyroid, Prostate, Small intestine, Colon, Endothelial

Animal Models for Oxyphilic Adenoma or affiliated genes

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MGI Mouse Phenotypes related to Oxyphilic Adenoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.8FLCN, KIT, LGALS3, MT-ND6, RASSF1
2MP:00053847.0FH, FLCN, KIT, LGALS3, MT-ND6, PAX2
3MP:00053856.9FLCN, KIT, KRT8, LGALS3, MT-ND6, PAX2
4MP:00053766.0AMACR, FH, FLCN, KIT, KRT8, LGALS3

Publications for Oxyphilic Adenoma

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Articles related to Oxyphilic Adenoma:

idTitleAuthorsYear
1
Ultrastructural study of glycogen-rich oxyphilic adenoma of the nasopharyngeal minor salivary gland. (3927580)
1985
2
Oxyphilic adenoma of the parotid gland. Identification with 99mTc-pertechnetate. (674638)
1978
3
The angiographic appearance of benign renal oxyphilic adenoma. (973655)
1976
4
Oxyphilic adenoma of the human thyroid. A morphological and biochemical study. (4118915)
1973
5
Oxyphilic adenoma of the larynx. (5027594)
1972
6
Onkocytoma (oxyphilic adenoma) of the caruncle. (6036309)
1967
7
OXYPHILIC ADENOMA (ONCOCYTOMA) OF THE LARYNX; PRESENTATION OF A CASE. (14310177)
1965
8
Oxyphilic adenoma of the parotid gland; report of a case. (13172681)
1954

Variations for Oxyphilic Adenoma

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Clinvar genetic disease variations for Oxyphilic Adenoma:

5
id Gene Variation Type Significance SNP ID Assembly Location
1MT-ND6NC_012920.1: m.14248dupCduplicationPathogenic

Expression for genes affiliated with Oxyphilic Adenoma

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Search GEO for disease gene expression data for Oxyphilic Adenoma.

Pathways for genes affiliated with Oxyphilic Adenoma

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Pathways related to Oxyphilic Adenoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.2PAX2, SYP, VIM

GO Terms for genes affiliated with Oxyphilic Adenoma

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Biological processes related to Oxyphilic Adenoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1stem cell differentiationGO:00488639.8KIT, PAX2

Sources for Oxyphilic Adenoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet