Aliases & Classifications for Pain Agnosia

MalaCards integrated aliases for Pain Agnosia:

Name: Pain Agnosia 12 14
Analgesia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060145

Summaries for Pain Agnosia

Disease Ontology : 12 An agnosia that is a loss of the ability to perceive and process pain.

MalaCards based summary : Pain Agnosia, also known as analgesia, is related to chronic pain requiring intraspinal analgesia and neuropathy, hereditary sensory and autonomic, type v. An important gene associated with Pain Agnosia is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Ketamine and Nalbuphine have been mentioned in the context of this disorder. Affiliated tissues include colon, liver and brain, and related phenotypes are behavior/neurological and homeostasis/metabolism

Related Diseases for Pain Agnosia

Diseases related to Pain Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 216)
id Related Disease Score Top Affiliating Genes
1 chronic pain requiring intraspinal analgesia 11.8
2 neuropathy, hereditary sensory and autonomic, type v 11.0
3 autoimmune inner ear disease 10.8 CNR1 TRPV1
4 congenital insensitivity to pain with hyperhidrosis 10.8
5 congenital insensitivity to pain with severe intellectual disability 10.8
6 insensitivity to pain, congenital 10.8
7 non-gestational choriocarcinoma 10.8 POMC TAC1
8 cystic hygroma lethal cleft palate 10.8 CNR1 OPRM1
9 hepatic vascular disease 10.7 POMC TRPV1
10 placenta accreta 10.7 OPRM1 TAC1 TRPV1
11 cyclotropia 10.7 OPRK1 OPRM1
12 boutonneuse fever 10.7 LIPN TAC1
13 adult mesenchymal chondrosarcoma 10.6 PDYN POMC
14 dyspepsia 10.6 CCK TAC1
15 chondroma 10.6 CCK POMC TRPV1
16 spinal canal intradural extramedullary neoplasm 10.6 LIPN TAC1 TRPV1
17 focal hand dystonia 10.6 OXT TAC1
18 inherited metabolic disorder 10.6 CNR1 POMC TRPV1
19 scleral staphyloma 10.6 CCK HTR7 TRPV1
20 sweat gland cancer 10.6 CCK OPRM1 TAC1
21 dementia - subcortical 10.6 CNR1 OPRM1
22 transsexualism 10.6 CNR1 HTR7 PDYN
23 spondylolysis 10.6 OXT POMC TRPV1
24 cutaneous porphyria 10.5 CNR1 TRPV1
25 perinatal necrotizing enterocolitis 10.5 CCK CNR1 POMC
26 chronic tympanitis 10.5 CCK OPRM1 PDYN TRPV1
27 uterine corpus adenocarcinofibroma 10.5 LIPN OXT POMC
28 rhabdoid cancer 10.5 PDYN POMC
29 keratosis 10.5 HTR7 OXT POMC
30 adenocarcinoma in situ 10.5 CCK PDYN
31 acute female pelvic peritonitis 10.4 OPRK1 OPRM1 PDYN POMC
32 cervicitis 10.4 CCK OPRK1 OPRM1 TRPV1
33 myositis fibrosa 10.4 CCK HTR7 TAC1 TRPV1
34 heroin dependence 10.4 CNR1 OPRK1 OPRM1 POMC
35 suppurative periapical periodontitis 10.3 OPRK1 OPRM1 PDYN POMC TRPV1
36 x-linked dominant intellectual disability-epilepsy syndrome 10.3 CNR1 OPRK1
37 autoimmune disease of central nervous system 10.3 CNR1 HTR7 OPRM1 PDYN POMC
38 balanoposthitis 10.2 PDYN PSENEN
39 hallucinogen dependence 10.0 CNR1 OPRK1 OPRL1 OPRM1 PDYN POMC
40 epidural abscess 10.0
41 horner's syndrome 10.0
42 neuropathy 9.8
43 cerebritis 9.7
44 aneurysm 9.7
45 back pain 9.7
46 postherpetic neuralgia 9.7
47 morphine dependence 9.7
48 dwarfism 9.7
49 agnosia 9.7
50 paralytic ileus 9.6

Graphical network of the top 20 diseases related to Pain Agnosia:



Diseases related to Pain Agnosia

Symptoms & Phenotypes for Pain Agnosia

MGI Mouse Phenotypes related to Pain Agnosia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.03 TRPV1 CCK CNR1 HTR7 OPRK1 OPRL1
2 homeostasis/metabolism MP:0005376 9.93 AP1M2 CCK CNR1 HTR7 LIPN OPRK1
3 adipose tissue MP:0005375 9.8 CNR1 OPRM1 OXT PDYN POMC TRPV1
4 integument MP:0010771 9.7 CNR1 HTR7 OPRK1 OPRL1 OPRM1 OXT
5 nervous system MP:0003631 9.32 TRPV1 CCK CNR1 HTR7 OPRK1 OPRL1

Drugs & Therapeutics for Pain Agnosia

Drugs for Pain Agnosia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 636)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 6740-88-1 3821
2
Nalbuphine Approved Phase 4,Phase 2,Phase 3,Phase 1 20594-83-6 5360630 5311304
3
Ketorolac Approved Phase 4,Phase 3,Phase 2,Phase 1 74103-06-3, 66635-83-4 3826
4
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 57-27-2 5288826
5
Bupivacaine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 2180-92-9, 38396-39-3 2474
6
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 437-38-7 3345
7
Levobupivacaine Approved Phase 4,Phase 3,Phase 2 27262-47-1 92253
8
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 84057-95-4 71273 175805
9
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 103-90-2 1983
10
Clonidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 4205-90-7 2803
11
Sufentanil Approved, Investigational Phase 4,Phase 2,Phase 3,Early Phase 1 56030-54-7 41693
12
Tramadol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 27203-92-5 33741
13
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-43-4 5816
14 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
15
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
16
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
17
Dezocine Approved Phase 4 53648-55-8 40841 3033053
18
Flurbiprofen Approved, Investigational Phase 4 5104-49-4 3394
19
Palonosetron Approved, Investigational Phase 4 135729-61-2, 119904-90-4, 135729-56-5 148211
20
Pentazocine Approved, Vet_approved Phase 4 359-83-1 441278
21
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
22
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
23
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 2078-54-8 4943
24
Remifentanil Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 132875-61-7 60815
25
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1 76-42-6 5284603
26
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 28523-86-6 5206
27
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 60142-96-3 3446
28
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 137-58-6 3676
29
Nitric Oxide Approved Phase 4 10102-43-9 145068
30
Benzoic Acid Approved Phase 4 65-85-0 243
31
Mineral oil Approved, Vet_approved Phase 4,Phase 3 8042-47-5
32
Prilocaine Approved Phase 4,Phase 2,Phase 3 721-50-6 4906
33
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
34
Magnesium Sulfate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 7487-88-9 24083
35
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1 148553-50-8 5486971
36
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
37 Ramosetron Approved Phase 4,Phase 3,Phase 2 132036-88-5
38
Codeine Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1 76-57-3 5284371
39
Guaifenesin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
40
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2 22204-53-1 1302 156391
41
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
42
Droperidol Approved, Vet_approved Phase 4,Phase 3 548-73-2 3168
43
Meperidine Approved Phase 4,Phase 3,Phase 2 57-42-1 4058
44
Tetracaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 94-24-6 5411
45
Chloroprocaine Approved Phase 4,Phase 3,Phase 2 133-16-4 8612
46
Procaine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 59-46-1 4914
47
Terbutaline Approved Phase 4 23031-25-6 5403
48
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263
49
Diphenhydramine Approved Phase 4,Phase 3 58-73-1, 147-24-0 3100
50
Histamine Approved, Investigational Phase 4,Phase 3 75614-87-8, 51-45-6 774

Interventional clinical trials:

(show top 50) (show all 3170)

id Name Status NCT ID Phase Drugs
1 Ketamine and Postoperative Analgesia in Children Unknown status NCT00200564 Phase 4 ketamine
2 Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic Unknown status NCT01543165 Phase 4 Ketorolac and nefopam balanced analgesia;Balanced analgesia using ketorolac and morphine;Pain control with single analgesics (ketorolac)
3 Postoperative Patient Controlled Epidural Analgesia After Total Knee Arthroplasty With 2ug/ml Fentanyl Combine With 0.2% Ropivacaine or 0.2% Levobupivcaine Unknown status NCT01158586 Phase 4 Levobupivacaine
4 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
5 Perioperative Analgesia by Femoral Perineural Catheter for Femoral Neck Fracture - Study KTcol Unknown status NCT01052974 Phase 4 ropivacaine
6 Analgesia After Total Knee Arthroplasty Unknown status NCT00869037 Phase 4 Periarticular Injection;CFNB + Posterior Capsular Injection
7 Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Total Knee Arthroplasty --- A Randomized Controlled Trial Unknown status NCT02284620 Phase 4
8 Comparison of Three Kinds of Postoperative Analgesia After Total Knee Arthroplasty Unknown status NCT02094339 Phase 4 ropivacaine;ropivacaine;opioid
9 The Efficacy and Optimal Dose of Sufentanil in Patient Controlled Analgesia After Moderate Surgery Unknown status NCT02503826 Phase 4 Sufentanil;Sufentanil;Sufentanil;Midazolam;propofol;cisatracurium
10 Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery Unknown status NCT00532662 Phase 4 S(+)-ketamine
11 Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream Unknown status NCT01785693 Phase 4 levobupivacaine, clonidine
12 Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post Laparotomy Unknown status NCT02523846 Phase 4 morphine
13 Comparison of Two Kinds of Postoperative Analgesia After Amputation Unknown status NCT02114463 Phase 4 ropivacaine;flurbiprofen
14 Home Infusors for Analgesia After Foot Surgery Unknown status NCT00600899 Phase 4
15 Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA) Unknown status NCT01281891 Phase 4 LIA;I/T morphine
16 Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial Unknown status NCT02300480 Phase 4
17 Effect of Mu-opioid Receptor Genetics on 3 Doses of Spinal Morphine for Postoperative Analgesia After Cesarean Section Unknown status NCT01465191 Phase 4 Morphine
18 Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy Unknown status NCT01698203 Phase 4 ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun);Placebo;ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
19 Controlled Release of Oxycodone 10 mg In Pre-Medication For The Post Operative Analgesia In Elective Laparoscopic Bilateral Inguinal Hernia And Elective Laparoscopic Cholecystectomy Unknown status NCT00480142 Phase 4 Oxycodone 10 mg
20 Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section Unknown status NCT02279628 Phase 4 Ropivacaine;Morphine
21 The Analgesic Efficacy of Periarticular Infiltration of Local Anaesthetic for Total Hip Replacement Unknown status NCT01312077 Phase 4 Levobupivacaine;Intrathecal morphine
22 A Comparison of Two Anaesthetic Methods of Protecting Heart Tissue During Cardiac Surgery Unknown status NCT00244283 Phase 4 Sevoflurane
23 Optimal Multimodal Analgesia in Abdominal Hysterectomy Unknown status NCT00209872 Phase 4 Gabapentin;Lidocaine;S-ketamine
24 Fast-release Orodispersible Tramadol as Analgesia in Termination of Pregnancy by Vacuum Aspiration. Unknown status NCT02416141 Phase 4 fast release oro dispersible tramadol 50 mg
25 MEOPA Versus Local Anesthesia for Analgesia During Chorionic Villus Sampling. Unknown status NCT02573987 Phase 4 Equimolar Mix of Oxygen and Nitrogen Monoxide;Lidocaïn
26 Suprascapular Nerve Block as Postoperative Analgesia After Artroscopic Shoulder Surgery Unknown status NCT02576223 Phase 4 Ropivacaine hydrochloride;Isotonic Saline
27 Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice Unknown status NCT01303614 Phase 4 Lidocaine-Prilocaine cream;placebo
28 The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia Unknown status NCT02535273 Phase 4 Dexmedetomidine;Lidocaine;Low-dose Dexmedetomidine;Moderate-dose Dexmedetomidine;High-dose Dexmedetomidine;normal saline
29 Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically Unknown status NCT02355093 Phase 4 ropivacaine
30 A Randomized, Double-blind Controlled Trial of Bupivacaine Extended-release Liposome Injection for Postsurgical Analgesia in Patients Undergoing Open-reduction Internal Fixation of the Distal Radius Unknown status NCT02515851 Phase 4 Exparel
31 Perioperative Analgesia After Knee Arthroplasty Unknown status NCT01225484 Phase 4
32 Lidocaine as Local Anesthetics in Children Under Ketamine Sedation Unknown status NCT02205502 Phase 4 Lidocaine;Normal saline
33 Effect of Intraperitoneal Nebulisation of Magnesium Sulphate for Analgesia Following Laparoscopic Cholecystectomy Unknown status NCT01542697 Phase 4 intraperitoneal nebulisation of magnesium sulphate
34 The Effect of Analgesia Based Sedation Protocol on Brain Function of Critical Care Patients Unknown status NCT02078583 Phase 4 Fentanyl;Remifentanil;Normal saline
35 Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Hip Arthroplasty Unknown status NCT00864409 Phase 4 ropivacaine 0,2%;saline.9%
36 Minimum Effective Dose (MED) & Epidural Bupivacaine Unknown status NCT02116842 Phase 4 0.1% bupivacaine;0.075% bupivacaine;40 µg fentanyl
37 Preventing Pain After Heart Surgery Unknown status NCT01480765 Phase 4 Pregabalin;Ketamine infusion;Placebo capsules;Placebo infusion
38 Dexamethasone and Block Duration in Upper Extremity Unknown status NCT01756573 Phase 4 Dexamthsone;Bupivacaine
39 Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism Unknown status NCT02480088 Phase 4 Ramosetron;Palonosetron
40 Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair Unknown status NCT01756560 Phase 4 dexamethsone;Bupivacaine
41 Serratus Anterior Plane Block Versus Paravertebral Block for Postmastectomy Analgesia Unknown status NCT02103946 Phase 4
42 Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies Unknown status NCT00792389 Phase 4
43 Quadratus Lumborum Block for Percutaneous Nephrostomy Unknown status NCT02121951 Phase 4 MAC
44 Postoperative Analgesia in Laminectomy Unknown status NCT02255955 Phase 4 550 mg naproxen sodium and 30mg codeine;300 mg paracetamol and 30 mg codeine;placebo tablet
45 Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy Unknown status NCT00209885 Phase 4 Gabapentin;S-ketamine;Lidocaine;Droperidol
46 Lidocaine Patch for Postoperative Analgesia After Laparoscopic Cholecystectomy Unknown status NCT01485939 Phase 4
47 Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor Unknown status NCT01621230 Phase 4 epidural 0.125% bupivacaine with fentanyl 2 mcg/cc infusion;fentanyl 10 mcg/cc epidural infusion
48 Percutaneous Ketamine Versus Lidocaine or Placebo, for Post-Surgery Analgesia, in Patients Undergoing Laparoscopic Partial Lung Resection Unknown status NCT00822133 Phase 4 lidocaine;ketamine;non-active drug cream
49 The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement Unknown status NCT01312415 Phase 4 Levobupivacaine;Intrathecal morphine
50 In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction? Unknown status NCT01576770 Phase 4 Gebauer's Ethyl Chloride

Search NIH Clinical Center for Pain Agnosia

Genetic Tests for Pain Agnosia

Anatomical Context for Pain Agnosia

MalaCards organs/tissues related to Pain Agnosia:

39
Colon, Liver, Brain, Bone, Lung, Heart, Skin

Publications for Pain Agnosia

Articles related to Pain Agnosia:

id Title Authors Year
1
Pain agnosia and self-injury in the syndrome of reversible somatotropin deficiency (psychosocial dwarfism). ( 5068666 )
1972

Variations for Pain Agnosia

Expression for Pain Agnosia

Search GEO for disease gene expression data for Pain Agnosia.

Pathways for Pain Agnosia

GO Terms for Pain Agnosia

Cellular components related to Pain Agnosia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.98 CNR1 HTR7 OPRK1 OPRL1 OPRM1 PSENEN
2 neuron projection GO:0043005 9.78 OPRK1 OPRL1 OPRM1 TRPV1
3 axon GO:0030424 9.67 CCK CNR1 OPRM1 TAC1
4 neuronal cell body GO:0043025 9.63 CCK OPRK1 PDYN PNOC TAC1 TRPV1
5 perikaryon GO:0043204 9.56 CCK NPFF OPRK1 OPRM1
6 terminal bouton GO:0043195 9.5 AP2M1 CCK OXT
7 clathrin adaptor complex GO:0030131 9.4 AP1M2 AP2M1
8 axon terminus GO:0043679 9.26 NPFF OPRK1 PDYN PNOC
9 dendrite GO:0030425 9.17 CCK NPFF OPRK1 OPRM1 PDYN PNOC
10 plasma membrane GO:0005886 10.23 AP2M1 CNR1 HTR7 OPRK1 OPRL1 OPRM1

Biological processes related to Pain Agnosia according to GeneCards Suite gene sharing:

(show all 30)
id Name GO ID Score Top Affiliating Genes
1 chemical synaptic transmission GO:0007268 9.92 HTR7 NPFF OPRK1 OPRL1 OPRM1 PDYN
2 positive regulation of cytosolic calcium ion concentration GO:0007204 9.88 NPFF OPRL1 OXT TAC1 TRPV1
3 response to ethanol GO:0045471 9.81 CNR1 OPRK1 OPRM1
4 response to morphine GO:0043278 9.8 CNR1 NPFF OPRK1 OPRM1 TAC1
5 excitatory postsynaptic potential GO:0060079 9.77 NPFF OPRM1 TRPV1
6 eating behavior GO:0042755 9.77 CCK OPRK1 OPRL1 OPRM1 OXT
7 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway GO:0007193 9.75 OPRK1 OPRL1 OPRM1
8 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.74 CNR1 HTR7 OPRM1
9 negative regulation of blood pressure GO:0045776 9.73 CNR1 OPRL1 OXT
10 response to cocaine GO:0042220 9.73 CNR1 OPRK1 OPRM1 OXT
11 sensory perception of pain GO:0019233 9.73 CNR1 OPRK1 OPRL1 OPRM1 TAC1 TRPV1
12 positive regulation of blood pressure GO:0045777 9.69 CNR1 NPFF OXT
13 estrous cycle GO:0044849 9.67 OPRK1 OPRL1 OPRM1
14 response to food GO:0032094 9.65 OPRM1 OXT
15 response to pain GO:0048265 9.64 TAC1 TRPV1
16 negative regulation of cAMP biosynthetic process GO:0030818 9.63 OPRL1 OPRM1
17 positive regulation of ossification GO:0045778 9.63 OXT TAC1
18 opioid receptor signaling pathway GO:0038003 9.63 OPRK1 OPRL1 OPRM1
19 maternal behavior GO:0042711 9.62 OPRK1 OXT
20 positive regulation of renal sodium excretion GO:0035815 9.62 OXT TAC1
21 negative regulation of heart rate GO:0010459 9.61 NPFF TAC1
22 behavior GO:0007610 9.61 OPRK1 OPRL1
23 negative regulation of appetite GO:0032099 9.59 CCK NPFF
24 acute inflammatory response to antigenic stimulus GO:0002438 9.58 NPFF OPRM1
25 sensory perception GO:0007600 9.55 OPRK1 OPRL1 OPRM1 PDYN PNOC
26 adenylate cyclase-inhibiting opioid receptor signaling pathway GO:0031635 9.54 OPRK1 OPRM1
27 positive regulation of gastric acid secretion GO:0060454 9.52 OPRL1 TRPV1
28 regulation of sensory perception of pain GO:0051930 9.43 CCK NPFF OPRK1 OPRL1 OPRM1 OXT
29 neuropeptide signaling pathway GO:0007218 9.23 NPFF OPRK1 OPRL1 OPRM1 PDYN PNOC
30 signal transduction GO:0007165 10.25 CCK CNR1 HTR7 OPRK1 OPRL1 OPRM1

Molecular functions related to Pain Agnosia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.54 CCK OXT POMC
2 neuropeptide binding GO:0042923 9.33 OPRK1 OPRL1 OPRM1
3 opioid receptor binding GO:0031628 9.32 PDYN PNOC
4 opioid peptide activity GO:0001515 9.26 PDYN PNOC
5 opioid receptor activity GO:0004985 9.13 OPRK1 OPRL1 OPRM1
6 neuropeptide hormone activity GO:0005184 9.02 CCK NPFF OXT PDYN PNOC

Sources for Pain Agnosia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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31 HMDB
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34 ICD10 via Orphanet
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38 LifeMap
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42 MeSH
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55 OMIM via Orphanet
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60 QIAGEN
65 SNOMED-CT via HPO
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67 TGDB
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70 UMLS via Orphanet
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