MCID: PNC034
MIFTS: 55

Pancreas Disease

Categories: Gastrointestinal diseases, Endocrine diseases

Aliases & Classifications for Pancreas Disease

Summaries for Pancreas Disease

Disease Ontology : 12 An endocrine system disease that is located in the pancreas.

MalaCards based summary : Pancreas Disease, also known as abnormality of the pancreas, is related to endocrine pancreas disease and functioning pituitary adenoma, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Pancreas Disease is INS (Insulin), and among its related pathways/superpathways are Peptide ligand-binding receptors and G alpha (s) signalling events. The drugs Pancrelipase and Secretin have been mentioned in the context of this disorder. Affiliated tissues include pancreas, lung and liver, and related phenotypes are homeostasis/metabolism and adipose tissue

Wikipedia : 72 The pancreas /ˈpæŋkriəs/ is a glandular organ in the digestive system and endocrine system of... more...

Related Diseases for Pancreas Disease

Diseases related to Pancreas Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
id Related Disease Score Top Affiliating Genes
1 endocrine pancreas disease 11.8
2 functioning pituitary adenoma 11.0 POMC SST
3 cutis laxa 10.9 INS POMC
4 african histoplasmosis 10.9 POMC SST
5 pandas 10.9 INS SST
6 cardiomyopathy, dilated, 1jj 10.9 GCG INS
7 cleft lip and palate malrotation cardiopathy 10.9 LEP POMC
8 scleral staphyloma 10.8 CCK SST TRPV1
9 cirrhotic cardiomyopathy 10.8 PRSS1 SCT SPINK1
10 intestinal volvulus 10.8 INS SST
11 semantic agnosia 10.8 CCK POMC TRPV1
12 cervical alveolar soft part sarcoma 10.8 AVP POMC
13 tricuspid valve stenosis 10.8 CCK PRSS1 SCT
14 mody, type iv 10.8 SCT SPINK1
15 acute myocarditis 10.8 INS POMC SST
16 cervical adenosarcoma 10.8 CCK POMC TRPV1
17 ovarian serous cystadenocarcinoma 10.8 CELA1 SPINK1
18 ulcerative blepharitis 10.8 IGF1 INS POMC
19 fibrosarcomatous osteosarcoma 10.8 CCK SST TRPV1
20 repetitive stress injuries 10.8 INS SST
21 spondylolysis 10.8 INS POMC TRPV1
22 mandibular cancer 10.8 CCK SST TRPV1
23 lung giant cell carcinoma 10.8 INS SCT SST
24 hyperlipoproteinemia type iv 10.8 DPP4 INS LEP
25 bagassosis 10.8 AVP POMC
26 prolactin producing pituitary tumor 10.8 IGF1 POMC SST
27 hepatic vascular disease 10.8 LEP POMC TRPV1
28 bile duct cystadenocarcinoma 10.8 CCK SCT SST
29 mononeuritis of upper limb and mononeuritis multiplex 10.8 IGF1 SST
30 diabetic cataract 10.8 ABCC8 INS SST
31 selenium poisoning 10.8 AVP IGF1 INS
32 suppurative periapical periodontitis 10.8 IGF1 POMC TRPV1
33 fibrolamellar carcinoma 10.8 IGF1 INS POMC
34 fetal parvovirus syndrome 10.8 IGF1 INS LEP
35 diencephalic neoplasm 10.8 AVP INS POMC
36 capillary lymphangioma 10.8 IGF1 INS POMC
37 carotid artery thrombosis 10.8 AVP POMC
38 cardiovascular organ benign neoplasm 10.7 IGF1 POMC SST
39 pelvic muscle wasting 10.7 IGF1 INS POMC
40 pervasive developmental disorder 10.7 CCK POMC TRPV1
41 macular retinal edema 10.7 AVP POMC
42 psychogenic movement 10.7 IGF1 POMC SST
43 cervical keratinizing squamous cell carcinoma 10.7 INS PPY SST
44 porokeratosis 10.7 IGF1 INS LEP
45 acute insulin response 10.7 ABCC8 GCG INS
46 lipodystrophy, familial partial, type 2 10.7 INS LEP
47 pemphigus foliaceus 10.7 PPY SST
48 vestibular gland benign neoplasm 10.7 IGF1 POMC SST
49 allergic asthma 10.7 IGF1 INS POMC
50 adrenal cortex disease 10.7 LEP POMC SST

Graphical network of the top 20 diseases related to Pancreas Disease:



Diseases related to Pancreas Disease

Symptoms & Phenotypes for Pancreas Disease

UMLS symptoms related to Pancreas Disease:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, digestive system symptom, gastrointestinal gas

MGI Mouse Phenotypes related to Pancreas Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.93 TRPV1 ABCC8 AVP CCK DPP4 IGF1
2 adipose tissue MP:0005375 9.73 IGF1 INS LEP POMC SLC5A2 TRPV1
3 no phenotypic analysis MP:0003012 9.61 ABCC8 AVP CCK INS POMC SLC5A2
4 renal/urinary system MP:0005367 9.17 AVP IGF1 INS LEP POMC SLC5A2

Drugs & Therapeutics for Pancreas Disease

Drugs for Pancreas Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 934)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pancrelipase Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 53608-75-6
2
Secretin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 108153-74-8
3
Acetaminophen Approved Phase 4,Phase 3,Phase 1 103-90-2 1983
4
Clonidine Approved Phase 4 4205-90-7 2803
5
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Phase 1 84057-95-4 71273 175805
6
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
7
Tramadol Approved, Investigational Phase 4,Phase 2,Phase 3 27203-92-5 33741
8
Cefoperazone Approved Phase 4 62893-19-0 44185
9
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2 55-56-1 9552079 2713
10
Meropenem Approved, Investigational Phase 4,Phase 1,Phase 2 119478-56-7 64778 441130
11
Metronidazole Approved Phase 4,Phase 1 443-48-1 4173
12
Somatostatin Approved Phase 4,Phase 3,Phase 2,Phase 1 38916-34-6, 51110-01-1 53481605
13 lanreotide Approved Phase 4,Phase 3,Phase 2,Phase 1 108736-35-2
14
Octreotide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 83150-76-9 383414 6400441
15
Ceftazidime Approved Phase 4,Phase 1 78439-06-2, 72558-82-8 5481173
16
Tobramycin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 32986-56-4 5496 36294
17
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 437-38-7 3345
18
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2 2078-54-8 4943
19
Diclofenac Approved, Vet_approved Phase 4,Phase 1 15307-86-5 3033
20
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1 59467-70-8 4192
21
Insulin Glargine Approved Phase 4,Phase 3 160337-95-1
22
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
23
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
24
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
25
Dalteparin Approved Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6
26
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
27
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
28
Capecitabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 154361-50-9 60953
29
Benzocaine Approved Phase 4,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
30
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
31
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
32
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
33 Racepinephrine Approved Phase 4,Phase 2
34
Gemcitabine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 95058-81-4 60750
35
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
36
Aztreonam Approved Phase 4,Phase 3,Phase 2 78110-38-0 5362041 5742832
37
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
38
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
39
Sunitinib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 341031-54-7, 557795-19-4 5329102
40
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 169590-42-5 2662
41
Morphine Approved, Investigational Phase 4 57-27-2 5288826
42
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
43
Zinc Approved Phase 4,Phase 3,Phase 2 7440-66-6 32051 23994
44
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263
45
Remifentanil Approved Phase 4 132875-61-7 60815
46
Cilastatin Approved Phase 4 82009-34-5 5280454 6435415
47
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
48
Ketorolac Approved Phase 4,Phase 2,Phase 3,Phase 1 74103-06-3, 66635-83-4 3826
49
Indomethacin Approved, Investigational Phase 4,Phase 3,Phase 2 53-86-1 3715
50
Glycerol Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 56-81-5 753

Interventional clinical trials:

(show top 50) (show all 3387)

id Name Status NCT ID Phase Drugs
1 Effect of an Artificial Pancreas in Patients Undergoing Pancreatic Resection Unknown status NCT00661648 Phase 4
2 Efficacy of Secretin MRCP in the Diagnosis and Follow up of Auto Immune Pancreatitis Unknown status NCT01845467 Phase 4
3 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
4 Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis Unknown status NCT01992198 Phase 4 cefoperazone + metronidazole;Somatostatin;Meropenem
5 Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis Unknown status NCT01376817 Phase 4 Fat emulsion with MCT, LCT, olive oil and omega 3 fatty acids;Fat emulsion with MCT and LCT
6 Prospective Random Comparing Study on EUS-guided Pseudocyst Drainage by Naso-pancreatic Tube and Stents Unknown status NCT01585662 Phase 4
7 Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms Unknown status NCT01673334 Phase 4
8 Lanreotide Autogel Treatment of Patients With Congenital Hyperinsulinism of Infancy Unknown status NCT01070758 Phase 4 Lanreotide autogel
9 Mixed Meal Test in Type 1 Diabetes: Optimization of Artificial Pancreas-Pilot Study Unknown status NCT01800734 Phase 4
10 Disease-Specific Questionnaire in Assessing Quality of Life in Patients With Gastrointestinal-Related Neuroendocrine Tumors Unknown status NCT00454376 Phase 4
11 Impact of Immunonutrition on the Patients With Cystic Fibrosis Unknown status NCT02048592 Phase 4
12 Duration of Antibiotics in Infective Exacerbations of Cystic Fibrosis Unknown status NCT01044719 Phase 4 Ceftazidime;Tobramycin;Meropenem
13 Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy Unknown status NCT01969110 Phase 4
14 Parenteral Fish Oil in Major Laparoscopic Abdominal Surgery Unknown status NCT01819961 Phase 4 MCT/LCT and fish oil;MCT/LCT
15 Prophylactic Pancreatic Duct Stent Placement After ESP of Major Papillary Tumors; Prospective, Randomized Study Unknown status NCT01737463 Phase 4
16 RCT: Difference in Diagnostic Yield Between EUSFNA Needles With and Without a Side Port in Pancreatic Masses Completed NCT02092519 Phase 4
17 Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01350037 Phase 4 alfentanil;remifentanil
18 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy Completed NCT00526331 Phase 4
19 A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died Completed NCT00061438 Phase 4 meropenem
20 Enzyme Suppletion in Exocrine Pancreatic Dysfunction Completed NCT01430234 Phase 4 Panzytrat 25.000 FIP-E units of Lipase
21 Creon After Pancreatic Surgery Completed NCT00535756 Phase 4 Creon;Placebo
22 Evaluation of Pancreatic Tissue Penetration of Meronem® in the Prophylaxis of Septic Complications in Severe Pancreatitis Completed NCT00318994 Phase 4 Meropenem
23 Early Enteral Nutrition for Severe Acute Pancreatitis Completed NCT00995098 Phase 4
24 Imipenem Prophylaxis in Patients With Acute Pancreatitis Completed NCT02897206 Phase 4 Imipenem;Placebo
25 Evaluation of the Digestive and Metabolic Utilisation of Dietary Protein in Patients With Chronic Pancreatitis Completed NCT00957151 Phase 4 Creon
26 Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients Completed NCT00560157 Phase 4
27 Treatment of Acute Pancreatitis With Ketorolac Completed NCT02885441 Phase 4 Ketorolac;Placebo
28 Enteral Nutrition in Acute Pancreatitis Completed NCT01965873 Phase 4
29 Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP) Completed NCT02111707 Phase 4 Rectal indomethacin 100mg one time before or after ERCP
30 Post ERCP Pancreatitis Prevention in Average Risk Patients Completed NCT01784445 Phase 4 Ceftazidime
31 Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant Completed NCT01186562 Phase 4 Sitagliptin;Placebo
32 Dexmedetomidine Versus Placebo in Endoscopic Retrograde Cholangiopancreatography (ERCP) Sedation Completed NCT01070680 Phase 4 Precedex;sodium chlorid 0,9%
33 Activated Protein C in Severe Acute Pancreatitis Completed NCT01017107 Phase 4 Activated protein C
34 Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube Completed NCT00999232 Phase 4 Erythromycin;Placebo
35 Acute Pancreatitis and Acute Fluid Collections Completed NCT00786929 Phase 4 Conservative treatment
36 Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers Completed NCT00222092 Phase 4
37 Use of Polyethylene Glycolic Acid or Tachocomb to Prevent Pancreatic Fistula Following Distal Pancreatectomy Completed NCT01550406 Phase 4
38 Prospective Study of Efficacy of Intra-muscular Vitamin D3 in Tropical Calcific Pancreatitis Completed NCT00956839 Phase 4 Vitamin D3 (Cholecalciferol)
39 Role of Octreotide in Preventing Pancreatic Fistula After Pancreaticoduodenectomy (PD) in Patients With Soft Pancreas Completed NCT01301222 Phase 4 Inj. Octreotide
40 Enteral Nutrition in the Treatment of Pancreatic Fistulas - A Prospective Study Completed NCT01025414 Phase 4 enteral nutrition;Parenteral nutrition
41 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
42 Electro Flo 5000 and Vest Therapy Completed NCT02277626 Phase 4
43 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
44 Effect of an Artificial Pancreas in Patients Undergoing Hepatic Resection Completed NCT00659698 Phase 4
45 Switch From Calcineurin Inhibitor to Belatacept in Pancreas Transplant Recipients Completed NCT02103855 Phase 4 Belatacept
46 Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency Completed NCT01327703 Phase 4 Panzytrat® 25,000;Kreon® 25,000
47 A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of Age Completed NCT01100606 Phase 4 EUR-1008 (APT-1008);EUR-1008 (APT-1008)
48 PR-018: An Open-Label, Safety Extension of Study PR-011 Completed NCT01131507 Phase 4 EUR-1008 (APT-1008)
49 Pharmacokinetics of Piperacillin, Given as Continuous Infusion to Patients With Cystic Fibrosis Completed NCT01983787 Phase 4
50 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4 early enteral nutrition;Delayed enteral nutrition

Search NIH Clinical Center for Pancreas Disease

Genetic Tests for Pancreas Disease

Genetic tests related to Pancreas Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Pancreas 29

Anatomical Context for Pancreas Disease

MalaCards organs/tissues related to Pancreas Disease:

39
Pancreas, Lung, Liver, Testes, Kidney, T Cells, Colon

Publications for Pancreas Disease

Articles related to Pancreas Disease:

(show top 50) (show all 70)
id Title Authors Year
1
Impact of non-alcoholic fatty pancreas disease on glucose metabolism. ( 28371475 )
2017
2
Non-alcoholic fatty pancreas disease. ( 28069746 )
2017
3
Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice. ( 28442507 )
2017
4
The epidemiological and economic effects from systematic depopulation of Norwegian marine salmon farms infected with pancreas disease virus. ( 27664454 )
2016
5
Ballan wrasse (Labrus bergylta Ascanius) is not susceptible to pancreas disease caused by salmonid alphavirus subtype 2 and 3. ( 27859355 )
2016
6
Vaccination against pancreas disease in Atlantic salmon, Salmo salar L., reduces shedding of salmonid alphavirus. ( 27496170 )
2016
7
Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease. ( 27678349 )
2016
8
Experimental Piscine orthoreovirus infection mediates protection against pancreas disease in Atlantic salmon (Salmo salar). ( 27769313 )
2016
9
The epidemiology of pancreas disease in salmonid aquaculture: a summary of the current state of knowledge. ( 27136332 )
2016
10
Mapping and validation of a major QTL affecting resistance to pancreas disease (salmonid alphavirus) in Atlantic salmon (Salmo salar). ( 25990876 )
2015
11
Nonalcoholic fatty pancreas disease and Nonalcoholic fatty liver disease: more than ectopic fat. ( 26201937 )
2015
12
Prevalence of Non-Alcoholic Fatty Pancreas Disease (NAFPD) and its risk factors among adult medical check-up patients in a private hospital: a large cross sectional study. ( 26652175 )
2015
13
Comparison of transcriptomic responses to pancreas disease (PD) and heart and skeletal muscle inflammation (HSMI) in heart of Atlantic salmon (Salmo salar L). ( 26232631 )
2015
14
Xenopus as a Model for GI/Pancreas Disease. ( 26236566 )
2015
15
Space-time modelling of the spread of pancreas disease (PD) within and between Norwegian marine salmonid farms. ( 26104836 )
2015
16
The economic benefits of disease triggered early harvest: A case study of pancreas disease in farmed Atlantic salmon from Norway. ( 26297077 )
2015
17
Enigmatic ectopic fat: prevalence of nonalcoholic fatty pancreas disease and its associated factors in a Chinese population. ( 24572250 )
2014
18
Clinical signature and pathogenetic factors of diabetes associated with pancreas disease (T3cDM): a prospective observational study in surgical patients. ( 24974302 )
2014
19
Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L. ( 25168106 )
2014
20
Cross-sectional study to investigate the presence of salmon pancreas disease virus in wild and feral fish populations in 10A lakes, Los Lagos Region, Chile. ( 24382013 )
2014
21
Non-alcoholic fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. ( 24657938 )
2014
22
Transmission dynamics of pancreas disease (PD) in a Norwegian fjord: aspects of water transport, contact networks and infection pressure among salmon farms. ( 25254274 )
2014
23
Clinical manifestations of pancreas disease outbreaks in Norwegian marine salmon farming - variations due to salmonid alphavirus subtype. ( 24661057 )
2014
24
An experimental means of transmitting pancreas disease in Atlantic salmon Salmo salar L. fry in freshwater. ( 25297529 )
2014
25
The serum proteome of Atlantic salmon, Salmo salar, during pancreas disease (PD) following infection with salmonid alphavirus subtype 3 (SAV3). ( 24145143 )
2013
26
Seasonal increase in sea temperature triggers pancreas disease outbreaks in Norwegian salmon farms. ( 23980568 )
2013
27
Mortality related to pancreas disease in Norwegian farmed salmonid fish, Salmo salar L. and Oncorhynchus mykiss (Walbaum). ( 23311767 )
2013
28
Estimation of the reproduction number of salmon pancreas disease virus subtype 3 in homogeneously mixed populations of Norwegian farmed Atlantic salmon. ( 23810623 )
2013
29
Transmission dynamics of pancreas disease (PD) in a Norwegian fjord: aspects of water transport, contact networks and infection pressure among salmon farms. ( 23452114 )
2013
30
Immune parameters correlating with reduced susceptibility to pancreas disease in experimentally challenged Atlantic salmon (Salmo salar). ( 23306092 )
2013
31
The association between nonalcoholic fatty pancreas disease and diabetes. ( 23671610 )
2013
32
Comparative cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD). ( 23200434 )
2013
33
Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic fatty pancreas disease. ( 23285260 )
2012
34
Cohort study of effect of vaccination on pancreas disease in Norwegian salmon aquaculture. ( 23209075 )
2012
35
Risk map and spatial determinants of pancreas disease in the marine phase of Norwegian Atlantic salmon farming sites. ( 23006469 )
2012
36
Detection of salmon pancreas disease virus in the faeces and mucus of Atlantic salmon, Salmo salar L., by real-time RT-PCR and cell culture following experimental challenge. ( 22924477 )
2012
37
Quality of raw and smoked fillets from clinically healthy Atlantic salmon, Salmo salar L., following an outbreak of pancreas disease (PD). ( 22924617 )
2012
38
Formulations combining CpG containing oliogonucleotides and poly I:C enhance the magnitude of immune responses and protection against pancreas disease in Atlantic salmon. ( 21527278 )
2011
39
A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet. ( 20490316 )
2010
40
Detection of salmonid alphavirus RNA in wild marine fish: implications for the origins of salmon pancreas disease in aquaculture. ( 21133318 )
2010
41
Salmonid alphavirus (SAV) and pancreas disease (PD) in Atlantic salmon, Salmo salar L., in freshwater and seawater sites in Norway from 2006 to 2008. ( 20158578 )
2010
42
Nonalcoholic fatty liver disease is related to nonalcoholic fatty pancreas disease. ( 20871475 )
2010
43
Stochastic modelling of direct costs of pancreas disease (PD) in Norwegian farmed Atlantic salmon (Salmo salar L.). ( 19931201 )
2010
44
Pancreas disease (PD) in sea-reared Atlantic salmon, Salmo salar L., in Norway; a prospective, longitudinal study of disease development and agreement between diagnostic test results. ( 20609035 )
2010
45
Maternal obesity programmes offspring development of non-alcoholic fatty pancreas disease. ( 20170634 )
2010
46
A stochastic model for the assessment of the transmission pathways of heart and skeleton muscle inflammation, pancreas disease and infectious salmon anaemia in marine fish farms in Norway. ( 19811843 )
2010
47
Integration of hydrodynamics into a statistical model on the spread of pancreas disease (PD) in salmon farming. ( 20183963 )
2009
48
Risk factors for pancreas disease (PD) outbreaks in farmed Atlantic salmon and rainbow trout in Norway during 2003-2007. ( 19419787 )
2009
49
Autophagy and pancreas disease. ( 18714176 )
2008
50
Heritability of mortality in response to a natural pancreas disease (SPDV) challenge in Atlantic salmon, Salmo salar L., post-smolts on a West of Ireland sea site. ( 19017068 )
2008

Variations for Pancreas Disease

Expression for Pancreas Disease

Search GEO for disease gene expression data for Pancreas Disease.

Pathways for Pancreas Disease

GO Terms for Pancreas Disease

Cellular components related to Pancreas Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.83 AVP CCK CELA1 DPP4 GCG IGF1
2 extracellular space GO:0005615 9.47 AVP CCK CELA1 CELA3B GCG IGF1

Biological processes related to Pancreas Disease according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.72 CCK IGF1 INS
2 positive regulation of MAPK cascade GO:0043410 9.69 IGF1 INS LEP
3 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.63 IGF1 INS LEP
4 digestion GO:0007586 9.61 PPY PRSS1 SST
5 positive regulation of glycolytic process GO:0045821 9.58 IGF1 INS
6 glucose homeostasis GO:0042593 9.58 INS LEP
7 negative regulation of release of cytochrome c from mitochondria GO:0090201 9.57 AVP IGF1
8 positive regulation of glycogen biosynthetic process GO:0045725 9.56 IGF1 INS
9 cell-cell signaling GO:0007267 9.55 AVP INS POMC PPY SST
10 response to pH GO:0009268 9.54 ABCC8 TRPV1
11 response to heat GO:0009408 9.54 IGF1 SST TRPV1
12 positive regulation of insulin receptor signaling pathway GO:0046628 9.52 INS LEP
13 regulation of appetite GO:0032098 9.49 POMC PPY
14 negative regulation of appetite GO:0032099 9.48 CCK LEP
15 positive regulation of cAMP biosynthetic process GO:0030819 9.43 AVP GCG SCT
16 positive regulation of cell proliferation GO:0008284 9.43 AVP CCK DPP4 IGF1 INS LEP
17 positive regulation of glutamate secretion GO:0014049 9.4 AVP CCK
18 bone mineralization involved in bone maturation GO:0035630 9.32 IGF1 LEP
19 regulation of insulin secretion GO:0050796 8.92 ABCC8 DPP4 GCG LEP

Molecular functions related to Pancreas Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.8 CELA1 CELA3B DPP4 PRSS1 PRSS58
2 receptor binding GO:0005102 9.73 AVP DPP4 GCG LEP POMC PPY
3 serine-type endopeptidase activity GO:0004252 9.72 CELA1 CELA3B DPP4 PRSS1 PRSS58
4 serine-type peptidase activity GO:0008236 9.55 CELA1 CELA3B DPP4 PRSS1 PRSS58
5 insulin-like growth factor receptor binding GO:0005159 9.43 IGF1 INS
6 glucose:sodium symporter activity GO:0005412 9.37 SLC5A2 SLC5A4
7 hormone activity GO:0005179 9.32 AVP CCK GCG IGF1 INS LEP
8 neuropeptide hormone activity GO:0005184 9.13 AVP CCK PPY

Sources for Pancreas Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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