MCID: PNC094
MIFTS: 16

Pancreatic Cancer 1

Categories: Genetic diseases, Endocrine diseases, Cancer diseases, Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Pancreatic Cancer 1

MalaCards integrated aliases for Pancreatic Cancer 1:

Name: Pancreatic Cancer 1 53 71 28
Pancreatic Cancer, Susceptibility to, 1 53 13
Pnca1 53 71

Classifications:



External Ids:

OMIM 53 606856
MedGen 39 C1847351
MeSH 41 D010190

Summaries for Pancreatic Cancer 1

UniProtKB/Swiss-Prot : 71 Pancreatic cancer 1: A malignant neoplasm of the pancreas. Tumors can arise from both the exocrine and endocrine portions of the pancreas, but 95% of them develop from the exocrine portion, including the ductal epithelium, acinar cells, connective tissue, and lymphatic tissue.

MalaCards based summary : Pancreatic Cancer 1, is also known as pancreatic cancer, susceptibility to, 1. An important gene associated with Pancreatic Cancer 1 is PALLD (Palladin, Cytoskeletal Associated Protein). The drugs Capecitabine and Gemcitabine have been mentioned in the context of this disorder. Affiliated tissues include pancreas.

Description from OMIM: 606856

Related Diseases for Pancreatic Cancer 1

Symptoms & Phenotypes for Pancreatic Cancer 1

Clinical features from OMIM:

606856

Drugs & Therapeutics for Pancreatic Cancer 1

Drugs for Pancreatic Cancer 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capecitabine Approved, Investigational Phase 1, Phase 2 154361-50-9 60953
2
Gemcitabine Approved Phase 1, Phase 2 95058-81-4 60750
3 Antimetabolites Phase 1, Phase 2
4 Antimetabolites, Antineoplastic Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Neoadjuvant Accelerated Short Course Radiation Therapy With Photons and Capecitabine for Resectable Pancreatic Cancer Terminated NCT00889187 Phase 1, Phase 2 Capecitabine

Search NIH Clinical Center for Pancreatic Cancer 1

Genetic Tests for Pancreatic Cancer 1

Genetic tests related to Pancreatic Cancer 1:

# Genetic test Affiliating Genes
1 Pancreatic Cancer 1 28 PALLD

Anatomical Context for Pancreatic Cancer 1

MalaCards organs/tissues related to Pancreatic Cancer 1:

38
Pancreas

Publications for Pancreatic Cancer 1

Variations for Pancreatic Cancer 1

ClinVar genetic disease variations for Pancreatic Cancer 1:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 PALLD NM_001166110.1(PALLD): c.415C> T (p.Pro139Ser) single nucleotide variant risk factor rs121908291 GRCh37 Chromosome 4, 169799457: 169799457

Expression for Pancreatic Cancer 1

Search GEO for disease gene expression data for Pancreatic Cancer 1.

Pathways for Pancreatic Cancer 1

GO Terms for Pancreatic Cancer 1

Sources for Pancreatic Cancer 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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