PNCA3
MCID: PNC063
MIFTS: 10

Pancreatic Cancer Susceptibility 3 (PNCA3) malady

Categories: Genetic diseases, Endocrine diseases, Cancer diseases

Aliases & Classifications for Pancreatic Cancer Susceptibility 3

Aliases & Descriptions for Pancreatic Cancer Susceptibility 3:

Name: Pancreatic Cancer Susceptibility 3 24
Pnca3 24

Classifications:



Summaries for Pancreatic Cancer Susceptibility 3

MalaCards based summary : Pancreatic Cancer Susceptibility 3, also known as pnca3, is related to pancreatic cancer and pancreatic cancer 3. An important gene associated with Pancreatic Cancer Susceptibility 3 is PALB2 (Partner And Localizer Of BRCA2). The drugs Metformin and insulin have been mentioned in the context of this disorder.

Related Diseases for Pancreatic Cancer Susceptibility 3

Diseases in the Pancreatic Cancer Susceptibility 4 family:

Pancreatic Cancer Susceptibility 1 Pancreatic Cancer Susceptibility 2
Pancreatic Cancer Susceptibility 3

Diseases related to Pancreatic Cancer Susceptibility 3 via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 pancreatic cancer 10.9
2 pancreatic cancer 3 10.8

Symptoms & Phenotypes for Pancreatic Cancer Susceptibility 3

Drugs & Therapeutics for Pancreatic Cancer Susceptibility 3

Drugs for Pancreatic Cancer Susceptibility 3 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 14219 4091
2 insulin Phase 4
3 Hypoglycemic Agents Phase 4
4 Insulin, Globin Zinc Phase 4
5 Liver Extracts Phase 4
6
Olaparib Approved Phase 2 763113-22-0 23725625
7 Poly(ADP-ribose) Polymerase Inhibitors Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase
1 Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS) Recruiting NCT02500147 Phase 4
2 Efficacy and Safety of PARPi to Treat Pancreatic Cancer Not yet recruiting NCT02511223 Phase 2
3 Blood Collection From Individuals With Lung Disease for Genetic Studies Completed NCT00362739
4 Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer Recruiting NCT00050752

Search NIH Clinical Center for Pancreatic Cancer Susceptibility 3

Genetic Tests for Pancreatic Cancer Susceptibility 3

Genetic tests related to Pancreatic Cancer Susceptibility 3:

id Genetic test Affiliating Genes
1 Pancreatic Cancer Susceptibility 3 24 PALB2

Anatomical Context for Pancreatic Cancer Susceptibility 3

Publications for Pancreatic Cancer Susceptibility 3

Variations for Pancreatic Cancer Susceptibility 3

Expression for Pancreatic Cancer Susceptibility 3

Search GEO for disease gene expression data for Pancreatic Cancer Susceptibility 3.

Pathways for Pancreatic Cancer Susceptibility 3

GO Terms for Pancreatic Cancer Susceptibility 3

Sources for Pancreatic Cancer Susceptibility 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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