MCID: PNC063

Pancreatic Cancer Susceptibility 3 malady

Genetic diseases (common), Endocrine diseases, Cancer diseases categories

Summaries for Pancreatic Cancer Susceptibility 3

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34MalaCards
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MalaCards: Pancreatic Cancer Susceptibility 3, is also known as pancreatic cancer, susceptibility to, 3 An important gene associated with Pancreatic Cancer Susceptibility 3 is PALB2 (partner and localizer of BRCA2).

Aliases & Classifications for Pancreatic Cancer Susceptibility 3

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Sources:
21GeneTests, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common), Cancer diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

pancreatic cancer susceptibility 3 21
pancreatic cancer, susceptibility to, 3 63


Related Diseases for Pancreatic Cancer Susceptibility 3

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Diseases in the Pancreatic Cancer Susceptibility 2 family:

pancreatic cancer susceptibility 3 Pancreatic Cancer Susceptibility 1

Symptoms for Pancreatic Cancer Susceptibility 3

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Drugs & Therapeutics for Pancreatic Cancer Susceptibility 3

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Pancreatic Cancer Susceptibility 3

Drug clinical trials:

Search ClinicalTrials for Pancreatic Cancer Susceptibility 3

Search NIH Clinical Center for Pancreatic Cancer Susceptibility 3

Search CenterWatch for Pancreatic Cancer Susceptibility 3

Genetic Tests for Pancreatic Cancer Susceptibility 3

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21GeneTests
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Genetic tests related to Pancreatic Cancer Susceptibility 3:

id Genetic test Affiliating Genes
1 Pancreatic Cancer Susceptibility 321 PALB2

Anatomical Context for Pancreatic Cancer Susceptibility 3

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Animal Models for Pancreatic Cancer Susceptibility 3 or affiliated genes

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Publications for Pancreatic Cancer Susceptibility 3

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Variations for Pancreatic Cancer Susceptibility 3

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Sources:
1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Pancreatic Cancer Susceptibility 3:

1 (show all 11)
id Gene Name Type Significance SNP ID Assembly Location
1PALB2NM_024675.3(PALB2): c.3549C> G (p.Tyr1183Ter)single nucleotide variantPathogenic, risk factorrs118203998GRCh37Chr 16, 23614792: 23614792
2PALB2NM_024675.3(PALB2): c.1027C> T (p.Gln343Ter)single nucleotide variantPathogenicrs180177097GRCh38Chr 16, 23635519: 23635519
3PALB2NM_024675.3(PALB2): c.1314delA (p.Phe440Leufs)deletionPathogenicrs515726065GRCh38Chr 16, 23635232: 23635232
4PALB2NM_024675.3(PALB2): c.172_175delTTGT (p.Gln60Argfs)deletionPathogenic, Uncertain significance, risk factorrs180177143GRCh38Chr 16, 23637886: 23637889
5PALB2NM_024675.3(PALB2): c.3116delA (p.Asn1039Ilefs)deletionPathogenic, risk factorrs180177133GRCh38Chr 16, 23614089: 23614089
6PALB2PALB2: c.3202-?_*297del (p.Gly1068_Ser1186delins45)deletionPathogenicGRCh38Chr 16, 23603162: 23603162
7PALB2NM_024675.3(PALB2): c.3256C> T (p.Arg1086Ter)single nucleotide variantPathogenic, risk factorGRCh38Chr 16, 23607958: 23607958
8PALB2NM_024675.3(PALB2): c.3497delG (p.Gly1166Valfs)deletionPathogenicrs180177138GRCh37Chr 16, 23614844: 23614844
9PALB2NM_024675.3(PALB2): c.509_510delGA (p.Arg170Ilefs)deletionPathogenicrs515726124GRCh38Chr 16, 23636036: 23636037
10PALB2NM_024675.3(PALB2): c.72delG (p.Arg26Glyfs)deletionPathogenicrs180177142GRCh38Chr 16, 23638106: 23638106
11PALB2NM_024675.3(PALB2): c.757_758delCT (p.Leu253Ilefs)deletionPathogenicrs180177092GRCh38Chr 16, 23635788: 23635789

Expression for genes affiliated with Pancreatic Cancer Susceptibility 3

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pancreatic Cancer Susceptibility 3

Search GEO for disease gene expression data for Pancreatic Cancer Susceptibility 3.

Pathways for genes affiliated with Pancreatic Cancer Susceptibility 3

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Compounds for genes affiliated with Pancreatic Cancer Susceptibility 3

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GO Terms for genes affiliated with Pancreatic Cancer Susceptibility 3

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Products for genes affiliated with Pancreatic Cancer Susceptibility 3

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pancreatic Cancer Susceptibility 3

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet