MCID: PNC073
MIFTS: 24

Pancreatic Carcinoma, Somatic malady

Endocrine, Cancer categories

Summaries for Pancreatic Carcinoma, Somatic

Sources:
47OMIM, 33MalaCards
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MalaCards: Pancreatic Carcinoma, Somatic, also known as malignant neoplasm of pancreas, is related to pancreas sarcoma and pancreatic ductal carcinoma. An important gene associated with Pancreatic Carcinoma, Somatic is KRAS (Kirsten rat sarcoma viral oncogene homolog), and among its related pathways are Apoptosis Pathway and TGF-beta Signaling Pathway. The compound crcs have been mentioned in the context of this disorder. Affiliated tissues include colon, pancreas and breast, and related mouse phenotypes are tumorigenesis and digestive/alimentary.

Description from OMIM:47 260350

Aliases & Classifications for Pancreatic Carcinoma, Somatic

Sources:
47OMIM, 61UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Endocrine


Aliases & Descriptions:

pancreatic carcinoma, somatic 47
malignant neoplasm of pancreas 61
pancreatic cancer, somatic 47


Related Diseases for Pancreatic Carcinoma, Somatic

Sources:
17GeneCards, 18GeneDecks
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Graphical network of diseases related to Pancreatic Carcinoma, Somatic:



Diseases related to pancreatic carcinoma, somatic

Clinical Features for Pancreatic Carcinoma, Somatic

Sources:
47OMIM
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Clinical features from OMIM:

260350

Clinical synopsis from OMIM:

260350

Drugs & Therapeutics for Pancreatic Carcinoma, Somatic

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Pancreatic Carcinoma, Somatic

Drug clinical trials:

Search ClinicalTrials for Pancreatic Carcinoma, Somatic

Search NIH Clinical Center for Pancreatic Carcinoma, Somatic

Search CenterWatch for Pancreatic Carcinoma, Somatic

Genetic Tests for Pancreatic Carcinoma, Somatic

Anatomical Context for Pancreatic Carcinoma, Somatic

Sources:
33MalaCards
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MalaCards organs/tissues related to Pancreatic Carcinoma, Somatic:

33
Colon, Pancreas, Breast

Animal Models for Pancreatic Carcinoma, Somatic or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Pancreatic Carcinoma, Somatic:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5RBBP8, KRAS, SMAD4
2MP:00053818.3KRAS, ACVR1B, SMAD4
3MP:00053808.1RBBP8, KRAS, ACVR1B, SMAD4
4MP:00107688.0RBBP8, KRAS, ACVR1B, SMAD4
5MP:00053847.9RBBP8, KRAS, ACVR1B, SMAD4

Publications for Pancreatic Carcinoma, Somatic

Genetic Variations for Pancreatic Carcinoma, Somatic

Expression for genes affiliated with Pancreatic Carcinoma, Somatic

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pancreatic Carcinoma, Somatic

Search GEO for disease gene expression data for Pancreatic Carcinoma, Somatic.

Pathways for genes affiliated with Pancreatic Carcinoma, Somatic

Sources:
60Tocris Bioscience, 56SinoBiological, 54Reactome, 38NCBI BioSystems Database, 53R&D Systems, 30KEGG, 12EMD Millipore
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Compounds for genes affiliated with Pancreatic Carcinoma, Somatic

Sources:
45Novoseek
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Compounds related to Pancreatic Carcinoma, Somatic according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1crcs459.1SMAD4, KRAS

GO Terms for genes affiliated with Pancreatic Carcinoma, Somatic

Sources:
16Gene Ontology
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Biological processes related to Pancreatic Carcinoma, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of pathway-restricted SMAD protein phosphorylationGO:0108629.1SMAD4, ACVR1B
2in utero embryonic developmentGO:0017019.1SMAD4, ACVR1B
3negative regulation of cell growthGO:0303089.0SMAD4, ACVR1B
4G1/S transition of mitotic cell cycleGO:0000829.0ACVR1B, RBBP8

Products for genes affiliated with Pancreatic Carcinoma, Somatic

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pancreatic Carcinoma, Somatic

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet