MCID: PNC073
MIFTS: 28

Pancreatic Carcinoma, Somatic malady

Endocrine diseases, Cancer diseases categories

Summaries for Pancreatic Carcinoma, Somatic

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46OMIM, 32MalaCards
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MalaCards: Pancreatic Carcinoma, Somatic, also known as malignant neoplasm of pancreas, is related to pancreatitis and pancreatic cancer. An important gene associated with Pancreatic Carcinoma, Somatic is KRAS (Kirsten rat sarcoma viral oncogene homolog), and among its related pathways are Apoptosis Pathway and TGF-beta Signaling Pathway. The compound crcs have been mentioned in the context of this disorder. Affiliated tissues include colon, pancreas and breast, and related mouse phenotypes are tumorigenesis and digestive/alimentary.

Description from OMIM:46 260350

Aliases & Classifications for Pancreatic Carcinoma, Somatic

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46OMIM, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

pancreatic carcinoma, somatic 46
malignant neoplasm of pancreas 60
pancreatic cancer, somatic 46


Related Diseases for Pancreatic Carcinoma, Somatic

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Pancreatic Carcinoma, Somatic:



Diseases related to pancreatic carcinoma, somatic

Clinical Features for Pancreatic Carcinoma, Somatic

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46OMIM
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Clinical features from OMIM:

260350

Clinical synopsis from OMIM:

260350

Drugs & Therapeutics for Pancreatic Carcinoma, Somatic

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Pancreatic Carcinoma, Somatic

Drug clinical trials:

Search ClinicalTrials for Pancreatic Carcinoma, Somatic

Search NIH Clinical Center for Pancreatic Carcinoma, Somatic

Search CenterWatch for Pancreatic Carcinoma, Somatic

Genetic Tests for Pancreatic Carcinoma, Somatic

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Anatomical Context for Pancreatic Carcinoma, Somatic

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32MalaCards
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MalaCards organs/tissues related to Pancreatic Carcinoma, Somatic:

32
Colon, Pancreas, Breast

Animal Models for Pancreatic Carcinoma, Somatic or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Pancreatic Carcinoma, Somatic:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5RBBP8, KRAS, SMAD4
2MP:00053818.3KRAS, ACVR1B, SMAD4
3MP:00053808.1RBBP8, KRAS, ACVR1B, SMAD4
4MP:00107688.0RBBP8, KRAS, ACVR1B, SMAD4
5MP:00053847.9RBBP8, KRAS, ACVR1B, SMAD4

Publications for Pancreatic Carcinoma, Somatic

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Genetic Variations for Pancreatic Carcinoma, Somatic

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Expression for genes affiliated with Pancreatic Carcinoma, Somatic

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pancreatic Carcinoma, Somatic

Search GEO for disease gene expression data for Pancreatic Carcinoma, Somatic.

Pathways for genes affiliated with Pancreatic Carcinoma, Somatic

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Sources:
59Tocris Bioscience, 55SinoBiological, 53Reactome, 37NCBI BioSystems Database, 52R&D Systems, 29KEGG, 12EMD Millipore
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Compounds for genes affiliated with Pancreatic Carcinoma, Somatic

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44Novoseek
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Compounds related to Pancreatic Carcinoma, Somatic according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1crcs449.1SMAD4, KRAS

GO Terms for genes affiliated with Pancreatic Carcinoma, Somatic

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16Gene Ontology
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Biological processes related to Pancreatic Carcinoma, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of pathway-restricted SMAD protein phosphorylationGO:0108629.1SMAD4, ACVR1B
2in utero embryonic developmentGO:0017019.1SMAD4, ACVR1B
3negative regulation of cell growthGO:0303089.0SMAD4, ACVR1B
4G1/S transition of mitotic cell cycleGO:0000829.0ACVR1B, RBBP8

Products for genes affiliated with Pancreatic Carcinoma, Somatic

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pancreatic Carcinoma, Somatic

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet