MCID: PNC041
MIFTS: 38

Pancreatic Ductal Adenocarcinoma malady

Endocrine diseases category

Aliases & Classifications for Pancreatic Ductal Adenocarcinoma

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Pancreatic Ductal Adenocarcinoma, Aliases & Descriptions:

Name: Pancreatic Ductal Adenocarcinoma 30 9 11 60
 
Ductal Adenocarcinoma of the Pancreas 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


External Ids:

Disease Ontology9 DOID:3498
NCIt38 C9120

Summaries for Pancreatic Ductal Adenocarcinoma

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Disease Ontology:9 A pancreas adenocarcinoma that derives from pancreatic duct cells.

MalaCards based summary: Pancreatic Ductal Adenocarcinoma, also known as ductal adenocarcinoma of the pancreas, is related to adenocarcinoma and pancreatitis. An important gene associated with Pancreatic Ductal Adenocarcinoma is MIR196A2 (microRNA 196a-2), and among its related pathways are miRNAs involved in DDR and MicroRNAs in cancer. Affiliated tissues include pancreas, kidney and lymph node.

Related Diseases for Pancreatic Ductal Adenocarcinoma

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Diseases related to Pancreatic Ductal Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 27)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma11.6
2pancreatitis11.6
3pancreatic cancer10.8
4hypoxia10.7
5autoimmune pancreatitis10.5
6duodenitis10.5
7cholangiocarcinoma10.4
8hepatitis10.4
9cystadenoma10.4
10stomatitis10.4
11acinar cell carcinoma10.3
12renal clear cell carcinoma10.3
13mucinous cystadenocarcinoma10.3
14cystadenocarcinoma10.3
15breast cancer10.2
16cystic fibrosis10.2
17wilms tumor10.2
18hepatitis b10.2
19adenosquamous carcinoma10.2
20pancreatic serous cystadenoma10.2
21gastric adenocarcinoma10.2
22melanoma10.2
23neuroendocrine tumor10.2
24peritonitis10.2
25diffuse gastric cancer10.2
26aneurysm10.2
27endotheliitis10.2

Graphical network of the top 20 diseases related to Pancreatic Ductal Adenocarcinoma:



Diseases related to pancreatic ductal adenocarcinoma

Symptoms for Pancreatic Ductal Adenocarcinoma

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Drugs & Therapeutics for Pancreatic Ductal Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Pancreatic Ductal Adenocarcinoma

Search NIH Clinical Center for Pancreatic Ductal Adenocarcinoma

Genetic Tests for Pancreatic Ductal Adenocarcinoma

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Anatomical Context for Pancreatic Ductal Adenocarcinoma

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MalaCards organs/tissues related to Pancreatic Ductal Adenocarcinoma:

31
Pancreas, Kidney, Lymph node, Liver, Neutrophil, T cells, Breast, Brain, Adipocyte, Prostate, Testis, Myeloid, Testes, Smooth muscle, Skeletal muscle, Colon, Monocytes, Endothelial

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Pancreatic Ductal Adenocarcinoma:
id TissueAnatomical CompartmentCell Relevance
1 PancreasPancreatic Ducts  Affected by disease

Animal Models for Pancreatic Ductal Adenocarcinoma or affiliated genes

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Publications for Pancreatic Ductal Adenocarcinoma

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Articles related to Pancreatic Ductal Adenocarcinoma:

(show top 50)    (show all 632)
idTitleAuthorsYear
1
MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma. (25908274)
2015
2
Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells. (24297612)
2014
3
Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Pancreatic Ductal Adenocarcinoma at 3.0-T Magnetic Resonance: Correlation With Histopathology. (25340589)
2014
4
Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma. (25301264)
2014
5
miR-545 inhibited Pancreatic ductal adenocarcinoma growth by targeting RIG-I. (25315416)
2014
6
Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma. (23661430)
2013
7
Differential expression of RBM5 and KRAS in pancreatic ductal adenocarcinoma and their association with clinicopathological features. (23425895)
2013
8
Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma. (23260327)
2013
9
MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis. (23991015)
2013
10
Prognostic significance of autophagy-related protein expression in resected pancreatic ductal adenocarcinoma. (23429496)
2013
11
The predictive role of p16 deletion, p53 deletion, and polysomy 9 and 17 in pancreatic ductal adenocarcinoma. (22782330)
2013
12
Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma? (22436573)
2012
13
Clinical profiles and long-term outcomes of patients with pancreatic ductal adenocarcinoma and diabetes mellitus. (22423386)
2012
14
The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance. (22272725)
2012
15
Serum high mobility group box-1 is a powerful diagnostic and prognostic biomarker for pancreatic ductal adenocarcinoma. (22703527)
2012
16
Prognostic significance of PUMA in pancreatic ductal adenocarcinoma. (23321162)
2012
17
Can pharmacogenomics guide effective anticancer therapy in pancreatic ductal adenocarcinoma? (22838942)
2012
18
A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians. (21656579)
2012
19
Reduced expression of desmocollin 2 is an independent prognostic biomarker for shorter patients survival in pancreatic ductal adenocarcinoma. (21725043)
2011
20
Differentiating pancreatic ductal adenocarcinoma from pancreatic serous cystadenoma, mucinous cystadenoma, and a pseudocyst with detailed analysis of cystic features on CT scans: a preliminary study. (21430935)
2011
21
Clinicopathologic correlation of beclin-1 expression in pancreatic ductal adenocarcinoma. (21420796)
2011
22
MicroRNAs in pancreatic ductal adenocarcinoma. (21412491)
2011
23
Loss of heterozygosity status of D9S105 marker is associated with downregulation of KrA1ppel-like factor 4 expression in pancreatic ductal adenocarcinoma and pancreatic intraepithelial lesions. (21412023)
2011
24
Galectin-1 secreted by activated stellate cells in pancreatic ductal adenocarcinoma stroma promotes proliferation and invasion of pancreatic cancer cells: an in vitro study on the microenvironment of pancreatic ductal adenocarcinoma. (21747316)
2011
25
microRNA-10b: a new marker or the marker of pancreatic ductal adenocarcinoma? (21816909)
2011
26
Elevated transcript levels from the MDM2 P1 promoter and low p53 transcript levels are associated with poor prognosis in human pancreatic ductal adenocarcinoma. (21404460)
2011
27
Positive mobilization margins alone do not influence survival following pancreatico-duodenectomy for pancreatic ductal adenocarcinoma. (20485150)
2010
28
Inhibition of ankyrin-B expression reduces growth and invasion of human pancreatic ductal adenocarcinoma. (21042036)
2010
29
Ten years of experience with resection of left-sided pancreatic ductal adenocarcinoma: evolution and initial experience to a laparoscopic approach. (20054579)
2010
30
Novel drug targets based on association between inflammation and pancreatic ductal adenocarcinoma. (20601821)
2010
31
High TRAIL death receptor 4 and decoy receptor 2 expression correlates with significant cell death in pancreatic ductal adenocarcinoma patients. (18981952)
2009
32
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. (19208345)
2009
33
A combined, rational approach towards inhibition of the MEK-ERK and mTOR pathways in pancreatic ductal adenocarcinoma: promise or deja vu? (19783905)
2009
34
Screening for early pancreatic ductal adenocarcinoma: an urgent call! (19287101)
2009
35
Patterns of recurrence after curative resection of pancreatic ductal adenocarcinoma. (19131205)
2009
36
Preoperative resolution of jaundice following biliary stenting predicts more favourable early survival in resected pancreatic ductal adenocarcinoma. (18787902)
2008
37
Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution. (18724072)
2008
38
Synchronous autoimmune pancreatitis and infiltrating pancreatic ductal adenocarcinoma: case report and review of the literature. (18619645)
2008
39
Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. (18636150)
2008
40
Prognostic significance of immunohistochemical RhoA expression on survival in pancreatic ductal adenocarcinoma: a high-throughput analysis. (18495213)
2008
41
Evaluation of topoisomerase IIa expression in pancreatic ductal adenocarcinoma: a pilot study using chromogenic in situ hybridization and immunohistochemistry on tissue microarrays. (17449965)
2007
42
Simultaneous deregulation of p16 and cyclin D1 genes in pancreatic ductal adenocarcinoma: a combined immunohistochemistry and image analysis study based on tissue microarrays. (17600882)
2007
43
Cancer risk among the relatives of patients with pancreatic ductal adenocarcinoma. (17912010)
2007
44
GADD45alpha is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability. (16353139)
2006
45
Aberrant expression of a disintegrin and metalloproteinase 17/tumor necrosis factor-alpha converting enzyme increases the malignant potential in human pancreatic ductal adenocarcinoma. (16982746)
2006
46
Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma. (15814630)
2005
47
Prognostic value of VEGF in human pancreatic ductal adenocarcinoma. (15053037)
2004
48
Prognostic significance of maspin in pancreatic ductal adenocarcinoma. (15053038)
2004
49
Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma. (12402154)
2002
50
Foamy gland pattern of pancreatic ductal adenocarcinoma: a deceptively benign-appearing variant. (10757396)
2000

Variations for Pancreatic Ductal Adenocarcinoma

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Expression for genes affiliated with Pancreatic Ductal Adenocarcinoma

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LifeMap Discovery
Genes differentially expressed in tissues of Pancreatic Ductal Adenocarcinoma patients vs. healthy controls: 30 (show all 375)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1SYCNsyncollinPancreas-8.040.000
2GP2glycoprotein 2 (zymogen granule membrane)Pancreas-7.990.000
3ALBalbuminPancreas-7.950.000
4SERPINI2serpin peptidase inhibitor, clade I (pancpin), member 2Pancreas-7.950.000
5CELA2Bchymotrypsin-like elastase family, member 2BPancreas-7.740.000
6PNLIPRP1pancreatic lipase-related protein 1Pancreas-7.660.000
7PDIA2protein disulfide isomerase family A, member 2Pancreas-7.530.000
8C12orf39chromosome 12 open reading frame 39Pancreas-7.530.000
9CTRLchymotrypsin-likePancreas-7.520.000
10CELPcarboxyl ester lipase pseudogenePancreas-7.500.000
11CUZD1CUB and zona pellucida-like domains 1Pancreas-7.290.000
12AQP8aquaporin 8Pancreas-7.140.000
13CLPScolipase, pancreaticPancreas-6.990.000
14CPA2carboxypeptidase A2 (pancreatic)Pancreas-6.880.000
15CTRCchymotrypsin C (caldecrin)Pancreas-6.870.000
16PLA2G1Bphospholipase A2, group IB (pancreas)Pancreas-6.790.001
17CELA3Achymotrypsin-like elastase family, member 3APancreas-6.760.001
18GNMTglycine N-methyltransferasePancreas-6.740.000
19REG1Pregenerating islet-derived 1 pseudogenePancreas-6.710.000
20CELA3Bchymotrypsin-like elastase family, member 3BPancreas-6.660.001
21APOC1apolipoprotein C-IKidney+6.640.000
22CELcarboxyl ester lipasePancreas-6.630.001
23CPA1carboxypeptidase A1 (pancreatic)Pancreas-6.560.001
24TMEM52transmembrane protein 52Pancreas-6.400.000
25REG1Bregenerating islet-derived 1 betaPancreas-6.350.002
26GLS2glutaminase 2 (liver, mitochondrial)Pancreas-6.280.000
27KLK1kallikrein 1Pancreas-6.260.000
28REG3Gregenerating islet-derived 3 gammaPancreas-6.170.000
29SLC39A5solute carrier family 39 (zinc transporter), member 5Pancreas-6.090.000
30ERP27endoplasmic reticulum protein 27Pancreas-6.070.000
31PNLIPpancreatic lipasePancreas-5.940.004
32CBScystathionine-beta-synthasePancreas-5.850.000
33PNLIPRP2pancreatic lipase-related protein 2Pancreas-5.790.003
34PM20D1peptidase M20 domain containing 1Pancreas-5.760.000
35TNFAIP6tumor necrosis factor, alpha-induced protein 6Kidney+5.760.001
36FGL1fibrinogen-like 1Pancreas-5.720.000
37PAIP2Bpoly(A) binding protein interacting protein 2BPancreas-5.700.000
38SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2Pancreas-5.610.000
39TEX11testis expressed 11Pancreas-5.570.000
40TMED6transmembrane emp24 protein transport domain containing 6Pancreas-5.560.000
41BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3Pancreas-5.450.000
42CPB1carboxypeptidase B1 (tissue)Pancreas-5.340.006
43AKR7A3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)Pancreas-5.300.000
44REG3Aregenerating islet-derived 3 alphaPancreas-5.300.009
45CTRB2chymotrypsinogen B2Pancreas-5.290.005
46PRSS1protease, serine, 1 (trypsin 1)Pancreas-5.260.007
47SYBUsyntabulin (syntaxin-interacting)Pancreas-5.210.000
48RBPJLrecombination signal binding protein for immunoglobulin kappa J region-likePancreas-5.140.000
49PRSS3protease, serine, 3Pancreas-5.110.000
50CA4carbonic anhydrase IVPancreas-5.100.000
51MMP12matrix metallopeptidase 12 (macrophage elastase)Pancreas+5.060.000
52AADACarylacetamide deacetylasePancreas-5.040.000
53MGPmatrix Gla proteinPancreas+5.020.000
54MMP11matrix metallopeptidase 11 (stromelysin 3)Pancreas+5.000.000
55EPB41L4Berythrocyte membrane protein band 4.1 like 4BPancreas-4.990.000
56KYNUkynureninasePancreas+4.970.000
57OLFML2Bolfactomedin-like 2BPancreas+4.970.000
58SLC4A4solute carrier family 4 (sodium bicarbonate cotransporter), member 4Pancreas-4.970.000
59HOPXHOP homeoboxPancreas+4.960.000
60DUOX2dual oxidase 2Pancreas+4.960.000
61CALD1caldesmon 1Pancreas+4.950.000
62TNFAIP6tumor necrosis factor, alpha-induced protein 6Pancreas+4.950.000
63AZGP1alpha-2-glycoprotein 1, zinc-bindingPancreas-4.940.000
64TMPRSS4transmembrane protease, serine 4Pancreas+4.930.000
65HS3ST1heparan sulfate (glucosamine) 3-O-sulfotransferase 1Pancreas+4.930.000
66SLC30A2solute carrier family 30 (zinc transporter), member 2Pancreas-4.930.000
67ANO1anoctamin 1, calcium activated chloride channelPancreas+4.920.000
68CSTAcystatin A (stefin A)Pancreas+4.900.000
69AOX1aldehyde oxidase 1Pancreas-4.900.000
70ECT2epithelial cell transforming 2Pancreas+4.880.000
71KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)Pancreas+4.880.000
72BACE1beta-site APP-cleaving enzyme 1Pancreas-4.870.000
73CYP1B1cytochrome P450, family 1, subfamily B, polypeptide 1Pancreas+4.870.000
74TMEM97transmembrane protein 97Pancreas-4.870.000
75CXCL14chemokine (C-X-C motif) ligand 14Pancreas+4.860.000
76IL22RA1interleukin 22 receptor, alpha 1Pancreas-4.860.000
77HMCN1hemicentin 1Pancreas+4.850.000
78CXCR4chemokine (C-X-C motif) receptor 4Pancreas+4.850.000
79MMP1matrix metallopeptidase 1 (interstitial collagenase)Pancreas+4.850.001
80GAMTguanidinoacetate N-methyltransferasePancreas-4.840.000
81BCL2A1BCL2-related protein A1Pancreas+4.830.000
82TRHDEthyrotropin-releasing hormone degrading enzymePancreas-4.830.000
83AHNAK2AHNAK nucleoprotein 2Kidney+4.830.000
84GCNT3glucosaminyl (N-acetyl) transferase 3, mucin typePancreas+4.820.000
85CCKBRcholecystokinin B receptorPancreas-4.820.000
86AREGamphiregulinPancreas+4.820.000
87ZNF207zinc finger protein 207Pancreas+4.810.000
88SLC6A6solute carrier family 6 (neurotransmitter transporter), member 6Pancreas+4.810.000
89SPARCsecreted protein, acidic, cysteine-rich (osteonectin)Pancreas+4.800.000
90GABRPgamma-aminobutyric acid (GABA) A receptor, piPancreas+4.790.001
91HOMER2homer homolog 2 (Drosophila)Pancreas-4.790.000
92IFI44interferon-induced protein 44Pancreas+4.790.000
93PHLDA1pleckstrin homology-like domain, family A, member 1Pancreas+4.790.000
94SLC43A1solute carrier family 43 (amino acid system L transporter), member 1Pancreas-4.780.000
95TOP2Atopoisomerase (DNA) II alpha 170kDaKidney+4.780.001
96HLA-DPA1major histocompatibility complex, class II, DP alpha 1Pancreas+4.780.000
97SEL1Lsel-1 suppressor of lin-12-like (C. elegans)Pancreas-4.780.000
98PELI1pellino E3 ubiquitin protein ligase 1Pancreas+4.770.000
99ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)Pancreas+4.770.000
100STAT1signal transducer and activator of transcription 1, 91kDaPancreas+4.770.000
101TPSB2tryptase beta 2 (gene/pseudogene)Pancreas+4.760.000
102LAMA4laminin, alpha 4Pancreas+4.760.000
103LINC00339long intergenic non-protein coding RNA 339Pancreas-4.760.000
104HLA-DQB1major histocompatibility complex, class II, DQ beta 1Pancreas+4.760.000
105RGS1regulator of G-protein signaling 1Pancreas+4.730.000
106ITGBL1integrin, beta-like 1 (with EGF-like repeat domains)Pancreas+4.720.000
107ALDOBaldolase B, fructose-bisphosphatePancreas-4.720.000
108CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)Pancreas+4.720.000
109KRT19keratin 19Pancreas+4.710.000
110NREPneuronal regeneration related proteinPancreas+4.700.000
111SYTL2synaptotagmin-like 2Pancreas+4.700.000
112NQO1NAD(P)H dehydrogenase, quinone 1Pancreas+4.690.000
113GPX2glutathione peroxidase 2 (gastrointestinal)Pancreas+4.690.001
114GPNMBglycoprotein (transmembrane) nmbPancreas+4.690.000
115ITGB6integrin, beta 6Pancreas+4.670.000
116HPGDhydroxyprostaglandin dehydrogenase 15-(NAD)Pancreas+4.670.000
117TNFSF13Btumor necrosis factor (ligand) superfamily, member 13bPancreas+4.660.000
118MPEG1macrophage expressed 1Pancreas+4.660.000
119LAMC2laminin, gamma 2Pancreas+4.660.000
120CCL20chemokine (C-C motif) ligand 20Pancreas+4.660.000
121ZEB2zinc finger E-box binding homeobox 2Pancreas+4.660.000
122LAMA3laminin, alpha 3Pancreas+4.630.000
123JMJD1Cjumonji domain containing 1CPancreas+4.630.000
124DEFB1defensin, beta 1Pancreas-4.630.000
125EPSTI1epithelial stromal interaction 1 (breast)Pancreas+4.620.000
126CD109CD109 moleculePancreas+4.610.000
127TFPI2tissue factor pathway inhibitor 2Kidney+4.590.000
128LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)Pancreas+4.590.000
129ARSEarylsulfatase E (chondrodysplasia punctata 1)Pancreas-4.580.000
130CTSKcathepsin KPancreas+4.570.000
131CD52CD52 moleculePancreas+4.570.000
132REG1Aregenerating islet-derived 1 alphaPancreas-4.560.016
133TGFBR1transforming growth factor, beta receptor 1Pancreas+4.550.000
134CASP1caspase 1, apoptosis-related cysteine peptidasePancreas+4.550.000
135CCDC80coiled-coil domain containing 80Pancreas+4.550.000
136CST1cystatin SNPancreas+4.530.000
137FBN1fibrillin 1Pancreas+4.520.000
138SLFN13schlafen family member 13Kidney+4.520.000
139DPEP1dipeptidase 1 (renal)Pancreas-4.500.000
140GPR183G protein-coupled receptor 183Pancreas+4.500.000
141IGLimmunoglobulin lambda locusPancreas+4.490.000
142CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)Kidney+4.490.029
143PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)Pancreas+4.490.001
144GLT8D2glycosyltransferase 8 domain containing 2Pancreas+4.460.000
145EGR2early growth response 2Pancreas+4.460.000
146VCANversicanKidney+4.450.003
147KLK10kallikrein-related peptidase 10Pancreas+4.440.002
148THBS2thrombospondin 2Pancreas+4.440.000
149ALOX5arachidonate 5-lipoxygenaseKidney+4.430.000
150CAPN8calpain 8Pancreas+4.430.000
151NR5A2nuclear receptor subfamily 5, group A, member 2Pancreas-4.430.000
152PDLIM3PDZ and LIM domain 3Pancreas+4.430.000
153ANTXR1anthrax toxin receptor 1Pancreas+4.420.000
154ANPEPalanyl (membrane) aminopeptidasePancreas-4.420.002
155ADCY7adenylate cyclase 7Pancreas+4.410.000
156OAS12'-5'-oligoadenylate synthetase 1, 40/46kDaPancreas+4.400.000
157PDK4pyruvate dehydrogenase kinase, isozyme 4Pancreas-4.390.000
158COCHcochlinPancreas-4.380.000
159GUCA1Cguanylate cyclase activator 1CPancreas-4.380.000
160P2RX1purinergic receptor P2X, ligand-gated ion channel, 1Pancreas-4.370.000
161FAM26Ffamily with sequence similarity 26, member FPancreas+4.370.000
162TAGAPT-cell activation RhoGTPase activating proteinPancreas+4.360.000
163IGKV4-1immunoglobulin kappa variable 4-1Pancreas+4.360.000
164PRDM1PR domain containing 1, with ZNF domainPancreas+4.360.000
165EVI2Becotropic viral integration site 2BPancreas+4.350.000
166LOC284454uncharacterized LOC284454Pancreas+4.340.000
167C5complement component 5Pancreas-4.340.000
168TRIM14tripartite motif containing 14Pancreas+4.340.000
169CEMIPcell migration inducing protein, hyaluronan bindingPancreas+4.330.000
170OSBPL3oxysterol binding protein-like 3Pancreas+4.330.000
171LCN2lipocalin 2Kidney+4.330.000
172KIAA1324KIAA1324Pancreas-4.320.000
173HNRNPU-AS1HNRNPU antisense RNA 1Pancreas+4.320.000
174GPR34G protein-coupled receptor 34Pancreas+4.310.000
175ERO1LBERO1-like beta (S. cerevisiae)Pancreas-4.310.000
176IL8interleukin 8Pancreas+4.300.000
177C19orf33chromosome 19 open reading frame 33Pancreas+4.300.000
178C15orf48chromosome 15 open reading frame 48Pancreas+4.300.000
179CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)Pancreas+4.290.000
180IL18interleukin 18 (interferon-gamma-inducing factor)Pancreas+4.290.000
181IGFBP3insulin-like growth factor binding protein 3Pancreas+4.290.001
182NOX4NADPH oxidase 4Pancreas+4.290.000
183KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16Pancreas-4.290.000
184SERPINB5serpin peptidase inhibitor, clade B (ovalbumin), member 5Pancreas+4.280.000
185IL1RNinterleukin 1 receptor antagonistPancreas+4.280.000
186GPR137BG protein-coupled receptor 137BPancreas+4.280.000
187CA12carbonic anhydrase XIIPancreas-4.280.000
188FPR3formyl peptide receptor 3Pancreas+4.270.000
189HSPA6heat shock 70kDa protein 6 (HSP70B')Pancreas+4.270.000
190RUNX1runt-related transcription factor 1Pancreas+4.270.000
191DPY19L1dpy-19-like 1 (C. elegans)Pancreas+4.270.000
192HPNhepsinPancreas-4.270.000
193CD69CD69 moleculePancreas+4.260.000
194GBP3guanylate binding protein 3Pancreas+4.250.000
195LRRC20leucine rich repeat containing 20Kidney+4.250.000
196CXCL3chemokine (C-X-C motif) ligand 3Pancreas+4.240.000
197COA1cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)Pancreas+4.240.000
198C3complement component 3Kidney+4.240.001
199NCF2neutrophil cytosolic factor 2Pancreas+4.240.000
200DLEU2deleted in lymphocytic leukemia 2 (non-protein coding)Pancreas+4.240.000
201LAMB3laminin, beta 3Pancreas+4.240.000
202ADAM28ADAM metallopeptidase domain 28Pancreas+4.230.000
203PSAT1phosphoserine aminotransferase 1Pancreas-4.230.000
204CHRM3cholinergic receptor, muscarinic 3Pancreas-4.220.000
205SLC38A5solute carrier family 38, member 5Pancreas-4.210.000
206OLR1oxidized low density lipoprotein (lectin-like) receptor 1Pancreas+4.210.000
207CMAHPcytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogenePancreas+4.210.000
208GPRC5AG protein-coupled receptor, class C, group 5, member APancreas+4.210.000
209AHNAK2AHNAK nucleoprotein 2Pancreas+4.200.000
210CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)Pancreas+4.200.000
211OSBPL10oxysterol binding protein-like 10Pancreas+4.200.000
212SH3KBP1SH3-domain kinase binding protein 1Pancreas+4.190.000
213IL2RGinterleukin 2 receptor, gammaPancreas+4.190.000
214ACSL5acyl-CoA synthetase long-chain family member 5Pancreas+4.180.000
215KRT17keratin 17Pancreas+4.180.000
216IGHMimmunoglobulin heavy constant muPancreas+4.170.000
217SDR16C5short chain dehydrogenase/reductase family 16C, member 5Pancreas+4.170.001
218CD86CD86 moleculePancreas+4.170.000
219AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)Pancreas+4.170.003
220BIRC3baculoviral IAP repeat containing 3Pancreas+4.170.000
221SLC2A3solute carrier family 2 (facilitated glucose transporter), member 3Pancreas+4.170.000
222TRIOtrio Rho guanine nucleotide exchange factorPancreas+4.170.000
223TPSAB1tryptase alpha/beta 1Pancreas+4.160.000
224FAM150Bfamily with sequence similarity 150, member BPancreas-4.160.000
225GIMAP2GTPase, IMAP family member 2Pancreas+4.150.000
226PLAURplasminogen activator, urokinase receptorPancreas+4.140.000
227LOXlysyl oxidasePancreas+4.140.000
228MS4A6Amembrane-spanning 4-domains, subfamily A, member 6APancreas+4.140.000
229CTSScathepsin SPancreas+4.130.000
230PLXNC1plexin C1Pancreas+4.120.000
231PHLDA2pleckstrin homology-like domain, family A, member 2Pancreas+4.110.000
232RBP1retinol binding protein 1, cellularPancreas-4.110.000
233GZMAgranzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)Pancreas+4.110.000
234POU2AF1POU class 2 associating factor 1Pancreas+4.100.000
235OGNosteoglycinPancreas+4.100.000
236DKK3dickkopf WNT signaling pathway inhibitor 3Pancreas+4.100.000
237FCGR2BFc fragment of IgG, low affinity IIb, receptor (CD32)Pancreas+4.100.000
238RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated)Pancreas+4.090.000
239SPON1spondin 1, extracellular matrix proteinPancreas+4.080.000
240ACADLacyl-CoA dehydrogenase, long chainPancreas-4.080.000
241LOXL1lysyl oxidase-like 1Pancreas+4.080.000
242CD74CD74 molecule, major histocompatibility complex, class II invariant chainPancreas+4.070.000
243CLEC7AC-type lectin domain family 7, member APancreas+4.060.000
244REG4regenerating islet-derived family, member 4Pancreas+4.060.038
245CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)Pancreas+4.060.000
246LACC1laccase (multicopper oxidoreductase) domain containing 1Pancreas+4.060.000
247UHRF1BP1LUHRF1 binding protein 1-likePancreas+4.060.000
248ALG13ALG13, UDP-N-acetylglucosaminyltransferase subunitPancreas+4.050.000
249ZBTB16zinc finger and BTB domain containing 16Pancreas-4.020.000
250SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1Pancreas-4.000.000
251ABHD11abhydrolase domain containing 11Kidney+4.000.000
252HK2hexokinase 2Kidney+3.980.000
253SEC16BSEC16 homolog B (S. cerevisiae)Kidney+3.980.000
254H19H19, imprinted maternally expressed transcript (non-protein coding)Pancreas-3.980.010
255ITIH4inter-alpha-trypsin inhibitor heavy chain family, member 4Pancreas-3.960.000
256LGALS2lectin, galactoside-binding, soluble, 2Pancreas-3.940.001
257PRSS2protease, serine, 2 (trypsin 2)Pancreas-3.930.026
258ACSM3acyl-CoA synthetase medium-chain family member 3Pancreas-3.920.000
259KIF1Akinesin family member 1APancreas-3.920.000
260ABCB4ATP-binding cassette, sub-family B (MDR/TAP), member 4Kidney+3.910.002
261INSRinsulin receptorPancreas-3.890.000
262PDCD4programmed cell death 4 (neoplastic transformation inhibitor)Pancreas-3.880.000
263SERPINA4serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4Pancreas-3.870.000
264C6complement component 6Pancreas-3.840.000
265NRTNneurturinKidney+3.840.002
266KCNK3potassium channel, subfamily K, member 3Pancreas-3.830.000
267GPT2glutamic pyruvate transaminase (alanine aminotransferase) 2Pancreas-3.810.000
268DNM1dynamin 1Kidney+3.810.000
269COMTD1catechol-O-methyltransferase domain containing 1Pancreas-3.810.000
270LOC100289026putative uncharacterized protein FLJ00310-likeKidney+3.800.002
271HOXA1homeobox A1Kidney+3.800.000
272F8coagulation factor VIII, procoagulant componentPancreas-3.790.000
273PGBD5piggyBac transposable element derived 5Pancreas-3.790.000
274SFRP5secreted frizzled-related protein 5Pancreas-3.790.000
275LEFTY1left-right determination factor 1Pancreas-3.770.005
276LYPD1LY6/PLAUR domain containing 1Kidney+3.760.019
277KIRREL2kin of IRRE like 2 (Drosophila)Pancreas-3.760.000
278C3orf67chromosome 3 open reading frame 67Kidney+3.760.000
279TREM2triggering receptor expressed on myeloid cells 2Kidney+3.760.000
280TM7SF2transmembrane 7 superfamily member 2Pancreas-3.760.000
281DAPL1death associated protein-like 1Pancreas-3.750.000
282IMPA2inositol(myo)-1(or 4)-monophosphatase 2Pancreas-3.750.000
283FXYD2FXYD domain containing ion transport regulator 2Pancreas-3.740.000
284PLXNA2plexin A2Pancreas-3.730.000
285NPTX2neuronal pentraxin IIPancreas-3.710.000
286SSFA2sperm specific antigen 2Pancreas-3.700.000
287HAVCR1hepatitis A virus cellular receptor 1Kidney+3.670.000
288SLC25A15solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15Pancreas-3.660.000
289NTRK2neurotrophic tyrosine kinase, receptor, type 2Pancreas-3.650.000
290DLK1delta-like 1 homolog (Drosophila)Pancreas-3.650.001
291FABP4fatty acid binding protein 4, adipocytePancreas-3.630.008
292HTRA4HtrA serine peptidase 4Kidney+3.620.002
293LOC553137uncharacterized LOC553137Pancreas-3.610.000
294CXCL6chemokine (C-X-C motif) ligand 6Kidney+3.610.036
295ECHDC3enoyl CoA hydratase domain containing 3Pancreas-3.610.000
296GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)Pancreas-3.600.000
297PHGDHphosphoglycerate dehydrogenasePancreas-3.580.000
298F12coagulation factor XII (Hageman factor)Kidney+3.570.004
299SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2Pancreas-3.560.000
300CRYBA2crystallin, beta A2Pancreas-3.560.000
301BCANbrevicanKidney+3.560.001
302CCND2cyclin D2Kidney+3.550.000
303KCNJ8potassium inwardly-rectifying channel, subfamily J, member 8Pancreas-3.540.000
304HSD17B8hydroxysteroid (17-beta) dehydrogenase 8Pancreas-3.530.000
305SLC1A4solute carrier family 1 (glutamate/neutral amino acid transporter), member 4Pancreas-3.520.000
306LRRN4leucine rich repeat neuronal 4Kidney+3.520.000
307C15orf48chromosome 15 open reading frame 48Kidney+3.500.015
308SLC39A8solute carrier family 39 (zinc transporter), member 8Pancreas-3.500.000
309BRIP1BRCA1 interacting protein C-terminal helicase 1Kidney+3.500.001
310NAV3neuron navigator 3Kidney+3.480.007
311FOXA3forkhead box A3Pancreas-3.460.000
312FAM3Bfamily with sequence similarity 3, member BPancreas-3.430.003
313SERPINA5serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5Pancreas-3.420.001
314TPX2TPX2, microtubule-associatedKidney+3.420.013
315NNMTnicotinamide N-methyltransferaseKidney+3.420.004
316SERPINA3serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3Pancreas-3.400.007
317SCG5secretogranin V (7B2 protein)Kidney+3.380.020
318HS3ST1heparan sulfate (glucosamine) 3-O-sulfotransferase 1Kidney+3.370.004
319S100A12S100 calcium binding protein A12Pancreas-3.370.000
320C19orf48chromosome 19 open reading frame 48Pancreas-3.350.000
321HIST1H2AGhistone cluster 1, H2agKidney+3.350.024
322SPAG4sperm associated antigen 4Pancreas-3.340.000
323PARM1prostate androgen-regulated mucin-like protein 1Pancreas-3.340.000
324RHOBTB3Rho-related BTB domain containing 3Pancreas-3.330.000
325C1orf186chromosome 1 open reading frame 186Kidney+3.320.001
326CLDN10claudin 10Pancreas-3.300.025
327RPH3ALrabphilin 3A-like (without C2 domains)Pancreas-3.300.000
328MTUS2microtubule associated tumor suppressor candidate 2Pancreas-3.290.000
329CTNND2catenin (cadherin-associated protein), delta 2Pancreas-3.290.000
330BSPRYB-box and SPRY domain containingPancreas-3.290.000
331LINC00261long intergenic non-protein coding RNA 261Pancreas-3.290.000
332SSTsomatostatinPancreas-3.260.033
333RAB3DRAB3D, member RAS oncogene familyPancreas-3.250.000
334MNX1motor neuron and pancreas homeobox 1Kidney+3.240.000
335BTG2BTG family, member 2Pancreas-3.240.000
336ONECUT2one cut homeobox 2Kidney+3.230.013
337NLE1notchless homolog 1 (Drosophila)Pancreas-3.230.000
338CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)Pancreas-3.210.016
339DCDC2doublecortin domain containing 2Pancreas-3.200.001
340CD86CD86 moleculeKidney+3.200.001
341TTKTTK protein kinaseKidney+3.190.012
342ANXA9annexin A9Pancreas-3.180.000
343TPST2tyrosylprotein sulfotransferase 2Pancreas-3.170.000
344USTuronyl-2-sulfotransferasePancreas-3.170.000
345MSRB1methionine sulfoxide reductase B1Pancreas-3.170.000
346NEK2NIMA-related kinase 2Kidney+3.160.033
347MAOAmonoamine oxidase APancreas-3.150.000
348KIF20Akinesin family member 20AKidney+3.140.027
349TEN1TEN1 CST complex subunitKidney+3.140.013
350PAK3p21 protein (Cdc42/Rac)-activated kinase 3Pancreas-3.130.000
351TLCD2TLC domain containing 2Kidney+3.130.007
352PDE8Bphosphodiesterase 8BPancreas-3.120.000
353TMEM125transmembrane protein 125Pancreas-3.120.000
354CLDN3claudin 3Pancreas-3.120.011
355C21orf2chromosome 21 open reading frame 2Pancreas-3.120.000
356P4HBprolyl 4-hydroxylase, beta polypeptidePancreas-3.120.000
357SLC38A4solute carrier family 38, member 4Pancreas-3.110.000
358SYTL1synaptotagmin-like 1Pancreas-3.110.000
359LOC340340uncharacterized LOC340340Kidney+3.100.023
360VEPH1ventricular zone expressed PH domain-containing 1Pancreas-3.100.000
361STXBP6syntaxin binding protein 6 (amisyn)Pancreas-3.090.000
362TPM1tropomyosin 1 (alpha)Pancreas-3.090.000
363PIFOprimary cilia formationPancreas-3.090.000
364KLHDC10kelch domain containing 10Pancreas-3.080.000
365SLC3A1solute carrier family 3 (amino acid transporter heavy chain), member 1Pancreas-3.080.034
366DHRS12dehydrogenase/reductase (SDR family) member 12Pancreas-3.080.000
367UNC5Aunc-5 homolog A (C. elegans)Kidney+3.070.045
368SLC37A4solute carrier family 37 (glucose-6-phosphate transporter), member 4Pancreas-3.070.000
369ARRB1arrestin, beta 1Pancreas-3.070.000
370FANCIFanconi anemia, complementation group IKidney+3.060.011
371CDHR1cadherin-related family member 1Kidney+3.060.026
372APLP1amyloid beta (A4) precursor-like protein 1Pancreas-3.020.000
373MUC15mucin 15, cell surface associatedPancreas-3.020.000
374STC2stanniocalcin 2Pancreas-3.020.000
375BEX5brain expressed, X-linked 5Pancreas-3.010.001

Search GEO for disease gene expression data for Pancreatic Ductal Adenocarcinoma.

Pathways for genes affiliated with Pancreatic Ductal Adenocarcinoma

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Pathways related to Pancreatic Ductal Adenocarcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4MIR21, MIR181B1
28.6MIR21, MIR10B, MIR224, MIR181B1

Compounds for genes affiliated with Pancreatic Ductal Adenocarcinoma

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GO Terms for genes affiliated with Pancreatic Ductal Adenocarcinoma

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Products for genes affiliated with Pancreatic Ductal Adenocarcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Pancreatic Ductal Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet