MCID: PNC041
MIFTS: 35

Pancreatic Ductal Adenocarcinoma malady

Cancer diseases, Endocrine diseases categories

Summaries for Pancreatic Ductal Adenocarcinoma

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Disease Ontology:9 A pancreas adenocarcinoma that derives from pancreatic duct cells.

MalaCards based summary: Pancreatic Ductal Adenocarcinoma, also known as ductal adenocarcinoma of the pancreas, is related to adenocarcinoma and pancreatitis. An important gene associated with Pancreatic Ductal Adenocarcinoma is MIR196A2 (microRNA 196a-2), and among its related pathways are miRNAs involved in DDR and MicroRNAs in cancer. Affiliated tissues include pancreas, lymph node and liver.

Aliases & Classifications for Pancreatic Ductal Adenocarcinoma

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Pancreatic Ductal Adenocarcinoma, Aliases & Descriptions:

Name: Pancreatic Ductal Adenocarcinoma 31 9 11 61
 
Ductal Adenocarcinoma of the Pancreas 9 61


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Endocrine diseases


External Ids:

Disease Ontology9 DOID:3498
NCIt39 C9120

Related Diseases for Pancreatic Ductal Adenocarcinoma

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Graphical network of the top 20 diseases related to Pancreatic Ductal Adenocarcinoma:



Diseases related to pancreatic ductal adenocarcinoma

Symptoms for Pancreatic Ductal Adenocarcinoma

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Drugs & Therapeutics for Pancreatic Ductal Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Pancreatic Ductal Adenocarcinoma

Search NIH Clinical Center for Pancreatic Ductal Adenocarcinoma

Genetic Tests for Pancreatic Ductal Adenocarcinoma

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Anatomical Context for Pancreatic Ductal Adenocarcinoma

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MalaCards organs/tissues related to Pancreatic Ductal Adenocarcinoma:

32
Pancreas, Lymph node, Liver, Testes, Neutrophil, T cells, Smooth muscle, Skeletal muscle, Colon, Breast, Monocytes, Endothelial

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Pancreatic Ductal Adenocarcinoma:
id TissueAnatomical CompartmentCell Relevance
1 PancreasPancreatic Ducts  Affected by disease

Animal Models for Pancreatic Ductal Adenocarcinoma or affiliated genes

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Publications for Pancreatic Ductal Adenocarcinoma

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Articles related to Pancreatic Ductal Adenocarcinoma:

(show top 50)    (show all 611)
idTitleAuthorsYear
1
Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells. (24297612)
2014
2
Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Pancreatic Ductal Adenocarcinoma at 3.0-T Magnetic Resonance: Correlation With Histopathology. (25340589)
2014
3
Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma. (25301264)
2014
4
miR-545 inhibited Pancreatic ductal adenocarcinoma growth by targeting RIG-I. (25315416)
2014
5
Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma. (23661430)
2013
6
Differential expression of RBM5 and KRAS in pancreatic ductal adenocarcinoma and their association with clinicopathological features. (23425895)
2013
7
Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma. (23260327)
2013
8
MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis. (23991015)
2013
9
Prognostic significance of autophagy-related protein expression in resected pancreatic ductal adenocarcinoma. (23429496)
2013
10
The predictive role of p16 deletion, p53 deletion, and polysomy 9 and 17 in pancreatic ductal adenocarcinoma. (22782330)
2013
11
Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma? (22436573)
2012
12
Clinical profiles and long-term outcomes of patients with pancreatic ductal adenocarcinoma and diabetes mellitus. (22423386)
2012
13
The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance. (22272725)
2012
14
Serum high mobility group box-1 is a powerful diagnostic and prognostic biomarker for pancreatic ductal adenocarcinoma. (22703527)
2012
15
Prognostic significance of PUMA in pancreatic ductal adenocarcinoma. (23321162)
2012
16
Can pharmacogenomics guide effective anticancer therapy in pancreatic ductal adenocarcinoma? (22838942)
2012
17
A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians. (21656579)
2012
18
Reduced expression of desmocollin 2 is an independent prognostic biomarker for shorter patients survival in pancreatic ductal adenocarcinoma. (21725043)
2011
19
Differentiating pancreatic ductal adenocarcinoma from pancreatic serous cystadenoma, mucinous cystadenoma, and a pseudocyst with detailed analysis of cystic features on CT scans: a preliminary study. (21430935)
2011
20
Clinicopathologic correlation of beclin-1 expression in pancreatic ductal adenocarcinoma. (21420796)
2011
21
MicroRNAs in pancreatic ductal adenocarcinoma. (21412491)
2011
22
Loss of heterozygosity status of D9S105 marker is associated with downregulation of KrA1ppel-like factor 4 expression in pancreatic ductal adenocarcinoma and pancreatic intraepithelial lesions. (21412023)
2011
23
Galectin-1 secreted by activated stellate cells in pancreatic ductal adenocarcinoma stroma promotes proliferation and invasion of pancreatic cancer cells: an in vitro study on the microenvironment of pancreatic ductal adenocarcinoma. (21747316)
2011
24
microRNA-10b: a new marker or the marker of pancreatic ductal adenocarcinoma? (21816909)
2011
25
Elevated transcript levels from the MDM2 P1 promoter and low p53 transcript levels are associated with poor prognosis in human pancreatic ductal adenocarcinoma. (21404460)
2011
26
Positive mobilization margins alone do not influence survival following pancreatico-duodenectomy for pancreatic ductal adenocarcinoma. (20485150)
2010
27
Inhibition of ankyrin-B expression reduces growth and invasion of human pancreatic ductal adenocarcinoma. (21042036)
2010
28
Ten years of experience with resection of left-sided pancreatic ductal adenocarcinoma: evolution and initial experience to a laparoscopic approach. (20054579)
2010
29
Novel drug targets based on association between inflammation and pancreatic ductal adenocarcinoma. (20601821)
2010
30
High TRAIL death receptor 4 and decoy receptor 2 expression correlates with significant cell death in pancreatic ductal adenocarcinoma patients. (18981952)
2009
31
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. (19208345)
2009
32
A combined, rational approach towards inhibition of the MEK-ERK and mTOR pathways in pancreatic ductal adenocarcinoma: promise or deja vu? (19783905)
2009
33
Screening for early pancreatic ductal adenocarcinoma: an urgent call! (19287101)
2009
34
Patterns of recurrence after curative resection of pancreatic ductal adenocarcinoma. (19131205)
2009
35
Lifetime history of alcohol consumption and K-ras mutations in pancreatic ductal adenocarcinoma. (19326463)
2009
36
Preoperative resolution of jaundice following biliary stenting predicts more favourable early survival in resected pancreatic ductal adenocarcinoma. (18787902)
2008
37
Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution. (18724072)
2008
38
Synchronous autoimmune pancreatitis and infiltrating pancreatic ductal adenocarcinoma: case report and review of the literature. (18619645)
2008
39
Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. (18636150)
2008
40
Prognostic significance of immunohistochemical RhoA expression on survival in pancreatic ductal adenocarcinoma: a high-throughput analysis. (18495213)
2008
41
Evaluation of topoisomerase IIa expression in pancreatic ductal adenocarcinoma: a pilot study using chromogenic in situ hybridization and immunohistochemistry on tissue microarrays. (17449965)
2007
42
Simultaneous deregulation of p16 and cyclin D1 genes in pancreatic ductal adenocarcinoma: a combined immunohistochemistry and image analysis study based on tissue microarrays. (17600882)
2007
43
Cancer risk among the relatives of patients with pancreatic ductal adenocarcinoma. (17912010)
2007
44
GADD45alpha is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability. (16353139)
2006
45
Aberrant expression of a disintegrin and metalloproteinase 17/tumor necrosis factor-alpha converting enzyme increases the malignant potential in human pancreatic ductal adenocarcinoma. (16982746)
2006
46
Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma. (15814630)
2005
47
Prognostic value of VEGF in human pancreatic ductal adenocarcinoma. (15053037)
2004
48
Prognostic significance of maspin in pancreatic ductal adenocarcinoma. (15053038)
2004
49
Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma. (12402154)
2002
50
Foamy gland pattern of pancreatic ductal adenocarcinoma: a deceptively benign-appearing variant. (10757396)
2000

Variations for Pancreatic Ductal Adenocarcinoma

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Expression for genes affiliated with Pancreatic Ductal Adenocarcinoma

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LifeMap Discovery
Genes differentially expressed in tissues of Pancreatic Ductal Adenocarcinoma patients vs. healthy controls: 31 (show all 400)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1SYCNsyncollinPancreas-8.040.000
2GP2glycoprotein 2 (zymogen granule membrane)Pancreas-7.990.000
3ALBalbuminPancreas-7.950.000
4SERPINI2serpin peptidase inhibitor, clade I (pancpin), member 2Pancreas-7.950.000
5CELA2Bchymotrypsin-like elastase family, member 2BPancreas-7.740.000
6PNLIPRP1pancreatic lipase-related protein 1Pancreas-7.660.000
7PDIA2protein disulfide isomerase family A, member 2Pancreas-7.530.000
8C12orf39chromosome 12 open reading frame 39Pancreas-7.530.000
9CTRLchymotrypsin-likePancreas-7.520.000
10COL10A1collagen, type X, alpha 1Pancreas+7.520.000
11CELPcarboxyl ester lipase pseudogenePancreas-7.500.000
12COL5A1collagen, type V, alpha 1Pancreas+7.460.000
13SULF1sulfatase 1Pancreas+7.380.000
14CUZD1CUB and zona pellucida-like domains 1Pancreas-7.290.000
15POSTNperiostin, osteoblast specific factorPancreas+7.240.000
16COL1A1collagen, type I, alpha 1Pancreas+7.170.000
17AQP8aquaporin 8Pancreas-7.140.000
18CEACAM5carcinoembryonic antigen-related cell adhesion molecule 5Pancreas+7.100.000
19COL11A1collagen, type XI, alpha 1Pancreas+7.000.000
20CLPScolipase, pancreaticPancreas-6.990.000
21INHBAinhibin, beta APancreas+6.950.000
22CPA2carboxypeptidase A2 (pancreatic)Pancreas-6.880.000
23CTRCchymotrypsin C (caldecrin)Pancreas-6.870.000
24CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)Pancreas+6.860.000
25PLA2G1Bphospholipase A2, group IB (pancreas)Pancreas-6.790.001
26COL3A1collagen, type III, alpha 1Pancreas+6.780.000
27SFRP4secreted frizzled-related protein 4Pancreas+6.760.000
28CELA3Achymotrypsin-like elastase family, member 3APancreas-6.760.001
29GNMTglycine N-methyltransferasePancreas-6.740.000
30COL1A2collagen, type I, alpha 2Pancreas+6.720.000
31REG1Pregenerating islet-derived 1 pseudogenePancreas-6.710.000
32S100PS100 calcium binding protein PPancreas+6.670.000
33CELA3Bchymotrypsin-like elastase family, member 3BPancreas-6.660.001
34CELcarboxyl ester lipasePancreas-6.630.001
35CTHRC1collagen triple helix repeat containing 1Pancreas+6.600.000
36CPA1carboxypeptidase A1 (pancreatic)Pancreas-6.560.001
37VCANversicanPancreas+6.510.000
38TMEM52transmembrane protein 52Pancreas-6.400.000
39REG1Bregenerating islet-derived 1 betaPancreas-6.350.002
40CTSEcathepsin EPancreas+6.300.000
41GLS2glutaminase 2 (liver, mitochondrial)Pancreas-6.280.000
42KLK1kallikrein 1Pancreas-6.260.000
43GJB2gap junction protein, beta 2, 26kDaPancreas+6.240.000
44REG3Gregenerating islet-derived 3 gammaPancreas-6.170.000
45PLAUplasminogen activator, urokinasePancreas+6.150.000
46COL5A2collagen, type V, alpha 2Pancreas+6.130.000
47SLC39A5solute carrier family 39 (zinc transporter), member 5Pancreas-6.090.000
48ERP27endoplasmic reticulum protein 27Pancreas-6.070.000
49SEMA3Csema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3CPancreas+6.000.000
50PNLIPpancreatic lipasePancreas-5.940.004
51CXCL5chemokine (C-X-C motif) ligand 5Pancreas+5.920.000
52CBScystathionine-beta-synthasePancreas-5.850.000
53CLDN18claudin 18Pancreas+5.790.001
54PNLIPRP2pancreatic lipase-related protein 2Pancreas-5.790.003
55PM20D1peptidase M20 domain containing 1Pancreas-5.760.000
56FGL1fibrinogen-like 1Pancreas-5.720.000
57XAF1XIAP associated factor 1Pancreas+5.720.000
58NTMneurotriminPancreas+5.710.000
59PAIP2Bpoly(A) binding protein interacting protein 2BPancreas-5.700.000
60CDH11cadherin 11, type 2, OB-cadherin (osteoblast)Pancreas+5.670.000
61SAMSN1SAM domain, SH3 domain and nuclear localization signals 1Pancreas+5.660.000
62SFNstratifinPancreas+5.650.000
63MFAP5microfibrillar associated protein 5Pancreas+5.650.000
64SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 2Pancreas-5.610.000
65TEX11testis expressed 11Pancreas-5.570.000
66TMED6transmembrane emp24 protein transport domain containing 6Pancreas-5.560.000
67EDNRAendothelin receptor type APancreas+5.550.000
68ASPNasporinPancreas+5.530.000
69BNIP3BCL2/adenovirus E1B 19kDa interacting protein 3Pancreas-5.450.000
70RUNX2runt-related transcription factor 2Pancreas+5.450.000
71SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1Pancreas+5.420.000
72LEF1lymphoid enhancer-binding factor 1Pancreas+5.410.000
73COL12A1collagen, type XII, alpha 1Pancreas+5.410.000
74PCDH7protocadherin 7Pancreas+5.390.000
75IFI44Linterferon-induced protein 44-likePancreas+5.380.000
76FAPfibroblast activation protein, alphaPancreas+5.380.000
77LY75lymphocyte antigen 75Pancreas+5.380.000
78PTPRCprotein tyrosine phosphatase, receptor type, CPancreas+5.360.000
79SFRP2secreted frizzled-related protein 2Pancreas+5.360.000
80CPB1carboxypeptidase B1 (tissue)Pancreas-5.340.006
81AKR7A3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)Pancreas-5.300.000
82REG3Aregenerating islet-derived 3 alphaPancreas-5.300.009
83CTRB2chymotrypsinogen B2Pancreas-5.290.005
84GBP1guanylate binding protein 1, interferon-induciblePancreas+5.280.000
85PRSS1protease, serine, 1 (trypsin 1)Pancreas-5.260.007
86GREM1gremlin 1, DAN family BMP antagonistPancreas+5.220.000
87SYBUsyntabulin (syntaxin-interacting)Pancreas-5.210.000
88THY1Thy-1 cell surface antigenPancreas+5.210.000
89VNN1vanin 1Pancreas+5.200.000
90FNDC1fibronectin type III domain containing 1Pancreas+5.170.000
91HEPHhephaestinPancreas+5.160.000
92SLC6A14solute carrier family 6 (amino acid transporter), member 14Pancreas+5.150.000
93RBPJLrecombination signal binding protein for immunoglobulin kappa J region-likePancreas-5.140.000
94KLF5Kruppel-like factor 5 (intestinal)Pancreas+5.120.000
95TRIM29tripartite motif containing 29Pancreas+5.110.000
96PRSS3protease, serine, 3Pancreas-5.110.000
97CA4carbonic anhydrase IVPancreas-5.100.000
98SLC20A1solute carrier family 20 (phosphate transporter), member 1Pancreas+5.100.000
99PLAC8placenta-specific 8Pancreas+5.090.000
100MMP12matrix metallopeptidase 12 (macrophage elastase)Pancreas+5.060.000
101AADACarylacetamide deacetylasePancreas-5.040.000
102MGPmatrix Gla proteinPancreas+5.020.000
103MMP11matrix metallopeptidase 11 (stromelysin 3)Pancreas+5.000.000
104EPB41L4Berythrocyte membrane protein band 4.1 like 4BPancreas-4.990.000
105KYNUkynureninasePancreas+4.970.000
106OLFML2Bolfactomedin-like 2BPancreas+4.970.000
107SLC4A4solute carrier family 4 (sodium bicarbonate cotransporter), member 4Pancreas-4.970.000
108HOPXHOP homeoboxPancreas+4.960.000
109DUOX2dual oxidase 2Pancreas+4.960.000
110CALD1caldesmon 1Pancreas+4.950.000
111TNFAIP6tumor necrosis factor, alpha-induced protein 6Pancreas+4.950.000
112AZGP1alpha-2-glycoprotein 1, zinc-bindingPancreas-4.940.000
113TMPRSS4transmembrane protease, serine 4Pancreas+4.930.000
114HS3ST1heparan sulfate (glucosamine) 3-O-sulfotransferase 1Pancreas+4.930.000
115SLC30A2solute carrier family 30 (zinc transporter), member 2Pancreas-4.930.000
116ANO1anoctamin 1, calcium activated chloride channelPancreas+4.920.000
117CSTAcystatin A (stefin A)Pancreas+4.900.000
118AOX1aldehyde oxidase 1Pancreas-4.900.000
119ECT2epithelial cell transforming 2Pancreas+4.880.000
120KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)Pancreas+4.880.000
121BACE1beta-site APP-cleaving enzyme 1Pancreas-4.870.000
122CYP1B1cytochrome P450, family 1, subfamily B, polypeptide 1Pancreas+4.870.000
123TMEM97transmembrane protein 97Pancreas-4.870.000
124CXCL14chemokine (C-X-C motif) ligand 14Pancreas+4.860.000
125IL22RA1interleukin 22 receptor, alpha 1Pancreas-4.860.000
126HMCN1hemicentin 1Pancreas+4.850.000
127CXCR4chemokine (C-X-C motif) receptor 4Pancreas+4.850.000
128MMP1matrix metallopeptidase 1 (interstitial collagenase)Pancreas+4.850.001
129GAMTguanidinoacetate N-methyltransferasePancreas-4.840.000
130BCL2A1BCL2-related protein A1Pancreas+4.830.000
131TRHDEthyrotropin-releasing hormone degrading enzymePancreas-4.830.000
132GCNT3glucosaminyl (N-acetyl) transferase 3, mucin typePancreas+4.820.000
133CCKBRcholecystokinin B receptorPancreas-4.820.000
134AREGamphiregulinPancreas+4.820.000
135ZNF207zinc finger protein 207Pancreas+4.810.000
136SLC6A6solute carrier family 6 (neurotransmitter transporter), member 6Pancreas+4.810.000
137SPARCsecreted protein, acidic, cysteine-rich (osteonectin)Pancreas+4.800.000
138GABRPgamma-aminobutyric acid (GABA) A receptor, piPancreas+4.790.001
139HOMER2homer homolog 2 (Drosophila)Pancreas-4.790.000
140IFI44interferon-induced protein 44Pancreas+4.790.000
141PHLDA1pleckstrin homology-like domain, family A, member 1Pancreas+4.790.000
142SLC43A1solute carrier family 43 (amino acid system L transporter), member 1Pancreas-4.780.000
143HLA-DPA1major histocompatibility complex, class II, DP alpha 1Pancreas+4.780.000
144SEL1Lsel-1 suppressor of lin-12-like (C. elegans)Pancreas-4.780.000
145PELI1pellino E3 ubiquitin protein ligase 1Pancreas+4.770.000
146ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)Pancreas+4.770.000
147STAT1signal transducer and activator of transcription 1, 91kDaPancreas+4.770.000
148TPSB2tryptase beta 2 (gene/pseudogene)Pancreas+4.760.000
149LAMA4laminin, alpha 4Pancreas+4.760.000
150LINC00339long intergenic non-protein coding RNA 339Pancreas-4.760.000
151HLA-DQB1major histocompatibility complex, class II, DQ beta 1Pancreas+4.760.000
152RGS1regulator of G-protein signaling 1Pancreas+4.730.000
153ITGBL1integrin, beta-like 1 (with EGF-like repeat domains)Pancreas+4.720.000
154ALDOBaldolase B, fructose-bisphosphatePancreas-4.720.000
155CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)Pancreas+4.720.000
156KRT19keratin 19Pancreas+4.710.000
157NREPneuronal regeneration related proteinPancreas+4.700.000
158SYTL2synaptotagmin-like 2Pancreas+4.700.000
159NQO1NAD(P)H dehydrogenase, quinone 1Pancreas+4.690.000
160GPX2glutathione peroxidase 2 (gastrointestinal)Pancreas+4.690.001
161GPNMBglycoprotein (transmembrane) nmbPancreas+4.690.000
162ITGB6integrin, beta 6Pancreas+4.670.000
163HPGDhydroxyprostaglandin dehydrogenase 15-(NAD)Pancreas+4.670.000
164TNFSF13Btumor necrosis factor (ligand) superfamily, member 13bPancreas+4.660.000
165MPEG1macrophage expressed 1Pancreas+4.660.000
166LAMC2laminin, gamma 2Pancreas+4.660.000
167CCL20chemokine (C-C motif) ligand 20Pancreas+4.660.000
168ZEB2zinc finger E-box binding homeobox 2Pancreas+4.660.000
169LAMA3laminin, alpha 3Pancreas+4.630.000
170JMJD1Cjumonji domain containing 1CPancreas+4.630.000
171DEFB1defensin, beta 1Pancreas-4.630.000
172EPSTI1epithelial stromal interaction 1 (breast)Pancreas+4.620.000
173CD109CD109 moleculePancreas+4.610.000
174LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)Pancreas+4.590.000
175ARSEarylsulfatase E (chondrodysplasia punctata 1)Pancreas-4.580.000
176CTSKcathepsin KPancreas+4.570.000
177CD52CD52 moleculePancreas+4.570.000
178REG1Aregenerating islet-derived 1 alphaPancreas-4.560.016
179TGFBR1transforming growth factor, beta receptor 1Pancreas+4.550.000
180CASP1caspase 1, apoptosis-related cysteine peptidasePancreas+4.550.000
181CCDC80coiled-coil domain containing 80Pancreas+4.550.000
182CST1cystatin SNPancreas+4.530.000
183FBN1fibrillin 1Pancreas+4.520.000
184DPEP1dipeptidase 1 (renal)Pancreas-4.500.000
185GPR183G protein-coupled receptor 183Pancreas+4.500.000
186IGLimmunoglobulin lambda locusPancreas+4.490.000
187PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)Pancreas+4.490.001
188GLT8D2glycosyltransferase 8 domain containing 2Pancreas+4.460.000
189EGR2early growth response 2Pancreas+4.460.000
190KLK10kallikrein-related peptidase 10Pancreas+4.440.002
191THBS2thrombospondin 2Pancreas+4.440.000
192CAPN8calpain 8Pancreas+4.430.000
193NR5A2nuclear receptor subfamily 5, group A, member 2Pancreas-4.430.000
194PDLIM3PDZ and LIM domain 3Pancreas+4.430.000
195ANTXR1anthrax toxin receptor 1Pancreas+4.420.000
196ANPEPalanyl (membrane) aminopeptidasePancreas-4.420.002
197ADCY7adenylate cyclase 7Pancreas+4.410.000
198OAS12'-5'-oligoadenylate synthetase 1, 40/46kDaPancreas+4.400.000
199PDK4pyruvate dehydrogenase kinase, isozyme 4Pancreas-4.390.000
200COCHcochlinPancreas-4.380.000
201GUCA1Cguanylate cyclase activator 1CPancreas-4.380.000
202P2RX1purinergic receptor P2X, ligand-gated ion channel, 1Pancreas-4.370.000
203FAM26Ffamily with sequence similarity 26, member FPancreas+4.370.000
204TAGAPT-cell activation RhoGTPase activating proteinPancreas+4.360.000
205IGKV4-1immunoglobulin kappa variable 4-1Pancreas+4.360.000
206PRDM1PR domain containing 1, with ZNF domainPancreas+4.360.000
207EVI2Becotropic viral integration site 2BPancreas+4.350.000
208LOC284454uncharacterized LOC284454Pancreas+4.340.000
209C5complement component 5Pancreas-4.340.000
210TRIM14tripartite motif containing 14Pancreas+4.340.000
211CEMIPcell migration inducing protein, hyaluronan bindingPancreas+4.330.000
212OSBPL3oxysterol binding protein-like 3Pancreas+4.330.000
213KIAA1324KIAA1324Pancreas-4.320.000
214HNRNPU-AS1HNRNPU antisense RNA 1Pancreas+4.320.000
215GPR34G protein-coupled receptor 34Pancreas+4.310.000
216ERO1LBERO1-like beta (S. cerevisiae)Pancreas-4.310.000
217IL8interleukin 8Pancreas+4.300.000
218C19orf33chromosome 19 open reading frame 33Pancreas+4.300.000
219C15orf48chromosome 15 open reading frame 48Pancreas+4.300.000
220CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)Pancreas+4.290.000
221IL18interleukin 18 (interferon-gamma-inducing factor)Pancreas+4.290.000
222IGFBP3insulin-like growth factor binding protein 3Pancreas+4.290.001
223NOX4NADPH oxidase 4Pancreas+4.290.000
224KCNJ16potassium inwardly-rectifying channel, subfamily J, member 16Pancreas-4.290.000
225SERPINB5serpin peptidase inhibitor, clade B (ovalbumin), member 5Pancreas+4.280.000
226IL1RNinterleukin 1 receptor antagonistPancreas+4.280.000
227GPR137BG protein-coupled receptor 137BPancreas+4.280.000
228CA12carbonic anhydrase XIIPancreas-4.280.000
229FPR3formyl peptide receptor 3Pancreas+4.270.000
230HSPA6heat shock 70kDa protein 6 (HSP70B')Pancreas+4.270.000
231RUNX1runt-related transcription factor 1Pancreas+4.270.000
232DPY19L1dpy-19-like 1 (C. elegans)Pancreas+4.270.000
233HPNhepsinPancreas-4.270.000
234CD69CD69 moleculePancreas+4.260.000
235GBP3guanylate binding protein 3Pancreas+4.250.000
236CXCL3chemokine (C-X-C motif) ligand 3Pancreas+4.240.000
237COA1cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)Pancreas+4.240.000
238NCF2neutrophil cytosolic factor 2Pancreas+4.240.000
239DLEU2deleted in lymphocytic leukemia 2 (non-protein coding)Pancreas+4.240.000
240LAMB3laminin, beta 3Pancreas+4.240.000
241ADAM28ADAM metallopeptidase domain 28Pancreas+4.230.000
242PSAT1phosphoserine aminotransferase 1Pancreas-4.230.000
243CHRM3cholinergic receptor, muscarinic 3Pancreas-4.220.000
244SLC38A5solute carrier family 38, member 5Pancreas-4.210.000
245OLR1oxidized low density lipoprotein (lectin-like) receptor 1Pancreas+4.210.000
246CMAHPcytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogenePancreas+4.210.000
247GPRC5AG protein-coupled receptor, class C, group 5, member APancreas+4.210.000
248AHNAK2AHNAK nucleoprotein 2Pancreas+4.200.000
249CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)Pancreas+4.200.000
250OSBPL10oxysterol binding protein-like 10Pancreas+4.200.000
251SH3KBP1SH3-domain kinase binding protein 1Pancreas+4.190.000
252IL2RGinterleukin 2 receptor, gammaPancreas+4.190.000
253ACSL5acyl-CoA synthetase long-chain family member 5Pancreas+4.180.000
254KRT17keratin 17Pancreas+4.180.000
255IGHMimmunoglobulin heavy constant muPancreas+4.170.000
256SDR16C5short chain dehydrogenase/reductase family 16C, member 5Pancreas+4.170.001
257CD86CD86 moleculePancreas+4.170.000
258AKR1B10aldo-keto reductase family 1, member B10 (aldose reductase)Pancreas+4.170.003
259BIRC3baculoviral IAP repeat containing 3Pancreas+4.170.000
260SLC2A3solute carrier family 2 (facilitated glucose transporter), member 3Pancreas+4.170.000
261TRIOtrio Rho guanine nucleotide exchange factorPancreas+4.170.000
262TPSAB1tryptase alpha/beta 1Pancreas+4.160.000
263FAM150Bfamily with sequence similarity 150, member BPancreas-4.160.000
264GIMAP2GTPase, IMAP family member 2Pancreas+4.150.000
265PLAURplasminogen activator, urokinase receptorPancreas+4.140.000
266LOXlysyl oxidasePancreas+4.140.000
267MS4A6Amembrane-spanning 4-domains, subfamily A, member 6APancreas+4.140.000
268CTSScathepsin SPancreas+4.130.000
269PLXNC1plexin C1Pancreas+4.120.000
270PHLDA2pleckstrin homology-like domain, family A, member 2Pancreas+4.110.000
271RBP1retinol binding protein 1, cellularPancreas-4.110.000
272GZMAgranzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)Pancreas+4.110.000
273POU2AF1POU class 2 associating factor 1Pancreas+4.100.000
274OGNosteoglycinPancreas+4.100.000
275DKK3dickkopf WNT signaling pathway inhibitor 3Pancreas+4.100.000
276FCGR2BFc fragment of IgG, low affinity IIb, receptor (CD32)Pancreas+4.100.000
277RASGRP1RAS guanyl releasing protein 1 (calcium and DAG-regulated)Pancreas+4.090.000
278SPON1spondin 1, extracellular matrix proteinPancreas+4.080.000
279ACADLacyl-CoA dehydrogenase, long chainPancreas-4.080.000
280LOXL1lysyl oxidase-like 1Pancreas+4.080.000
281CD74CD74 molecule, major histocompatibility complex, class II invariant chainPancreas+4.070.000
282CLEC7AC-type lectin domain family 7, member APancreas+4.060.000
283REG4regenerating islet-derived family, member 4Pancreas+4.060.038
284CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)Pancreas+4.060.000
285LACC1laccase (multicopper oxidoreductase) domain containing 1Pancreas+4.060.000
286UHRF1BP1LUHRF1 binding protein 1-likePancreas+4.060.000
287ALG13ALG13, UDP-N-acetylglucosaminyltransferase subunitPancreas+4.050.000
288ZBTB16zinc finger and BTB domain containing 16Pancreas-4.020.000
289SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1Pancreas-4.000.000
290H19H19, imprinted maternally expressed transcript (non-protein coding)Pancreas-3.980.010
291ITIH4inter-alpha-trypsin inhibitor heavy chain family, member 4Pancreas-3.960.000
292LGALS2lectin, galactoside-binding, soluble, 2Pancreas-3.940.001
293PRSS2protease, serine, 2 (trypsin 2)Pancreas-3.930.026
294ACSM3acyl-CoA synthetase medium-chain family member 3Pancreas-3.920.000
295KIF1Akinesin family member 1APancreas-3.920.000
296INSRinsulin receptorPancreas-3.890.000
297PDCD4programmed cell death 4 (neoplastic transformation inhibitor)Pancreas-3.880.000
298SERPINA4serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4Pancreas-3.870.000
299C6complement component 6Pancreas-3.840.000
300KCNK3potassium channel, subfamily K, member 3Pancreas-3.830.000
301GPT2glutamic pyruvate transaminase (alanine aminotransferase) 2Pancreas-3.810.000
302COMTD1catechol-O-methyltransferase domain containing 1Pancreas-3.810.000
303F8coagulation factor VIII, procoagulant componentPancreas-3.790.000
304PGBD5piggyBac transposable element derived 5Pancreas-3.790.000
305SFRP5secreted frizzled-related protein 5Pancreas-3.790.000
306LEFTY1left-right determination factor 1Pancreas-3.770.005
307KIRREL2kin of IRRE like 2 (Drosophila)Pancreas-3.760.000
308TM7SF2transmembrane 7 superfamily member 2Pancreas-3.760.000
309DAPL1death associated protein-like 1Pancreas-3.750.000
310IMPA2inositol(myo)-1(or 4)-monophosphatase 2Pancreas-3.750.000
311FXYD2FXYD domain containing ion transport regulator 2Pancreas-3.740.000
312PLXNA2plexin A2Pancreas-3.730.000
313NPTX2neuronal pentraxin IIPancreas-3.710.000
314SSFA2sperm specific antigen 2Pancreas-3.700.000
315SLC25A15solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15Pancreas-3.660.000
316NTRK2neurotrophic tyrosine kinase, receptor, type 2Pancreas-3.650.000
317DLK1delta-like 1 homolog (Drosophila)Pancreas-3.650.001
318FABP4fatty acid binding protein 4, adipocytePancreas-3.630.008
319LOC553137uncharacterized LOC553137Pancreas-3.610.000
320ECHDC3enoyl CoA hydratase domain containing 3Pancreas-3.610.000
321GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)Pancreas-3.600.000
322PHGDHphosphoglycerate dehydrogenasePancreas-3.580.000
323SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2Pancreas-3.560.000
324CRYBA2crystallin, beta A2Pancreas-3.560.000
325KCNJ8potassium inwardly-rectifying channel, subfamily J, member 8Pancreas-3.540.000
326HSD17B8hydroxysteroid (17-beta) dehydrogenase 8Pancreas-3.530.000
327SLC1A4solute carrier family 1 (glutamate/neutral amino acid transporter), member 4Pancreas-3.520.000
328SLC39A8solute carrier family 39 (zinc transporter), member 8Pancreas-3.500.000
329FOXA3forkhead box A3Pancreas-3.460.000
330FAM3Bfamily with sequence similarity 3, member BPancreas-3.430.003
331SERPINA5serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5Pancreas-3.420.001
332SERPINA3serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3Pancreas-3.400.007
333S100A12S100 calcium binding protein A12Pancreas-3.370.000
334C19orf48chromosome 19 open reading frame 48Pancreas-3.350.000
335SPAG4sperm associated antigen 4Pancreas-3.340.000
336PARM1prostate androgen-regulated mucin-like protein 1Pancreas-3.340.000
337RHOBTB3Rho-related BTB domain containing 3Pancreas-3.330.000
338CLDN10claudin 10Pancreas-3.300.025
339RPH3ALrabphilin 3A-like (without C2 domains)Pancreas-3.300.000
340MTUS2microtubule associated tumor suppressor candidate 2Pancreas-3.290.000
341CTNND2catenin (cadherin-associated protein), delta 2Pancreas-3.290.000
342BSPRYB-box and SPRY domain containingPancreas-3.290.000
343LINC00261long intergenic non-protein coding RNA 261Pancreas-3.290.000
344SSTsomatostatinPancreas-3.260.033
345RAB3DRAB3D, member RAS oncogene familyPancreas-3.250.000
346BTG2BTG family, member 2Pancreas-3.240.000
347NLE1notchless homolog 1 (Drosophila)Pancreas-3.230.000
348CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)Pancreas-3.210.016
349DCDC2doublecortin domain containing 2Pancreas-3.200.001
350ANXA9annexin A9Pancreas-3.180.000
351TPST2tyrosylprotein sulfotransferase 2Pancreas-3.170.000
352USTuronyl-2-sulfotransferasePancreas-3.170.000
353MSRB1methionine sulfoxide reductase B1Pancreas-3.170.000
354MAOAmonoamine oxidase APancreas-3.150.000
355PAK3p21 protein (Cdc42/Rac)-activated kinase 3Pancreas-3.130.000
356PDE8Bphosphodiesterase 8BPancreas-3.120.000
357TMEM125transmembrane protein 125Pancreas-3.120.000
358CLDN3claudin 3Pancreas-3.120.011
359C21orf2chromosome 21 open reading frame 2Pancreas-3.120.000
360P4HBprolyl 4-hydroxylase, beta polypeptidePancreas-3.120.000
361SLC38A4solute carrier family 38, member 4Pancreas-3.110.000
362SYTL1synaptotagmin-like 1Pancreas-3.110.000
363VEPH1ventricular zone expressed PH domain-containing 1Pancreas-3.100.000
364STXBP6syntaxin binding protein 6 (amisyn)Pancreas-3.090.000
365TPM1tropomyosin 1 (alpha)Pancreas-3.090.000
366PIFOprimary cilia formationPancreas-3.090.000
367KLHDC10kelch domain containing 10Pancreas-3.080.000
368SLC3A1solute carrier family 3 (amino acid transporter heavy chain), member 1Pancreas-3.080.034
369DHRS12dehydrogenase/reductase (SDR family) member 12Pancreas-3.080.000
370SLC37A4solute carrier family 37 (glucose-6-phosphate transporter), member 4Pancreas-3.070.000
371ARRB1arrestin, beta 1Pancreas-3.070.000
372APLP1amyloid beta (A4) precursor-like protein 1Pancreas-3.020.000
373MUC15mucin 15, cell surface associatedPancreas-3.020.000
374STC2stanniocalcin 2Pancreas-3.020.000
375BEX5brain expressed, X-linked 5Pancreas-3.010.001
376FUT1fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)Pancreas-3.000.000
377NR0B2nuclear receptor subfamily 0, group B, member 2Pancreas-2.990.000
378HBBhemoglobin, betaPancreas-2.980.004
379GCATglycine C-acetyltransferasePancreas-2.980.000
380KCTD14potassium channel tetramerization domain containing 14Pancreas-2.980.000
381GATSGATS, stromal antigen 3 opposite strandPancreas-2.950.000
382ABHD12abhydrolase domain containing 12Pancreas-2.940.000
383CHGAchromogranin A (parathyroid secretory protein 1)Pancreas-2.940.002
384MACROD1MACRO domain containing 1Pancreas-2.940.000
385TMPRSS2transmembrane protease, serine 2Pancreas-2.940.000
386C4orf19chromosome 4 open reading frame 19Pancreas-2.930.000
387QSER1glutamine and serine rich 1Pancreas-2.930.000
388RGNregucalcinPancreas-2.930.000
389SCGNsecretagogin, EF-hand calcium binding proteinPancreas-2.920.002
390RAP1GAPRAP1 GTPase activating proteinPancreas-2.920.000
391PPAPDC1Bphosphatidic acid phosphatase type 2 domain containing 1BPancreas-2.880.000
392PTGER3prostaglandin E receptor 3 (subtype EP3)Pancreas-2.870.000
393SLC16A10solute carrier family 16 (aromatic amino acid transporter), member 10Pancreas-2.870.000
394SLC39A14solute carrier family 39 (zinc transporter), member 14Pancreas-2.860.000
395FKBP11FK506 binding protein 11, 19 kDaPancreas-2.850.000
396DNAJC12DnaJ (Hsp40) homolog, subfamily C, member 12Pancreas-2.830.001
397GATA4GATA binding protein 4Pancreas-2.820.000
398SYNE2spectrin repeat containing, nuclear envelope 2Pancreas-2.820.000
399CCDC110coiled-coil domain containing 110Pancreas-2.810.000
400TMEM163transmembrane protein 163Pancreas-2.810.003

Expression patterns in normal tissues for genes affiliated with Pancreatic Ductal Adenocarcinoma

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Pathways for genes affiliated with Pancreatic Ductal Adenocarcinoma

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Pathways related to Pancreatic Ductal Adenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4MIR21, MIR181B1
28.6MIR21, MIR10B, MIR224, MIR181B1

Compounds for genes affiliated with Pancreatic Ductal Adenocarcinoma

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GO Terms for genes affiliated with Pancreatic Ductal Adenocarcinoma

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Products for genes affiliated with Pancreatic Ductal Adenocarcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Pancreatic Ductal Adenocarcinoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet