MCID: PNC053
MIFTS: 35

Pancreatic Islet Cell Tumors malady

Categories: Rare diseases, Endocrine diseases, Cancer diseases

Aliases & Classifications for Pancreatic Islet Cell Tumors

Aliases & Descriptions for Pancreatic Islet Cell Tumors:

Name: Pancreatic Islet Cell Tumors 50 69
Pancreatic Endocrine Carcinoma 69
Islet of Langerhans Tumor 50
Islet Cell Carcinoma 50
Islet Cell Tumors 50
Islet Cell Tumor 69

Classifications:



Summaries for Pancreatic Islet Cell Tumors

MalaCards based summary : Pancreatic Islet Cell Tumors, also known as pancreatic endocrine carcinoma, is related to pheochromocytoma and pancreatic endocrine carcinoma. An important gene associated with Pancreatic Islet Cell Tumors is SST (Somatostatin), and among its related pathways/superpathways is Signaling by GPCR. The drugs Etanercept and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include pancreatic islet, liver and pituitary.

Related Diseases for Pancreatic Islet Cell Tumors

Diseases related to Pancreatic Islet Cell Tumors via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)
id Related Disease Score Top Affiliating Genes
1 pheochromocytoma 29.8 CALCA MEN1 SST
2 pancreatic endocrine carcinoma 11.0
3 pancreatitis 10.7
4 islet cell tumor 10.7
5 shaken baby syndrome 10.2 INS SST
6 protein s deficiency 10.2 INS SST
7 photoparoxysmal response 3 10.2 INS SST
8 adult botryoid rhabdomyosarcoma 10.2 NTS SST
9 merkel cell carcinoma 10.2 INS SST
10 wells-jankovic syndrome 10.2 CALCA SST
11 secondary syphilis 10.2 GAST SST
12 brain edema 10.2 GAST SST
13 nutritional optic neuropathy 10.2 GAST SST
14 cherubism 10.2 GAST SST
15 myocardial stunning 10.2 GAST SST
16 lung occult small cell carcinoma 10.2 CALCA SST
17 diabetic cataract 10.2 INS SST
18 vein disease 10.2 GAST INS
19 color blindness 10.2 GAST SST
20 rickets 10.2 NTS SST
21 cockayne syndrome type i 10.2 CALCA INS
22 neurogenic arthropathy 10.1 INS SST
23 hemopericardium 10.1 CALCA INS
24 adrenal cortical adenocarcinoma 10.1 INS SST
25 retinal telangiectasia 10.1 GAST SST
26 alpha-heavy chain disease 10.1 CALCA GAST
27 adult brain stem glioma 10.1 GAST NTS
28 axial osteomalacia 10.1 CALCA SST
29 childhood intracortical osteosarcoma 10.1 GAST SST
30 bizarre leiomyoma 10.1 CALCA GAST
31 choline deficiency disease 10.1 INS NTS SST
32 uterine ligament cancer 10.1 MEN1 SST
33 peripheral degeneration of cornea 10.1 INS NTS SST
34 early-onset parkinson disease 10.1 MEN1 SST
35 multiple endocrine neoplasia 10.1
36 chondroma 10.1 INS SST
37 mitochondrial complex ii deficiency 10.0 MEN1 SST
38 tabes dorsalis 10.0 MEN1 SST
39 pulmonary neuroendocrine tumor 10.0 MEN1 SST
40 brain ependymoma 10.0 CALCA INS SST
41 spinal stenosis 10.0 CALCA INS SST
42 retinal vascular occlusion 10.0 GAST INS SST
43 neuroretinitis 10.0 MEN1 SST
44 tricuspid valve stenosis 10.0 GAST NTS SST
45 sweat gland cancer 10.0 GAST NTS SST
46 rheumatic encephalitis 10.0 MEN1 SST
47 adult ependymoblastoma 10.0 CALCA MEN1
48 hyperornithinemia-hyperammonemia-homocitrullinemia syndrome 10.0 GAST NTS
49 breast malignant eccrine spiradenoma 10.0 GAST MEN1
50 hirschsprung disease 1 10.0 CALCA MEN1

Graphical network of the top 20 diseases related to Pancreatic Islet Cell Tumors:



Diseases related to Pancreatic Islet Cell Tumors

Symptoms & Phenotypes for Pancreatic Islet Cell Tumors

Drugs & Therapeutics for Pancreatic Islet Cell Tumors

Drugs for Pancreatic Islet Cell Tumors (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 223)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etanercept Approved, Investigational Phase 4,Phase 1,Phase 2 185243-69-0
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
3
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
4
Sunitinib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 341031-54-7, 557795-19-4 5329102
5
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
6
Pancrelipase Approved Phase 4,Phase 3,Phase 2,Phase 1 53608-75-6
7
Somatostatin Approved Phase 4,Phase 3,Phase 2,Phase 1 38916-34-6, 51110-01-1 53481605
8
Zinc Approved Phase 4 7440-66-6 32051 23994
9
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
10 pancreatin Phase 4,Phase 3,Phase 2,Phase 1
11 pancreatic polypeptide Phase 4,Phase 2,Phase 3,Phase 1
12 Analgesics Phase 4,Phase 3,Phase 1,Phase 2
13 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
14 Analgesics, Non-Narcotic Phase 4,Phase 1,Phase 2
15 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
17 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2
18 Angiogenesis Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
20 Angiogenesis Modulating Agents Phase 4,Phase 2,Phase 3,Phase 1
21 Hypoglycemic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
22 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
23 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1
25 Anti-Inflammatory Agents Phase 4,Phase 1,Phase 2
26 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 1,Phase 2
28 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1
29 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1
30 Antirheumatic Agents Phase 4,Phase 1,Phase 2
31 insulin Phase 4,Phase 2
32
Dexlansoprazole Phase 4 138530-94-6, 103577-45-3 9578005
33
Proton pump inhibitors Phase 4,Phase 3,Phase 2
34 Antacids Phase 4,Phase 3,Phase 2
35 Insulin, Globin Zinc Phase 4,Phase 2
36 Anti-Ulcer Agents Phase 4,Phase 3,Phase 2
37
protease inhibitors Phase 4,Phase 2
38 Serine Proteinase Inhibitors Phase 4
39 Alpha 1-Antitrypsin Phase 4
40 HIV Protease Inhibitors Phase 4,Phase 2
41 Trypsin Inhibitors Phase 4
42 Fluorodeoxyglucose F18 Phase 4,Phase 2
43 Protein C Phase 4
44 Protein C Inhibitor Phase 4
45 serine Nutraceutical Phase 4
46
Oxaliplatin Approved, Investigational Phase 2, Phase 3,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
47
Exenatide Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 141758-74-9 15991534
48
Fluorouracil Approved Phase 2, Phase 3, Phase 1 51-21-8 3385
49
Bevacizumab Approved, Investigational Phase 2, Phase 3 216974-75-3
50
Levoleucovorin Approved Phase 2, Phase 3,Phase 1 68538-85-2

Interventional clinical trials:

(show top 50) (show all 189)
id Name Status NCT ID Phase
1 Disease-Specific Questionnaire in Assessing Quality of Life in Patients With Gastrointestinal-Related Neuroendocrine Tumors Unknown status NCT00454376 Phase 4
2 Treatment of Zollinger-Ellison Syndrome With Prevacid Completed NCT00204373 Phase 4
3 Nonfunctional Pancreatic NET and PET Imaging Recruiting NCT02621541 Phase 4
4 Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China Recruiting NCT02842749 Phase 4
5 Anti-inflammatory Therapy to Improve Outcomes After TPIAT Recruiting NCT02713997 Phase 4
6 Clinical Effectiveness of Serum Chromogranin A Levels on Diagnostic of Pancreatic Neuroendocrine Tumors Active, not recruiting NCT02759718 Phase 4
7 A Study Of The Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors Active, not recruiting NCT01525550 Phase 4
8 Pasireotide Treatment for Neuroendocrine Tumor Withdrawn NCT02779257 Phase 4
9 Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors Unknown status NCT00227617 Phase 2, Phase 3
10 Study of Lanreotide Autogel 120 mg in Patients With Non-functioning Entero- Pancreatic Endocrine Tumour Completed NCT00842348 Phase 3
11 Study of Lanreotide Autogel in Non-functioning Entero-pancreatic Endocrine Tumours Completed NCT00353496 Phase 3
12 Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors Completed NCT00510068 Phase 3
13 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3
14 Safety and Efficacy Study of In-111 Pentetreotide to Treat Neuroendocrine Tumors Completed NCT00442533 Phase 2, Phase 3
15 Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome Completed NCT00079833 Phase 3
16 A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases Completed NCT02153398 Phase 3
17 A Study Evaluating Lanreotide as Maintenance Therapy in Patients With Non-Resectable Duodeno-Pancreatic Neuroendocrine Tumors (REMINET) Recruiting NCT02288377 Phase 2, Phase 3
18 Phase III Study of Sulfatinib in Treating Advanced Pancreatic Neuroendocrine Tumors Recruiting NCT02589821 Phase 3
19 Efficacy and Safety of Radiofrequency Ablation in Pancreatic Neuroendocrine and Cystic Tumor Recruiting NCT02330497 Phase 3
20 Efficacy and Safety of Everolimus and (STZ-5FU) Given One Upfront the Other Upon Progression in Advanced pNET Recruiting NCT02246127 Phase 3
21 New Imaging Procedure for the Localisation of Insulinoma and Transplanted Islet Cells Recruiting NCT02127541 Phase 2, Phase 3
22 18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety Recruiting NCT03042416 Phase 3
23 Clinical Evaluation Of Needle-based Confocal Laser Endomicroscopy in The Lymph Nodes Along With Masses and Cystic Tumors of the Pancreas Active, not recruiting NCT01563133 Phase 3
24 Non-functioning Pancreatic Neuroendocrine Tumors in MEN1: Somatostatin Analogs Versus NO Treatment Not yet recruiting NCT02705651 Phase 3
25 A Study Of Sunitinib Compared To Placebo For Patients With Advanced Pancreatic Islet Cell Tumors Terminated NCT00428597 Phase 3
26 68-Ga-labeled Octreotide Analogues PET in Duodenal-pancreatic Neuroendocrine Tumours Unknown status NCT01673906 Phase 2
27 Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs Unknown status NCT02294006 Phase 2
28 Single Arm Trial With Combination of Everolimus and Letrozole in Treatment of Platinum Resistant Relapse or Refractory or Persistent Ovarian Cancer/Endometrial Cancer Unknown status NCT02188550 Phase 2
29 Islet Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression Unknown status NCT00566813 Phase 1, Phase 2
30 RAD001 and Erlotinib in Patients With Neuroendocrine Tumors Unknown status NCT00843531 Phase 2
31 A Study of IMC-A12 in Islet Cell Cancer Completed NCT00781911 Phase 2
32 Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors Completed NCT00602082 Phase 2
33 Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery Completed NCT00416767 Phase 2
34 RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma Completed NCT00113360 Phase 2
35 Phase II Study of Sunitinib Malate Following Hepatic Artery Embolization Completed NCT00434109 Phase 2
36 Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas Completed NCT00001165 Phase 2
37 PS-341 in Treating Patients With Metastatic Neuroendocrine Tumors Completed NCT00017199 Phase 2
38 Pazopanib as Single Agent in Advanced NETs Completed NCT01280201 Phase 2
39 AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors Completed NCT00427349 Phase 2
40 Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy Completed NCT00363051 Phase 2
41 Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors Completed NCT00027638 Phase 2
42 Study of MK-2206 in Patients With Metastatic Neuroendocrine Tumors (NET) Completed NCT01169649 Phase 2
43 The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid Completed NCT00001191 Phase 2
44 BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy. Completed NCT01658436 Phase 2
45 Chemotherapy Plus Endostatin in Advanced Pancreatic Neuroendocrine Tumor Completed NCT01845675 Phase 2
46 Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases Completed NCT00019786 Phase 2
47 Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors Completed NCT01121562 Phase 2
48 Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma Completed NCT00093782 Phase 2
49 Sorafenib Tosylate in Treating Patients With Progressive Metastatic Neuroendocrine Tumors Completed NCT00131911 Phase 2
50 Gefitinib in Treating Patients With Progressive Metastatic Neuroendocrine Tumors Completed NCT00075439 Phase 2

Search NIH Clinical Center for Pancreatic Islet Cell Tumors

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Pancreatic Islet Cell Tumors

Anatomical Context for Pancreatic Islet Cell Tumors

MalaCards organs/tissues related to Pancreatic Islet Cell Tumors:

39
Pancreatic Islet, Liver, Pituitary, Testes

Publications for Pancreatic Islet Cell Tumors

Articles related to Pancreatic Islet Cell Tumors:

(show top 50) (show all 96)
id Title Authors Year
1
Characterization of a pancreatic islet cell tumor in a polar bear (Ursus maritimus). ( 25273481 )
2014
2
Surgical treatment of pancreatic islet cell tumor: report of 44 cases. ( 24719954 )
2013
3
Metastatic Insulinoma Following Resection of Nonsecreting Pancreatic Islet Cell Tumor: A Case Report and Review of the Literature. ( 26425568 )
2013
4
Sorafenib inhibits tumor growth and improves survival in a transgenic mouse model of pancreatic islet cell tumors. ( 23346016 )
2012
5
Pancreatic and peri-pancreatic lesions mimic pancreatic islet cell tumor in multidetector computed tomography. ( 21740785 )
2011
6
Systematic comparison of sporadic and syndromic pancreatic islet cell tumors. ( 20660572 )
2010
7
Diffusion weighted MR imaging of pancreatic islet cell tumors. ( 19264435 )
2010
8
Pancreatic islet cell tumor secreting insulin-like growth factor type-II in a dog. ( 19780935 )
2009
9
Spontaneous pancreatic islet cell tumor in a black and white colobus monkey (Colobus guereza kikuyuensis). ( 18269522 )
2008
10
Hypoglycemia associated with the production of insulin-like growth factor II in a pancreatic islet cell tumor: a case report. ( 18490836 )
2008
11
Extensive acrochordons and pancreatic islet-cell tumors in tuberous sclerosis associated with TSC2 mutations. ( 16835931 )
2006
12
Multi-detector row CT of pancreatic islet cell tumors. ( 16549609 )
2006
13
Surgical treatment of non-functioning pancreatic islet cell tumors. ( 15719379 )
2005
14
Endoscopic ultrasonography of nonfunctioning pancreatic islet cell tumors with histologic correlation. ( 15532784 )
2004
15
Non-islet origin of pancreatic islet cell tumors. ( 15070966 )
2004
16
Pancreatic islet cell tumor in a domestic ferret. ( 14615962 )
2003
17
High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant conversion in VHL tumorigenesis. ( 11929809 )
2002
18
Streptozocin for treatment of pancreatic islet cell tumors in dogs: 17 cases (1989-1999). ( 12322919 )
2002
19
Sonographic diagnosis of pancreatic islet cell tumor: value of intermittent harmonic imaging. ( 11579405 )
2001
20
Induction of pancreatic islet cell tumors in rats by repeated intravenous administration of 4-hydroxyaminoquinoline 1-oxide. ( 11442018 )
2001
21
Ultrasound-guided laparoscopic resection of pancreatic islet cell tumors. ( 10872980 )
2000
22
Large and asymptomatic pancreatic islet cell tumor in a patient with multiple endocrine neoplasia type 1. ( 11216636 )
2000
23
Evaluation of pancreatic islet cell tumors by fluorine-18 fluorodeoxyglucose positron emission tomography: comparison with other modalities. ( 10656646 )
2000
24
Pancreatitis associated with pancreatic islet cell tumors. ( 10414710 )
1999
25
Functional pancreatic islet cell tumors with liver metastasis: the role of cytoreductive surgery and transcatheter arterial chemoembolization: a report of five cases. ( 9884450 )
1998
26
Surgical decision-making affected by clinical and genetic screening of a novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors. ( 9488521 )
1998
27
Pancreatic islet cell tumor metastasis in multiple endocrine neoplasia type 1: correlation with primary tumor size. ( 9854581 )
1998
28
Immunohistochemistry of pancreatic islet cell tumors in the ferret (Mustela putorius furo). ( 9381649 )
1997
29
Pancreatic polypeptide is a useful plasma marker for radiographically evident pancreatic islet cell tumors in patients with multiple endocrine neoplasia type 1. ( 9426414 )
1997
30
Pancreatic islet cell tumor producing vasoactive intestinal polypeptide and calcitonin. ( 9494586 )
1997
31
Absence of RET proto-oncogene mutations in a father and son with pheochromocytoma and pancreatic islet cell tumor. ( 9179691 )
1997
32
A growth hormone-releasing hormone-producing pancreatic islet cell tumor metastasized to the pituitary is associated with pituitary somatotroph hyperplasia and acromegaly. ( 9253362 )
1997
33
Chromogranin A plasma concentration and expression in pancreatic islet cell tumors of dogs and cats. ( 9185968 )
1997
34
[Immunohistochemical studies of nonsecreting pancreatic islet cell tumors secreting many hormones]. ( 9388878 )
1996
35
Diagnosis and treatment of insulin-secreting pancreatic islet cell tumors in ferrets: 57 cases (1986-1994). ( 8921033 )
1996
36
Comparison of chromogranin A and pancreastatin levels in plasma of patients with pancreatic islet cell tumor. ( 7630318 )
1995
37
The concurrence of duodenal epithelioid stromal sarcoma, pulmonary chondromatous hamartoma, and nonfunctioning pancreatic islet cell tumor. A possible analogue of Carney's triad? ( 8060238 )
1994
38
Comparison of plasma pancreastatin and GAWK concentrations, presumed processing products of chromogranin A and B, in plasma of patients with pancreatic islet cell tumors. ( 8288164 )
1993
39
Surgical experience with pancreatic islet-cell tumors. ( 8105769 )
1993
40
Subcutaneous fat necrosis associated with pancreatic islet cell tumor. ( 1314524 )
1992
41
Islet amyloid polypeptide-producing pancreatic islet cell tumor. A clinical and biochemical characterization. ( 1326785 )
1992
42
Endoscopic ultrasonography in the diagnosis of pancreatic islet cell tumors. ( 1646897 )
1991
43
7B2, a possible marker for nonfunctioning pancreatic islet cell tumor. ( 1662184 )
1991
44
Non-functioning pancreatic islet cell tumor presenting with gastrointestinal hemorrhage. ( 1655645 )
1991
45
Pancreastatin producing cell line from human pancreatic islet cell tumor. ( 2159299 )
1990
46
Hyperinsulinism and hypoglycemia associated with pancreatic islet cell tumor in a ferret. ( 2537277 )
1989
47
The role of morphometry in predicting prognosis in pancreatic islet cell tumors. ( 2544252 )
1989
48
Pancreatic islet cell tumors metastatic to the liver: treatment by hepatic artery chemo-embolization. ( 2559021 )
1989
49
Use of long-acting somatostatin analog SMS 201-995 in patients with pancreatic islet cell tumors. ( 2537716 )
1989
50
Endoscopic retrograde cholangiopancreatography in pancreatic islet cell tumors. ( 2832244 )
1988

Variations for Pancreatic Islet Cell Tumors

Expression for Pancreatic Islet Cell Tumors

Search GEO for disease gene expression data for Pancreatic Islet Cell Tumors.

Pathways for Pancreatic Islet Cell Tumors

Pathways related to Pancreatic Islet Cell Tumors according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.86 CALCA GAST INS MEN1 NTS SST

GO Terms for Pancreatic Islet Cell Tumors

Cellular components related to Pancreatic Islet Cell Tumors according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.02 CALCA GAST INS NTS SST

Biological processes related to Pancreatic Islet Cell Tumors according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.5 MEN1 SST TSC2
2 cell-cell signaling GO:0007267 9.33 CALCA INS SST
3 response to heat GO:0009408 9.26 CALCA SST
4 cellular protein metabolic process GO:0044267 9.13 CALCA INS MEN1
5 positive regulation of vasodilation GO:0045909 8.62 CALCA INS

Molecular functions related to Pancreatic Islet Cell Tumors according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.92 CALCA GAST INS SST

Sources for Pancreatic Islet Cell Tumors

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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