MCID: PNC044
MIFTS: 61

Pancreatitis malady

Categories: Endocrine diseases, Genetic diseases, Rare diseases, Gastrointestinal diseases, Bone diseases, Immune diseases

Aliases & Classifications for Pancreatitis

Summaries for Pancreatitis

MedlinePlus : 41 the pancreas is a large gland behind the stomach and close to the first part of the small intestine. it secretes digestive juices into the small intestine through a tube called the pancreatic duct. the pancreas also releases the hormones insulin and glucagon into the bloodstream. pancreatitis is inflammation of the pancreas. it happens when digestive enzymes start digesting the pancreas itself. pancreatitis can be acute or chronic. either form is serious and can lead to complications. acute pancreatitis occurs suddenly and usually goes away in a few days with treatment. it is often caused by gallstones. common symptoms are severe pain in the upper abdomen, nausea, and vomiting. treatment is usually a few days in the hospital for intravenous (iv) fluids, antibiotics, and medicines to relieve pain. chronic pancreatitis does not heal or improve. it gets worse over time and leads to permanent damage. the most common cause is heavy alcohol use. other causes include cystic fibrosis and other inherited disorders, high levels of calcium or fats in the blood, some medicines, and autoimmune conditions. symptoms include nausea, vomiting, weight loss, and oily stools. treatment may also be a few days in the hospital for intravenous (iv) fluids, medicines to relieve pain, and nutritional support. after that, you may need to start taking enzymes and eat a special diet. it is also important to not smoke or drink alcohol. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Pancreatitis is related to gastritis and typhoid fever, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Pancreatitis is SPINK1 (Serine Peptidase Inhibitor, Kazal Type 1), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Pancreatic secretion. The drugs Secretin and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include pancreatic islet, pancreas and liver.

Wikipedia : 71 Pancreatitis is inflammation of the pancreas. The pancreas is a large organ behind the stomach that... more...

GeneReviews: NBK190101

Related Diseases for Pancreatitis

Diseases in the Pancreatitis family:

Pancreatitis, Hereditary Acute Pancreatitis
Prss1-Related Hereditary Pancreatitis Autoimmune Pancreatitis
Cftr-Related Hereditary Pancreatitis Ctrc-Related Hereditary Pancreatitis
Spink1-Related Hereditary Pancreatitis Autoimmune Pancreatitis Type 2
Autoimmune Pancreatitis Type 1 Recurrent Acute Pancreatitis

Diseases related to Pancreatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 996)
id Related Disease Score Top Affiliating Genes
1 gastritis 30.0 PRSS1 PRSS2
2 typhoid fever 29.4 CCK CFTR SST TMPRSS15
3 netherton syndrome 28.6 CCK CFTR CPA1 CTRC PNLIP PRSS1
4 short bowel syndrome 28.5 APOC2 CCK CFTR PNLIP SCT SST
5 pancreatic cancer 12.5
6 pancreatitis, hereditary 12.4
7 acute pancreatitis 12.3
8 pancreatic lipase deficiency 12.2
9 tropical calcific pancreatitis 12.2
10 autoimmune pancreatitis 12.2
11 pancreatic ductal adenocarcinoma 12.2
12 pancreatic ductal carcinoma 12.1
13 exocrine pancreatic insufficiency 12.1
14 renal-hepatic-pancreatic dysplasia 12.1
15 pancreatic agenesis and congenital heart defects 12.1
16 pancreatic neuroendocrine tumor 12.0
17 pancreatic mucinous cystadenoma 12.0
18 pancreatic cancer/melanoma syndrome 12.0
19 pancreatic and cerebellar agenesis 12.0
20 pancreatic agenesis 1 12.0
21 pancreatic cancer 4 12.0
22 recurrent acute pancreatitis 12.0
23 pancreatic serous cystadenoma 12.0
24 pancreatic agenesis 2 12.0
25 infantile-onset multisystem neurologic, endocrine, and pancreatic disease 12.0
26 exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis 11.9
27 pancreatic steatorrhea 11.9
28 renal-hepatic-pancreatic dysplasia 2 11.9
29 congenital pancreatic cyst 11.9
30 pancreatitis, pediatric 11.9
31 pancreatic cancer 1 11.9
32 pancreatic cancer 3 11.9
33 alcoholic pancreatitis 11.9
34 autoimmune pancreatitis type 1 11.9
35 pancreatic agenesis 11.9
36 renal-hepatic-pancreatic dysplasia 1 11.8
37 pancreatic cancer 2 11.8
38 pancreatic acinar cell adenocarcinoma 11.8
39 pancreatic somatostatinoma 11.8
40 non-functioning pancreatic endocrine tumor 11.8
41 pancreatic cholera 11.8
42 pancreatic endocrine carcinoma 11.8
43 pancreatic islet cell tumors 11.8
44 pancreatic gastrinoma 11.8
45 pancreatic solid pseudopapillary carcinoma 11.8
46 pancreatic intraductal papillary-mucinous neoplasm 11.8
47 pancreatic intraductal papillary-colloid carcinoma 11.8
48 pancreatic serous cystadenocarcinoma 11.7
49 pancreatic vasoactive intestinal peptide producing tumor 11.7
50 pancreatic cystadenoma 11.7

Graphical network of the top 20 diseases related to Pancreatitis:



Diseases related to Pancreatitis

Symptoms & Phenotypes for Pancreatitis

UMLS symptoms related to Pancreatitis:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, gastrointestinal gas

Drugs & Therapeutics for Pancreatitis

Drugs for Pancreatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 414)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Secretin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 108153-74-8
2
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
3
Clonidine Approved Phase 4 4205-90-7 2803
4
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Phase 1 84057-95-4 71273 175805
5
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
6
Tramadol Approved, Investigational Phase 4,Phase 2,Phase 3 27203-92-5 33741
7
Cefoperazone Approved Phase 4 62893-19-0 44185
8
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
9
Meropenem Approved, Investigational Phase 4,Phase 1,Phase 2 119478-56-7 64778 441130
10
Metronidazole Approved Phase 4 443-48-1 4173
11
Somatostatin Approved Phase 4,Phase 3 38916-34-6, 51110-01-1 53481605
12
Pancrelipase Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 53608-75-6
13
Diclofenac Approved, Vet_approved Phase 4,Phase 1 15307-86-5 3033
14
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3 59467-70-8 4192
15
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
16
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
17
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
18
Menthol Approved Phase 4 2216-51-5 16666
19
Octreotide Approved, Investigational Phase 4 83150-76-9 383414 6400441
20
Ceftazidime Approved Phase 4 78439-06-2 5481173
21
Glycerol Approved, Experimental Phase 4,Phase 3 56-81-5 753
22
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
23
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 2078-54-8 4943
24
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
25
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
26
Etomidate Approved Phase 4 33125-97-2 36339 667484
27
Meperidine Approved Phase 4 57-42-1 4058
28
Indomethacin Approved, Investigational Phase 4,Phase 3,Phase 2 53-86-1 3715
29
Azathioprine Approved Phase 4 446-86-6 2265
30
Thioguanine Approved Phase 4 154-42-7 2723601
31
Cilastatin Approved Phase 4 82009-34-5 5280454 6435415
32
Imipenem Approved Phase 4 74431-23-5 104838
33
Ketorolac Approved Phase 4,Phase 2,Phase 3 74103-06-3, 66635-83-4 3826
34
Etanercept Approved, Investigational Phase 4 185243-69-0
35 Pinaverium Approved Phase 4 59995-65-2
36
Leflunomide Approved, Investigational Phase 4 75706-12-6 3899
37
Prednisone Approved, Vet_approved Phase 4,Phase 1 53-03-2 5865
38
Cholecalciferol Approved, Nutraceutical Phase 4 67-97-0 6221 10883523 5280795
39
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
40
Resveratrol Experimental, Investigational Phase 4 501-36-0, 955365-80-7 24856436 445154
41 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
42 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
45 Fat Emulsions, Intravenous Phase 4
46 Parenteral Nutrition Solutions Phase 4
47 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
48 Soybean oil, phospholipid emulsion Phase 4
49 Adjuvants, Anesthesia Phase 4,Phase 3,Phase 2,Phase 1
50 Analgesics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 463)
id Name Status NCT ID Phase
1 Efficacy of Secretin MRCP in the Diagnosis and Follow up of Auto Immune Pancreatitis Unknown status NCT01845467 Phase 4
2 Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis Unknown status NCT01376817 Phase 4
3 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
4 Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis Unknown status NCT01992198 Phase 4
5 Peri-operative Expression Analysis of Pancreatic Stone Protein in a Surgical Study Population Unknown status NCT01258179 Phase 4
6 Prophylactic Pancreatic Duct Stent Placement After ESP of Major Papillary Tumors; Prospective, Randomized Study Unknown status NCT01737463 Phase 4
7 Evaluation of Pancreatic Tissue Penetration of Meronem® in the Prophylaxis of Septic Complications in Severe Pancreatitis Completed NCT00318994 Phase 4
8 Evaluation of the Digestive and Metabolic Utilisation of Dietary Protein in Patients With Chronic Pancreatitis Completed NCT00957151 Phase 4
9 Early Enteral Nutrition for Severe Acute Pancreatitis Completed NCT00995098 Phase 4
10 Activated Protein C in Severe Acute Pancreatitis Completed NCT01017107 Phase 4
11 Enteral Nutrition in Acute Pancreatitis Completed NCT01965873 Phase 4
12 Acute Pancreatitis and Acute Fluid Collections Completed NCT00786929 Phase 4
13 Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers Completed NCT00222092 Phase 4
14 Prospective Study of Efficacy of Intra-muscular Vitamin D3 in Tropical Calcific Pancreatitis Completed NCT00956839 Phase 4
15 Post ERCP Pancreatitis Prevention in Average Risk Patients Completed NCT01784445 Phase 4
16 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4
17 A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died Completed NCT00061438 Phase 4
18 Dexmedetomidine Versus Placebo in Endoscopic Retrograde Cholangiopancreatography (ERCP) Sedation Completed NCT01070680 Phase 4
19 Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant Completed NCT01186562 Phase 4
20 Enzyme Suppletion in Exocrine Pancreatic Dysfunction Completed NCT01430234 Phase 4
21 A Trial of 0.025 Wire Guided Cannulation Versus Current Practice 0.035 Wire Guided Cannulation Completed NCT01408264 Phase 4
22 Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube Completed NCT00999232 Phase 4
23 Prospective Study of Celiac Block Injection: 1 vs. 2 Completed NCT00583479 Phase 4
24 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
25 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4
26 Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients Completed NCT00560157 Phase 4
27 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4
28 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction Completed NCT00280709 Phase 4
29 Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction Completed NCT02909595 Phase 4
30 A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone Deficiency Completed NCT00455884 Phase 4
31 Thiopurine Induced Pancreatitis in IBD Patients Recruiting NCT02281799 Phase 4
32 Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP) Recruiting NCT02111707 Phase 4
33 Rectal Indomethacin to Prevent Post ESWL-pancreatitis Recruiting NCT02797067 Phase 4
34 Imipenem Prophylaxis in Patients With Acute Pancreatitis Recruiting NCT02897206 Phase 4
35 WallFlex Biliary Fully Covered (FC) Chronic Pancreatitis Study Recruiting NCT01543256 Phase 4
36 Treatment of Acute Pancreatitis With Ketorolac Recruiting NCT02885441 Phase 4
37 Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis Recruiting NCT02839356 Phase 4
38 Anti-inflammatory Therapy to Improve Outcomes After TPIAT Recruiting NCT02713997 Phase 4
39 Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy Recruiting NCT01642875 Phase 4
40 Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction Recruiting NCT02833103 Phase 4
41 Leflunomide for Maintenance of Remission in IgG4 Related Disease Recruiting NCT02703194 Phase 4
42 A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric Patients Active, not recruiting NCT02722057 Phase 4
43 COX-2 Inhibitor to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02964403 Phase 4
44 Oral Resveratrol to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02947932 Phase 4
45 Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal Not yet recruiting NCT03082469 Phase 4
46 A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02465138 Phase 4
47 Dexmedetomidine Hydrochloride in the Prevention of Organ Failure Following Severe Acute Pancreatitis Not yet recruiting NCT02691598 Phase 4
48 Ulinastatin in Severe Acute Pancreatitis Suspended NCT01132521 Phase 4
49 Diclofenac for the Prevention of Post-ERCP Pancreatitis in Higher Risk Patients Terminated NCT00428025 Phase 4
50 Rectal Indomethacin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis in High Risk Patients Terminated NCT00820612 Phase 4

Search NIH Clinical Center for Pancreatitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: pancreatitis

Genetic Tests for Pancreatitis

Genetic tests related to Pancreatitis:

id Genetic test Affiliating Genes
1 Pancreatitis 29

Anatomical Context for Pancreatitis

MalaCards organs/tissues related to Pancreatitis:

39
Pancreatic Islet, Pancreas, Liver, Testes, Endothelial, Lung, Kidney

Publications for Pancreatitis

Articles related to Pancreatitis:

(show top 50) (show all 16884)
id Title Authors Year
1
Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism. ( 28260082 )
2017
2
Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature. ( 28507728 )
2017
3
Effectiveness of Guideline-recommended Cholecystectomy to Prevent Recurrent Pancreatitis. ( 28071655 )
2017
4
The critical role and potential target of the autotaxin/lysophosphatidate axis in pancreatic cancer. ( 28347252 )
2017
5
The Role of Gut-brain Axis in Regulating Glucose Metabolism After Acute Pancreatitis. ( 28055028 )
2017
6
Duodenal gastrointestinal stromal tumor presenting as pancreatic head mass - a case report. ( 28523328 )
2017
7
Corrigendum to "Beneficial effects of 5-fluorouracil and heparin-based portal infusion chemotherapy combined with mitomycin C and cisplatin after curative resection of pancreatic cancer" [Pancreatology 10 (2010) 250-258]. ( 28089307 )
2017
8
Severe Hypertriglyceridemia Causing Pancreatitis in a Child with New-onset Type-I Diabetes Mellitus Presenting with Diabetic Ketoacidosis. ( 28400692 )
2017
9
Evaluation of Prognostic Immune Signatures in Patients with Breast, Colorectal and Pancreatic Cancer Receiving Chemotherapy. ( 28373465 )
2017
10
Unusual Presentation of Relapse in Neuroblastoma: Pancreatic Metastases Detected by 123I-MIBG Scintigraphy. ( 28525458 )
2017
11
Chronic Gastrointestinal Dysmotility and Pain Following Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis. ( 28083839 )
2017
12
Adipose Triglyceride Lipase (ATGL) Expression Is Associated with Adiposity and Tumor Stromal Proliferation in Patients with Pancreatic Ductal Adenocarcinoma. ( 28179319 )
2017
13
Percutaneous Irreversible Electroporation for Ablation of Locally Advanced Pancreatic Cancer: Experience From a Chinese Institution. ( 28085755 )
2017
14
Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4. ( 28188630 )
2017
15
Circulating microRNA 216 as a Marker for the Early Identification of Severe Acute Pancreatitis. ( 28183420 )
2017
16
Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions. ( 28057438 )
2017
17
Towards reducing the risk of new onset diabetes after pancreatitis. ( 28079345 )
2017
18
Growth rate of small pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: results from an endoscopic ultrasound based cohort study. ( 27975336 )
2017
19
Reply to the letter regarding "early dual drainage combining transpapillary endotherapy and percutaneous catheter drainage in patients with pancreatic fistula associated with severe acute pancreatitis". ( 28089101 )
2017
20
Interleukin-9 Promotes Pancreatic Cancer Cells Proliferation and Migration via the miR-200a/Beta-Catenin Axis. ( 28349057 )
2017
21
Downregulation of the N-myc downstream regulated gene 1 is related to enhanced proliferation, invasion and migration of pancreatic cancer. ( 28075464 )
2017
22
The Diagnostic Usefulness of Serum Total Bile Acid Concentrations in the Early Phase of Acute Pancreatitis of Varied Etiologies. ( 28067818 )
2017
23
Overexpressions of miR-212 are associated with poor prognosis of patients with pancreatic ductal adenocarcinoma. ( 27814273 )
2017
24
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. ( 28071719 )
2017
25
Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma. ( 28062705 )
2017
26
Autoimmune Pancreatitis Complicated With Pancreatic Ascites, Pancreatic Ductal Leakage, and Multiple Pseudocyst. ( 27977636 )
2017
27
Pancreatic neuroendocrine tumor with metastasis to the spleen: a case report. ( 28068959 )
2017
28
Targeted inhibition of pancreatic acinar cell calcineurin is a novel strategy to prevent post-ERCP pancreatitis. ( 28090570 )
2017
29
Reproductive factors, exogenous hormone use, and risk of pancreatic cancer in postmenopausal women. ( 28521283 )
2017
30
SIRT1 promotes the proliferation and metastasis of human pancreatic cancer cells. ( 28351313 )
2017
31
Hypertriglyceridemia and Pancreatitis-New Evidence That Less Is More-Reply. ( 28460108 )
2017
32
CTRC gene polymorphism (p.G60=; c.180 Ca88>a88T) in acute pancreatitis. ( 28095786 )
2017
33
Emphysematous Cholecystitis in a patient with Metastatic Pancreatic Neuroendocrine Tumour. ( 28062742 )
2017
34
Endoscopic ultrasound-guided ethanol ablation therapy for pancreatic insulinoma: an unusual strategy. ( 28458908 )
2017
35
Abdominal paracentesis drainage improves tolerance of enteral nutrition in acute pancreatitis: a randomized controlled trial. ( 28050922 )
2017
36
Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts. ( 28526679 )
2017
37
Targeted Stroma in Pancreatic Cancer: Promises and Failures of Target Therapies. ( 28083912 )
2017
38
Increased semaphorin 3c expression promotes tumor growth and metastasis in pancreatic ductal adenocarcinoma by activating the ERK1/2 signaling pathway. ( 28315433 )
2017
39
Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma. ( 28260012 )
2017
40
Downstaging in Stage IV Pancreatic Cancer: A New Population Eligible for Surgery? ( 28516291 )
2017
41
The Clinical Significance of miR-34a in Pancreatic Ductal Carcinoma and Associated Molecular and Cellular Mechanisms. ( 27458977 )
2017
42
DPC4 gene expression in primary pancreatic ductal adenocarcinoma: relationship with CT characteristics. ( 28339284 )
2017
43
Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-I_B/MMP-9 signaling pathway. ( 28088520 )
2017
44
Cancer cell chemokines direct chemotaxis of activated stellate cells in pancreatic ductal adenocarcinoma. ( 28092365 )
2017
45
MicroRNAa89296 targets AKT2 in pancreatic cancer and functions as a potential tumor suppressor. ( 28534950 )
2017
46
Impact of Concurrent Medication Use on Pancreatic Cancer Survival-SEER-Medicare Analysis. ( 28079594 )
2017
47
A Rare Cause of Recurrent Acute Pancreatitis in a Child: Isovaleric Acidemia with Novel Mutation. ( 28401058 )
2017
48
Hepatobiliary and Pancreatic: A unique case of HPV related metastatic Schneiderian carcinoma presenting as polycystic liver disease. ( 28052462 )
2017
49
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer. ( 28092682 )
2017
50
CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion. ( 28242758 )
2017

Variations for Pancreatitis

Copy number variations for Pancreatitis from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 194974 5 147184338 147191453 Deletion SPINK1 Pancreatitis
2 220321 7 137300000 142800000 Triplication PRSS1 Pancreatitis
3 220322 7 137300000 142800000 Triplication PRSS2 Pancreatitis
4 221070 7 142136892 142140501 Triplication PRSS1 Pancreatitis
5 221298 7 142800000 147500000 Triplication PRSS1 Pancreatitis

Expression for Pancreatitis

Search GEO for disease gene expression data for Pancreatitis.

GO Terms for Pancreatitis

Cellular components related to Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 APOC2 CCK CPA1 CPB1 LPL MUC4
2 extracellular region GO:0005576 9.5 APOC2 CCK CPA1 CPB1 CTRC LPL
3 very-low-density lipoprotein particle GO:0034361 9.26 APOC2 LPL
4 chylomicron GO:0042627 9.16 APOC2 LPL

Biological processes related to Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.8 CPA1 CPB1 CTRC PRSS1 PRSS2 TMPRSS15
2 digestion GO:0007586 9.54 PRSS1 PRSS2 SST
3 cobalamin metabolic process GO:0009235 9.46 CTRC PRSS1
4 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.43 LPL PLA2G2A
5 retinoid metabolic process GO:0001523 9.43 APOC2 LPL PNLIP
6 chylomicron remodeling GO:0034371 9.4 APOC2 LPL
7 very-low-density lipoprotein particle remodeling GO:0034372 9.16 APOC2 LPL
8 antimicrobial humoral response GO:0019730 9.13 PLA2G2A PRSS2 REG3A
9 lipid catabolic process GO:0016042 8.92 APOC2 LPL PLA2G2A PNLIP

Molecular functions related to Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.56 CTRC PRSS1 PRSS2 TMPRSS15
2 hormone activity GO:0005179 9.5 CCK SCT SST
3 serine-type peptidase activity GO:0008236 9.46 CTRC PRSS1 PRSS2 TMPRSS15
4 peptidase activity GO:0008233 9.43 CPA1 CPB1 CTRC PRSS1 PRSS2 TMPRSS15
5 triglyceride lipase activity GO:0004806 9.37 LPL PNLIP
6 hydrolase activity GO:0016787 9.32 CFTR CPA1 CPB1 CTRC LPL PLA2G2A

Sources for Pancreatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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