MCID: PNC044
MIFTS: 60

Pancreatitis

Categories: Endocrine diseases, Genetic diseases, Rare diseases, Gastrointestinal diseases, Bone diseases, Immune diseases

Aliases & Classifications for Pancreatitis

Summaries for Pancreatitis

MedlinePlus : 41 the pancreas is a large gland behind the stomach and close to the first part of the small intestine. it secretes digestive juices into the small intestine through a tube called the pancreatic duct. the pancreas also releases the hormones insulin and glucagon into the bloodstream. pancreatitis is inflammation of the pancreas. it happens when digestive enzymes start digesting the pancreas itself. pancreatitis can be acute or chronic. either form is serious and can lead to complications. acute pancreatitis occurs suddenly and usually goes away in a few days with treatment. it is often caused by gallstones. common symptoms are severe pain in the upper abdomen, nausea, and vomiting. treatment is usually a few days in the hospital for intravenous (iv) fluids, antibiotics, and medicines to relieve pain. chronic pancreatitis does not heal or improve. it gets worse over time and leads to permanent damage. the most common cause is heavy alcohol use. other causes include cystic fibrosis and other inherited disorders, high levels of calcium or fats in the blood, some medicines, and autoimmune conditions. symptoms include nausea, vomiting, weight loss, and oily stools. treatment may also be a few days in the hospital for intravenous (iv) fluids, medicines to relieve pain, and nutritional support. after that, you may need to start taking enzymes and eat a special diet. it is also important to not smoke or drink alcohol. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Pancreatitis is related to tropical calcific pancreatitis and netherton syndrome, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Pancreatitis is SPINK1 (Serine Peptidase Inhibitor, Kazal Type 1), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Pancreatic secretion. The drugs Secretin and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include pancreatic islet, pancreas and liver, and related phenotype is homeostasis/metabolism.

Wikipedia : 72 Pancreatitis is inflammation of the pancreas. The pancreas is a large organ behind the stomach that... more...

GeneReviews: NBK190101

Related Diseases for Pancreatitis

Diseases in the Pancreatitis family:

Pancreatitis, Hereditary Acute Pancreatitis
Prss1-Related Hereditary Pancreatitis Autoimmune Pancreatitis
Cftr-Related Hereditary Pancreatitis Ctrc-Related Hereditary Pancreatitis
Spink1-Related Hereditary Pancreatitis Autoimmune Pancreatitis Type 2
Autoimmune Pancreatitis Type 1 Recurrent Acute Pancreatitis

Diseases related to Pancreatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1009)
id Related Disease Score Top Affiliating Genes
1 tropical calcific pancreatitis 30.2 APOC2 CASR CCK CFTR CPA1 CTRC
2 netherton syndrome 29.5 CTRC PRSS1 PRSS2 REG1A SPINK1
3 typhoid fever 29.4 CCK SST TMPRSS15
4 cryoglobulinemia 25.6 APOC2 CCK CPB1 LPL PLA2G2A PNLIP
5 pancreatic cancer 12.5
6 pancreatitis, hereditary 12.4
7 pancreatic lipase deficiency 12.3
8 acute pancreatitis 12.3
9 autoimmune pancreatitis 12.2
10 pancreatic ductal adenocarcinoma 12.2
11 pancreatic ductal carcinoma 12.1
12 exocrine pancreatic insufficiency 12.1
13 renal-hepatic-pancreatic dysplasia 12.1
14 pancreatic agenesis and congenital heart defects 12.1
15 pancreatic neuroendocrine tumor 12.0
16 pancreatic cancer/melanoma syndrome 12.0
17 pancreatic cancer 4 12.0
18 pancreatic and cerebellar agenesis 12.0
19 pancreatic mucinous cystadenoma 12.0
20 recurrent acute pancreatitis 11.9
21 pancreatic agenesis 2 11.9
22 pancreatic agenesis 1 11.9
23 pancreatic serous cystadenoma 11.9
24 exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis 11.9
25 infantile-onset multisystem neurologic, endocrine, and pancreatic disease 11.9
26 pancreatic steatorrhea 11.9
27 renal-hepatic-pancreatic dysplasia 2 11.9
28 congenital pancreatic cyst 11.9
29 pancreatitis, pediatric 11.9
30 pancreatic cancer 1 11.9
31 pancreatic cancer 3 11.9
32 autoimmune pancreatitis type 1 11.9
33 pancreatic cancer 2 11.8
34 pancreatic acinar cell adenocarcinoma 11.8
35 alcoholic pancreatitis 11.8
36 pancreatic agenesis 11.8
37 pancreatic somatostatinoma 11.8
38 renal-hepatic-pancreatic dysplasia 1 11.8
39 non-functioning pancreatic endocrine tumor 11.8
40 pancreatic solid pseudopapillary carcinoma 11.8
41 pancreatic cholera 11.8
42 pancreatic endocrine carcinoma 11.8
43 pancreatic gastrinoma 11.8
44 pancreatic cystadenoma 11.7
45 pancreatic intraductal papillary-mucinous neoplasm 11.7
46 pancreatic cystadenocarcinoma 11.7
47 pancreatic intraductal papillary-colloid carcinoma 11.7
48 autoimmune pancreatitis type 2 11.7
49 pancreatic serous cystadenocarcinoma 11.7
50 pancreatic vasoactive intestinal peptide producing tumor 11.7

Graphical network of the top 20 diseases related to Pancreatitis:



Diseases related to Pancreatitis

Symptoms & Phenotypes for Pancreatitis

UMLS symptoms related to Pancreatitis:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, gastrointestinal gas

MGI Mouse Phenotypes related to Pancreatitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.4 APOC2 CASR CCK CFTR LPL PNLIP

Drugs & Therapeutics for Pancreatitis

Drugs for Pancreatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 424)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Secretin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 108153-74-8
2
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
3
Clonidine Approved Phase 4 4205-90-7 2803
4
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Phase 1 84057-95-4 71273 175805
5
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
6
Tramadol Approved, Investigational Phase 4,Phase 3,Phase 2 27203-92-5 33741
7
Cefoperazone Approved Phase 4 62893-19-0 44185
8
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
9
Meropenem Approved, Investigational Phase 4,Phase 1,Phase 2 119478-56-7 64778 441130
10
Metronidazole Approved Phase 4 443-48-1 4173
11
Somatostatin Approved Phase 4,Phase 3 38916-34-6, 51110-01-1 53481605
12
Pancrelipase Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 53608-75-6
13
Diclofenac Approved, Vet_approved Phase 4,Phase 1 15307-86-5 3033
14
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3 59467-70-8 4192
15
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
16 Racepinephrine Approved Phase 4
17
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
18
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
19
Menthol Approved Phase 4 2216-51-5 16666
20
Indomethacin Approved, Investigational Phase 4,Phase 3,Phase 2 53-86-1 3715
21
Cilastatin Approved Phase 4 82009-34-5 5280454 6435415
22
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
23
Protein C Approved Phase 4,Phase 1,Phase 2
24
Ketorolac Approved Phase 4,Phase 3,Phase 2 74103-06-3, 66635-83-4 3826
25
Octreotide Approved, Investigational Phase 4 83150-76-9 383414 6400441
26
Ceftazidime Approved Phase 4 78439-06-2, 72558-82-8 5481173
27
Glycerol Approved, Investigational Phase 4,Phase 3 56-81-5 753
28
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
29
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 2078-54-8 4943
30
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
31
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
32
Etomidate Approved Phase 4 33125-97-2 36339 667484
33
Meperidine Approved Phase 4 57-42-1 4058
34
Prednisone Approved, Vet_approved Phase 4,Phase 1 53-03-2 5865
35
Azathioprine Approved Phase 4 446-86-6 2265
36
Thioguanine Approved Phase 4 154-42-7 2723601
37
Etanercept Approved, Investigational Phase 4 185243-69-0
38 Pinaverium Approved Phase 4 59995-65-2
39
Thrombin Approved Phase 4
40
Leflunomide Approved, Investigational Phase 4 75706-12-6 3899
41
Cholecalciferol Approved, Nutraceutical Phase 4 67-97-0 6221 10883523 5280795
42
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
43
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
44 Nefopam Investigational Phase 4 13669-70-0
45
Resveratrol Experimental, Investigational Phase 4 501-36-0 445154
46 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
47 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
48 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
49 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
50 Fat Emulsions, Intravenous Phase 4

Interventional clinical trials:

(show top 50) (show all 484)

id Name Status NCT ID Phase Drugs
1 Efficacy of Secretin MRCP in the Diagnosis and Follow up of Auto Immune Pancreatitis Unknown status NCT01845467 Phase 4
2 Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis Unknown status NCT01376817 Phase 4 Fat emulsion with MCT, LCT, olive oil and omega 3 fatty acids;Fat emulsion with MCT and LCT
3 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
4 Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis Unknown status NCT01992198 Phase 4 cefoperazone + metronidazole;Somatostatin;Meropenem
5 Prophylactic Pancreatic Duct Stent Placement After ESP of Major Papillary Tumors; Prospective, Randomized Study Unknown status NCT01737463 Phase 4
6 Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP) Completed NCT02111707 Phase 4 Rectal indomethacin 100mg one time before or after ERCP
7 Evaluation of Pancreatic Tissue Penetration of Meronem® in the Prophylaxis of Septic Complications in Severe Pancreatitis Completed NCT00318994 Phase 4 Meropenem
8 Evaluation of the Digestive and Metabolic Utilisation of Dietary Protein in Patients With Chronic Pancreatitis Completed NCT00957151 Phase 4 Creon
9 Early Enteral Nutrition for Severe Acute Pancreatitis Completed NCT00995098 Phase 4
10 Imipenem Prophylaxis in Patients With Acute Pancreatitis Completed NCT02897206 Phase 4 Imipenem;Placebo
11 Activated Protein C in Severe Acute Pancreatitis Completed NCT01017107 Phase 4 Activated protein C
12 Enteral Nutrition in Acute Pancreatitis Completed NCT01965873 Phase 4
13 Acute Pancreatitis and Acute Fluid Collections Completed NCT00786929 Phase 4 Conservative treatment
14 Treatment of Acute Pancreatitis With Ketorolac Completed NCT02885441 Phase 4 Ketorolac;Placebo
15 Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers Completed NCT00222092 Phase 4
16 Prospective Study of Efficacy of Intra-muscular Vitamin D3 in Tropical Calcific Pancreatitis Completed NCT00956839 Phase 4 Vitamin D3 (Cholecalciferol)
17 Post ERCP Pancreatitis Prevention in Average Risk Patients Completed NCT01784445 Phase 4 Ceftazidime
18 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4 early enteral nutrition;Delayed enteral nutrition
19 A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died Completed NCT00061438 Phase 4 meropenem
20 Dexmedetomidine Versus Placebo in Endoscopic Retrograde Cholangiopancreatography (ERCP) Sedation Completed NCT01070680 Phase 4 Precedex;sodium chlorid 0,9%
21 Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant Completed NCT01186562 Phase 4 Sitagliptin;Placebo
22 Enzyme Suppletion in Exocrine Pancreatic Dysfunction Completed NCT01430234 Phase 4 Panzytrat 25.000 FIP-E units of Lipase
23 A Trial of 0.025 Wire Guided Cannulation Versus Current Practice 0.035 Wire Guided Cannulation Completed NCT01408264 Phase 4
24 Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube Completed NCT00999232 Phase 4 Erythromycin;Placebo
25 Prospective Study of Celiac Block Injection: 1 vs. 2 Completed NCT00583479 Phase 4
26 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
27 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
28 Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients Completed NCT00560157 Phase 4
29 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
30 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction Completed NCT00280709 Phase 4
31 Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction Completed NCT02909595 Phase 4
32 A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone Deficiency Completed NCT00455884 Phase 4
33 Thiopurine Induced Pancreatitis in IBD Patients Recruiting NCT02281799 Phase 4 Azathioprine
34 Rectal Indomethacin to Prevent Post ESWL-pancreatitis Recruiting NCT02797067 Phase 4 indomethacin suppository;glycerin suppository
35 WallFlex Biliary Fully Covered (FC) Chronic Pancreatitis Study Recruiting NCT01543256 Phase 4
36 Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis Recruiting NCT02839356 Phase 4 epinephrine;normal saline
37 Anti-inflammatory Therapy to Improve Outcomes After TPIAT Recruiting NCT02713997 Phase 4 etanercept;Alpha 1-Antitrypsin
38 Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy Recruiting NCT01642875 Phase 4
39 Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction Recruiting NCT02833103 Phase 4 Danshu Capsules;Pinaverium Bromide
40 Intraductal Secretin Stimulation Test: What Is the Proper Collection Time? Recruiting NCT03263481 Phase 4 Human Secretin for injection 16 mcg
41 The Effect of Application of TachoSil® in Pancreatoduodenectomy Recruiting NCT03269955 Phase 4 Fibrinogen/thrombin-coated collagen patch
42 Leflunomide for Maintenance of Remission in IgG4 Related Disease Recruiting NCT02703194 Phase 4 Prednisone;Leflunomide
43 COX-2 Inhibitor to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02964403 Phase 4 Cox-2;Indomethacin
44 Oral Resveratrol to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02947932 Phase 4 Resveratrol;Indomethacin
45 Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal Not yet recruiting NCT03082469 Phase 4
46 A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis Not yet recruiting NCT02465138 Phase 4 Ketorolac;Placebo
47 Dexmedetomidine Hydrochloride in the Prevention of Organ Failure Following Severe Acute Pancreatitis Not yet recruiting NCT02691598 Phase 4 Infusion
48 Ulinastatin in Severe Acute Pancreatitis Suspended NCT01132521 Phase 4 ulinastatin;placebo
49 Diclofenac for the Prevention of Post-ERCP Pancreatitis in Higher Risk Patients Terminated NCT00428025 Phase 4 diclofenac;placebo
50 Rectal Indomethacin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis in High Risk Patients Terminated NCT00820612 Phase 4 Indomethacin

Search NIH Clinical Center for Pancreatitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: pancreatitis

Genetic Tests for Pancreatitis

Genetic tests related to Pancreatitis:

id Genetic test Affiliating Genes
1 Pancreatitis 29

Anatomical Context for Pancreatitis

MalaCards organs/tissues related to Pancreatitis:

39
Pancreatic Islet, Pancreas, Liver, Testes, Endothelial, Lung, T Cells

Publications for Pancreatitis

Articles related to Pancreatitis:

(show top 50) (show all 17295)
id Title Authors Year
1
Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature. ( 28507728 )
2017
2
Expression and Prognostic Value of Indoleamine 2,3-dioxygenase in Pancreatic Cancer. ( 28303855 )
2017
3
Acute Pancreatitis with Splenic Infarction as Early Postoperative Complication following Laparoscopic Sleeve Gastrectomy. ( 28487807 )
2017
4
A rare cause of recurrent acute pancreatitis: duodenum intussusception by a fenestrated duodenal web. ( 28342893 )
2017
5
The anti-inflammatory effect of hydrogen sulphide on acute necrotizing pancreatitis in rats. ( 28944326 )
2017
6
The Diagnostic Usefulness of Serum Total Bile Acid Concentrations in the Early Phase of Acute Pancreatitis of Varied Etiologies. ( 28067818 )
2017
7
DEK protein overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma. ( 27959420 )
2017
8
Eosinophilic Pancreatitis: A Rare Cause of Recurrent Acute Pancreatitis. ( 28611564 )
2017
9
Selective cytotoxicity of vanadium complexes on human pancreatic ductal adenocarcinoma cell line by inducing necroptosis, apoptosis and mitotic catastrophe process. ( 28947974 )
2017
10
Correlations Between LP-PLA2 Gene Polymorphisms and Susceptibility and Severity of Acute Pancreatitis in a Chinese Population. ( 28332853 )
2017
11
Serum Concentrations of Angiopoietin-2 and Soluble fms-Like Tyrosine Kinase 1 (sFlt-1) Are Associated with Coagulopathy among Patients with Acute Pancreatitis. ( 28368336 )
2017
12
Human pancreatic acinar cells: proteomic characterization, physiologic responses, and organellar disorders in ex vivo pancreatitis. ( 28935577 )
2017
13
Hepatobiliary and Pancreatic: A rare case of a well-differentiated neuroendocrine tumor in the bile duct with spontaneous regression diagnosed by EUS-FNA. ( 28052461 )
2017
14
Preclinical Rationale for the Phase III Trials in Metastatic Pancreatic Cancer: Is Wishful Thinking Clouding Successful Drug Development for Pancreatic Cancer? ( 28085753 )
2017
15
A rare etiology of idiopathic recurrent acute pancreatitis. ( 28355653 )
2017
16
Aquaporin 3 facilitates tumor growth in pancreatic cancer by modulating mTOR signaling. ( 28377226 )
2017
17
Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. ( 28193492 )
2017
18
Pancreatic Panniculitis Sans Pancreatitis in a Patient with Diabetic Ketoacidosis. ( 28733691 )
2017
19
MicroRNA-7 functions as a tumor-suppressor gene by regulating ILF2 in pancreatic carcinoma. ( 28259961 )
2017
20
Acute suppurative cholangitis due to an impacted pancreatic stone: a rare adverse event in the setting of chronic calcifiedA pancreatitis. ( 28842170 )
2017
21
Successful Management of Pancreatic Kaposiform Hemangioendothelioma With Sirolimus: Case Report and Literature Review. ( 28426496 )
2017
22
Board Review Vignette: PPP Syndrome: Pancreatitis, Panniculitis, Polyarthritis. ( 28741613 )
2017
23
CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion. ( 28242758 )
2017
24
MicroRNAa89296 targets AKT2 in pancreatic cancer and functions as a potential tumor suppressor. ( 28534950 )
2017
25
Prognostic value of WHO grade in pancreatic neuro-endocrine tumors in Multiple Endocrine Neoplasia type 1: Results from the DutchMEN1 Study Group. ( 28811081 )
2017
26
Pancreatic Lymphangioma: A Diagnostic and Treatment Dilemma. ( 28738930 )
2017
27
Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions. ( 28057438 )
2017
28
The prevalence of underweight is increased in chronic pancreatitis outpatients and associates with reduced life quality. ( 28935139 )
2017
29
Development and Validation of a Nomogram for Predicting Survival in Patients with Advanced Pancreatic Ductal Adenocarcinoma. ( 28912447 )
2017
30
ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca(2+)/RhoA pathway. ( 28518134 )
2017
31
A Rare Case of Pancreas Divisum Accompanied by Acute Pancreatitis Following Endoscopic Hemostasis for Duodenal Ulcer Bleeding. ( 28449428 )
2017
32
Acinar cell carcinoma of the pancreas presenting as diffuse pancreatic enlargement: Two case reports and literature review. ( 28930825 )
2017
33
Case report: Irreversible electroporation for locally advanced pancreatic cancer. ( 28941969 )
2017
34
Percutaneous Irreversible Electroporation for Pancreatic VIPoma: A Case Report. ( 27977628 )
2017
35
Exocrine pancreatic insufficiency is common in people living with HIV on effective antiretroviral therapy. ( 28838283 )
2017
36
Addison's Disease Mimicking as Acute Pancreatitis: A Case Report. ( 28571196 )
2017
37
Combined 18F-FDG PET/CT and 68Ga DOTATATE PET/CT "Superscan" in Metastatic Pancreatic Neuroendocrine Tumor. ( 27997429 )
2017
38
Pancreatic Neuroendocrine Tumor Abnormally Secreting Procalcitonin. ( 27977635 )
2017
39
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis. ( 28086938 )
2017
40
Combined Analyses of hENT1, TS, and DPD Predict Outcomes of Borderline-resectable Pancreatic Cancer. ( 28476815 )
2017
41
MiR-143 Targeting TAK1 Attenuates Pancreatic Ductal Adenocarcinoma Progression via MAPK and NF-I_B Pathway In Vitro. ( 28194669 )
2017
42
Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers. ( 27996162 )
2017
43
The Clinical Significance of miR-34a in Pancreatic Ductal Carcinoma and Associated Molecular and Cellular Mechanisms. ( 27458977 )
2017
44
Prognostic relevance of lactate dehydrogenase in advanced pancreatic ductal adenocarcinoma patients. ( 28056913 )
2017
45
Autoimmune Pancreatitis Complicated With Pancreatic Ascites, Pancreatic Ductal Leakage, and Multiple Pseudocyst. ( 27977636 )
2017
46
Expression of key mTOR pathway components in pancreatic ductal adenocarcinoma: A multicenter study for clinicopathologic and prognostic significance. ( 28279716 )
2017
47
Sarcoidosis mimicking metastatic progression of pancreatic neuroendocrine tumor: A case report. ( 28658123 )
2017
48
Ku70 inhibits gemcitabine-induced DNA damage and pancreatic cancer cell apoptosis. ( 28153717 )
2017
49
Corrigendum to "Beneficial effects of 5-fluorouracil and heparin-based portal infusion chemotherapy combined with mitomycin C and cisplatin after curative resection of pancreatic cancer" [Pancreatology 10 (2010) 250-258]. ( 28089307 )
2017
50
Current Strategies for Detection and Treatment of Recurrence of Pancreatic Ductal Adenocarcinoma After Resection: A Nationwide Survey. ( 28902799 )
2017

Variations for Pancreatitis

Copy number variations for Pancreatitis from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 194974 5 147184338 147191453 Deletion SPINK1 Pancreatitis
2 220321 7 137300000 142800000 Triplication PRSS1 Pancreatitis
3 220322 7 137300000 142800000 Triplication PRSS2 Pancreatitis
4 221070 7 142136892 142140501 Triplication PRSS1 Pancreatitis
5 221298 7 142800000 147500000 Triplication PRSS1 Pancreatitis

Expression for Pancreatitis

Search GEO for disease gene expression data for Pancreatitis.

GO Terms for Pancreatitis

Cellular components related to Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 APOC2 CCK CPA1 CPB1 CTRC LPL
2 extracellular space GO:0005615 9.4 APOC2 CCK CPA1 CPB1 LPL PLA2G2A
3 very-low-density lipoprotein particle GO:0034361 9.26 APOC2 LPL
4 chylomicron GO:0042627 9.16 APOC2 LPL

Biological processes related to Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.8 CPA1 CPB1 CTRC PRSS1 PRSS2 TMPRSS15
2 digestion GO:0007586 9.54 PRSS1 PRSS2 SST
3 cobalamin metabolic process GO:0009235 9.46 CTRC PRSS1
4 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.43 LPL PLA2G2A
5 retinoid metabolic process GO:0001523 9.43 APOC2 LPL PNLIP
6 chylomicron remodeling GO:0034371 9.4 APOC2 LPL
7 very-low-density lipoprotein particle remodeling GO:0034372 9.16 APOC2 LPL
8 antimicrobial humoral response GO:0019730 9.13 PLA2G2A PRSS2 REG3A
9 lipid catabolic process GO:0016042 8.92 APOC2 LPL PLA2G2A PNLIP

Molecular functions related to Pancreatitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.56 CTRC PRSS1 PRSS2 TMPRSS15
2 hormone activity GO:0005179 9.5 CCK SCT SST
3 serine-type peptidase activity GO:0008236 9.46 CTRC PRSS1 PRSS2 TMPRSS15
4 peptidase activity GO:0008233 9.43 CPA1 CPB1 CTRC PRSS1 PRSS2 TMPRSS15
5 triglyceride lipase activity GO:0004806 9.37 LPL PNLIP
6 hydrolase activity GO:0016787 9.32 CFTR CPA1 CPB1 CTRC LPL PLA2G2A

Sources for Pancreatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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