MCID: PNC019
MIFTS: 32

Pancreatoblastoma malady

Categories: Rare diseases, Gastrointestinal diseases, Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatoblastoma

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10 via Orphanet, 38MeSH, 39MESH via Orphanet, 44NCIt, 47NIH Rare Diseases, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Pancreatoblastoma:

Name: Pancreatoblastoma 11 47 53 38 13 67

Characteristics:

Orphanet epidemiological data:

53
pancreatoblastoma:
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe),<1/1000000 (Worldwide); Age of onset: Adult,Childhood; Age of death: adult,early childhood,late childhood

Classifications:



External Ids:

Disease Ontology11 DOID:6823
MeSH38 C537162
NCIt44 C4265
Orphanet53 ORPHA677
SNOMED-CT61 189814006, 53618008
MESH via Orphanet39 C537162
UMLS via Orphanet68 C0334489
ICD10 via Orphanet30 C25.1

Summaries for Pancreatoblastoma

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Wikipedia:70 Pancreatoblastoma is a rare type of pancreatic cancer. more...

MalaCards based summary: Pancreatoblastoma is related to childhood teratocarcinoma of the testis and lassueur-graham-little syndrome, and has symptoms including Array, Array and Array. An important gene associated with Pancreatoblastoma is AFP (Alpha Fetoprotein), and among its related pathways is Glucocorticoid receptor regulatory network. Affiliated tissues include pancreas, liver and brain.

Related Diseases for Pancreatoblastoma

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Diseases related to Pancreatoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1childhood teratocarcinoma of the testis10.6AFP, SERPINA1
2lassueur-graham-little syndrome10.5AFP, SERPINA1
3hyperuricemia10.5AFP, SERPINA1
4paranasal sinus cancer10.5AFP, SYP
5epithelial predominant pulmonary blastoma10.5AFP, SYP
6gastric teratoma10.5AFP, SYP
7adult teratoma10.5AFP, SYP
8prostate small cell carcinoma10.5AFP, SYP
9ovarian germ cell teratoma10.5AFP, CHGA
10spontaneous tension pneumothorax10.5AFP, SYP
11female reproductive endometrioid cancer10.5AFP, SYP
12colonic disease10.5AFP, SERPINA1
13testicular gonadoblastoma10.5AFP, SYP
14adult pineal parenchymal tumor10.5AFP, CHGA
15large cell medulloblastoma10.5AFP, SYP
16ovary serous adenocarcinoma10.5AFP, CHGA
17focal epithelial hyperplasia10.4AFP, SERPINA1
18spindle cell synovial sarcoma10.4AFP, SERPINA1
19nodular tenosynovitis10.4AFP, CHGA
20vibratory urticaria10.4AFP, SYP
21nephrogenic adenofibroma10.4AFP, SYP
22ovary mixed epithelial carcinoma10.4CHGA, SYP
23esophagus small cell carcinoma10.4CHGA, SYP
24lice infestation10.4CHGA, SYP
25apocrine adenocarcinoma10.4AFP, CHGA
26microglandular adenosis of breast10.4CHGA, SYP
27clear cell adenoma10.4CHGA, SYP
28punctate porokeratosis10.4CHGA, SYP
29osteoblastoma10.4CHGA, SYP
30urethra adenocarcinoma10.4CHGA, SYP
31esophagus adenocarcinoma10.4CHGA, SYP
32fraxf syndrome10.4CHGA, SYP
33froelich syndrome10.4CHGA, SYP
34mixed endometrial stromal and smooth muscle tumor10.4CHGA, SYP
35lumbar plexus neoplasm10.4CHGA, SYP
36cutaneous mastocytosis10.4CHGA, SYP
37pancreatic serous cystic neoplasm10.4CHGA, SYP
38pilocytic astrocytoma10.4CHGA, SYP
39subpulmonary stenosis10.4CHGA, SYP
40urethral villous adenoma10.4CHGA, SERPINA1
41orbit rhabdomyosarcoma10.4AFP, SYP
42parathyroid gland disease10.4AFP, SST
43diencephalic astrocytomas10.4CHGA, SYP
44brain stem ependymoma10.4CHGA, SYP
45pneumonia10.4CHGA, SYP
46verruciform xanthoma of skin10.4CHGA, SYP
47ovarian clear cell malignant adenofibroma10.4CHGA, SYP
48rectum signet ring adenocarcinoma10.4CHGA, SYP
49classic pulmonary blastoma10.4CHGA, SYP
50retinal melanoma10.4SST, SYP

Graphical network of the top 20 diseases related to Pancreatoblastoma:



Diseases related to pancreatoblastoma

Symptoms for Pancreatoblastoma

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Human phenotypes related to Pancreatoblastoma:

 53 (show all 6)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 weight loss53 Frequent (79-30%)
2 vomiting53 Frequent (79-30%)
3 diarrhea53 Frequent (79-30%)
4 abdominal pain53 Frequent (79-30%)
5 elevated maternal serum alpha-fetoprotein53 Frequent (79-30%)
6 jaundice53 Occasional (29-5%)

UMLS symptoms related to Pancreatoblastoma:


abdominal pain, pruritus

Drugs & Therapeutics for Pancreatoblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Pancreatoblastoma


Cochrane evidence based reviews: pancreatoblastoma

Genetic Tests for Pancreatoblastoma

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Anatomical Context for Pancreatoblastoma

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MalaCards organs/tissues related to Pancreatoblastoma:

35
Pancreas, Liver, Brain

Animal Models for Pancreatoblastoma or affiliated genes

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Publications for Pancreatoblastoma

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Articles related to Pancreatoblastoma:

(show top 50)    (show all 125)
idTitleAuthorsYear
1
Pancreatoblastoma an Unusual Occurrence of a Tumour in Paediatric Age Group: A Case Report. (27134883)
2016
2
Adult pancreatoblastoma - Case report and review of literature. (27761191)
2016
3
Clinicopathological review of pancreatoblastoma in adults. (26312218)
2015
4
Ectopic Cushing syndrome secondary to recurrent pancreatoblastoma in a child: Lessons learnt. (26881602)
2015
5
CT-guided radiofrequency ablation following high-dose chemotherapy of a liver-metastasizing pancreatoblastoma with tumor thrombus in the portal vein. (23828484)
2013
6
Autologous stem cell transplantation as first line treatment after incomplete excision of pancreatoblastoma. (23741195)
2013
7
Congenital pancreatoblastoma: report of an atypical case and review of the literature. (22278199)
2012
8
Management of pancreatoblastoma in children and young adults. (22525406)
2012
9
Pancreatoblastoma: a rare tumor still evolving in clinical presentation and histology. (22572137)
2012
10
Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT). (21696948)
2011
11
Pancreatoblastoma in an adult patient. A case report. (19287117)
2009
12
Fluorescence in situ hybridization analysis of pancreatoblastoma. (19238024)
2009
13
Revisiting metastatic adult pancreatoblastoma. A case and review of the literature. (18981556)
2008
14
Long-term survival of pancreatoblastoma in children. (18090935)
2007
15
Adrenocorticotropin-secreting pancreatoblastoma. (17642425)
2007
16
Pancreatoblastoma metastases to the brain. Case illustration. (17330549)
2007
17
Aggressive surgical and chemotherapeutic treatment of advanced pancreatoblastoma associated with tumor thrombus in portal vein. (16516645)
2006
18
Pancreatoblastoma in a teenage patient. (16728924)
2006
19
Pancreatoblastoma in an adult woman: sonography, CT, and dynamic gadolinium-enhanced MRI features. (15728031)
2005
20
Expression pattern of keratin subclasses in pancreatoblastoma with special emphasis on squamoid corpuscles. (15943785)
2005
21
Diagnosis, treatment and outcome of pancreatoblastoma. (15256806)
2004
22
Septal enhancement within pancreatoblastoma of the pancreatic head presenting with progressive anaemia. (15205844)
2004
23
Significance of aberrant (cytoplasmic/nuclear) expression of beta-catenin in pancreatoblastoma. (12533831)
2003
24
Pancreatoblastoma. A case report with special emphasis on squamoid corpuscles with optically clear nuclei rich in biotin. (12920766)
2003
25
Pancreatoblastoma is associated with chromosome 11p loss of heterozygosity and IGF2 overexpression. (12116082)
2002
26
Beckwith-Wiedemann syndrome, pancreatoblastoma, and the wnt signaling pathway. (11943738)
2002
27
Pancreatoblastoma. (11770246)
2001
28
Imaging features of pancreatoblastoma. (11486805)
2001
29
Prolonged survival after resection of pancreatoblastoma and synchronous liver metastases in an adult. (11677959)
2001
30
Pancreatoblastoma treated by delayed operation after effective chemotherapy. (11083448)
2000
31
Pancreatoblastoma: a second report on cytogenetic findings. (10087957)
1999
32
Pancreatoblastoma in an adolescent girl: case report and review of 26 Japanese cases. (9641374)
1998
33
Pancreatoblastoma in childhood: the role of alpha-fetoprotein". (9403024)
1998
34
Pancreatoblastoma. (9396538)
1997
35
Pancreatoblastoma: a histochemical and immunohistochemical analysis. (8944621)
1996
36
Adult pancreatoblastoma: a case report and review of the literature. (8792711)
1996
37
Adenocarcinoma of the pancreas in childhood (pancreatoblastoma): report of a case with good response to chemotherapy. (8804461)
1995
38
Pancreatoblastoma. (8617563)
1995
39
Pancreatoblastoma: a case report. (7954063)
1994
40
Pancreatoblastoma and solid and cystic papillary tumor: two tumors related to pancreatic ontogeny. (7809509)
1994
41
Pancreatoblastoma--histopathological and ultrastructural analysis of two cases. (1524733)
1992
42
Pancreatoblastoma: response to chemotherapy. (1708850)
1991
43
Pancreatoblastoma with marked elevation of serum alpha-fetoprotein. An autopsy case report with immunocytochemical study. (1689089)
1990
44
Use of enzyme histochemistry in the diagnosis of pancreatoblastoma. (2553578)
1989
45
Recurrent pancreatoblastoma with inappropriate adrenocorticotrophic hormone secretion. (2852926)
1988
46
Immunohistochemical study of pancreatoblastoma. (2449037)
1987
47
Pancreatoblastoma in Japan, with differential diagnosis from papillary cystic tumor (ductuloacinar adenoma) of the pancreas. (3554891)
1987
48
Radiotherapy for locally recurrent infantile pancreatic carcinoma (pancreatoblastoma). (3115557)
1987
49
Pancreatoblastoma in an adult. (3013120)
1986
50
Alpha-fetoprotein-producing pancreatoblastoma. A case report. (2420440)
1986

Variations for Pancreatoblastoma

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Expression for genes affiliated with Pancreatoblastoma

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Search GEO for disease gene expression data for Pancreatoblastoma.

Pathways for genes affiliated with Pancreatoblastoma

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Pathways related to Pancreatoblastoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
18.8AFP, KRT14, KRT17

GO Terms for genes affiliated with Pancreatoblastoma

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Cellular components related to Pancreatoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell peripheryGO:00719449.1KRT14, KRT17

Biological processes related to Pancreatoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hyperosmotic responseGO:00069729.3NTS, SST

Sources for Pancreatoblastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet