MCID: PNC019
MIFTS: 33

Pancreatoblastoma

Categories: Rare diseases, Endocrine diseases, Gastrointestinal diseases, Cancer diseases

Aliases & Classifications for Pancreatoblastoma

MalaCards integrated aliases for Pancreatoblastoma:

Name: Pancreatoblastoma 12 72 49 55 41 14 69

Characteristics:

Orphanet epidemiological data:

55
pancreatoblastoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe),<1/1000000 (Worldwide); Age of onset: Adult,Childhood; Age of death: adult,early childhood,late childhood;

Classifications:



External Ids:

Disease Ontology 12 DOID:6823
MeSH 41 C537162
NCIt 46 C4265
SNOMED-CT 64 189814006 53618008
Orphanet 55 ORPHA677
MESH via Orphanet 42 C537162
UMLS via Orphanet 70 C0334489
ICD10 via Orphanet 33 C25.1
UMLS 69 C0334489

Summaries for Pancreatoblastoma

MalaCards based summary : Pancreatoblastoma is related to acinar cell carcinoma and ectopic cushing syndrome, and has symptoms including weight loss, vomiting and diarrhea. An important gene associated with Pancreatoblastoma is AFP (Alpha Fetoprotein). Affiliated tissues include pancreas, lymph node and liver.

Wikipedia : 72 Pancreatoblastoma is a rare type of pancreatic... more...

Related Diseases for Pancreatoblastoma

Diseases related to Pancreatoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
# Related Disease Score Top Affiliating Genes
1 acinar cell carcinoma 30.2 AFP CHGA SERPINA1
2 ectopic cushing syndrome 29.9 SST SYP
3 adenoma of the pancreas 29.6 CHGA SST SYP
4 mucinous cystadenofibroma 10.4 AFP SERPINA1
5 polyembryoma 10.4 AFP SERPINA1
6 malignant sertoli cell tumor 10.4 AFP SYP
7 malignant teratoma 10.4 AFP SYP
8 adult teratoma 10.4 AFP CHGA
9 endometrial small cell carcinoma 10.4 AFP SYP
10 ovarian endodermal sinus tumor 10.4 AFP SERPINA1
11 mediastinal cancer 10.4 AFP SYP
12 sclerosing hepatic carcinoma 10.4 AFP CHGA
13 seminal vesicle tumor 10.4 AFP SYP
14 pancreatic acinar cell adenocarcinoma 10.4 AFP CHGA
15 ovarian primitive germ cell tumor 10.4 AFP SERPINA1
16 cystadenofibroma 10.4 AFP SERPINA1
17 pineoblastoma 10.4 AFP SYP
18 liver sarcoma 10.3 AFP CHGA
19 ureter small cell carcinoma 10.3 CHGA SYP
20 esophageal neuroendocrine tumor 10.3 CHGA SYP
21 urinary bladder small cell neuroendocrine carcinoma 10.3 CHGA SYP
22 ovarian large-cell neuroendocrine carcinoma 10.3 CHGA SYP
23 auditory system cancer 10.3 CHGA SYP
24 peritoneal serous adenocarcinoma 10.3 CHGA SYP
25 cellular ependymoma 10.3 CHGA SYP
26 gallbladder small cell carcinoma 10.3 CHGA SYP
27 primary hepatic neuroendocrine carcinoma 10.3 CHGA SYP
28 small cell carcinoma of the bladder 10.3 CHGA SYP
29 gastrointestinal neuroendocrine tumor 10.3 CHGA SYP
30 pulmonary large cell neuroendocrine carcinoma 10.3 CHGA SYP
31 atypical follicular adenoma 10.3 CHGA SYP
32 chordoid meningioma 10.3 CHGA SYP
33 olfactory nerve neoplasm 10.3 CHGA SYP
34 pancreatic serous cystadenoma 10.3 CHGA SYP
35 cauda equina neoplasm 10.3 CHGA SYP
36 conventional angiosarcoma 10.3 CHGA SYP
37 subependymoma 10.3 CHGA SYP
38 pulmonary sclerosing hemangioma 10.3 CHGA SYP
39 pineocytoma 10.3 CHGA SYP
40 gastric squamous cell carcinoma 10.3 CHGA SYP
41 gastric small cell carcinoma 10.3 CHGA SYP
42 small cell neuroendocrine carcinoma 10.3 CHGA SYP
43 pulmonary blastoma 10.3 CHGA SYP
44 pleomorphic xanthoastrocytoma 10.3 CHGA SYP
45 ureter, cancer of 10.3 CHGA SYP
46 botryoid rhabdomyosarcoma 10.3 AFP SYP
47 esophageal varix 10.3 AFP SST
48 malignant glandular tumor of peripheral nerve sheath 10.3 SST SYP
49 pancreatic somatostatinoma 10.3 SST SYP
50 tanycytic ependymoma 10.3 CHGA SYP

Graphical network of the top 20 diseases related to Pancreatoblastoma:



Diseases related to Pancreatoblastoma

Symptoms & Phenotypes for Pancreatoblastoma

Human phenotypes related to Pancreatoblastoma:

55 31 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 weight loss 55 31 frequent (33%) Frequent (79-30%) HP:0001824
2 vomiting 55 31 frequent (33%) Frequent (79-30%) HP:0002013
3 diarrhea 55 31 frequent (33%) Frequent (79-30%) HP:0002014
4 abdominal pain 55 31 frequent (33%) Frequent (79-30%) HP:0002027
5 abdominal distention 55 31 frequent (33%) Frequent (79-30%) HP:0003270
6 pancreatic calcification 55 31 frequent (33%) Frequent (79-30%) HP:0005213
7 elevated maternal serum alpha-fetoprotein 55 31 frequent (33%) Frequent (79-30%) HP:0005984
8 jaundice 55 31 occasional (7.5%) Occasional (29-5%) HP:0000952
9 abnormality of the lymph nodes 55 31 occasional (7.5%) Occasional (29-5%) HP:0002733

UMLS symptoms related to Pancreatoblastoma:


pruritus, icterus, abdominal pain

Drugs & Therapeutics for Pancreatoblastoma

Search Clinical Trials , NIH Clinical Center for Pancreatoblastoma

Cochrane evidence based reviews: pancreatoblastoma

Genetic Tests for Pancreatoblastoma

Anatomical Context for Pancreatoblastoma

MalaCards organs/tissues related to Pancreatoblastoma:

38
Pancreas, Lymph Node, Liver, Brain

Publications for Pancreatoblastoma

Articles related to Pancreatoblastoma:

(show top 50) (show all 131)
# Title Authors Year
1
Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma. ( 29233928 )
2018
2
Liver transplant for metastatic pancreatoblastoma: 7-year event-free survival after chemotherapy, pancreatectomy, complete hepatectomy, and liver transplant. ( 29235221 )
2018
3
Pancreatoblastoma Masquerading as a Retroperitoneal Germ Cell Tumor. ( 28082787 )
2017
4
Complete Resection of Pancreatoblastoma With Portal Vein Obstruction After High-dose Chemotherapy: A Case Report. ( 28538503 )
2017
5
Pancreatoblastoma: an unusual diagnosis in an adult patient. ( 29285688 )
2017
6
Pancreatoblastoma With Metastatic Retroperitoneal Lymph Node and PET/CT. ( 28872552 )
2017
7
Pancreatoblastoma: an Atypical Presentation and a Literature Review. ( 28194556 )
2017
8
Multi-Visceral Transplantation in a 21-Year-Old Man with Prior Pancreatoblastoma. ( 27721967 )
2016
9
Adult pancreatoblastoma - Case report and review of literature. ( 27761191 )
2016
10
Pancreatoblastoma masquerading as hepatoblastoma: A diagnostic dilemma. ( 27046982 )
2016
11
Fine needle aspiration cytology diagnosis of a pancreatoblastoma in an infant: case report with a summary of prior published cases. ( 27038102 )
2016
12
Pancreatoblastoma an Unusual Occurrence of a Tumour in Paediatric Age Group: A Case Report. ( 27134883 )
2016
13
Multifocal pancreatoblastoma with pseudocyst in a 2-year-old boy. ( 26591960 )
2015
14
Adult pancreatoblastoma: A case report and review of the literature. ( 26137059 )
2015
15
Clinicopathological review of pancreatoblastoma in adults. ( 26312218 )
2015
16
Response of Relapsed Pancreatoblastoma to a Combination of Vinorelbine and Oral Cyclophosphamide. ( 26056794 )
2015
17
Pancreatoblastoma in an adult. ( 25673604 )
2015
18
Ectopic Cushing syndrome secondary to recurrent pancreatoblastoma in a child: Lessons learnt. ( 26881602 )
2015
19
Pancreatoblastoma, a Rare Childhood Tumor: A Case Report. ( 25110242 )
2014
20
CT-guided radiofrequency ablation following high-dose chemotherapy of a liver-metastasizing pancreatoblastoma with tumor thrombus in the portal vein. ( 23828484 )
2013
21
Use of gemcitabine with multi-stage surgical resection as successful second-line treatment of metastatic pancreatoblastoma. ( 23042010 )
2013
22
Spontaneous rupture of an advanced pancreatoblastoma: aberrant RASSF1A methylation and CTNNB1 mutation as molecular genetic markers. ( 23583162 )
2013
23
Pancreatoblastoma: a rare, adult pancreatic tumor with many faces. ( 23991735 )
2013
24
Infantile Extrapancreatic Pancreatoblastoma: A Report on a Rare Infantile Abdominal Mass. ( 24072247 )
2013
25
Autologous stem cell transplantation as first line treatment after incomplete excision of pancreatoblastoma. ( 23741195 )
2013
26
The diagnosis and surgical treatment of pancreatoblastoma in adults: a case series and review of the literature. ( 24081396 )
2013
27
Congenital pancreatoblastoma: report of an atypical case and review of the literature. ( 22278199 )
2012
28
Pancreatoblastoma: a rare tumor still evolving in clinical presentation and histology. ( 22572137 )
2012
29
Management of pancreatoblastoma in children and young adults. ( 22525406 )
2012
30
Clinical analysis of childhood pancreatoblastoma arising from the tail of the pancreas. ( 22584784 )
2012
31
Congenital pancreatoblastoma associated with I^-catenin mutation. ( 21953767 )
2012
32
Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT). ( 21696948 )
2011
33
Central pancreatectomy for pancreatoblastoma in a 16-year-old girl. ( 21843703 )
2011
34
Synchronous ectopic pancreatoblastoma in a child: a case report. ( 21655073 )
2011
35
Imaging findings of pancreatoblastoma in 4 children including a case of ectopic pancreatoblastoma. ( 20686762 )
2010
36
Pancreatoblastoma: two case reports from a medical center in Taiwan. ( 20057322 )
2010
37
Corticotropin-releasing hormone-secreting pancreatoblastoma in an adult patient. ( 20664482 )
2010
38
Pancreaticoduodenectomy for pancreatoblastoma: a case report and literature review. ( 20165952 )
2010
39
Simultaneous occurrence of pancreatoblastoma and neuroblastoma in a newborn with beckwith-wiedemann syndrome. ( 20495482 )
2010
40
Successful treatment of advanced pancreatoblastoma by a pylorus-preserving pancreatoduodenectomy after radiation and high-dose chemotherapy. ( 20632017 )
2010
41
Autologous stem cell transplantation as treatment modality in a patient with relapsed pancreatoblastoma. ( 20658635 )
2010
42
Fluorescence in situ hybridization analysis of pancreatoblastoma. ( 19238024 )
2009
43
Imprint cytology of pancreatoblastoma: a case report and review of the literature. ( 19229998 )
2009
44
Expression pattern of claudins 5 and 7 distinguishes solid-pseudopapillary from pancreatoblastoma, acinar cell and endocrine tumors of the pancreas. ( 19194274 )
2009
45
Pancreatoblastoma in adults: a review of the literature. ( 19077457 )
2009
46
Pancreatoblastoma in an adult patient. A case report. ( 19287117 )
2009
47
Childhood pancreatoblastoma: clinical features and immunohistochemistry analysis. ( 18308466 )
2008
48
Revisiting metastatic adult pancreatoblastoma. A case and review of the literature. ( 18981556 )
2008
49
A peculiar variant of pancreatoblastoma in an adult. ( 18362850 )
2008
50
Pancreatoblastoma metastases to the brain. Case illustration. ( 17330549 )
2007

Variations for Pancreatoblastoma

Expression for Pancreatoblastoma

Search GEO for disease gene expression data for Pancreatoblastoma.

Pathways for Pancreatoblastoma

GO Terms for Pancreatoblastoma

Sources for Pancreatoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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