MCID: PNC019
MIFTS: 32

Pancreatoblastoma malady

Categories: Rare diseases, Gastrointestinal diseases, Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatoblastoma

Aliases & Descriptions for Pancreatoblastoma:

Name: Pancreatoblastoma 12 50 56 42 14 69

Characteristics:

Orphanet epidemiological data:

56
pancreatoblastoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe),<1/1000000 (Worldwide); Age of onset: Adult,Childhood; Age of death: adult,early childhood,late childhood;

Classifications:



External Ids:

Disease Ontology 12 DOID:6823
MeSH 42 C537162
NCIt 47 C4265
SNOMED-CT 64 189814006 53618008
Orphanet 56 ORPHA677
MESH via Orphanet 43 C537162
UMLS via Orphanet 70 C0334489
ICD10 via Orphanet 34 C25.1
UMLS 69 C0334489

Summaries for Pancreatoblastoma

MalaCards based summary : Pancreatoblastoma is related to rete testis adenoma and pontine hemorrhage, and has symptoms including abdominal pain, vomiting and diarrhea. An important gene associated with Pancreatoblastoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is Glucocorticoid receptor regulatory network. Affiliated tissues include pancreas, liver and brain, and related phenotype is Increased shRNA abundance.

Wikipedia : 71 Pancreatoblastoma is a rare type of pancreatic... more...

Related Diseases for Pancreatoblastoma

Diseases related to Pancreatoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
id Related Disease Score Top Affiliating Genes
1 rete testis adenoma 10.3 AFP SERPINA1
2 pontine hemorrhage 10.3 AFP SERPINA1
3 infiltrating renal pelvis transitional cell carcinoma 10.3 AFP SYP
4 proliferative glomerulonephritis 10.3 AFP SYP
5 ovarian germ cell teratoma 10.3 AFP SYP
6 vipoma 10.3 AFP CHGA
7 kidney disease 10.3 AFP SYP
8 rectum leiomyoma 10.3 AFP SYP
9 malignant granular cell myoblastoma 10.3 AFP CHGA
10 nipple neoplasm 10.3 AFP SYP
11 uterine corpus serous adenocarcinoma 10.2 AFP CHGA
12 medullomyoblastoma 10.2 AFP SYP
13 pneumothorax 10.2 AFP SYP
14 retroperitoneal hemangiopericytoma 10.2 AFP SERPINA1
15 pigmented villonodular synovitis 10.2 AFP CHGA
16 peroneal nerve paralysis 10.2 CHGA SYP
17 thymus small cell carcinoma 10.2 CHGA SYP
18 brain stem ependymoma 10.2 CHGA SYP
19 non specific chronic endometritis 10.2 CHGA SYP
20 cellular ependymoma 10.2 AFP SERPINA1
21 prolactin producing pituitary tumor 10.2 CHGA SYP
22 epithelioid malignant peripheral nerve sheath tumor 10.2 CHGA SYP
23 cartilage cancer 10.2 CHGA SYP
24 arthus reaction 10.2 AFP SYP
25 villous adenocarcinoma 10.2 CHGA SYP
26 jejunal neuroendocrine tumor 10.2 CHGA SYP
27 renal pelvis adenocarcinoma 10.2 CHGA SYP
28 spasmodic dysphonia 10.2 CHGA SYP
29 barre-lieou syndrome 10.2 CHGA SYP
30 microinvasive cervical squamous cell carcinoma 10.2 CHGA SYP
31 perineural angioma 10.2 CHGA SYP
32 gastric duplication cysts 10.2 CHGA SYP
33 diffuse cutaneous mastocytosis 10.2 CHGA SYP
34 hair follicle neoplasm 10.2 AFP SERPINA1
35 main bronchus cancer 10.2 CHGA SYP
36 gliofibroma 10.2 CHGA SYP
37 cavernous hemangioma of face 10.2 CHGA SYP
38 superior vena cava syndrome 10.2 CHGA SYP
39 exudative glomerulonephritis 10.2 CHGA SYP
40 fragile x-associated tremor/ataxia syndrome 10.2 CHGA SYP
41 hepatorenal syndrome 10.2 CHGA SYP
42 acalculous cholecystitis 10.2 CHGA SYP
43 postgastrectomy syndrome 10.2 SST SYP
44 piussan lenaerts mathieu syndrome 10.2 CHGA SYP
45 brain stem astrocytic neoplasm 10.2 CHGA SYP
46 anal squamous cell carcinoma 10.2 CHGA SYP
47 sclerosing hemangioma 10.2 AFP CHGA
48 pemphigus foliaceus 10.2 SST SYP
49 uterine corpus myxoid leiomyosarcoma 10.2 CHGA SYP
50 calcific tendinitis 10.2 CHGA SYP

Graphical network of the top 20 diseases related to Pancreatoblastoma:



Diseases related to Pancreatoblastoma

Symptoms & Phenotypes for Pancreatoblastoma

Human phenotypes related to Pancreatoblastoma:

56 32 (show all 6)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abdominal pain 56 32 Frequent (79-30%) HP:0002027
2 vomiting 56 32 Frequent (79-30%) HP:0002013
3 diarrhea 56 32 Frequent (79-30%) HP:0002014
4 weight loss 56 32 Frequent (79-30%) HP:0001824
5 jaundice 56 32 Occasional (29-5%) HP:0000952
6 elevated maternal serum alpha-fetoprotein 56 32 Frequent (79-30%) HP:0005984

UMLS symptoms related to Pancreatoblastoma:


abdominal pain, icterus, pruritus

GenomeRNAi Phenotypes related to Pancreatoblastoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 8.8 AFP KRT14 KRT17

Drugs & Therapeutics for Pancreatoblastoma

Search Clinical Trials , NIH Clinical Center for Pancreatoblastoma

Cochrane evidence based reviews: pancreatoblastoma

Genetic Tests for Pancreatoblastoma

Anatomical Context for Pancreatoblastoma

MalaCards organs/tissues related to Pancreatoblastoma:

39
Pancreas, Liver, Brain

Publications for Pancreatoblastoma

Articles related to Pancreatoblastoma:

(show top 50) (show all 125)
id Title Authors Year
1
Pancreatoblastoma Masquerading as a Retroperitoneal Germ Cell Tumor. ( 28082787 )
2017
2
Fine needle aspiration cytology diagnosis of a pancreatoblastoma in an infant: case report with a summary of prior published cases. ( 27038102 )
2016
3
Multi-Visceral Transplantation in a 21-Year-Old Man with Prior Pancreatoblastoma. ( 27721967 )
2016
4
Adult pancreatoblastoma - Case report and review of literature. ( 27761191 )
2016
5
Pancreatoblastoma an Unusual Occurrence of a Tumour in Paediatric Age Group: A Case Report. ( 27134883 )
2016
6
Pancreatoblastoma masquerading as hepatoblastoma: A diagnostic dilemma. ( 27046982 )
2016
7
Response of Relapsed Pancreatoblastoma to a Combination of Vinorelbine and Oral Cyclophosphamide. ( 26056794 )
2015
8
Ectopic Cushing syndrome secondary to recurrent pancreatoblastoma in a child: Lessons learnt. ( 26881602 )
2015
9
Adult pancreatoblastoma: A case report and review of the literature. ( 26137059 )
2015
10
Pancreatoblastoma in an adult. ( 25673604 )
2015
11
Clinicopathological review of pancreatoblastoma in adults. ( 26312218 )
2015
12
Multifocal pancreatoblastoma with pseudocyst in a 2-year-old boy. ( 26591960 )
2015
13
Pancreatoblastoma, a Rare Childhood Tumor: A Case Report. ( 25110242 )
2014
14
Pancreatoblastoma: a rare, adult pancreatic tumor with many faces. ( 23991735 )
2013
15
Infantile Extrapancreatic Pancreatoblastoma: A Report on a Rare Infantile Abdominal Mass. ( 24072247 )
2013
16
Use of gemcitabine with multi-stage surgical resection as successful second-line treatment of metastatic pancreatoblastoma. ( 23042010 )
2013
17
Autologous stem cell transplantation as first line treatment after incomplete excision of pancreatoblastoma. ( 23741195 )
2013
18
CT-guided radiofrequency ablation following high-dose chemotherapy of a liver-metastasizing pancreatoblastoma with tumor thrombus in the portal vein. ( 23828484 )
2013
19
The diagnosis and surgical treatment of pancreatoblastoma in adults: a case series and review of the literature. ( 24081396 )
2013
20
Spontaneous rupture of an advanced pancreatoblastoma: aberrant RASSF1A methylation and CTNNB1 mutation as molecular genetic markers. ( 23583162 )
2013
21
Congenital pancreatoblastoma: report of an atypical case and review of the literature. ( 22278199 )
2012
22
Clinical analysis of childhood pancreatoblastoma arising from the tail of the pancreas. ( 22584784 )
2012
23
Management of pancreatoblastoma in children and young adults. ( 22525406 )
2012
24
Pancreatoblastoma: a rare tumor still evolving in clinical presentation and histology. ( 22572137 )
2012
25
Congenital pancreatoblastoma associated with I^-catenin mutation. ( 21953767 )
2012
26
Central pancreatectomy for pancreatoblastoma in a 16-year-old girl. ( 21843703 )
2011
27
Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT). ( 21696948 )
2011
28
Synchronous ectopic pancreatoblastoma in a child: a case report. ( 21655073 )
2011
29
Corticotropin-releasing hormone-secreting pancreatoblastoma in an adult patient. ( 20664482 )
2010
30
Autologous stem cell transplantation as treatment modality in a patient with relapsed pancreatoblastoma. ( 20658635 )
2010
31
Simultaneous occurrence of pancreatoblastoma and neuroblastoma in a newborn with beckwith-wiedemann syndrome. ( 20495482 )
2010
32
Imaging findings of pancreatoblastoma in 4 children including a case of ectopic pancreatoblastoma. ( 20686762 )
2010
33
Successful treatment of advanced pancreatoblastoma by a pylorus-preserving pancreatoduodenectomy after radiation and high-dose chemotherapy. ( 20632017 )
2010
34
Pancreaticoduodenectomy for pancreatoblastoma: a case report and literature review. ( 20165952 )
2010
35
Pancreatoblastoma: two case reports from a medical center in Taiwan. ( 20057322 )
2010
36
Pancreatoblastoma in an adult patient. A case report. ( 19287117 )
2009
37
Expression pattern of claudins 5 and 7 distinguishes solid-pseudopapillary from pancreatoblastoma, acinar cell and endocrine tumors of the pancreas. ( 19194274 )
2009
38
Pancreatoblastoma in adults: a review of the literature. ( 19077457 )
2009
39
Imprint cytology of pancreatoblastoma: a case report and review of the literature. ( 19229998 )
2009
40
Fluorescence in situ hybridization analysis of pancreatoblastoma. ( 19238024 )
2009
41
Childhood pancreatoblastoma: clinical features and immunohistochemistry analysis. ( 18308466 )
2008
42
A peculiar variant of pancreatoblastoma in an adult. ( 18362850 )
2008
43
Revisiting metastatic adult pancreatoblastoma. A case and review of the literature. ( 18981556 )
2008
44
Pancreatoblastoma. ( 17228135 )
2007
45
Diagnosis and treatment of pancreatoblastoma in China. ( 17198189 )
2007
46
Adrenocorticotropin-secreting pancreatoblastoma. ( 17642425 )
2007
47
Pancreatoblastoma metastases to the brain. Case illustration. ( 17330549 )
2007
48
Long-term survival of pancreatoblastoma in children. ( 18090935 )
2007
49
Pancreatoblastoma in a teenage patient. ( 16728924 )
2006
50
A case of pancreatoblastoma prenatally diagnosed as intraperitoneal cyst. ( 16896817 )
2006

Variations for Pancreatoblastoma

Expression for Pancreatoblastoma

Search GEO for disease gene expression data for Pancreatoblastoma.

Pathways for Pancreatoblastoma

Pathways related to Pancreatoblastoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.71 AFP KRT14 KRT17

GO Terms for Pancreatoblastoma

Cellular components related to Pancreatoblastoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 KRT14 KRT17

Sources for Pancreatoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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