MCID: PNC019
MIFTS: 31

Pancreatoblastoma malady

Categories: Rare diseases, Gastrointestinal diseases, Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatoblastoma

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Sources:
11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 37MeSH, 66UMLS, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Pancreatoblastoma:

Name: Pancreatoblastoma 11 46 13 52 37 66

Characteristics:

Orphanet epidemiological data:

52
pancreatoblastoma:
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe),<1/1000000 (Worldwide); Age of onset: Adult,Childhood; Age of death: adult,early childhood,late childhood

Classifications:



External Ids:

Disease Ontology11 DOID:6823
MeSH37 C537162
NCIt43 C4265
Orphanet52 ORPHA677
SNOMED-CT60 189814006, 53618008
ICD10 via Orphanet29 C25.1
MESH via Orphanet38 C537162
UMLS via Orphanet67 C0334489

Summaries for Pancreatoblastoma

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Wikipedia:69 Pancreatoblastoma is a rare type of pancreatic cancer. more...

MalaCards based summary: Pancreatoblastoma is related to paranasal sinus cancer and epithelial predominant pulmonary blastoma, and has symptoms including abdominal pain, pruritus and Array. An important gene associated with Pancreatoblastoma is AFP (Alpha Fetoprotein). Affiliated tissues include pancreas, liver and brain.

Related Diseases for Pancreatoblastoma

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Diseases related to Pancreatoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 168)
idRelated DiseaseScoreTop Affiliating Genes
1paranasal sinus cancer10.7AFP, SYP
2epithelial predominant pulmonary blastoma10.6AFP, SYP
3ovarian germ cell teratoma10.6AFP, CHGA
4gastric teratoma10.6AFP, SYP
5adult teratoma10.6AFP, SYP
6prostate small cell carcinoma10.6AFP, SYP
7adult pineal parenchymal tumor10.6AFP, CHGA
8spontaneous tension pneumothorax10.6AFP, SYP
9female reproductive endometrioid cancer10.6AFP, SYP
10testicular gonadoblastoma10.6AFP, SYP
11ovary serous adenocarcinoma10.6AFP, CHGA
12large cell medulloblastoma10.6AFP, SYP
13ovary mixed epithelial carcinoma10.6CHGA, SYP
14esophagus small cell carcinoma10.6CHGA, SYP
15lice infestation10.6CHGA, SYP
16microglandular adenosis of breast10.6CHGA, SYP
17punctate porokeratosis10.6CHGA, SYP
18osteoblastoma10.6CHGA, SYP
19urethra adenocarcinoma10.6CHGA, SYP
20esophagus adenocarcinoma10.6CHGA, SYP
21nodular tenosynovitis10.6AFP, CHGA
22fraxf syndrome10.6CHGA, SYP
23froelich syndrome10.6CHGA, SYP
24mixed endometrial stromal and smooth muscle tumor10.6CHGA, SYP
25cutaneous mastocytosis10.6CHGA, SYP
26pancreatic serous cystic neoplasm10.6CHGA, SYP
27vibratory urticaria10.6AFP, SYP
28pilocytic astrocytoma10.6CHGA, SYP
29subpulmonary stenosis10.6CHGA, SYP
30nephrogenic adenofibroma10.6AFP, SYP
31diencephalic astrocytomas10.5CHGA, SYP
32brain stem ependymoma10.5CHGA, SYP
33pneumonia10.5CHGA, SYP
34verruciform xanthoma of skin10.5CHGA, SYP
35ovarian clear cell malignant adenofibroma10.5CHGA, SYP
36rectum signet ring adenocarcinoma10.5CHGA, SYP
37classic pulmonary blastoma10.5CHGA, SYP
38clear cell ependymoma10.5CHGA, SYP
39orbit rhabdomyosarcoma10.5AFP, SYP
40pancreatic agenesis10.5CHGA, SYP
41childhood teratocarcinoma of the testis10.5AFP, SERPINA1
42lassueur-graham-little syndrome10.5AFP, SERPINA1
43cranial nerve iii tumor10.5CHGA, SYP
44hypoparathyroidism-intellectual disability-dysmorphism syndrome10.5CHGA, SYP
452q33.1 microdeletion syndrome10.5MUC1, SYP
46large intestine lipoma10.5CHGA, SYP
47schwannoma of ureter10.5CHGA, SYP
48anal colloid adenocarcinoma10.5CHGA, SYP
49hyperuricemia10.5AFP, SERPINA1
50tricuspid valve insufficiency10.5AFP, MUC1

Graphical network of the top 20 diseases related to Pancreatoblastoma:



Diseases related to pancreatoblastoma

Symptoms for Pancreatoblastoma

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Symptoms:

 52
  • weight loss
  • vomiting
  • diarrhea
  • abdominal pain
  • elevated maternal serum alpha-fetoprotein
  • jaundice

UMLS symptoms related to Pancreatoblastoma:


abdominal pain, pruritus

Drugs & Therapeutics for Pancreatoblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Pancreatoblastoma


Cochrane evidence based reviews: pancreatoblastoma

Genetic Tests for Pancreatoblastoma

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Anatomical Context for Pancreatoblastoma

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MalaCards organs/tissues related to Pancreatoblastoma:

34
Pancreas, Liver, Brain

Animal Models for Pancreatoblastoma or affiliated genes

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Publications for Pancreatoblastoma

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Articles related to Pancreatoblastoma:

(show top 50)    (show all 122)
idTitleAuthorsYear
1
Pancreatoblastoma an Unusual Occurrence of a Tumour in Paediatric Age Group: A Case Report. (27134883)
2016
2
Clinicopathological review of pancreatoblastoma in adults. (26312218)
2015
3
Ectopic Cushing syndrome secondary to recurrent pancreatoblastoma in a child: Lessons learnt. (26881602)
2015
4
CT-guided radiofrequency ablation following high-dose chemotherapy of a liver-metastasizing pancreatoblastoma with tumor thrombus in the portal vein. (23828484)
2013
5
Autologous stem cell transplantation as first line treatment after incomplete excision of pancreatoblastoma. (23741195)
2013
6
Congenital pancreatoblastoma: report of an atypical case and review of the literature. (22278199)
2012
7
Management of pancreatoblastoma in children and young adults. (22525406)
2012
8
Pancreatoblastoma: a rare tumor still evolving in clinical presentation and histology. (22572137)
2012
9
Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT). (21696948)
2011
10
Pancreatoblastoma in an adult patient. A case report. (19287117)
2009
11
Fluorescence in situ hybridization analysis of pancreatoblastoma. (19238024)
2009
12
Revisiting metastatic adult pancreatoblastoma. A case and review of the literature. (18981556)
2008
13
Long-term survival of pancreatoblastoma in children. (18090935)
2007
14
Adrenocorticotropin-secreting pancreatoblastoma. (17642425)
2007
15
Pancreatoblastoma metastases to the brain. Case illustration. (17330549)
2007
16
Aggressive surgical and chemotherapeutic treatment of advanced pancreatoblastoma associated with tumor thrombus in portal vein. (16516645)
2006
17
Pancreatoblastoma in a teenage patient. (16728924)
2006
18
Pancreatoblastoma in an adult woman: sonography, CT, and dynamic gadolinium-enhanced MRI features. (15728031)
2005
19
Expression pattern of keratin subclasses in pancreatoblastoma with special emphasis on squamoid corpuscles. (15943785)
2005
20
Diagnosis, treatment and outcome of pancreatoblastoma. (15256806)
2004
21
Septal enhancement within pancreatoblastoma of the pancreatic head presenting with progressive anaemia. (15205844)
2004
22
Significance of aberrant (cytoplasmic/nuclear) expression of beta-catenin in pancreatoblastoma. (12533831)
2003
23
Pancreatoblastoma. A case report with special emphasis on squamoid corpuscles with optically clear nuclei rich in biotin. (12920766)
2003
24
Pancreatoblastoma is associated with chromosome 11p loss of heterozygosity and IGF2 overexpression. (12116082)
2002
25
Beckwith-Wiedemann syndrome, pancreatoblastoma, and the wnt signaling pathway. (11943738)
2002
26
Pancreatoblastoma. (11770246)
2001
27
Imaging features of pancreatoblastoma. (11486805)
2001
28
Prolonged survival after resection of pancreatoblastoma and synchronous liver metastases in an adult. (11677959)
2001
29
Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p. (11696422)
2001
30
Pancreatoblastoma treated by delayed operation after effective chemotherapy. (11083448)
2000
31
Pancreatoblastoma: a second report on cytogenetic findings. (10087957)
1999
32
Pancreatoblastoma in an adolescent girl: case report and review of 26 Japanese cases. (9641374)
1998
33
&quot;Pancreatoblastoma in childhood: the role of alpha-fetoprotein&quot;. (9403024)
1998
34
Pancreatoblastoma. (9396538)
1997
35
Pancreatoblastoma: a histochemical and immunohistochemical analysis. (8944621)
1996
36
Adult pancreatoblastoma: a case report and review of the literature. (8792711)
1996
37
Adenocarcinoma of the pancreas in childhood (pancreatoblastoma): report of a case with good response to chemotherapy. (8804461)
1995
38
Pancreatoblastoma. (8617563)
1995
39
Pancreatoblastoma: a case report. (7954063)
1994
40
Pancreatoblastoma and solid and cystic papillary tumor: two tumors related to pancreatic ontogeny. (7809509)
1994
41
Pancreatoblastoma--histopathological and ultrastructural analysis of two cases. (1524733)
1992
42
Pancreatoblastoma: response to chemotherapy. (1708850)
1991
43
Pancreatoblastoma with marked elevation of serum alpha-fetoprotein. An autopsy case report with immunocytochemical study. (1689089)
1990
44
Use of enzyme histochemistry in the diagnosis of pancreatoblastoma. (2553578)
1989
45
Recurrent pancreatoblastoma with inappropriate adrenocorticotrophic hormone secretion. (2852926)
1988
46
Immunohistochemical study of pancreatoblastoma. (2449037)
1987
47
Pancreatoblastoma in Japan, with differential diagnosis from papillary cystic tumor (ductuloacinar adenoma) of the pancreas. (3554891)
1987
48
Radiotherapy for locally recurrent infantile pancreatic carcinoma (pancreatoblastoma). (3115557)
1987
49
Pancreatoblastoma in an adult. (3013120)
1986
50
Alpha-fetoprotein-producing pancreatoblastoma. A case report. (2420440)
1986

Variations for Pancreatoblastoma

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Expression for genes affiliated with Pancreatoblastoma

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Search GEO for disease gene expression data for Pancreatoblastoma.

Pathways for genes affiliated with Pancreatoblastoma

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GO Terms for genes affiliated with Pancreatoblastoma

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Cellular components related to Pancreatoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.2AFP, CHGA, MUC1, SERPINA1, SST

Biological processes related to Pancreatoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hyperosmotic responseGO:00069729.3NTS, SST

Sources for Pancreatoblastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet