Aliases & Classifications for Pancytopenia

MalaCards integrated aliases for Pancytopenia:

Name: Pancytopenia 12 28 51 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:12450
ICD10 32 D61.81
ICD9CM 34 284.1
MeSH 41 D010198
UMLS 69 C0030312

Summaries for Pancytopenia

MalaCards based summary : Pancytopenia is related to amegakaryocytic thrombocytopenia, congenital and dyskeratosis congenita. An important gene associated with Pancytopenia is SAMD9L (Sterile Alpha Motif Domain Containing 9 Like), and among its related pathways/superpathways are Jak-STAT signaling pathway (KEGG) and Lung fibrosis. The drugs Benzocaine and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and t cells, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 72 Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood... more...

Related Diseases for Pancytopenia

Diseases related to Pancytopenia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 329)
# Related Disease Score Top Affiliating Genes
1 amegakaryocytic thrombocytopenia, congenital 31.7 MPL THPO
2 dyskeratosis congenita 31.3 CSF2 CSF3 DKC1 EPO LIG4 TERT
3 splenomegaly 30.2 EPO MPL
4 neutropenia 29.6 CSF2 CSF3 TPMT
5 myeloma, multiple 29.3 CSF2 CSF3 LIG4
6 refractory anemia 29.2 EPO MPL
7 malaria 29.0 CSF2 CSF3 DHFR EPO TCN2
8 deficiency anemia 29.0 CSF3 EPO THPO
9 hypersplenism 29.0 EPO THPO
10 thrombocytopenia 28.9 CSF3 MPL THPO
11 aplastic anemia 28.9 CSF1 CSF2 CSF3 DKC1 EPO MPL
12 myelofibrosis 28.9 CSF3 EPO MPL THPO
13 polycythemia 28.5 EPO MPL THPO
14 polycythemia vera 28.5 EPO MPL THPO
15 thrombocytosis 28.1 CSF2 EPO MPL THPO
16 myelodysplastic syndrome 27.9 CSF1 CSF2 CSF3 EPO MPL TERT
17 leukemia, chronic myeloid 27.7 CSF2 CSF3 EPO MPL THPO
18 leukemia, acute myeloid 27.3 CSF1 CSF2 CSF3 MPL SAMD9L TERT
19 ataxia-pancytopenia syndrome 12.4
20 samd9l-related ataxia-pancytopenia syndrome 12.0
21 pancytopenia and occlusive vascular disease 11.9
22 fanconi anemia, complementation group a 11.9
23 dyskeratosis congenita, x-linked 11.3
24 fanconi anemia, complementation group c 11.1
25 fanconi anemia, complementation group d2 11.1
26 fanconi anemia, complementation group b 11.1
27 hemophagocytic lymphohistiocytosis 11.1
28 fanconi-like syndrome 11.1
29 sackey sakati aur syndrome 11.0
30 radioulnar synostosis with amegakaryocytic thrombocytopenia 2 10.9
31 bone marrow failure syndrome 3 10.9
32 cerebroretinal microangiopathy with calcifications and cysts 2 10.9
33 bone marrow failure syndrome 2 10.8
34 immunodeficiency, common variable, 13 10.8
35 evans' syndrome 10.8
36 osteopetrosis, autosomal dominant 2 10.8
37 methylmalonyl-coa epimerase deficiency 10.8
38 osteopetrosis, autosomal recessive 1 10.8
39 osteopetrosis, autosomal recessive 2 10.8
40 osteopetrosis, autosomal recessive 5 10.8
41 osteopetrosis, autosomal recessive 3 10.8
42 transcobalamin ii deficiency 10.8
43 lymphoproliferative syndrome, x-linked, 2 10.8
44 lymphoproliferative syndrome, x-linked, 1 10.8
45 hemophagocytic lymphohistiocytosis, familial, 2 10.8
46 radioulnar synostosis with amegakaryocytic thrombocytopenia 1 10.8
47 transaldolase deficiency 10.8
48 lig4 syndrome 10.8
49 osteopetrosis, autosomal dominant 1 10.8
50 osteopetrosis, autosomal recessive 4 10.8

Graphical network of the top 20 diseases related to Pancytopenia:



Diseases related to Pancytopenia

Symptoms & Phenotypes for Pancytopenia

MGI Mouse Phenotypes related to Pancytopenia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.22 THPO TPMT TERT SH2D1A CSF1 EPO
2 homeostasis/metabolism MP:0005376 10.18 TERT THPO TPMT SH2D1A CSF1 EPO
3 immune system MP:0005387 10.1 THPO TERT SH2D1A CSF1 EPO CSF2
4 mortality/aging MP:0010768 9.93 TERT TPMT DNAJC21 CSF1 EPO CSF2
5 integument MP:0010771 9.8 DKC1 CSF1 EPO CSF2 CSF3 DHFR
6 neoplasm MP:0002006 9.43 TERT CSF2 LIG4 MGMT SAMD9L DKC1
7 respiratory system MP:0005388 9.1 TERT DKC1 CSF1 EPO CSF2 MGMT

Drugs & Therapeutics for Pancytopenia

Drugs for Pancytopenia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 173)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Phase 2 1994-09-7, 94-09-7 2337
2
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3 135968-09-1
3
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 1 53-03-2 5865
4
Oprelvekin Approved, Investigational Phase 4 145941-26-0
5
Etanercept Approved, Investigational Phase 4 185243-69-0
6 tannic acid Approved, Nutraceutical Phase 4,Phase 2
7 Cyclosporins Phase 4,Phase 3,Phase 2,Phase 1
8 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
9 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
10 Antilymphocyte Serum Phase 4,Phase 3,Phase 2,Phase 1
11 Analgesics Phase 4
12 Analgesics, Non-Narcotic Phase 4
13 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 1
14 Anti-Inflammatory Agents, Non-Steroidal Phase 4
15 Gastrointestinal Agents Phase 4,Phase 2,Phase 1
16 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
17
alemtuzumab Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 216503-57-0
18
Busulfan Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 55-98-1 2478
19
Cyclophosphamide Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 50-18-0, 6055-19-2 2907
20
Fludarabine Approved Phase 2, Phase 3, Phase 1, Early Phase 1 21679-14-1, 75607-67-9 30751
21
Vidarabine Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 24356-66-9 21704 32326
22
Darbepoetin alfa Approved, Investigational Phase 2, Phase 3 209810-58-2, 11096-26-7
23
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
24
Nandrolone Approved, Experimental, Illicit, Investigational Phase 3,Phase 1,Phase 2 62-90-8, 434-22-0 9904 229455
25
Nandrolone decanoate Approved, Illicit Phase 3,Phase 1,Phase 2 360-70-3 9677
26
Ephedrine Approved Phase 3 299-42-3 9294
27
Pseudoephedrine Approved Phase 3 90-82-4 7028
28
Iodine Approved, Investigational Phase 3 7553-56-2 807
29 Alkylating Agents Phase 2, Phase 3, Phase 1, Early Phase 1
30 Anti-Infective Agents Phase 2, Phase 3, Phase 1, Early Phase 1
31 Antimetabolites Phase 2, Phase 3, Phase 1, Early Phase 1
32 Antimetabolites, Antineoplastic Phase 2, Phase 3, Phase 1, Early Phase 1
33 Antiviral Agents Phase 2, Phase 3, Phase 1, Early Phase 1
34 Adjuvants, Immunologic Phase 2, Phase 3
35 Epoetin alfa Phase 2, Phase 3 113427-24-0
36 Hematinics Phase 2, Phase 3
37 Pharmaceutical Solutions Phase 2, Phase 3, Phase 1
38 Antifungal Agents Phase 3,Phase 2,Phase 1
39 Calcineurin Inhibitors Phase 3,Phase 2,Phase 1
40 Dermatologic Agents Phase 3,Phase 2,Phase 1
41 Anabolic Agents Phase 3,Phase 1,Phase 2
42 Androgens Phase 3,Phase 1,Phase 2
43 Hormone Antagonists Phase 3,Phase 2,Phase 1
44 Hormones Phase 3,Phase 2,Phase 1
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
46 Autonomic Agents Phase 3,Phase 2,Phase 1
47 Nasal Decongestants Phase 3
48 Ophthalmic Solutions Phase 3
49 Respiratory System Agents Phase 3
50 Tetrahydrozoline Phase 3

Interventional clinical trials:

(show top 50) (show all 150)

# Name Status NCT ID Phase Drugs
1 Different Doses of Anti-thymocyte Globin to Treat Child Severe Aplastic Anemia Unknown status NCT01997372 Phase 4 ATG
2 Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL Completed NCT02314273 Phase 4 rhIL-11
3 Study Evaluating the Efficacy of Enbrel (Etanercept) in Subjects in Japan Completed NCT00503503 Phase 4 Enbrel (etanercept)
4 Eltrombopag in Children With Idiopathic Aplastic Anemia Not yet recruiting NCT03243656 Phase 4 Eltrombopag
5 The Impact of Red Cell Age on Product Utilization in the Chronically Transfused Outpatient Population Unknown status NCT02393508 Phase 3
6 Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases Unknown status NCT01019876 Phase 2, Phase 3 Fludarabine;Cyclophosphamide;Cyclophosphamide 40;Cyclophosphamide 30
7 Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS) Unknown status NCT00234143 Phase 2, Phase 3 Darbepoetin
8 Comparison of Cy-Atg vs Flu-Atg for the Conditioning Therapy in Allo-HCT for Adult Aplastic Anemia Unknown status NCT01145976 Phase 3 Cy-ATG;Flu-ATG
9 Stem Cell Transplant for Bone Marrow Failure Syndromes Completed NCT00176878 Phase 2, Phase 3 Fludarabine monophosphate;Busulfan
10 Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT Completed NCT00774527 Phase 3 Cyclophosphamide-fludarabine-anti thymocyte globulin
11 Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder Completed NCT00755040 Phase 3 cyclosporine ophthalmic emulsion
12 Multi-Center Trial of Anti-Thymocyte Globulin in Treatment of Aplastic Anemia and Other Hematologic Disorders Completed NCT00000597 Phase 3 antilymphocyte serum;nandrolone
13 Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Completed NCT00098280 Phase 3 Eculizumab
14 A Study Evaluating Epoetin Alfa 40,000 IU (International Units) Every Week or 80,000 IU Every Week Compared to Placebo in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes at Risk for Transfusion Terminated NCT00695396 Phase 3 Placebo;Epoetin alfa;Placebo;Epoetin alfa
15 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013) Unknown status NCT01760096 Phase 2 Levamisole+cyclosporin A+Glucocorticoids;cyclosporin A+Glucocorticoids;Glucocorticoids
16 Nandrolone Decanoate in the Treatment of Telomeropathies Unknown status NCT02055456 Phase 1, Phase 2 Nandrolone Decanoate
17 Eltrombopag for Enhancing Platelet Engraftment in Adult Patients Undergoing Cord Blood Transplantation Unknown status NCT01757145 Phase 2 Eltrombopag
18 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria Unknown status NCT01642979 Phase 2 Levamisole+cyclosporin A+Glucocorticoids;cyclosporin A+Glucocorticoids;Glucocorticoids
19 Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia Completed NCT00065260 Phase 2 Campath-1H;r-ATG;CsA
20 Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome Completed NCT00731328 Phase 2
21 Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes Completed NCT00004143 Phase 2 Campath, Chemo and/or TBI Allo SCT
22 Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia Completed NCT00260689 Phase 2 Cyclosporine;Alemtuzumab
23 Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes Completed NCT00004787 Phase 2 filgrastim
24 A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia Completed NCT01187017 Phase 1, Phase 2 Cyclophosphamide;Fludarabine
25 Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia Completed NCT01193283 Phase 1, Phase 2 Cyclophosphamide;Cyclosporine
26 Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases Completed NCT02277639 Phase 2
27 Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia Completed NCT00061360 Phase 2 Sirolimus (Rapamune)
28 Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003270 Phase 2 busulfan;cyclophosphamide;cyclosporine;methylprednisolone
29 Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer Completed NCT00002809 Phase 2 cyclophosphamide;methotrexate;tacrolimus
30 Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases Completed NCT00003662 Phase 2 busulfan;cyclophosphamide;cyclosporine;melphalan;methylprednisolone
31 Bortezomib to Treat Significant Complication of HSCT Completed NCT01929980 Phase 2 Bortezomib
32 Danazol for Genetic Bone Marrow and Lung Disorders Completed NCT01441037 Phase 1, Phase 2 Danazol
33 Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 Completed NCT00479115 Phase 1, Phase 2 AMD3100
34 Doxercalciferol in Treating Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia Completed NCT00052832 Phase 2
35 High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study Completed NCT00288626 Phase 2 Granulocyte-colony stimulating factor (G-CSF) and prednisone;Carmustine, etoposide, cytarabine, and melphalan (BEAM)
36 Antithymocyte Globulin and Cyclosporine to Treat Myelodysplasia Completed NCT00005937 Phase 2 Antithymocyte globulin;Cyclosporine
37 Study of the Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes Completed NCT00840827 Phase 2 lenalidomide;cyclosporine A
38 Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia Completed NCT00011505 Phase 2 G-CSF
39 Combination Therapy of Severe Aplastic Anemia Completed NCT00001964 Phase 2 Cyclosporine
40 Idarubicin, Cytarabine, and Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome Completed NCT00077116 Phase 2 busulfan;cyclophosphamide;cytarabine;gemtuzumab ozogamicin;idarubicin
41 Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation Completed NCT02337595 Phase 1, Phase 2
42 Mycophenolate Mofetil and Cyclosporine to Treat Relapsing Aplastic Anemia Completed NCT00005935 Phase 2 Mycophenolate mofetil;Cyclosporine
43 Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia Completed NCT00229619 Phase 2 Rituximab
44 Combination Study of Deferasirox and Erythropoietin in Patients With Low- and Int-1-risk Myelodysplastic Syndrome. Completed NCT01868477 Phase 2 Erythropoietin alpha;Erythropoietin alpha;Deferasirox
45 Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells Recruiting NCT01174108 Phase 2
46 Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia Recruiting NCT02224872 Phase 2 Thymoglobulin;Fludarabine;Cyclophosphamide;Mesna;Tacrolimus;Mycophenolic acid mofetil
47 Limiting Chemotherapy Side Effects by Using Moxa Recruiting NCT02781155 Phase 1, Phase 2
48 Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita Recruiting NCT01659606 Phase 2 Fludarabine;Cyclosporins;Mycophenolate mofetil
49 Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia Recruiting NCT02828592 Phase 2 Fludarabine;Cyclophosphamide;Rabbit ATG;Cyclophosphamide
50 NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia Recruiting NCT02833805 Phase 2 Thymoglobulin;Fludarabine;Cyclophosphamide;Tacrolimus;Mycophenolate mofetil

Search NIH Clinical Center for Pancytopenia

Cochrane evidence based reviews: pancytopenia

Genetic Tests for Pancytopenia

Genetic tests related to Pancytopenia:

# Genetic test Affiliating Genes
1 Pancytopenia 28

Anatomical Context for Pancytopenia

MalaCards organs/tissues related to Pancytopenia:

38
Bone, Bone Marrow, T Cells, Myeloid, Liver, Lung, Eye

Publications for Pancytopenia

Articles related to Pancytopenia:

(show top 50) (show all 706)
# Title Authors Year
1
Pancytopenia and Myelodysplastic Changes in Aceruloplasminemia: A Case with a Novel Pathogenic Variant in the Ceruloplasmin Gene. ( 29434149 )
2018
2
CD41 immune staining of micromegakaryocytes improves the diagnosis of myelodysplastic syndrome and differentiation from pancytopenia. ( 29353154 )
2018
3
Answer to Photo Quiz: Pancytopenia in a young girl with skin lesions. ( 29380734 )
2018
4
Pancytopenia and megaloblastic erythropoiesis reveal a novel GIF mutation. ( 29368379 )
2018
5
Pancytopenia in a young girl with skin lesions. ( 29380733 )
2018
6
Smear Campaign: Misattribution of Pancytopenia to a Tick-Borne Illness. ( 29273895 )
2017
7
High-Dose Filgrastim Treatment of Nonregenerative Pancytopenia Associated With Chronic Canine Ehrlichiosis. ( 28750787 )
2017
8
Case 20-2017 - A 48-Year-Old Man with Weight Loss, Confusion, Skin Lesions, and Pancytopenia. ( 28657866 )
2017
9
Mutations in EFL1, an SBDS partner, are associated with infantile pancytopenia, exocrine pancreatic insufficiency and skeletal anomalies in aShwachman-Diamond like syndrome. ( 28331068 )
2017
10
From febrile pancytopenia to hemophagocytic lymphohistiocytosis-associated organ dysfunction. ( 28649693 )
2017
11
Feeling run down: exercise-induced pancytopenia. ( 28419423 )
2017
12
Azathioprine-Induced Pancytopenia and Septic Complications: A Probable Cause of Death. ( 28874083 )
2017
13
Case Report of an Adolescent Male With Unexplained Pancytopenia:<i>GATA2</i>-Associated Bone Marrow Failure and Genetic Testing. ( 29230432 )
2017
14
A Howling Cause of Pancytopenia. ( 29069118 )
2017
15
Successful haploidentical BMT with post-transplant cyclophosphamide for refractory autoimmune pancytopenia after cord blood transplant in pediatric myelodysplastic syndrome. ( 28067878 )
2017
16
Fever and Pancytopenia in a Liver Transplant Recipient: Going Against the Rules of Occam's Razor. ( 28706972 )
2017
17
Suspected immune-mediated neutropenia and corticosteroid responsive pancytopenia in a Portuguese water dog. ( 28042161 )
2017
18
Hypocobalaminaemia as a cause of bone marrow failure and pancytopenia in a cat. ( 28444757 )
2017
19
Unusual case of splenomegaly and pancytopenia in a returned traveller. ( 29105271 )
2017
20
Case report: An HIV+ patient presenting with pancytopenia, hepatic failure, and coagulopathy; a rare small cell liver carcinoma with diffuse splenic and bone marrow metastasis diagnosed at autopsy. ( 28935394 )
2017
21
Pancytopenia and Fever of Unknown Origin in a 12-Year-Old Boy. ( 29073781 )
2017
22
The risks of using allogeneic cell lines for vaccine production: the example of Bovine Neonatal Pancytopenia. ( 27744721 )
2017
23
Herd-level animal management factors associated with the occurrence of bovine neonatal pancytopenia in calves in a multi-country study. ( 28678850 )
2017
24
Mixed Malarial Infection with Pancytopenia in a Child with Acute Lymphoblastic Leukemia: An Unusual Presentation. ( 28469349 )
2017
25
Case report: patient with unexplained high fever and pancytopenia. ( 28521652 )
2017
26
Pembrolizumab-Induced Pancytopenia: A Case Report. ( 28746020 )
2017
27
Clinicohematological Study of Pancytopenia in a Tertiary Care Hospital of Western Region of Nepal. ( 29255313 )
2017
28
Pancytopenia and Hypothyroidism in a Patient With Leukemic Infiltration of the Thyroid as the First Presentation of Acute Lymphoblastic Leukemia. ( 28562510 )
2017
29
Chronic steroid-response pancytopenia and increased bone density due to thromboxane synthase deficiency. ( 28868793 )
2017
30
Sjogren's syndrome complicating pancytopenia, cerebral hemorrhage, and damage in nervous system: A case report and literature review. ( 29390256 )
2017
31
Ataxia-pancytopenia syndrome with SAMD9L mutations. ( 28852709 )
2017
32
Screening novel autoantigens targeted by serum IgG autoantibodies in immunorelated pancytopenia by SEREX. ( 28687989 )
2017
33
A Young Woman With an Erythematous Rash, Fever, Tachycardia, and Pancytopenia. ( 28654467 )
2017
34
A 28-year-old woman with fever, rash, and pancytopenia. ( 28668113 )
2017
35
IVIG-Associated Maternal Pancytopenia during Treatment for Neonatal Alloimmune Thrombocytopenia. ( 28970962 )
2017
36
Chilblain lupus and steroid-responsive pancytopenia precede monosomy 7-linked AML as manifestation of rasopathy. ( 28802089 )
2017
37
Case 1: A newborn with pancytopenia. ( 26941551 )
2016
38
A Case of Copper Deficiency-Induced Pancytopenia With Maintenance Hemodialysis Outpatient Treated With Polaprezinc. ( 26948531 )
2016
39
Immune pancytopenia after chemotherapy in a patient with diffuse large B-cell lymphoma. ( 27651408 )
2016
40
Acute Lymphoblastic Leukemia Presenting With Pancytopenia Followed by a 14-Month-Long Period of Transient Remission Possibly Supporting the Adrenal Hypothesis of Leukemogenesis. ( 27509378 )
2016
41
Pancytopenia associated with levetiracetam in an epileptic woman. ( 27927707 )
2016
42
A man in his 30s with ulcerative colitis and pancytopenia. ( 27325035 )
2016
43
Novel Developments in Leukopenia and Pancytopenia. ( 27866577 )
2016
44
An Unusual Case of Acute Promyelocytic Leukemia Presenting With Hypoplastic Bone Marrow and Pancytopenia. ( 26992265 )
2016
45
Methotrexate-induced nonhealing cutaneous ulcers in a nonpsoriatic patient without pancytopenia. ( 27730043 )
2016
46
Fanconi anemia in 55-year-old identical twins first presenting as fatal post-chemotherapy pancytopenia. ( 27427815 )
2016
47
Mucocutaneous Ulcerations and Pancytopenia due to Methotrexate Overdose. ( 27920680 )
2016
48
Zotepine-associated vitamin B12 deficiency and pancytopenia. ( 27872328 )
2016
49
Acute Hepatitis and Pancytopenia in Healthy Infant with Adenovirus. ( 27340581 )
2016
50
Pancytopenia During Parenteral Nutrition. ( 27167899 )
2016

Variations for Pancytopenia

Expression for Pancytopenia

Search GEO for disease gene expression data for Pancytopenia.

Pathways for Pancytopenia

GO Terms for Pancytopenia

Cellular components related to Pancytopenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 telomerase holoenzyme complex GO:0005697 8.62 DKC1 TERT

Biological processes related to Pancytopenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of receptor activity GO:0010469 9.65 CSF1 CSF2 CSF3 EPO THPO
2 positive regulation of Ras protein signal transduction GO:0046579 9.48 CSF1 EPO
3 telomere maintenance via telomerase GO:0007004 9.46 DKC1 TERT
4 positive regulation of nitric-oxide synthase activity GO:0051000 9.43 DHFR TERT
5 macrophage differentiation GO:0030225 9.4 CSF1 CSF3
6 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.37 CSF1 CSF2
7 DNA ligation GO:0006266 9.32 LIG4 MGMT
8 neutrophil differentiation GO:0030223 9.16 CSF2 CSF3
9 cell proliferation GO:0008283 9.1 CSF1 DKC1 EPO LIG4 MPL THPO
10 thrombopoietin-mediated signaling pathway GO:0038163 8.96 MPL THPO

Molecular functions related to Pancytopenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 telomerase RNA binding GO:0070034 9.26 DKC1 TERT
2 growth factor activity GO:0008083 9.26 CSF1 CSF2 CSF3 THPO
3 telomerase activity GO:0003720 9.16 DKC1 TERT
4 cytokine activity GO:0005125 9.02 CSF1 CSF2 CSF3 EPO THPO

Sources for Pancytopenia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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