Aliases & Classifications for Pancytopenia

MalaCards integrated aliases for Pancytopenia:

Name: Pancytopenia 12 29 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:12450
ICD10 33 D61.81
ICD9CM 35 284.1
MeSH 42 D010198
UMLS 69 C0030312

Summaries for Pancytopenia

MalaCards based summary : Pancytopenia is related to thrombocytopenia, congenital amegakaryocytic and hemolytic anemia. An important gene associated with Pancytopenia is SAMD9L (Sterile Alpha Motif Domain Containing 9 Like), and among its related pathways/superpathways are Chks in Checkpoint Regulation and Jak-STAT signaling pathway (KEGG). The drugs Benzocaine and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and t cells, and related phenotypes are Increased viability with MLN4924 (a NAE inhibitor) and hematopoietic system

Wikipedia : 72 Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood... more...

Related Diseases for Pancytopenia

Diseases related to Pancytopenia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 296)
id Related Disease Score Top Affiliating Genes
1 thrombocytopenia, congenital amegakaryocytic 31.2 MPL THPO
2 hemolytic anemia 27.9 CSF2 CSF3 MPL THPO
3 ataxia-pancytopenia syndrome 12.2
4 samd9l-related ataxia-pancytopenia syndrome 11.9
5 fanconi anemia, complementation group a 11.6
6 dyskeratosis congenita 11.3
7 aplastic anemia 11.1
8 hemophagocytic lymphohistiocytosis 11.0
9 fanconi-like syndrome 11.0
10 dyskeratosis congenita, x-linked 10.9
11 sackey sakati aur syndrome 10.9
12 fanconi anemia, complementation group d2 10.9
13 fanconi anemia, complementation group c 10.9
14 fanconi anemia, complementation group b 10.9
15 radioulnar synostosis with amegakaryocytic thrombocytopenia 2 10.8
16 cerebroretinal microangiopathy with calcifications and cysts 2 10.8
17 bone marrow failure syndrome 3 10.8
18 immunodeficiency, common variable, 13 10.7
19 evans' syndrome 10.7
20 bone marrow failure syndrome 2 10.7
21 osteopetrosis, autosomal recessive 5 10.6
22 osteopetrosis, autosomal recessive 1 10.6
23 lymphoproliferative syndrome, x-linked, 2 10.6
24 radioulnar synostosis with amegakaryocytic thrombocytopenia 1 10.6
25 methylmalonyl-coa epimerase deficiency 10.6
26 osteopetrosis, autosomal recessive 2 10.6
27 lig4 syndrome 10.6
28 osteopetrosis, autosomal recessive 3, with renal tubular acidosis 10.6
29 osteopetrosis, autosomal recessive 4 10.6
30 osteopetrosis, autosomal dominant 2 10.6
31 virus associated hemophagocytic syndrome 10.6
32 osteopetrosis 10.6
33 dyskeratosis congenita, autosomal recessive 3 10.6
34 hemophagocytic lymphohistiocytosis, familial, 2 10.6
35 osteopetrosis, autosomal recessive 6 10.6
36 osteopetrosis, autosomal recessive 7 10.6
37 transaldolase deficiency 10.6
38 megaloblastic anemia due to dihydrofolate reductase deficiency 10.6
39 transcobalamin ii deficiency 10.6
40 lymphoproliferative syndrome 1 10.6
41 osteopetrosis, autosomal dominant 1 10.6
42 lymphoproliferative syndrome, x-linked, 1 10.6
43 dysmorphism cleft palate loose skin 10.5 DKC1 TERT
44 fibromatosis, gingival, 4 10.4 FANCA FANCC FANCG
45 antiphospholipid syndrome, familial 10.4 FANCA FANCC FANCG
46 mental retardation, x-linked 49/15 10.4 FANCA FANCC FANCG
47 cantu sanchez-corona fragoso syndrome 10.4 CSF2 DHFR
48 enterovesical fistula 10.4 CSF2 CSF3
49 primary systemic mycosis 10.4 CSF2 CSF3
50 neutropenia, severe congenital 3, autosomal recessive 10.4 CSF2 CSF3

Graphical network of the top 20 diseases related to Pancytopenia:



Diseases related to Pancytopenia

Symptoms & Phenotypes for Pancytopenia

GenomeRNAi Phenotypes related to Pancytopenia according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-3 9.02 DHFR FANCA FANCC FANCG MGMT

MGI Mouse Phenotypes related to Pancytopenia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.25 CSF1 CSF2 CSF3 DKC1 EPO FANCA
2 homeostasis/metabolism MP:0005376 10.18 CSF1 CSF2 DKC1 EPO FANCA MGMT
3 cellular MP:0005384 10.11 MPL TERT CSF1 CSF2 DKC1 EPO
4 immune system MP:0005387 10.11 CSF2 CSF3 DKC1 EPO FANCC MPL
5 mortality/aging MP:0010768 10 TERT TPMT CSF1 CSF2 DHFR DKC1
6 integument MP:0010771 9.8 CSF1 CSF2 CSF3 DKC1 EPO SAMD9L
7 neoplasm MP:0002006 9.63 CSF2 DKC1 FANCA MGMT SAMD9L TERT
8 reproductive system MP:0005389 9.56 FANCG TERT TPMT CSF1 CSF2 DKC1
9 respiratory system MP:0005388 9.1 CSF1 CSF2 DKC1 EPO MGMT TERT

Drugs & Therapeutics for Pancytopenia

Drugs for Pancytopenia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 170)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
2
Lenograstim Approved Phase 4,Phase 2,Phase 3 135968-09-1
3
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 1 53-03-2 5865
4
Oprelvekin Approved, Investigational Phase 4 145941-26-0
5
Etanercept Approved, Investigational Phase 4 185243-69-0
6 tannic acid Approved, Nutraceutical Phase 4,Phase 2
7 Cyclosporins Phase 4,Phase 3,Phase 2,Phase 1
8 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
9 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
10 Antilymphocyte Serum Phase 4,Phase 3,Phase 2,Phase 1
11 Analgesics Phase 4
12 Analgesics, Non-Narcotic Phase 4
13 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 1
14 Anti-Inflammatory Agents, Non-Steroidal Phase 4
15 Gastrointestinal Agents Phase 4,Phase 2,Phase 1
16 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
17
alemtuzumab Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 216503-57-0
18
Busulfan Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 55-98-1 2478
19
Cyclophosphamide Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 50-18-0, 6055-19-2 2907
20
Fludarabine Approved Phase 2, Phase 3, Phase 1, Early Phase 1 21679-14-1, 75607-67-9 30751
21
Vidarabine Approved Phase 2, Phase 3, Phase 1, Early Phase 1 24356-66-9 32326 21704
22
Darbepoetin alfa Approved, Investigational Phase 2, Phase 3 11096-26-7, 209810-58-2
23
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
24
Ephedrine Approved Phase 3 299-42-3 9294
25
Pseudoephedrine Approved Phase 3 90-82-4 7028
26
Nandrolone Approved, Experimental, Illicit Phase 3,Phase 1,Phase 2 434-22-0, 62-90-8 9904 229455
27
Nandrolone decanoate Approved, Illicit Phase 3,Phase 1,Phase 2 360-70-3 9677
28
Iodine Investigational Phase 3 7553-56-2 807
29 Alkylating Agents Phase 2, Phase 3, Phase 1, Early Phase 1
30 Anti-Infective Agents Phase 2, Phase 3, Phase 1, Early Phase 1
31 Antimetabolites Phase 2, Phase 3, Phase 1, Early Phase 1
32 Antimetabolites, Antineoplastic Phase 2, Phase 3, Phase 1, Early Phase 1
33 Antiviral Agents Phase 2, Phase 3, Phase 1, Early Phase 1
34 Adjuvants, Immunologic Phase 2, Phase 3
35 Epoetin alfa Phase 2, Phase 3 113427-24-0
36 Hematinics Phase 2, Phase 3
37 Pharmaceutical Solutions Phase 2, Phase 3, Phase 1
38 Antifungal Agents Phase 3,Phase 2,Phase 1
39 Calcineurin Inhibitors Phase 3,Phase 2,Phase 1
40 Dermatologic Agents Phase 3,Phase 2,Phase 1
41 Hormone Antagonists Phase 3,Phase 2,Phase 1
42 Hormones Phase 3,Phase 2,Phase 1
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
44 Autonomic Agents Phase 3,Phase 2,Phase 1
45 Nasal Decongestants Phase 3
46 Ophthalmic Solutions Phase 3
47 Respiratory System Agents Phase 3
48 Tetrahydrozoline Phase 3
49 Vasoconstrictor Agents Phase 3
50 Anabolic Agents Phase 3,Phase 1,Phase 2

Interventional clinical trials:

(show top 50) (show all 147)

id Name Status NCT ID Phase Drugs
1 Different Doses of Anti-thymocyte Globin to Treat Child Severe Aplastic Anemia Unknown status NCT01997372 Phase 4 ATG
2 Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL Completed NCT02314273 Phase 4 rhIL-11
3 Study Evaluating the Efficacy of Enbrel (Etanercept) in Subjects in Japan Completed NCT00503503 Phase 4 Enbrel (etanercept)
4 Eltrombopag in Children With Idiopathic Aplastic Anemia Not yet recruiting NCT03243656 Phase 4 Eltrombopag
5 Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases Unknown status NCT01019876 Phase 2, Phase 3 Fludarabine;Cyclophosphamide;Cyclophosphamide 40;Cyclophosphamide 30
6 Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS) Unknown status NCT00234143 Phase 2, Phase 3 Darbepoetin
7 Comparison of Cy-Atg vs Flu-Atg for the Conditioning Therapy in Allo-HCT for Adult Aplastic Anemia Unknown status NCT01145976 Phase 3 Cy-ATG;Flu-ATG
8 Stem Cell Transplant for Bone Marrow Failure Syndromes Completed NCT00176878 Phase 2, Phase 3 Fludarabine monophosphate;Busulfan
9 Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT Completed NCT00774527 Phase 3 Cyclophosphamide-fludarabine-anti thymocyte globulin
10 Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder Completed NCT00755040 Phase 3 cyclosporine ophthalmic emulsion
11 Multi-Center Trial of Anti-Thymocyte Globulin in Treatment of Aplastic Anemia and Other Hematologic Disorders Completed NCT00000597 Phase 3 antilymphocyte serum;nandrolone
12 Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Completed NCT00098280 Phase 3 Eculizumab
13 The Impact of Red Cell Age on Product Utilization in the Chronically Transfused Outpatient Population Enrolling by invitation NCT02393508 Phase 3
14 A Study Evaluating Epoetin Alfa 40,000 IU (International Units) Every Week or 80,000 IU Every Week Compared to Placebo in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes at Risk for Transfusion Terminated NCT00695396 Phase 3 Placebo;Epoetin alfa;Placebo;Epoetin alfa
15 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013) Unknown status NCT01760096 Phase 2 Levamisole+cyclosporin A+Glucocorticoids;cyclosporin A+Glucocorticoids;Glucocorticoids
16 Eltrombopag for Enhancing Platelet Engraftment in Adult Patients Undergoing Cord Blood Transplantation Unknown status NCT01757145 Phase 2 Eltrombopag
17 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria Unknown status NCT01642979 Phase 2 Levamisole+cyclosporin A+Glucocorticoids;cyclosporin A+Glucocorticoids;Glucocorticoids
18 Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia Completed NCT00065260 Phase 2 Campath-1H;r-ATG;CsA
19 Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome Completed NCT00731328 Phase 2
20 Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes Completed NCT00004143 Phase 2 Campath, Chemo and/or TBI Allo SCT
21 Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia Completed NCT00260689 Phase 2 Cyclosporine;Alemtuzumab
22 Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes Completed NCT00004787 Phase 2 filgrastim
23 A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia Completed NCT01187017 Phase 1, Phase 2 Cyclophosphamide;Fludarabine
24 Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia Completed NCT01193283 Phase 1, Phase 2 Cyclophosphamide;Cyclosporine
25 Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases Completed NCT02277639 Phase 2
26 Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia Completed NCT00061360 Phase 2 Sirolimus (Rapamune)
27 Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer Completed NCT00002809 Phase 2 cyclophosphamide;methotrexate;tacrolimus
28 Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases Completed NCT00003662 Phase 2 busulfan;cyclophosphamide;cyclosporine;melphalan;methylprednisolone
29 Bortezomib to Treat Significant Complication of HSCT Completed NCT01929980 Phase 2 Bortezomib
30 Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 Completed NCT00479115 Phase 1, Phase 2 AMD3100
31 Danazol for Genetic Bone Marrow and Lung Disorders Completed NCT01441037 Phase 1, Phase 2 Danazol
32 Doxercalciferol in Treating Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia Completed NCT00052832 Phase 2
33 Antithymocyte Globulin and Cyclosporine to Treat Myelodysplasia Completed NCT00005937 Phase 2 Antithymocyte globulin;Cyclosporine
34 High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study Completed NCT00288626 Phase 2 Granulocyte-colony stimulating factor (G-CSF) and prednisone;Carmustine, etoposide, cytarabine, and melphalan (BEAM)
35 Study of the Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes Completed NCT00840827 Phase 2 lenalidomide;cyclosporine A
36 Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia Completed NCT00011505 Phase 2 G-CSF
37 Combination Therapy of Severe Aplastic Anemia Completed NCT00001964 Phase 2 Cyclosporine
38 Idarubicin, Cytarabine, and Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome Completed NCT00077116 Phase 2 busulfan;cyclophosphamide;cytarabine;gemtuzumab ozogamicin;idarubicin
39 Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation Completed NCT02337595 Phase 1, Phase 2
40 Mycophenolate Mofetil and Cyclosporine to Treat Relapsing Aplastic Anemia Completed NCT00005935 Phase 2 Mycophenolate mofetil;Cyclosporine
41 Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia Completed NCT00229619 Phase 2 Rituximab
42 Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells Recruiting NCT01174108 Phase 2
43 Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia Recruiting NCT02224872 Phase 2 Thymoglobulin;Fludarabine;Cyclophosphamide;Mesna;Tacrolimus;Mycophenolic acid mofetil
44 Limiting Chemotherapy Side Effects by Using Moxa Recruiting NCT02781155 Phase 1, Phase 2
45 Nandrolone Decanoate in the Treatment of Telomeropathies Recruiting NCT02055456 Phase 1, Phase 2 Nandrolone Decanoate
46 Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita Recruiting NCT01659606 Phase 2 Fludarabine;Cyclosporins;Mycophenolate mofetil
47 Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia Recruiting NCT02828592 Phase 2 Fludarabine;Cyclophosphamide;Rabbit ATG;Cyclophosphamide
48 NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia Recruiting NCT02833805 Phase 2 Thymoglobulin;Fludarabine;Cyclophosphamide;Tacrolimus;Mycophenolate mofetil
49 A Single-Arm Phase 2 Study With Optimized Standard Protocol for Severe Aplastic Anemia Recruiting NCT02203396 Phase 2 rabbit ATG, Cyclosporine, Levamisole
50 Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders Recruiting NCT00919503 Phase 2 Cyclosporine;Fludarabine Phosphate;Methotrexate;Mycophenolate Mofetil;Tacrolimus;Treosulfan

Search NIH Clinical Center for Pancytopenia

Cochrane evidence based reviews: pancytopenia

Genetic Tests for Pancytopenia

Genetic tests related to Pancytopenia:

id Genetic test Affiliating Genes
1 Pancytopenia 29

Anatomical Context for Pancytopenia

MalaCards organs/tissues related to Pancytopenia:

39
Bone, Bone Marrow, T Cells, Myeloid, Liver, Lung, Eye

Publications for Pancytopenia

Articles related to Pancytopenia:

(show top 50) (show all 693)
id Title Authors Year
1
Herd-level animal management factors associated with the occurrence of bovine neonatal pancytopenia in calves in a multi-country study. ( 28678850 )
2017
2
A 28-year-old woman with fever, rash, and pancytopenia. ( 28668113 )
2017
3
Feeling run down: exercise-induced pancytopenia. ( 28419423 )
2017
4
Mutations in EFL1, an SBDS partner, are associated with infantile pancytopenia, exocrine pancreatic insufficiency and skeletal anomalies in aShwachman-Diamond like syndrome. ( 28331068 )
2017
5
Mixed Malarial Infection with Pancytopenia in a Child with Acute Lymphoblastic Leukemia: An Unusual Presentation. ( 28469349 )
2017
6
Pancytopenia and Hypothyroidism in a Patient With Leukemic Infiltration of the Thyroid as the First Presentation of Acute Lymphoblastic Leukemia. ( 28562510 )
2017
7
High-Dose Filgrastim Treatment of Nonregenerative Pancytopenia Associated With Chronic Canine Ehrlichiosis. ( 28750787 )
2017
8
Chronic steroid-response pancytopenia and increased bone density due to thromboxane synthase deficiency. ( 28868793 )
2017
9
From febrile pancytopenia to hemophagocytic lymphohistiocytosis-associated organ dysfunction. ( 28649693 )
2017
10
Suspected immune-mediated neutropenia and corticosteroid responsive pancytopenia in a Portuguese water dog. ( 28042161 )
2017
11
Ataxia-pancytopenia syndrome with SAMD9L mutations. ( 28852709 )
2017
12
Case report: patient with unexplained high fever and pancytopenia. ( 28521652 )
2017
13
Chilblain lupus and steroid-responsive pancytopenia precede monosomy 7-linked AML as manifestation of rasopathy. ( 28802089 )
2017
14
Azathioprine-Induced Pancytopenia and Septic Complications: A Probable Cause of Death. ( 28874083 )
2017
15
Fever and Pancytopenia in a Liver Transplant Recipient: Going Against the Rules of Occam's Razor. ( 28706972 )
2017
16
Case 20-2017 - A 48-Year-Old Man with Weight Loss, Confusion, Skin Lesions, and Pancytopenia. ( 28657866 )
2017
17
Pembrolizumab-Induced Pancytopenia: A Case Report. ( 28746020 )
2017
18
Screening novel autoantigens targeted by serum IgG autoantibodies in immunorelated pancytopenia by SEREX. ( 28687989 )
2017
19
Successful haploidentical BMT with post-transplant cyclophosphamide for refractory autoimmune pancytopenia after cord blood transplant in pediatric myelodysplastic syndrome. ( 28067878 )
2017
20
Hypocobalaminaemia as a cause of bone marrow failure and pancytopenia in a cat. ( 28444757 )
2017
21
The risks of using allogeneic cell lines for vaccine production: the example of Bovine Neonatal Pancytopenia. ( 27744721 )
2017
22
Case report: An HIV+ patient presenting with pancytopenia, hepatic failure, and coagulopathy; a rare small cell liver carcinoma with diffuse splenic and bone marrow metastasis diagnosed at autopsy. ( 28935394 )
2017
23
A Young Woman With an Erythematous Rash, Fever, Tachycardia, and Pancytopenia. ( 28654467 )
2017
24
Pregnancy boosts vaccine-induced Bovine Neonatal Pancytopenia-associated alloantibodies. ( 26796141 )
2016
25
Bovine Neonatal Pancytopenia - correlation between clinical symptoms, hematological parameters and lifespan. ( 27805246 )
2016
26
Bone Marrow Oxalosis in a Patient With Pancytopenia Following Bilateral Nephrectomy. ( 26915618 )
2016
27
Mucocutaneous Ulcerations and Pancytopenia due to Methotrexate Overdose. ( 27920680 )
2016
28
Significance of myelodysplastic syndrome-associated somatic variants in the evaluation of patients with pancytopenia and idiopathic cytopenias of undetermined significance. ( 27255165 )
2016
29
Neuromyelitis optica accompanied by nephrotic syndrome and autoimmune-related pancytopenia. ( 27237748 )
2016
30
Pancytopenia caused by visceral leishmaniasis in a patient immunosuppressed after cancer therapy. ( 27811190 )
2016
31
Immune pancytopenia after chemotherapy in a patient with diffuse large B-cell lymphoma. ( 27651408 )
2016
32
A man in his 30s with ulcerative colitis and pancytopenia. ( 27325035 )
2016
33
Methotrexate-induced nonhealing cutaneous ulcers in a nonpsoriatic patient without pancytopenia. ( 27730043 )
2016
34
Acute Hepatitis and Pancytopenia in Healthy Infant with Adenovirus. ( 27340581 )
2016
35
Correlation of Antiglobulin Reactivity and Severity of Pancytopenia in a Patient with Hemophagocytic Lymphohistiocytosis: A Case Report and Review of Literature. ( 27610283 )
2016
36
Idiopathic Fatal Pancytopenia: A Case Report. ( 27504300 )
2016
37
Novel Developments in Leukopenia and Pancytopenia. ( 27866577 )
2016
38
Comment on published article in Lupus: Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil; IVIG in myelofibrosis in SLE. ( 27480990 )
2016
39
Stuck with pancytopenia in dengue fever: Evoke for hemophagocytic syndrome. ( 26955219 )
2016
40
Severe pancytopenia due to acute folate deficiency despite normal folate erythrocyte level. ( 27108778 )
2016
41
Fanconi anemia in 55-year-old identical twins first presenting as fatal post-chemotherapy pancytopenia. ( 27427815 )
2016
42
Extra pulmonary tuberculosis presenting as fever with massive splenomegaly and pancytopenia. ( 27051579 )
2016
43
Pancytopenia and Severe Gastrointestinal Toxicities Associated with 5-Fluorouracil in a Patient with Thymidylate Synthase (TYMS) Polymorphism. ( 27774364 )
2016
44
A case of asymptomatic pancytopenia with clinical features of hemolysis as a presentation of pernicious anemia. ( 27609735 )
2016
45
Rare case of sarcoidosis presenting with pancytopenia, acute renal failure and hypercalcaemia. ( 26989117 )
2016
46
Zotepine-associated vitamin B12 deficiency and pancytopenia. ( 27872328 )
2016
47
Rapidly progressive autoimmune pancytopenia successfully treated with steroids. ( 27941280 )
2016
48
Pure Red Cell Aplasia in Major ABO-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with Severe Pancytopenia. ( 26921820 )
2016
49
Wuchereria bancrofti: Unusual Presentation as Pancytopenia. ( 27630856 )
2016
50
Pancytopenia associated with levetiracetam in an epileptic woman. ( 27927707 )
2016

Variations for Pancytopenia

Expression for Pancytopenia

Search GEO for disease gene expression data for Pancytopenia.

Pathways for Pancytopenia

GO Terms for Pancytopenia

Cellular components related to Pancytopenia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 telomerase holoenzyme complex GO:0005697 8.96 DKC1 TERT
2 Fanconi anaemia nuclear complex GO:0043240 8.8 FANCA FANCC FANCG

Biological processes related to Pancytopenia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 DNA repair GO:0006281 9.78 FANCA FANCC FANCG MGMT
2 cell proliferation GO:0008283 9.55 CSF1 DKC1 EPO MPL THPO
3 positive regulation of Ras protein signal transduction GO:0046579 9.46 CSF1 EPO
4 telomere maintenance via telomerase GO:0007004 9.43 DKC1 TERT
5 interstrand cross-link repair GO:0036297 9.43 FANCA FANCC FANCG
6 positive regulation of nitric-oxide synthase activity GO:0051000 9.4 DHFR TERT
7 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.32 CSF1 CSF2
8 macrophage differentiation GO:0030225 9.07 CSF1
9 neutrophil differentiation GO:0030223 8.65 CSF2
10 thrombopoietin-mediated signaling pathway GO:0038163 8.62 MPL THPO

Molecular functions related to Pancytopenia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.46 CSF1 CSF2 CSF3 THPO
2 telomerase RNA binding GO:0070034 9.26 DKC1 TERT
3 telomerase activity GO:0003720 8.96 DKC1 TERT
4 growth factor activity GO:0008083 8.92 CSF1 CSF2 CSF3 THPO

Sources for Pancytopenia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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