Aliases & Classifications for Panic Disorder

MalaCards integrated aliases for Panic Disorder:

Name: Panic Disorder 12 72 36 51 40 41 14 69
Panic Anxiety Syndrome 12
Panic Disorder 1 69
Panic 51

Classifications:



External Ids:

Disease Ontology 12 DOID:594
MeSH 41 D016584
NCIt 46 C34890
KEGG 36 H01664
ICD10 32 F41.0

Summaries for Panic Disorder

MedlinePlus : 40 Panic disorder is a type of anxiety disorder. It causes panic attacks, which are sudden feelings of terror when there is no real danger. You may feel as if you are losing control. You may also have physical symptoms, such as Fast heartbeat Chest or stomach pain Breathing difficulty Weakness or dizziness Sweating Feeling hot or a cold chill Tingly or numb hands Panic attacks can happen anytime, anywhere, and without warning. You may live in fear of another attack and may avoid places where you have had an attack. For some people, fear takes over their lives and they cannot leave their homes. Panic disorder is more common in women than men. It usually starts when people are young adults. Sometimes it starts when a person is under a lot of stress. Most people get better with treatment. Therapy can show you how to recognize and change your thinking patterns before they lead to panic. Medicines can also help. NIH: National Institute of Mental Health

MalaCards based summary : Panic Disorder, also known as panic anxiety syndrome, is related to panic disorder 1 and agoraphobia. An important gene associated with Panic Disorder is PAND1 (Panic Disorder 1), and among its related pathways/superpathways are Peptide ligand-binding receptors and Neuroscience. The drugs Ethanol and Norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and cortex, and related phenotypes are Decreased viability and Decreased viability

Disease Ontology : 12 An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress.

Wikipedia : 72 Panic disorder is an anxiety disorder characterized by recurrent unexpected panic attacks. Panic attacks... more...

Related Diseases for Panic Disorder

Diseases in the Panic Disorder family:

Panic Disorder 1 Panic Disorder 2
Panic Disorder 3

Diseases related to Panic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 148)
# Related Disease Score Top Affiliating Genes
1 panic disorder 1 34.6 COMT PAND1
2 agoraphobia 31.6 CCKBR HTR1A MAOA PTK7 SLC6A2 SLC6A4
3 social phobia 31.1 CCK HTR3A MAOA SLC6A4
4 alexithymia 31.0 COMT HTR1A SLC6A4
5 phobia, specific 30.6 COMT MAOA
6 anxiety 30.3 CCK CCKBR COMT CRH HTR1A HTR2A
7 dysthymic disorder 30.3 HTR2A MAOA SLC6A4
8 post-traumatic stress disorder 30.2 COMT CRH HTR2A MAOA SLC6A4
9 personality disorder 30.1 COMT HTR1A HTR2A MAOA SLC6A4 TPH1
10 bipolar i disorder 30.1 COMT HTR1A HTR2A SLC6A4
11 generalized anxiety disorder 30.0 HTR1A HTR2A HTR3A MAOA SLC6A2 SLC6A4
12 phobic disorder 30.0 COMT HTR1A MAOA PTK7 SLC6A4
13 irritable bowel syndrome 30.0 CCK CRH HTR3A SLC6A4 TPH1
14 cocaine abuse 30.0 HTR3A SLC6A2 SLC6A4
15 premature ejaculation 29.9 COMT HTR1A HTR3A SLC6A4
16 obsessive-compulsive disorder 29.9 COMT HTR1A HTR2A HTR3A MAOA SLC6A4
17 eating disorder 29.8 CCK COMT POMC SLC6A4
18 tobacco addiction 29.8 COMT HTR2A MAOA TPH1
19 substance dependence 29.7 MAOA POMC SLC6A4
20 withdrawal disorder 29.6 CRH POMC TSPO
21 conduct disorder 29.6 ADORA2A COMT MAOA SLC6A4 TPH1
22 migraine with or without aura 1 29.5 COMT HTR1A HTR2A HTR3A MAOA SLC6A4
23 borderline personality disorder 29.3 COMT HTR1A HTR2A MAOA SLC6A4 TPH1
24 attention deficit-hyperactivity disorder 29.0 COMT HTR1A HTR2A MAOA SLC6A2 SLC6A4
25 bipolar disorder 28.9 COMT CRH HTR1A HTR2A HTR3A MAOA
26 major depressive disorder 28.8 COMT CRH HTR1A HTR2A HTR3A MAOA
27 disease of mental health 28.6 CCK COMT CRH HTR1A HTR2A MAOA
28 schizophrenia 28.4 ADORA2A CCK CCKAR COMT HTR1A HTR2A
29 mood disorder 28.4 COMT CRH HTR1A HTR2A MAOA POMC
30 alcohol dependence 28.0 CCK COMT HTR1A HTR2A HTR3A MAOA
31 panic disorder 3 12.3
32 panic disorder 2 12.1
33 alzheimer disease 5 10.6 HTR2A SLC6A4
34 schizophrenia 5 10.6 HTR1A HTR2A
35 schizoid personality disorder 10.5 HTR1A HTR2A
36 hypoactive sexual desire disorder 10.5 HTR1A HTR2A
37 kleptomania 10.5 HTR1A MAOA SLC6A4
38 substance-induced psychosis 10.5 HTR1A HTR2A
39 antisocial personality disorder 10.5 COMT MAOA SLC6A4
40 pathological gambling 10.5 HTR2A MAOA SLC6A4
41 atypical depressive disorder 10.5 CRH MAOA SLC6A4
42 psychosexual disorder 10.5 HTR1A HTR2A SLC6A4
43 biliary dyskinesia 10.5 CCK TSPO
44 substance abuse 10.5 COMT MAOA SLC6A4
45 periodic limb movement disorder 10.5 HTR1A HTR2A SLC6A4
46 schizoaffective disorder 10.4 COMT HTR2A SLC6A4
47 rumination disorder 10.4 HTR1A HTR3A
48 constipation 10.4 CCK HTR3A SLC6A4
49 tardive dyskinesia 10.4 COMT HTR2A
50 opioid addiction 10.4 CCK CCKAR CCKBR COMT

Graphical network of the top 20 diseases related to Panic Disorder:



Diseases related to Panic Disorder

Symptoms & Phenotypes for Panic Disorder

GenomeRNAi Phenotypes related to Panic Disorder according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00381-A-1 9.1 HTR1A HTR3A SLC6A4
2 Decreased viability GR00381-A-3 9.1 HTR1A HTR3A SLC6A4

MGI Mouse Phenotypes related to Panic Disorder:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.36 MAOA COMT ADORA2A CRH CCK CCKAR
2 cardiovascular system MP:0005385 10.21 COMT ADORA2A HTR1A CCKBR TSPO SLC6A2
3 homeostasis/metabolism MP:0005376 10.2 COMT ADORA2A CRH CCK CCKAR HTR1A
4 growth/size/body region MP:0005378 10.15 HTR3A CCKBR ADORA2A CRH CCKAR PTK7
5 endocrine/exocrine gland MP:0005379 10.1 COMT CRH CCK CCKAR HTR2A HTR3A
6 nervous system MP:0003631 10 COMT ADORA2A CRH CCK CCKAR HTR1A
7 integument MP:0010771 9.91 ADORA2A CRH HTR3A CCKBR SLC6A2 SLC6A4
8 renal/urinary system MP:0005367 9.56 COMT CRH CCK CCKAR HTR3A CCKBR
9 respiratory system MP:0005388 9.17 COMT ADORA2A CRH CCKAR PTK7 TPH1

Drugs & Therapeutics for Panic Disorder

Drugs for Panic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 162)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4,Phase 2,Phase 3 64-17-5 702
2
Norepinephrine Approved Phase 4,Phase 3 51-41-2 439260
3
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
4
Citalopram Approved Phase 4,Phase 1 59729-33-8 2771
5
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2 61869-08-7 43815
6
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
7
Clozapine Approved Phase 4 5786-21-0 2818
8
Risperidone Approved, Investigational Phase 4,Phase 3,Phase 2 106266-06-2 5073
9
Ziprasidone Approved Phase 4 146939-27-7 60854
10
Alprazolam Approved, Illicit, Investigational Phase 4,Phase 2,Phase 1 28981-97-7 2118
11
Sertraline Approved Phase 4,Phase 2,Phase 3,Phase 1 79617-96-2 68617
12
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
13
Clonazepam Approved, Illicit Phase 4,Phase 2,Phase 3 1622-61-3 2802
14
Vortioxetine Approved, Investigational Phase 4 508233-74-7 9966051
15
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
16
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
17 Quetiapine Fumarate Phase 4 111974-72-2
18
Serotonin Phase 4,Phase 3,Phase 2,Phase 1 50-67-9 5202
19 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1
20 Serotonin Agents Phase 4,Phase 3,Phase 2,Phase 1
21 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
22 Muscarinic Antagonists Phase 4,Phase 1
23 Cholinergic Agents Phase 4,Phase 1,Early Phase 1
24 GABA Agents Phase 4,Phase 2,Phase 3,Phase 1
25 Cholinergic Antagonists Phase 4,Phase 1
26 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
29 Cytochrome P-450 CYP2D6 Inhibitors Phase 4,Phase 3,Phase 2
30 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
31 Parasympatholytics Phase 4,Phase 1
32 Peripheral Nervous System Agents Phase 4,Phase 1,Early Phase 1
33 Anticonvulsants Phase 4,Phase 2,Phase 3
34 Antidepressive Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Antidepressive Agents, Second-Generation Phase 4,Phase 3,Phase 2,Phase 1
36 Antimanic Agents Phase 4
37 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Phase 1
38 Antipsychotic Agents Phase 4,Phase 3,Phase 2
39 Autonomic Agents Phase 4,Phase 1,Early Phase 1
40 Antiparkinson Agents Phase 4,Phase 1
41 Analgesics Phase 4
42 Serotonin 5-HT1 Receptor Agonists Phase 4
43 Serotonin 5-HT3 Receptor Antagonists Phase 4
44 Serotonin and Noradrenaline Reuptake Inhibitors Phase 4,Phase 3
45 Serotonin Antagonists Phase 4,Phase 3,Phase 2
46 GABA Modulators Phase 4,Phase 2,Phase 3,Phase 1
47 Dopamine Agents Phase 4,Phase 3,Phase 2
48 Anti-Anxiety Agents Phase 4,Phase 2,Phase 1
49 Dopamine Antagonists Phase 4,Phase 3,Phase 2
50 Duloxetine Hydrochloride Phase 4

Interventional clinical trials:

(show top 50) (show all 213)

# Name Status NCT ID Phase Drugs
1 Costs of Lost Productive Time Among Korean Workers With Panic Disorder and Effect of Treatment With Paroxetine Controlled Release Unknown status NCT00492414 Phase 4 Paroxetine CR
2 Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD Unknown status NCT00579280 Phase 4 quetiapine SR;divalproex sodium ER;placebo
3 The Efficacy and Tolerability of Duloxetine for the Treatment of Panic Disorder Completed NCT00438971 Phase 4 Duloxetine
4 A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients Completed NCT00619892 Phase 4 quetiapine XR;placebo
5 A Study Of Sertraline Compared With Paroxetine In The Treatment Of Panic Disorder Completed NCT00677352 Phase 4 sertraline;Paroxetine
6 Paroxetine vs Placebo Combined With Aerobic Exercise or Relaxation in Panic Disorder Completed NCT00540098 Phase 4 paroxetine + aerobic exercise;Paroxetine + relaxation;Placebo + aerobic exercise;Placebo + relaxation
7 Escitalopram Trial for Irritable Bowel Syndrome (IBS) Patients With Panic Disorder Completed NCT01551225 Phase 4 Escitalopram
8 Changes of Cerebral Glucose Metabolism After 12 Weeks of Paroxetine Treatment in Panic Disorder Completed NCT00767754 Phase 4 Paxil CR
9 Changes of Cerebral Glucose Metabolism and After 12 Weeks of Escitalpram Treatment in Panic Disorder Completed NCT00767871 Phase 4 Lexapro
10 A 10-Week, Open-Label, Flexible Dose Adaptive Study Evaluating the Efficacy of Vortioxetine in Subjects With Panic Disorder Completed NCT02395510 Phase 4 Vortioxetine
11 Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine Completed NCT02852577 Phase 4 Clonazepam;Paroxetine
12 Efficacy of Aerobic Exercise Added to Alprazolam in Panic Disorder Treatment Completed NCT00803400 Phase 4 Alprazolam;Alprazolam + Aerobic exercise
13 Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression Completed NCT00031317 Phase 4 Paroxetine;Clozapine
14 Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravamâ„¢ and an SSRI or SNRI to Treatment With an SSRI or SNRI Alone in Subjects With Generalized Anxiety Disorder or Panic Disorder Completed NCT00266409 Phase 4 Niravam;SSRI/SNRI
15 A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients Completed NCT00198094 Phase 4 Sertraline and Alprazolam XR
16 A Study of Risperidone Monotherapy in Bipolar Anxiety Completed NCT00167479 Phase 4 risperidone (Risperdal)
17 Aripiprazole for the Treatment of Refractory Anxiety Completed NCT00438386 Phase 4 Aripiprazole
18 Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD) Completed NCT01172652 Phase 4 Ziprasidone;Placebo
19 The Effects of Treatment With Sertraline for Noncardiac Chest Pain Completed NCT01114100 Phase 4 sertraline;placebo
20 A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients Completed NCT01201967 Phase 4
21 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4 Psychotropic medication optimization
22 A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI's, and SNRI's Treatment in Major Depression With Anxiety Completed NCT00229645 Phase 4 Quetiapine Fumarate (Seroquel®)
23 Paroxetine - Controlled Release in the Treatment of Irritable Bowel Syndrome (IBS) Completed NCT00610909 Phase 4 Paroxetine CR;Placebo
24 Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety Completed NCT00352469 Phase 4 Seroquel XR
25 Non Cardiac Chest Pain and Benign Palpitations Completed NCT00623454 Phase 4
26 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4 Sertraline
27 Ketamine Infusion for Adolescent Depression and Anxiety Recruiting NCT02579928 Phase 4 Ketamine;Midazolam
28 Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders Active, not recruiting NCT00182533 Phase 4 Sertraline;Placebo
29 A Study to Evaluate the Use of Extended Release Alprazolam in the Treatment of Adolescents With Panic Disorder Terminated NCT00635531 Phase 4 alprazolam XR
30 A Study to Assess the Long-Term Use of Alprazolam Extended Release (XL) in the Treatment of Adolescents With Panic Disorder Terminated NCT00635076 Phase 4 alprazolam XR
31 A Study To Assess the Safety of Extended Release Alprazolam for the Treatment of Adolescents With Panic Disorder or Anxiety With Panic Attacks Terminated NCT00634790 Phase 4 alprazolam XR
32 D-cycloserine Augmented CBT for Panic Disorder Unknown status NCT01680107 Phase 3 d-cycloserine;placebo
33 Mechanisms of Panic Disorders Treatment Unknown status NCT01323556 Phase 2, Phase 3
34 Study Comparing Venlafaxine vs. Paroxetine in Panic Disorder Completed NCT00195598 Phase 3 VENLAFAXINE;Paroxetine
35 Psychodynamic Therapy for Treating Panic Disorder Completed NCT00128388 Phase 2, Phase 3
36 Internet-Versus Group-Administered Cognitive Behavior Therapy for Panic Disorder Completed NCT00845260 Phase 3
37 Therapies for Treatment-Resistant Panic Disorder Symptoms Completed NCT00118417 Phase 2, Phase 3 Clonazepam;Sertraline
38 Comparison of Psychotherapy Programs to Treat Panic Disorder Completed NCT00353470 Phase 3
39 Treatment of Panic Disorder: Long Term Strategies Completed NCT00000368 Phase 3 Paroxetine or other medication - algorithm used
40 Levetiracetam Treatment of Panic Disorder and Lactate-Induced Panic Attacks Completed NCT00279617 Phase 3 levetiracetam
41 Study Evaluating Venlafaxine ER in Patients With Panic Disorder Completed NCT00044772 Phase 3 Venlafaxine ER
42 Study Evaluating Venlafaxine ER in Adults With Panic Disorder Completed NCT00038896 Phase 3 Venlafaxine ER
43 Treatment of Social Phobia and Panic Disorder in Adults Completed NCT00619138 Phase 3
44 Virtual Reality Exposure Therapy in Agoraphobic Participants Completed NCT00734370 Phase 2, Phase 3
45 Improving Quality of Primary Care for Patients With Anxiety and/or Panic Disorders Completed NCT00102427 Phase 2, Phase 3
46 Telephone-Based Care Management Program for Individuals With Anxiety Disorders Completed NCT00158327 Phase 3
47 Online Treatments for Mood and Anxiety Disorders in Primary Care Completed NCT01482806 Phase 2, Phase 3
48 Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder Completed NCT00277654 Phase 3 Risperidone
49 Fluoxetine for Anxious Children Completed NCT00000381 Phase 3 Fluoxetine
50 Functional Outcome in Postpartum Depression in Women Treated With Desvenlafaxine Completed NCT01527786 Phase 3 Desvenlafaxine

Search NIH Clinical Center for Panic Disorder

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: panic disorder

Genetic Tests for Panic Disorder

Anatomical Context for Panic Disorder

MalaCards organs/tissues related to Panic Disorder:

38
Heart, Brain, Cortex, Amygdala, Testes, Prefrontal Cortex, Cingulate Cortex

Publications for Panic Disorder

Articles related to Panic Disorder:

(show top 50) (show all 1246)
# Title Authors Year
1
Risks and benefits of medications for panic disorder: a comparison of SSRIs and benzodiazepines. ( 29357714 )
2018
2
Changes in perceived centrality of anxious events following cognitive behavioral therapy for social anxiety disorder and panic disorder. ( 29425950 )
2018
3
Cytokine alterations in panic disorder: A systematic review. ( 29241050 )
2018
4
The effect of panic disorder versus anxiety sensitivity on event-related potentials during anticipation of threat. ( 29291580 )
2018
5
A Brief Interview to Detect Panic Attacks and Panic Disorder in Emergency Department Patients with Cardiopulmonary Complaints. ( 29320381 )
2018
6
Stress hormone response to the DEX-CRH test and its relation to psychotherapy outcome in panic disorder patients with and without agoraphobia. ( 29391399 )
2018
7
Whole-exome sequencing and gene-based rare variant association tests suggest that PLA2G4E might be a risk gene for panic disorder. ( 29391400 )
2018
8
Cue and context conditioning to respiratory threat: Effects of suffocation fear and implications for the etiology of panic disorder. ( 29330006 )
2018
9
Dismantling cognitive-behaviour therapy for panic disorder: a systematic review and component network meta-analysis. ( 29368665 )
2018
10
Does cognitive behavioral therapy alter mental defeat and cognitive flexibility in patients with panic disorder? ( 29329597 )
2018
11
The differences between patients with panic disorder and healthy controls in psychophysiological stress profile. ( 29445280 )
2018
12
Cardiorespiratory concerns shape brain responses during automatic panic-related scene processing in patients with panic disorder. ( 29252163 )
2018
13
Koro in panic disorder: Beyond a culture bound phenomena. ( 29447990 )
2018
14
Varenicline-Induced Panic Disorder in a Previously Healthy Patient. ( 29363353 )
2018
15
No significant difference in long-term remission between psychological therapies and antidepressants in panic disorder. ( 28701335 )
2017
16
What is the effect on comorbid personality disorder of brief panic-focused psychotherapy in patients with panic disorder? ( 29212135 )
2017
17
The indirect effect of panic disorder on smoking cognitions via difficulties in emotion regulation. ( 28395248 )
2017
18
Short-term efficacy of psychological and psychopharmacological interventions for panic disorder appears not to be different. ( 28673930 )
2017
19
Does patient reluctance towards exposure and psychologists' attitudes about evidence based practice influence treatment recommendations for panic disorder? An experimental investigation. ( 28325630 )
2017
20
Contribution of Group Therapeutic Factors to the Outcome of Cognitive-Behavioral Therapy for Patients with Panic Disorder. ( 28359425 )
2017
21
Executive Functions of Obsessive Compulsive Disorder and Panic Disorder Patients in Comparison to Healty Controls. ( 29321703 )
2017
22
Fear of Fear and Broad Dimensions of Psychopathology over the Course of Cognitive Behavioural Therapy for Panic Disorder with Agoraphobia in Japan. ( 29259145 )
2017
23
Modeling the development of panic disorder with interoceptive conditioning. ( 27887860 )
2017
24
Association between personality traits and Escitalopram treatment efficacy in panic disorder. ( 28472591 )
2017
25
Treating Panic Disorder Hypnotically. ( 28891770 )
2017
26
Burden and Distress in Caregivers of Patients With Panic Disorder and Agoraphobia. ( 27861457 )
2017
27
Acid-sensing T cell death associated gene-8 receptor expression in panic disorder. ( 28736033 )
2017
28
Mean Platelet Volume and Platelet Distribution Width Level in Patients with Panic Disorder. ( 28479788 )
2017
29
Association between sleep disorder and panic disorder in South Korea: Nationwide nested case-control study of data from 2004 to 2013. ( 29223044 )
2017
30
Genetic Polymorphism of 1019C/G (rs6295) Promoter of Serotonin 1A Receptor and Catechol-O-Methyltransferase in Panic Disorder. ( 28096880 )
2017
31
Cardiorespiratory concerns shape brain responses during automatic panic-related scene processing in patients with panic disorder. ( 28949287 )
2017
32
Impact of childhood trauma on course of panic disorder: contribution of clinical and personality characteristics. ( 28369890 )
2017
33
Basic Self-Disturbances beyond Schizophrenia: Discrepancies and Affinities in Panic Disorder - An Empirical Clinical Study. ( 28259879 )
2017
34
Psychoticism in patients with panic disorder with or without comorbid agoraphobia. ( 28345374 )
2017
35
Neurobiological and clinical effects of fNIRS-controlled rTMS in patients with panic disorder/agoraphobia during cognitive-behavioural therapy. ( 29085773 )
2017
36
Personality Traits in Panic Disorder Patients With and Without Comorbidities. ( 28926359 )
2017
37
Management of Treatment-Resistant Panic Disorder. ( 29238651 )
2017
38
Reduction in Costs after Treating Comorbid Panic Disorder with Agoraphobia and Generalized Anxiety Disorder. ( 28418834 )
2017
39
The implementation of guided Internet-based cognitive behaviour therapy for panic disorder in a routine-care setting: effectiveness and implementation efforts. ( 28714775 )
2017
40
Misinterpretation of the Borg's Rating of Perceived Exertion Scale by patients with panic disorder during ergospirometry challenge. ( 28761695 )
2017
41
The development and validation of static and adaptive screeners to measure the severity of panic disorder, social anxiety disorder, and obsessive compulsive disorder. ( 28370638 )
2017
42
Panic disorder and cardiovascular diseases: an overview. ( 28893114 )
2017
43
Association of Panic Disorder, Generalized Anxiety Disorder, and Benzodiazepine Treatment During Pregnancy With Risk of Adverse Birth Outcomes. ( 28903165 )
2017
44
Perceived criticism predicts outcome of psychotherapy for panic disorder: Replication and extension. ( 28045286 )
2017
45
Sudden gains in exposure-focused cognitive-behavioral group therapy for panic disorder. ( 28493541 )
2017
46
No Effects of D-Cycloserine Enhancement in Exposure With Response Prevention Therapy in Panic Disorder With Agoraphobia: A Double-Blind, Randomized Controlled Trial. ( 28820746 )
2017
47
Natriuretic Peptides in Anxiety and Panic Disorder. ( 28061968 )
2017
48
Quality of Life in Patients with Coronary Artery Disease and Panic Disorder: A Comparative Study. ( 28042398 )
2017
49
Decision-making in panic disorder. Preliminary report. ( 28953790 )
2017
50
Improvement in adult anxious and avoidant attachment during cognitive behavioral therapy for panic disorder. ( 28826378 )
2017

Variations for Panic Disorder

Expression for Panic Disorder

Search GEO for disease gene expression data for Panic Disorder.

Pathways for Panic Disorder

Pathways related to Panic Disorder according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.38 ADORA2A CCK CCKAR CCKBR CRH HTR1A
2 12.36 COMT HTR1A POMC TPH1 TPH2
3
Show member pathways
12.07 ADORA2A CCKAR CCKBR HTR2A
5 11.91 HTR1A HTR2A HTR3A MAOA SLC6A4 TPH1
6 11.74 ADORA2A CCKBR HTR2A
7
Show member pathways
11.58 COMT SLC6A2 SLC6A4
8 11.55 HTR1A HTR2A HTR3A MAOA SLC6A4 TPH1
9
Show member pathways
11.29 ADORA2A MAOA SLC6A2 SLC6A4 TPH2
10
Show member pathways
11 COMT MAOA SLC6A4
11
Show member pathways
10.89 COMT MAOA TPH1
12
Show member pathways
10.72 COMT MAOA
13 10.68 COMT MAOA
14 10.64 CCK CCKBR
15 10.61 HTR1A HTR2A HTR3A MAOA SLC6A4 TPH1
16 10.32 CRH POMC

GO Terms for Panic Disorder

Cellular components related to Panic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.56 SLC6A2 SLC6A4 TPH1 TPH2
2 integral component of plasma membrane GO:0005887 9.56 ADORA2A CCKAR CCKBR HTR1A HTR2A PTK7
3 neuronal cell body GO:0043025 9.55 ADORA2A CCK CRH HTR2A HTR3A
4 axon GO:0030424 9.02 ADORA2A CCK COMT HTR2A HTR3A

Biological processes related to Panic Disorder according to GeneCards Suite gene sharing:

(show all 29)
# Name GO ID Score Top Affiliating Genes
1 chemical synaptic transmission GO:0007268 9.91 CRH HTR2A HTR3A SLC6A2
2 circadian rhythm GO:0007623 9.79 SLC6A4 TPH1 TPH2
3 phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200 9.73 CCKAR CCKBR HTR2A
4 response to estrogen GO:0043627 9.72 COMT CRH TPH2
5 adrenal gland development GO:0030325 9.64 CRH TSPO
6 synaptic transmission, dopaminergic GO:0001963 9.64 ADORA2A CRH
7 vasoconstriction GO:0042310 9.63 HTR1A SLC6A4
8 sensory perception GO:0007600 9.63 ADORA2A CCKBR
9 behavior GO:0007610 9.61 HTR1A HTR2A
10 neurotransmitter catabolic process GO:0042135 9.6 COMT MAOA
11 catecholamine metabolic process GO:0006584 9.59 COMT MAOA
12 positive regulation of mitochondrial depolarization GO:0051901 9.58 CCK TSPO
13 regulation of behavior GO:0050795 9.58 HTR1A HTR2A
14 monoamine transport GO:0015844 9.57 SLC6A2 SLC6A4
15 aromatic amino acid family metabolic process GO:0009072 9.54 TPH1 TPH2
16 dopamine catabolic process GO:0042420 9.52 COMT MAOA
17 positive regulation of glutamate secretion GO:0014049 9.51 ADORA2A CCK
18 response to drug GO:0042493 9.5 ADORA2A COMT CRH HTR2A SLC6A2 SLC6A4
19 dopamine uptake involved in synaptic transmission GO:0051583 9.49 SLC6A2 SLC6A4
20 indolalkylamine biosynthetic process GO:0046219 9.48 TPH1 TPH2
21 serotonin receptor signaling pathway GO:0007210 9.46 HTR1A HTR2A
22 serotonin biosynthetic process GO:0042427 9.43 TPH1 TPH2
23 regulation of serotonin secretion GO:0014062 9.37 CRH HTR1A
24 regulation of hormone secretion GO:0046883 9.33 CCKAR HTR1A HTR2A
25 cholecystokinin signaling pathway GO:0038188 9.32 CCKAR CCKBR
26 response to pain GO:0048265 8.92 COMT CRH SLC6A2 TSPO
27 positive regulation of cell proliferation GO:0008284 10.02 CCK CCKBR CRH HTR1A HTR2A
28 G-protein coupled receptor signaling pathway GO:0007186 10.01 ADORA2A CCK CCKAR CCKBR CRH HTR1A
29 signal transduction GO:0007165 10 ADORA2A CCK CCKAR CCKBR CRH HTR1A

Molecular functions related to Panic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transducer activity GO:0004871 9.83 ADORA2A CCKAR CCKBR HTR1A HTR2A
2 hormone activity GO:0005179 9.63 CCK CRH POMC
3 neuropeptide hormone activity GO:0005184 9.43 CCK CRH POMC
4 monoamine transmembrane transporter activity GO:0008504 9.4 SLC6A2 SLC6A4
5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 9.37 TPH1 TPH2
6 dopamine:sodium symporter activity GO:0005330 9.32 SLC6A2 SLC6A4
7 tryptophan 5-monooxygenase activity GO:0004510 9.16 TPH1 TPH2
8 cholecystokinin receptor activity GO:0004951 8.96 CCKAR CCKBR
9 serotonin binding GO:0051378 8.8 HTR1A HTR2A HTR3A

Sources for Panic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....