MCID: PNN001
MIFTS: 46

Panniculitis malady

Muscle diseases, Skin diseases categories
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Summaries for Panniculitis

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65Wikipedia, 33MalaCards
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Wikipedia:65 Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the... more...

MalaCards: Panniculitis is related to pancreatitis and alopecia. An important gene associated with Panniculitis is TIA1 (TIA1 cytotoxic granule-associated RNA binding protein), and among its related pathways is Lymphocyte Signaling. The compounds [alcl] and neopterin have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and pancreas, and related mouse phenotypes are cellular and mortality/aging.

Aliases & Classifications for Panniculitis

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 58SNOMED-CT, 27ICD9CM, 35MeSH, 25ICD10
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Related Diseases for Panniculitis

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17GeneCards, 18GeneDecks
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Diseases related to Panniculitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 231)
idRelated DiseaseScoreTop Affiliating Genes
1pancreatitis31.1SLC17A5, SERPINA1
2alopecia30.4AIRE
3acute pancreatitis30.3SERPINA1, SLC17A5
4hepatitis30.2SERPINA1, GZMB, SLC17A5
5leukemia30.1TIA1, NCAM1, GZMB
6b-cell lymphomas30.1GZMB, TIA1
7hemophagocytic lymphohistiocytosis30.1GZMB, NCAM1
8melanoma30.1GZMB, SERPINA1, TIA1
9myopathy29.9SLC17A5, NCAM1
10cutaneous t cell lymphoma29.8TIA1, GZMB
11autoimmune hepatitis29.8AIRE, SLC17A5
12hepatitis c29.8SLC17A5, SERPINA1
13polymyositis29.7GZMB, NCAM1
14primary biliary cirrhosis29.7SLC17A5, GZMB, AIRE
15hepatitis b29.7SERPINA1, GZMB, SLC17A5
16myositis29.7SLC17A5, GZMB, NCAM1
17subcutaneous panniculitis-like t-cell lymphoma10.9
18lupus erythematosus10.7
19cytophagic histiocytic panniculitis10.7
20nodular nonsuppurative panniculitis10.7
21lupus erythematosus panniculitis10.6
22dermatomyositis10.4
23systemic lupus erythematosus10.3
24dermatitis10.3
25fasciitis10.3
26lipodermatosclerosis10.3
27arthritis10.3
28multiple sclerosis10.3
29rheumatoid arthritis10.2
30acinar cell carcinoma10.2
31alpha 1-antitrypsin deficiency10.2
32adenocarcinoma10.2
33vasculitis10.2
34lipodystrophy10.2
35scleroderma10.2
36discoid lupus erythematosus10.2
37glomerulonephritis10.1
38galactosemia10.1SERPINA1
39cutaneous lupus erythematosus10.1
40calciphylaxis10.1
41histiocytosis10.1
42histoplasmosis10.1
43hypertrichosis10.1
44peritonitis10.1
45myelodysplastic syndromes10.1
46infantile onset panniculitis with uveitis and systemic granulomatosis10.1
47lymphomatoid papulosis10.1TIA1, GZMB
48reticulosarcoma10.1GZMB, TIA1
49mycosis fungoides10.1TIA1, GZMB
50alopecia areata10.0GZMB, AIRE

Graphical network of the top 20 diseases related to Panniculitis:



Diseases related to panniculitis

Symptoms for Panniculitis

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Drugs & Therapeutics for Panniculitis

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Panniculitis

Search NIH Clinical Center for Panniculitis

Genetic Tests for Panniculitis

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Anatomical Context for Panniculitis

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33MalaCards
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MalaCards organs/tissues related to Panniculitis:

33
T cells, Skin, Pancreas, Breast, Liver, B cells, Kidney, Colon, Thyroid, Bone marrow, Bone, Myeloid, Nk cells, Lung, Brain, Prostate, Cervix

Animal Models for Panniculitis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Panniculitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053848.1SLC17A5, GZMB, NCAM1, AIRE
2MP:00107687.3SLC17A5, GZMB, NCAM1, TIA1, AIRE

Publications for Panniculitis

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52PubMed
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Articles related to Panniculitis:

(show top 50)    (show all 637)
idTitleAuthorsYear
1
Mesenteric panniculitis in a patient with ankylosing spondylitis. (23523461)
2013
2
Pediatric subcutaneous panniculitis-like T-cell lymphoma with features of hemophagocytic syndrome. (23868752)
2013
3
Images in clinical medicine. Lobular panniculitis. (23363500)
2013
4
Post-steroid panniculitis: A rare case report. (24350016)
2013
5
Adding pancreatic panniculitis to the panel of skin lesions associated with triple therapy of chronic hepatitis C. (23410147)
2013
6
Mesenteric panniculitis patients requiring emergency surgery: report of three cases. (22706750)
2012
7
Outcome study of the surgical management of panniculitis. (21629099)
2012
8
Pancreatic panniculitis. (22158400)
2012
9
Subcutaneous panniculitis-like T-cell lymphoma: successful treatment with systemic steroid alone. (22032642)
2012
10
Antiphospholipid-antibody-associated panniculitis. (23286808)
2012
11
Subcutaneous panniculitis-like T-cell lymphoma: a clinical and pathologic study of 14 korean patients. (21909203)
2011
12
Positron-emission tomography findings indicating the involvement of the whole body skin in subcutaneous panniculitis-like T cell lymphoma. (20972680)
2011
13
Multimodality imaging of subcutaneous panniculitis-like T-cell lymphoma. (21628950)
2011
14
Polyarthritis with chondronecrosis associated with osteonecrosis, panniculitis and pancreatitis. (19575201)
2010
15
Panniculitis ossificans non-traumatica of the scalp. (19615016)
2010
16
Inguinal panniculitis in a young Tasmanian devil (Sarcophilus harrisii) caused by Mycobacterium mageritense. (20529031)
2010
17
A case with an indolent course of subcutaneous panniculitis-like T-cell lymphoma demonstrating Epstein-Barr virus positivity and simulating dermatitis artefacta. (20141236)
2010
18
Intramedullary fat necrosis, polyarthritis and panniculitis with pancreatic tumor: a case report. (21199459)
2010
19
Anakinra for difficult-to-treat neutrophilic panniculitis: IL-1 blockade as a promising treatment option for neutrophil-mediated inflammatory skin disease. (20197651)
2010
20
Kimura's disease with eosinophilic panniculitis--treated with cyclosporine: a case report. (20236545)
2010
21
Mixed-cell granulomatous panniculitis on the cheek due to injection of solution containing phosphatidylcholine and deoxycholate. (20979342)
2010
22
Panniculitis associated with steroid use. (20427888)
2010
23
Panniculitis in a patient presenting with a pancreatic tumour and polyarthritis: a case report. (19830189)
2009
24
New Findings in PiZZ alpha1-antitrypsin deficiency-related panniculitis. Demonstration of skin polymers and high dosing requirements of intravenous augmentation therapy. (19218787)
2009
25
Aggressive subcutaneous panniculitis-like T-cell lymphoma with hemophagocytosis in two children (subcutaneous panniculitis-like T-cell lymphoma). (19744747)
2009
26
Alfa-1-antitrypsin deficiency panniculitis acquired after liver transplant and successfully treated with retransplant. (19293031)
2009
27
Bartonella-associated meningoradiculoneuritis and dermatitis or panniculitis in 3 dogs. (18466250)
2008
28
Fungal panniculitis in renal transplant recipients. (18086276)
2008
29
alpha1-Antitrypsin deficiency presenting with panniculitis and incidental discovery of chronic obstructive pulmonary disease. (17910720)
2007
30
Cytophagic histiocytic panniculitis with fatal haemophagocytic lymphohistiocytosis in a paediatric patient with perforin gene mutation. (17601962)
2007
31
Subcutaneous panniculitis-like T-cell lymphoma presenting with hemophagocytic lymphohistiocytosis and skin lesions with characteristic high-resolution ultrasonographic findings. (16465478)
2007
32
Dermatomyositis, lobar panniculitis and inflammatory myopathy with abundant macrophages. (16809038)
2006
33
Intraductal papillary mucinous adenoma of the pancreas presenting with lobular panniculitis. (16273371)
2006
34
Panniculitis, polyarthritis and osteomyelitis associated with pancreatic neoplasia in two dogs. (16842278)
2006
35
Subcutaneous panniculitis lymphoma: erythema nodosum-like. (17229342)
2006
36
Systemic treatment of sterile panniculitis with tacrolimus and prednisolone in dogs. (16462127)
2006
37
Fibrotic involution of sural muscles secondary to lupus panniculitis. (15895908)
2005
38
Lupus panniculitis involving the parotid/periparotid regions and breast; a rare presentation. (15762074)
2004
39
Small vessel vasculitis and relapsing panniculitis in tumour necrosis factor receptor associated periodic syndrome (TRAPS). (15479908)
2004
40
Coexistence of acquired localized hypertrichosis and lipoatrophy after lupus panniculitis. (15097972)
2004
41
Cytotoxic gamma/delta subcutaneous panniculitis-like T-cell lymphoma: report of a case with pulmonary involvement unresponsive to therapy. (12705758)
2003
42
Subcutaneous lymphoid hyperplasia arising at site of ethnic scarifications and mimicking subcutaneous panniculitis-like T-cell lymphoma. (11315627)
2001
43
Aggressive subcutaneous panniculitis-like T-cell lymphoma: complete remission with fludarabine, mitoxantrone and dexamethasone. (10951154)
2000
44
Cytophagic histiocytic panniculitis and subcutaneous panniculitis-like T-cell lymphoma: report of 7 cases. (10890991)
2000
45
Membranocystic lesions in a patient with cytophagic histiocytic panniculitis associated with subcutaneous T-cell lymphoma. (9650702)
1998
46
Nodular nonsuppurative panniculitis in association with primary biliary cirrhosis and Hashimoto's thyroiditis. (8686385)
1996
47
Treatment of alpha-1-antitrypsin deficiency, massive edema, and panniculitis with alpha-1 protease inhibitor. (8849167)
1996
48
Generalized proteolysis in a young woman with Weber-Christian disease (nodular nonsuppurative panniculitis). (1215832)
1975
49
Chronic relapsing febrile nodular nonsuppurative panniculitis (Weber-Christian disease); relation to rheumatic fever and allied diseases. (14780325)
1950
50
Relapsing febrile nodular nonsuppurative panniculitis; report of case treated with penicillin. (18892290)
1948

Variations for Panniculitis

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Expression for genes affiliated with Panniculitis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Panniculitis

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Pathways for genes affiliated with Panniculitis

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50PathCards, 5Cell Signaling Technology
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Pathways related to Panniculitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.2GZMB, NCAM1

Compounds for genes affiliated with Panniculitis

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45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank, 51PharmGKB
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Compounds related to Panniculitis according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1[alcl]4510.0TIA1, GZMB
2neopterin459.7SLC17A5, GZMB
3agarose459.7SERPINA1, GZMB
4hyaluronic acid45 2410.6SLC17A5, GZMB
5gold459.4GZMB, NCAM1
6nacl459.4SLC17A5, GZMB
7prednisolone45 29 1111.4SLC17A5, GZMB, TIA1
8hematoxylin459.3SLC17A5, NCAM1
9purine45 2410.3NCAM1, SLC17A5
10valproic acid45 51 24 1112.3SLC17A5, NCAM1
11heparan sulfate45 2410.3NCAM1, GZMB
12sialic acid459.3SLC17A5, NCAM1
13tacrolimus45 51 1111.1SLC17A5, GZMB
14oxygen45 2410.0SERPINA1, GZMB, SLC17A5
15lactate458.9SLC17A5, GZMB, NCAM1
16glutamate458.8NCAM1, GZMB, SLC17A5
17creatinine458.8SERPINA1, NCAM1, SLC17A5
18alanine458.8SLC17A5, GZMB, NCAM1
19estrogen458.8GZMB, NCAM1, SERPINA1
20glucose458.8SERPINA1, GZMB, SLC17A5
21cysteine458.7GZMB, NCAM1, SERPINA1
22paraffin458.6TIA1, SERPINA1, NCAM1, GZMB
23atp45 299.5SLC17A5, GZMB, NCAM1, TIA1
24ethanol45 51 24 1111.4SLC17A5, GZMB, NCAM1, SERPINA1
25heparin45 29 24 1111.4SERPINA1, NCAM1, GZMB, SLC17A5
26nitric oxide45 24 1110.4SERPINA1, NCAM1, GZMB, SLC17A5
27lipid458.4SLC17A5, GZMB, NCAM1, SERPINA1
28serine458.1AIRE, TIA1, SERPINA1, NCAM1, GZMB
29tyrosine457.9AIRE, SERPINA1, NCAM1, GZMB, SLC17A5

GO Terms for genes affiliated with Panniculitis

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16Gene Ontology
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Molecular functions related to Panniculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428028.6NCAM1, SERPINA1, AIRE

Products for genes affiliated with Panniculitis

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Sources for Panniculitis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet