MCID: PPL018
MIFTS: 47

Papillary Adenocarcinoma malady

Cancer diseases category

Summaries for Papillary Adenocarcinoma

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9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, which form complex papillary structures and exhibit compressive, destructive growth that replaces the normal tissue.

MalaCards: Papillary Adenocarcinoma, also known as infiltrating and papillary adenocarcinoma, is related to adenocarcinoma and adenoma. An important gene associated with Papillary Adenocarcinoma is FGF3 (fibroblast growth factor 3), and among its related pathways is Translational Control. The compounds bamhi and trypsinogen have been mentioned in the context of this disorder. Affiliated tissues include thyroid, lung and cervix, and related mouse phenotypes are tumorigenesis and behavior/neurological.

Wikipedia:66 Papillary adenocarcinoma is a histological form of lung cancer that is diagnosed when the malignant... more...

Aliases & Classifications for Papillary Adenocarcinoma

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9Disease Ontology, 46Novoseek, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

papillary adenocarcinoma 9 63
infiltrating and papillary adenocarcinoma 9
infiltrating papillary adenocarcinoma 9
papillary adenocarcinoma nos 9
adenocarcinoma papillary 46


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Disease Ontology9 DOID:3112
NCIt41 C2853
MeSH36 D000231

Related Diseases for Papillary Adenocarcinoma

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18GeneCards, 19GeneDecks
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Diseases related to Papillary Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma31.7NME1, NKX2-1, SCT, F2RL1
2adenoma30.4FGF3, NME1, NKX2-1, SCT, F2RL1
3pancreatitis30.2SCT, F2RL1
4hyperparathyroidism30.1SCT, FGF3
5melanoma29.9FGF3, NME1, NKX2-1, F2RL1
6thyroiditis10.9
7aggressive digital papillary adenocarcinoma10.8
8nasopharyngitis10.5
9prostatitis10.4
10fallopian tube papillary adenocarcinoma10.3
11eccrine papillary adenocarcinoma10.3
12gastric papillary adenocarcinoma10.3
13papillary adenoma10.3
14hepatitis10.3
15peritoneal serous papillary adenocarcinoma10.3
16lung papillary adenocarcinoma10.3
17hyperthyroidism10.3
18peritonitis10.3
19papillary thymic adenocarcinoma10.2
20duodenitis10.2
21hypercalcemia10.2
22adenocarcinoma in situ10.2
23cervicitis10.2
24cystadenocarcinoma10.2
25malignant mesothelioma10.2
26papilloma10.2
27pituitary adenoma10.2
28vaginitis10.2
29pheochromocytoma10.2
30follicular thyroid carcinoma10.0NKX2-1, NME1
31adenosquamous carcinoma10.0NKX2-1, NME1
32follicular adenoma10.0NKX2-1, NME1
33papillary carcinoma10.0NKX2-1, NME1
34thyroid cancer10.0NKX2-1, NME1
35neuroendocrine tumor10.0NKX2-1, SCT
36hepatitis c10.0
37intraductal papilloma10.0
38papillary serous adenocarcinoma10.0
39urethritis10.0
40myoblastoma10.0
41acromegaly10.0
42urethral diverticulum10.0
43mucinous adenocarcinoma10.0
44cholelithiasis10.0
45obstructive jaundice10.0
46papillary cystadenocarcinoma10.0
47choroiditis10.0
48renal agenesis10.0
49clear cell adenocarcinoma10.0
50papillary renal cell carcinoma10.0

Graphical network of the top 20 diseases related to Papillary Adenocarcinoma:



Diseases related to papillary adenocarcinoma

Symptoms for Papillary Adenocarcinoma

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Drugs & Therapeutics for Papillary Adenocarcinoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Papillary Adenocarcinoma

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Anatomical Context for Papillary Adenocarcinoma

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34MalaCards
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MalaCards organs/tissues related to Papillary Adenocarcinoma:

34
Thyroid, Lung, Cervix, Ovary, Lymph node, Pancreas, Prostate, Testis, Salivary gland, Kidney, Colon, Brain, Breast, Bone, Pituitary, Thymus, Testes, Uterus, Tongue, Appendix

Animal Models for Papillary Adenocarcinoma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Papillary Adenocarcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4NME1, NKX2-1, F2RL1
2MP:00053868.2FGF3, NKX2-1, SCT, F2RL1
3MP:00036317.7FGF3, NME1, NKX2-1, SCT, F2RL1
4MP:00107687.6F2RL1, NKX2-1, NME1, KEAP1, FGF3
5MP:00053767.5F2RL1, SCT, NKX2-1, NME1, KEAP1

Publications for Papillary Adenocarcinoma

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53PubMed
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Articles related to Papillary Adenocarcinoma:

(show top 50)    (show all 298)
idTitleAuthorsYear
1
Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma. (24274672)
2013
2
Duodenal adenocarcinoma with neuroendocrine features in a patient with acromegaly and thyroid papillary adenocarcinoma: a unique combination of endocrine neoplasia. (22673565)
2012
3
Salivary transcriptomic biomarkers for detection of ovarian cancer: for serous papillary adenocarcinoma. (22095100)
2012
4
Papillary adenocarcinoma arising in a tubular duplication of the jejunum. (20197430)
2010
5
Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: report of two cases. (20398195)
2010
6
Thyroid-like papillary adenocarcinoma of the nasopharynx: a case report in a 19-year-old male. (20727493)
2010
7
Villoglandular papillary adenocarcinoma of the uterine cervix: a case report and literature review. (19480259)
2009
8
Aggressive digital papillary adenocarcinoma on the palm with pulmonary metastases. (18705837)
2008
9
Papillary adenocarcinoma arising in a duplication of the cecum. (17912582)
2008
10
Unknown primary site of serous papillary adenocarcinoma involving inguinal, iliac and obturator lymph nodes co-existing with endometrial adenocarcinoma. (17701821)
2007
11
Villoglandular papillary adenocarcinoma of the uterine cervix in a pregnant woman: a case report and review of literature. (15109129)
2004
12
A case of villoglandular papillary adenocarcinoma of the cervix with lymph node metastasis. (12798484)
2003
13
Invasive papillary adenocarcinoma of the colon: is it really a distinct subtype? (12514795)
2002
14
Villoglandular papillary adenocarcinoma of the uterine cervix with bulky lymph node metastases. (12381485)
2002
15
Invasive carcinoma of the pancreas derived from intraductal papillary adenocarcinoma without mucin hypersecretion but with changes in the pancreatic duct on pancreatography. (12541053)
2002
16
Accumulation of Tc-99m HMDP in ovarian serous papillary adenocarcinoma reflecting ongoing calcification. (11564940)
2001
17
Hyperthyroidism in a patient with TSH-producing pituitary adenoma coexisting with thyroid papillary adenocarcinoma. (11228048)
2000
18
Aggressive digital papillary adenocarcinoma of the foot: the clinicopathologic features of two cases. (11131478)
2000
19
Villoglandular papillary adenocarcinoma of the uterine cervix. (10471150)
1999
20
Ewing's tumor and papillary adenocarcinoma of the thyroid in a 14-year-old girl. (9544174)
1998
21
Primary non-mucinous, non-papillary adenocarcinoma of the ureter. (9696329)
1998
22
Hypercalcemia caused by ectopic production of parathyroid hormone in a patient with papillary adenocarcinoma of the thyroid gland. (9709927)
1998
23
Expression of CD44V6 and nm23-H1 in thyroid papillary adenocarcinoma and lymph node metastasis]. (10681781)
1998
24
Intraductal papillary adenocarcinoma with mucin hypersecretion and coexistent invasive ductal carcinoma of the pancreas with apparent topographic separation. (9027658)
1996
25
Papillary adenocarcinoma of the common bile duct. (18612477)
1995
26
Papillary adenocarcinoma of the rete testis: a case report and review of the literature. (7941203)
1994
27
Intraductal mucin-hypersecreting papillary adenocarcinoma of the pancreas: a case report. (7850686)
1994
28
Papillary adenocarcinoma arising within a pedunculated cystic duct polyp. (8338103)
1993
29
Multifocal intraductal papillary adenocarcinoma of the pancreas: report of a case. (8391885)
1993
30
Papillary adenocarcinoma in thyroid hemiagenesis. (1517082)
1992
31
Alpha-fetoprotein-producing papillary adenocarcinoma originating from a uterine body. A case report. (1714227)
1991
32
Serous papillary adenocarcinoma of the endometrium. Analysis of proto-oncogene amplification, flow cytometry, estrogen and progesterone receptors, and immunohistochemistry. (1690076)
1990
33
Papillary adenocarcinoma of the rete testis: sonographic findings. (3554934)
1987
34
Diffuse intraductal papillary adenocarcinoma of the pancreas. (3827359)
1987
35
Low-grade papillary adenocarcinoma of palatal salivary gland origin. (6731663)
1984
36
Papillary adenocarcinoma of minor salivary gland origin in a child. (6639458)
1983
37
Pathologic quiz case 1: papillary adenocarcinoma in a thyroglossal duct cyst. (7138374)
1982
38
Radionuclide salivary scan imaging of a "functioning" malignant parotid tumor (mucous-producing papillary adenocarcinoma). (7077733)
1982
39
Papillary adenocarcinoma of the prostatic urethra with clear-cell appearance. (7306922)
1981
40
Papillary adenocarcinoma in ectopic thyroid. (6784077)
1981
41
Light and electron microscopic analysis of intranuclear inclusions in papillary adenocarcinoma of the lung. (6945017)
1981
42
Pseudo-Meigs syndrome with resulting papillary adenocarcinomas of the ovary and fallopian tube. (6109647)
1980
43
Papillary adenocarcinoma of prostate. (184573)
1976
44
Papillary adenocarcinoma arising in a thyroglossal duct cyst. Case report and literature review. (5701322)
1968
45
Papillary adenocarcinoma in a thyroglossal cyst. Case report and review of the literature. (5939053)
1966
46
Papillary adenocarcinoma arising in a thyroglossal duct cyst. Report of a case. (13867693)
1961
47
Papillary adenocarcinoma of the female urethra. A case report. (13775927)
1960
48
Primary papillary adenocarcinoma of the fundus of the gallbladder. (18110755)
1949
49
Resection of the common hepatic duct for papillary adenocarcinoma. (20289160)
1947
50
Mixed squamous cell carcinoma and papillary adenocarcinoma (adenocanthoma) of the thyroid gland. (20264122)
1947

Variations for Papillary Adenocarcinoma

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Expression for genes affiliated with Papillary Adenocarcinoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Papillary Adenocarcinoma

Search GEO for disease gene expression data for Papillary Adenocarcinoma.

Pathways for genes affiliated with Papillary Adenocarcinoma

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51PathCards, 5Cell Signaling Technology
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Pathways related to Papillary Adenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4KEAP1, NME1

Compounds for genes affiliated with Papillary Adenocarcinoma

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46Novoseek, 30IUPHAR, 25HMDB, 12DrugBank, 62Tocris Bioscience, 52PharmGKB
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Compounds related to Papillary Adenocarcinoma according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1bamhi469.9FGF3, NME1
2trypsinogen469.4F2RL1, SCT
3ranitidine46 30 25 1212.4SCT, F2RL1
4amiloride46 30 1211.2F2RL1, SCT
5biotin46 25 1211.2SCT, NME1
6octreotide46 62 30 1212.2SCT, F2RL1
7steroid469.2NKX2-1, NME1, FGF3
8paraffin469.0F2RL1, NKX2-1, NME1
9forskolin46 52 1210.9NKX2-1, SCT, F2RL1
10retinoic acid46 259.9NME1, NKX2-1, SCT
11sodium46 259.8NKX2-1, SCT, F2RL1
12hydrogen46 259.8KEAP1, SCT, F2RL1
13pge2468.8F2RL1, SCT, NME1
14lysine468.8KEAP1, SCT, F2RL1
15thymidine46 259.8F2RL1, SCT, NME1
16dexamethasone46 52 30 1211.7NME1, NKX2-1, F2RL1
17carbachol46 30 1210.7SCT, F2RL1
18vegf468.7FGF3, NME1, F2RL1
19cysteine468.3KEAP1, NME1, SCT, F2RL1
20serine468.3NME1, NKX2-1, SCT, F2RL1
21tyrosine468.2NME1, NKX2-1, SCT, F2RL1
22oligonucleotide468.0FGF3, NME1, NKX2-1, SCT, F2RL1

GO Terms for genes affiliated with Papillary Adenocarcinoma

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17Gene Ontology
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Biological processes related to Papillary Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hippocampus developmentGO:0217669.5NME1, NKX2-1

Products for genes affiliated with Papillary Adenocarcinoma

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Sources for Papillary Adenocarcinoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet