MCID: PPL018
MIFTS: 48

Papillary Adenocarcinoma malady

Cancer diseases category
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Summaries for Papillary Adenocarcinoma

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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, which form complex papillary structures and exhibit compressive, destructive growth that replaces the normal tissue.

MalaCards based summary: Papillary Adenocarcinoma, also known as infiltrating and papillary adenocarcinoma, is related to adenocarcinoma and pancreatitis. An important gene associated with Papillary Adenocarcinoma is FGF3 (fibroblast growth factor 3), and among its related pathways is Translational Control. The compounds bamhi and trypsinogen have been mentioned in the context of this disorder. Affiliated tissues include thyroid, lung and cervix, and related mouse phenotypes are tumorigenesis and behavior/neurological.

Wikipedia:65 Papillary adenocarcinoma is a histological form of lung cancer that is diagnosed when the malignant... more...

Aliases & Classifications for Papillary Adenocarcinoma

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Sources:
8Disease Ontology, 62UMLS, 44Novoseek, 34MeSH, 39NCIt, 57SNOMED-CT
See all sources

Papillary Adenocarcinoma, Aliases & Descriptions:

Name: Papillary Adenocarcinoma 8 62
Infiltrating and Papillary Adenocarcinoma 8
Infiltrating Papillary Adenocarcinoma 8
 
Papillary Adenocarcinoma Nos 8
Adenocarcinoma Papillary 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:3112
MeSH34 D000231
NCIt39 C2853

Related Diseases for Papillary Adenocarcinoma

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Diseases related to Papillary Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma31.3NME1, NKX2-1, SCT, F2RL1
2pancreatitis30.3SCT, F2RL1
3hyperparathyroidism30.3SCT, FGF3
4adenoma29.7FGF3, NME1, NKX2-1, SCT, F2RL1
5melanoma29.5FGF3, NME1, NKX2-1, F2RL1
6thyroiditis10.9
7aggressive digital papillary adenocarcinoma10.8
8nasopharyngitis10.5
9prostatitis10.5
10fallopian tube papillary adenocarcinoma10.4
11gastric papillary adenocarcinoma10.4
12hepatitis10.3
13peritoneal serous papillary adenocarcinoma10.3
14lung papillary adenocarcinoma10.3
15eccrine papillary adenocarcinoma10.3
16papillary adenoma10.3
17peritonitis10.3
18adenocarcinoma in situ10.3
19hyperthyroidism10.3
20follicular thyroid carcinoma10.2NKX2-1, NME1
21papillary thymic adenocarcinoma10.2
22hypercalcemia10.2
23duodenitis10.2
24cervicitis10.2
25cystadenocarcinoma10.2
26malignant mesothelioma10.2
27papilloma10.2
28pituitary adenoma10.2
29vaginitis10.2
30pheochromocytoma10.2
31adenosquamous carcinoma10.2NKX2-1, NME1
32follicular adenoma10.2NKX2-1, NME1
33papillary carcinoma10.1NKX2-1, NME1
34thyroid hurthle cell carcinoma10.1NKX2-1, NME1
35neuroendocrine tumor10.1NKX2-1, SCT
36gastric cancer10.0
37hemangioma10.0
38papillary renal cell carcinoma10.0
39wilms tumor10.0
40papillary serous adenocarcinoma10.0
41acromegaly10.0
42renal agenesis10.0
43papillary extrahepatic bile duct adenocarcinoma10.0
44hepatitis c10.0
45intraductal papilloma10.0
46urethritis10.0
47obstructive jaundice10.0
48pulmonary sclerosing hemangioma10.0
49paronychia10.0
50myoblastoma10.0

Graphical network of the top 20 diseases related to Papillary Adenocarcinoma:



Diseases related to papillary adenocarcinoma

Symptoms for Papillary Adenocarcinoma

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Drugs & Therapeutics for Papillary Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Papillary Adenocarcinoma

Search NIH Clinical Center for Papillary Adenocarcinoma

Genetic Tests for Papillary Adenocarcinoma

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Anatomical Context for Papillary Adenocarcinoma

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MalaCards organs/tissues related to Papillary Adenocarcinoma:

32
Thyroid, Lung, Cervix, Ovary, Lymph node, Pancreas, Prostate, Testis, Salivary gland, Kidney, Colon, Brain, Bone, Breast, Pituitary, Thymus, Skin, Uterus, Testes, Tongue, Appendix

Animal Models for Papillary Adenocarcinoma or affiliated genes

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MGI Mouse Phenotypes related to Papillary Adenocarcinoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4NME1, NKX2-1, F2RL1
2MP:00053868.2FGF3, NKX2-1, SCT, F2RL1
3MP:00036317.7FGF3, NME1, NKX2-1, SCT, F2RL1
4MP:00107687.6F2RL1, NKX2-1, NME1, KEAP1, FGF3
5MP:00053767.5F2RL1, SCT, NKX2-1, NME1, KEAP1

Publications for Papillary Adenocarcinoma

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Articles related to Papillary Adenocarcinoma:

(show top 50)    (show all 309)
idTitleAuthorsYear
1
A rare coexistence of villoglandular papillary adenocarcinoma of the uterine cervix and brenner tumor of the ovary. (24716032)
2014
2
Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma. (24274672)
2013
3
Duodenal adenocarcinoma with neuroendocrine features in a patient with acromegaly and thyroid papillary adenocarcinoma: a unique combination of endocrine neoplasia. (22673565)
2012
4
Salivary transcriptomic biomarkers for detection of ovarian cancer: for serous papillary adenocarcinoma. (22095100)
2012
5
Papillary adenocarcinoma arising in a tubular duplication of the jejunum. (20197430)
2010
6
Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: report of two cases. (20398195)
2010
7
Thyroid-like papillary adenocarcinoma of the nasopharynx: a case report in a 19-year-old male. (20727493)
2010
8
Aggressive digital papillary adenocarcinoma on the palm with pulmonary metastases. (18705837)
2008
9
Papillary adenocarcinoma arising in a duplication of the cecum. (17912582)
2008
10
Unknown primary site of serous papillary adenocarcinoma involving inguinal, iliac and obturator lymph nodes co-existing with endometrial adenocarcinoma. (17701821)
2007
11
Villoglandular papillary adenocarcinoma of the uterine cervix in a pregnant woman: a case report and review of literature. (15109129)
2004
12
A case of villoglandular papillary adenocarcinoma of the cervix with lymph node metastasis. (12798484)
2003
13
Invasive papillary adenocarcinoma of the colon: is it really a distinct subtype? (12514795)
2002
14
Villoglandular papillary adenocarcinoma of the uterine cervix with bulky lymph node metastases. (12381485)
2002
15
Invasive carcinoma of the pancreas derived from intraductal papillary adenocarcinoma without mucin hypersecretion but with changes in the pancreatic duct on pancreatography. (12541053)
2002
16
Accumulation of Tc-99m HMDP in ovarian serous papillary adenocarcinoma reflecting ongoing calcification. (11564940)
2001
17
Hyperthyroidism in a patient with TSH-producing pituitary adenoma coexisting with thyroid papillary adenocarcinoma. (11228048)
2000
18
Aggressive digital papillary adenocarcinoma of the foot: the clinicopathologic features of two cases. (11131478)
2000
19
Villoglandular papillary adenocarcinoma of the uterine cervix. (10471150)
1999
20
Ewing's tumor and papillary adenocarcinoma of the thyroid in a 14-year-old girl. (9544174)
1998
21
Primary non-mucinous, non-papillary adenocarcinoma of the ureter. (9696329)
1998
22
Hypercalcemia caused by ectopic production of parathyroid hormone in a patient with papillary adenocarcinoma of the thyroid gland. (9709927)
1998
23
Expression of CD44V6 and nm23-H1 in thyroid papillary adenocarcinoma and lymph node metastasis]. (10681781)
1998
24
Intraductal papillary adenocarcinoma with mucin hypersecretion and coexistent invasive ductal carcinoma of the pancreas with apparent topographic separation. (9027658)
1996
25
Papillary adenocarcinoma of the common bile duct. (18612477)
1995
26
Papillary adenocarcinoma of the rete testis: a case report and review of the literature. (7941203)
1994
27
Intraductal mucin-hypersecreting papillary adenocarcinoma of the pancreas: a case report. (7850686)
1994
28
Papillary adenocarcinoma arising within a pedunculated cystic duct polyp. (8338103)
1993
29
Multifocal intraductal papillary adenocarcinoma of the pancreas: report of a case. (8391885)
1993
30
Papillary adenocarcinoma in thyroid hemiagenesis. (1517082)
1992
31
Serous papillary adenocarcinoma of the tunica vaginalis of the testis with metastasis. (1991312)
1991
32
Alpha-fetoprotein-producing papillary adenocarcinoma originating from a uterine body. A case report. (1714227)
1991
33
Serous papillary adenocarcinoma of the endometrium. Analysis of proto-oncogene amplification, flow cytometry, estrogen and progesterone receptors, and immunohistochemistry. (1690076)
1990
34
Papillary adenocarcinoma of the rete testis: sonographic findings. (3554934)
1987
35
Diffuse intraductal papillary adenocarcinoma of the pancreas. (3827359)
1987
36
Low-grade papillary adenocarcinoma of palatal salivary gland origin. (6731663)
1984
37
Papillary adenocarcinoma of minor salivary gland origin in a child. (6639458)
1983
38
Pathologic quiz case 1: papillary adenocarcinoma in a thyroglossal duct cyst. (7138374)
1982
39
Radionuclide salivary scan imaging of a "functioning" malignant parotid tumor (mucous-producing papillary adenocarcinoma). (7077733)
1982
40
Papillary adenocarcinoma of the prostatic urethra with clear-cell appearance. (7306922)
1981
41
Papillary adenocarcinoma in ectopic thyroid. (6784077)
1981
42
Pseudo-Meigs syndrome with resulting papillary adenocarcinomas of the ovary and fallopian tube. (6109647)
1980
43
Papillary adenocarcinoma of prostate. (184573)
1976
44
Papillary adenocarcinoma arising in a thyroglossal duct cyst. Case report and literature review. (5701322)
1968
45
Papillary adenocarcinoma in a thyroglossal cyst. Case report and review of the literature. (5939053)
1966
46
Papillary adenocarcinoma arising in a thyroglossal duct cyst. Report of a case. (13867693)
1961
47
Papillary adenocarcinoma of the female urethra. A case report. (13775927)
1960
48
Primary papillary adenocarcinoma of the fundus of the gallbladder. (18110755)
1949
49
Resection of the common hepatic duct for papillary adenocarcinoma. (20289160)
1947
50
Mixed squamous cell carcinoma and papillary adenocarcinoma (adenocanthoma) of the thyroid gland. (20264122)
1947

Variations for Papillary Adenocarcinoma

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Expression for genes affiliated with Papillary Adenocarcinoma

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Expression patterns in normal tissues for genes affiliated with Papillary Adenocarcinoma

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Pathways for genes affiliated with Papillary Adenocarcinoma

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Pathways related to Papillary Adenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4KEAP1, NME1

Compounds for genes affiliated with Papillary Adenocarcinoma

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Compounds related to Papillary Adenocarcinoma according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1bamhi449.9FGF3, NME1
2trypsinogen449.4F2RL1, SCT
3ranitidine44 28 24 1112.4SCT, F2RL1
4amiloride44 28 1111.2F2RL1, SCT
5biotin44 24 1111.2SCT, NME1
6octreotide44 61 28 1112.2SCT, F2RL1
7steroid449.2NKX2-1, NME1, FGF3
8paraffin449.0F2RL1, NKX2-1, NME1
9forskolin44 50 1110.9NKX2-1, SCT, F2RL1
10retinoic acid44 249.9NME1, NKX2-1, SCT
11sodium44 249.8NKX2-1, SCT, F2RL1
12hydrogen44 249.8KEAP1, SCT, F2RL1
13pge2448.8F2RL1, SCT, NME1
14lysine448.8KEAP1, SCT, F2RL1
15thymidine44 249.8F2RL1, SCT, NME1
16dexamethasone44 50 28 1111.7NME1, NKX2-1, F2RL1
17carbachol44 28 1110.7SCT, F2RL1
18vegf448.7FGF3, NME1, F2RL1
19cysteine448.3KEAP1, NME1, SCT, F2RL1
20serine448.3NME1, NKX2-1, SCT, F2RL1
21tyrosine448.2NME1, NKX2-1, SCT, F2RL1
22oligonucleotide448.0FGF3, NME1, NKX2-1, SCT, F2RL1

GO Terms for genes affiliated with Papillary Adenocarcinoma

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Biological processes related to Papillary Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hippocampus developmentGO:0217669.5NME1, NKX2-1

Products for genes affiliated with Papillary Adenocarcinoma

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Sources for Papillary Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet