MCID: PPL019
MIFTS: 33

Papillary Conjunctivitis malady

Category: Eye diseases

Aliases & Classifications for Papillary Conjunctivitis

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Aliases & Descriptions for Papillary Conjunctivitis:

Name: Papillary Conjunctivitis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:2458
SNOMED-CT59 416878008
NCIt42 C35616
UMLS65 C0854165

Summaries for Papillary Conjunctivitis

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MalaCards based summary: Papillary Conjunctivitis is related to giant papillary conjunctivitis and blepharitis. An important gene associated with Papillary Conjunctivitis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways are CXCR3-mediated signaling events and IL4-mediated signaling events. Affiliated tissues include eye, heart and prostate, and related mouse phenotypes are hematopoietic system and immune system.

Related Diseases for Papillary Conjunctivitis

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Diseases related to Papillary Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 67)
idRelated DiseaseScoreTop Affiliating Genes
1giant papillary conjunctivitis32.5CCL11, CMA1, IL4, LTF
2blepharitis29.3CCL11, IL4, RNASE3
3conjunctivitis10.8
4bacterial gastritis10.3CCL11, RNASE3
5loeffler syndrome10.3CCL11, RNASE3
6eosinophilic gastroenteritis10.3CCL11, IL4
7hepatitis e10.3CCL11, IL4
8retroperitoneal germ cell neoplasm10.2CCL11, RNASE3
9lymphocytic colitis10.2LTF, RNASE3
10kyphoscoliotic heart disease10.2IL4, RNASE3
11balkan nephropathy10.2CCL11, RNASE3
12egg allergy10.2IL4, RNASE3
13anus disease10.2LTF, RNASE3
14status asthmaticus10.2IL4, RNASE3
15benign paroxysmal positional nystagmus10.2IL4, RNASE3
16submandibular gland disease10.1IL4, LTF
17goat milk allergy10.1IL4, RNASE3
18vernal conjunctivitis10.1
19hepatoid adenocarcinoma10.1IL4, RNASE3
20congenital disorder of glycosylation, type ih10.1CCL11, RNASE3
21collagen vi related muscular dystrophy10.1CMA1, RNASE3
22uterine corpus epithelioid leiomyosarcoma10.1CCL11, RNASE3
23rectum signet ring adenocarcinoma10.1CCL11, LTF
24hodgkin's lymphoma, nodular sclerosis10.1IL4, RNASE3
25juvenile dermatitis herpetiformis10.0CCL11, RNASE3
26wissler's syndrome10.0IL4, RNASE3
27keratoconjunctivitis10.0
28uterine corpus epithelioid leiomyoma10.0IL4, RNASE3
29spinal canal intradural extramedullary neoplasm9.9CCL11, IL4
30hypertensive encephalopathy9.9CCL11, IL4, LTF
31ptosis9.9
32vernal keratoconjunctivitis9.9
33superficial urinary bladder cancer9.9CCL11, IL4, RNASE3
34familial hyperlipidemia9.9CCL11, IL4, RNASE3
35disseminated eosinophilic collagen disease9.9CCL11, IL4, RNASE3
36enamel caries9.9CCL11, IL4, RNASE3
37acalculous cholecystitis9.9CCL11, IL4, RNASE3
38opioid abuse9.9CCL11, IL4, RNASE3
39nasopharyngitis9.9CCL11, IL4, RNASE3
40postcholecystectomy syndrome9.8CCL11, IL4, RNASE3
41chronic eosinophilic pneumonia9.8CCL11, IL4, RNASE3
42orbital plasma cell granuloma9.8CCL11, IL4, RNASE3
43arthus reaction9.8CCL11, CMA1
44kohler's disease9.8CCL11, IL4, RNASE3
45reactive arthritis9.8CCL11, IL4, RNASE3
46diffuse scleroderma9.8CCL11, IL4, RNASE3
47severe acute respiratory syndrome9.8CCL11, IL4, RNASE3
48cryptococcosis9.8CCL11, IL4, RNASE3
49hypoglycemia9.8CCL11, IL4, RNASE3
50malignant biphasic mesothelioma9.8CCL11, IL4, RNASE3

Graphical network of the top 20 diseases related to Papillary Conjunctivitis:



Diseases related to papillary conjunctivitis

Symptoms for Papillary Conjunctivitis

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Drugs & Therapeutics for Papillary Conjunctivitis

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Drugs for Papillary Conjunctivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Loteprednol EtabonatePhase 44482034-46-6444025
Synonyms:
82034-46-6
AC1L9FKJ
AKOS005145741
Alrex
Alrex, Lotemax, Loteprednol etabonate
CDDD-5604
CHEBI:31784
CHEMBL1200865
CID444025
CPD000469178
D01689
DB00873
HGP-1
HMS2051F16
IDR-90102
IDR-90103
 
Locort
Loteflam
Lotemax
Lotemax (TN)
Loteprednol etabonate
Loteprednol etabonate (JAN/USAN)
Loterox
MLS001424221
MolPort-003-848-424
NCGC00164594-01
P-5604
S1669_Selleck
SAM001246630
SMR000469178
ZINC03920673
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
2Histamine H1 AntagonistsPhase 4688
3Histamine AntagonistsPhase 4826
4Anti-Allergic AgentsPhase 41312

Interventional clinical trials:

idNameStatusNCT IDPhase
1Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic ConjunctivitisCompletedNCT01443442Phase 4
2A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%Active, not recruitingNCT01437982Phase 4
3Clinical Performance of Atypical Contact Lens Powers on Subjects With AstigmatismCompletedNCT00697190
4Assessment of Daily Disposable Silicone Hydrogel Lens WearCompletedNCT01093625
5Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.CompletedNCT00708032
6BIOCLEAN FIRST CARE EX in Combination With Biofinity LensCompletedNCT02196766
7Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy PatientsRecruitingNCT02503956
8Daily Disposable Silicone Hydrogel Contact Lens, Stenfilcon A, Clinical StudyActive, not recruitingNCT02637804

Search NIH Clinical Center for Papillary Conjunctivitis

Genetic Tests for Papillary Conjunctivitis

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Anatomical Context for Papillary Conjunctivitis

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MalaCards organs/tissues related to Papillary Conjunctivitis:

33
Eye, Heart, Prostate, Thyroid, T cells, Myeloid, B cells

Animal Models for Papillary Conjunctivitis or affiliated genes

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MGI Mouse Phenotypes related to Papillary Conjunctivitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.6CCL11, CMA1, FPR1, IL4, LTF
2MP:00053877.3CCL11, CMA1, FPR1, IL4, LTF

Publications for Papillary Conjunctivitis

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Articles related to Papillary Conjunctivitis:

(show top 50)    (show all 118)
idTitleAuthorsYear
1
Risk factors for contact lens-induced papillary conjunctivitis associated with silicone hydrogel contact lens wear. (24681609)
2014
2
Comparison of tacrolimus, fluorometholone, and saline in mild-to-moderate contact lens-induced papillary conjunctivitis. (22821643)
2012
3
Comparison of olopatadine and fluorometholone in contact lens-induced papillary conjunctivitis. (20531202)
2010
4
Contact lens induced papillary conjunctivitis with silicone hydrogel lenses. (19181562)
2009
5
Giant papillary conjunctivitis. (18769199)
2008
6
Filtering bleb-induced giant papillary conjunctivitis. (17826299)
2008
7
Antibody array-generated cytokine profiles of tears of patients with vernal keratoconjunctivitis or giant papillary conjunctivitis. (16767372)
2006
8
Conjunctival cytology features of giant papillary conjunctivitis associated with ocular prostheses. (15677951)
2005
9
Contact lens chemistry and giant papillary conjunctivitis. (12772728)
2003
10
Tear eotaxin levels in giant papillary conjunctivitis associated with ocular prosthesis. (14566648)
2003
11
General and local contact lens induced papillary conjunctivitis (CLPC). (12033982)
2002
12
Nitric oxide levels in tears of patients with mild forms of papillary conjunctivitis induced by rigid gas-permeable contact lenses. (11838991)
2002
13
Giant papillary conjunctivitis associated with an ocular prosthesis. (12366372)
2001
14
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study (10844086)
2000
15
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study. (10703125)
1999
16
Sebaceous carcinoma presenting as a unilateral papillary conjunctivitis. (10218701)
1999
17
Giant papillary conjunctivitis--a review. (10337425)
1999
18
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. The Loteprednol Etabonate Giant Papillary Conjunctivitis Study Group I. (9124242)
1997
19
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. (9001768)
1997
20
Increased numbers of Langerhans cell and expression of HLA-Dr antigen in the giant papilla of patients with giant papillary conjunctivitis. (8755197)
1996
21
A rare case of chronic papillary conjunctivitis diagnosed after several years of evolution. Clinical and pathological findings. (8044334)
1993
22
Causative factors in unilateral giant papillary conjunctivitis. (8495560)
1993
23
Comparison of the clinical performance of the Acuvue disposable contact lens and CSI lens in patients with giant papillary conjunctivitis. (8470716)
1993
24
N-acetyl-aspartyl glutamic acid (NAAGA) topical eyedrops in the treatment of giant papillary conjunctivitis (GPC). (7910133)
1993
25
Unusual causes of giant papillary conjunctivitis. (8458237)
1993
26
Giant papillary conjunctivitis and meibomian gland dysfunction blepharitis. (1499122)
1992
27
Neutrophil chemotactic factors in the tears of giant papillary conjunctivitis patients. (1846131)
1991
28
Continued contact lens wear in patients with giant papillary conjunctivitis. (1904798)
1991
29
Human conjunctival mast cells: distribution of MCT and MCTC in vernal conjunctivitis and giant papillary conjunctivitis. (2196302)
1990
30
Giant papillary conjunctivitis. (2193971)
1990
31
Protein and elemental analysis of contact lenses of patients with superior limbic keratoconjunctivitis or giant papillary conjunctivitis. (2717140)
1989
32
Conjunctival deposition of eosinophil granule major basic protein in vernal keratoconjunctivitis and contact lens-associated giant papillary conjunctivitis. (2750834)
1989
33
Immune responses in monkeys to lenses from patients with contact lens induced giant papillary conjunctivitis. (2917401)
1989
34
Giant papillary conjunctivitis associated with rigid gas permeable contact lenses. (3208429)
1988
35
Giant papillary conjunctivitis. (3053490)
1988
36
Papillary conjunctivitis induced by an epithelialized corneal foreign body. (3362510)
1988
37
A review of contact lens induced giant papillary conjunctivitis. (3336050)
1988
38
Giant papillary conjunctivitis. (3949453)
1986
39
Giant papillary conjunctivitis from an exposed prolene suture. (3756614)
1986
40
Suture barb giant papillary conjunctivitis. (6709289)
1984
41
Giant papillary conjunctivitis following cataract extraction. (6367598)
1984
42
Tear immunoglobulins in giant papillary conjunctivitis induced by contact lenses. (6702985)
1984
43
Clinical aspects of giant papillary conjunctivitis. (7339618)
1981
44
Percentage of degranulated mast cells in vernal conjunctivitis and giant papillary conjunctivitis associated with contact-lens wear. (7234932)
1981
45
Giant papillary conjunctivitis after keratoplasty. (7008616)
1981
46
Giant papillary conjunctivitis with ocular prostheses. (7362515)
1980
47
Giant papillary conjunctivitis: an overview. (448014)
1979
48
Giant papillary conjunctivitis and ptosis in a contact lens wearer. (458521)
1979
49
Epidemic keratoconjunctivitis and chronic papillary conjunctivitis in London due to adenovirus type 19. (191054)
1977
50

Variations for Papillary Conjunctivitis

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Expression for genes affiliated with Papillary Conjunctivitis

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Search GEO for disease gene expression data for Papillary Conjunctivitis.

Pathways for genes affiliated with Papillary Conjunctivitis

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GO Terms for genes affiliated with Papillary Conjunctivitis

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Biological processes related to Papillary Conjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1innate immune response in mucosaGO:00022279.6IL4, LTF
2chemotaxisGO:00069359.2CCL11, IL4
3immune responseGO:00069558.9CCL11, CMA1, IL4

Sources for Papillary Conjunctivitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet