MCID: PPL019
MIFTS: 38

Papillary Conjunctivitis malady

Eye diseases category
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Summaries for Papillary Conjunctivitis

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MalaCards based summary: Papillary Conjunctivitis is related to conjunctivitis and vernal keratoconjunctivitis. An important gene associated with Papillary Conjunctivitis is CCL11 (chemokine (C-C motif) ligand 11), and among its related pathways are IL4-mediated signaling events and Development IGF 1 receptor signaling. The compounds unicap and anti-histamine have been mentioned in the context of this disorder. Affiliated tissues include eye and neutrophil, and related mouse phenotypes are respiratory system and hematopoietic system.

Aliases & Classifications for Papillary Conjunctivitis

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Papillary Conjunctivitis, Aliases & Descriptions:

Name: Papillary Conjunctivitis 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


External Ids:

Disease Ontology8 DOID:2458
SNOMED-CT57 416878008
NCIt39 C35616

Related Diseases for Papillary Conjunctivitis

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Graphical network of the top 20 diseases related to Papillary Conjunctivitis:



Diseases related to papillary conjunctivitis

Symptoms for Papillary Conjunctivitis

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Drugs & Therapeutics for Papillary Conjunctivitis

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Drug clinical trials:

Search ClinicalTrials for Papillary Conjunctivitis

Search NIH Clinical Center for Papillary Conjunctivitis

Genetic Tests for Papillary Conjunctivitis

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Anatomical Context for Papillary Conjunctivitis

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MalaCards organs/tissues related to Papillary Conjunctivitis:

32
Eye, Neutrophil

Animal Models for Papillary Conjunctivitis or affiliated genes

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MGI Mouse Phenotypes related to Papillary Conjunctivitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.5CCL11, CCL24, PRG2
2MP:00053977.9CCL11, CCL24, PRG2, IGHE
3MP:00053877.7IGHE, PRG2, CCL24, CCL11

Publications for Papillary Conjunctivitis

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Articles related to Papillary Conjunctivitis:

(show top 50)    (show all 116)
idTitleAuthorsYear
1
Risk factors for contact lens-induced papillary conjunctivitis associated with silicone hydrogel contact lens wear. (24681609)
2014
2
Comparison of tacrolimus, fluorometholone, and saline in mild-to-moderate contact lens-induced papillary conjunctivitis. (22821643)
2012
3
Contact lens induced papillary conjunctivitis with silicone hydrogel lenses. (19181562)
2009
4
Giant papillary conjunctivitis. (18769199)
2008
5
Filtering bleb-induced giant papillary conjunctivitis. (17826299)
2008
6
Antibody array-generated cytokine profiles of tears of patients with vernal keratoconjunctivitis or giant papillary conjunctivitis. (16767372)
2006
7
Conjunctival cytology features of giant papillary conjunctivitis associated with ocular prostheses. (15677951)
2005
8
Contact lens chemistry and giant papillary conjunctivitis. (12772728)
2003
9
Tear eotaxin levels in giant papillary conjunctivitis associated with ocular prosthesis. (14566648)
2003
10
General and local contact lens induced papillary conjunctivitis (CLPC). (12033982)
2002
11
Nitric oxide levels in tears of patients with mild forms of papillary conjunctivitis induced by rigid gas-permeable contact lenses. (11838991)
2002
12
Giant papillary conjunctivitis associated with an ocular prosthesis. (12366372)
2001
13
Delayed tear clearance in contact lens associated papillary conjunctivitis. (11462163)
2001
14
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study (10844086)
2000
15
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study. (10703125)
1999
16
Sebaceous carcinoma presenting as a unilateral papillary conjunctivitis. (10218701)
1999
17
Giant papillary conjunctivitis--a review. (10337425)
1999
18
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. The Loteprednol Etabonate Giant Papillary Conjunctivitis Study Group I. (9124242)
1997
19
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. (9001768)
1997
20
Increased numbers of Langerhans cell and expression of HLA-Dr antigen in the giant papilla of patients with giant papillary conjunctivitis. (8755197)
1996
21
A rare case of chronic papillary conjunctivitis diagnosed after several years of evolution. Clinical and pathological findings. (8044334)
1993
22
Causative factors in unilateral giant papillary conjunctivitis. (8495560)
1993
23
Comparison of the clinical performance of the Acuvue disposable contact lens and CSI lens in patients with giant papillary conjunctivitis. (8470716)
1993
24
N-acetyl-aspartyl glutamic acid (NAAGA) topical eyedrops in the treatment of giant papillary conjunctivitis (GPC). (7910133)
1993
25
Unusual causes of giant papillary conjunctivitis. (8458237)
1993
26
Giant papillary conjunctivitis and meibomian gland dysfunction blepharitis. (1499122)
1992
27
Neutrophil chemotactic factors in the tears of giant papillary conjunctivitis patients. (1846131)
1991
28
Continued contact lens wear in patients with giant papillary conjunctivitis. (1904798)
1991
29
Human conjunctival mast cells: distribution of MCT and MCTC in vernal conjunctivitis and giant papillary conjunctivitis. (2196302)
1990
30
Giant papillary conjunctivitis. (2193971)
1990
31
Some unusual nonallergic causes of giant papillary conjunctivitis. (2095029)
1990
32
Protein and elemental analysis of contact lenses of patients with superior limbic keratoconjunctivitis or giant papillary conjunctivitis. (2717140)
1989
33
Conjunctival deposition of eosinophil granule major basic protein in vernal keratoconjunctivitis and contact lens-associated giant papillary conjunctivitis. (2750834)
1989
34
Immune responses in monkeys to lenses from patients with contact lens induced giant papillary conjunctivitis. (2917401)
1989
35
Giant papillary conjunctivitis associated with rigid gas permeable contact lenses. (3208429)
1988
36
Giant papillary conjunctivitis. (3053490)
1988
37
Papillary conjunctivitis induced by an epithelialized corneal foreign body. (3362510)
1988
38
A review of contact lens induced giant papillary conjunctivitis. (3336050)
1988
39
Giant papillary conjunctivitis. (3949453)
1986
40
Giant papillary conjunctivitis from an exposed prolene suture. (3756614)
1986
41
Suture barb giant papillary conjunctivitis. (6709289)
1984
42
Giant papillary conjunctivitis following cataract extraction. (6367598)
1984
43
Tear immunoglobulins in giant papillary conjunctivitis induced by contact lenses. (6702985)
1984
44
Clinical aspects of giant papillary conjunctivitis. (7339618)
1981
45
Percentage of degranulated mast cells in vernal conjunctivitis and giant papillary conjunctivitis associated with contact-lens wear. (7234932)
1981
46
Giant papillary conjunctivitis after keratoplasty. (7008616)
1981
47
Giant papillary conjunctivitis with ocular prostheses. (7362515)
1980
48
Giant papillary conjunctivitis: an overview. (448014)
1979
49
Giant papillary conjunctivitis and ptosis in a contact lens wearer. (458521)
1979
50
Epidemic keratoconjunctivitis and chronic papillary conjunctivitis in London due to adenovirus type 19. (191054)
1977

Variations for Papillary Conjunctivitis

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Expression for genes affiliated with Papillary Conjunctivitis

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Expression patterns in normal tissues for genes affiliated with Papillary Conjunctivitis

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Pathways for genes affiliated with Papillary Conjunctivitis

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Pathways related to Papillary Conjunctivitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4CCL11, IGHE
2
Show member pathways
Immune response IL 4 signaling pathway60
Signal transduction AKT signaling60
9.4CCL11, IGHE
3
Show member pathways
9.3CCL11, CCL24
4
Show member pathways
9.3CCL24, CCL11
5
Show member pathways
9.3CCL11, CCL24
6
Show member pathways
9.3CCL11, CCL24
7
Show member pathways
9.1CCL11, PRG2
8
Show member pathways
8.5PRG2, CCL24, CCL11
9
Show member pathways
8.5CCL11, CCL24, PRG2

Compounds for genes affiliated with Papillary Conjunctivitis

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Compounds related to Papillary Conjunctivitis according to GeneCards/GeneDecks:

(show all 28)
idCompoundScoreTop Affiliating Genes
1unicap449.8CCL11, IGHE
2anti-histamine449.8CCL11, IGHE
3sodium cromoglycate449.8CCL11, IGHE
4cetirizine44 28 24 1112.8IGHE, CCL11
5ketotifen44 1110.7CCL11, IGHE
6montelukast44 50 28 1112.7IGHE, CCL11
7budesonide44 50 1111.7CCL11, IGHE
8salbutamol44 50 28 24 1113.7IGHE, CCL11
9fluticasone propionate44 50 61 1112.7IGHE, CCL11
10pertussis449.6CCL11, IGHE
11ccl344 2810.5CCL24, CCL11
12prednisolone44 28 1111.5IGHE, CCL11
13ltc4449.4CCL11, PRG2
14rantes449.2CCL11, CCL24
15tarc449.2CCL11, CCL24, IGHE
16fmlp449.1CCL11, PRG2
17n acetylcysteine449.1CCL11, IGHE
18acetylcholine44 50 28 24 1113.1PRG2, IGHE
19pgd2449.0IGHE, PRG2, CCL11
20methacholine44 50 1111.0CCL11, PRG2, IGHE
21allergens449.0IGHE, PRG2, CCL11
22indomethacin44 28 61 1111.9CCL11, PRG2, IGHE
23heparin44 28 24 1111.8CCL11, PRG2, IGHE
24superoxide44 249.8PRG2, CCL24, CCL11
25retinoic acid44 249.7CCL11, PRG2, IGHE
26oxygen44 249.7CCL11, CCL24, PRG2
27histamine44 28 2410.4CCL11, CCL24, PRG2, IGHE
28actinomycin d448.4CCL11, CCL24, PRG2, IGHE

GO Terms for genes affiliated with Papillary Conjunctivitis

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Cellular components related to Papillary Conjunctivitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.6CCL11, PRG2, IGHE

Biological processes related to Papillary Conjunctivitis according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1eosinophil chemotaxisGO:0482459.6CCL11, CCL24
2positive regulation of Rac GTPase activityGO:0328559.5CCL24, CCL11
3positive regulation of actin filament polymerizationGO:0308389.5CCL11, CCL24
4positive regulation of endothelial cell proliferationGO:0019389.5CCL11, CCL24
5positive regulation of angiogenesisGO:0457669.4CCL24, CCL11
6cytoskeleton organizationGO:0070109.4CCL11, CCL24
7regulation of cell shapeGO:0083609.3CCL11, CCL24
8inflammatory responseGO:0069549.3CCL11, CCL24
9chemotaxisGO:0069359.2CCL24, CCL11
10positive regulation of cell migrationGO:0303359.0CCL11, CCL24
11immune responseGO:0069558.2CCL11, CCL24, PRG2, IGHE

Molecular functions related to Papillary Conjunctivitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:0080099.3CCL11, CCL24

Products for genes affiliated with Papillary Conjunctivitis

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  • Proteins
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Sources for Papillary Conjunctivitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet