MCID: PPL039
MIFTS: 31

Papillary Glioneuronal Tumor

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Papillary Glioneuronal Tumor

MalaCards integrated aliases for Papillary Glioneuronal Tumor:

Name: Papillary Glioneuronal Tumor 56 69
Pseudopapillary Neurocytoma with Glial Differentiation 56
Pseudopapillary Ganglioglioneurocytoma 56
Pgnt 56

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Orphanet 56 ORPHA251962
UMLS via Orphanet 70 C2985174

Summaries for Papillary Glioneuronal Tumor

MalaCards based summary : Papillary Glioneuronal Tumor, also known as pseudopapillary neurocytoma with glial differentiation, is related to cavernous hemangioma and pediatric infratentorial ependymoma. An important gene associated with Papillary Glioneuronal Tumor is EGFR (Epidermal Growth Factor Receptor), and among its related pathways/superpathways are MicroRNAs in cancer and mTOR signaling pathway (KEGG). Affiliated tissues include pineal and brain, and related phenotypes are muscle and respiratory system

Related Diseases for Papillary Glioneuronal Tumor

Diseases related to Papillary Glioneuronal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
id Related Disease Score Top Affiliating Genes
1 cavernous hemangioma 29.4 GFAP SYP
2 pediatric infratentorial ependymoma 10.5 EGFR TP53
3 childhood infratentorial neoplasm 10.4 EGFR TP53
4 breast adenoid cystic carcinoma 10.4 EGFR PDGFRA
5 caroli disease 10.4 EGFR SYP
6 congenital granular cell tumor 10.4 SYP TP53
7 breast fibrosarcoma 10.4 EGFR TP53
8 hair disease 10.4 SYP TP53
9 rete testis neoplasm 10.4 EGFR PDGFRA
10 extragonadal nonseminomatous germ cell tumor 10.4 EGFR TP53
11 thymus small cell carcinoma 10.4 PDGFRA SYP
12 multiple carboxylase deficiency 10.4 EGFR TP53
13 sparse hair ptosis mental retardation 10.4 EGFR TP53
14 retinal detachment 10.4 SYP TP53
15 olfactory neural tumor 10.4 SYP TP53
16 pancreatic agenesis 10.4 SYP TP53
17 immune system organ benign neoplasm 10.4 SYP TP53
18 brainstem intraparenchymal clear cell meningioma 10.4 NES TP53
19 group b strep disease in newborns 10.4 SYP TP53
20 glomangioma 10.3 SYP TP53
21 migraine with aura 10.3 SYP TP53
22 gorham's disease 10.3 EGFR PDGFRA
23 hypersensitivity reaction type iii disease 10.3 SYP TP53
24 biliary dyskinesia 10.3 SYP TP53
25 spinal cord dermoid cyst 10.3 EGFR TP53
26 hip subluxation 10.3 EGFR TP53
27 distal monosomy 7q36 10.3 EGFR TP53
28 internal auditory canal lipoma 10.3 SYP TP53
29 bone development disease 10.3 SYP TP53
30 secondary hyperparathyroidism of renal origin 10.3 EGFR TP53
31 vulvar keratoacanthoma-like carcinoma 10.3 SYP TP53
32 rectum kaposi's sarcoma 10.3 EGFR TP53
33 molluscum contagiosum 10.3 EGFR TP53
34 lacrimal gland mucoepidermoid carcinoma 10.2 EGFR TP53
35 mixed oligodendroglioma-astrocytoma 10.2 IDH1 TP53
36 pilocytic astrocytoma of cerebellum 10.2 IDH1 TP53
37 congenital disorder of glycosylation, type if 10.2 IDH1 TP53
38 ductal carcinoma in situ 10.2 EGFR TP53
39 cecum adenocarcinoma 10.2 EGFR TP53
40 breast epithelioid hemangioma 10.2 IDH1 TP53
41 fallopian tube papillary adenocarcinoma 10.1 IDH1 SYP
42 devriendt syndrome 10.1 GFAP SYP
43 dystonia 10.1 GFAP SYP
44 spinal cord ependymoma 10.1 GFAP SYP
45 chilaiditi syndrome 10.1 GFAP SYP
46 cerebellar astrocytoma 10.1 GFAP SYP
47 epidermal appendage tumor 10.1 GFAP SYP
48 reticular pattern testicular yolk sac tumor 10.1 GFAP SYP
49 vulva adenocarcinoma 10.1 SYP TP53
50 cauda equina intradural extramedullary astrocytoma 10.1 GFAP SYP

Graphical network of the top 20 diseases related to Papillary Glioneuronal Tumor:



Diseases related to Papillary Glioneuronal Tumor

Symptoms & Phenotypes for Papillary Glioneuronal Tumor

MGI Mouse Phenotypes related to Papillary Glioneuronal Tumor:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.35 EGFR GFAP OLIG2 PDGFRA TP53
2 respiratory system MP:0005388 9.02 EGFR IDH1 OLIG2 PDGFRA TP53

Drugs & Therapeutics for Papillary Glioneuronal Tumor

Search Clinical Trials , NIH Clinical Center for Papillary Glioneuronal Tumor

Genetic Tests for Papillary Glioneuronal Tumor

Anatomical Context for Papillary Glioneuronal Tumor

MalaCards organs/tissues related to Papillary Glioneuronal Tumor:

39
Pineal, Brain

Publications for Papillary Glioneuronal Tumor

Articles related to Papillary Glioneuronal Tumor:

(show all 48)
id Title Authors Year
1
Surgical resection and cellular proliferation index predict prognosis for patients with papillary glioneuronal tumor (PGNT): a systematic review and pooled analysis. ( 28823671 )
2017
2
Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion. ( 26671581 )
2015
3
Recurrent papillary glioneuronal tumor presenting as a ganglioglioma with the BRAF V600E mutation. ( 26073619 )
2015
4
Papillary glioneuronal tumor: case report and review of literature. ( 26017104 )
2015
5
Papillary glioneuronal tumor with a high proliferative component and minigemistocytes in a child. ( 24738632 )
2014
6
FGFR1 N546K mutation in a case of papillary glioneuronal tumor (PGNT). ( 24777483 )
2014
7
Solid intraventricular papillary glioneuronal tumor: magnetic resonance imaging findings with histopathological correlation. ( 24314675 )
2014
8
Anaplastic papillary glioneuronal tumor with extraneural metastases. ( 24709681 )
2014
9
Neuroradiological features of papillary glioneuronal tumor: a study of 8 cases. ( 24879457 )
2014
10
An individual patient data meta-analysis on characteristics and outcome of patients with papillary glioneuronal tumor, rosette glioneuronal tumor with neuropil-like islands and rosette forming glioneuronal tumor of the fourth ventricle. ( 24991807 )
2014
11
Papillary glioneuronal tumor with an unusual bilateral intraventricular localization. ( 25250653 )
2014
12
Hemorrhagic papillary glioneuronal tumor mimicking cavernoma: two case reports. ( 22717600 )
2013
13
Identification of a novel, recurrent SLC44A1-PRKCA fusion in papillary glioneuronal tumor. ( 22725730 )
2013
14
Malignant papillary glioneuronal tumor of the pineal gland: Case presentation and literature review of a distinct entity. ( 23826458 )
2013
15
Bilateral non-contiguous atypical papillary glioneuronal tumor: case report. ( 22385788 )
2012
16
Papillary glioneuronal tumor--a rare entity: report of four cases and brief review of literature. ( 22868530 )
2012
17
Papillary glioneuronal tumor: unexplored entity. ( 21842459 )
2012
18
Papillary glioneuronal tumor: radiological evidence of a newly established tumor entity. ( 20331495 )
2011
19
Papillary glioneuronal tumor present in a patient with encephalocraniocutaneous lipomatosis: case report. ( 20881536 )
2010
20
Papillary glioneuronal tumor of the fourth ventricle: case report and review of the literature. ( 20843438 )
2010
21
Papillary glioneuronal tumor of the frontal lobe. ( 20156688 )
2010
22
Papillary glioneuronal tumor--prognostic value of the extension of surgical resection. ( 19642508 )
2009
23
Papillary glioneuronal tumor-evidence of stem cell origin with biphenotypic differentiation. ( 19404583 )
2009
24
Endoscopic diagnosis of a pineal papillary glioneuronal tumor with extensive ventricular involvement: case report with review of literature. ( 20139514 )
2009
25
Aggressive variant of a papillary glioneuronal tumor. Report of 2 cases. ( 19119904 )
2009
26
Aggressive papillary glioneuronal tumor: case report and literature review. ( 18808063 )
2008
27
Papillary glioneuronal tumor--contribution to a new tumor entity and literature review. ( 18402385 )
2008
28
Genetic alterations in a papillary glioneuronal tumor. ( 18352813 )
2008
29
Papillary glioneuronal tumor: a case report and review of the literature. ( 18715860 )
2008
30
Papillary glioneuronal tumor: not always a benign tumor? ( 19157003 )
2007
31
Papillary glioneuronal tumor: a new entity awaiting inclusion in WHO classification. ( 17288594 )
2007
32
Atypical papillary glioneuronal tumor. ( 17285229 )
2007
33
Papillary glioneuronal tumor. ( 18018482 )
2007
34
Papillary glioneuronal tumor. Case report and literature review. ( 16703452 )
2006
35
Papillary glioneuronal tumor: a case report and review of the literature. ( 16784993 )
2006
36
Papillary glioneuronal tumor. ( 16413693 )
2006
37
Papillary glioneuronal tumor radiologically mimicking a cavernous hemangioma with hemorrhagic onset. ( 16771176 )
2006
38
Superficial siderosis due to papillary glioneuronal tumor. ( 17049863 )
2006
39
Papillary glioneuronal tumor: a clinicopathological and immunohistochemical study of two cases. ( 16771182 )
2006
40
Papillary glioneuronal tumor with minigemistocytic components and increased proliferative activity. ( 16647962 )
2006
41
A distinct pattern of Olig2-positive cellular distribution in papillary glioneuronal tumors: a manifestation of the oligodendroglial phenotype? ( 15906048 )
2005
42
Papillary glioneuronal tumor. ( 15972434 )
2005
43
Long term follow-up in a patient with papillary glioneuronal tumor. ( 15476085 )
2004
44
Papillary glioneuronal tumor--a new variant of benign mixed brain neoplasm. ( 12817884 )
2003
45
A papillary glioneuronal tumor arising in an elderly woman: a case report. ( 12455887 )
2002
46
Papillary glioneuronal tumor--a new tumor entity. ( 11846038 )
2002
47
Papillary glioneuronal tumor. ( 11100065 )
2000
48
Papillary glioneuronal tumor: a new variant of mixed neuronal-glial neoplasm. ( 9777979 )
1998

Variations for Papillary Glioneuronal Tumor

Expression for Papillary Glioneuronal Tumor

Search GEO for disease gene expression data for Papillary Glioneuronal Tumor.

Pathways for Papillary Glioneuronal Tumor

GO Terms for Papillary Glioneuronal Tumor

Cellular components related to Papillary Glioneuronal Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.62 GFAP NES

Biological processes related to Papillary Glioneuronal Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.35 EGFR NES OLIG2 PDGFRA TP53
2 positive regulation of DNA replication GO:0045740 9.32 EGFR PDGFRA
3 cellular response to reactive oxygen species GO:0034614 9.26 EGFR PDGFRA
4 female gonad development GO:0008585 8.85 IDH1
5 phosphatidylinositol-mediated signaling GO:0048015 8.8 EGFR PDGFRA TP53

Molecular functions related to Papillary Glioneuronal Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 EGFR GFAP SYP TP53

Sources for Papillary Glioneuronal Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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