MCID: PPL007
MIFTS: 33

Papillary Serous Adenocarcinoma malady

Cancer diseases category

Aliases & Classifications for Papillary Serous Adenocarcinoma

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Aliases & Descriptions for Papillary Serous Adenocarcinoma:

Name: Papillary Serous Adenocarcinoma 8
Serous Surface Papillary Carcinoma 8 61
Papillary Serous Cystadenocarcinoma 61
 
Micropapillary Serous Carcinoma 8
Papillary Serous Carcinoma 8


Classifications:



External Ids:

Disease Ontology8 DOID:2632
SNOMED-CT56 15674004, 90282004
NCIt39 C8377, C6882

Summaries for Papillary Serous Adenocarcinoma

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Disease Ontology:8 A papillary adenocarcinoma that derives from epithelial cells originating in glandular tissue, which form complex papillary structures with psammoma bodies.

MalaCards based summary: Papillary Serous Adenocarcinoma, also known as serous surface papillary carcinoma, is related to adenofibroma and malignant mixed mullerian tumor. An important gene associated with Papillary Serous Adenocarcinoma is NKX2-1 (NK2 homeobox 1). The compounds topotecan and megestrol acetate have been mentioned in the context of this disorder. Affiliated tissues include ovary, cervix and breast.

Related Diseases for Papillary Serous Adenocarcinoma

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Diseases related to Papillary Serous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1adenofibroma30.9MUC16
2malignant mixed mullerian tumor30.1PGR, ERBB2, KRT7
3adenocarcinoma30.1PGR, MUC16, ANXA4, NKX2-1, ERBB2, KRT7
4endometrial cancer30.0ERBB2, MUC16, PGR
5papillary carcinoma29.8PGR, MUC16, NKX2-1, ERBB2, KRT7, KRT20
6breast cancer29.5KRT7, ERBB2, MUC16, PGR
7primary peritoneal carcinoma10.6
8peritonitis10.5
9secretory meningioma10.4KRT7
10cystadenoma10.4KRT7
11bronchogenic cyst10.4MUC16
12cystadenocarcinoma10.4MUC16
13ovarian serous cystadenocarcinoma10.4MUC16
14ovary papillary carcinoma10.3
15merkel cell carcinoma10.3NKX2-1, KRT20
16thymic carcinoma10.3NKX2-1, KRT7
17hereditary breast ovarian cancer10.2
18bilateral breast cancer10.2
19panniculitis10.2
20vaginitis10.2
21gastric outlet obstruction10.2
22bladder adenocarcinoma10.2KRT20, KRT7
23ovarian brenner tumor10.2KRT7, KRT20
24signet ring cell adenocarcinoma10.2KRT7, KRT20
25struma ovarii10.2MUC16, NKX2-1
26pancreatic ductal carcinoma10.2KRT7, KRT20
27papillary adenocarcinoma10.2MUC16, NKX2-1
28lymphangioleiomyomatosis10.2
29pulmonary fibrosis10.2
30neuroendocrine carcinoma10.2
31endometrial stromal nodule10.2
32ovarian serous carcinoma10.2
33thrombocytosis10.2
34large cell neuroendocrine carcinoma10.2
35tuberculous peritonitis10.2
36multicentric reticulohistiocytosis10.2
37tuberous sclerosis10.2
38uterine corpus serous adenocarcinoma10.2
39endocervicitis10.2
40angiomyolipoma10.2
41endometriosis10.2
42leiomyoma10.2
43uterine disease10.2
44adenomyosis10.2
45cerebellar degeneration10.2
46paraneoplastic cerebellar degeneration10.2
47follicular adenoma10.2NKX2-1, KRT20
48pseudomyxoma peritonei10.2KRT7, KRT20
49teratoma10.2NKX2-1, KRT7
50neuroendocrine tumor10.2KRT20, NKX2-1

Graphical network of the top 20 diseases related to Papillary Serous Adenocarcinoma:



Diseases related to papillary serous adenocarcinoma

Symptoms for Papillary Serous Adenocarcinoma

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Drugs & Therapeutics for Papillary Serous Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Papillary Serous Adenocarcinoma

Search NIH Clinical Center for Papillary Serous Adenocarcinoma

Genetic Tests for Papillary Serous Adenocarcinoma

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Anatomical Context for Papillary Serous Adenocarcinoma

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MalaCards organs/tissues related to Papillary Serous Adenocarcinoma:

31
Ovary, Cervix, Breast, Brain

Animal Models for Papillary Serous Adenocarcinoma or affiliated genes

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Publications for Papillary Serous Adenocarcinoma

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Articles related to Papillary Serous Adenocarcinoma:

(show all 31)
idTitleAuthorsYear
1
Multiple brain metastases in a patient with uterine papillary serous adenocarcinoma: Treatment options for this rarely seen metastatic brain tumor. (24032086)
2013
2
Overexpression of annexin A4 is associated with chemoresistance in papillary serous adenocarcinoma of the ovary. (23290009)
2013
3
Malignant mixed mullerian tumor of endometrium coexisting with bilateral papillary serous adenocarcinoma of fallopian tube: a rare case report. (24293882)
2012
4
F-18 fluoride uptake in calcified extraosseous metastases from ovarian papillary serous adenocarcinoma. (22157054)
2012
5
Papillary-serous adenocarcinoma of the uterine cervix during tamoxifen therapy after bilateral breast cancer. (23155282)
2012
6
Papillary serous adenocarcinoma of the uterine cervix: a case report. (21614930)
2011
7
Acute gastric outlet obstruction secondary to papillary serous adenocarcinoma of the endometrium with peritoneal psammomatous implants: a case report. (19132421)
2010
8
Successful Treatment of Primary Vaginal Papillary Serous Adenocarcinoma Using Chemoradiation Followed by Brachytherapy. (20740170)
2009
9
99mTc-MDP and 18F-FDG uptake in calcified metastatic lesions from ovarian papillary serous adenocarcinoma. (19936349)
2009
10
Malignant pericardial tamponade secondary to papillary serous adenocarcinoma of the ovary. (17491236)
2007
11
A long-term survivor of repeated inguinal nodes recurrence of papillary serous adenocarcinoma of CUP: case report. (16930493)
2006
12
Pulmonary papillary serous adenocarcinoma with intraperitoneal and ovarian tumors: identification of primary site. A case report. (16515596)
2006
13
Weekly topotecan in a heavily pretreated patient with peritoneal papillary serous adenocarcinoma. (15228430)
2004
14
Papillary serous adenocarcinoma of the endometrium: CT-pathologic correlation. (15150003)
2004
15
Establishment and characterization of two cell lines (HEC-155, HEC-180) derived from uterine papillary serous adenocarcinoma. (15285295)
2004
16
Papillary serous adenocarcinoma of the ovary diagnosed after malignant pericardial tamponade and embolic stroke. (11855887)
2002
17
Cerebellar metastasis from papillary serous adenocarcinoma of the ovary mimicking MAcniA"re's disease. A case report. (11304872)
2001
18
Papillary serous adenocarcinoma of the endocervix: A rare neoplasm. Immunohistochemical profile. (11240696)
2000
19
Is uterine papillary serous adenocarcinoma a manifestation of the hereditary breast-ovarian cancer syndrome? (11104623)
2000
20
The combination paclitaxel, carboplatin and megestrol acetate is effective in women with recurrent uterine papillary serous adenocarcinoma. (10422674)
1999
21
Multiple nodular metastases in mesenteric panniculitis by uterine papillary serous adenocarcinoma (UPSC): CT appearance of a case. (10416083)
1999
22
Supradiaphragmatic manifestations of papillary serous adenocarcinoma of the ovary. (10580766)
1999
23
Cytologic features of papillary serous adenocarcinoma of the uterine cervix. (9126137)
1997
24
Histologic characterization of uterine papillary serous adenocarcinoma. (7705679)
1995
25
Uterine papillary serous adenocarcinoma. A 10-case study of p53 and c-erbB-2 expression and DNA content. (7915964)
1994
26
Papillary serous adenocarcinoma of the uterine cervix: a report of three cases. (1495949)
1992
27
Papillary serous adenocarcinoma of the endometrium: a clinicopathologic study of 19 cases. (1634141)
1992
28
Primary peritoneal papillary serous adenocarcinoma: clinical and management aspects. (2013445)
1991
29
Invasive papillary serous adenocarcinoma of the endocervix in pregnancy; a case report. (1855609)
1991
30
Papillary serous adenocarcinoma of the endometrium. (3960439)
1986
31
Papillary serous adenocarcinoma. (18870241)
1948

Variations for Papillary Serous Adenocarcinoma

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Expression for genes affiliated with Papillary Serous Adenocarcinoma

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Search GEO for disease gene expression data for Papillary Serous Adenocarcinoma.

Pathways for genes affiliated with Papillary Serous Adenocarcinoma

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Compounds for genes affiliated with Papillary Serous Adenocarcinoma

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Compounds related to Papillary Serous Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 37)
idCompoundScoreTop Affiliating Genes
1topotecan44 1111.2MUC16
2megestrol acetate4410.0PGR, ERBB2
3capecitabine44 50 1112.0PGR, ERBB2
4exemestane44 50 60 1112.9PGR, ERBB2
5anastrozole44 50 1111.9PGR, ERBB2
6lapatinib44 50 1111.9ERBB2, PGR
7toremifene44 1110.9ERBB2, PGR
8fulvestrant44 50 28 1112.9ERBB2, PGR
9taxane449.9PGR, ERBB2
10letrozole44 50 60 1112.9ERBB2, PGR
11leucovorin44 50 1111.8ERBB2, PGR
12raloxifene44 50 28 1112.7PGR, ERBB2
13trastuzumab44 50 1111.7PGR, ERBB2
144-hydroxytamoxifen449.6PGR, ERBB2
15geldanamycin44 50 60 1112.6PGR, ERBB2
16gnrh449.6NKX2-1, PGR, ERBB2
17progestin449.5ERBB2, PGR
18cyclophosphamide44 50 1111.5MUC16, ERBB2, PGR
19ribonucleic acid449.4KRT20, NKX2-1, PGR
20paclitaxel44 50 1111.3MUC16, ERBB2, PGR
21streptavidin449.3KRT20, KRT7
22carboplatin44 50 1111.2ERBB2, MUC16
23methotrexate50 44 1111.1ERBB2, KRT7, PGR
24steroid449.1PGR, MUC16, NKX2-1, ERBB2
25dexamethasone44 50 28 1112.1NKX2-1, ERBB2, PGR, MUC16
26mucicarmine449.1KRT20, KRT7, NKX2-1
27doxorubicin44 50 1110.8KRT20, MUC16, PGR, ERBB2
28iron44 249.7KRT7, KRT20, MUC16
29formaldehyde44 249.6KRT20, KRT7, ERBB2, NKX2-1
30b 723448.5KRT20, KRT7, NKX2-1, MUC16
31hematoxylin448.5KRT20, MUC16, NKX2-1, KRT7
32testosterone44 60 24 1111.0KRT7, ERBB2, MUC16, PGR, KRT20
33vegf448.0KRT20, MUC16, ERBB2, KRT7, PGR
34paraffin447.7ERBB2, PGR, MUC16, NKX2-1, KRT20, KRT7
35progesterone44 28 60 24 1111.7PGR, MUC16, NKX2-1, ERBB2, KRT7, KRT20
36estrogen447.7MUC16, KRT20, KRT7, ERBB2, NKX2-1, PGR
37tyrosine447.5MUC16, ANXA4, NKX2-1, KRT7, KRT20, ERBB2

GO Terms for genes affiliated with Papillary Serous Adenocarcinoma

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Cellular components related to Papillary Serous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.0KRT20, KRT7

Molecular functions related to Papillary Serous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055157.3KRT20, KRT7, ERBB2, NKX2-1, MUC16, PGR

Sources for Papillary Serous Adenocarcinoma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet