MCID: PPL007
MIFTS: 33

Papillary Serous Adenocarcinoma malady

Cancer diseases category

Summaries for Papillary Serous Adenocarcinoma

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Disease Ontology:9 A papillary adenocarcinoma that derives from epithelial cells originating in glandular tissue, which form complex papillary structures with psammoma bodies.

MalaCards based summary: Papillary Serous Adenocarcinoma, also known as serous surface papillary carcinoma, is related to adenofibroma and malignant mixed mullerian tumor. An important gene associated with Papillary Serous Adenocarcinoma is NKX2-1 (NK2 homeobox 1). The compounds topotecan and megestrol acetate have been mentioned in the context of this disorder. Affiliated tissues include ovary, cervix and breast.

Aliases & Classifications for Papillary Serous Adenocarcinoma

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Papillary Serous Adenocarcinoma, Aliases & Descriptions:

Name: Papillary Serous Adenocarcinoma 9
Serous Surface Papillary Carcinoma 9 60
Papillary Serous Cystadenocarcinoma 60
 
Micropapillary Serous Carcinoma 9
Papillary Serous Carcinoma 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology9 DOID:2632
SNOMED-CT55 15674004, 90282004
NCIt38 C8377, C6882

Related Diseases for Papillary Serous Adenocarcinoma

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Diseases related to Papillary Serous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1adenofibroma30.9MUC16
2malignant mixed mullerian tumor30.1PGR, ERBB2, KRT7
3adenocarcinoma30.1PGR, MUC16, ANXA4, NKX2-1, ERBB2, KRT7
4endometrial cancer30.0ERBB2, MUC16, PGR
5papillary carcinoma29.8PGR, MUC16, NKX2-1, ERBB2, KRT7, KRT20
6breast cancer29.5KRT7, ERBB2, MUC16, PGR
7primary peritoneal carcinoma10.6
8peritonitis10.5
9secretory meningioma10.4KRT7
10cystadenoma10.4KRT7
11bronchogenic cyst10.4MUC16
12cystadenocarcinoma10.4MUC16
13ovarian serous cystadenocarcinoma10.4MUC16
14ovary papillary carcinoma10.3
15merkel cell carcinoma10.3NKX2-1, KRT20
16thymic carcinoma10.3NKX2-1, KRT7
17hereditary breast ovarian cancer10.2
18bilateral breast cancer10.2
19panniculitis10.2
20vaginitis10.2
21gastric outlet obstruction10.2
22bladder adenocarcinoma10.2KRT20, KRT7
23ovarian brenner tumor10.2KRT7, KRT20
24signet ring cell adenocarcinoma10.2KRT7, KRT20
25struma ovarii10.2MUC16, NKX2-1
26pancreatic ductal carcinoma10.2KRT7, KRT20
27papillary adenocarcinoma10.2MUC16, NKX2-1
28lymphangioleiomyomatosis10.2
29pulmonary fibrosis10.2
30neuroendocrine carcinoma10.2
31endometrial stromal nodule10.2
32ovarian serous carcinoma10.2
33thrombocytosis10.2
34large cell neuroendocrine carcinoma10.2
35tuberculous peritonitis10.2
36multicentric reticulohistiocytosis10.2
37tuberous sclerosis10.2
38uterine corpus serous adenocarcinoma10.2
39endocervicitis10.2
40angiomyolipoma10.2
41endometriosis10.2
42leiomyoma10.2
43uterine disease10.2
44adenomyosis10.2
45cerebellar degeneration10.2
46paraneoplastic cerebellar degeneration10.2
47follicular adenoma10.2NKX2-1, KRT20
48pseudomyxoma peritonei10.2KRT7, KRT20
49teratoma10.2NKX2-1, KRT7
50neuroendocrine tumor10.2KRT20, NKX2-1

Graphical network of the top 20 diseases related to Papillary Serous Adenocarcinoma:



Diseases related to papillary serous adenocarcinoma

Symptoms for Papillary Serous Adenocarcinoma

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Drugs & Therapeutics for Papillary Serous Adenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Papillary Serous Adenocarcinoma

Search NIH Clinical Center for Papillary Serous Adenocarcinoma

Genetic Tests for Papillary Serous Adenocarcinoma

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Anatomical Context for Papillary Serous Adenocarcinoma

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MalaCards organs/tissues related to Papillary Serous Adenocarcinoma:

31
Ovary, Cervix, Breast, Brain

Animal Models for Papillary Serous Adenocarcinoma or affiliated genes

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Publications for Papillary Serous Adenocarcinoma

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Articles related to Papillary Serous Adenocarcinoma:

(show all 31)
idTitleAuthorsYear
1
Multiple brain metastases in a patient with uterine papillary serous adenocarcinoma: Treatment options for this rarely seen metastatic brain tumor. (24032086)
2013
2
Overexpression of annexin A4 is associated with chemoresistance in papillary serous adenocarcinoma of the ovary. (23290009)
2013
3
Malignant mixed mullerian tumor of endometrium coexisting with bilateral papillary serous adenocarcinoma of fallopian tube: a rare case report. (24293882)
2012
4
F-18 fluoride uptake in calcified extraosseous metastases from ovarian papillary serous adenocarcinoma. (22157054)
2012
5
Papillary-serous adenocarcinoma of the uterine cervix during tamoxifen therapy after bilateral breast cancer. (23155282)
2012
6
Papillary serous adenocarcinoma of the uterine cervix: a case report. (21614930)
2011
7
Acute gastric outlet obstruction secondary to papillary serous adenocarcinoma of the endometrium with peritoneal psammomatous implants: a case report. (19132421)
2010
8
Successful Treatment of Primary Vaginal Papillary Serous Adenocarcinoma Using Chemoradiation Followed by Brachytherapy. (20740170)
2009
9
99mTc-MDP and 18F-FDG uptake in calcified metastatic lesions from ovarian papillary serous adenocarcinoma. (19936349)
2009
10
Malignant pericardial tamponade secondary to papillary serous adenocarcinoma of the ovary. (17491236)
2007
11
A long-term survivor of repeated inguinal nodes recurrence of papillary serous adenocarcinoma of CUP: case report. (16930493)
2006
12
Pulmonary papillary serous adenocarcinoma with intraperitoneal and ovarian tumors: identification of primary site. A case report. (16515596)
2006
13
Weekly topotecan in a heavily pretreated patient with peritoneal papillary serous adenocarcinoma. (15228430)
2004
14
Papillary serous adenocarcinoma of the endometrium: CT-pathologic correlation. (15150003)
2004
15
Establishment and characterization of two cell lines (HEC-155, HEC-180) derived from uterine papillary serous adenocarcinoma. (15285295)
2004
16
Papillary serous adenocarcinoma of the ovary diagnosed after malignant pericardial tamponade and embolic stroke. (11855887)
2002
17
Cerebellar metastasis from papillary serous adenocarcinoma of the ovary mimicking MAcniA"re's disease. A case report. (11304872)
2001
18
Papillary serous adenocarcinoma of the endocervix: A rare neoplasm. Immunohistochemical profile. (11240696)
2000
19
Is uterine papillary serous adenocarcinoma a manifestation of the hereditary breast-ovarian cancer syndrome? (11104623)
2000
20
The combination paclitaxel, carboplatin and megestrol acetate is effective in women with recurrent uterine papillary serous adenocarcinoma. (10422674)
1999
21
Multiple nodular metastases in mesenteric panniculitis by uterine papillary serous adenocarcinoma (UPSC): CT appearance of a case. (10416083)
1999
22
Supradiaphragmatic manifestations of papillary serous adenocarcinoma of the ovary. (10580766)
1999
23
Cytologic features of papillary serous adenocarcinoma of the uterine cervix. (9126137)
1997
24
Histologic characterization of uterine papillary serous adenocarcinoma. (7705679)
1995
25
Uterine papillary serous adenocarcinoma. A 10-case study of p53 and c-erbB-2 expression and DNA content. (7915964)
1994
26
Papillary serous adenocarcinoma of the uterine cervix: a report of three cases. (1495949)
1992
27
Papillary serous adenocarcinoma of the endometrium: a clinicopathologic study of 19 cases. (1634141)
1992
28
Primary peritoneal papillary serous adenocarcinoma: clinical and management aspects. (2013445)
1991
29
Invasive papillary serous adenocarcinoma of the endocervix in pregnancy; a case report. (1855609)
1991
30
Papillary serous adenocarcinoma of the endometrium. (3960439)
1986
31
Papillary serous adenocarcinoma. (18870241)
1948

Variations for Papillary Serous Adenocarcinoma

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Expression for genes affiliated with Papillary Serous Adenocarcinoma

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Search GEO for disease gene expression data for Papillary Serous Adenocarcinoma.

Pathways for genes affiliated with Papillary Serous Adenocarcinoma

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Compounds for genes affiliated with Papillary Serous Adenocarcinoma

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Compounds related to Papillary Serous Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 37)
idCompoundScoreTop Affiliating Genes
1topotecan43 1211.2MUC16
2megestrol acetate4310.0PGR, ERBB2
3capecitabine43 49 1212.0ERBB2, PGR
4exemestane43 49 59 1212.9ERBB2, PGR
5anastrozole43 49 1211.9ERBB2, PGR
6lapatinib43 49 1211.9PGR, ERBB2
7toremifene43 1210.9ERBB2, PGR
8fulvestrant43 49 28 1212.9PGR, ERBB2
9letrozole43 49 59 1212.9ERBB2, PGR
10taxane439.9ERBB2, PGR
11leucovorin43 49 1211.8PGR, ERBB2
12raloxifene43 49 28 1212.7ERBB2, PGR
13trastuzumab43 49 1211.7ERBB2, PGR
144-hydroxytamoxifen439.6PGR, ERBB2
15geldanamycin43 49 59 1212.6ERBB2, PGR
16gnrh439.6ERBB2, NKX2-1, PGR
17progestin439.5ERBB2, PGR
18cyclophosphamide43 49 1211.5ERBB2, MUC16, PGR
19ribonucleic acid439.4KRT20, NKX2-1, PGR
20paclitaxel43 49 1211.3PGR, MUC16, ERBB2
21streptavidin439.3KRT20, KRT7
22carboplatin43 49 1211.2ERBB2, MUC16
23methotrexate49 43 1211.1PGR, ERBB2, KRT7
24steroid439.1PGR, MUC16, NKX2-1, ERBB2
25dexamethasone43 49 28 1212.1ERBB2, NKX2-1, MUC16, PGR
26mucicarmine439.1KRT20, KRT7, NKX2-1
27doxorubicin43 49 1210.8PGR, MUC16, ERBB2, KRT20
28iron43 249.7KRT20, KRT7, MUC16
29formaldehyde43 249.6NKX2-1, ERBB2, KRT7, KRT20
30b 723438.5MUC16, NKX2-1, KRT7, KRT20
31hematoxylin438.5MUC16, NKX2-1, KRT7, KRT20
32testosterone43 59 24 1211.0KRT20, KRT7, ERBB2, MUC16, PGR
33vegf438.0PGR, MUC16, ERBB2, KRT7, KRT20
34paraffin437.7KRT20, KRT7, ERBB2, NKX2-1, MUC16, PGR
35progesterone43 28 59 24 1211.7PGR, MUC16, NKX2-1, ERBB2, KRT7, KRT20
36estrogen437.7PGR, MUC16, NKX2-1, ERBB2, KRT7, KRT20
37tyrosine437.5MUC16, ANXA4, NKX2-1, ERBB2, KRT7, KRT20

GO Terms for genes affiliated with Papillary Serous Adenocarcinoma

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Cellular components related to Papillary Serous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.0KRT20, KRT7

Molecular functions related to Papillary Serous Adenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055157.3KRT20, KRT7, ERBB2, NKX2-1, MUC16, PGR

Products for genes affiliated with Papillary Serous Adenocarcinoma

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  • Antibodies
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  • Kits and Assays

Sources for Papillary Serous Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet