MCID: PPL022
MIFTS: 66

Papilloma malady

Cancer diseases category
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Summaries for Papilloma

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Disease Ontology:8 A cell type benign neoplam that is composed of epithelial tissue on papillae of vascularized connective tissue.

MalaCards based summary: Papilloma, also known as papillomatosis, is related to choroid plexus papilloma and inverted papilloma. An important gene associated with Papilloma is UBE3A (ubiquitin protein ligase E3A), and among its related pathways are Transcriptional activation of cell cycle inhibitor p21 and GADD45 Pathway. The drugs podophyllin and podophyllin pwdr and the compounds acnu and 2-methoxyethanol have been mentioned in the context of this disorder. Affiliated tissues include breast, skin and cervix, and related mouse phenotypes are no phenotypic analysis and craniofacial.

Wikipedia:65 Papilloma (plural papillomas or papillomata) (papillo- + -oma) refers to a benign epithelial tumor... more...

Aliases & Classifications for Papilloma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 34MeSH, 57SNOMED-CT, 39NCIt
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Papilloma, Aliases & Descriptions:

Name: Papilloma 8 10 44 62
Papillomatosis 8 44 62
 
Papillomatosis, Nos 8
Papillomatosis Nos 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:2615
MeSH34 D010212
NCIt39 C7440

Related Diseases for Papilloma

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Diseases related to Papilloma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 397)
idRelated DiseaseScoreTop Affiliating Genes
1choroid plexus papilloma32.4TP53
2inverted papilloma32.0MKI67, KRT13, CDKN1B
3ductal carcinoma in situ31.0TP53
4leukoplakia30.8MKI67, KRT13
5oral leukoplakia30.6TP63, MKI67
6seborrheic keratosis30.6FGFR3
7cholangiocarcinoma30.5CDKN1B, RASSF1, TP53
8keratoacanthoma30.5MKI67, CDKN1A
9papillary carcinoma30.5CDKN1B, ACTC1, TP63, MKI67
10cervical intraepithelial neoplasia30.5MKI67, BIRC5, CDKN2A
11tongue cancer30.4CDKN1A
12meningioma30.3S100B, MKI67
13li-fraumeni syndrome30.3TP53, CDKN2A
14lung cancer30.1TP63, TP53, BIRC5, CDKN1A
15transitional cell carcinoma30.1MKI67, TP63, TP53, BIRC5, CDKN1A, FGFR3
16histiocytosis30.1S100B
17ependymoma30.0S100B, RASSF1, MKI67
18esophageal cancer30.0TP53, CDKN2A, CDKN1B
19squamous cell carcinoma of the head and neck29.9TP53, BIRC5, RASSF1, CDKN1A, CDKN2A
20dermatofibrosarcoma protuberans29.9ACTC1, S100B
21bladder transitional cell carcinoma29.8MKI67, TP53, BIRC5
22endometrial carcinoma29.8TP53, RASSF1, CDKN2A
23cervical cancer29.8TP53, BIRC5, RASSF1, UBE3A, CDKN1A, CDKN2A
24malignant mixed mullerian tumor29.8S100B, ACTC1, TP53
25basal cell carcinoma29.8ACTC1, TP53, TP63, MKI67
26cervical adenocarcinoma29.7CDKN1B, CDKN2A, CDKN1A, RASSF1
27oral cancer29.6TP53, BIRC5, KRT13, CDKN1A, CDKN2A, CDKN1B
28laryngeal squamous cell carcinoma29.6MKI67, TP63, TP53, BIRC5, CDKN1A, CDKN2A
29prostate cancer29.6MKI67, TP63, BIRC5, CDKN1A, CDKN1B
30leiomyoma29.6S100B, ACTC1, MKI67
31mucoepidermoid carcinoma29.5MKI67, TP63, ACTC1, KRT13, CDKN1B
32medulloblastoma29.4TP53, ACTC1, RASSF1, S100B
33synovial sarcoma29.4MKI67, RASSF1, S100B, KRT13
34sarcoma29.2MKI67, TP63, TP53, ACTC1, S100B
35cervical squamous cell carcinoma29.2MKI67, TP63, RASSF1, CDKN1A, CDKN2A, CDKN1B
36non-small cell lung carcinoma29.1TP63, TP53, BIRC5, RASSF1, CDKN1A, CDKN2A
37retinoblastoma28.9MKI67, TP53, BIRC5, RASSF1, UBE3A, CDKN1A
38colorectal cancer28.9TP53, BIRC5, RASSF1, CDKN1A, CDKN2A, CDKN1B
39adenocarcinoma28.9MKI67, TP63, TP53, ACTC1, BIRC5, RASSF1
40adenoma28.7MKI67, TP63, TP53, ACTC1, BIRC5, RASSF1
41astrocytoma28.6MKI67, TP53, RASSF1, S100B, CDKN1A, CDKN2A
42breast cancer28.6MKI67, TP63, TP53, BIRC5, RASSF1, UBE3A
43glioblastoma28.6TP53, BIRC5, RASSF1, S100B, CDKN1A, CDKN2A
44bladder carcinoma28.5FGFR3, CDKN2A, CDKN1A, RASSF1, BIRC5, ACTC1
45tongue squamous cell carcinoma27.9MKI67, CDKN1B, CDKN2A, CDKN1A, KRT13, RASSF1
46melanoma27.8MKI67, TP63, TP53, ACTC1, BIRC5, RASSF1
47choroiditis11.0
48biliary papillomatosis10.8
49intraductal papilloma10.8
50cervicitis10.8

Graphical network of the top 20 diseases related to Papilloma:



Diseases related to papilloma

Symptoms for Papilloma

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Drugs & Therapeutics for Papilloma

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Drug clinical trials:

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Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Papilloma

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Anatomical Context for Papilloma

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MalaCards organs/tissues related to Papilloma:

32
Breast, Skin, Cervix, Bone, Lung, Testes, Prostate, Salivary gland, Brain, T cells, Lymph node, Endothelial, Tongue, Pineal, Kidney, Ovary, Thyroid, Pituitary, Spinal cord, Smooth muscle, Colon, Liver, Tonsil, Temporal lobe, Trachea

Animal Models for Papilloma or affiliated genes

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MGI Mouse Phenotypes related to Papilloma:

36 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.0TP53, UBE3A, CDKN1A, CDKN2A, CDKN1B, FGFR3
2MP:00053829.0TP63, TP53, CDKN1A, CDKN1B, FGFR3
3MP:00053888.9TP63, TP53, CDKN1A, CDKN2A, CDKN1B, FGFR3
4MP:00053818.9TP63, TP53, CDKN1A, CDKN2A, CDKN1B, FGFR3
5MP:00053918.8TP63, TP53, CDKN1A, CDKN2A, CDKN1B, FGFR3
6MP:00053678.8TP63, TP53, CDKN1A, CDKN1B, FGFR3
7MP:00053798.8TP63, TP53, UBE3A, CDKN1A, CDKN2A, CDKN1B
8MP:00053698.8TP63, TP53, ACTC1, CDKN1A, CDKN2A, CDKN1B
9MP:00053898.7TP63, TP53, UBE3A, CDKN1A, CDKN2A, CDKN1B
10MP:00053858.4CDKN1B, CDKN1A, RASSF1, ACTC1, TP53, TP63
11MP:00020068.4TP63, TP53, RASSF1, CDKN1A, CDKN2A, CDKN1B
12MP:00107718.2TP63, TP53, S100B, UBE3A, CDKN1A, CDKN2A
13MP:00053868.2TP63, TP53, S100B, UBE3A, CDKN1A, CDKN2A
14MP:00053788.2TP63, TP53, ACTC1, UBE3A, CDKN1A, CDKN2A
15MP:00028738.0TP63, TP53, ACTC1, BIRC5, RASSF1, S100B
16MP:00053877.8TP63, TP53, BIRC5, RASSF1, CDKN1A, CDKN2A
17MP:00053847.4FGFR3, TP63, TP53, ACTC1, BIRC5, RASSF1
18MP:00053767.3TP63, TP53, ACTC1, BIRC5, RASSF1, UBE3A
19MP:00107687.3BIRC5, ACTC1, TP53, TP63, RASSF1, UBE3A

Publications for Papilloma

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Articles related to Papilloma:

(show top 50)    (show all 1551)
idTitleAuthorsYear
1
Tendering and value-based pricing: lessons from Italy on human papilloma virus vaccines. (24399770)
2014
2
Relationship among tobacco habits, human papilloma virus (HPV) infection, p53 polymorphism/mutation and the risk of oral squamous cell carcinoma. (25328301)
2014
3
Evaluation of correlation of cell cycle proteins and Ki-67 interaction in paranasal sinus inverted papilloma prognosis and squamous cell carcinoma transformation. (25013792)
2014
4
Malignant transformation of sinonasal inverted papilloma: A retrospective analysis of 32 cases. (25360173)
2014
5
Manipulated Microenvironment in Human Papilloma Virus-Infected Epithelial Cells: Is the CD40-CD154 Pathway Beneficial for Host or Virus? (25381767)
2014
6
Transnasal endoscopic approach with powered instrumentation for treating squamous papilloma in the nasopharyngeal surface of the soft palate. (23351477)
2013
7
Densely calcified atypical choroid plexus papilloma at the cerebellopontine angle in an adult. (24303341)
2013
8
Choroid plexus papilloma of the third ventricle: A rare infantile brain tumor. (24470825)
2013
9
Betulinic acid and possible influence on the clearance of Human Papilloma Virus: cytological and virological follow-up. (23881391)
2013
10
Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood-cerebrospinal fluid barrier. (23000117)
2012
11
A case of choroid plexus papilloma with stromal sclerosis and indistinct papillary structures. (21968641)
2012
12
Inverted papilloma with associated carcinoma of the nasal cavity and paranasal sinuses: treatment outcomes. (22035165)
2012
13
Monophasic epithelial synovial sarcoma accompanied by an inverted papilloma in the sphenoid sinus. (23251173)
2012
14
The expression and significance of smac, XIAP, caspase-3 in nonnasal inverted papilloma]. (23156805)
2012
15
Prevalence of human papillomavirus, Epstein-Barr virus, p21, and p53 expression in sinonasal inverted papilloma, nasal polyp, and hypertrophied turbinate in Hong Kong patients. (21608063)
2012
16
Human papilloma virus transformed CaSki cells constitutively express high levels of functional SerpinB2. (20974129)
2011
17
Human papilloma virus: a new risk factor in a subset of head and neck cancers. (22044803)
2011
18
Persistent, widespread papilloma formation on the penis of a horse: a novel presentation of equine papillomavirus type 2 infection. (21645140)
2011
19
Molecular variants of human papilloma viruses type 16 and 6 in women with different cytological results detected by RFLP analysis. (20977078)
2010
20
Predictors of human papilloma virus (HPV) infection in Italian women. (20872720)
2010
21
Polyploidy in atypical grade II choroid plexus papilloma of the posterior fossa. (18627486)
2009
22
Multiple dicentric chromosomes behind polyploidy in grade II atypical choroid plexus papilloma: a complementary cytogenetic evaluation. (19077039)
2009
23
Primary choroid plexus papilloma of the sacral nerve roots. (19119933)
2009
24
The evolution of management for inverted papilloma: an analysis of 200 cases. (19248937)
2009
25
Prevalence of leukoplakia, oral submucous fibrosis, papilloma and its relation with stress among green marbles mine laborers, India. (18978707)
2008
26
Sinonasal inverted papilloma: value of convoluted cerebriform pattern on MR imaging. (18499786)
2008
27
Positron emission tomography for predicting malignancy of sinonasal inverted papilloma. (17413572)
2007
28
Clinical photographic quiz. Nasal polyposis, inverted papilloma, sino-nasal tumour, rhinoscleroma. (16649466)
2006
29
High-risk human papilloma virus infection decreases the frequency of dendritic Langerhans' cells in the human female genital tract. (16423058)
2006
30
Therapeutic potential of an adenovirus expressing p73 beta, a p53 homologue, against human papilloma virus positive cervical cancer in vitro and in vivo. (16481734)
2006
31
Cytokeratins in papillary lesions of the breast: is there a role in distinguishing intraductal papilloma from papillary ductal carcinoma in situ? (15832086)
2005
32
Intraductal papilloma with "comedo-like" necrosis, a diagnostic pitfall. (15494933)
2004
33
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. (12566297)
2003
34
Serum squamous cell carcinoma antigen is a useful biologic marker in patients with inverted papillomas of the sinonasal tract. (11815971)
2002
35
Choroid plexus papilloma in the posterior cranial fossa: MR, CT, and angiographic findings. (11679220)
2001
36
Aggressive endoscopic resection of inverted papilloma: an update. (11458214)
2001
37
Choroid plexus papilloma of cerebellopontine angle with extension to foramen magnum. (10339715)
1999
38
Glandular-type inverted papilloma of the prostatic urethra. (9406482)
1997
39
Expression of p53, Ki-67 and cytokeratin-4 (CK4) in oral papillomas. (9178172)
1997
40
The standard isoform of CD44 is preferentially expressed in atypical papillomas and carcinomas of the choroid plexus. (9182293)
1996
41
Esophageal squamous cell papilloma, suspected of squamous cell carcinoma. (8012070)
1993
42
Cytological appearances of a solitary squamous cell papilloma with associated mucous gland adenoma in the lung. (1421008)
1992
43
Pathologic quiz case 1. Nasal papillomatosis (inverted papilloma); adenocarcinoma of the ethmoid sinus resembling colonic carcinoma. (3566957)
1987
44
Inverted papilloma of the ureter: two cases of conservative therapy. (3582442)
1987
45
A novel type of human papilloma virus DNA from the lesion of epidermodysplasia verruciformis. (3023264)
1986
46
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice. (6231135)
1984
47
Choroid plexus papilloma with cerebrospinal fluid rhinorrhea. (6495170)
1984
48
Inhibition by quercetin of the promoting effect of teleocidin on skin papilloma formation in mice initiated with 7,12-dimethylbenz[a]anthracene. (6428958)
1984
49
Proptosis and pseudocyst formation from inverted papilloma. (7114673)
1982
50
Malignant inverted papilloma characterized by proptosis. (937447)
1976

Variations for Papilloma

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Expression for genes affiliated with Papilloma

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Expression patterns in normal tissues for genes affiliated with Papilloma

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Pathways for genes affiliated with Papilloma

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Pathways related to Papilloma according to GeneCards/GeneDecks:

(show all 46)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
10.0CDKN1A, TP53
210.0TP53, CDKN1A
3
Show member pathways
AhR pathway37
9.9CDKN1B, CDKN1A
49.9TP53, CDKN2A
59.9CDKN2A, TP53
69.8TP53, BIRC5
79.7TP63, TP53, CDKN1A
89.6TP53, CDKN1A, CDKN1B
9
Show member pathways
ErbB receptor signaling network37
ErbB signaling pathway37
9.6TP53, CDKN1A, CDKN1B
109.6CDKN1B, CDKN1A, TP53
119.6CDKN1B, CDKN1A, TP53
129.6CDKN1B, CDKN1A, TP53
13
Show member pathways
Immune response IL 4 signaling pathway60
Signal transduction AKT signaling60
9.6CDKN1B, CDKN1A, TP53
14
Show member pathways
9.6CDKN1B, CDKN1A, TP53
159.6CDKN1B, CDKN1A, TP53
169.6CDKN2A, CDKN1A, TP53
17
Show member pathways
9.6FGFR3, CDKN1B, CDKN1A
18
Show member pathways
9.5CDKN1A, CDKN2A, CDKN1B
19
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation60
9.5CDKN1A, CDKN2A, CDKN1B
209.5CDKN1A, BIRC5, TP53
21
Show member pathways
Signal transduction PTEN pathway60
9.5CDKN1A, BIRC5, TP53
22
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways60
9.5CDKN1A, BIRC5, TP53
23
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
9.4CDKN1B, CDKN1A, BIRC5
24
Show member pathways
9.3TP53, CDKN1A, CDKN1B, FGFR3
259.3TP53, CDKN1A, CDKN1B, FGFR3
269.3TP53, CDKN1A, CDKN1B, FGFR3
27
Show member pathways
9.3TP63, TP53, CDKN1A, CDKN2A
289.3TP53, CDKN1A, CDKN2A, CDKN1B
29
Show member pathways
9.3TP53, CDKN1A, CDKN2A, CDKN1B
30
Show member pathways
Cell cycle37
9.3TP53, CDKN1A, CDKN2A, CDKN1B
319.3TP53, CDKN1A, CDKN2A, CDKN1B
32
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
9.3TP53, CDKN1A, CDKN2A, CDKN1B
33
Show member pathways
DNA damage response37
9.3TP53, CDKN1A, CDKN2A, CDKN1B
34
Show member pathways
9.3CDKN1B, CDKN2A, CDKN1A, TP53
35
Show member pathways
9.3CDKN1B, CDKN2A, CDKN1A, TP53
36
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
9.2TP53, BIRC5, CDKN1A, CDKN1B
37
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
9.1CDKN2A, BIRC5, TP53, TP63
38
Show member pathways
9.1FGFR3, CDKN1B, CDKN1A, S100B
399.0TP53, UBE3A, CDKN1A, CDKN2A, CDKN1B
40
Show member pathways
9.0TP53, CDKN1A, CDKN2A, CDKN1B, FGFR3
41
Show member pathways
8.8TP53, BIRC5, CDKN1A, CDKN2A, CDKN1B
42
Show member pathways
8.6MKI67, TP63, TP53, CDKN1A, CDKN2A, CDKN1B
43
Show member pathways
Signaling Pathways in Glioblastoma37
8.3TP53, RASSF1, CDKN1A, CDKN2A, CDKN1B, FGFR3
44
Show member pathways
8.3TP53, BIRC5, UBE3A, CDKN1A, CDKN2A, CDKN1B
458.1FGFR3, TP63, TP53, RASSF1, CDKN1A, CDKN2A
467.9TP53, BIRC5, RASSF1, CDKN1A, CDKN2A, CDKN1B

Compounds for genes affiliated with Papilloma

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Compounds related to Papilloma according to GeneCards/GeneDecks:

(show top 50)    (show all 130)
idCompoundScoreTop Affiliating Genes
1acnu449.9TP53, CDKN1A, CDKN2A
22-methoxyethanol449.9TP63, UBE3A, ACTC1
3hpvs449.8TP53, UBE3A, CDKN1A, CDKN2A
4noxa449.6TP63, TP53, BIRC5, CDKN1A
5indole-3-carbinol449.5TP53, BIRC5, CDKN1A, CDKN1B
6leptomycin b44 6110.5CDKN1A, CDKN1B, TP53, BIRC5
7roscovitine449.5CDKN1A, CDKN2A, BIRC5, TP53
8mimosine44 1110.4CDKN1B, BIRC5, CDKN1A
9mucicarmine449.4ACTC1, S100B, TP63
10irinotecan44 50 1111.4TP53, CDKN2A, CDKN1A, MKI67
11p00001449.3BIRC5, CDKN1B, MKI67, CDKN2A
12bortezomib44 50 1111.3FGFR3, CDKN1B, CDKN1A, BIRC5, TP53
137,12-dimethylbenz(a)anthracene449.3BIRC5, KRT13, CDKN2A
14celecoxib44 61 28 50 24 1114.3BIRC5, MKI67, CDKN1A, CDKN1B
15flavopiridol44 1110.2CDKN2A, CDKN1A, BIRC5, CDKN1B, TP53
16camptothecin44 61 1111.2CDKN2A, CDKN1B, CDKN1A, BIRC5, TP53
17egcg449.2BIRC5, CDKN1A, CDKN2A, CDKN1B, TP53
18mg 13244 6110.2CDKN1B, CDKN2A, TP53, BIRC5, CDKN1A
19crcs449.2BIRC5, CDKN2A, TP53, RASSF1
20thymidylate449.1TP53, BIRC5, CDKN1A, CDKN2A, MKI67
21mitomycin c449.1BIRC5, TP63, TP53, MKI67
22bromodeoxyuridine449.0TP63, MKI67, CDKN1B, CDKN1A, S100B
23n acetylcysteine449.0BIRC5, CDKN1A, TP53, CDKN1B, CDKN2A
24hematoxylin449.0CDKN2A, MKI67, S100B, TP63, ACTC1
25butyrate449.0CDKN2A, CDKN1A, BIRC5, CDKN1B, TP53
26tamoxifen44 50 28 1111.9MKI67, CDKN1B, TP53, BIRC5, CDKN1A
27etoposide44 50 61 1111.9TP53, BIRC5, S100B, CDKN1B, CDKN1A
28gemcitabine44 50 1110.9CDKN1B, TP53, CDKN1A, BIRC5
295fluorouracil448.8CDKN1B, BIRC5, CDKN2A, MKI67, TP53, CDKN1A
30agar448.7BIRC5, CDKN2A, RASSF1, CDKN1A, CDKN1B
31p003448.7MKI67, RASSF1, S100B, CDKN1B, TP63
32imatinib44 50 1110.7CDKN1A, CDKN1B, S100B, BIRC5, ACTC1, FGFR3
33cycloheximide448.7CDKN1A, CDKN1B, BIRC5, TP53, MKI67, CDKN2A
34thymidine44 249.4MKI67, TP63, CDKN1A, S100B, CDKN1B, BIRC5
35arginine448.4MKI67, CDKN1B, CDKN2A, FGFR3, S100B, TP53
36paclitaxel44 50 1110.3TP53, CDKN1A, MKI67, BIRC5, CDKN1B, CDKN2A
37oligonucleotide448.2RASSF1, CDKN1A, CDKN2A, CDKN1B, TP53, BIRC5
38steroid448.2CDKN2A, UBE3A, MKI67, TP63, ACTC1, BIRC5
39testosterone44 61 24 1111.2TP63, CDKN2A, CDKN1B, BIRC5, MKI67, S100B
40oxygen44 249.1MKI67, CDKN2A, CDKN1B, CDKN1A, S100B, BIRC5
41doxorubicin44 50 1110.0CDKN1B, FGFR3, TP63, CDKN2A, CDKN1A, UBE3A
42cisplatin44 50 61 1110.9BIRC5, TP63, TP53, CDKN1B, CDKN2A, CDKN1A
43progesterone44 28 61 24 1111.7MKI67, TP63, TP53, ACTC1, BIRC5, S100B
44tyrosine447.7CDKN1B, CDKN1A, UBE3A, S100B, BIRC5, TP63
45threonine447.6BIRC5, CDKN1A, CDKN2A, FGFR3, S100B, RASSF1
46vegf447.4TP63, TP53, ACTC1, MKI67, BIRC5, S100B
47serine447.4CDKN1A, BIRC5, TP53, MKI67, RASSF1, S100B
48paraffin447.2KRT13, CDKN2A, S100B, CDKN1B, FGFR3, BIRC5
49estrogen446.8MKI67, TP63, TP53, ACTC1, BIRC5, RASSF1
50retinoic acid44 247.8RASSF1, BIRC5, ACTC1, TP53, TP63, MKI67

GO Terms for genes affiliated with Papilloma

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Cellular components related to Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:0166049.9CDKN2A, TP53
2nucleoplasmGO:0056548.7TP63, TP53, CDKN1A, CDKN2A, CDKN1B
3cytosolGO:0058297.9TP63, TP53, ACTC1, BIRC5, UBE3A, CDKN1A
4nucleusGO:0056346.4BIRC5, TP53, TP63, MKI67, RASSF1, S100B
5cytoplasmGO:0057375.9CDKN1B, MKI67, TP63, TP53, ACTC1, BIRC5

Biological processes related to Papilloma according to GeneCards/GeneDecks:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1mitotic G1 DNA damage checkpointGO:03157110.3TP53, TP63
2DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:00697810.3TP63, TP53
3response to X-rayGO:01016510.2TP53, TP63
4replicative senescenceGO:09039910.2CDKN2A, TP53
5positive regulation of cell cycle arrestGO:07115810.2TP53, CDKN2A
6cell agingGO:00756910.1TP53, TP63
7cellular response to ionizing radiationGO:07147910.1CDKN1A, TP53
8cellular senescenceGO:09039810.1CDKN2A, CDKN1A
9intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:04277110.1CDKN1A, TP53, TP63
10mitotic cell cycle arrestGO:07185010.0TP53, CDKN1A, CDKN1B
11positive regulation of reactive oxygen species metabolic processGO:200037910.0TP53, CDKN1A
12DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:00697710.0TP53, CDKN1A, CDKN1B
13negative regulation of cyclin-dependent protein serine/threonine kinase activityGO:0457369.9CDKN1A, CDKN2A, CDKN1B
14negative regulation of phosphorylationGO:0423269.9CDKN1B, CDKN2A, CDKN1A
15phosphatidylinositol-mediated signalingGO:0480159.9FGFR3, CDKN1B, CDKN1A
16response to gamma radiationGO:0103329.9TP63, TP53
17fibroblast growth factor receptor signaling pathwayGO:0085439.8CDKN1A, CDKN1B, FGFR3
18G1/S transition of mitotic cell cycleGO:0000829.8CDKN1B, CDKN2A, CDKN1A
19Fc-epsilon receptor signaling pathwayGO:0380959.8FGFR3, CDKN1B, CDKN1A
20epidermal growth factor receptor signaling pathwayGO:0071739.8CDKN1A, CDKN1B, FGFR3
21cellular response to UVGO:0346449.7TP53, TP63
22negative regulation of cell growthGO:0303089.6TP53, CDKN1A, CDKN2A, CDKN1B
23negative regulation of cell proliferationGO:0082859.6TP53, CDKN1A, CDKN2A, CDKN1B
24cellular response to DNA damage stimulusGO:0069749.6TP53, RASSF1, CDKN1A
25mitotic cell cycleGO:0002789.4BIRC5, CDKN1A, CDKN2A, CDKN1B
26Ras protein signal transductionGO:0072659.4CDKN2A, CDKN1A, RASSF1, TP53
27positive regulation of cell proliferationGO:0082849.2BIRC5, S100B, CDKN1B, FGFR3
28negative regulation of transcription, DNA-templatedGO:0458929.2TP63, TP53, BIRC5, CDKN2A, CDKN1B
29apoptotic processGO:0069159.2BIRC5, ACTC1, TP53, TP63
30innate immune responseGO:0450879.1FGFR3, CDKN1B, CDKN1A, S100B
31cell cycle arrestGO:0070509.0CDKN1B, CDKN2A, CDKN1A, RASSF1, TP53
32negative regulation of apoptotic processGO:0430669.0TP63, TP53, ACTC1, BIRC5, CDKN1A, CDKN1B

Molecular functions related to Papilloma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MDM2/MDM4 family protein bindingGO:0973719.9CDKN2A, TP53
2cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.6CDKN1B, CDKN2A, CDKN1A
3chaperone bindingGO:0510879.4CDKN1B, BIRC5, TP53
4p53 bindingGO:0020399.3TP63, TP53, CDKN2A
5identical protein bindingGO:0428028.4TP63, TP53, BIRC5, RASSF1, S100B
6protein bindingGO:0055156.5MKI67, TP63, TP53, BIRC5, RASSF1, S100B

Products for genes affiliated with Papilloma

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Sources for Papilloma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet